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COMPOSITION OF NUCLEOTIDE

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  • 1. Prof vkmBIOTHE BIOWORLDbiologyvm@facebook.comGENE: ITS NATURE, EXPRESSION AND REGULATION

2. GENE-1 biologyvm@facebook.com 2 3. Nucleic acids: history biologyvm@facebook.com 3 4. biologyvm@facebook.com 4 5. NUCLEIC ACIDS: HISTORY Johannes Fridrich Miescher, a Swissbiologist who discovered a protamine inthe sperms of salmon in 1870. He also isolated nucleic acids from thenuclei of pus cells (dead white bloodcells) in 1869 at the university oftubingen in Germany Later also isolated from the sperms ofsalmon fish, He Called As Nuclein It Was Called Nucleic Acids By Altmanbiologyvm@facebook.com 5 6. DeoxyRiboseRiboseNucleic Acid Nucleic Acid biologyvm@facebook.com 6 7. NUCLEIC ACIDbiologyvm@facebook.com 7 8. biologyvm@facebook.com 9 9. PHOSPHORICACIDNUCLEOTIDE NUCLEOSIDE biologyvm@facebook.com 10 10. PHOSPHORICACID PENTOSESUGARNUCLEOTIDE NUCLEOSIDE NITROGEN BASEbiologyvm@facebook.com11 11. biologyvm@facebook.com 12 12. RIBOSE(C5H10O5)PENTOSE SUGAR DEOXY- RIBOSE (C5H10O4)biologyvm@facebook.com 13 13. biologyvm@facebook.com 14 14. biologyvm@facebook.com 15 15. biologyvm@facebook.com 16 16. biologyvm@facebook.com 17 17. biologyvm@facebook.com 18 18. biologyvm@facebook.com 19 19. biologyvm@facebook.com 20 20. biologyvm@facebook.com 21 21. biologyvm@gmail.com 22. biologyvm@facebook.com 23 23. biologyvm@facebook.com 24 24. DNA 25. NUCLEARDNA EUKARYOTICDNAORGANELLARDNADNAMAIN / CHROMOSOMALPROKARYOTICDNADNAEXTRACHROMOSOMAL DNA/ PLASMIDSbiologyvm@facebook.com 26 26. MITOCHONDRIANUCLEARCHLOROPLASTEUKARYOTIC DNAbiologyvm@facebook.com 27 27. NUCLEAR DNA EXTRA NUCELAR DNAFound in the nucleusFound in the cell organelles like mitochondria and chloroplast Linear and doubleCircular and doublestranded stranded Associated with the Associated with replicationinheritance/heredity of mitochondria and chloroplastsbiologyvm@facebook.com 29 28. EUKARYOTICNUCLEAR DNAbiologyvm@facebook.com 30 29. EUKARYOTIC:ORGANELLAR DNA biologyvm@facebook.com 31 30. EUKARYOTIC NUCLEAR DNA biologyvm@facebook.com 32 31. EUKARYOTIC NUCLEAR DNA For Eukaryotic Cells, Number OfDNA Molecules Corresponds ToNumber Of Chromosomes Per Cell DNA Content Is Constant In AllSomatic Cells (2n) Of A GivenSpecies The Gametes (n) Have Half TheAmount Of DNA As They ContainHalf The Number Of Chromosomes biologyvm@facebook.com 33 32. NEET ALERT The length of DNA is usuallydefined as number ofnucleotides (or a pair ofnucleotides referred to as basepairs) present in it. A haploid content of human DNAis 3.310 9 bp Escherichia coli has 4.6 10 6 bpbiologyvm@facebook.com 34 33. PROKARYOTIC DNAbiologyvm@facebook.com 35 34. PROKARYOTICDNAbiologyvm@facebook.com 36 35. PROKARYOTIC DNAChromosomal DNA Plasmid DNA Main/Chromosomal Extra-chromosomalDNA DNA Found in the Circular and double cytoplasm attached to stranded but not the cell membraneattached to the cell Circular and double membranestranded Responsible for the Responsible for additional properties like inheritance/heredity toxicity resistance,antibiotic resistance biologyvm@facebook.com 37 36. ANTIBIOTICRESISTANCE biologyvm@facebook.com 38 37. Prof vkmBIOTHE BIOWORLDbiologyvm@facebook.com09820469492 biologyvm@facebook.com 39

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