stress and the brain 1
TRANSCRIPT
Paul D. MacLean
An interest in the brain requires no justification other than a curiosity to know why we are here, what we are doing here, and where we are going
Chest painsBackachesUrinary frequencyMuscle spasmMemory lossPanic attacksConstipationDiarrheaInsomnia
胸口痛背痛小便頻密肌肉抽搐失憶驚慌病便秘肚瀉失眠
受壓徵兆
頭痛吞嚥問題作嘔胃灼熱胃打結頸痛慢性疲勞頭暈
HeadachesSwallowing problemsNauseaCold sweatsStomach knots NeckachesChronic fatiqueDizziness
受壓徵兆
Ulcerative colitisPeptic ulcerIrritable bowel syndromeHyperventilationAsthmaRheumotoid arthritisAllergiesSkin disorders
潰瘍性結腸炎消化性潰瘍應激性腸綜合徵換氣過度哮喘類風濕性關炎敏感皮膚問題
長期受壓
腎上腺素 (adrenaline, epinephrine)
Fight or flight ( 硬鬥或逃避 )
muscle ( 肌肉 )
metabolism新陳代謝
heart beat心跳
breathing呼吸
muscular fatiquedelay
拖延肌肉疲勞
blood supply tobladder & intestine
decrease減少血液到膀肛
及腸胃 circulation血液巡環
cortisol (hydrocortisone)可的素
carbohydrate metabolism
垂體Pituitary gland
垂體Pituitary gland
男性荷爾蒙
Pineal-Pituitary-Hypothalamus
Melatonin
體溫、口渴、肚餓、飲食、水份、平衡、睡眠、情緒。
主要壓力器官Major stress hormoneorgan
Body temperature, thirst,hunger, eatingwater, balance,sleep, emotion
Pituitary glands
垂體
vasopressin加壓素
TTH促甲狀腺激素
ACTH促腎上腺皮層
激素
ACTH促腎上腺皮層
激素
adrenal cortex腎上腺皮層
adrenaline(ephinephrine)
腎上腺素
fight
flight
fright
noradrenaline(norepinephrine)
Pituitary glands
垂體
noradrenaline(norepinephrine)
adrenaline (ephinephrine)
腎上腺素
Pituitary glands
垂體 去甲腎上腺素
胃、肛門、十二指腸Stomach, Anus,Duodenum
新陳代謝metabolism
急躁Edgy
肌肉鬆Muscle
VitaminsMineralsHormoneAntibodiesProtein
Problems:Glands HormoneImmune SystemBlood PressureUlcer腺收縮荷爾蒙減少免疫系統減弱血壓上升胃酸加增
Pituitary glands
垂體
X
ACTH促腎上腺皮層激素
glucocorticoid : cortisol
(stress hormone)糖皮質激素 : 可的素
腦細胞死亡
過多導致匍萄糖抗氧化
癌症 Cancer心臟病 Heart attack腎病 Kidney problem肝病 Liver problem
Pituitary glands垂體
(Brain cell death)
Glucose drop,antioxidation
• Hans Selye was born in Vienna in 1907. As early as his second year of medical school (1926), he began developing his now-famous theory of the influence of stress on people's ability to cope with and adapt to the pressures of injury and disease
A physician and endocrinologist, Selye also served as a professor and
director of the Institute of Experimental Medicine and Surgery at the
University of Montreal.
• He discovered that patients with a variety of ailments manifested many similar symptoms, which he ultimately attributed to their bodies' efforts to respond to the stresses of being ill. He called this collection of symptoms--this separate stress disease--stress syndrome, or the general adaptation syndrome (GAS).
四通八達
腦幹 :專心 、不專心Reticular Activating System: Attention
http://www.ahs.uwaterloo.ca/~ranney/painanat.html
• William C. Dement (from The Promise of Sleep, 1999, p. 231)
Sleep deprivation is the most common brain impairment
http://www.driesen.com/myelination_-_cns_&_pns.htm
Myelination -- the key to brain enlargingJesse Conel, 30 年研究腦袋
48 Children with ADHD
* more health and learning problem
Omega 6
Omega 3 DHA
STRESSNormal student
Stress &Hostility
Omega 3
Tomohito Hamazaki, Toyama University, Japan
Depression
AustraliaOmega -6 Omega 3
Belgium
Omega 3 EPA
US
EPA
Depression
UK (cell red blood membrane)
3 Omega (DHA)
• Malnutrition and the Brain• Vitamin and mineral deficiencies can be caused
by: • Starvation • Poor diet • Poor absorption of vitamins and minerals • Damage to the digestive system • Infection • Alcoholism
ListeningListening AllergyAllergy Frequent coldsFrequent colds
ƒ™ÓP +∫•̊L©R C Omega 3≥Ω™o§YDHA, EPA
¨àµ£Àç?i¯ÀThiamin, Niacin, Vit B µ¥
四通八達
小腦:動作順暢、動作不順暢Cerebellum: Sensory coordination
The Brain Science General Research Center, RIKEN, and details concerning it were published in the U.S. journal
"Neuron" issued on April 23. The Institute of Physical and Chemical Research (RIKEN)
discovered that CRF (corticotropine discharging hormone) secreted in the brain due to stress is indispensable for motor learning of the cerebellum.
This discovery clarified for the first time in the world that this hormone participates in the motor learning of the cerebellum, and concretely indicated that motor learning is brought about by stress.
CRF is a peptide (protein having only a slight molecular weight) consisting of 41 pieces of amino acid, and it is secreted from hypothalamus, amygdaloid body and other parts of the brain in response to the stress of a loud sound, fear and anxiety.
Very poor fine motor skills
Very poor gross motor skills
Difficulty imitating movementsTrouble with balance, sequences of movements and bilateral coordination
• Sensory Seeking • Hyper-activity • Unawareness of touch or pain, or touching others too often
or too hard (may seem aggressive) • Engaging in unsafe behaviors, such as climbing too high • Enjoying sounds that are too loud, such as TV or radio
volume
Sensory Avoiding • Responding to being touched with aggression
or withdrawal • Afraid of, or becomes sick with movement
and heights • Very cautious and unwilling to take risks
or try new things • Uncomfortable in loud or busy environments
such as sports events, malls • Very picky eater and/or overly sensitive
to food smells
四通八達
小腦:動作順暢、動作不順暢Cerebellum: Sensory coordination
Seven Emotions and Health
Happy
Anger
Worry
Think
Sad
Scared
Fear
Heart
Liver, Gall
Heart, Kidney
Lung, Spleen
Spleen, Heart
Heart, Gall
Kidney, Qi
Addictions self rejection; lack of loveAllergies who are you allergic to?Asthma over-sensitivity, smoother loveBack problem lack of supportColds confusion, small hurtsConstipation refusing to release old ideasCoughs nervousness, annoyance, criticismCramps tension, holding onDeafness What don’t you want to hear?Diabetes deep sorrow; no sweetness in life
Dr Bill Nelson’s “Mental Causation”
Earache Anger; don’t want to hearSinus problem Irritation to one personShoulder problem Burden bearing; over burdenedSkin problem Threatening the person’s securityStuttering Insecurity. Lack of self expressionThroat problem Repressed anger. Emotional hurt swallowed.Tuberculosis Selfishness. Possessiveness.
Dr Bill Nelson’s “Mental Causation”
In the beginning of my work, I matter-of-In the beginning of my work, I matter-of-factly presumed that emotions were in the factly presumed that emotions were in the head or the brain. Now I would say they head or the brain. Now I would say they are really in the body as well. They are are really in the body as well. They are expressed in the body and are part of the expressed in the body and are part of the body. I can no longer make a strong body. I can no longer make a strong distinction between the brain and the bodydistinction between the brain and the body
Candace PertCandace Pert
Matter can neither be created nor Matter can neither be created nor destroyed, and perhaps destroyed, and perhaps biological information flow biological information flow cannot just disappear at death cannot just disappear at death and must be transformed into and must be transformed into another realm. Who can another realm. Who can rationally say "impossible"?rationally say "impossible"?
Candace PertCandace Pert
"The art of medicine consists of keeping the patient amused while nature heals the disease." (Voltaire)
四通八達
大腦:執行運作、執行運作停頓Cortex: Executive
http://www.serv.net/~only1egg/index.html
Integration of Brain FunctioningIncreased Brain Wave Coherence,Neurological Efficiency, and Learning Ability
http://www.tm.org/sidhi/images/integrated-brain.gif
細胞 cells
molecules
atomselectrons
even compared to our nearest relative, the chimpanzee,with whom our deoxyribonucleic acid (DNA) differs by only1 percent, the areas of association cortex are indeed severaltimes greater. It is not surprising that it is these areas ofcortex not directly allocated to controlling movement or toprocessing our senses that are the most intriguing, and at the same time the hardest to understand in terms ofexactly what they do and how they do it.
Susan Greenfield
A large part of association cortex is found at the front of the brain,the prefrontal cortex. …
in growth ; cats 3 percentchimps, 17 percenthuman being 29 percent
四通
受壓細胞變壞的三個階段Under stress: Three stages of cells degeneration
1.警告期 Alarm
2. 適應期 Adapt徵狀消失
Symptomsdisappear
病 sickness癌症 Cancer
有徵狀w/symptoms
3.消耗期Exhaustion
editor of the New England Journal of Medicine, Dr. Franz Ingelfinger, estimated that 85% of all human illnesses are curable by the body’s own healing system.
… the brain is capable of recovery and self-modificationif provided the means.
Richard M Restak
…even though the brain cannot generate new neurons,it does have a remarkable self-generating power.
Richard M Restak
強腦三環3 Rings to
Optimal Brain
腦袋營養 Brain Nutrition
飲食習慣 Eating Habit 營養補給品 Nutritional
Supplement
腦袋減壓 Brain Destress
睡眠習慣 Sleeping Habit
能量改善 Replenish Energy
強化大腦網絡Strengthening the
Neural Network
生活方式 Lifestyle個別跟進 Follow up
My feeling is that there is no scientific reasonto leave spirituality out of medicine. … I havelearned through my own late-twentieth-centuryscience is that the soul, mind, and emotionsdo play an important role in health. What we need is a larger biomedical science to integratewhat was taken out …
Dr Candance Pertat Wellness Conference
If we want to give effective service to our families and our neighbors,as we are commanded to do, we must develop ourselves toour full potential.
We need to enlarge our intellect and perfect our character. We need to become moreChrist-like.
Camilla Kimball
Much unhappiness has been suffered by those people who have never recognized that it is as necessary to make themselves into wholeand harmonious personalities as to keepthemselves clean, healthy, and financiallysolvent.
Wholeness of mind and spirit is not a quality conferred by nature or by God. It is like health and knowledge. We all have the capacity to attain it, but to achieve it depends on our own efforts.
Camillia Kimball
It needs a long, deliberate effort of the mind and theemotions and even the body. …Those who avoid learning or abandon it find that life becomes dry, but when the mind is alert,life is luxuriant.
Camilla Kimball
I love to study; I love to learn. At one time I learned for the sheer pleasure of learning. Now I do it more for the purpose of understanding God’s great creation and my role in it.
Camilla Kimball