4 –respiratory system learning component lung

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Learning Module 4 – Respiratory System Learning Component 3 Lung 1

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Page 1: 4 –Respiratory System Learning Component Lung

Learning Module 4 – Respiratory SystemLearning Component 3 ‐ Lung

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Normal lung showing cross sections of parabronchi

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Normal lung showing parabronchi, also termed tertiary bronchi (A ‐C).Blood in parabronchi (B and D) is a common finding and not a lesion.A few, scattered, focal collections of cartilage (D) are normal in broiler lungs.

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Inhaled toxic gas injury.Fibrin accumulation is accumulating in parabronchi (B – D) and there is a histiocytic response by pneumocytes (B).

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Lung – Laryngotracheitis

Note necrosis (A) and synctial cells with I/N inclusions (B‐D).

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Lymphocytic and proliferative pneumoniaSuggestive of a viral infection – suspect infectious bronchitis virus.

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Lung – Giant Cell Pneumonia

Probable Viral Etiology

Note absence of inclusion in the synctial cell nuclei.

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Acute fibrinoheterophilic pneumonia.Early bacteria infection – consider ORT or acute mycoplasma infection.

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Mycoplasma pneumonia with lymphofollicular response within a diffuse fibrinoheterophilic  pneumonia

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Bacterial pneumonia – fibrinoheterophilic and necrotizing with intralesional bacteria.Requires culture and identification for etiologic diagnosis.Intralesional bacteria are shown in D.Case was due to Pasteurella

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Bacterial pneumonia with fibrinoheterophilic response, caseous necrosis and granuloma formation with giant cells.E. Coli was the etiology, but requires isolation and identification for diagnosis as to etiology.

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Bacterial pneumonia with caseous necrosis and intralesional bacteria is typical of colibacillosis.

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AspergillosisMycotic pneumonia with multiple areas of caseous necrosis and intralesional fungi.D is a GMS stain.

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Mycotic pneumonia with granulomas and numerous giant cells.Outlines of hyphae are seen in C and within the giant cell in D.

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Lung – Sarcocystis falcutala – protozoal parasite in capillaries.

Note the disorganized pattern of erythrocytes in the blood capillaries.

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Primary carcinomaA – D show an adenocarcinoma arising from bronchial epithelial cells as well‐illustrated in D.

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Marek’s diseaseShown is the extensive infiltration of interstitial tissue and replacement of the capillary bed by neoplastic lymphoid cells.

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Histiocytic pneumoniaA proliferation of histiocytes is replacing the capillary bed in this lung from a broiler breeder.Cause is unkonwn.

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