year : first year annual pattern course: pharmaceutics-i ... · hydroxide, calcium hydroxide,...

17
School: School of Pharmaceutical Sciences Programme:D.Pharmacy Year : First Year Annual Pattern Course: PHARMACEUTICS-I Course Code:DPY101 Theory: 3Hrs/Week Max. University Theory Examination: 80 Marks Max. Time for Theory Exam.:3Hrs Internal Examination: 20 Marks Objectives 1 The objective of the course is to familiarize students with different aspects of pharmaceutics whichinclude different dosage form and their classification, manufacturing process and uses. Further, it includes thepacking of pharmaceuticals and their size reduction, size separation, mixing, drying, filtration, extraction,distillation and sterilization processes. Moreover, the syllabus provides a depth understanding on Ayurvedic formulations and immunological products. Unit Number Details Hours 1 Introduction of different dosage forms: - Their classification with examples-their relative applications. Familiarization with new drug delivery systems. 04 2 Introduction to Pharmacopoeias: -with special reference to the Indian Pharmacopoeia. 03 3 Metrology Systems of weights and measures: - Calculations including conversion from one to another system. Percentage calculations and adjustments of products. Use of allegation method in calculations, isotonic solutions. 04 4 Packing of Pharmaceuticals: - Desirable features of a container types of containers. Study of glass and plastics as materials for containers and rubber as material for closures-their merits and demerits. Introduction to aerosol packaging. 05 5 Size reduction: - Objectives and factors affecting size reduction, methods of size reduction Study of Hammer mill, Ball mill, Fluid Energy Mill and Disintegrator. 05 6 Size separation: - Size separation by sifting. Official Standard for powders. Sedimentation methods of size separation. Construction and working of cyclone separator. 06 7 Mixing and Homogenization: - Liquid mixing and powder mixing, Mixing of semisolids, Study of Silver son Mixer Homogenizer, Planetary Mixer; Agitated powder mixer; Triple Roller Mill; Propeller Mixer, Colloid Mill and Hand Homogenizer. Double cone mixer. 06 8 Clarification and Filtration: - Theory of filtration, Filter media; Filter aids and selection of filters. Study of the following filtration equipments Filter Press, Sintered Filters, Filter Candles, Metafilter. 04 9 Extraction and Galenicals. (a) Study of percolation and maceration and their modification, continuous hot extraction Applications in the preparation of tinctures and extracts.(b) Introduction to Ayurvedic dosage forms. 04 10 Heat processes Evaporation: - Definition Factors affecting evaporation- 03

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Page 1: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

School: School of Pharmaceutical Sciences Programme:D.Pharmacy

Year : First Year Annual Pattern

Course: PHARMACEUTICS-I Course Code:DPY101

Theory: 3Hrs/Week Max. University Theory Examination: 80 Marks

Max. Time for Theory Exam.:3Hrs Internal Examination: 20 Marks

Objectives

1 The objective of the course is to familiarize students with different aspects of pharmaceutics

whichinclude different dosage form and their classification, manufacturing process and uses.

Further, it includes thepacking of pharmaceuticals and their size reduction, size separation,

mixing, drying, filtration, extraction,distillation and sterilization processes. Moreover, the

syllabus provides a depth understanding on Ayurvedic formulations and immunological

products.

Unit

Number Details Hours

1

Introduction of different dosage forms: - Their classification with

examples-their relative applications. Familiarization with new drug delivery

systems.

04

2 Introduction to Pharmacopoeias: -with special reference to the Indian

Pharmacopoeia. 03

3

Metrology Systems of weights and measures: - Calculations including

conversion from one to another system. Percentage calculations and

adjustments of products. Use of allegation method in calculations, isotonic

solutions.

04

4

Packing of Pharmaceuticals: - Desirable features of a container types of

containers. Study of glass and plastics as materials for containers and rubber

as material for closures-their merits and demerits. Introduction to aerosol

packaging.

05

5

Size reduction: - Objectives and factors affecting size reduction, methods of

size reduction Study of Hammer mill, Ball mill, Fluid Energy Mill and

Disintegrator.

05

6

Size separation: - Size separation by sifting. Official Standard for powders.

Sedimentation methods of size separation. Construction and working of

cyclone separator.

06

7

Mixing and Homogenization: - Liquid mixing and powder mixing, Mixing

of semisolids, Study of Silver son Mixer Homogenizer, Planetary Mixer;

Agitated powder mixer; Triple Roller Mill; Propeller Mixer, Colloid Mill

and Hand Homogenizer. Double cone mixer.

06

8

Clarification and Filtration: - Theory of filtration, Filter media; Filter aids

and selection of filters. Study of the following filtration equipments Filter

Press, Sintered Filters, Filter Candles, Metafilter.

04

9

Extraction and Galenicals. (a) Study of percolation and maceration and

their modification, continuous hot extraction Applications in the preparation

of tinctures and extracts.(b) Introduction to Ayurvedic dosage forms.

04

10 Heat processes Evaporation: - Definition Factors affecting evaporation- 03

Page 2: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

Study of evaporating still and Evaporating Pan.

11

Distillation: - Simple distillation and Fractional distillation; Steam

distillation and vacuum distillation. Study of vacuum still, preparation of

Purified Water I.P. and water for injection I.P. Construction and working of

the still used for the same.

05

12 Introduction to drying processes: - Study of Tray Dryers, Fluidized Bed

Dryer, Vacuum Dryer and Freeze Dryer. 03

13

Sterilization: - Concept of sterilization and its differences from

disinfection-Thermal resistance of microorganisms. Detailed study of the

following sterilization process.

(i) Sterilization with moist heat,

(ii) Dry heat sterilization,

(iii) Sterilization by radiation,

(iv) Sterilization by filtration and

(v) Gaseous sterilization.

Aseptic techniques: -Application of sterilization processes in hospitals

particularly with reference to surgical dressings and intravenous fluids.

Precautions for safe and effective handling of sterilization equipment.

07

14

Processing of Tablets: - Definition; Different types of compressed tablets

and their properties. Processes involved in the production of tablets; Tablets

excipients; Defects in tablets. Evaluation of Tablets; Physical Standards

including Disintegration and Dissolution. Tablet coating sugar coating; film

coating, enteric coating and microencapsulation (Tablet coating may be dealt

in an elementary manner.)

07

15

Processing of Capsules: - Hard and soft gelatin capsules; different sizes

capsules; filling of capsules; handling and storage of capsules, Special

applications of capsules.

05

16 Study of immunological products like sera vaccines, toxoids & their

preparations. 04

Total 75

Resources

Recommended

Books

1. Kasture, P.V., Pharmaceutics I theory, Nirali publication.

2. Gupta A.K., Pharmaceutics I, CBS publication.

3. Mehta R.M., Pharmaceutics I, Vallabh publication.

Reference Books 1.Remington’s Pharmaceutical Sciences.

2. Indian Pharmacopoeia.

Page 3: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

School: School of Pharmaceutical Sciences

Programme: D.Pharmacy

Year: First Year Annual Pattern

Course: Pharmaceutics I Practical Course Code: DPY111

Practical: Diploma - 4 Hrs./Batch

(20 Students)

Max. University Practical Exam.: 80 Marks

Internal Examination: 20 Marks

Objectives

1 To study different types of dosage forms & their bio-availability in different dosage forms.

2 Development of formulation using excellent &economic excipients.

3 Studying problems faced in manufacturing & method to rectify those problems.

4 The labeling of different dosage form according to Drugs & Cosmetic Act.

Sr.

No. Description

1 To prepare Aromatic waters.(3 Preparations)

2 To prepare Solutions (4 Preparations)

3 To prepare Spirits (2 Preparations)

4 To prepare Tinctures. (4 Preparations)

5 To prepare Extracts. (2 Preparations)

6 To prepare Creams. (2 Preparations)

7 To prepare Cosmetic preparations. (3 Preparations)

8 To prepare Capsules. (2 Preparations)

9 To prepare Tablets. (2 Preparations)

10 Preparations involving sterilization. (2 Preparations)

11 To prepare Ophthalmic preparations. (2 Preparations)

12 Preparations involving aseptic techniques. (2 Preparations)

Practical/Oral/Presentation:

Practical/Oral/Presentation shall be conducted and assessed jointly by internal and external examiners.

The performance in the Practical/Oral/Presentation examination shall be assessed by at least a pair of

examiners appointed as examiners by the University. The examiners will prepare the mark/grade sheet

in the format as specified by the University, authenticate and seal it. Sealed envelope shall be

submitted to the head of the department or authorized person.

Page 4: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

School: School of Pharmaceutical Sciences Programme: D.Pharmacy

Year : First Year Annual Pattern

Course: PHARMACEUTICAL

CHEMISTRY-I

Course Code: DPY102

Theory: 3 Hrs/Week Max. University Theory Examination: 80 Marks

Max. Time for Theory Exam.: 3 Hrs Internal Examination: 20 Marks

Objectives

1

The objective of the course is to help students attain a basic proficiency in the area of

InorganicChemistry, which includes: Acid and basis, Antioxidants, Gastrointestinal agents,

Topical agents, Dental products, Inhalants, Respiratory stimulants, Expectorants and Emetics,

Antidotes, Inorganic official compounds, Major ingredient, Extracellular electrolytes. Further,

they will learn about Radiopharmaceutical and contrast media, Quality control of drugs and

pharmaceuticals and Identification tests and Limit tests used to detect impurities in

Pharmaceutical substance as per Indian Pharmacopoeia.

Unit

Number Details Hours

1

General discussion on the following inorganic compounds including important

physical and chemical properties, medicinal and Pharmaceutical uses, storage

conditions and chemical incompatibility.

(A) Acids, bases and buffers: - Boric acid*, Hydrochloric acid, strong ammonium

hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers.

(B) Antioxidants: - Hypo-phosphorous acid, Sulphur dioxide, Sodium bisulphite,

Sodium metabisulphite, Sodium thiosulphate, Nitrogen and Sodium Nitrite.

(C) Gastrointestinal agents: - (i) Acidifying agents: - Dilute hydrochloric acid.

(ii) Antacids: - Sodium bicarbonate, Aluminium hydroxide gel, Aluminium

Phosphate, Calcium carbonate, Magnesium carbonate, Magnesium trisilicate,

Magnesium oxide, Combinations of antacid preparations.

(iii) Protectives and Adsorbents: - Bismuth subcarbonate and Kaolin.

(iv) Saline Cathartics: - Sodium potassium tartrate and Magnesium sulphate

(D) Topical Agents:- (i) Protectives: - Talc, Zinc Oxide, Calamine, Zinc stearate, Titanium dioxide,

Silicone polymers.

(ii) Antimicrobials and Astringents: - Hydrogen peroxide*, Potassium

permanganate, Chlorinated lime, Iodine, Solutions of Iodine, Povidone-iodine, Boric

acid, Borax. Silver nitrate, Mild silver protein, Mercury, Yellow mercuric oxide,

Ammoniated mercury.

(iii) Sulphur and its compounds: - Sublimed sulphur precipitated sulphur, selenium

sulphide.

(iv) Astringents: - Alum and Zinc Sulphate.

(E) Dental Products: - Sodium Fluride, Stannous Flouride, Calcium carbonate,

53

Page 5: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

Sodium metaphosphate, Dicalcium phosphate, Strontium chloride, Zinc chloride.

(F) Inhalants: - Oxygen, Carbon dioxide, Nitrous oxide.

(G) Respiratory stimulants: - Ammonium Carbonate.

(H) Expectorants and Emetics: - Ammonium chloride, Potassium iodide*,

Antimony potassium tartrate.

(I) Antidotes: - Sodium nitrate.

2

Major Intra and Extracellular electrolytes: - (A) Electrolytes used for replacement therapy: - Sodium chloride and its

preparations, Potassium chloride and its preparations.

(B) Physiological acid-base balance and electrolytes used: - Sodium acetate,

Potassium acetate, Sodium bicarbonate injection, Sodium citrate, Potassium citrate,

Sodium lactate injection, Ammonium chloride and its injection.

(C) Combination of oral electrolyte powders and solutions.

07

3 Inorganic Official compounds of Iron, Iodine, and, Calcium Ferrous Sulfate and

Calcium gluconate. 03

4

Radio pharmaceuticals and Contrast media: - Radio activity-Alpha, Beta and

Gamma Radiations, Biological effects of radiations, Measurement of radio activity,

G. M. Counter Radio isotopes their uses, storage and precautions with special

reference to the official preparations.

Radio opaque Contrast media: - Barium sulfate.

05

5

Quality control of Drugs and Pharmaceuticals: - Importance of quality control,

significant errors, methods used for quality control, sources of impurities in

Pharmaceuticals, Limit tests for Arsenic, chloride, sulphate, Iron and Heavy metals.

04

6 Identification tests for cation’s and anion’s as per Indian Pharmacopoeia. 03

Total 75

Resources

Recommended

Books

1. Kasture, A. V. &Wadodkar, S. G., Pharmaceutical Chemistry I, Nirali publication.

2. Mohd. Ali, Pharmaceutical Chemistry I, CBS publication.

3. Tipnis H.P. &Dhake A.S., Pharmaceutical Chemistry I, Vrinda publication.

4. Mahadik K.R. &Kuchekar B.S., Textbook of Pharmaceutical Chemistry, Nirali

publication. 5. Chitre, Jain, Exp. Pharmaceutical Chemistry, Career publication. 6. Belsare D.P., Inorganic Pharmaceutical Chemistry I (practical), Nirali publication. 7. Indian Pharmacopoeia.

Page 6: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

School: School of Pharmaceutical Sciences Programme: D.Pharmacy

Year: First Year Annual Pattern

Course: Pharmceutical Chemistry- I

Practical

Course Code: DPY112

Practical: Diploma - 3 Hrs./Batch

(20 Students)

Max. University Practical Exam.: 80 Marks

Internal Examination: 20 Marks

Objectives

1 The practicability of obtaining a reasonable standard of purity in raw material or in final

product,drug, medicine.

2 To decrease the cumulative and toxic effects of impurities present in drugs

3 By performing the tests like

a. Assays

b. Limit tests

c. Identification tests

One can uphold the practicability of drugs for internal use.

4 After performing the tests, the final product of good commercial quality can be obtained.

Sr.

No. Description

1 Identification tests for inorganic compounds particularly drugs and pharmaceuticals.

2 Limit test for chloride, sulfate, Arsenic, Iron and Heavy metals.

3 Assay of inorganic Pharmaceuticals involving each of the following methods of compounds

marked with (*) under theory.

a. Acid-Base titrations (at least 3)

b. Redox titrations (One each of Permanganometry and iodimetry)

c. Precipitation titrations (at least 2)

d. Complexometric titrations (Calcium and Magnesium)

Practical/Oral/Presentation:

Practical/Oral/Presentation shall be conducted and assessed jointly by internal and external examiners.

The performance in the Practical/Oral/Presentation examination shall be assessed by at least a pair of

examiners appointed as examiners by the University. The examiners will prepare the mark/grade sheet

in the format as specified by the University, authenticate and seal it. Sealed envelope shall be

submitted to the head of the department or authorized person.

Page 7: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

School: School of Pharmaceutical Sciences Programme: D.Pharmacy

Year : First Year Annual Pattern

Course: Pharmacognosy

Course Code: DPY103

Theory: 3 Hrs/Week Max. University Theory Examination: 80 Marks

Max. Time for Theory Exam.: 3 Hrs Internal Examination: 20 Marks

Objectives

1

The basic objective of the course is to provide an opportunity to understand the cultivation and

Utilization aspects of drugs. Further, the students will be able to identify some drugs available

in the healthcare system that are obtained or sourced from natural products. Moreover, the

students will have depth knowledge on the techniques of extraction, identification, separation

of natural compounds and their identification through morphological characters, physical and

chemical tests.

Unit

Number Details Hours

1 Definition, history and scope of Pharmacognosy including indigenous

system of medicine. 03

2 Various systems of classification of drugs of natural origin. 03

3 Adulteration and drug evaluation; significance of Pharmacopoeial

standards.

4

Brief outline of occurrence, distribution, outline of isolation, identification

tests, therapeutic effects and pharmaceutical applications of alkaloids,

terpenoids, glycosides, volatile oils, tannins and resins.

06

5

Occurrence, distribution, organoleptic evaluation, chemical constituents

including tests wherever applicable and therapeutic efficacy of following

categories of drugs.

(a) Laxatives: - Aloes, Rhuburb, Castor oil, Ispaghula, Senna.

(b) Cardiotonics: - Digitalis, Arjuna.

(c) Carminatives & G.I. regulators: - Umbelliferous fruits, Coriander,

Fennel, Ajowan, Cardamom Ginger, Black pepper, Asafoetida, Nutmeg,

Cinnamon, Clove.

(d) Astringents: - Catechu.

(e) Drugs acting on nervous system: - Hyoscyamus, Belladonna, Aconite,

Ashwagandha, Ephedra, Opium, Cannabis, Nux vomica.

(f) Antihypertensives: - Rauwolfia.

(g) Antitussives: - Vasaka, Tolu balsam, Tulsi.

(h) Antirheumatics: - Guggul, Colchicum.

(i) Antitumour: - Vinca.

(j) Antileprotics: - Chaulmoogra Oil.

(k) Antidiabetics: - Pterocarpus, Gymnema, Sylvestro.

(l) Diuretics: - Gokhru, Punarrnava.

45

Page 8: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

(m) Antidysentrics: - Ipecacuanha

(n) Antiseptics and disinfectants: - Benzoin, Myrrh. Nim, curcuma.

(o) Antimalarials: - Cinchona.

(p) Oxytocics: - Ergot.

(q) Vitamines: - Shark liver Oil and Amla.

(r) Enzymes: - Papaya, Diastase, Yeast.

(s) Perfumes and flavouring agents: - Peppermint Oil, Lemon Oil, Orange

Oil, Lemon grass Oil, Sandalwood.

(t) Pharmaceutical aids: - Honey, Arachis Oil, Starch, Kaolin, Pectin,

Olive oil, Lanolin, Beeswax, Acacia, Tragacanth, Sodium alginate, Agar,

Guar gum, Gelatin.

(u) Miscellaneous: - Liquorice, Garlic, Picrorhiza, Dioscorea, Linseed,

Shatavari, Shankhapusphi, Pyrethrum, Tobacco.

6 Collection and preparation of crude drug for the market as exemplified by

Ergot, opium, Rauwolfia, Digitalis, Senna. 06

7 Study of source, preparation and identification of fibres used in sutures and

surgical dressings: - cotton, silk, wool and regenerated fibre. 06

8 Gross anatomical studies of: - Senna, Datura, Cinnamon, Cinchona,

Fennel, Clove, Ginger, Nux vomica &Ipecacuanha. 06

Total 75

Resources

Recommended

Books

1. Gokhale S.B., Kokate, C.K., Textbook of Pharmacognosy, Nirali publication.

2. Trease& Evan’s, Pharmacognosy, Saunders publication.

Reference Books 1. Walis,T.E., Pharmacognosy, CBS publication .

2. Mohd. Ali, Pharmacognosy, CBS publication, Vol. 1

3. Rangari V., Pharmacognosy&Phytochemistry, Career publication, Vol. 2

Page 9: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

School: School of Pharmaceutical Sciences Programme: D.Pharmacy

Year: First Year Annual Pattern

Course: Pharmacognosy Practical Course Code: DPY113

Practical: Diploma - 3 Hrs./Batch

(20 Students)

Max. University Practical Exam.: 80 Marks

Internal Examination: 20 Marks

Objectives

1 Acquire skills of operating compound microscope.

2 Develop creativity in section cutting using different attributes and materials.

3 To acquire skills of staining.

4 Ability to interpret from observation.

Sr.

No. Description

1 Identification of drug by morphological characters.

2 Physical and chemical tests for evaluation of drugs wherever applicable.

3 Gross anatomical studies (T.S.) of the following drugs: Senna, Datura, Cinnamon, Cinchona,

Coriander, Fennel, Clove, Ginger, Nuxvomica, Ipecacuanha.

4 Identification of fibres and surgical dressings.

Practical/Oral/Presentation:

Practical/Oral/Presentation shall be conducted and assessed jointly by internal and external examiners.

The performance in the Practical/Oral/Presentation examination shall be assessed by at least a pair of

examiners appointed as examiners by the University. The examiners will prepare the mark/grade sheet

in the format as specified by the University, authenticate and seal it. Sealed envelope shall be

submitted to the head of the department or authorized person.

Page 10: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

School: School of Pharmaceutical Sciences Programme: D.Pharmacy

Year : First Year Annual Pattern

Course: Biochemistry and Clinical Pathology Course Code: DPY104

Theory: 2 Hrs/Week Max. University Theory Examination: 80 Marks

Max. Time for Theory Exam.: 3 Hrs Internal Examination: 20 Marks

Objectives

1.

2.

3.

To provides a better understanding in the fundamental chemical principles of the complex

biological systems.

The objective of the course is to provide integrated knowledge and understanding of the basics

of biochemistry.

To provides information about sources, chemical structures, metabolism and biological

functions of biomolecules.

Unit

Number Details Hours

1 Introduction to biochemistry. 04

2 Brief chemistry and role of proteins, polypeptides and amino acids,

classification, Qualitative tests, Biological value, Deficiency diseases. 06

3 Brief chemistry and role of Carbohydrates, Classification, qualitative

tests, Diseases related to carbohydrate metabolism. 06

4 Brief chemistry and role of Lipids, Classification, qualitative tests.

Diseases related to lipids metabolism. 06

5 Brief chemistry and role of Vitamins and Coenzymes. 04

6 Role of minerals and water in life processes. 04

7 Enzymes: - Brief concept of enzymic action; Factors affecting it,

Therapeutic and pharmaceutical importance. 05

8 Brief concept of normal and abnormal metabolism of proteins,

carbohydrates and lipids. 05

9

Introduction to pathology of blood and urine.

(a) Lymphocytes and Platelets, their role in health and disease.

(b) Erythrocytes Abnormal cells and their significance.

(c) Abnormal constituents of urine and their significance in diseases.

10

Total 50

Page 11: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

Resources

Recommended

Books

1. Chaudhari, M. R. &Gokhale, S.B., Biochemistry & Clinical Pathology, Nirali

publication.

2. Murugesh N., Biochemistry & Clinical Pathology, Sathya publication.

3. Sharma &Riyat, Practical Biochemistry & Clinical Pathology.

4. Umekar M.J., Biochemistry Career publication.

5. Pillai K.K &Quadry J.S., Biochemistry & Clinical Pathology, CBS publication.

6. Dandiya P.C, Sharma P.K., Biochemistry & Clinical Pathology, Vallabh

publication.

7. Kulkarni M.V, Rathod S.S, Biochemistry, Nirali publication.

8. Vyas S.P. &Kohli D.V., Pharmaceutical Biochemistry, Vrinda publication.

Reference Books 1. Deb A. C., Fundamentals of Biochemistry, New Central Book agency.

2. Satyanarayana U., Biochemistry, Book & Allied (P) Ltd.

3. David Plummer, An Introduction to practical Biochemistry, Mc graw Hill

publication.

4. Dinesh Puri, Textbook of Medical Biochemistry, Elsevier publication.

5. Murray R.K. &Granner D.K., Harper’s Illustrated Biochemistry, Mc graw Hill

publication.

Page 12: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

School: School of Pharmaceutical Sciences Programme: D.Pharmacy

Year: First Year Annual Pattern

Course: Biochemistry & Clinical Pathology

Practical

Course Code: DPY114

Practical: Diploma - 3 Hrs./Batch

(20Students)

Max. University Practical Exam.: 80 Marks

Internal Examination: 20 Marks

Objectives

1 To understand the concept of working of each laboratory equipment.

2 To identify corrosive, irritant chemicals and to take care during its handling.

3 Application of chemical test of carbohydrates to identify given sample of carbohydrate

according to concept structure.

4 To understand formation of precipitate.

5 Development of ability to distinguish the colors while performing various chemical tests.

6 Application of chemical test of protein to identify given sample of protein

according to concept structure.

7 Application of chemical test of amino acid to identify given sample of amino acid

according to concept structure.

Sr.

No. Description

1 Detection and identification of Proteins, Amino acids, Carbohydrates and lipids.

2 Analysis of normal and abnormal constituents of Blood and Urine (Glucose, Urea, Creatine,

creatinine, cholesterol, alkaline phosphatase, acid phosphatase, Bilirubin, SGPT, SGOT,

Calcium, Diastase, Lipase).

3 Examination of sputum and faeces(microscopic and staining).

4 Practice in injecting drugs by intramuscular, subcutaneous and intravenous routes. Withdrawal

of blood samples.

Practical/Oral/Presentation:

Practical/Oral/Presentation shall be conducted and assessed jointly by internal and external examiners.

The performance in the Practical/Oral/Presentation examination shall be assessed by at least a pair of

examiners appointed as examiners by the University. The examiners will prepare the mark/grade sheet

in the format as specified by the University, authenticate and seal it. Sealed envelope shall be

submitted to the head of the department or authorized person.

Page 13: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

School: School of Pharmaceutical Sciences Programme: D.Pharmacy

Year : First Year Annual Pattern

Course:Human Anatomy and Physiology

Course Code: DPY105

Theory: 3 Hrs/Week Max. University Theory Examination: 80 Marks

Max. Time for Theory Exam.: 3 Hrs Internal Examination: 20 Marks

Objectives

1.

2.

To develop a vocabulary of appropriate terminology to effectively communicate information

related to anatomy and physiology.

To provides a better understanding on the fact to recognize the anatomical structures and

explain the physiological functions of body systems (Respiratory, Cardiovascular, Digestive,

Urinary system including all sense organs).

Unit

Number Details Hours

1 Scope of Anatomy and Physiology. Definition of various terms used in

Anatomy 04

2 Structure of cell, function of its components with special reference to

mitochondria and microsomes. 03

3 Elementary tissues of the body. i.e epithelial tissue, muscular tissue, connective

tissue and nervous tissue. 04

4 Structure and function of skeleton. Classification of joints and their function,

Joint disorder. 05

5 Composition of blood, functions of blood elements. Blood group and

coagulation of blood. Brief information regarding disorders of blood. 05

6 Name and functions of lymph glands. 03

7

Structure and functions of various parts of the heart. Arterial and venous

systems with special reference to the names and positions of main arteries and

veins. Blood pressure and its recording. Brief information about cardiovascular

disorders.

08

8 Various parts of respiratory system and their functions. Physiology of

respiration. 04

9

Various parts of urinary system and their functions, structure and functions of

kidney. Physiology of Urine formation. Pathophysiology of renal diseases and

Oedema.

06

10

Structure of skeletal muscle. Physiology of muscle contraction,Names, position,

attachments and functions of various skeletal muscles. Physiology of

neuromuscular junction.

04

11 Various parts of central nervous system, brain and its parts, functions and reflex

action. Anatomy and Physiology of autonomic nervous system. 07

12 Elementary knowledge of structure and functions of the organs of taste, smell, 06

Page 14: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

ear, eye and skin. Physiology of pain.

13

Digestive system; names of the various parts of digestive system and their

functions. Structure and functions of liver, physiology of digestion and

absorption.

07

14 Endocrine glands and Hormones. Locations of the glands, their hormones and

functions. Pituitary, thyroid, Adrenal and Pancreas. 06

15 Reproductive system -Physiology and Anatomy of Reproductive system. 03

Total 75

Resources

Recommended

Books

1. Murugesh N., Basic Anatomy & Physiology, Sathya publication.

2. Bhise S.B. & Yadav A.V., Human Anatomy & Physiology, Nirali publication.

3. Rahul Phate, Human Anatomy & Physiology, Career publication.

4. John E. Hall Guyton's, Medical Physiology, Elsevier publication.

Reference Books 1. Chaurasia B.D., Human Anatomy, CBS publication Vol. 1, Vol.2, Vol.3.

2. Sembulingam K. Eassentials of Medical Physiology, Jaypee Brothers

publication. .

3. Singh Vishram Anatomy of Abdomen & Lower Limb; Elsevier publication;

4th Edition.

4. Vishram Singh, Anatomy of Head Neck & Brain, Elsevier publication, 3rd

Edition.

5. Singh V., Anatomy of Upper Limb & Thorax, Elsevier publication.

6. Guyton & Hall, Textbook of Medical Physiology, Elsevier publication, 11th

Edition

7. Basak A.K., Physiology Made Easy, NCBA Publication.

8. Pal G.K & Pal P., Textbook of Practical Physiology Univ., Press publication,

3rd Edition.

9. Drake, Vogl, & Mitchell, Gray’s Anatomy for Students, Churhil Livingstone

publication, 2nd Edition.

Page 15: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

School: School of Pharmaceutical Sciences Programme: D.Pharmacy

Year: First Year Annual Pattern

Course: Human Anatomy & Physiology

Practical

Course Code: DPY115

Practical: Diploma - 2 Hrs./Batch

(20 Students)

Max. University Practical Exam.: 80 Marks

Internal Examination: 20 Marks

Objectives

1 To know the structure and function of human body.

2 Study of various techniques of surgeries.

3 To know parameters of normal health.

4 To know various body cavities.

5 To understand aseptic techniques & sterilizations.

6 Development of ability in proper mixing of blood & antisera.

Sr.

No. Description

1 Study of the human skeleton.

2 Study with the help of charts and models of the following systems and organs:

(a) Digestive system. (b) Respiratory system.(c) Cardiovascular system. (d) Urinary system.

(e) Reproductive system. (f) Nervous system. (g) Eye. (h) Ear.

3 Microscopic examination of epithelial tissue, cardiac muscle, smooth muscle, skeletal muscle.

Connective tissue and nervous tissues.

4 Examination of blood films for TLC, DLC and malarial parasite.

5 Determination of clotting time of blood, erythrocyte sedimentation rate and Hemoglobin value.

6 Recording of body temperature, pulse, heart rate, blood pressure and ECG.

Practical/Oral/Presentation:

Practical/Oral/Presentation shall be conducted and assessed jointly by internal and external examiners.

The performance in the Practical/Oral/Presentation examination shall be assessed by at least a pair of

examiners appointed as examiners by the University. The examiners will prepare the mark/grade sheet

in the format as specified by the University, authenticate and seal it. Sealed envelope shall be

submitted to the head of the department or authorized person.

Page 16: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

School: School of Pharmaceutical Sciences Programme: D.Pharmacy

Year : First Year Annual Pattern

Course:Health Education and Community

Pharmacy

Course Code: DPY106

Theory: 2 Hrs/Week Max. University Theory Examination: 80 Marks

Max. Time for Theory Exam.: 3 Hrs Internal Examination: 20 Marks

Objectives

1 The course is designed to provide basic understanding on concepts of health, nutritional

values, first aids and family planning’s. Further, the course will make understand the basic

principles of diagnosis and management of several communicable and non-communicable

diseases.

Unit

Number Details Hours

1

Concept of health: - Definition of physical health, mental health, social

health, spiritual health determinants of health, indicators of health, concept

of disease, natural history of diseases, the disease agents, concept of

prevention of diseases.

05

2

Nutrition and health: - Classification of foods requirements, disease

induced due to deficiency of proteins, Vitamins and minerals-treatment and

prevention. 05

3

Demography and family planning: - Demography cycle, fertility, family

planning, contraceptive methods, behavioral methods, natural family

planning method, chemical method, mechanical methods, hormonal

contraceptives, population problem of India.

06

4

First aid: - Emergency treatment in shock, snake-bite, burns poisoning,

heart disease, fractures and resuscitation methods. Elements of minor

surgery and dressings.

04

5

Environment and health: - Sources of water supply, water pollution,

purification of water, health and air, noise light-solid waste disposal and

control-medical entomology, arthropod borne diseases and their control,

rodents, animals and diseases.

05

6 Fundamental principles of microbiology: - classification of microbes,

isolation, staining techniques of organisms of common diseases. 05

7

Communicable diseases: - Causative agents, modes of transmission and

prevention.

(a) Respiratory infections: - Chicken pox, measles. Influenza, diphtheria,

whooping cough and tuberculosis.

(b) Intestinal infections: - Poliomyelitis. Hepatitis. Cholera. Typhoid,

Food poisoning, Hookworm infection.

(c) Arthropod borne infections: - Plague, Malaria, Filariasis.

(d) Surface infections: - Rabies, Trachoma, Tetanus, Leprosy.

10

Page 17: Year : First Year Annual Pattern Course: PHARMACEUTICS-I ... · hydroxide, Calcium hydroxide, Sodium hydroxide and official buffers. (B) Antioxidants: - Hypo-phosphorous acid, Sulphur

(e) Sexually transmitted diseases: - Syphilis. Gonorrhoea. AIDS.

8 Non-communicable diseases: - Causative agents, prevention, care and

control; Cancer, Diabetes, Blindness, Cardiovascular diseases. 03

9

Epidemiology: - Its scope, methods, usesand dynamics of disease

transmission, immunity and immunization: Immunological products and

their dose schedule. Principles of disease control and prevention, hospital

acquired infection, prevention and control. Disinfection, types of

disinfection, disinfection procedures, for faeces, urine, sputum, room linen,

dead-bodies, instruments.

07

Total 50

Resources

Recommended

Books

1. Bhise S.B. & Yadav A.V., Health Education & Community Pharmacy, Nirali

publication, 20th Edition.

2. Gupta A.K., Health Education & Community Pharmacy, CBS publication.

3. Murugesh N., Health Education & Community Pharmacy, Sathya publication,

4th Edition.