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  • 1

    Spotlight on Parkinsons Disease

    Staying on Your Feet Balance Matters

    Tuesday, October 18, 2016

    WelcomeandIntroductions

    Stephanie PaulVice President Development and MarketingAmerican Parkinson Disease Association

    2

  • 2

    Presenters

    Tami Rork DeAngelis,PT, DPT, GCS

    Anna DePold Hohler,MD, FAAN

    3

    Presentation

    Anna DePold Hohler, MD, FAANAssistant Dean, Office of Clinical and Strategic Affiliations

    Director of the Center for Militaryand Post Deployment Health

    Associate Professor of NeurologyBoston University School of Medicine

    Boston, MA

    4

  • 3

    MedicationSideEffects

    BloodPressure

    MedicationTreatments

    ConservativeTreatments

    PhysicalTherapy

    PD MotorSymptoms

    BalanceMatters

    Interventions

    5

    PDMotorSymptoms

    6

  • 4

    ParkinsonsDiseaseMotorSymptoms

    PatientswithPDcanhavedifficultieswithpostureandwalkingwhichcanaffectbalance.

    Posturecanbestoopedaffectingbalance

    Walkingcanbeslowedwithscuffingwhichincreasestheriskoftripping

    7

    ComplicationsofTherapy

    Wearingoff

    Onoff

    Dyskinesias

    8

  • 5

    Wearingoff

    Overtimethereisaprogressivelossofdopamineinthebrain.

    Moremedicationisneededforsymptomcontrol.

    PatientsmayexperienceadropintheirdopaminelevelswhentheirpillsarewearingoffduringwhichtimetheirPDsymptomsworsen.

    Thiscanaffecttheirbalance.

    Thisisoftenmanagedwithincreasingdosingorpillfrequency.

    9

    OnOff

    Overtime,patientsmaydevelopsymptomfluctuations.

    TheONperiodiswhenapersonnoticesthattheirmedicationsareworking.

    TheOFFperiodiswhenthemedicationsarenotworking.

    Inmoreadvanceddiseasethereislessontime,moreofftime,andmoreonofffluctuations.

    Thismaybeimprovedbyincreasingthedoseofthemedication,morefrequentdosing,oraddingonmedications.

    http://www.wearingoff.eu/wpcontent/uploads/2013/08/WearingOffChart.jpg

    10

  • 6

    Dyskinesias

    Dyskinesiasaredancingmovementsthatpatientsmayexperienceaftertheyhavebeenondopaminergicmedicationsoftenfor5yearsormore

    Dyskinesiasmayaffectbalanceandincreaseriskoffalls.

    Theymaybemanagedbyspreadingoutmedicationsoraddingonaparticularmedicationfordyskinesias. http://www.centralneurosurgery.com.au/files/cache/cdcd243057a21728473dfdd546bd253f_f37.png11

    BloodPressure

    12

  • 7

    ParkinsonsDiseaseisassociatedwithanumberofnonmotordifficulties.

    Bloodpressurefluctuationsarecommon.

    ParkinsonsDiseaseNonMotorSymptoms

    http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/A/autonomic.gif13

    RegulationofBloodPressure

    FluctuationsinbloodpressureiscommonlyseeninPD

    Orthostatichypotensionisadropinthesystolicbloodpressure(topnumber)of20pointsoradropinthediastolicbloodpressure(bottomnumber)of10pointsafterchangingposition

    BloodpressureisfrequentlyworsenedbymedicationsusedinPD14

  • 8

    SymptomsofLowBloodPressure

    Fainting

    Falls

    Confusion

    Balancedifficulties

    Lightheadedness

    Weakness

    Allsymptomsoflowbloodpressureareworsewithstanding.

    15

    MedicationSideEffects

    16

  • 9

    MedicationSideEffects

    Dopaminemedicationscanoftendropbloodpressure

    Somepatientsarealsoonbloodpressuremedicationsthatlowerbloodpressure

    Somebladdermedicationsalsolowerbloodpressure

    17

    CorrectingOrthostaticHypotensionImprovesFunction

    PatientswithParkinsonsdiseasefrequentlyhaveorthostatichypotension

    Theymaynotbesymptomatic

    Theonlywaytoknowforsureisbydoingorthostaticbloodpressuremonitoring.

    Patientsshowedsignificantimprovementintheirmotorfunction,walking,balanceandcognitivefunctionwithtreatmentoforthostatichypotension

    18 HohlerAD,AmarieiDE,KatzDI,etal.TreatingOrthostaticHypotensioninPatientswith'ParkinsonsDiseaseImprovesFunction.JournalofParkinson'sDiseaseIssueVolume2,Number3,2012.

  • 10

    ConservativeTreatments

    19

    BloodPressureConservativeTreatment

    Slowpositionchanges

    Hydration6080ouncesperdayElectrolyterichfluids

    Addsalttothediet

    Compressionstockings

    Abdominalbinder http://www.staples.com/PolandSpringBottledWater169ozBottles24Case/product_71314020

  • 11

    MedicationTreatments

    21

    MedicationsUsedtoTreatLowBloodPressure

    Fludrocortisonecanbeusedtoexpandbloodvolume.SideEffectsinclude: swelling,headaches,weightgain,andhighbloodpressure

    Midodrinecanconstrictbloodvessels.SideEffectsincludehighbloodpressure,visionchanges,numbness,anditching

    Droxidopachemicallystimulatestheautonomicsystemandincreasesbloodpressure.Sideeffectsincludehighbloodpressure,headaches.

    22

  • 12

    Presentation

    Tami Rork DeAngelis, PT, DPT, GCSSenior Physical Therapist

    Center for NeurorehabilitationSargent College of Health and Rehabilitation Sciences

    Boston UniversityBoston, MA

    23

    PhysicalTherapy

    24

  • 13

    WhatDoWeNeedtoDotoKeepOurBalance?

    Maintainquietstanding Walkwithouttrippingorstumbling Anticipatechallengestobalance Tolerateunexpectedchallengestobalance

    25

    26

    WhatSystemsAreInvolvedinBalance?

    BalanceControl

    Strength, Flexibility

    and Posture

    Stabilityduringwalking

    SensorySystem

    (sight,innerear,etc)

    StabilityLimits

    Expectedposturalchanges

    Unexpectedposturalchanges

    AdaptedfromHorakFB,etal.TheBalanceevaluationSystemsTest(BESTest)todifferentiateBalanceDeficits.PhysicalTherapy2009;Vol89,5:484498

  • 14

    HowCanTheseSystemsBeAffectedinPeopleWithPD?

    27

    AdaptedfromHorak FB,etal.TheBalanceevaluationSystemsTest(BESTest)todifferentiateBalanceDeficits.PhysicalTherapy2009;Vol89,5:484498

    Decreasedhipstrength Decreasedankleflexibility Forwardflexedandstiffspine

    Strength,Flexibilityand

    Posture

    Catchingtoewhenwalking Trunkstiffness/rigidity

    Stability duringwalking

    Changesinprocessingofinformation ImpairedvisionSensory System

    28

    HowCanTheseSystemsBeAffectedInPeopleWithPD?(cont.)

    Delayedmuscleon Abnormalmusclecoordination

    Toobigortoolittleofaresponse

    Anklestiffness

    ExpectedPosturalChanges

    UnexpectedPosturalChanges

    StabilityLimits

  • 15

    CanPhysicalTherapyInterventionsImproveBalanceandDecreaseFalls?

    2929

    Case1:Bob

    63yearsold.PDfor5years.

    Reportstrippingwhenwalkinghisdog.

    Dailynearfalls,onefallinthelastyear.

    30

  • 16

    Case1:Bob

    PrimaryProblems

    Decreasedbalancereactions

    Stiffness Slowness

    SecondaryProblems

    Muscleweakness Decreasedflexibility Decreasedposture

    Maintainquietstanding Walkwithouttrippingorstumbling Anticipatechallengestobalance Tolerateunexpectedchallengestobalance

    31

    Case1:BobsPhysicalTherapy

    Strengtheningprogramforlegsandtrunk

    Gaittrainingontreadmillandovergroundwithametronomebeat

    Balancetraining

    Stretchingprogramforankleandhipmuscles

    Physicalactivityplan

    6monthfollowupappointment

    PhysicalTherapyTreatmentPlan

    32

  • 17

    Case2:Shirley

    68yearsold.PDfor12years.

    Losesbalancedaily,fallsweekly.

    Lossofbalance/fallsmostlyinevenings,whenturningandwhilecarryinggrocerybagsorreachingforphone.

    ExperiencesON/OFFtimesanddyskinesias.

    33

    Case2:Shirley

    PrimaryProblems

    Decreasedposturalreactions

    Stiffness Slowness

    SecondaryProblems

    Muscleweakness Decreasedflexibility Decreasedposture

    Maintainquietstanding Walkwithouttrippingorstumbling Anticipatechallengestobalance Tolerateunexpectedchallengesto

    balance

    Maintainquietstanding Walkwithouttrippingorstumbling Anticipatechallengestobalance Tolerateunexpectedchallengestobalance

    34

  • 18

    Case2:ShirleysPhysicalTherapy

    CheckinwithNeurologistformedicationadjustment.

    CompleteFalllog Balancetrainingactivities GaitTrainingactivities(withdual

    task) StrategyTrainingtomaximizesafety Exercisesforstrengthandflexibility. DischargetoTaiChi2Xperweek

    classANDFollowupin3monthsforbalanceassessment

    PhysicalTherapyTreatmentPlan

    35

    Conclusions

    Ateamapproachiskeywhenitcomestomanagingbalance.

    Preventionandearlytreatmentisideal.

    BalancecanbeimprovedthroughoutyourlifespanwithPD(Itsnevertoolate!).

    Keepmovingyourfeettostayonyourfeet!

    CalltheAPDARehabResourceCenterHelplinetofindaPTwithexpertiseinParkinsonsdiseasenearyou!(888)6061688

    36

  • 19

    Question&Answer

    Tami Rork DeAngelis,PT, DPT, GCS

    Anna DePold Hohler,MD, FAAN

    37

    ClosingRemarks

    Stephanie PaulVice President Development and MarketingAmerican Parkinson Disease Association

    38

  • 20

    Foradditionalinformation,answerstoyourquestions,orresources

    Pleasevisitourwebsitewww.apdaparkinson.org

    Orcallus18002232732

    39