symposium on tumour heterogeneity · 2019-10-17 · transcan-2 presenting the projects from the...
TRANSCRIPT
ERA-NET: Aligning National/Regional Translational Cancer Research Programmes and Activities - TRANSCAN-2
Presenting the projects from the Joint Transnational Call 2014 co-funded by the European Commission on the topic of “Translational research on human tumour heterogeneity to overcome recurrence and resistance to therapy”
SYMPOSIUM ONTUMOUR HETEROGENEITY
Palazzo Pirelli, Milan
October 24th
2019
08:00 Registration
09:00 Welcome address by Marina Gerini, General Director Fondazione Regionale per la Ricerca Biomedica
09:10 Overview of TRANSCAN and JTC2014 (EC co-funded) Silvia Paradisi, National Institute of Health, Italy
Presentations of JTC 2014 projects co-funded by the EC
FIRST SESSIONChair: Ulrich Pfeffer, IRCCS Ospedale Policlinico San Martino, Italy
9:20 Targeting of resistance in pediatric oncology (TORPEDO) Jan Molenaar, Princess Maxima Center, The Netherlands
9:40 Overcoming neuroblastoma tumour heterogeneity, resistance and recurrence (ONTHETRRAC) Peter Ambros, Children’s Cancer Research Institute, Austria
10:00 Dissecting phenotypic heterogeneity of human melanoma: building a rationale for active immunotherapies overcoming immunologically-induced dedifferentiation (ITEM) Massimo Guidoboni, IRCCS IRST, Italy
10:20 Cancer evolution and identification of relapse-initiating cells (CEVIR) Christoph Klein, Ludwig-Maximilians - Universität Munich, Germany
11:40 Coffee break
Program
SECOND SESSION Chair: Atanasio Pandiella, Centro de Investigación del Cáncer, CSIC, Spain
11:10 Fighting resistance in CLL (FIRE-CLL) Eric Eldering, Academic Medical Center Department of Experimental Immunology, Amsterdam, Netherlands
11:30 Genetic and cellular intratumour heterogeneity as predictor of chronic lymphocytic leukemia outcome and treatment resistance (GCH-CLL) Olivier Bernard, Institut Gustave Roussy, France
11:50 Defeating recurrence and resistance in AML: Multigenomic approaches to analyse heterogeneity (DRAMA) Saverio Minucci, Istituto Europeo di Oncologia, Milan, Italy
12:10 Multiple myeloma intra-clonal heterogeneity: evolution and implications of targeted therapy (IntraMMclo) Jana Jakubikova, Cancer Research Institute SAS, Slovakia
12:30 Lunch
THIRD SESSIONChair: Peter Devilee, Leiden University, The Netherlands
13:30 Approaching recurrence and resistance mechanisms in esophagogastric adenocarcinomas from the prospective MEMORI trial (ARREST) Liam McDonnell, Fondazione Pisana per la Scienza ONLUS, Pisa, Italy
13:50 Targeting colon tumour initiating cell heterogeneity (TACTIC) Jan Paul Medema, Academic Medical Center/LEXOR, University of Amsterdam, The Netherlands
14:10 Evolution of resistant clones to novel target-directed drugs in colorectal tumours. A genetic and epigenetic study of intraTumoural heterogeneity dynamics (INTRACOLOR) Héctor G. Palmer, VHIO, Barcelona, Spain
14:30 Patient-derived models for intratumour functional heterogeneity and its implications for personalized medicine (BeFIT) Huei-Wen Chen, National Taiwan University, Taipei
14:50 Poster session
FOURTH SESSION Chair: Rolf Skotheim, Oslo University Hospital, Norway
16:20 Intratumour heterogeneity, clonal selection and metastatic propensity in breast cancer (HetMet) Stian Knappskog, University of Bergen, Norway
16:40 Clinical utility of tumour heterogeneity in triple negative breast cancer and high-grade serous ovarian carcinoma for prediction of therapy response (TH4RESPONS) Manfred Dietel, Institute of Pathology, Charité University Hospital Berlin, Germany
17:00 Proteogenomic and targeted metabolomic analysis of ovarian cancer heterogeneity and its contribution to recurrence and therapy resistance (PROMETOV) Christiane A. Opitz, German Cancer Research Center, Germany
17:20 Discussion: The impact and added value of transnational collaborations on cancer research Chairs: Hubert Misslisch, DLR, Germany and Jennifer Barrett, University of Leeds, UK
18:20/20:00
Networking dinner and poster prize ceremony
Organizing committee: Dr. Liron Even-Faitelson, Chief Scientist Office, Israeli Ministry of Health, [email protected]
Dr. Eva Batista, Ministry of Education, Science and Sport, Slovenia, [email protected]
Dr. Silvia Paradisi, National Institute of Health, Italy
Ms. Chiara Consonni, Fondazione Regionale per la Ricerca Biomedica, Italy
Ms. Carmen De Francesco, Fondazione Regionale per la Ricerca Biomedica, Italy
Ms. Maria Romero, Ministry of Health, Italy
The event is hosted by Regione Lombardia with the collaboration of Fondazione Regionale per la Ricerca Biomedica
PARTICIPATION IS FREE OF CHARGE Please register online by October 3rd: https://forms.gle/Dg4knLwNLeU66kJe8)
This project has received funding from the European Union’s Horizon 2020 Research and Innovation Programme under grant agreement No 643638