another angry kid but a different ending

2
GlaxoSmithKline 2009-10 Johnson & Johnson Novartis Pfizer/Wyeth Merck/Schering Sanofi-Aventis Bristol-Myers AstraZeneca Eli Lilly Abbott 0 5 10 15 20 25 CAN THE PIPELINE PRODUCE? An analysis by Morningstar scored 10 major pharmaceutical companies’ pipelines for market potential. Eli Lilly ranks near the bottom. Source: Morningstar and company reports The Star 2011-12 2013-14 By John Russell [email protected] Mike Heathman looked closely at a computer screen filled with graphs and charts, trying to get a clue about how well an experimental drug for diabetes was working at seven differ- ent dose levels. “Let’s take a look at how this dose worked on heavy patients,” said Heathman, whose job at Eli Lilly and Co. is to build math- ematical models that help scien- tists predict how well drugs work in all types of patients. Around him, spread out in buildings on Lilly’s campus south of Downtown, more than 1,000 computers crunched mountains of data by the second. In the past two years, Lilly has spent millions to upgrade its com- puter-modeling systems, which help scientists decide more quickly how many patients to enroll in a trial and how many levels of doses to test. Doing so cuts the odds that a trial will drag out, running up costs without producing any con- clusive findings. Around Lilly, cutting costs and picking up the pace are the new marching orders. How well every- one executes those orders could determine whether the 133-year- old company can remain strong and independent. PROFIT OR PERIL? IN LILLY’S PIPELINE: LOW: 61 HIGH: 75 Scattered showers and thunderstorms are likely. Details, Page A22 Today’s weather Caption Gary Varvel's latest editorial cartoon Share your caption for a health-care reform cartoon at Indy Star.com/varvel. Get breaking news on your cell phone Text INDYNEWS to 44636 (4INFO) for breaking-news headlines as they happen. SUNDAY, SEPTEMBER 20, 2009 “Where the spirit of the Lord is, there is liberty” II COR. 3:17 $1.75 CITY EDITION INDEX » Lottery A2 » Obituaries B4-6 » Editorials B8 » Scoreboard C15 » Movies IndySunday, 15-16 » Puzzles IndySunday, 31-32 » TV IndySunday, 19-30 BRING ON ROUND 2! FEVER 81, MYSTICS 74, OT $ 164 in savings inside » See Lilly, Page A8 By Ted Evanoff [email protected] The gnawing question for Indi- anapolis — what if Eli Lilly and Co. scientists fall short? — seems almost unthinkable in a region where the giant drug maker is the corporate mainstay. But the company is clearly rac- ing to replace a wave of drugs that will lose patent protection — a race that could put the local economy on a roller-coaster ride if Lilly stumbles. Though the metropolitan area’s $90 billion economy has grown far bigger than just Lilly, the com- pany remains a vital force. It pumps out a $1.5 billion annual payroll and helps support hun- dreds of vendors, ranging from construction firms such as Brown- ing Investments to research part- ners such as Covance. And nowhere is Lilly more Indy would feel the fallout should drug maker stumble » See Fallout, Page A8 More coverage inside: As part of its restructuring, Lilly should consider changing how it governs itself, columnist Daniel Lee writes. A18 T he young man sat slumped in a chair, his eyes staring at the carpet below him and his hands cuffed behind his back. A few feet away, Sgt. John Bar- row sat in another chair. He was leaning back and frowning, shak- ing his head and wondering why another Manual High School stu- dent had jeopardized his educa- tion and, at least temporarily, his freedom. “You just couldn’t look past 30 seconds of anger,” Barrow said. “Why didn’t you just talk to them? All you needed to do was explain yourself.” The student, a 14-year-old freshman named Patrick, paused. Then, barely above a whisper, he said, “I know.” “What?” Barrow demanded, speaking louder. “I know, sir,” Patrick said. About 30 minutes earlier, Pat- rick had been wandering the halls after the late bell and shouting ob- scenities. A teacher, Bob Lyon, had approached him and asked why he Another angry kid — but a different ending Matthew Tully THE MANUAL PROJECT This is the sixth in an occasional series of col- umns Matthew Tully is writing about life at Manual High School. In coming months, he’ll continue to tell the story of the school through the eyes of teachers, administra- tors, students and par- ents. You can read past columns and follow his time at the school on his blog, “Manual Pro- ject,” at IndyStar.com/ MatthewTully. » See Tully, Page A16 By John Tuohy [email protected] When Urie Guerrier hops in his car and drives to cam- pus, his mind could be on an upcoming test or a looming deadline for an assignment. But Guerrier is a student at Indiana University-Pur- due University Indianapolis. So he’s stressing about something more basic: Will he find a place to park? “The parking is something you start thinking about as soon as you leave the house,” said Guerrier, 20, a junior in his first year at IUPUI. He has been late three times this young semester. Numbers paint a pretty good picture of the parking problems: The sprawling Near-Westside campus has 30,000 students — up 5 per- cent from last semester — and 7,000 student parking spots spread across 70 lots and nine garages. “It can be horrible finding MATT KRYGER / The Star SEEKING: Parking lots, garages and lawns fill quickly at IUPUI. Construction of a 1,300-car parking garage will start this fall. 30,000 students, 7,000 parking spaces » See Parking, Page A16 Wheels on the cars go round and round for IUPUI students hunting for an open spot Now get Coupons on your cell phone! Text GROCERY to 22888 IUPUI Moves Up in U.S. News and World Report Ranking for Universities to Watch. —— IUPUI CHANCELLOR: CHARLES R. BANTZ FEVER HEAD TO CONFERENCE FINALS IN DETROIT. C1 As Lilly rolls out its restructuring, some analysts wonder whether it’s too late

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Page 1: Another angry kid but a different ending

GlaxoSmithKline

2009-10

Johnson & Johnson

Novartis

Pfizer/Wyeth

Merck/Schering

Sanofi-Aventis

Bristol-Myers

AstraZeneca

Eli Lilly

Abbott

0 5 10 15 20 25

CAN THE PIPELINE PRODUCE?An analysis byMorningstar scored 10major pharmaceutical companies’pipelines formarket potential. EliLilly ranks near the bottom.

Source: Morningstar and company reports The Star

2011-12 2013-14

By John [email protected]

Mike Heathman looked closely ata computer screen filled with graphsand charts, trying to get a clue abouthow well an experimental drug fordiabetes was working at seven differ-ent dose levels.

“Let’s take a look at how thisdose worked on heavy patients,”said Heathman, whose job at EliLilly and Co. is to build math-ematical models that help scien-tists predict how well drugs workin all types of patients.

Around him, spread out inbuildings on Lilly’s campus southof Downtown, more than 1,000computers crunched mountains ofdata by the second.

In the past two years, Lilly hasspent millions to upgrade its com-puter-modeling systems, whichhelp scientists decide more quicklyhow many patients to enroll in atrial and how many levels of dosesto test. Doing so cuts the odds thata trial will drag out, running upcosts without producing any con-clusive findings.

Around Lilly, cutting costs and

picking up the pace are the newmarching orders. How well every-one executes those orders coulddetermine whether the 133-year-old company can remain strongand independent.

PROFITOR PERIL?

IN LILLY’S PIPELINE:

LOW: 61 HIGH: 75Scattered showers andthunderstorms are likely.Details, Page A22

Today’s weather Caption Gary Varvel'slatest editorial cartoonShare your caption for ahealth-care reform cartoonat Indy Star.com/varvel.

Get breaking news on your cell phoneText INDYNEWS to 44636(4INFO) for breaking-newsheadlines as they happen.

SUNDAY, SEPTEMBER 20, 2009 ✭ “Where the spirit of the Lord is, there is liberty” II COR. 3:17 ✭ $1.75 ✭ CITY EDITION

INDEX » Lottery A2 » Obituaries B4-6 » Editorials B8» Scoreboard C15 » Movies IndySunday, 15-16

» Puzzles IndySunday, 31-32» TV IndySunday, 19-30

BRING ON ROUND 2!FEVER 81, MYSTICS 74, OT

$164in savings

inside

» See Lilly, Page A8

By Ted [email protected]

The gnawing question for Indi-anapolis — what if Eli Lilly andCo. scientists fall short? — seemsalmost unthinkable in a regionwhere the giant drug maker is thecorporate mainstay.

But the company is clearly rac-ing to replace a wave of drugs thatwill lose patent protection — arace that could put the localeconomy on a roller-coaster ride ifLilly stumbles.

Though the metropolitan area’s$90 billion economy has grown farbigger than just Lilly, the com-pany remains a vital force. It

pumps out a $1.5 billion annualpayroll and helps support hun-dreds of vendors, ranging fromconstruction firms such as Brown-ing Investments to research part-ners such as Covance.

And nowhere is Lilly more

Indy would feel the falloutshould drug maker stumble

» See Fallout, Page A8

More coverage inside: As part of its restructuring, Lilly shouldconsider changing how it governs itself, columnist Daniel Lee writes. A18

The young man satslumped in a chair, hiseyes staring at the carpetbelow him and his hands

cuffed behind his back.A few feet away, Sgt. John Bar-

row sat in another chair. He wasleaning back and frowning, shak-ing his head and wondering whyanother Manual High School stu-dent had jeopardized his educa-tion and, at least temporarily, hisfreedom.

“You just couldn’t look past 30seconds of anger,” Barrow said.“Why didn’t you just talk to them?All you needed to do was explainyourself.”

The student, a 14-year-oldfreshman named Patrick, paused.Then, barely above a whisper, hesaid, “I know.”

“What?” Barrow demanded,speaking louder.

“I know, sir,” Patrick said.About 30 minutes earlier, Pat-

rick had been wandering the hallsafter the late bell and shouting ob-scenities. A teacher, Bob Lyon, hadapproached him and asked why he

Another angry kid —but a different ending

Matthew Tully

THE MANUALPROJECT

This is the sixth in anoccasional series of col-umns Matthew Tully is

writing about life atManual High School. Incoming months, he’llcontinue to tell thestory of the schoolthrough the eyes of

teachers, administra-tors, students and par-ents. You can read pastcolumns and follow histime at the school onhis blog, “Manual Pro-ject,” at IndyStar.com/

MatthewTully.

» See Tully, Page A16

By John [email protected]

When Urie Guerrier hopsin his car and drives to cam-pus, his mind could be on anupcoming test or a loomingdeadline for an assignment.

But Guerrier is a studentat Indiana University-Pur-due University Indianapolis.So he’s stressing aboutsomething more basic: Willhe find a place to park?

“The parking is somethingyou start thinking about assoon as you leave the house,”

said Guerrier, 20, a junior inhis first year at IUPUI. Hehas been late three times thisyoung semester.

Numbers paint a prettygood picture of the parkingproblems: The sprawlingNear-Westside campus has30,000 students — up 5 per-cent from last semester —and 7,000 student parkingspots spread across 70 lotsand nine garages.

“It can be horrible finding

MATT KRYGER / The Star

SEEKING: Parking lots, garages and lawns fill quickly at IUPUI.Construction of a 1,300-car parking garage will start this fall.

30,000 students,7,000 parking spaces

» See Parking, Page A16

Wheels on the cars go round and roundfor IUPUI students hunting for an open spot

Now getCouponson your cell phone!Text GROCERY to 22888

IUPUI Moves Up in U.S. News and World ReportRanking for Universities to Watch.—— IUPUI CHANCELLOR: CHARLES R. BANTZ

FEVER HEAD TO CONFERENCE FINALS IN DETROIT. C1

As Lilly rolls out its restructuring, someanalysts wonder whether it’s too late

Page 2: Another angry kid but a different ending

A16 » SUNDAY, SEPTEMBER 20, 2009 2 N D THE INDIANAPOLIS STAR » INDYSTAR.COM

wasn’t in class. It was a simple question,but Patrick wouldn’t cooperate. Heshoved the teacher aside and kept walk-ing. When Lyon stopped him again, Pat-rick swiped away the teacher’s arm.

Patrick was soon in the dean’s office,where he wouldn’t talk and refused toprovide basic information about himself.He tried to look tough and act as if hedidn’t care. His defiance pushed the mat-ter to the next level; he was arrested andturned over to Barrow, head of theManual police force.

Things didn’t look good. Expulsion anda battery charge were likely. A lost schoolyear. Another sad story.

But the student got a break by landingin Barrow’s office. The 44-year-old ser-geant spends his days acting as much likea social worker as a police officer. Hedidn’t want to see Patrick face the type ofsetback many students never overcome.

Not for this. Not this early in his highschool career. So he lectured. He talkedabout the future. He used his favoritephrase — “every pencil has an eraser” — ashe urged Patrick to make the next decisionthe right one.

Patrick still didn’t seem to care. Frus-trated, Barrow wished him good luck withthe tough-guy routine. Then he leanedback, crossed his arms and loudly slappedhis feet on his desk. If you really want tobe tough, Barrow said, do that whenyou’re told to stand in front of the sen-tencing judge.

That got through. Patrick smiledslightly and then started talking. He saidhe didn’t want to be expelled. Or ar-rested. He knew he’d made a mistake.Barrow listened. Barrow told me laterthat he was stunned that his lecture hadworked.

Fortunately, this wasn’t a serious crimi-nal case. Pushing a teacher isn’t accept-able. But it didn’t compare to a recent in-cident in which a student shoved ateaching assistant against a classroomwall. It wasn’t as bad as another incidentin which a student shouted and cursed ata teacher, threatening to slap the “glasses

off your face.”Since Patrick hadn’t gone nearly that far

and had finally admitted his mistake, Bar-row thought a second chance was in order.He reached for his office phone and calledLyon’s classroom. As the phone rang, heturned to Patrick.

“I’m about to sell my soul for you,” hesaid, before asking Lyon to come to his of-fice.

While waiting for the teacher to arrive,Barrow told Patrick to stand up. He un-cuffed him.

“OK, I’m only going to say this once,” hesaid. “Are you listening?”

“Yes,” Patrick said.“What?”“Yes, sir.”Barrow asked the freshman if he had

ever delivered an apology.“Not often, sir.”“Here’s what you need to do. You need

to look him in the eye and when you sayyou’re sorry, you need to be sincere. Youneed to mean it. It has to come from in-side. You were wrong. You made a mis-take. You need to own it. Be a man.”

Lyon arrived a minute or so later. As hestood in the doorway, Barrow asked if he’d

be willing to listen to Patrick’s apologyand consider forgiving him.

Lyon agreed.“The way I acted, I acted offensively,”

Patrick said, quietly but while makingsolid eye contact. “I had a bad day, but Ididn’t mean to take it out on you like that.I’m trying to sincerely apologize to you.”

Lyon quickly accepted the apology,which paved the way for administratorsto limit Patrick’s punishment to a five-daysuspension. Before he left the room,Lyon, a 17-year algebra teacher, shook thestudent’s hand and told him to stop thenext time a teacher asked him a question.

“I know you’re young,” Lyon said. “Weall make mistakes. But we don’t have aproblem. There are no grudges. We’recool.”

After Lyon left, Barrow turned to Pat-rick.

“You could be in jail and expelled,” hesaid. “You see how quick your life canchange? Remember this day for the restof your life. You got a do-over. Do youunderstand?”

“Yes, sir,” Patrick said.✭ Reach Matthew Tully at (317) 444-6033 or viae-mail at [email protected]

Tully» ‘There are no grudges. We’recool,’ teacher says after apology.

From A1

a space,” said Ashley Saviola, 21, a juniorfrom the Castleton area, who is late about10 times a year because she’s looking forparking. “I’ve spent up to 45 minutessearching before.”

Construction of an $18.5 million, 1,300-car parking garage will start this fall, but inthe short term, that’s only adding to theproblem. The project has eliminated sev-eral hundred parking spaces in two lots.

All of which is adding up to a headachenot only for students but for Carol Pferrer,IUPUI’s director of parking and transporta-tion operations.

Her 40-person operation has to be moreprecise than usual. As it is, the departmentruns a kind of perpetual event parking —like herding cars for a basketball game, if anew game started every hour.

“It’s event parking with peaks and val-leys between classes,” Pferrer said. “It canseem like it never ends.”

The school is making some adjustments,parking about 500 cars on the lawn next tothe library and other grassy areas nearparking lots. The university has an AMradio frequency — 1620 — that gives up-dates several times an hour on open park-ing lots. Pferrer wants to send updates tostudents using Twitter next semester.

In addition, the school has renewed its$200,000 yearly contract with IndyGo for afree shuttle bus service between Down-town and the campus. The university alsohas its own free shuttle buses that pick stu-dents up at a free remote parking lot on In-diana Avenue.

On a drive around the university re-cently, Pferrer ordered the emergency “li-brary lawn” parking spots opened at10:45 a.m. when all the other lots and ga-rages were full. A line of cars quickly filedin, leaving a cloud of dust on the dry andtread-worn field as parking enforcementofficer Jonathan Canfield furiously wavedcars through.

John Small popped out of his car at 10:55a.m. The 21-year-old criminal justice majorhad an 11 a.m. class halfway across campus.

“It’s horrible; we are parking in grass,but at least I got a spot,” Small said as hehustled toward class. Small said it usuallytakes him the same amount of time to findparking — 15 minutes — as it does to drivefrom his Southport home. “It’s my first yearhere so I’ll get used to it.”

Canfield, 29, a student who is taking thesemester off to help raise his baby, said hewrites from 50 to 100 tickets a day for park-ing permit violations.

While some students get irritated — he’sbeen challenged to fights — others try togame the system to avoid buying a $181yearly permit or to get a better spot.

The most creative, he said, are the stu-dents at the Herron School of Art.

“They try to forge their permits,” he said.“They do a pretty good job, too, and wouldget a prize for originality if we gave themout.”

Other students try to park in faculty lots

and disguise the student letter designationon their permits by obscuring them behindbeads or slipping them halfway down slitsin the dashboard.

“Give them credit for trying,” he said,“but not too many fool us.”

Not all students are overwhelmed by theparking experience. Some, like DevonJones, 20, Danville, said a little planningcan make life easier.

“They are doing a good job this year oftelling you when places are full so you don’twaste your time driving through a garage,”said the social work major, who has seldombeen late and usually gets the same spoteach day on the top floor of a garage. “Youneed to get here at 8:30 or 9 a.m. to be ableto get right in. I haven’t had a problem thisyear.”

Guerrier said he is learning to adapt.

“On days when I have a class in themorning and another at 6 p.m., I stay oncampus,” he said, “rather than go anywherein my car and lose my spot.”

Tristan Bennett, 18, Lawrence, avoids thehassle by using the free remote lot.

“The commute is long enough as it is,and I don’t want to pay for a permit just so Ican drive another 20 minutes when I gethere,” Bennett said. “The shuttle worksgreat once you have it figured out.”

Student Raymond Pritchett, 24, has an-other solution. He takes the bus the wholeway.

Pritchett lives Downtown and takes theIndyGo Red Line shuttle, saving time andmoney. The fare is free for students whoshow their student identification and a passthey pick up from the school.

“I don’t have a car,” Pritchett said. Buteven if he did, “I don’t know if it wouldmake sense to take it after seeing what it’slike to drive.”✭ Call Star reporter John Tuohyat (317) 444-5526.

Parking» Parking lot updates are givenfrequently each hour on 1620 AM.

From A1

MATT KRYGER / The Star

JUST OPENED: After all the other IUPUI parking spots are filled, parking enforcement officer Jonathan Canfield helps wave vehicles onto thetemporary “library lawn” parking. About 500 can be parked on the grass there.

FREE RIDES: Students get off one of the free shuttle buses that move students and facultyfrom offsite parking to campus and also around campus to help with IUPUI’s parking problem.

“On days when I have a classin the morning and another at6 p.m., I stay on campusrather than go anywhere inmy car and lose my spot.”

Urie Guerrier,a junior in his first year at IUPUI,about the campus parking troubles

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