Update From Meeting with IBD

SpecialistDr. Shamita Shah

August 18th, 2009

Good News Fully supportive of the concept

Understands importance of and our reasoning behind both devices

Supports probiotic research

Enthusiastic for future implications of this device as a “treatment/diagnostic tool”

Willing to share her own slides on IBD and give 20 presentation on her current knowledge She has great statistics and can help us frame our device to tailor to a specific target audience

Next Steps Decide what “phase” of IBD we want to target Early diagnostic… difficult to distinguish between UC and Crohn’s, but certainly useful

Complementary treatment: use as another “tool” for clinicians

Post-treatment diagnostic to prevent recurrence…

Dr. Shah sees this as the most promising and necessary right now w/ regards to treatment

No previous probiotic research in this fieldMany cases lead to recurrence- and patients need annual colonic scopes

Meet w/ Dr. Shah again early September

Challenges We need numbers…

The “ratio” needs to be known or better understood and Dr. Shah doesn’t collect these numbers

When/how will the device be “triggered” with regards to these numbers?

Switch bacterial strain to be more sustainable in the small intestine?