Temple University’s School of Pharmacy (TUSP) offers a dynamic curriculum taught byacademic and industry experts who teach the most progressive advances in the field.

Our graduate programs foster a deep understanding and practical application of keydisciplinary principles, including

• drug action (pharmacodynamics),• drug synthesis (medicinal chemistry),• drug metabolism and disposition (pharmacokinetics, metabolism, and genetic predisposition),• drug delivery (pharmaceutics),• drug regulation, quality, and safety (quality assurance/regulatory affairs).

At TUSP students experience a multidisciplinary approach to learning, which blends classroomteaching, laboratory research, and experiential learning in the epicenter of the East Coast’spharmaceutical industry. Our courses expose students to every aspect of the discovery, action,utilization, and evaluation of therapeutic agents, helping them to develop into promisingresearch scientists or professionals in industry or academia.

Career OpportunitiesA graduate degree in pharmaceutical sciences opens the doors for a variety of careeropportunities. Many TUSP graduates have pursued research and regulatory careers in thepharmaceutical industry (including Pfizer, Merck, Bristol-Myers Squibb, AstraZeneca,Novartis, Boehringer-Ingelheim, and numerous other companies). Other graduates haveaccepted faculty or postdoctoral positions at top academic institutions (including HarvardUniversity, Washington University, Fox Chase Cancer Center, Florida A&M University, andTufts University). Others have sought careers in the government, including the U.S. Food andDrug Administration.

TUSP has emerged

as one of the most

vibrant centers of

education and

research in the

pharmaceutical

sciences in the

Philadelphia

region.

Graduate Programs in the Pharmaceutical Sciences

For more information: Dr. Daniel Canney, Director of Graduate StudiesTemple University School of PharmacyPharmaceutical Sciences Department3307 North Broad Street, Suite 520BPhiladelphia, PA 19140 USAEmail: phscgrad@temple.eduPhone: 215.707.4948 • Fax: 215.707.5620www.temple.edu/pharmacy/programs/Graduate.html

Programs

Faculty Research Interests

Choose from thesis-based or non-thesis based degree programs:

THESIS-BASED PROGRAMS (MS or PhD)These full-time programs lead to an MS (30 didactic and 6 research credits)or PhD (40 didactic and 12 research credits) in:

• Medicinal Chemistry/Drug Discovery• Pharmaceutics• Pharmacodynamics

Thesis-based MS and PhD students pursue courses and research full-timeat the Pharmacy School, using resources of the University’s Health ScienceCampus, including Temple University’s Hospital, Medical and DentalSchools, College of Health Professions, and School of Podiatric Medicine. In-depth research may be pursued at the Pharmacy School’s unique facilities,including:

• the Moulder Center for Drug Discovery Research• the Jayne Haines Center for Pharmacogenomics and Drug Safety• the Laboratory for Bioanalysis and Pharmacokinetics• the cGMP Facility.

Breakthroughs are explored in many areas, including cancer, AIDS, diabetes,Alzheimer’s, and the human genome. The curriculum integrates three mainareas of pharmaceutical science: medicinal chemistry, pharmaceutics, andpharmacodynamics.

Financial support in the form of teaching assistantships, research assistant-ships, and University Fellowships is available on a competitive basis to in-coming PhD students.

NON-THESIS BASED PROGRAMS (PART-TIME MS)Designed for working professionals, these part-time programs lead to an MSdegree (36 credits). Certificates (12 – 15 credits) are also available.

• Non-thesis MS in Pharmaceutics• MS in Quality Assurance/Regulatory Affairs (QA/RA)

Pharmaceutics courses are taught by TUSP graduate faculty and industryexperts in drug discovery and development, regulatory affairs, manufacturingand validation. Courses are conveniently scheduled on weeknights and week-ends and can be videoconferenced to corporate sites nationally and interna-tionally. Some courses are also available online.

Non-Thesis MS in Pharmaceutics: Addressing the needs of highly-skilled,technically-trained professionals with undergraduate or graduate sciencebackgrounds, the Non-Thesis MS helps pharmacists, bench scientists, andlaboratory technicians to expand career opportunities. Courses in QualityAssurance/Regulatory Affairs (QA/RA) blend the pharmaceutical scienceswith the industry’s regulatory milieu. Learning advanced pharmaceuticalsciences enables students to make valuable contributions to company projectswhile being cognizant of regulatory requirements.

A four-course certificate is available.

Non-thesis MS in QA/RA: Temple University’s School of Pharmacy pio-neered the first graduate curriculum in QA/RA in the world in 1968. Overthe last four decades, the School has fostered a strong relationship with theU.S. FDA and pharmaceutical industry. The QA/RA curriculum features over60 courses on the latest quality practices and regulatory principles for begin-ning, mid-level, and veteran industry and FDA officials. The program isdelivered locally, nationally, and internationally.

Eight certificates are available.

For additional information, please refer to the separate brochure on the QA/RAprogram or visit www.temple.edu/pharmacy_QARA.

Drug design, discovery, and lead optimization, including:Synthesis of small molecule therapies in multiple diseases as lead drug candidates and as chemical probes to test biological hypotheses;Structure Activity Relationships (SAR) studies involving ligands forpharmacologically relevant targets; selective enzyme inhibitors/activators; investigation of disease areas (such as neurodegenerative diseases, epilepsy, Alzheimer’s); and bio-organic/medicinal chemistry at membrane interfaces.

Screening methodologies and assay development for drug discovery, including:Cellular/molecular markers; allosteric modulators and biased ligandsof G-protein coupled receptors; and molecular pharmacology.

Human pharmacokinetic predictions, including:Drug and xenobiotic metabolism; new technology platforms for multifunctional therapeutics

Role of pharmacogenetics in inter-individual variability of drug response, disease risk and incidence, including:Genetic polymorphism of drug-metabolizing enzymes; genotype-phenotype associations; and drug targets that determine variationsin drug response.

Formulation and development aspects of drug delivery systems based on drugs’ physical-chemical properties, including:Design of modified and novel drug delivery systems; nonomedicineto improve therapeutic efficiency of anticancer compounds; biopharmaceutics; and novel drug/gene delivery systems.

Theoretical pharmacology, including:Thermodynamics of drug-receptor interactions; synergistic drug interactions; opioid analgesics: evaluation, tolerance and dependence;pharmacological basis underlying preclinical effects of opioids,hallucinogens, antidepressants, antiobesity agents and antipsychotics;and behavioral pharmacology of opioids, serotonergics, chemotherapeutics, and cannabinoids.