SRWS1

@Hospital Care Research Unit

2

3

What

is known

https://upload.wikimedia.org/wikipedia/commons/b/b5/Rubin2.jpg3

EBM

4Users' Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice, 3rd G Guyatt 2015

5

What is not

known

https://upload.wikimedia.org/wikipedia/commons/b/b5/Rubin2.jpg5

SR

6

Step 2:

8

Ground rulesBLAMESHAME

9

https://pixabay.com/ja/%E6%80%92%E3%81%A3%E3%81%9F%E7%94%B7-%E3%83%9D%E3%82%A4%E3%83%B3%E3%83%88-%E6%8C%87-%E3%82%A4%E3%83%B3%E3%83%89-%E6%80%92%E3%81%A3%E3%81%A6-%E7%94%B7%E6%80%A7-%E6%89%8B-%E6%80%92%E3%82%8A-%E9%9D%9E%E9%9B%A3-274175/

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1012

rPHS index

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13 2000

WS14, 2015

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()

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19WS

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SRWSSR20

WS21

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20144823

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https://pixabay.com/ja/%E6%80%9D%E8%80%83-%E5%9B%B3-%E4%BA%BA-%E9%9D%92-%E3%82%B9%E3%83%86%E3%82%A3%E3%83%83%E3%82%AF%E5%9B%B3-%E8%80%83%E6%85%AE%E3%81%97%E3%81%BE%E3%81%99-%E3%82%B3%E3%83%B3%E3%82%BB%E3%83%97%E3%83%88-%E6%96%87%E5%AD%97-25548/

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(47)29

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:

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37

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SRMA39(Risk of bias)

(=meta-analysis)

239

40

41(%)21733733.3 14311214.3 306981343.3

prostate specific antigen

42

Ultrasonography for confirmation of gastric tube placement.Tsujimoto H, et al.Cochrane protocol published

43

44

45

http://www.freestockphotos.biz/stockphoto/172045

SR//

47

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RCTMeta-epidemiological study48

49

50

51

52

52

RCT53

54

http://www.slideshare.net/enango/why-gradecpg150707

55Cochrane handbook for Systematic Reviews of Interventions

55

56

57

58

http://www.slideshare.net/enango/why-gradecpg150707

Systematic review(SR)111SR

PLoS MED, 2010 SR

59

The Lancet, 2011

61

62

63

64

Intensive statin therapyLancet, 2010

65

1.0 (0.98-1.02)BMJ, 2013

66

67

Body of evidence

A RCT

BC

DIFRCT68

69

70RCTCVDQOLstudystudystudystudy

71RCTCVDQOLstudystudystudystudy

72

72

73

SR

74

75

SR76

Aihara, 2015

GRADE77

78

79

Meta-epidemiological study80

Meta-epidemiological studyMeta-epidemiological study

81Epidemiol Health, 2014

Meta-epidemiological study P: IF10SR

I: SR

C: SR

O: 82

Meta-epidemiological studySR83P: IF10SR

I: SR

C: SR

O: P: RCT

I:

C:

O:

84

85

SRMeta-epi

86

87

reviewer

senior investigator

SR

88

RCTMeta-epidemiological study

89

90

91

IF 6.2)

92

93RQOK6

94

952/

SRWS1

QI SLE, HD SR

96

96

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Hospital Care Research Unit//

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SRWS@100

101

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108

https://www.youtube.com/watch?v=l_w582sisGY108

109

https://pixabay.com/static/uploads/photo/2015/11/06/12/38/juggle-1027150_960_720.jpg109

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111

()

https://upload.wikimedia.org/wikipedia/commons/a/a3/Handshake_(Workshop_Cologne_'06).jpeg111

SRWS@

112

: scarecity

113

114

https://pixabay.com/static/uploads/photo/2014/09/12/22/28/baby-443393_960_720.jpg114

1

115

Take Home Message 116

117

Hospital Care Research Unit//

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RCT

119

/120

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RCTRCTPI123

RCTRCT

/123

VS VS HPV VS

124

RCTRCT

/124

PI125

()Cochrane review

RCT

126

127

127

128

ect.UpToDateCochrane LibraryRQClinical QueriesGoogle scholarClinical Key

http://www.uptodate.com/contents/searchhttp://www.cochranelibrary.com/http://www.ncbi.nlm.nih.gov/pubmed/clinicalhttps://scholar.google.co.jp/https://www.clinicalkey.jphttp://login.jamas.or.jp/128

129Cochrane LibraryRQ

Medline via PubmedClinical QueriesMedline via Ovid 129

130

http://www.sunshinecoastdaily.com.au/news/view-from-the-bwindi-forest-travel/1435909/

130

P: I: C: O: 131PICO

131

Cochrane Library132

Advanced searchIP

133

133

134

134

135

135

PICOPIAND

136

PICOPIkey word

137

word

blood culturesepsisORPPIPPIOR138

138

Cochrane review

2RCT

139

Cochrane Library140

Advanced searchCENTRAL

141

141

142CENTRALCENTRALCochrane Central Register of Controlled Trials

TrialsCENTRALCochrane Central Register of Controlled Trials142

143

http://www.sunshinecoastdaily.com.au/news/view-from-the-bwindi-forest-travel/1435909/143

RCT

144

145

Cochrane Handbook for Systematic Reviews of Interventions Higgins JPT 2011

145

srws.hcru@gmail.com146

147

148

30

24

WS

RQ

149

RQI+C=PECPPOPO150

3PO

PICO28Pspecific151

4Be specific!

DICrTMFOY

152

5 FAQQ

A WSOK153

6 FAQQ

A WS154

()155

*07/16/96*##

134

1572015pp.2-3

157

Repetitive Facilitative Exercise; RFE

158

158

1

212

31100

159

159

160

160

161

161

162

162

RCT2015BRCT

163

163

164

PICO

166

Arm contractures or painPre-existing arm impairmentPerceptual, apraxic, or cognitive deficits

167

168

169

170

171

1. Activities of Daily LivingFunctional Independent Measure

2. Fugl-Meyer Assessment3. 4. Complex regional pain syndrome5.

2016.2.19

MEDLINE via PubMed The Cochrane Central Register of Controlled Trials the World Health Organization International Clinical Trials Platform Search Portal ClinicalTrials.gov

172

PubMed

173#1Search Cerebrovascular disorders [MH]299784#2Search Basal ganglia cerebrovascular disease [MH]407#3Search Brain ischemia [MH]87627#4Search Carotid artery diseases [MH]40463#5Search Intracranial arterial diseases [MH]51457#6Search Intracranial arteriovenous malformations [MH]7533#7Search Intracranial thrombosis [MH]5070#8Search Intracranial embolism [MH]4510#9Search Intracranial hemorrhages [MH]59448#10Search Stroke [MH]97262#11Search Brain infarction [MH]31258#12Search stroke lacunar2997#13Search vasospasm intracranial2555#14Search vertebral artery dissection1316#15Search (#1 OR #2 OR #3 OR #4 OR #5 OR #6 OR #7 OR #8 OR #9 OR #10 OR #11 OR #12 OR #13 OR #14)300258#16Search Stroke [TW]208213#17Search Poststroke [TW]3394#18Search Post-stroke [TW]5148

PubMed

174#19Search Cerebrovasc* [TW]117090#20Search Brain vasc* [TW]945#21Search Cerebral vasc* [TW]7213#22Search Cva* [TW]3285#23Search Apoplex* [TW]2765#24Search SAH [TW]8073#25Search (#16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22 OR #23 OR #24)310677#26Search Brain* [TW]1154592#27Search Cerebr* [TW]614487#28Search Cerebell* [TW]108668#29Search Intracran* [TW]135573#30Search Intracranial* [TW]135436#31Search Subarachnoid* [TW]35466#32Search (#26 OR #27 OR #28 OR #29 OR #30 OR #31)1570767#33Search Hemorrhage* [TW]242450#34Search Haemorrhage* [TW]32067#35Search Haemoatoma* [TW]2#36Search Hematoma* [TW]49986

PubMed

175#37Search Bleed* [TW]160538#38Search (#33 OR #34 OR #35 OR #36 OR #37)230681#39Search Ischemi* [TW]306548#40Search Infarct* [TW]281969#41Search (thrombo* [TW] AND emboli* [TW])20158#42Search Occulus* [TW]90#43Search (#39 OR #40 OR #41 OR #42)541583#44Search Hemiplegia [MH]10780#45Search Paresis [MH]6643#46Search Hemipleg* [TW]15436#47Search Hemipar* [TW]10889#48Search Paresis* [TW]13544#49Search Paretic* [TW]2412#50Search (#44 OR #45 OR #46 OR #47 OR #48 OR #49)37455#51Search (#15 OR #25 OR #32 OR #38 OR #43 OR #50)2281655#52Search repetitive facilitative exercise [TW]5#53Search facilitative exercise [TW]6#54Search RFE [TW]328

PubMed

176#55Search repetitive facilitation [TW]3#56Search Neurofacilitation [TW]8#57Search intensive repetition [TW]6#58Search repetitive facilitative [TW]0#59Search kawahira [tiab]0#60Search (#52 OR #53 OR #54 OR #55 OR #56 OR #57 OR #58 OR #59)342#61Search (#51 AND #60)49

177((((/TH) or (/TH)) and (PT=)) and (((/AL) or (/AL) and (PT=)) or ((/AL) and (PT=)) or ((/AL) and (PT=)))) and ((((RD=) or (RD=) or (RD=)) and (PT=)) or ((RD=) and (PT=)))

2

178

179

//

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I2 (I2 > 50%)I2Cochrane Chi2 test (Q-test)P