what every man (and woman) needs to know about prostate cancer a frank discussion about prostate...

What Every Man (and Woman)

Needs To Know About Prostate Cancer

A frank discussion about

Prostate Cancerby John Tassi

May 7, 2009 Prostate Cancer Discussion by John Tassi

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Disclaimer• If you feel uncomfortable about discussions relating to the male reproductions system, this discussion may not be for you.• Health Insurance Portability and Accountability Act of 1996 (HIPAA) Privacy Rule. DO NOT TELL ME ABOUT YOUR MEDICAL CONDITIONS. Health Information Privacy • The Office for Civil Rights enforces the HIPAA Privacy Rule, which protects the privacy of individually identifiable health information, and the confidentiality provisions of the Patient Safety Rule, which protect identifiable information being used to analyze patient safety events and improve patient safety. • Learn about the Privacy Rule’s protection of the privacy of individually identifiable health information, the rights granted to individuals, OCR’s enforcement activities, and how to file a complaint with OCR.• The regulation implementing the Patient Safety and Quality Improvement Act of 2005 (PSQIA) was published on November 21, 2008, and became effective on January 19, 2009. View the Patient Safety Rule (42 C.F.R. Part 3).• PSQIA establishes a voluntary reporting system to enhance the data available to assess and resolve patient safety and health care quality issues. To encourage the reporting and analysis of medical errors, PSQIA provides Federal privilege and confidentiality protections for patient safety information called patient safety work product. Patient safety work product includes information collected and created during the reporting and analysis of patient

safety events.• The confidentiality provisions will improve patient safety outcomes by creating an environment where providers may report and examine patient safety events without fear of increased liability risk. Greater reporting and analysis of patient safety events will yield increased data and better understanding of patient safety events.

OCR works in close collaboration with the Agency for Healthcare Research and Quality (AHRQ) which has responsibility for listing patient safety organizations (PSOs), the external experts established by the Patient Safety Act to collect and analyze patient safety information• Federal civil rights laws and the Health Insurance Portability and Accountability Act (HIPAA) Privacy Rule, together protect your fundamental rights of nondiscrimination and health information privacy. Civil Rights help to protect you from unfair treatment or discrimination, because of your race, color, national origin, disability, age, sex (gender), or religion. The Privacy Rule protects the privacy of your health information; it says who can look at and

receive your health information, and also gives you specific rights over that information. In addition, the Patient Safety Act and Rule establish a voluntary reporting system to enhance the data available to assess and resolve patient safety and health care quality issues and provides confidentiality protections for patient safety concerns.• OCR helps to protect you from discrimination in certain healthcare and social service programs. Some of these programs may include:• Hospitals, health clinics, nursing homes• Medicaid and Medicare agencies• Welfare programs• Day care centers• Doctors’ offices and pharmacies• Children’s health programs• Alcohol and drug treatment centers• Adoption agencies• Mental health and developmental disabilities agencies• By enforcing the Privacy Rule, OCR helps to protect the privacy of your health information held by health insurers and certain health care providers and health insurers. Some of these providers and insurers may include:• Doctors and nurses• Pharmacies• Hospitals, clinics, and nursing homes• Health insurance companies• Health maintenance organizations (HMOs)• Employer group health plans• Certain government programs that pay for health care, such as Medicare and Medicaid• OCR also enforces the confidentiality provisions of the Patient Safety Act and Rule.

• Epsum factorial non deposit quid pro quo hic escorol. Olypian quarrels et gorilla congolium sic ad nauseum. Souvlaki ignitus carborundum e pluribus unum. Defacto lingo est igpay atinlay. Marquee selectus non provisio incongruous feline nolo contendre. Gratuitous octopus niacin, sodium glutimate. Quote meon an estimate et non interruptus stadium.

• Sic tempus fugit esperanto hiccup estrogen. Glorious baklava ex librus hup hey ad infinitum. Non sequitur condominium facile et geranium incognito. Epsum factorial non deposit quid pro quo hic escorol. Marquee selectus non provisio incongruous feline nolo contendre Olypian quarrels et gorilla congolium sic ad nauseum. Souvlaki ignitus carborundum e pluribus unum.

• Defacto lingo est igpay atinlay. Marquee selectus non provisio incongruous feline nolo contendre. Gratuitous octopus niacin, sodium glutimate. Quote meon an estimate et non interruptus stadium. Sic tempus fugit esperanto hiccup estrogen. Glorious baklava ex librus hup hey ad infinitum. Non sequitur condominium facile et geranium incognito. Epsum factorial non deposit quid pro quo hic escorol. Olypian quarrels et gorilla congolium sic ad nauseum. Souvlaki ignitus carborundum e pluribus unum. Defacto lingo est igpay atinlay. Gratuitous octopus niacin, sodium glutimate.

• Quote meon an estimate et non interruptus stadium. Sic tempus fugit esperanto hiccup estrogen. Glorious baklava ex librus hup hey ad infinitum. Non sequitur condominium facile et geranium incognito.

















http://www.hhs.gov/ocr/privacy/hipaa/understanding/index.html


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Disclaimer• If you feel uncomfortable with discussions

relating to the male reproductions system, this seminar may not be for you.

• Health Insurance Portability and Accountability Act of 1996 (HIPAA) Privacy Rule. DO NOT TELL ME ABOUT YOUR MEDICAL CONDITIONS.

• ViaSat Inc. is not responsible for any content contained in this presentation or discussions by John Tassi.

• I am not a doctor. Anything I say is based on my research and knowledge about Prostate Cancer.


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What is a Prostate?

• The prostate is a walnut-sized gland that forms part of the male reproductive system.

• Scientists do not know all the prostate's functions.

• Primary function is to secrete a slightly alkaline fluid that forms part of the seminal fluid, a fluid that carries sperm.


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Normal Vs. Enlarged Prostate


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What is BPH• Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement

of the prostate that restricts the flow of urine from the bladder and is a common part of aging.

• The prostate goes through two main periods of growth.– The first occurs early in puberty, when the prostate doubles in

size. – At around age 25, the gland begins to grow again. This second

growth phase often results, years later, in BPH.• BPH rarely causes symptoms before age 40• More than half of men in their 60’s and as many as 90% in their 70’s

and 80’s have some symptoms of BPH.• As the prostate enlarges, the layer of tissue surrounding it stops it

from expanding, causing the gland to press against the urethra like a clamp on a garden hose.

• Many men feel uncomfortable talking about the prostate. Prostate enlargement is as common a part of aging as gray hair. As life expectancy rises, so does the occurrence of BPH. In the United States in 2000, there were 4.5 million visits to physicians for BPH.


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Symptoms of BPH• Many symptoms of BPH stem from obstruction of the urethra

and gradual loss of bladder function, which results in incomplete emptying of the bladder. The symptoms of BPH vary, but the most common ones involve changes or problems with urination, such as

– a hesitant, interrupted, weak stream – urgency and leaking or dribbling – more frequent urination, especially at night– the feeling that you have not fully voided

• It is important to tell your doctor about urinary problems.• In 8 out of 10 cases, these symptoms suggest BPH, but they

also can signal other, more serious conditions which include prostate cancer.


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What is Cancer?• Normal cells grow and divide to form new cells as the body needs

them. When normal cells grow old or get damaged, they die (Apoptosis), and new cells take their place.

• Sometimes, this process goes wrong. New cells form when the body doesn't need them, and old or damaged cells don't die as they should. The buildup of extra cells often forms a mass of tissue called a growth or tumor.

• Growths can be benign (not cancer) or malignant (cancer)• Cancer is a disease in which malignant (cancer) cells form in the

tissues of the host organ.• There are 2 types of Prostate Cancer:

– Hormone-depentent prostate cancer (Needs testosterone).– Hormone-refractory prostate cancer (HRPC)

• Think of cancer as one dandelion in the middle of your beautiful green lawn.


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3 Stages of Cancer

Think of planting a lawn• Initiation

– when you put the seeds in the soil

• Promotion– when the grass starts to grow

• Progression– when the grass gets completely out of control,

invading the driveway, the shrubbery and the sidewalk.


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First Stage - Initiation

• Initiation – When the initial cell mutates. Carcinogens, oxidants and genetics are some of the causes of cell mutation.

– Carcinogens are most often the byproducts of industrial chemicals. The National Institute for Occupational Safety and Health (NIOSH) lists 100’s of chemicals considers to be potential occupational carcinogens.

– http://www.cdc.gov/niosh/topics/cancer/npotocca.html

– Oxidants are health-threatening "free radicals”. There are over 50 degenerative diseases in which "free radicals" are implicated, including cancer and heart disease.


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First Stage - InitiationEvery cell in your body contains atoms, with a positively charged nucleus, and negatively charged electrons surrounding them. When your body is exposed to oxidants, electrons can be pulled out of orbit. When this happens, the atom, which is missing the electron, becomes unstable and begins to grab electrons from other nearby molecules to replace it, causing chain reactions. The unstable electrons are called "free radicals," because they have been freed or liberated from where they were. The chain reactions caused by liberated electrons can send "free radicals" throughout your blood stream and body creating havoc and even possibly setting the stage for cancer, heart disease and a host of other potentially fatal diseases.


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First Stage - InitiationHOW "FREE RADICALS DAMAGE YOUR BODY?"Think what would happen if a large crane were driven through the streets of Manhattan with an uncontrolled wrecking ball swinging from side to side. The skyscrapers might not fall, but they would be severely damaged. , That's similar to what 'free radicals" can do to your cells. "Free radicals" can start ricocheting off cells damaging the cell membranes and eventually damaging intracellular structures such as the mitochondria and nucleus. Without adequate antioxidant protection, they will eventually damage DNA, actually causing mutations. These mutations may result in cancer.


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Second Stage - Promotion

• Promotion in a cancer cell – When the mutated cell starts to divides uncontrolled with no growth regulation and no Apoptosis.– Apoptosis: Programmed cell death involves a series

of biochemical events leading to a cells death.– Cell populations go through a type of exponential

growth called doubling. Thus, each generation of cells should be twice as numerous as the previous generation.

• Prostate Cancer Requires nutrition– Testosterone– Blood flow, lots of blood flow. (Angiogenesis)(Ac-44)


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Third Stage - Progression

• Progression – when the cancer cell grows out of control and spreads from the original site.

• No longer organ confined.

• The cancer has spread, or metastasized.


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Symptoms of Prostate Cancer

The following symptoms may be caused by prostate cancer. Other conditions may cause the same symptoms.

A compitent urologist should be consulted if any of the following problems occur:

• Week or interrupted flow of urine. • Frequent urination. • Trouble urinating. • Pain or burning during urination. • Blood in the urine or seman. • A pain in the back, hips, or pelvis that doesn't go away. • Painful ejaculation.


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What I Have Learned(The Hard Way)

• If you have more than one of the above symptoms, find a competent urologist that specializes in Prostates. Get recommendations from friends and co-workers. Research online.

• You need to be your own case worker!• Keep copies of all tests.• Don’t assume the doctor is always right. Ask the doctor to

explain and justify his/her answer. (they really don’t like this)!• If you’re not happy with the care your doctor is giving you, fire

them!• Don’t accept “this is the standard of care” answers.• PSA test every year after 40.• DRE every year after 40. (only about 1/3 of the gland is

examined)


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What Should You Do?

• If you PSA velocity is increasing, (> 0.75ng/ml per year) put together a team of physicians you trust.

• Thoroughly research all options. Don’t expect the doctors to do this for you.

• Ask Questions, keep asking until you get the answer that makes sense.

• Always get second and third opinions.

• Rely on your family and friends for support and help.

• Keep Positive! Any day they’re not shoveling dirt on my face is a fantastic day!


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PC Risk Factors

• Genetic (3 – 10%) according to “The China Study”• First degree relative: 2.0 increased relative risk• Second degree relative: 1.7 increased relative risk• First and second degree relative: 8.8 increased relative

risk• African-American race 30-50% increased risk of

developing prostate cancer• lethargic (couch potato)• Eat the Western Diet (diet of affluence) • If you’re obese (extremely or unhealthily fat or

overweight)


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Are You Obese?


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Cancer Facts• Cancer is on pace to supplant heart disease as the No. 1 cause of death

worldwide in 2010• In the USA, one new case of prostate cancer occurs every 2.8 minutes and

a man dies from it every 19 minutes. • Lifetime risk of dying from prostate cancer is 3.4% for American men. Risk

of prostate cancer diagnosis is currently about 15% (USPSTF 1996).• Risk for prostate cancer rises sharply after age 50, with African American

men at higher risk for the disease than white or Asian men.• 25% of men with prostate cancer have PSA < 4.0ng/ml.• Estimated new cases and deaths from prostate cancer in the United States

in 2008:– New cases: 186,320– Deaths: 28,660

• 1 in 6 men will have prostate cancer in their lifetime• 1 in 32 men will die of this disease (2004)• 80% of PC is diagnosed in men over 65. (2000)


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Cancer Facts

• 2004 study in The New England Journal of Medicine found that up to nearly 15% of 3,000 men with PSA scores at or below the established threshold (4.0 ng/mL) and a normal digital rectal exam had prostate cancer.

• Breast cancer affects one in eight women, most before age 70.

• About 180,000 cases of breast cancer are diagnosed a year, and men are not immune — they comprise about one percent of the cases.


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Cancer Facts

• Recently 2 major studies have conflicting views on PSA screening

• American Urological Association – not all men over age 50 need to get annual tests, a

shift from the association's past recommendations.

• New England Journal of Medicine – a report from a European study that followed 182,000

patients over 15 years. This study found a 20-percent reduction in the death rate among those who were screened.


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What You Can DoWE LIVE in a chemical stew. So pervasive are the chemicals in the food we eat, in the products we use to keep our bodies, clothes, and houses clean, and in keeping our lawns manicured that it has become impossible to avoid them. We are surrounded by chemicals. Over 80,000 are in use and an additional 1,000-2,000 are introduced each year; however, only about 2 percent are tested by regulatory agencies for safety.

One chemical that has received a lot of attention lately is Bisphenol A, or BPA, an ingredient in plastics used to make reusable food and beverage containers (including baby bottles). It also coats the insides of food and beverage cans.

http://www.commondreams.org/view/2009/03/23-5 By Laura N. Vandenberg and Maricel V. Maffini March 23, 2009


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Diet - Proteins

• Casein makes up 87% of cows milk protein (TCS-59)

• Gluten – the protein of wheat (TCS-59)

• “The China Study”, sites one lab experiment:– 100 weeks in duration (rats life span is 2 yrs)– All were injected with an equal amount of Aflatoxin– Rats fed 5% Casein, cancer Initiation and Promotion

are near 0%. All were alive, active.– Rats fed 20% Casein, all were dead.– Some rats were switched during weeks 40 or 60.

• Rats switched from 20% to 5% had (35-40%) less tumor growth.

• Rats switched from 5% to 20% started growing tumors.


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Diet - Proteins

• Beef and chicken no longer range (grass) fed.• Hormones like estradiol and zeranol to fatten

them up faster.• Diets consist of Corn, Soy and Wheat, practically

no omega-3 fatty acids but high in omega-6.• The human body can not product omega-3 or 6.

– Omeg-6 causes inflammation, coagulation and stimulation of cell growth.

– Omega-3 regulates inflammation, fluidization of blood and regulates cell growth.


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What You Can Do• Maintain a healthy weight: Being overweight can increase the risk for certain types

of cancer and can increase the risk of recurrence in a person who already has cancer. If you are overweight you should lose weight with the guidance of a physician. A person undergoing cancer treatment, however, should talk with their physician before losing weight.

• Exercise regularly: If you are healthy, experts recommend that you exercise most days of the week for at least 30 minutes at a moderate to vigorous level in order to optimize health and help prevent cancer. Cancer survivors are also encouraged to exercise through most phases of treatment and survival. Cancer survivors should talk with their physician about the appropriate amount and duration of weekly exercise.

• Eat a balanced diet: Eat an abundance of organic fruits, vegetables, and whole grains, and include 3 to 6 portions of fish in the diet several times a week.

• Processed sugars: Reduce or eliminate all processed sugar and man-made sugar substitutes (Splenda, Equal, etc) as their all chemicals. Use instead natural sweetners like Stevia.

• Drink alcohol in moderation or not at all: Drinking alcohol may increase your risk of cancer and risk of recurrence of cancer. Talk with your doctor about the amount of alcohol that is safe to drink based on your specific health conditions.

• Don’t smoke: Smoking increases your risk of developing lung, throat, and mouth cancer. Smoking also increases the risk of cancer in the people around you through the well-known dangers of secondhand smoke.


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Suggested Reading


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What PC Looks Like

what every man (and woman) needs to know about prostate cancer a frank discussion about prostate...

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