sudden death, the anniversary effect ivan mendoza, juan marques, federico moleiro, ivan mendoza-b.,...

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SUDDEN DEATH, THE SUDDEN DEATH, THE ANNIVERSARY EFFECT ANNIVERSARY EFFECT Ivan Mendoza , Juan Marques, Federico Ivan Mendoza , Juan Marques, Federico Moleiro, Ivan Mendoza-B., Francesca Moleiro, Ivan Mendoza-B., Francesca Misticchio Misticchio Experimental Cardiology, Central Experimental Cardiology, Central University of Venezuela, Albert Einstein University of Venezuela, Albert Einstein Medical Center, Philadelphia, USA Medical Center, Philadelphia, USA Background: Background: Sudden death (SD) is one of the Sudden death (SD) is one of the major problems of public health and responsible major problems of public health and responsible for nearly half of all cardiac deaths. A better for nearly half of all cardiac deaths. A better understanding of the trigger mechanism will have understanding of the trigger mechanism will have an important preventive impact. Recently an important preventive impact. Recently psychologic and chrono-biologic factors have psychologic and chrono-biologic factors have been described as potential triggers of lethal been described as potential triggers of lethal arrhythmias. Anniversary of death has been arrhythmias. Anniversary of death has been mentioned as sudden death triggers, but has been mentioned as sudden death triggers, but has been poorly evaluated. poorly evaluated.

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Page 1: SUDDEN DEATH, THE ANNIVERSARY EFFECT Ivan Mendoza, Juan Marques, Federico Moleiro, Ivan Mendoza-B., Francesca Misticchio Experimental Cardiology, Central

SUDDEN DEATH, THE SUDDEN DEATH, THE ANNIVERSARY ANNIVERSARY EFFECTEFFECT

Ivan Mendoza , Juan Marques, Federico Moleiro, Ivan Mendoza , Juan Marques, Federico Moleiro, Ivan Mendoza-B., Francesca Misticchio Ivan Mendoza-B., Francesca Misticchio Experimental Cardiology, Central University of Experimental Cardiology, Central University of Venezuela, Albert Einstein Medical Center, Venezuela, Albert Einstein Medical Center, Philadelphia, USAPhiladelphia, USA

Background:Background: Sudden death (SD) is one of the Sudden death (SD) is one of the major problems of public health and responsible major problems of public health and responsible for nearly half of all cardiac deaths. A better for nearly half of all cardiac deaths. A better understanding of the trigger mechanism will have understanding of the trigger mechanism will have an important preventive impact. Recently an important preventive impact. Recently psychologic and chrono-biologic factors have been psychologic and chrono-biologic factors have been described as potential triggers of lethal described as potential triggers of lethal arrhythmias. Anniversary of death has been arrhythmias. Anniversary of death has been mentioned as sudden death triggers, but has been mentioned as sudden death triggers, but has been poorly evaluated.poorly evaluated.

Page 2: SUDDEN DEATH, THE ANNIVERSARY EFFECT Ivan Mendoza, Juan Marques, Federico Moleiro, Ivan Mendoza-B., Francesca Misticchio Experimental Cardiology, Central

Objective: To evaluate the impact of some family member death anniversary as a trigger of SD in an adult population.

Methods and Results: A consecutive series of 102 documented sudden death cases with ages between 37 and 79 were evaluated. Life circumstances that preceded the final event were investigated. In 69 (68%) the underlying disease was coronary artery disease.

SUDDEN DEATH, THE SUDDEN DEATH, THE ANNIVERSARY EFFECTANNIVERSARY EFFECT

Page 3: SUDDEN DEATH, THE ANNIVERSARY EFFECT Ivan Mendoza, Juan Marques, Federico Moleiro, Ivan Mendoza-B., Francesca Misticchio Experimental Cardiology, Central

Methods and Results: In 13 cases (12,7%) SD occurs on the anniversary date of the traumatic event of death of their parents, 7 (53,8%) the anniversary of father´s death , 5 (38.5%) the anniversary of mother´s death and 1 (7,7%) the anniversary of death of mother and father who died on the same date . In our series no death is related with any other close family member. 10 of 13 (77 %) were male. 4 of 13 (30,8%) had a similar age of the family member who died previously.

SUDDEN DEATH, THE SUDDEN DEATH, THE ANNIVERSARY EFFECTANNIVERSARY EFFECT

Page 4: SUDDEN DEATH, THE ANNIVERSARY EFFECT Ivan Mendoza, Juan Marques, Federico Moleiro, Ivan Mendoza-B., Francesca Misticchio Experimental Cardiology, Central

10%(13)

90%(89)

SD coincident with relative deathanniversary

SD no coincident

SUDDEN DEATH, THE SUDDEN DEATH, THE ANNIVERSARY EFFECTANNIVERSARY EFFECT

Page 5: SUDDEN DEATH, THE ANNIVERSARY EFFECT Ivan Mendoza, Juan Marques, Federico Moleiro, Ivan Mendoza-B., Francesca Misticchio Experimental Cardiology, Central

8%(1)

54%(7)

38%(5)

SD coincident with mother death anniversary

SD coincident with father death anniversary

SD coincident with mother and father anniversarydeath

SUDDEN DEATH, THE SUDDEN DEATH, THE ANNIVERSARY EFFECTANNIVERSARY EFFECT

Page 6: SUDDEN DEATH, THE ANNIVERSARY EFFECT Ivan Mendoza, Juan Marques, Federico Moleiro, Ivan Mendoza-B., Francesca Misticchio Experimental Cardiology, Central

80%(10)

20%(3)

Male Female

SUDDEN DEATH, THE SUDDEN DEATH, THE ANNIVERSARY EFFECTANNIVERSARY EFFECT

Page 7: SUDDEN DEATH, THE ANNIVERSARY EFFECT Ivan Mendoza, Juan Marques, Federico Moleiro, Ivan Mendoza-B., Francesca Misticchio Experimental Cardiology, Central

Discussion: Discussion: ..

Sudden death (SD) is one of the major problems of public health and responsible for nearly half of all cardiac deaths. A better understanding of the trigger mechanism will have an important preventive impact. Sweeney et al report in July 2007 one case of Ventricular tachycardia treated with ICD with anniversary effect.

SUDDEN DEATH, THE SUDDEN DEATH, THE ANNIVERSARY EFFECTANNIVERSARY EFFECT

Page 8: SUDDEN DEATH, THE ANNIVERSARY EFFECT Ivan Mendoza, Juan Marques, Federico Moleiro, Ivan Mendoza-B., Francesca Misticchio Experimental Cardiology, Central

Discussion: Discussion: We emphasized the importance of the We emphasized the importance of the devastating psychological effect as a trigger devastating psychological effect as a trigger of lethal arrhythmias and SD. The of lethal arrhythmias and SD. The anniversary of death of a close family anniversary of death of a close family member, especially mother and/or father is member, especially mother and/or father is an important trigger of SD, predominantly in an important trigger of SD, predominantly in males. Age of SD cases is similar to the males. Age of SD cases is similar to the family member who died previously in one family member who died previously in one third of the casesthird of the cases

SUDDEN DEATH, THE SUDDEN DEATH, THE ANNIVERSARY EFFECTANNIVERSARY EFFECT