3 neumo4 (v3)
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7/29/2019 3 NEUMO4 (v3)
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Nes o`ses sjdbun`rcs
mc n` Dcuieneb`
XENSICD JJJ
_SI@QJE6
Cmjterj`n ?
=.0. @si`, jdhjntr`mes punied`rcs y cesjdehjnj` 3
=.1. Cdhjsci` cd iufcr fevcd de hui`mer` :
=.?. Gcieptjsjs c jdsuhjojcdoj` rcspjr`terj` 0?
=
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DCSIEONDJO@
Cmjtercs6[cmre I`rtd Csorja`de
Fes Nujs Xjcfe A`ucnes
Qc`njz`me per6H@C_Ixjie @bujrrc, 0==7:=; N`ij`oe-Ncej`. Xjzo`y`www.h`cs.cs
Cmjt`me y oeermjd`me per6NSVD 3, _.@. mc Cmjojedcs[`s`fc mc n` Xjrbcd mc n` @ncbr`, 0=.17;12 I`mrjm.c-i`jn6 nuz`dKnuz`d3.csgttp6//www.nuz`d3.cs
]tune erjbjd`n6 DCSIEONDJO@
Oepyrjbgt, 0::7. I`rtd Csorja`de [, Xjcfe A`ucnes FN.
_.X.[. D6 721-N-OI
Mcpsjte ncb`n6 I. 02:8=-0::7Oeipesjojd c jnustr`ojd6 NSVD 3, _.@. mc Cmjojedcs
Jiprjic6 Cbr`h, _.@. I`mrjm.
Qcscrv`mes temes nes mcrcoges. Djdbud` p`rtc mc cst` puanjo`ojd pucmc scr rcpremuojm` dj tr`ds-ijtjm` cd djdbud` heri` e icmje `nbude, cncotrdjoe e icodjoe, jdonuycdme n`s heteoepj`s, br`a`-ojedcs cd ou`nqujcr sjstci` mc rcoupcr`ojd mc `ni`ocd`fc mc jdheri`ojd sjd cn pcrijse csorjtemcn tjtun`r mcn oepyrjbgt.
Oerrcspedmcdoj`6
I`rtd Csorja`de [._crvjoje mc Dcuieneb`. Gespjt`n 01 mc Eotuarc. 17;=0 I`mrjm.]hde. :0 ?:; 71 72. H@W :0 =8: 32 23.c-i`jn6 pic;0iKd`oei.cs
Xjcfe A`ucnes FN._coojd mc Dcuieneb`. Gespjt`n Bcdcr`n Z`bc. ;:;;3 Aurbes]hde. :=2 17 07 ;;
MJXJ_JED BQS[E
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?
d cn `e 0:?8, Rcbcdcr mcsorjaj ud` cdhcricm`m quc sc o`r`otcrjz`a` per `hcot`ojd mc nes
v`ses s`dbudces oed br`dunei`s dcoretjz`dtcs y quc `hcot`a` `n tr`ote rcspjr`terje supcrjer c jdhcrjer
y `n rjd. Cst` cdhcricm`m mc Rcbcdcr oerrcspedmc ` ud brupe is cxtcdse mc cdhcricm`mcs mcsorj-
t`s per Lussi`un y I`jcr g`oc is mc 0;; `es o`r`otcrjz`m`s per v`sounjtjs sjstijo`s dcoretjz`dtcs
oed ncsjedcs cd `rtcrj`s iusoun`rcs mc icmj`de y pcquce t`i`e y cd eo`sjedcs ncsjedcs br`dunei`-
tes`s `seoj`m`s. Cxjstc etr` cdhcricm`m mc o`r`otcrstjo`s sjijn`rcs, oed br`dunei`tesjs y `dbctjs
`nrbjo`, cn sdmreic mc Ogurb-_tr`uss, mcsorjte per cstes utercs cd 0:30 y quc, mjhcrcdoj` mc n` dtc-rjer, cst prcocmjm` o`sj sjciprc mc `si` y rjdjtjs `nrbjo`. Cstes p`ojcdtcs tjcdcd `mcis jdhjntr`mes
punied rcs y `uicdte mc cesjdhjnes cd s`dbrc. Cstc sdmreic cd eo`sjedcs sc iucstr` iuy hnerjme,
h`ojnjt`dme cn mj`bdstjoe, oeie cd cn o`se quc gey prcscdt`ies. Nes oertjoestcrejmcs g`d iestr`me ud`
chjo`oj` det`anc cd su tr`t`ijcdte y `otu`nicdtc n` supcrvjvcdoj` mc cstes p`ojcdtcs cs ne g`ajtu`n.
@nbudes iucstr`d ud ourse rcojmjv`dtc y rcqujcrcd tr`t`ijcdte rcpctjme. Cd nes ntjies `es gcies
`sjstjme ` n` oeiudjo`ojd mc o`ses mc sdmreic mc Ogurb-_tr`uss cd p`ojcdtcs `sitjoes tr`t`mes oed
`dt`bedjst`s mc nes ojstcjdjn-ncuoetrjcdes, sjd pemcr cst`ancocr on`r`icdtc ud` rcn`ojd oed cstc tr`t`-
ijcdte y pesjancicdtc `seoj`mes `n mcsocdse e suprcsjd mc icmjo`ojd oertjoestcrejmc.
Cd cn `e 0:8? N`urcnn y Crjlssed eascrv`red quc trcs jdmjvjmues oed `uscdoj` mc n` a`dm` mc `nh`0
mcn pretcjdebr`i` prcscdt`a`d cdhcricm`m punied`r eastruotjv` ordjo`. [estcrjericdtc sc g`
vjste quc cn mhjojt mc `nh`0-`dtjtrjpsjd` cs ud` cdhcricm`m gcrcmjt`rj` quc sc o`r`otcrjz` per ud`
mjsijduojd mc n`s oedocdtr`ojedcs pn`sitjo`s mc cst` bnuoepretcd` y ouy` i`djhcst`ojd ondjo`
prjdojp`n cs cn cdhjsci` punied r y cd eo`sjedcs n` gcp`tep`t`. Nes jdmjvjmues `hcot`mes y nes h`ij-
nj`rcs oed [jVV tjcdcd ud predstjoe y ud` cxpcot`tjv` mc vjm` iuy v`rj`ancs. N` jdhnucdoj` mcn t`a`-
oe cs mcojsjv`, nncv`dme ` prmjm`s mc HCX0 mc :; in/`e cd de hui`mercs, hrcdtc ` nes ?1; in/`e
mc nes hui`mercs.
Cmjterj`n
C
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Cmjterj`n
=
Cn tcrocr o`se oerrcspedmc ` ud` gciesjmcresjs punied`r jmjeptjo`. _c mcsorjac oeie ud prjicr
ou`mre `bume oed gcieptjsjs y ud` hucrtc `dcijz`ojd, rcpctjme ud ics mcspus y sjd rcojmjv`s cd
cn `e sjbujcdtc. Mcspus mc ud cxg`ustjve cstumje sc nncb` `n mj`bdstjoe per cxonusjd mc etr`s
cdhcricm`mcs. Onsjo`icdtc, pcre de mc heri` sjstcitjo`, sc mcsorjac ud `uicdte cd n` o`p`ojm`m
mc mjhusjd `nvceneo`pjn`r cd nes o`ses mc gcierr`bj` punied`r, y, chcotjv`icdtc, cd cstc o`se t`dtecn v`ner `asenute oeie su oerrcoojd oed cn venuicd `nvcen`r (lOE) cstd cncv`mes.
Nes cmjtercs
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3
`rd mc =3 `es mc cm`m, tr`a`f`mer mc n` oedstruo-
ojd, oed dtcocmcdtcs mc si` aredquj`n cd tr`t`ijcdte oed
1 mc oert` `oojd y aumcsedjm`, penjpesjs d`s`n y cx hui`-mer mcsmc g`oc eoge `es, quc oedsunt` per ou`mre mc trcs
icscs mc cvenuojd oedsjstcdtc cd i`ncst`r bcdcr`n, stcdj`,
`rtr`nbj`s ijbr`terj`s, ij`nbj`s mc prcmeijdje nuia`r, hjc-
arc vcspcrtjd`, tes y mener terojoe.
@n oeijcdze mcn ou`mre sc pr`otjo ud` r`mjebr`h` mc
tr`x quc iestr`a` ud jdhjntr`me `nvcen`r cd ndbun` per ne
quc rcojaj tr`t`ijcdte oed i`ornjmes y is t`rmc quj-
dened`s, sjd xjte.
Cxpner`ojd hsjo`6
Cupdcjoe cd rcpese, oed `p`rcdtc aucd cst`me bcdcr`n y tci-
pcr`tur` mc ?7O. N` jdspcoojd iucstr` cd n` rcbjd pestc-
reocrvjo`n jzqujcrm` ud` ncsjd crjtci`te-vjenoc` mc 3 oi
mc mjictre (hjb. 0). N` `usount`ojd punied`r cvjmcdoj`
redous ajn`tcr`ncs sjcdme `demjde cn rcste mc n` cxpner`ojd.
Cxpner`ojedcs oeipncicdt`rj`s
@d`ntjo` s`dbudc`6 scrjc ref` deri`n. Ncuoeojtes
11.?;;/ii? oed 31% mc cesjdhjnes< X_B 22 ii cd n` prj-icr` ger`. Ajequijo` bcdcr`n, cncotrnjtes, tr`ds`ijd`s`s y
sjstcitjoe mc erjd` mcdtre mc r`dbes deri`ncs. JbB 10?;
ib/mn, JbI :2 ib/mn, JbC 31; ib/in, [OQ =2 ib/n, HQ 73
S/in, @_NE =:;, `dtj-XJG dcb`tjve, @DO@ de mctcot`-
ancs, @D@ dcb`tjves y prcojpjtjd`s hrcdtc ` @spcrbjnnus
dcb`tjv`s.
Ojteneb`s mc cspute6 hretjs jdhn`i`terje oed cesjdhjnes
cdtrc cn =;% y cn 23%.
A`ojnesoepj`s scrj`m`s dcb`tjv`s p`r` A@@Q.
[ruca`s hudojed`ncs rcspjr`terj`s6 HCX0 130; in
(88%), HXO ?08; in (8=%), HCX0/HXO 2:%, IICH23/131.33; in (83%). ]r`s ud aredoemjn`t`mer6 HCX0 127; in
(2?%), HXO ?33; in (20%) (t`an` J).
Coebr`h` o`rmj`o` y `ameijd`n6 deri`ncs.
Q`mjebr`h` mc tr`x6 jdhjntr`mes `nvcen`rcs cd ndbun` y
naune icmje (NI).
]eiebr`h` `xj`n oeiput`rjz`m` (]@O) mc scdes6 sjdusj-
tjs i`xjn`r mcrcog` oed pcquce djvcn gjmre`rce, pnjpes
d`s`ncs, jdhn`i`ojd mcn scde cshcdejm`n y h`nt` mc dcui`tj-
z`ojd mc nes hredt`ncs (hjb. 1). ]@O terojo`6 oedmcds`-
ojd scbicdt`rj` mcn NI oed aredoebr`i` cd su jdtcrjer,
jibcdcs scbicdt`rj`s trj`dbun`rcs pcrjhrjo`s y `uscdoj`
mc `mcdep`t`s (hjb. ?).
@n tcrocr m` mcn jdbrcse cn p`ojcdtc rchjcrc scds`ojd mc
`oerog`ijcdte cd n` pn`dt` mcn pjc jzqujcrme sjd prmj-
m` mc hucrz` `s oeie `p`rjojd mc ncsjedcs refe-vjde-
s`s cd cn aermc jdtcrde mc `iaes pjcs quc hucred jdtcr-
prct`m`s oeie iededcurjtjs intjpnc per v`sounjtjs,oedhjridmesc cn mj`bdstjoe tr`s n` rc`njz`ojd mc
cncotreijebr`i`.
Ajepsj` outdc` cd rcbjd ocrvjoemers`n6 ` djvcn mc n`
mcrijs supcrhjoj`n y icmj` g`y ud i`ro`me jdhjntr`me jdhn`-
i`terje jdtcrstjoj`n y pcrjv`soun r oedstjtujme per cesjdhj-
nes, dcutrhjnes, penjierheduonc`rcs, njdheojtes c gjstjeoj-
tes. Cxjstc ud jdhjntr`me jdtcrstjoj`n pcrj c jdtr`v`soun`r oed
hcdicdes mc v`sounjtjs ncuoeojtepnsjo`, oiunes mc gjs-
=.0. @si`, jdhjntr`mes punied`rcsy cesjdehjnj`
O. MC @A@FE OSOSQSNN, F.N. XJCFE A@SCNE_
_crvjoje mc Dcuieneb`.Gespjt`n Bcdcr`n Z`bc. Aurbes.
X
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tjeojtes, g`ocs mc oenbcde dcores`me remc`mes mc hjarjd`,
penve duonc`r mc cesjdhjnes y penjierheduonc`rcs. N`s
`ntcr`ojedcs gjstenbjo`s sed oeip`tjancs oed sdmreic mc
Ogurb-_tr`uss (hjb. =).
Mj`bdstjoe6 br`dunei`tesjs nrbjo` mc Ogurb-_tr`uss.
Cn p`ojcdtc rcojaj tr`t`ijcdte oed prcmdjsed` ` n` mesjsmc 0 ib/lb/m` oed cxocncdtc rcspucst` ondjo`, r`mjenbj-
o` y `d`ntjo`. Sd `e is t`rmc sjbuc `sjdteitjoe oed
mesjs mc 1,3 ib o`m` =7 ger`s.
Mjsousjd6
Cxjstcd v`rj`s cdtjm`mcs quc ours`d oed cesjdehjnj` c jdhjn-
tr`mes punied`rcs tr`dsjterjes oeie sed6 `spcrbjnesjs
aredoepunied`r `nrbjo` (@A[@), sdmreic gjpcrcesjde-
hnjoe, dcuied` cesjdhjn` `bum` e ordjo` (DCO), br`-
dunei` cesjdhjne, aredqujenjtjs eanjtcr`dtc oed dcuied`erb`djz`m` (AEDE), v`sounjtjs mc Rcbcdcr, sdmreic mc
Ogurb-_tr`uss (_O_), dcuiedjtjs per gjpcrscdsjajnjm`m,
br`dunei`tesjs aredoeodtrjo`, cto.< tem`s cnn`s oed o`r`o-
tcrstjo`s iuy sjijn`rcs y ` icdume mc mjhojn mj`bdstjoe
mjhcrcdoj`n (t`an` JJ).
Cn `dtcocmcdtc mc `si` y n` cxjstcdoj` mc ud tr`sterde eas-
truotjve cd cn cstumje mc hudojd punied`r pucmcd erjcdt`r
g`oj` ud ou`mre mc `si` mc pcrhjn cxtrdscoe, g`oj` ud`@A[@ e g`oj` ud` br`dunei`tesjs mc Ogurb-_tr`uss. Cd cn
cdhcrie quc des eoup` de sc cvjmcdoj`red prcojpjtjd`s
`spcrbjn`rcs, aredqujcot`sj`s dj `ntes v`nercs mc JbC, y sjd
cia`rbe, prcscdt`a` ncsjedcs outdc`s, iededcurjtjs, rtr`n-
bj`s y ij`nbj`s.
Cd 0::; cn @icrjo`d Oenncbc eh Qgcui`teneby mchjdj
scjs orjtcrjes mj`bdstjoes prjdojp`ncs mcn _O_ quc sed6
`si`, cesjdehjnj` s`dbudc` supcrjer `n 0;%, iededcure-
p`t` e penjdcurep`t`, jdhjntr`mes punied`rcs tr`dsjterjes,
`dei`n`s p`r`d`s`ncs y ajepsj` oed v`sounjtjs dcoretjz`d-
tc `hcot`dme ` v`ses mc mjstjdte t`i`e oed jdhjntr`mes
cesjdhjnes y br`dunei`s (t`an` JJJ).
G`y t`iajd orjtcrjes icdercs oeie n` `hcot`ojd o`rmj`o`
cd heri` mc pcrjo`rmjtjs e ijeo`rmjep`t`, rcd`n (pretcjdurj`,
@si`, jdhjntr`mes punied`rcs y cesjdehjnj`
8
]@AN@ J. [ruca`s mc hudojd rcspjr`terj`
HXO ............................................ \nY
HCX 0............................................ \nY
HCX ;,3 ........................................ \nYHCH 23 .......................................... \nY
HCH 3; .......................................... \n/sY
HCH 13 .......................................... \n/sY
[CH ............................................... \n/sY
HCX 0% XO JD ............................ \%Y
CX 0% HXO ................................. \%Y
XO I@W ...................................... \nY
[JH ................................................ \n/sY
IICH 23/13 ................................ \n/sY
HJH 3; ........................................... \n/sY
]crjoe
=,:3
?,7;
?,;?0,?2
=,20
2,:3
:,3=
22,;1
22,;1
3,00
3,=:
?,:?
3,00
Icm 0
?,08
1,30
1,;:;,88
?,0;
8,8;
2,=0
2:,1:
2:,?8
?,08
?,87
1,33
?,37
% (I0/])
8?,:
88,;
8:,1=7,0
83,7
71,:
22,2
0;1,:
0;?,;
80,:
82,;
83,;
2;,;
Icm 1
?,33
1,27
1,??;,8?
?,?;
2,28
2,7;
2:,1;
27,=2
?,33
?,=;
1,12
?,?3
% (IM% (Icm 1 /Icm 0)
20,2
2?,?
22,0=3,8
2;,1
:2,8
70,2
0;1,7
0;0,:
8:,3
80,:
32,8
83,3
01,?
00,;
00,33,?
8,8
02,2
3,1
;,0
0,0
01,1
2,3
00,?
8,=
Hcog` 03/;:/0::7 03/;:/0::7
Hnufe \n/sY
0;
3
;
3
0;
0 1 ? = 3 8 2 7
H/X cs
Xenuicd \nY
H/X jd
Xen % XO I`x
;
1;
3
0;
0 1 ? = 3 8 2 7
H/X cs
Xenuicd \nY
]jcipe \sY
XOI`x
=;
8;
7;
0;;
;
;
0
1
?
=
3
8
2
7
0
1
0
1
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gci`turj`, bneicrunedchrjtjs) e jdtcstjd`n (mj`rrc`, pcrher`-
ojd, gcierr`bj`), quc pumcd scrvjr mc `yum` mj`bdstjo` y
quc iuog`s vcocs oedmjojed`rd cn predstjoe0.
N` prcscdoj` mc ou`tre e is orjtcrjes i`yercs m` ud`
scdsjajnjm`m mcn 73% y ud` cspcojhjojm`m mcn ::,2% cd cn
mj`bdstjoe. Cd eo`sjedcs cs dcocs`rje rcourrjr ` n` rc`nj-
z`ojd mc aredoesoepj` oed n`v`me aredoe`nvcen`r (NA@)
y ajepsj` tr`dsaredquj`n, ` n` vjmceter`oesoepj` c jdonuse
` n` ajepsj` `ajcrt` per ter`oetei`. N` prcv`ncdoj` mc
`dtjoucrpes dtjojtepn`si` mc dcutrhjne (p-@DO@) cs mcn
8;-23%, ijcdtr`s quc nes o-@DO@ sed r`r`icdtc pesjtj-
ves cd cn _O_1,?.
Cd nes ntjies `es sc g`d puanjo`me v`rjes o`ses mc
p`ojcdtcs `sitjoes tr`t`mes oed `dt`bedjst`s mc nes ncu-
oetrjcdes quc g`d mcs`rrenn`me ud _O_ prcojs`dme tr`t`-
ijcdte oed oertjoejmcs=,3,8. @udquc de sc g` mciestr`me
ud` o`us`njm`m mjrcot` mcajm` ` cstes hri`oes, `dtc ud
ou`mre oed i`ro`m` gjpcrcesjdehjnj` y r`mjebr`h` `der-
i`n cs dcocs`rje cst`r `ncrt` y pcds`r cd ud pesjanc _O_.
Cn tr`t`ijcdte mc cst` p`teneb` g` mc a`s`rsc cd n` `mij-
djstr`ojd mc oertjoejmcs er`ncs ` mesjs mcorcojcdtc y cdnes o`ses rchr`ot`rjes aenes mc ojonehesh`ijm` `seoj`mes e
de ` ictjnprcmdjsened` e pn`si`hrcsjs. Cn predstjoe `
n`rbe pn`ze cs aucde, sj ajcd, cst cd br`d icmjm` mctcr-
ijd`me per nbudes h`otercs oeie cn uicdte mc ojhr`s mc
orc`tjdjd` y pretcjdurj`, n` o`rmjeijep`t` y n` `hcot`ojd
b`strejdtcstjd`n y mcn sjstci` dcrvjese ocdtr`n. Cd p`ojcd-
tcs tr`t`mes oed jdiudesuprcsercs n` jdhcoojd epertudjs-
t` pucmc `sjijsie oedmjojed`r n` supcrvjvcdoj`.
2
0. I`sj @], Gudmcr BB, Ijogcn A@, ct `n. ]gc @icrjo`d Oennc-
bc eh Qgcui`teneby. 0::; orjtcrj` her tgc on`ssjhjo`tjed eh
Ogurb-_tr`uss sydmreic (`nncrbjo br`dunei`tesjs `dm `dbjj-
tjs). @rtgrjtjs Qgcui 0::;< ??60;:=-0;;.
1. Qcjm @FO, G`rrjsed AMR, R`tts Q@, R`tljd _R, IoO`dd
AB, _oett MBJ. Ogurb-_tr`uss sydmreic jd ` mjstrjo gespjt`n.
P F Icm 0::7< :06 10:-11:.
?. _ogd`acn @, Oscrdel C, Ar`ud F, Bress RN. Jdhn`i`tery ocnns
`dm ocnnun`r `otjv`tjed jd tgc newcr rcspjr`tery tr`ot jd Ogurb-
_tr`uss sydmreic. ]ger`x 0:::< 3=6 220-227.
=. Rcogsncr I, B`rpcst`m C, Hnjcr _Q, ct `n. [unied`ry jdhjntr`-
tcs, cesjdepgjnj`, `dm oo`rmjeiyep`tgy hennewjdb oertjoestc-
rejm wjtgmr`w`n jd p`tjcdts wgjg `stgi` rcocjvjdb z`hjrnul`st.
F@I@ 0::7< 12:(8)6 =33-=32.
3. _tjrnjdb QB, Ogudb LH. Nculetrjcdc `dt`bedjst `dm Ogurb-
_tr`uss sydmreic6 tgc sieljdb bud. ]ger`x 0:::< 3=6 783-
788.
8. Rcogsncr IC, Hjdd M, Bud`w`rmcd` M, ct `n. Ogurb-_tr`uss
sydmreic jd p`tjcdts rcocjvjdb iedtcnul`st `s trc`ticdt her
`stgi`. Ogcst 1;;;< 002(?)6 2;7-20?.
AJANJEBQ@H@
]@AN@ JJ. Oeip`r`ojd cdtrc br`dunei`tesjs mc Rcbcdcr (BR) y sdmreic mc Ogurb-_tr`uss (_O_)
@si`
Cesjdehjnj`Gjsterj` mc `ncrbj`X` `rc` supcrjerX` `rc` jdhcrjerBneicrunedchrjtjs@hcot`ojd jdtcstjd`nNcsjedcs outdc`sIededcurjtjs intjpncNcsjedcs eoun`rcs_dtei`s `rtjoun`rcsCdhcricm`m o`rmj`o`p-@DO@o-@DO@
BR
++++++++
+++++++++
+++
_O_
++++
++++++++
+++++
++++++++++
++++
++++
]@AN@ JJJ. Orjtcrjes mc on`sjhjo`ojd mcn sdmreic mcOgurb-_tr`uss (@icrjo`d Oenncbc eh Qgcui`teneby)
@si`
Cesjdehjnj` 4 0;%
Gjsterj` mc `ncrbj`
Iededcurep`t` e penjdcurep`t` per v`sounjtjs
Jdhjntr`mes punied`rcs tr`dsjterjes
@deri`njm`m cd scdes p`r`d`s`ncs
@oiunes mc cesjdhjnes cd rc`s cxtr`v`soun`rcs
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@si`, jdhjntr`mes punied`rcs y cesjdehjnj`
7
Hjb. ?6 ]@O terojo`. Oedmcds`ojd scbicdt`rj` mc NI
oed aredoebr`i` cd su jdtcrjer.
Hjb. =6 Ajepsj` outdc`. Jdhjntr`me jdhn`i`terje jdtcrstj-
oj`n y pcrjv`soun`r.
Hjb. 06 Ncsjd outdc` crjtci`tes` y vjenoc` mc 3 oi mc
mjictre.
Hjb. 16 _jdusjtjs i`xjn`r mcrcog`. [njpes d`s`ncs.
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ufcr mc =1 `es mc cm`m sjd gajtes txj-
oes, o`s`m` y oed mes gjfes s`des, quc tr`a`f cd ud`
ciprcs` mc oedhcoojd tcxtjn y mcsmc g`oc eoge `es cd
ud` hrutcr`. Oedsunt` per mjsdc` prebrcsjv` mcsmc nes ?8
`es.
@dtcocmcdtcs pcrsed`ncs6
]uve teshcrjd` cd n` jdh`doj` y mcsmc cdtedocs prcscdt`
mes e trcs ou`mres o`t`rr`ncs ncvcs, du`ncs, oed tes y cso`-
s` cxpcoter`ojd. @ nes 12 `es mc cm`m tuve ud` dcuie-d` quc rcpjtj ` nes scjs icscs y ud tcrocr cpjsemje ` nes
17 `es. Mcsmc cdtedocs `uicdt`red n` hrcoucdoj` y n`
br`vcm`m mc nes ou`mres o`t`rr`ncs, quc sc `oeip``d mc
sjajn`doj`s y mc uicdte mc n` cxpcoter`ojd. Oed cn mj`b-
dstjoe mc `si`, rcojaj tr`t`ijcdte oed jdiudetcr`pj` y
aredoemjn`t`mercs.
Cxpner`ojd hsjo`6
Aucd cst`me dutrjojed`n< cupdcjo` cd rcpese. @ameicd y
`usount`ojd o`rmj`o` deri`ncs. Cxpner`ojd rcspjr`terj`
oed gjpcron`rjm`m cd n` pcrousjd mc nes o`ipes punied`-
rcs, mjsijduojd bnea`n mcn iuriunne vcsjoun`r y `usoun-t`ojd mc sjajn`doj`s cso`s`s ajn`tcr`ncs.
Cxpner`ojedcs oeipncicdt`rj`s6
Q`mjeneb` terojo`6 gjpcrjdsuhn`ojd ajn`tcr`n (hjbs. 0` y a).
]eiebr`h` `xj`n oeipur`tjz`m` oed cdhjsci` y aunn`sajn`tcr`ncs, sjd jibcdcs subcrcdtcs mc aredqujcot`sj`s
(hjb. 1).
Cxpner`ojd hudojed`n punied`r6 HXO 0.:1; in (8?%),HCX0 :1; in (?7%), HCX0/HXO =7%, XQ 3.;1; in
(?=7%), ]NO 2.;?; in (08?%), ]NOE =2%, ]NOE/X@
33%. Br`vc tr`sterde eastruotjve oed br`d `tr`p`ijcdte
`rce y mcsocdse br`vc mc n` mjhusjd mc OE quc de sc
oerrjbc, cd rcn`ojd n venuicd nvcen`r. [ruca` aredoemj-
n`t`mer` dcb`tjv`.
@dnjsjs mc s`dbrc6 gciebr`i` y pcrhjn ajequijoe der-i`ncs. Jdiudebneaunjd`s y suaon`scs mc JbB deri`ncs.
[retcjdebr`i` oed `nh`0 mcn 1,1%. @nh`0-`dtjtrjpsjd`(@@]) 08 ib/mn (r`dbe deri`n, 00? ` 10?). Hcdetjpe
@@], geieojbete oed `ncnes mumeses.
Bcdetjpe @@]6 n` scoucdoj`ojd mciestr quc sc tr`t`a`mc ud geieojbete oed mes `ncnes jmdtjoes, oed mes iut`-
ojedcs pudtu`ncs6 ud` sustjtuojd mc B@] per B]] cd cn
cxd JJJ cd pesjojd 138, ne quc m` nub`r ` ud o`iaje mc
@sp per X`n, y ud` scbudm` sustjtuojd mc OOO per O@O
cd cn cxd X cd pesjojd ?:0, ne quc o`iaj` ud` [re per
Gjs cd mjog` pesjojd ?:00 (hjb. ?).
Cvenuojd6 _c jdjoj tr`t`ijcdte sustjtutjve oed `nh`0-`dtj-
trjpsjd`, jdtr`vcdes`, o`m` 10 m`s, act`bedjst`s mc n`rb`mur`ojd, oertjoejmcs jdg`n`mes y `dtjajtjoes cd n`s `bumjz`-
ojedcs. _c i`dtjcdc oed ud` hudojd rcspjr`terj` cst`anc
mur`dtc nes ntjies trcs `es.
Mjsousjd6
N` cdhcri` prcscdt` ud ou`mre ondjoe mc mjsdc` oeie sd-
tei` meijd`dtc, fudte ` ondjo` mc aredqujtjs ordjo` oed
tes y cxpcoter`ojd mj`rj` c jdhcoojedcs rcspjr`terj`s. Nes
:
=.1. Cdhjsci` cd iufcr fevcdde hui`mer`
Q. XJM@N, O. MC N@ QEV@, Q. F@QM
_crvjojes mc Dcuieneb` y Ajequijo`.Gespjt`n X`nn mGcared. A`rocned`.
I
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7/29/2019 3 NEUMO4 (v3)
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m`tes mc n` cxpner`ojd hsjo` oed mjsijduojd mcn iuriu-
nne vcsjoun`r c gjpcron`rjm`m cd n` pcrousjd mc nes o`ipes
punied`rcs erjcdt`d g`oj` cn mj`bdstjoe mc cdhjsci` pun-
ied`r, quc sc oedhjri` per cn cx`icd r`mjenbjoe y n`
cxpner`ojd hudojed`n rcspjr`terj`. Cstes m`tes iucstr`d nes
sjbdes tpjoes mcn `tr`p`ijcdte `rce, gjpcr`jrc`ojd mco`ipes punied`rcs oed gerjzedt`njm`m oest`n y mcsocdse
mj`hr`bitjoe, ud p`trd eastruotjve br`vc oed ud on`re
jdorcicdte mcn venuicd rcsjmu`n y v`nercs mjsijdujmes mc
n` o`p`ojm`m mc mjhusjd. Cst` heri` mc prcscdt`ojd `p`rc-
oc g`st` cd ud 3;% mc nes o`ses mc cdhjsci` per mhjojt mc
@@], per ne quc mcac pcds`rsc cst` ctjeneb` searc teme cd
pcrsed`s fvcdcs de hui`mer`s. Cn mcsocdse mc n` a`dm`
`nh`0 mcn pretcjdebr`i` m` ud` sespcog` jdjoj`n y pestcrjer-
icdtc n` mctcrijd`ojd mc nes djvcncs a`fes mc n` cdzji`
`nh`0-`dtjtrjpsjd` oedhjri` n` o`us` mcn cdhjsci`. Jdjoj`n-
icdtc sc oedsjmcr oeie hcdetjpe geieojbete [jVV m`me
quc n` ducv` v`rj`dtc quc `qu mcsorjajies prcscdt` cd n`
todjo` mc jdiudecncotrehercsjs ud` ijbr`ojd prxji` n`quc tjcdc n` v`rj`dtc mchjojt`rj` [jVV. _jd cia`rbe, cn `dnj-
sjs iencoun`r mcn bcd mc n` @@] rc`njz`me pestcrjericdtc
cvjmcdoj n` ducv` v`rj`dtc mchjojt`rj` cd cst`me geieojbe-
te oed mes iut`ojedcs pudtu`ncs, ud` cd cn cxd JJJ y etr` cd
cn cxd X, iut`ojd quc de cst`a` mcsorjt` prcvj`icdtc, per
ne quc huc mcdeijd`m` Z per su ievjnjm`m cncotrehertjo` y
A`rocned` per scr n` ojum`m medmc huc mcsouajcrt` cst`
ducv` v`rj`dtc ([j Za`rocned`-Za`rocned`)0. N` tr`dsijsjd
gcrcmjt`rj` mcn `ncne [j Za`rocned` sc mciestr icmj`dtc cn
cstumje h`ijnj`r.
Cn mhjojt mc nh`0-`dtjtrjpsjd` cs ud` cdhcricm`m oedbdjt`,
mc gcrcdoj` `utesijo` oemeijd`dtc, quc oedmjojed` udrjcsbe cncv`me mc cdhjsci` punied`r cd muntes fvcdcs. Cn
bcd, neo`njz`me cd cn oreiesei` 0=, prcscdt` ud br`d penj-
ierhjsie, mc ieme quc icmj`dtc n` todjo` mcn jsecncotre-
cdhequc sc g`d jmcdtjhjo`me is mc 23 v`rj`dtcs mc n` cdzj-
i`, cd su i`yer` erjbjd`m`s cd o`iajes cd n` scoucdoj` mc
`ijdeojmes mcajmes iut`ojedcs mcn bcd quc n`s oemjhjo`1.
Cn hcdetjpe rcsunt` mc n` cxprcsjd jdmcpcdmjcdtc mc nes mes
`ncnes y sc cxprcs` oeie [j (jdgjajmer mc n`s pretc`s`s)
scbujme mc ud`s nctr`s i`ysoun`s quc oerrcspedmcd ` nes
`ncnes y sc `sjbd`d scbd n` ievjnjm`m cncotrehertjo`.
Ondjo`icdtc, n`s v`rj`dtcs mc @@] pucmcd on`sjhjo`rsc
cd trcs brupes (deri`ncs, mchjojt`rj`s y dun`s) sj sc tjcdccd oucdt` n` oedocdtr`ojd mc @@] cd sucre y su o`p`oj-
m`m hudojed`n. N`s v`rj`dtcs deri`ncs is hrcoucdtcs
pcrtcdcocd ` n` h`ijnj` mc `ncnes [j I. N`s v`rj`dtcs
mchjojt`rj`s i`yerjt`rj`s sed n`s rcn`ojed`m`s oed cn ncne
[j _ y searc teme oed cn [j V. N` br`d i`yer` mc nes
mhjojt br`vcs mc @@] njb`mes ` cdhjsci` sed geieojbe-
tes [jVV. G`y etr`s v`rj`dtcs mchjojt`rj`s iuoge icdes
hrcoucdtcs pcre quc oeipert`d t`iajd ud rjcsbe cncv`-
me mc cdhjsci`. Qcojcdtcicdtc ducstre brupe g` mcsorj-
te n` v`rj`dtc Za`rocned` cd cst` h`ijnj` tr`s cn cstumje mcn
o`se quc prcscdt`ies. N`s v`rj`dtcs dun`s sed r`r`s y sc
o`r`otcrjz`d per prcscdt`r oedocdtr`ojedcs mc @@] jdmc-
tcot`ancs.
Cn mcsouarjijcdte mc ud` `seoj`ojd cdtrc cn mhjojt gcrc-mjt`rje mc @@] y cdhjsci` punied`r g` sjme hudm`icdt`n
cd cn mcs`rrenne mc n` tcer` mc n`s pretc`s`s-`dtjpretc`s`s
cd n` p`tebdcsjs mcn cdhjsci`, per n` ou`n, ou`dme cdzj-
i`s pretcentjo`s oeie n` cn`st`s` mc nes ncuoeojtes sed
njacr`m`s cd nes puniedcs, jdgjajmercs mc n`s pretc`s`s, mc
n`s ou`ncs n` @@] rcprcscdt` cn :;%, prcvjcdcd n` mcs-
truoojd mcn p`rdquji` punied`r. Ou`dme nes jdgjajme-
rcs mc n`s pretc`s`s sc cdoucdtr`d cd djvcncs jdhcrjercs `
nes mc n`s pretc`s`s, st`s preveo`d mcstruoojd punied`r
quc pestcrjericdtc nncv` `n cdhjsci` punied`r?-3.
Mc nes rcsunt`mes mcrjv`mes mc cstumjes cpjmcijenbjoes
pean`ojed`ncs sc oedonuyc quc cn mhjojt mc @@] cs ud`cdhcricm`m jdhr`mj`bdestjo`m` cd n` i`yer` mc nes p`scs
eoojmcdt`ncs jdonujme Csp``8. Cn mj`bdstjoe mc sespcog`
sc hudm`icdt` cd n` `p`rjojd mc ud cdhjsci` punied`r cd
ud` pcrsed` fevcd y oed gjsterj` h`ijnj`r mc cdhcricm`m rcs-
pjr`terj`. Cd cstes o`ses, n` oedhjri`ojd sc sucnc eatcdcr
oed n` mctcrijd`ojd mc n`s oedocdtr`ojedcs mc @@] srjo`s,
deri`nicdtc icmj`dtc dchcneictr`2, `udquc cst` todjo`
de sjciprc cs hojnicdtc mjspedjanc, per ne quc n` mctcrij-
d`ojd mc n` a`dm` `nh`0 mcn pretcjdebr`i` cs ud iteme
scdojnne y `n `no`doc mc ou`nqujcr n`aer`terje quc pucmc scr
iuy tjn cd cn orja`me mcn mhjojt mc @@] cd p`ojcdtcs oed
cdhcricm`mcs rcspjr`terj`s ordjo`s7.
Cd n` `otu`njm`m, cn mj`bdstjoe mc n`aer`terje sc rc`njz`
icmj`dtc n` oeiajd`ojd mc n` mctcrijd`ojd ou`dtjt`tjv`
mc n` @@] y mcn hcdetjpe icmj`dtc cdhequc jsecnotrjoe.
Ou`dme cst` ntji` de preperojed` suhjojcdtc jdheri`ojd e
de g`y ud` aucd` oerrcn`ojd cdtrc cn hcdetjpe y nes djvcncs
mc @@], cn mj`bdstjoe mc mhjojt oedbdjte sc oedhjri`
icmj`dtc n` mctcrijd`ojd mcn bcdetjpe mc n` @@]:.
N` EI_ rcoeijcdm` quc temes nes p`ojcdtcs oed C[EO y
t`iajd nes `muntes y `mencsocdtcs oed `si` mcacd seic-
tcrsc ` ud orja`me ud` vcz `n icdes cd su vjm` p`r` cn mhj-
ojt mc @@], us`dme ud tcst ou`dtjt`tjve (per cfcipne jdiu-
decncotrehercsjs). ]r`s cn mj`bdstjoe mc ud mhjojt mc @@]cs jipert`dtc rc`njz`r cn cstumje hcdetpjoe mc nes h`ijnj`rcs
oeds`dbudces. Oed hrcoucdoj` pemcies cdoedtr`r ducves
o`ses [jVV cd h`sc prcsjdteitjo` y `s jdst`ur`r icmjm`s
prehjnotjo`s y rc`njz`r ud oedscfe bcdtjoe.
N` iert`njm`m mc nes p`ojcdtcs oed mhjojt mc @@] cst
dtji`icdtc rcn`ojed`m` oed cn HCX06 n` supcrvjvcdoj`
icmj` mc nes quc tjcdcd ud HCX0 > 13% cs mc 8,? `es,
ijcdtr`s quc oed ud HCX0 cdtrc 13% y =:% cs mc 0;,3
Cdhjsci` cd iufcr fevcd de hui`mer`
0;
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7/29/2019 3 NEUMO4 (v3)
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`es. Cn t`a`oe cs cn cncicdte on`vc cd n` gjsterj` d`tur`n
mc nes p`ojcdtcs oed mhjojt mc @@]. Cn mconjvc mcn HCX0`s oeie n` iert`njm`m cstd mjrcot`icdtc jdhnujmes per n`
o`dtjm`m mc t`a`oe oedsuijme. Nes p`ojcdtcs quc mcf`d mc
hui`r oedsjbucd rcmuojr n` prmjm` mc HCX0, sjd cia`rbe,
cst` o`m` de `no`dz` n`s ojhr`s deri`ncs cdoedtr`m`s cdpcrsed`s de mchjojt`rj`s0;.
N`s icmjm`s prehjnotjo`s p`r` cvjt`r n` prebrcsjd mcn cdhj-
sci` v`d cdo`ijd`m`s cvjt`r jrrjt`dtcs rcspjr`terjes oeie
cn t`a`oe y nes oedt`ijd`dtcs n`aer`ncs, y n tr`t`ijcdte prc-
oez y n` prcvcdojd mc n`s jdhcoojedcs rcspjr`terj`s.
Cd ou`dte `n tr`t`ijcdte, mcsmc hjd`ncs mc 0:72 sc oucdt`
oed ud` prcp`r`ojd purjhjo`m` mc `nh`0-`dtjtrjpsjd` quc
pucmc `mijdjstr`rsc ` n`s pcrsed`s `hcot`m`s. ]r`s su `mij-
djstr`ojd sc `no`dz`d y i`dtjcdcd djvcncs is deri`njz`-
mes y prcsuijancicdtc pretcotercs. _c pjcds` quc mjog`
tcr`putjo` pucmc r`ncdtjz`r n` prebrcsjd mc n` cdhcricm`m.Cxjstc ud rcbjstre csp`en quc g` oedscdsu`me nes orjtcrjes
quc mcacd ouipnjr nes cdhcries p`r` jdjoj`r cn tr`t`ijcdte
`uicdt`tjve oed @@]6 djvcncs mc @@] jdhcrjercs `n ?3% mc
ne deri`n, hcdetjpes geieojbetes [jVV, [jV dune [j dune-
dune u etr`s v`rj`dtcs mchjojt`rj`s, hudojd punied`r `der-
i`n y de hui`mercs8. _c oeicdz mijdjstrdmen` cd mesjs
sci`d`ncs senuojd jdtr`vcdes`, udquc sc cxtjcdmc su utj-
njz`ojd ` p`ut`s icdsu`ncs e o`m` trcs sci`d`s, ` mesjs mc1=; ib/lb00,01. @otu`nicdtc sc cst cds`y`dme cn use per
v` jdg`n`m` mc @@] eatcdjm` per rcoeiajd`ojd bcdtjo` y
iemjhjo`m` cd su pesjojd ?37 (Ict per X`n) oed ne quc sc
oedsjbuc ud` `oojd is rpjm` hrcdtc ` n` cn`st`s` y rcsjs-
tcdoj` hrcdtc ` n` exjm`ojd0?.
Cn tr`spn`dtc punied`r, y` sc` udj e ajpunied`r, pucmc scr
ud` `ntcrd`tjv` cd p`ojcdtcs oed mhjojt mc @@] cd h`sc
cvenuojed`m`. Mcac scr jdmjo`me ou`dme cn HCX0 mcsojcd-
mc per mca`fe mcn 03% mc su v`ner tcrjoe. Cn p`pcn mcn tr`-
t`ijcdte `uicdt`mer mcspus mcn tr`spn`dtc cs jdojcrte y
sc dcocsjt`d is cstumjes p`r` on`r`rne. Mc tem`s heri`s,
tcdjcdme cd oucdt` n` supcrvjvcdoj` `otu`n pestr`spn`dtcmc cstes p`ojcdtcs, cs peoe prea`anc quc n` o`rcdoj` mc
@@] `hcotc n` cvenuojd mcn jdfcrte.
00
0. F`rm Q, Qemrbucz H, Ijr`vjtnncs I, ct n. Jmcdtjhjo`tjed `dm
iencoun`r og`r`otcrjz`tjed eh tgc dcw `npg`-0-`dtjtrypsjd
mchjojcdt `nncnc [J Z a`rocned` (@sp1384X`n `dm
[re?:04Gjs). Iut`tjeds jd arjch de. 02=. Ednjdc. Gui
Iut`t 0::7< 01(?)6 10?.
1. Oryst`n QB, Ar`dtny IN, Guaa`rm QO, ct `n. ]gc `npg` 0-
`dtjtrypsjd bcdc `dm jts iut`tjeds. Onjdjo`n oedscqucdocs
`dm str`tcbjcs her tgcr`py. Ogcst 0:7:< :36 0:8-1;7.
?. Crjlssed _. _tumjcs jd `npg` 0-`dtjtrypsjd mchjojcdoy. @ot`
Icm _o`dm _uppn 0:83< =?16 0-73.
=. B`mcl FC, [`ogt CQ. ]gc pretc`sc-`dtjpretc`sc a`n`doc wjtgjd
tgc gui`d nudb6 jipnjo`tjeds her tgc p`tgebcdcsjs eh cipgy-
sci`. Nudb 0::;< 087 _uppn6 331-38=.
3. _teolncy Q@. Dcutrepgjns `dm pretc`sc/`dtjpretc`sc jia`-n`doc. @i F Qcspjr Orjt O`rc Icm 0:::< 08;6 _=:-_31.
8. Ijr`vjtnncs I, Xjm`n Q, A`rres-]jzed FO, Aust`i`dtc @,
Csp`` [[, O`s`s H, I`rtdcz I], Csoumcre O, F`rm Q. Cst`-
me `otu`n mcn tr`t`ijcdte sustjtutjve cd cn cdhjsci` oedbdj-
te per mhjojt mc `nh`-0-`dtjtrjpsjd`. Jdheric mcn Qcbjstre
D`ojed`n. @rog Aredoedcuien 0:::< ?36 ==8-=3=.
2. Xjm`n Q, Ijr`vjtnncs I, F`rm Q, ]errcnn` I, Qemrbucz-Hr`s
H, Ier`n [, X`qu F. Cstumje mc n` hrcoucdoj` mc nes mjhcrcd-
tcs hcdetjpes mc n` `nh`-0-`dtjtrjpsjd` cd ud` pean`ojd mc
A`rocned`. Icm Onjd (A`ro) 0::8< 0;26 100-10=.
7. Ijr`vjtnncs I, F`rm Q, Qemrbucz-Hr`s H, ]errcnn` I, [cnc-
br M, Xjm`n Q. Stjnjm`m mc n` ou`dtjhjo`ojd mc n` a`dm` `nh`-
0-`dtjtrjpsjd` mcn pretcjdebr`i` srjoe cd cn orja`me mcn mhj-
ojt mc `nh`-0-`dtjtrjpsjd`. @rog Aredoedcuien 0::7< ?=6 3?8-
3=;.
:. O`ipacnn CF. @npg`0-`dtjtrypsjd mchjojcdoy6 jdojmcdoc
`dm mctcotjed prebr`i. Qcspjr Icm 1;;;< := _uppn O6
_07-_10.
0;. _ccrsgeni D, Lel-Fcdscd @. _urvjv`n jd rcn`tjed te nudb
hudotjed `dm sieljdb ocss`tjed jd p`tjcdts wjtg scvcrc gcrc-
mjt`ry `npg` 0-`dtjtrypsjd mchjojcdoy. @i F Qcspjr Orjt O`rc
Icm 0::3< 0306 ?8:-?2?.
00. Rcwcrs IM, O`sen`re I@, _cnncrs _C, ct `n. Qcpn`ocicdt
tgcr`py her `npg` 0-`dtjtrypsjd mchjojcdoy `sseoj`tcm wjtgcipgysci`. D Cdbn F Icm 0:72< ?086 0;33-0;81.
01. Xjm`n Q, Ijr`vjtnncs I, Mc Br`oj` W, B`nncbe A, Iercnn H.
]r`t`ijcdte sustjtutjve mcn cdhjsci` per mhjojt mc `nh`-0-
`dtjtrjpsjd`. Icm Onjd (A`ro) 0::0< :86 07;-071.
0?. [`stcur I, Lceb`d I, Cnaerd _, I`rtd _, Auoljdbg`i _,
Cmb`r F, Ajnted M. _`hcty `dm tencr`ajnjty eh heur `socdmjdb
sjdbnc mescs eh tr`dsbcdjo sgccp mcrjvcm gui`d `npg`-0-
`dtjtrypsjd (tb-g@@]) mijdjstcrcm ay dcaunjscr te p`tjcdts
wjtg oystjo hjaresjs (OH). @i F Qcspjr Orjt O`rc Icm 0:::
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