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Page 1: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion
Page 2: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Contents

Introduction

Design of a Rotor

Why Rotors Fail

Warranty & Retirement Recommendations

Proper Use and Maintenance

Ultracentrifuge Classification Program

Field Rotor Inspection Program (FRIP)

Out-of-Warranty Rotors and Retirement

Preparative Ultracentrifuge Rotor Warranty

Special Ultracentrifuge e Rotor Warranty

Avanti i J, J2 & J6 Warranty

Allegra 6/GS-6/Spinchron n SeriesRotor Warranty

Allegra 21, Allegra 64, Avanti i 30, GS-15,and Sn Spinchron15 Series Rotor Warranty

Microfuge Series Rotor Warranty

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Page 3: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion
Page 4: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion
Page 5: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Concurrently with the computer modeling, our materialsand metallurgy laboratory conducts material propertystudies to determine which alloy and heat treatment touse. Composite materials may be used to reduce theweight of high-energy rotors, or to increase samplecapacity and rotor efficiency. To simulate conditions ofactual use, specimens of the alloys under consideration aresubjected to cyclic stress (or fatigue) testing. Tensilestrength tests, as well as metallographic analyses, areperformed on some sample forgings. Meanwhile,manufacturing and technology transfer engineers arereviewing the design for ease of manufacture.

Prototype rotors are then fabricated from the chosenalloy and tested by both nondestructive and destructivetest methods. In a specially constructed blockhouse, theprototypes are repeatedly cycled up to maximum speed toverify their design life. They are also intentionally run todestruction at the maximum speed attainable by the testcentrifuge. Videotapes of these single-cycle burst tests arereviewed to check the vertical and horizontal containmentof the rotor-centrifuge combination.

In the reliability lab, engineers load samples, assemble,and run the rotor to be sure no difficult or awkwardhandling methods are required. And our applicationsscientists use the prototype rotor to verify that it willachieve the particle separations it was designed for. Someof these tests may reveal the need for design changes. Inthat case, the rotor returns to the initial design stage andnew prototypes are made and submitted to the entire testcycle. When all criteria are met, the final design is turnedover to manufacturing for production.

Of course, rotors in production are also inspected asthey progress from the forging stage to finished product.As a final test of quality control, each rotor is balanced,run at the maximum rated speed, and its stability checkedbefore it is released for sale.

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Page 6: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Every High Performance and Benchtop p rotor alsoreceives a special “high stress test” to insure it will have along and safe life. This “high stress test” producesstresses that are far greater than the maximum possiblestresses to the rotor when you use it in your centrifuge.

Our confidence in these design and test proceduresenables us to warrant our rotors and centrifuges againstdefects in materials and workmanship. However, eachwarranty is based on the concept of a Beckman Coulter-designed and tested rotor/centrifuge system, in which thecharacteristics of the rotor, drive, instrument, andcontainment have been carefully matched to insure safeoperation conditions. Since it is impractical for us tosubject other manufacturers’ rotors and centrifuges to thetests just described, Beckman Coulter r does not warran t itsrotors when operating in other centrifuges, and does notwarrant its centrifuges when used with othermanufacturers ' rotors.

Using the proper rotor and centrifuge combinations willmeet the laboratory equipment standards and regulationsof UL, C-UL and CE Mark. Note that CE Markedinstruments must be used with the approved rotors to

maintain CEMarking -using otherrotor s willvoid the CEMarking.Refer to yourinstrumentmanual forthe approvedrotor list.

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Page 7: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion
Page 8: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion
Page 9: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

alloy will be exceeded: the rotor will not regain itsoriginal size and shape at the end of the run. Plasticdamage has occurred which may initiate a failure of therotor at some point. The maximum speed and sampledensity ratings designated by Beckman Coulter for eachrotor are intended to prevent this type of damage andshould always be observed.

Metal Fatigue - Any metal structure, following acertain number of stress cycles, will eventually sufferfatigue. When a rotor is repeatedly run up to operatingspeed and then decelerated, the cyclic stretching andrelaxing of the metal cause changes in its microstructure.Depending on how close to the elastic limit of the metalthe rotor is operated, and how many alternating stresscycles it experiences, these small changes will eventuallybecome microscopic cracks. With continued use, thecracks will enlarge, and failure of the rotor will ultimatelyoccur.

You may have noticed that Beckman Coulter provides adifferent type of warranty for its ultracentrifuge rotorsthan it does for its lower speed rotors. Metal fatigue is oneconsideration in determining these warranty provisions.To meet demanding operating requirements, manyultracentrifuge rotors are designed close to the elasticlimits of their alloys. Because these rotors may fail due tometal fatigue if used for more than a certain number ofruns or hours, the useful rotor lifetime is based on a lowernumber of years of usage then the J Series or BenchtopSeries rotors.

Rotors for lower speed centrifuges, such as theBeckman Coulter J6,J2 and Avanti J series, however, aredesigned to operate far below the elastic limits of theiralloys. Consequently, the useful lifetime on these rotors isa longer time period. See the table on the next page for anoverview on the warranty period and retirementrecommendations for each class of rotor.

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Page 10: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Warranty and Retirement Recommendations

Beckman Coulter rotor warranties are shown in full at the end ofthis booklet.

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Page 11: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Stress Corrosion Corrosion, the attack on metalsurfaces by moisture, chemicals, or alkaline solutionssuch as cesium chloride or other salts, is an aluminumrotor’s worst enemy (see Figure 3). The resultant pittingreduces the amount of metal available to bear stressduring operation at speed. When this occurs in a highlystressed area, the bottom of a cell hole in a fixed anglerotor, for example, the increased load on the remainingmetal results in a so-called stress concentrator. Repeateduse will cause cracks to develop, and failure of the rotorwill result.

This combination of stress and corrosion is called stresscorrosion. It will cause failure sooner and at a much lowerlevel of stress than if the rotor were undamaged bycorrosion. Stress corrosion is the primary cause of failureof aluminum rotors, especially as they age. Suggestionsfor avoiding; it are discussed in the next section.

Figure 3. Corroded Aluminum Rotor. A. Corrosion at bottom ofthe tube cavities may be visible when illuminated by penlight.B. Aluminum rotor cut away to show pitting at the bottom of tubecavities

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Page 12: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Proper Use and Maintenance

All rotors are designed to carry a maximum load at aspecific maximum speed. Since even one run made underconditions of excessive stress may significantly reduce thefatigue life of a rotor, it is important to abide by theoperational specifications published in each rotor manual.Speed reductions required for running high-densitysolutions, plastic adapters, or stainless steel tubes shouldalways be observed. Sample loads must be balanced andswinging bucket rotors must not be run with missingbuckets, and sample loads should be balanced. For therotors that utilize carbon-fiber composite cannisters, allcannisters must be used at all times, even if there is nobottle inside the cannister.

Each Beckman Coulter ultracentrifuge rotor carries anoverspeed disk that prevents it from exceeding itsmaximum rated speed through operator error orinstrument malfunction. But it is the user’s responsibilityto be sure that the correct disk is on the bottom of therotor, that the disk is in good condition, or that a speed-derating disk is installed if and when the warrantyconditions requires it. A well-kept rotor log is alsoessential for continued safe operation of anultracentrifuge.

Rotors for the Beckman Coulter J6 and J2 series ofcentrifuges, on the other hand, are protected fromdangerous single-cycle overspeed condition by windage orby the power limitations of the drive. The Avanti J seriescentrifuges have a rotor identification system, which useswindage/rotor inertia measurements or special magnets toautomatically limit the maximum speed setting of theinstrument. The centrifuge user should take care toprevent overspeeding by setting the proper run speed eachtime, because the fatigue life of the rotor will be reducedby this. Since these rotors are warranted for a specifictime period, it is not necessary to log their usage. The

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Page 13: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

purchase date of each rotor should be recorded, however,and kept on permanent file. Note that the purchase datemay be somewhat different from the manufacturing dateshown in the rotor serial number There is an expirationdate permanently marked on some rotors and rotoraccessories. The component must not be used beyond itsexpiration date under any circumstances.

Most rotors are fabricated from titanium or aluminumalloys, materials that have high strength-to-weight ratios.Titanium has another desirable characteristic: it is quiteresistant to corrosion. Aluminum is less expensive, but farmore susceptible to corrosion. If a rotor will be frequentlyused with corrosive salt solutions, such as cesium chlorideor potassium bromide, a titanium rotor may be a betterchoice. Note that even if the rotor is made from a titaniumalloy, other components, including lids, knobs, spacers,caps, and plugs may be made from aluminum alloysbecause of design considerations. These components arealso susceptible to corrosion and should be cared forfollowing the recommendations for aluminum rotors (seebelow).

All Beckman Coulter aluminum rotors are anodizedwith a thin coat of aluminum oxide that protects theunderlying metal as long as this oxide layer remainsunbroken. If it is scratched or otherwise damaged,however, corrosion will occur. Thus some precautionsmust be taken when cleaning these rotors after use.

First, rotor cavities and buckets must never be cleanedwith an ordinary bottle brush with sharp wire ends. Anycontact with these or other sharp instruments could easilydamage the anodized layer, creating a site for stresscorrosion to begin. Special plastic-coated brushesavailable from Beckman Coulter should be used instead.

Alkaline detergents or cleaning solutions, which mayremove the anodized coating, must be avoided. (Mostcommercially available solutions designed for radioactivedecontamination are highly alkaline.) A mild detergent*,

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Page 14: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

such as Beckman 555, will not attack the anodizedsurface. If corrosive materials have been run or spilled onthe rotor, wash it immediately. Particular care should betaken when aluminum swinging bucket rotors oraluminum fixed angle rotors have been used withuncapped tubes containing cesium chloride or other salts.Any salt crystals will corrode the metal unless carefullywashed away. Only the buckets of a swinging bucket rotorshould be washed. The body of the rotor should never beimmersed; the hanger mechanisms are hard to dry and canrust. After the rotor has been cleaned and thoroughlyrinsed with water, it should be air-dried with buckets orcavities upside down.

All fixed angle vertical tube and near-vertical tuberotors should be stored upside down, with the lids or plugsremoved. Swinging bucket rotors should be stored withthe bucket caps removed. Store all rotors in a dryenvironment, not in the centrifuge. Any moisture or othercontamination present during storage is a potential sourceof corrosion.

There are manuals* covering rotors and tubes forpreparative ultracentrifuges, tabletop ultracentrifuges, andJ2,J6 and Avanti J series centrifuges that every usershould read as well as the instruction manual thataccompanies each rotor. These publications coveroperation, cleaning lubrication, and storage in more detail.

*A list of suitable detergents is given in the Appendix A: ChemicalResistances in the following publications. This information is alsoavailable in Chemical Resistances, IN- 175. This list of commonlaboratory chemicals and their effect on rotor and tube materialsshould always be consulted if the possible interaction is in doubt.Rotors and Tubes for Preparative Ultracentrifuges,publication LR-IMRotors and Tubes for Tabletop Preparative Ultracentrifuges,publication TLR-IMRotors and Tubes for J 2 J6, and Avanti J Series Centrifuges,publication JR-IM

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Page 15: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

UltracentrifugeClassificationProgram

All Beckman Coulter ultracentrifuges are classified according to therotors that can be safely used in them. Rotor/ultracentrifugecompatibility is a function of the rotor chamber size, the type ofoverspeed protection, the kind of chamber door and barrier ring, andthe updating, if any, the ultracentrifuge has received. Before running arotor, check the classification decal on top of your instrument to besure it matches that of the rotor selected. This classification isstamped on the lid or top of all Beckman Coulter rotors.

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Page 16: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Field Rotor Inspection Program(FRIP)

This program has two purposes: to prevent prematurefailures by detection of stress corrosion, metal fatigue,wear or damage to anodized coatings, and to instructlaboratory personnel in the proper care of rotors. TheFRIP program is available to all owners of BeckmanCoulter J, Avanti J, L, TL, ML and Optima seriescentrifuges. Contact your local Beckman Coulter FieldService Office for arrangements.

At your request, a specially trained Beckman Coulterrepresentative will come to your lab and examine all yourrotors. Using nondestructive methods (fiber-opticsborescopy), they may find signs of corrosion or otherdamage. If so, they will recommend repair or replacement,and a potentially costly failure may be prevented.

A formal presentation is also given to provideinformation about maintenance procedures and rotordamage and its significance. The stress corrosion ofaluminum rotors, in particular, can be greatly reduced bygood laboratory practice.

Sometimes rotor corrosion is so bad it is easily visible tothe naked eye (see Figure 3). At other times, it is lessapparent. If you have doubt about the condition of a singleBeckman Coulter rotor, you may return it to the factory inPalo Alto, California or in Galway Ireland, where it willbe inspected free of charge. Before shipping the rotor, youmust contact the nearest Beckman Coulter office forspecific instructions. A written statement must accompanyeach rotor, indicating that it is safe to handle (free of anypathogenic or radioactive contamination).

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Page 17: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Out-of-Warranty Rotorsand Rotor Retirement

Every rotor, no matter how well designed or well caredfor, will someday reach the point where it may fail duringoperation. Metal fatigue, invisible to the naked eye, willhave taken its toll with every use. When the warrantyperiod has expired, consideration should be given to theretirement of the rotor.

Beckman Coulter ultracentrifuges are designed tocontain the physical destruction that results from themechanical failure of a Beckman Coulter rotor. However,the risk of losing valuable samples and severely damagingthe instruments makes the use of out-of-warranty rotors acostly gamble. Rotors used in Beckman Coulter J6,J2 andAvanti J series centrifuges have been designed and testedto insure a normal fatigue life that extends beyond thenumber of cycles thatcould ever be run duringthe 7-year warranty cycle.However, after manyyears of use, there willinevitably be somecorrosion or stresscorrosion. At some point,the combination of suchdamage and metal fatiguecould make the rotorvulnerable to a failure.Although a rotor mayappear to be in goodcondition, once thewarranty period has beenreached you shouldconsider retiring therotor. In all cases we urge

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Page 18: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

you to follow the rotor retirement recommendationsshown earlier in this document.

Some rotor components have a warranty period that isthe same as their expiration date. Because thesecomponents are highly stressed there is a strongpossibility that the component could fail with prolongeduse. It is essential that the component is taken out ofservice and retired once the expiration date has beenreached. Some of the components that have expirationdates include carbon-fiber cannisters, carriers and somelabware. The expiration date or manufacturing date isusually engraved or molded into the component. Refer tothe individual rotor bulletins for specific information onthe expiration dates.

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Page 19: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Special Warranty for Preparative Ultracentrifuge RotorsAll Beckman ultracentrifuge Fixed Angle, Vertical Tube, Near Vertical Tube,Swinging Bucket, and Airfuge rotors are warranted against defects in materials orworkmanship for the time periods indicated below, subject to the Warranty Conditionsstated below.Preparative Ultracentrifuge Rotors 5 years -- No ProrationAnalytical Ultracentrifuge Rotors 5 years -- No ProrationTL & ML Series Ultracentrifuge Rotors 5 years --No ProrationAirfuge Ultracentrifuge Rotors 1 year -- No ProrationFor Zonal, Continuous Flow, Component Test, and Rock Core ultracentrifuge rotors,see separate warranty.Warrantv Conditions (as applicable)

2)

3)

4)

5)

6)

This warranty is valid for the time periods indicated above from the date ofshipment to the original Buyer by Beckman or an authorized Beckmanrepresentative.This warranty extends only to the original Buyer and may not be assigned orextended to a third person without written consent of Beckman.This warranty covers the Beckman Centrifuge Systems only (including but notlimited to the centrifuge, rotor, and accessories) and Beckman shall not be liablefor damage to or loss of the user’s sample, non-Beckman tubes, adapters, or otherrotor contents.This warranty is void if the Beckman Centrifuge System is determined byBeckman to have been operated or maintained in a manner contrary to theinstructions in the operator’s manual(s) for the Beckman Centrifuge Systemcomponents in use. This includes but is not limited to operator misuse, abuse, ornegligence regarding indicated maintenance procedures, centrifuge and rotorclassification requirements, proper speed reduction for the high density of certainfluids, tubes, and tube caps, speed reduction for precipitating gradient materials,and speed reduction for high-temperature operation.Rotor bucket sets purchased concurrently with or subsequent to the purchase of aSwinging Bucket Rotor are warranted only for a term co-extensive with that ofthe rotor for which the bucket sets are purchased.This warranty does not cover the failure of a Beckman rotor in a centrifuge not ofBeckman manufacture, or if the rotor is used in a Beckman centrifuge that hasbeen modified without the written permission of Beckman, or is used withcarriers, buckets, belts, or other devices not of Beckman manufacture.Rotor parts subject to wear, including but not limited to rotor O-rings, VTi,NVTtm TLV, TLN, and MLN rotor tube cavity plugs and gaskets, tubing, tools,optical overspeed disks, bearings, seals, and lubrication are excluded from thiswarranty and should be frequently inspected and replaced if they become worn ordamaged.Keeping a rotor log is not mandatory, but may be desirable for maintenance ofgood laboratory practices.

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Page 20: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Repair and Replacement Policies1) If a Beckman rotor is determined by Beckman to be defective, Beckman will

repair or replace it, subject to the Warranty Conditions. A replacement rotor willbe warranted for the time remaining on the original rotor’s warranty.

2) If a Beckman centrifuge is damaged due to a failure of a rotor covered by thiswarranty, Beckman will supply free of charge (i) all centrifuge parts required forrepair (except the drive unit, which will be replaced at the then current price lessa credit determined by the total number of revolutions or years completed,provided that such a unit was manufactured or rebuilt by Beckman), and (ii) ifthe centrifuge is currently covered by a Beckman warranty or Full ServiceAgreement, all labor necessary for repair of the centrifuge.

3) If a Beckman rotor covered by this warranty is damaged due to a malfunction ofa Beckman ultracentrifuge covered by an Ultracentrifuge System ServiceAgreement, Beckman will repair or replace the rotor free of charge.

4) If a Beckman rotor covered by this warranty is damaged due to a failure of aBeckman tube, bottle, tube cap, spacer, or adapter, covered under the Conditionsof this Warranty, Beckman will repair or replace the rotor and repair theinstrument as per the conditions in policy point (2) above, and the replacementpolicy.

5) Damage to a Beckman rotor or instrument due to the failure or malfunction of anon-Beckman tube, bottle, tube cap, spacer, or adapter is not covered under thiswarranty, although Beckman will assist in seeking compensation under themanufacturer’s warranty.

DisclaimerIT IS EXPRESSLY AGREED THAT THE ABOVE WARRANTY SHALL BE INLIEU OF ALL WARRANTIES OF FITNESS AND OF THE WARRANTY OFMERCHANTABILITY AND BECKMAN SHALL HAVE NO LIABILITY FORSPECIAL OR CONSEQUENTIAL DAMAGES OF ANY KIND WHATSOEVERARISING OUT OF THE MANUFACTURE, USE, SALE, HANDLING, REPAIR,MAINTENANCE, OR REPLACEMENT OF THE PRODUCT.

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Page 21: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Special Warranty for Zonal, Continuous Flow, Component Test,and Rock Core Ultracentrifuge RotorsAll Beckman Zonal, Continuous Flow, Component Test, and Rock Coreultracentrifuge rotors are warranted against defects in materials or workmanship for2000 runs or 5 years (No Proration), whichever occurs first, subject to the WarrantyConditions stated below.

Warranty, Conditions (as applicable)1) This warranty is valid ‘for the time periods indicated above from the date of

shipment to the original Buyer by Beckman or an authorized Beckmanrepresentative.

2)

3)

4)

5)

6)

7)

8)

9)

This warranty extends only to the original Buyer and may not be assigned orextended to a third person without written consent of Beckman.This warranty covers the Beckman Centrifuge Systems only (including but notlimited to the centrifuge, rotor, and accessories) and Beckman shall not be liablefor damage to or loss of the user’s sample, non-Beckman tubes, adapters, or otherrotor contents.This warranty is void if the Beckman Centrifuge System is determined byBeckman to have been operated or maintained in a manner contrary to theinstructions in the operator’s manual(s) for the Beckman Centrifuge Systemcomponents in use. This includes but is not limited to operator misuse, abuse, ornegligence regarding indicated maintenance procedures, centrifuge and rotorclassification requirements, proper speed reduction for the high density of certainfluids, tubes, and tube caps, speed reduction for precipitating gradient materials,and speed reduction for high-temperature operation.Rock Core Rotor bucket sets purchased concurrently with or subsequent to thepurchase of a Rock Core Rotor are warranted only for a term co-extensive withthat of the rotor body for which the bucket sets are purchased.Rotor cores and liners purchased concurrently with or subsequent to the purchaseof a Zonal or Continuous Flow Rotor are warranted only for a term co-extensivewith that of the rotor for which the cores and liners are purchased.This warranty does not cover the failure of a Beckman rotor in a centrifuge not ofBeckman manufacture, or if the rotor is used in a Beckman centrifuge that hasbeen modified without the written permission of Beckman, or is used withcarriers, buckets, belts, or other devices not of Beckman manufacture.Rotor parts subject to wear, including but not limited to rotor O-rings, rotor tube-cavity plugs and gaskets, caps, tubing, tools, optical overspeed disks, bearings,seals, and lubrication are excluded from this warranty and should be frequentlyinspected and replaced if they become worn or damaged.Use of a log book or other means of determining rotor usage is required.

Repair and Replacement Policies1) If a Beckman rotor is determined by Beckman to be defective, Beckman will

repair or replace it, subject to the Warranty Conditions. A replacement rotor willbe warranted for the time remaining on the original rotor’s warranty.

2) If a Beckman centrifuge is damaged due to a failure of a rotor covered by thiswarranty, Beckman will supply free of charge (i) all centrifuge parts required forrepair (except the drive unit, which will be replaced at the then current price lessa credit determined by the total number of revolutions or years completed,provided that such a unit was manufactured or rebuilt by Beckman), and (ii) ifthe centrifuge is currently covered by a Beckman warranty or Full ServiceAgreement, all labor necessary for repair of the centrifuge.

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Page 22: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

3) If a Beckman rotor covered by this warranty is damaged due to a malfunction ofa Beckman ultracentrifuge covered by an Ultracentrifuge Full Service Agreementwith rotor coverage, Beckman will repair or replace the rotor free of charge.

4) If a Beckman rotor covered by this warranty is damaged due to a failure of aBeckman tube, bottle, tube cap, spacer, core, or adapter, covered under theConditions of this Warranty, Beckman will repair or replace the rotor and repairthe instrument as per the conditions in policy point (2) above, and thereplacement policy.

5) Damage to a Beckman rotor or instrument due to the failure, or malfunction of anon-Beckman tube, bottle, tube cap, spacer, or adapter, is not covered under thiswarranty, although Beckman will assist in seeking compensation under themanufacturer’s warranty.

DisclaimerIT IS EXPRESSLY AGREED THAT THE ABOVE WARRANTY SHALL BE INLIEU OF ALL WARRANTIES OF FITNESS AND OF THE WARRANTY OFMERCHANTABILITY AND BECKMAN SHALL HAVE NO LIABILITY FORSPECIAL OR CONSEQUENTIAL DAMAGES OF ANY KIND WHATSOEVERARISING OUT OF THE MANUFACTURE, USE, SALE, HANDLING, REPAIR,MAINTENANCE, OR REPLACEMENT OF THE PRODUCT.

Factory Rotor Inspection ServiceBeckman Coulter will provide free mechanical and metallurgical inspection in PaloAlto, California, USA, of any Beckman rotor at the request of the user. (Shippingcharges to Beckman Coulter are the responsibility of the user.) Rotors will beinspected in the user’s laboratory if the centrifuge in which they are used is covered byan appropriate Beckman Coulter Service Agreement. Contact your local BeckmanCoulter office for details of service coverage or cost.

Before shipping, contact the nearest Beckman Coulter Sales and Service office andrequest a Returned Goods Authorization (RGA) form and packaging instructions.Please include the complete rotor assembly, with buckets, lid, handle, tube cavity caps,etc. A SIGNED STATEMENT THAT THE ROTOR AND ACCESSORIES ARENON-RADIOACTIVE, NON-PATHOGENIC, NON-TOXIC, AND OTHERWISESAFE TO SHIP AND HANDLE IS REQUIRED.

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Page 23: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Special J Series Rotor WarrantySubject to the conditions specified below and the warranty clause of the BeckmanCoulter terms and conditions of sale in effect at the time of sale, Beckman Coulteragrees to correct either by repair, or, at its election, by replacement, any defects ofmaterial or workmanship which develop within seven (7) years after delivery of a Jseries rotor to the original buyer by Beckman Coulter or by an authorizedrepresentative, provided that investigation and factory inspection by Beckman Coulterdiscloses that such defect developed under normal and proper use. Should a BeckmanCoulter centrifuge be damaged due to a failure of a rotor covered by this warranty,Beckman Coulter will supply free of charge all centrifuge parts required for repair.

ReplacementAny product claimed to be defective must, if requested by Beckman Coulter, bereturned to the factory, transportation charges prepaid, and will be returned to Buyerwith the transportation charges collect unless the product is found to be defective, inwhich case Beckman Coulter will pay all transportation charges.

A defective rotor will be replaced by Beckman Coulter at its then current list price lessa credit based upon the age of the rotor (years since date of purchase). The Buyer shallnot receive credit until the claimed defective rotor is returnedto Beckman Coulter’sCentrifuge Development Center at Palo Alto, California, or delivered to a BeckmanCoulter Field Service representative.

The replacement price (cost to Buyer) for the respective rotor shall be calculated asfollows:

Conditionsyears

Replacement price = Current rotor list price x -7

1. Except as otherwise specifically provided herein, this warranty covers the rotoronly and Beckman Coulter shall not be liable for damage to accessories orancillary supplies including but not limited to (I) tubes, (ii) tube caps, (iii) tubeadapters, or (iv) tube con tents.

2. This warranty is void if the rotor has been subjected to customer misuse such asoperation or maintenance contrary to the instructions in the Beckman Coulterrotor or centrifuge manual.

3. This warranty is void if the rotor is operated with a rotor drive unit or in acentrifuge unmatched to the rotor characteristics, or is operated in a Beckmancentrifuge that has been Improperly disassembled, repaired, or modified.

DisclaimerIT IS EXPRESSLY AGREED THAT THE ABOVE WARRANTY SHALL BE INLIEU OF ALL WARRANTIES OF FITNESS AND OF THE WARRANTY OFMERCHANT-ABILITY AND THAT BECKMAN COULTER SHALL HAVE NOLIABILITY FOR SPECIAL OR CONSEQUENTIAL DAMAGES OF ANY KINDWHATSOEVER ARISING OUT OF THE MANUFACTURE, USE, SALE,HANDLING, REPAIR, MAINTENANCE, OR REPLACEMENT OF THEPRODUCT.

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Page 24: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Allegra 21 Series, Allegra 64, Avanti 30, GS-15 Series, and Spinchron 15Series Rotor WarrantySubject to the condihons specified below and the warranty clause of the Beckman terms andconditions in effect at the time of sale, Beckman agrees to correct either by repair, or, at its election,by replacement, any defects of material or workmanship which develop within one (I) year afterdelivery of an Allegra 21 series, Allegra 64, Avanti 30, GS-15 series, o r Spinchron 15 seriescentrifuge rotor to the original buyer by Beckman o r by an authorized representative, provided thatInvestigation and factory inspection by Beckman discloses that such defect developed under normaland proper use Should a Beckman centrifuge be damaged due to a failure of a rotor covered by thiswarranty, Beckman will supply free of charge all centrifuge parts require for repairConditions1. Except as otherwise specifically provided herein, this warranty covers the rotor only and

Beckman shall not be liable for damage to accessories or ancillary supplies including but notlimited to (I) tubes, (ii) tube caps, (iii) tube adapters or (iv) tube contents.

2 This warranty is void if the rotor has been subjected to customer misuse such as operation ormaintenance contrary to the instructions in the Beckman rotor or centrifuge manual.

3. This warranty is void if the rotor is operated with a rotor drive unit or in a centrifugeunmatched to the rotor characteristics, or is operated in a Beckman centrifuge that has beenimproperly disassembled repaired or modified

4. Rotor bucket sets purchased concurrently with or subsequent to the purchase of a horizontalrotor are warranted only for a term coextensive with that of the rotor for which the bucket setsare purchased.

DisclaimerIT IS EXPRESSLY AGREED THAT THE ABOVE WARRANTY SHALL BE INLIEU OF ALL WARRANTIES OF FITNESS AND OF THE WARRANTY OFMERCHANT-ABILITY AND THAT BECKMAN SHALL HAVE NO LIABILITYF O R S P E C I A L O R C O N S E Q U E N T I A L D A M A G E S O F A N Y K I N DW H A T S O E V E R A R I S I N G O U T O F T H E M A N U F A C T U R E , U S E , S A L E ,H A N D L I N G , R E P A I R , M A I N T E N A N C E , O R R E P L A C E M E N T O F T H E

PRODUCT.

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Page 25: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Microfuge Series Rotor WarrantySubject to the conditions specified below and the warranty clause of the Beckman terms andconditions in effect at the time of sale, Beckman agrees to correct either by repair or, at its election,by replacement, any defects of material or workmanship which develop within one (I) year afterdelivery of a Microfuge @ series centrifuge rotor to the angina1 buyer by Beckman or by anauthorized representative, provided that investigation and factory inspection by Beckman disclosesthat such defect developed under normal and proper use. Should a Beckman centrifuge be damageddue to a failure of a rotor covered by this warranty, Beckman will supply free of charge all centrifugeparts required for repair.CONDITIONS1. Except as otherwise specifically provided herein, this warranty covers the rotor only and

Beckman shall not be liable for damage to accessories or ancillary supplies Including but notlimited to (i) tubes, (II) tube caps, (iii) tube adapters, or (iv) tube contents.

2. This warranty is void if the rotor has been subjected to customer misuse such as operation ormaintenance contrary to the instructions in the Beckman rotor or centrifuge manual.

3 This warranty IS void if the rotor is operated with a rotor drive unit or in a centrifugeunmatched to the rotor characteristics or operated in a Beckman centrifuge that has beenImproperly disassembled, repaired, or modified.

4. Rotor bucket sets purchased concurrently with or subsequent to the purchase of a horizontalrotor are warranted only for a term coextensive with that of the rotor for which the bucket setsare purchased.

DISCLAIMERIT IS EXPRESSLY AGREED THAT THE ABOVE WARRANTY SHALL BE IN LIEU OF ALLWARRANTIES OF FITNESS AND OF THE WARRANTY OF MERCHANTABILITY ANDTHAT BECKMAN SHALL HAVE NO LIABILITY FOR SPECIAL OR CONSEQUENTIALDAMAGES OF ANY KIND WHATSOEVER ARIS ING OUT OF THE MANUFACTURE, USE,SALE, HANDLING, REPAIR, MAINTENANCE, OR REPLACEMENT OF THE PRODUCT

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Page 26: Ultracentrifuge Classification Programuse will cause cracks to develop, and failure of the rotor will result. This combination of stress and corrosion is calle d stress corrosion

Beckman Coulter, Inc.4300 N. Harbor Blvd, Box 3 100 - Fullerton, California 92834-3 100

Sales: I-800-742-2345 - Service: 1-800-551-1150 - Fax: l-800-643-4366Internet: http://www.beckmancoulter.com - Telex: 768413

CISDC-1298

DS-625-C

1998 Beckman Coulter, lnc