The new dyspepsia MPharm module at  Nottingham

 

Cristina De Matteis & Helen Boardman

Innovation in Pharmacy Education DivisionSchool of Pharmacy

 

Integrating science and clinical practice, and context-based

teaching of science

 

Semester 1 Semester 2

Year 1Transition to Higher Education and the

Pharmacy ProfessionDrug, Medicine and Patient Integrated

Modules (DMP)

Year 2Drug, Medicine and Patient Integrated

Modules (DMP)Drug, Medicine and Patient Integrated

Modules (DMP)

Year 3Drug, Medicine and Patient Integrated

Modules (DMP)Research and Broadening Horizons

Year 4Advanced Studies in Clinical

Pharmacy, Pharmacy Practice and Science

Advanced studies in Clinical Pharmacy, Pharmacy Practice and

Science

Drug, Medicine and Patient Integrated Modules (DMPs) Focus is on a disease state or organ system

Dyspepsia

Drug, medicine and patient modules

Seven pharmacy subject areas (the vertical themes)

Pharmacology & Therapeutics Clinical & Pharmacy Practice

Biology & Physiology Professionalism & Leadership

Pharmaceutics

Chemistry

Absorption, Distribution, Metabolism & Elimination (ADME)

Drug, medicine and patient modules

MPharm 2012: Dyspepsia (B31DYS) Summary of the vertical themes

Pharmacology &

Therapeutics

Biology & Physiology

Pharmaceutics

Chemistry

Absorption, Distribution, Metabolism

and Elimination

Clinical and Pharmacy Practice

Professionalism and Leadership

Diseases and Symptoms

• Causes of ‘chest pain’

• The process of peptic ulceration

• Drug (especially NSAID)-induced

Anatomy and Function of the Human Body

Structure & function of the stomach & GI tract

Physiology/ biology of parietal cells

Digestion

Physical & Chemical Proper- ties Relevant to Formulation

Solubility and solutions

Suspensions pH and its

impact on solubility, partition and

Mechanism of Drug Action Antacids Raft-forming

agents Antiflatulants PPIs

Fundamental Concepts Further

molecular structure,

Absorption Local and

systemic effects of drugs (e.g. antacids vs PPIs)

Acid/base effects, buffers, ionisation, pH partition,

Responding to symptoms of dyspepsia

Differential diagnosis

Health promotion advice with dyspepsia. Role of diet & lifestyle in

Personal Development and Professionalism Communication

skills Reinforcement

of calculations Reinforcement

of CPD opportunities

Start of

Drug, medicine and patient modules

MPharm 2012: Dyspepsia (B31DYS) Summary of the vertical themes

Pharmacology &

Therapeutics

Biology & Physiology

Pharmaceutics

Chemistry

Absorption, Distribution, Metabolism

and Elimination

Clinical and Pharmacy Practice

Professionalism and Leadership

Diseases and Symptoms

• Causes of ‘chest pain’

• The process of peptic ulceration

• Drug (especially NSAID)-induced

Anatomy and Function of the Human Body

Structure & function of the stomach & GI tract

Physiology/ biology of parietal cells

Digestion

Physical & Chemical Proper- ties Relevant to Formulation

Solubility and solutions

Suspensions pH and its

impact on solubility, partition and

Mechanism of Drug Action Antacids Raft-forming

agents Antiflatulants PPIs

Fundamental Concepts Further

molecular structure,

Absorption Local and

systemic effects of drugs (e.g. antacids vs PPIs)

Acid/base effects, buffers, ionisation, pH partition,

Responding to symptoms of dyspepsia

Differential diagnosis

Health promotion advice with dyspepsia. Role of diet & lifestyle in

Personal Development and Professionalism Communication

skills Reinforcement

of calculations Reinforcement

of CPD opportunities

Start of

Week 19 Week 20 Week 21 Week 22 Weeks 29 (& 34)Group A-F Group G-M Group N-T Group U-Z Group 1 Group 2 Group 3 Group 4 Group 1 Group 2 Group 3 Group 4 Group 1 Group 2 Group 3 Group 4 Group 1 Group 2 Group 3 Group 4

Monday9.009.30

10.0010.3011.0011.3012.0012.30

1.001.302.002.303.003.304.004.30

Tuesday9.009.30

10.0010.3011.0011.3012.0012.30

1.001.302.002.303.003.304.004.30

Wednesday9.009.30

10.0010.3011.0011.3012.0012.30

1.001.302.002.303.003.304.004.30

Thursday9.009.30

10.0010.3011.0011.3012.0012.30

1.001.302.002.303.003.304.004.30

Friday9.009.30

10.0010.3011.0011.3012.0012.30

1.001.302.002.303.003.304.004.30

Pharmacology revision lecture (MR)

Chemistry revision lecture (CDeM)

Pharmaceutics revision lecture (MA)

ADME (MR 3)

Biology revision lecture (SW)Triple therapy wkshop

Pract 5 - Dispensing

Triple therapy wkshop

Pract 5 - Dispensing

Chem wkshop Pract 4

CDeM 8

Chem wkshop

CDeM 10

Pract 5 -Dispensing

Triple therapy wkshop

Module review lecture

Case study 3 debrief

Triple therapy wkshop

Case study 3 workshop

Assessment

Lectures

Practicals

Workshops

PAR tutorial

Chem wkshop

SW 4

Pract 4

Practice revision lecture (HB)

MR 7

HB (Prof & leadership 1)

Chem wkshop

CDeM 11

HB (Prof & leadership 3)

Pract 5 - Dispensing

HB (Prof & leadership 4)

Case study 3 workshop

ADME (MR 2)

Module surgery session

ADME (MR 1)

SW 2

MR 5

CDeM 4

Pract 3

CDeM 9

MA 8

Module surgery sessionPreparation for practicals 2

Rogo

MA 6

HB (Clinical pract 4)

MA 7

R to S wkshop

R to S wkshop

SW 3

Pract 1 Pract 1 Pract 2

Case study 1 workshop

Introduction to case study 1

MR 4

Case study 2 debrief & case study 3 intro

CDeM 7

MA 4 (with CDeM 5)

Pract 1 Pract 1

Pract 2

MR 6

MA 5

R to S wkshop

Case study 1 workshop

Introduction to B31DYS

MR 3

CDeM 1

MR 1

MA3

MA 2

HB (Clinical pract 3) (with MR)

Case study 1 debrief & case study 2 intro

CDeM 3

HB (Clinical pract1)

MR 2

MA 1

Case study 2 workshop

R to S wkshop

Preparation for practicals

CDeM 6

PAR tutorial 4 - discussing exam results

SJB (Prof & leadership 2)

Pract 3

CDeM 2

HB (Clinical pract 2)

SW 1

B31DYS summary timetable (you must check the University timetable for the defintive version, and for information about groups)

Further dyspepsia revision (all) - WEEK 34

Case study 2 workshop

Assessment

Lectures

Practicals

Workshops

PAR tutorial

Narrative

Week 1

Week 2

Week 3

Week 4

Antacids/alginate

Antacids/alginate

H2RAs & PPIs

Complex scenariosH. pylori infection

NSAID induced ulceration

Drug based narrative

Incr

ease

d co

mpl

exity

Joint lectures

D4/E5 Medicines: physicochemical properties

Morgan Alexanderand

Cristina De Matteis

Joint Lecture

To explore

• A multidisciplinary concept • As used in ADME, chemistry and pharmaceutics• Henderson - Hasselbalch equation• Horizontal integration

Different subject areas have different ways of looking at things i.e. different intellectual cultures

Highlighting links

Proton pump inhibitors

Omeprazole

Today

9am E9. Chemistry of omeprazole

10am D8. Enteric coatings

1pm C4. Biology and omeprazole

The chemistry of drug action

HN

NS

N

OOO

Sharing slide material

– visually and verbally

Manufacturing antacids

Measuring the neutralising capacity of your medicine

Raft forming ability

Raft forming ability

calcium cation

alginic acid chain

Active ingredients:

Sodium alginate

Sodium bicarbonate

Calcium carbonate

Case studies

Student feedback

“I really like how the module integrates the science with the clinical part of pharmacy and applies the science to pharmacy practice, which makes everything we learn feel important and relevant”.

“I liked the case studies because it enhanced my understanding of dyspepsia. I liked how all the lectures interlink.”

“(I have) lots of interest in this module because it clearly focuses on dyspepsia, so the points are connected, and I can understand it. “

Integration

Context-based teaching of science

Threshold concepts

Multidisciplinarity

Employability

Acknowledgements

Course development team (UK and Malaysia)

Dyspepsia module design team (UK and Malaysia)