mapk poster
TRANSCRIPT
Melbourne • Shanghai • Suzhou • San Diego • Cambridge
SYNkinase Pty. Ltd.Tel: +61 (0)4 1857 0917
US Toll Free: 877-854-6273Email: [email protected]
Web: synkinase.com
PP P
P P
JNK CC-401 HCl SYN-1028*
MEK ARRY 334543 SYN-1192* AS703026 SYN-1190* AZD8330 SYN-1195* CH4987655 SYN-1188* CI-1040 SYN-1031* Crizotinib SYN-1139* GSK1120212 SYN-1170* MLN0128 SYN-1157* MPI0479605 HCl SYN-1187* PD0325901 SYN-1059* PP242 SYN-1181*
MKK CI-1040 SYN-1031* Crizotinib SYN-1139*
p38 R1487 HCl SYN-1101* RWJ-67657 SYN-1072* SB-242235 SYN-1076* SB202190 SYN-1073* SB202190 HCl SYN-1073A* SB203580 SYN-1074* SD-06 SYN-1078* SD169 SYN-1079* TAK-715 SYN-1087* VX-702 SYN-1093*
Raf PLX4032 SYN-1161* PLX4720 SYN-1069* SB590885 SYN-1077* Sorafenib SYN-1082* TAK632 SYN-1203* Takeda-6d SYN-1168*
RSK GSK-25 SYN-1124* SR3677 SYN-1083*
SYNkinase Targets Highlighted in Red SYNkinase Products
*Inhibitor available for custom library arrays
MEK1,2
c-Myc/Max
ELK1c-FOS
P
MEK5
ERK1,2
ERK1/2
ERK3-5,7,8
A-Raf, B-Raf, Raf-1
TPL2 MAP3K5
MKK4,7 MKK3,6
MEKK5,7
TAK1
P38α, β, γ, δ
P38α, β, γ, δ
MAPKAPK2,3,5RSK1-3
MNK1,2
JNK1-3
JNK1-3
TAO1,2 Domains
MSK1
MAP3K
MAP2K
MAPK
MAPKAPKTranscription
Factors
c-JUN
JUN
ATF-2
IRF3
Growth Factors &Mitogens
LPS
C/EBPα
STAT1
Inflamatory Cytokines Growth Factors &
Mitogens
GPCRActivation
MSK1
MAP Kinase Signalling Pathway
Adipogen International, Inc.Tel (USA): +1 (858) 457-8383Tel (Swiss): +41-61-926-60-40Email: [email protected]: www.adipogen.com