mapk poster

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SYNkinase Pty. Ltd.Tel: +61 (0)4 1857 0917

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Web: synkinase.com

PP P

P P

JNK CC-401 HCl SYN-1028*

MEK ARRY 334543 SYN-1192* AS703026 SYN-1190* AZD8330 SYN-1195* CH4987655 SYN-1188* CI-1040 SYN-1031* Crizotinib SYN-1139* GSK1120212 SYN-1170* MLN0128 SYN-1157* MPI0479605 HCl SYN-1187* PD0325901 SYN-1059* PP242 SYN-1181*

MKK CI-1040 SYN-1031* Crizotinib SYN-1139*

p38 R1487 HCl SYN-1101* RWJ-67657 SYN-1072* SB-242235 SYN-1076* SB202190 SYN-1073* SB202190 HCl SYN-1073A* SB203580 SYN-1074* SD-06 SYN-1078* SD169 SYN-1079* TAK-715 SYN-1087* VX-702 SYN-1093*

Raf PLX4032 SYN-1161* PLX4720 SYN-1069* SB590885 SYN-1077* Sorafenib SYN-1082* TAK632 SYN-1203* Takeda-6d SYN-1168*

RSK GSK-25 SYN-1124* SR3677 SYN-1083*

SYNkinase Targets Highlighted in Red SYNkinase Products

*Inhibitor available for custom library arrays

MEK1,2

c-Myc/Max

ELK1c-FOS

P

MEK5

ERK1,2

ERK1/2

ERK3-5,7,8

A-Raf, B-Raf, Raf-1

TPL2 MAP3K5

MKK4,7 MKK3,6

MEKK5,7

TAK1

P38α, β, γ, δ

P38α, β, γ, δ

MAPKAPK2,3,5RSK1-3

MNK1,2

JNK1-3

JNK1-3

TAO1,2 Domains

MSK1

MAP3K

MAP2K

MAPK

MAPKAPKTranscription

Factors

c-JUN

JUN

ATF-2

IRF3

Growth Factors &Mitogens

LPS

C/EBPα

STAT1

Inflamatory Cytokines Growth Factors &

Mitogens

GPCRActivation

MSK1

MAP Kinase Signalling Pathway

Adipogen International, Inc.Tel (USA): +1 (858) 457-8383Tel (Swiss): +41-61-926-60-40Email: intl@adipogen.comWeb: www.adipogen.com