834 Seafood in pregnancy and mercurylevels in umbilical cord bloodReni Soon1, Timothy Dye1, Nicholas Ralston2, Marla Berry3,Lynnae Sauvage1

1University of Hawaii, Obstetrics & Gynecology, Honolulu, HI, 2Universityof North Dakota, Energy & Environmental Research Center, Grand Forks,ND, 3University of Hawaii, Cell & Molecular Biology, Honolulu, HIOBJECTIVE: The purpose of this study was to examine the influence ofmaternal fish consumption during pregnancy on umbilical cord mer-cury (Hg) concentrations in a multiethnic cohort of US women.STUDY DESIGN: This was a secondary analysis of a prospective cohortpilot study examining antenatal fish consumption and neonatal out-comes in Hawaii. The first 100 women who met eligibility criteria andconsented were enrolled. After delivery umbilical cord blood was col-lected and women completed a dietary survey of their last month ofpregnancy.RESULTS: 86% of women reported eating fish during the previousmonth, with 9% eating more than the recommended limit of 12 oz perweek. 75% of Filipina ate fish, which was significantly less than non-Filipina (p�.05). Women of most ethnicities consumed similar quan-tities of fish, with the exception of Japanese women, who consumedsignificantly less fish than non-Japanese, and Pacific Islander women,who consumed significantly more. Fish consumption varied signifi-cantly by income status, with 30% of poor women averaging morethan 12 oz per week. Fish consumption did not vary by women’s age,or education. 44% of all women had 5�g Hg/L or more. Filipina weresignificantly less likely to have elevated Hg levels when compared withnon-Filipina (�.05). Mercury levels did not vary by other demo-graphic characteristics. Women who reported eating more than 12 ozof fish per week were significantly more likely to have 5�g Hg/L ormore, but mean Hg levels were not significantly higher (6.1�3.3 v5.0�3.7). The odds ratio for elevated Hg, however, was significant

among fish-consumers compared with non-consumers (5.7; 95%confidence interval: 1.2, 27.1).CONCLUSION: Despite variation by ethnicity and income status in fishconsumption during pregnancy, there exists a strong correlation be-tween fish consumption and mercury levels. Almost half of thewomen in this study had elevated mercury levels. This project wassupported by grants NCRR U54RR026136 and NIMHDU54MD007584 from the National Institutes of Health.

835 Comparative study of two methods of TDAPvaccine education in the African American populationin the immediate post-partum periodWilkens Mondesir1, Tasscia Williams1, Linet Ochweri1, JoshuaFogel1, pqaVinette Greenland1, Maggie Tetrokalashvilli1, Chaur-Dong Hsu1

1Nassau University Medical Center, Obstetrics and Gynecology, EastMeadow, NYOBJECTIVE: To compare among African Americans in the immediatepost-partum period receipt of the TDAP vaccine using the CDCTDAP pamphlet versus a culturally tailored video.STUDY DESIGN: We selected 101 African Americans from those whowere previously seen in hospital and who had received the standardhospital educational packet that included the CDC TDAP vaccinepamphlet (non-tailored group). We created a culturally tailored videofor encouraging use of the TDAP vaccine for African Americans in-corporating psychological principles from the Theory of Planned Be-havior. This tailored intervention was prospectively provided to 50African Americans. These two intervention groups were comparedusing univariate and multivariate analyses for receipt of the TDAPvaccine.RESULTS: Using the Pearson chi square test, those in the tailored in-tervention group had a significantly (p�0.001) greater percentage of76.0% (38/50) receiving the TDAP vaccine as compared to the 28.7%(29/101) in the non-tailored group. Using logistic regression analysesthe tailored group had odds ratios of almost 12 for greater odds forreceiving the TDAP vaccine (OR: 11.97, 95% CI: 4.43, 32.34). None ofthe other possibly relevant variables were statistically significant.CONCLUSION: The use of a culturally tailored video as a method ofeducation about the TDAP vaccine has a significantly greater potentialimpact than a standard educational approach for African Americansreceiving the TDAP vaccine in the immediate post-partum period.We recommend using such video interventions for encouraging Af-rican Americans to use the TDAP vaccine in the immediate post-partum period.

836 Limiting exposure of a select group of fetuses to intra-amniotic infection (IAI) may improve short-term neonataloutcome in pregnancies complicated by PPROMKaren Archabald1, Irina Buhimschi1, Mert Bahtiyar1, AntonetteDulay1, Sonya Abdel-Razeq1, Christian Pettker1, HeatherLipkind1, John Hardy1, Megan McCarthy1, Guomao Zhao1, VineetBhandari2, Catalin Buhimschi1

1Yale University, Ob/Gyn & Reprod. Sci., New Haven, CT, 2Yale University,Pediatric Neonatology, New Haven, CTOBJECTIVE: In PPROM, the host response to infection may cause in-flammation that could act synergistically with microbial insult to in-duce fetal damage. The key benefit of a prompt delivery should be

Sensitivity analysis: cost per case for doula care inactive labor

Obstetrical & neonatal outcomes (per 47,000 livebirths)

Fish consumption and mercury concentration incord blood

*p�.05.

www.AJOG.org Clinical Ob, Epidemiology, ID, Intrapartum Fetal, Operative Ob, Med-Surg-Diseases, Ob Quality & Safety, Public & Global Health Poster Session V

Supplement to JANUARY 2013 American Journal of Obstetrics & Gynecology S349