supplemental appendix 4

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Supplemental appendix 4 EXAMPLES OF BLEEDING MANIFESTATIONS* Skin domain: slides 2 to 23 Mucosal domain: slides 24 to 30 Organ domain: slides 31 to 32 not otherwise specified, pictures are taken from patients with prim

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Supplemental appendix 4. EXAMPLES OF BLEEDING MANIFESTATIONS*. Skin domain: slides 2 to 23 Mucosal domain: slides 24 to 30 Organ domain: slides 31 to 32. *Where not otherwise specified, pictures are taken from patients with primary ITP. Actual scale:. 1 cm. 2 cm. 3 cm. - PowerPoint PPT Presentation

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Page 1: Supplemental appendix 4

Supplemental appendix 4

EXAMPLES OF BLEEDING MANIFESTATIONS*

Skin domain: slides 2 to 23Mucosal domain: slides 24 to 30Organ domain: slides 31 to 32

*Where not otherwise specified, pictures are taken from patients with primary ITP

Page 2: Supplemental appendix 4

1 cm 2 cm 3 cmActual scale:

Courtesy by M. Michel

A crop of scattered petechiae

Page 3: Supplemental appendix 4

Courtesy by F. Rodeghiero

Purpuric manifestations in a patient with septicemia and thrombocytopenia

Page 4: Supplemental appendix 4

Courtesy by F. Rodeghiero

Allergic (maculopapular) skin reaction secondary to cephalosporin (should not be recorded)

Page 5: Supplemental appendix 4

Courtesy by M. Michel

Recent scattered petechiae with confluence to form a purpuric macule (arrow)

Page 6: Supplemental appendix 4

Courtesy by F. Rodeghiero

Synchronous recent scattered petechiae. Abrupt presentation in ITP

Page 7: Supplemental appendix 4

Courtesy by F. Rodeghiero

Same patient. Synchronous recent scattered petechiae extending to the sole.

Page 8: Supplemental appendix 4

Courtesy by F. Rodeghiero

Petechiae of various size and age

Page 9: Supplemental appendix 4

Courtesy by F. Rodeghiero

Palpable purpura in a non thrombocytopenic patient

Page 10: Supplemental appendix 4

Courtesy by R. StasiPetechiae and one ecchymosis larger than a patient’s palm size

Page 11: Supplemental appendix 4

Six reddish-purple ecchymoses smaller than a patient’s palm size

Courtesy by M. Michel

Page 12: Supplemental appendix 4

Courtesy by M. Michel

Leg ecchymoses and scattered petechiae (not recent)

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Courtesy by M. Michel

Several ecchymoses, one larger than patient’s palm size and no petechiae

Page 14: Supplemental appendix 4

Courtesy by F. Rodeghiero

Old ecchymosis, dating more than 10-15 days and a small, recent one

Page 15: Supplemental appendix 4

Courtesy by F. Rodeghiero

Extensive ecchymosis with underlying subcutaneous hematoma

Page 16: Supplemental appendix 4

Courtesy by F. Rodeghiero

Simmetrical ecchymoses with underlying subcutaneous hematomas caused by self-administered LMWH in a patient with ITP and moderate thrombocytopenia (should not be recorded)

Page 17: Supplemental appendix 4

Courtesy by F. Rodeghiero

Three old synchronous large ecchymoses and a few more recent petechiae

Page 18: Supplemental appendix 4

Courtesy by F. Rodeghiero

Ecchymoses of various age

Page 19: Supplemental appendix 4

Courtesy by F. Rodeghiero

Bullae and discoloration of skin not due to ITP (should not be recorded)

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Courtesy by F. RodeghieroVaste ecchymosis secondary to constriction

Page 21: Supplemental appendix 4

Courtesy by F. Rodeghiero

Old small ecchymoses (sometimes seen in healthy people, purpura simplex)

Page 22: Supplemental appendix 4

Courtesy by F. Rodeghiero

An old ecchymosis

Page 23: Supplemental appendix 4

Courtesy by F. Rodeghiero

Very old ecchymosis (weeks) and some more recent petechiae

Page 24: Supplemental appendix 4

Courtesy by M. Michel

Hemorrhagic bullae of various age, two 1-day old on the left tongue margin

Page 25: Supplemental appendix 4

Courtesy by M. Michel

Hemorrhagic bullae of various age, two 1-day old on the left tongue margin

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Courtesy by M. Michel

Old (2-3 days) hemorrhagic bullae and facial petechiae of various age

Page 27: Supplemental appendix 4

Courtesy by F. RodeghieroRecent hemorrhagic bullae (less than 2 days)

Page 28: Supplemental appendix 4

Courtesy by F. Rodeghiero

Sublingual recente ecchymosis

Page 29: Supplemental appendix 4

Partial hemorrhage in one eye and small peripalpebral ecchymosis in a patient with post-chemotherapy trombocytopenia

Courtesy by F. Rodeghiero

Page 30: Supplemental appendix 4

Bilateral peripalpebral ecchymoses and complete subconjunctival hemorrhage in a patient with post-chemotherapy trombocytopenia

Courtesy by F. Rodeghiero

Page 31: Supplemental appendix 4

Courtesy by M. Michel

Intracerebral hemorrage

Page 32: Supplemental appendix 4

Pictorial Blood Assessment Chart

In Rodeghiero et al, Haemophilia 2008; 14:68-75

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