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Demolishing the Status Quo in Entrepreneurial Education

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A presentation by Steve Blank

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Page 1: Steve Blank "Entrepreneurial education"

Demolishing the Status Quo in Entrepreneurial Education

Page 2: Steve Blank "Entrepreneurial education"

I Write a Blog

www.steveblank.com

Page 3: Steve Blank "Entrepreneurial education"

This Talk is Based OnBusiness Model GenerationFour Steps to the Epiphany

The Lean Startup

Page 4: Steve Blank "Entrepreneurial education"

This Talk

• What’s a Startup?

• Search versus Execution

• Entrepreneurship As a Mgmt Science

• B-Schools = Large company mgmt

• Incubators = the transition

• E-School = the conclusion

Page 5: Steve Blank "Entrepreneurial education"

First -

What’s A Startup?

Six Types of Startups

Page 6: Steve Blank "Entrepreneurial education"

Startup

Lifestyle Startups Work to Live their Passion

• Serve known customer with

known product

• Pay for their passion

Page 7: Steve Blank "Entrepreneurial education"

Small Business

Startup

Small Business StartupsWork to Feed the Family

• Serve known customer with

known product

• Feed the family

Page 8: Steve Blank "Entrepreneurial education"

Small Business

Startup

Exit Criteria

- Business Model found

- Profitable business

- Existing team

< €100K in revenue

Small Business StartupsWork to Feed the Family

• known customer

known product

• Feed the family

Page 9: Steve Blank "Entrepreneurial education"

Small Business

Startup

- Business Model found

- Profitable business

- Existing team

< $10M in revenue

Small Business Startups

• 5.7 million small businesses in the U.S. <500 employees

• 99.7% of all companies

• ~ 50% of total U.S. workers

http://www.sba.gov/advo/stats/sbfaq.pdf

Page 10: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Scalable Startup

Goal is to solve for:

unknown customer and

unknown features

Search

Page 11: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Exit Criteria

- Business model found

- Total Available Market > €300m

- Can grow to €50/year

Scalable StartupBorn to Be Big

Search Execute

Page 12: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

- Total Available Market > $500m

- Company can grow to $100m/year

- Business model found

- Focused on execution and process

- Typically requires “risk capital”

Scalable Startup

• In contrast a scalable startup is designed to grow big

• Typically needs risk capital

• What Silicon Valley means when they say “Startup”

Search Execute

Page 13: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

Founders depart

- Operating executives

- Professional Mgmt

- Process

- Beginning of scale

The Transition – Founders Leave

BuildSearch Execute

Page 14: Steve Blank "Entrepreneurial education"

ScalableStartup

€3 to 30M Acquisition

Buyable StartupBorn to Be Big

Goal is to solve for:

Internet, Mobile, Gaming Apps

Search Sell

Page 15: Steve Blank "Entrepreneurial education"

ScalableStartup

€3 to e0M Acquisition

Buyable Startup

Goal is to solve for:

Internet and Mobile Apps

Search Sell

Sell to larger company

Page 16: Steve Blank "Entrepreneurial education"

Scalable

Startup

Large

Company

-Business Model found

- i.e. Product/Market fit

- Repeatable sales model

- Managers hired

What’s A Startup?

A Startup is a temporary organization used to search

for a repeatable and scalable business model

Search Execute

Page 17: Steve Blank "Entrepreneurial education"

TransitionLarge

CompanyScalableStartup

Sustaining Innovation

• Existing Market / Known customer

•Known product feature needs

Large Company Sustaining InnovationInnovate or Evaporate

Page 18: Steve Blank "Entrepreneurial education"

Large Company Disruptive Innovation

New Division

TransitionLarge

Company

Disruptive Innovation

•New Market

•New tech, customers, channels

Page 19: Steve Blank "Entrepreneurial education"

Large Company Disruptive Innovation

New Division

TransitionLarge

Company

Disruptive Innovation•Build

•Acquire

- IP

- Talent

- Product

- Customers

- Business

Page 20: Steve Blank "Entrepreneurial education"

Large Non-Profit

Social Startup

Social Entrepreneurship Startups

• Solve pressing social problems

• Social Enterprise: Profitable

• Social Innovation: New Strategies

Page 21: Steve Blank "Entrepreneurial education"

Each of these startups

require different skills

They Can Not Be Taught the Same Way

Page 22: Steve Blank "Entrepreneurial education"

Search Versus Execution

Why Accountants Don’t Run Startups

Page 23: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

Business Model found

- customer needs/product features found

i.e. Product/Market fit

-Found by founders, not employees

- Repeatable sales model

- Managers hired

The Search for the Business Model

Startups Search and Pivot

Page 24: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

-Business Model found

- Product/Market fit

- Repeatable sales model

- Managers hired

- Cash-flow breakeven

- Profitable

- Rapid scale

- New Senior Mgmt

~ 150 people

The Search for the Business Model The Execution of the Business Model

Startups Search, Companies Execute

Page 25: Steve Blank "Entrepreneurial education"

ScalableStartup

LargeCompany

Transition

Traditional Accounting

-Balance Sheet

- Cash Flow Statement

- Income Statement

The Execution of the Business Model

Metrics Versus Accounting

Page 26: Steve Blank "Entrepreneurial education"

ScalableStartup

LargeCompany

Transition

Startup Metrics

- Customer Acquisition Cost

- Viral coefficient

- Customer Lifetime Value

- Average Selling Price/Order Size

- Monthly burn rate

- etc.

Traditional Accounting

- Balance Sheet

- Cash Flow Statement

- Income Statement

The Search for the Business Model The Execution of the Business Model

Metrics Versus Accounting

Page 27: Steve Blank "Entrepreneurial education"

ScalableStartup

LargeCompany

Transition

Sales

-Sales Organization

- Scalable

- Price List/Data Sheets

- Revenue Plan

The Execution of the Business Model

Customer Validation Versus Sales

Page 28: Steve Blank "Entrepreneurial education"

ScalableStartup

LargeCompany

Transition

Customer Validation

- Early Adopters

- Pricing/Feature unstable

- Not yet repeatable

-“One-off’s”

- Done by founders

Sales

- Sales Organization

- Scalable

- Price List/Data Sheets

- Revenue Plan

The Search for the Business Model The Execution of the Business Model

Customer Validation Versus Sales

Page 29: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

Product Management

- Delivers MRD’s

- Feature Spec’s

- Competitive Analysis

- Prod Mgmt driven

The Execution of the Business Model

Customer Development Versus

Product Management

Page 30: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

Customer Development

- Hypothesis Testing

- Minimum Feature Set

- Pivots

- Founder-driven

The Search for the Business Model The Execution of the Business Model

Customer Development Versus

Product Management

Product Management

- Delivers MRD’s

- Feature Spec’s

- Competitive Analysis

Page 31: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

The Execution of the Business Model

Engineering Versus

Agile Development

Engineering

- Requirements Docs.

- Waterfall Development

- QA

- Tech Pubs

Page 32: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

Agile Development

- Continuous Deployment

- Continuous Learning

- Self Organizing Teams

- Minimum Feature Set

- Pivots

The Search for the Business Model The Execution of the Business Model

Engineering Versus

Agile Development

Engineering

- Requirements Docs.

- Waterfall Development

- QA

- Tech Pubs

Page 33: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

Business Plan

-Plan describes “knowns”

- Known features for line extensions

- Known customers/markets

- Known business model

The Execution of the Business Model

Startups Model, Companies Plan

Page 34: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

Business Model

- Unknown customer needs

- Unknown feature set

- Unknown business model

- Model found by iteration

The Search for the Business Model

Startups Model, Companies Plan

The Execution of the Business Model

-Plan describes “knowns”

- Known features for line extensions

- Known customers/markets

- Known business model

Page 35: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

Startups Are Not Small Versions of

Large Companies

BuildSearch Execute

Yet our curriculums assume they are –

we teach that the knowledge is interchangeable

Page 36: Steve Blank "Entrepreneurial education"

Entrepreneurship as a

Management Science

E-School instead of B-School

Page 37: Steve Blank "Entrepreneurial education"

Business as a Management Science

• 1601 East India Company

• 300 years of companies

without MBA credentials

•1908 Harvard first MBA

Page 38: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

-Execution

- Strategy

- Accounting

- Products

- Engineering

- Management

-Administration

Business School

Business School Topics

Page 39: Steve Blank "Entrepreneurial education"

Large Company

Business School

Business School Courses

Courses

-Managerial Finance/Accounting

- Managing Groups and Teams

- Financial Accounting

- Operations

- Modeling for Optimization

- Global Value Chain Strategies

ScalableStartup

Transition

Page 40: Steve Blank "Entrepreneurial education"

B-School Results?

• U.S. corporations went from local to national

then international

•Cadre of experienced managers to match

• Experts on finance and growth (Dupont/GM)

B-Schools made the 20th Century

the American business century

Page 41: Steve Blank "Entrepreneurial education"

Business School Focus on

Large Company Strategies

Execution versus Search

Page 42: Steve Blank "Entrepreneurial education"

Business School Limitations

•Most Professors consult for large corporations

• Most believe startups are just smaller versions of

large companies

• Most B-school entrepreneurship programs are

side-shows

Page 43: Steve Blank "Entrepreneurial education"

Irony:

21st Century Job Growth will Come

from New Ventures

Page 44: Steve Blank "Entrepreneurial education"

Incubators a Reaction to the lack of Practical

University Entrepreneurship

• 1959 Josephy Mancuso - Batavia Industrial Ctr.

• 1996 IdeaLab

•2005 Y-Combinator

•2011 100+ Incubators world-wide

Page 45: Steve Blank "Entrepreneurial education"

Startup Incubators

•Hands-on (experience vs. theory)

• Goal: create a company and jobs

• Full-time residential, stipend-based program

• Curriculum: product development + best practices

Page 46: Steve Blank "Entrepreneurial education"

What’s Missing?

A Repeatable Methodology

Not Just War Stories

Page 47: Steve Blank "Entrepreneurial education"

Startups Are Not Smaller Versions

of Large Companies

Large Companies Execute Known Business Models

Page 48: Steve Blank "Entrepreneurial education"

Startups Are Not Smaller Versions

of Large Companies

Startups Search for Unknown Business Models

Page 49: Steve Blank "Entrepreneurial education"

E-School

•Complete curriculum with Hands-on emphasis

• Goal: methodology for startup creation

• Can be taught anywhere

- University

- Incubator

- Remotely

• Curriculum: about the search for a business model

Page 50: Steve Blank "Entrepreneurial education"

The Business Model:

Any company can be described in 9 building blocks

Page 51: Steve Blank "Entrepreneurial education"

CUSTOMER SEGMENTS

which customers and users are you serving?

which jobs do they really want to get done?

Page 52: Steve Blank "Entrepreneurial education"

VALUE PROPOSITIONS

what are you offering them? what is that

getting done for them? do they care?

Page 53: Steve Blank "Entrepreneurial education"

CHANNELS

how does each customer segment want to be

reached? through which interaction points?

Page 54: Steve Blank "Entrepreneurial education"

CUSTOMER RELATIONSHIPS

what relationships are you establishing with each

segment? personal? automated? acquisitive? retentive?

Page 55: Steve Blank "Entrepreneurial education"

REVENUE STREAMS

what are customers really willing to pay for? how?

are you generating transactional or recurring revenues?

Page 56: Steve Blank "Entrepreneurial education"

KEY RESOURCES

which resources underpin your business model?

which assets are essential?

Page 57: Steve Blank "Entrepreneurial education"

57

KEY ACTIVITIES

which activities do you need to perform well in

your business model? what is crucial?

Page 58: Steve Blank "Entrepreneurial education"

KEY PARTNERS

which partners and suppliers leverage your model?

who do you need to rely on?

Page 59: Steve Blank "Entrepreneurial education"

COST STRUCTURE

what is the resulting cost structure?

which key elements drive your costs?

Page 60: Steve Blank "Entrepreneurial education"

60images by JAM

customer

segments

key

partners

cost

structure

revenue

streams

channels

customer

relationships

key

activities

key

resources

value

proposition

Page 61: Steve Blank "Entrepreneurial education"

sketch out your business model

Page 62: Steve Blank "Entrepreneurial education"

sketch out your business models

Page 63: Steve Blank "Entrepreneurial education"

But,

Realize They’re Hypotheses

Page 64: Steve Blank "Entrepreneurial education"

9 Guesses

Guess Guess

Guess

Guess

Guess

Guess

Guess

GuessGuess

Page 65: Steve Blank "Entrepreneurial education"

Customer Development

Get Out of the Building

The founders

^

Page 66: Steve Blank "Entrepreneurial education"

Customer DevelopmentThe Search For the Business Model

CompanyBuilding

CustomerDiscovery

CustomerValidation

Customer Creation

Pivot

Page 67: Steve Blank "Entrepreneurial education"

• Stop selling, start listening

• Test your hypotheses

• Continuous Discovery

• Done by founders

Customer Discovery

CustomerDiscovery

CustomerValidation

CompanyBuilding

CustomerCreation

Page 68: Steve Blank "Entrepreneurial education"

Test Hypotheses:

•Product

• Market Type

• Competition

Turning Hypotheses to Facts

Page 69: Steve Blank "Entrepreneurial education"

Test

Hypotheses:

•Problem

• Customer

• User

• Payer

Page 70: Steve Blank "Entrepreneurial education"

Test Hypotheses:

•Channel

Page 71: Steve Blank "Entrepreneurial education"

Test

Hypothese

s:

•Problem

Customer

• User

• Payer

Test

Hypotheses

:

•Demand

Creation

Test

Hypotheses:

•Channel

Test

Hypotheses:

•Product

• Market

Type

Competitive

Test Hypotheses:

•Pricing Model /

Pricing

Test Hypotheses:

•Size of

Opportunity/Market

• Validate Business Model

Test

Hypothese

s:

•Channel

(Customer

)

(Problem)

Page 72: Steve Blank "Entrepreneurial education"

Test

Hypothese

s:

•Problem

Customer

• User

• Payer

Test

Hypotheses

:

•Demand

Creation

Test

Hypotheses:

•Channel

Test

Hypotheses:

•Product

• Market

Type

Competitive

Test Hypotheses:

•Pricing Model /

Pricing

Test Hypotheses:

•Size of

Opportunity/Market

• Validate Business Model

Test

Hypothese

s:

•Channel

(Customer

)

(Problem)

Customer

Developme

nt Team

Agile

Developme

nt

Page 73: Steve Blank "Entrepreneurial education"

The Minimum Viable Product (MVP)

• Smallest feature set that gets you the most …

- orders, learning, feedback, failure…

Page 74: Steve Blank "Entrepreneurial education"

The Pivot

•The heart of Customer Development

•Iteration without crisis

•Fast, agile and opportunistic

Page 75: Steve Blank "Entrepreneurial education"

Pivot Cycle Time Matters

•Speed of cycle minimizes cash needs

•Minimum feature set speeds up cycle time

• Near instantaneous customer feedback

drives feature set

Page 76: Steve Blank "Entrepreneurial education"

The Pivot

A Pivot is the change of one or more

Business Model Canvas Components

Page 77: Steve Blank "Entrepreneurial education"

The Pivot

A Pivot is the change of one or more

Business Model Canvas Components OB/GYNs

PCPs

Direct Sales to

hospitals

Distributor

Strong clinical

data

Training

Maintenance

Conferences

CME courses

Product Development

Clinical trials

Operating Costs

Marketing Costs

Capital Equipment Sales

and disposable item

Per use fees

Product

Development

IP

Clinical trials

FDA

Publishing

IP

Leading doctors

Technical

Expertise

Leading doctors

Key Opinion

Leaders

3rd party

manufacturers

Distributors

Breast Cancer

Foundations

ACOG

ACS

Doctors:

Earlier

detection

Price

Accuracy

Patients:

Radiation Free

Non-Invasive

Page 78: Steve Blank "Entrepreneurial education"

How Does This Really Work?

Stanford Lean LaunchPad Class

Page 79: Steve Blank "Entrepreneurial education"

How Does This Really Work?

Stanford Lean LaunchPad Class

8 Weeks From an Idea to a Business

Page 80: Steve Blank "Entrepreneurial education"

Pivot Example

Robotic Weeding

Talked 75 Customers in 8 Weeks

Page 81: Steve Blank "Entrepreneurial education"

Our initial plan

Confidential

Page 82: Steve Blank "Entrepreneurial education"

20 interviews, 6 site visits…

We got OUR Boots dirtyWeeding

Visited two farms in Salinas Valley to better understand problem

Interviewed:• Bolthouse Farms, Large Agri-Industry in Bakersfield

• White Farms, Large Peanut farmer in Georgia• REFCO Farms, large grower in Salinas Valley• Rincon Farms, large grower in Salinas Valley• Small Organic Corn/Soy grower in Nebraska

• Heirloom Organics, small owner/operator, Santa Cruz Mts• Two small organic farmers at farmers market

• Ag Services of Salinas, Fertilizer applicator

MowingInterviewed:

• Golf: Stanford Golf course • Parks: Stanford Grounds Supervisor, head of maintenance and

lead operator (has crew of 6)• Toro dealer (large mower manufacturer)

• User of back-yard mowing system• Maintenance Services for City of Los Altos

• Colony Landscaping (Mowing service for stadiums)

Page 83: Steve Blank "Entrepreneurial education"

Business Plan Autonomous Vehicles for Mowing & Weeding

We reduce

operating cost

- Labor reduction

- Better

utilization of

assets (eg mow or

weed at nights)

- Improved

performance (less

rework, food

safety)

Mowing

- Owners of

public or

commercially

used green

spaces (e.g. golf

courses)

- Landscaping

service provider

Weeding

- Farmers with

manual weeding

operations

Dealers sell,

installs and

supports customer

Co. trains dealers,

supports dealers

- Mowing

Dealers

- Ag Dealers

- Innovation

- Customer

Education

- Dealer training

Dealer discount

COGS seek a 50-60% Gross Margin

Heavy R&D investment

- Dealers

(Mowing and

Ag)

- Vehicle OEMs

(John Deere,

Toro, Jacobsen,

etc)

- Research labs

Asset sale

Our revenue stream derives from selling the

equipment

Engineers on

Autonomous

vehicles, GPS,

path-planning

Page 84: Steve Blank "Entrepreneurial education"

Found weeding in organic crops is HUGE

problem; 50 - 75% of costs

Crews of 100s-1000

Back-breaking task

(Ilegal) labor harder to get

1-5 weedings per year/field

$250-3,500 per acre and increasing

Food contamination risk

Page 85: Steve Blank "Entrepreneurial education"

Decision to make – mowing vs weeding

Application If ROI is < 1 yr they will

buy

Labor costs significant?

Autonomouswould solve

problem?

TAM

Mowing of large fields

Yes.Professionally

run organizations

Yes Yes Adjusted up toxxx

Weeding in Agriculture

Agri Industry: YES!

Large Growers: Yes

Small Growers: No

YES! for organic crops

They are spending $500/ac!

Not necessarily

Key need is weed vs. crop differentiation

TAM increasedto $2.6 B (Total

organic)

Target Market (organic

specialty) 162 M/yr

18%/yr growth

Page 86: Steve Blank "Entrepreneurial education"

Autonomous vehiclesWEEDING

We reduce

operating cost

- Labor reduction

(100 to 1)

- Reduced risk of

contamination

- Mitigate labor

availability

concerns

- Low density

vegetable

growers

- High density

vegetable

growers

- Thinning

operations

- Conventional

vegetables

Dealers sell,

installs and

supports customer

Co. trains dealers,

supports dealers

- Ag Dealers

- Ag Service

providers

- Innovation

- Customer

Education

- Dealer training

Dealer discount

COGS seek a 50-60% Gross Margin

Heavy R&D investment

- Ag Dealers

- Ag Service

providers

- Research labs

Asset sale

Our revenue stream derives from selling the

equipment

Engineers on

Machine Vision

Two problems:

- Identification

- Elimination

Page 87: Steve Blank "Entrepreneurial education"

1 Week – 1 CarrotBot

Confidential

Page 88: Steve Blank "Entrepreneurial education"

CARROTBOT

Machine Vision data collection platform

Monochrome & Color Cameras

Laser-line sweep (depth measurement)

Encoders (position/velocity)

Onboard data acquisition & power

CarrotBot 1.0

Page 89: Steve Blank "Entrepreneurial education"

The Business Plan Canvas Updated

•Research Labs

•Equipment

Manufacturers

•Distribution

Network

•Service

Providers

•Technology

Design

•Marketing

•Demo and

customer

feedback•Cost

Reduction

•Remove labor

force pains

•Eliminate bio-

waste hazards•IP – Patents

•Video

Classifier Files

•Robust

Technology

•Farming

conventions.

•Demo, demo,

and demo!!

•Proximity is

paramount

•Organic

Farmers

•Weeding

Service

Providers

•Conventional

Farmers•Dealers

•Direct Service

•Indirect Service

• … then Dealers

•Asset Sale

•Direct Service with

equipment rental

•… then Asset Sale

Value-Driven

Page 90: Steve Blank "Entrepreneurial education"

Visit Highlights

Above: Organic Carrots, 7wks.

Top right: Conventional carrots

Bottom Right: Very weedy. Will require

multiple passes of hand weeding

Page 91: Steve Blank "Entrepreneurial education"

Visit Highlights

Carrot vs. Weeds

Due to small root systems, carrots have no chance against weeds

Page 92: Steve Blank "Entrepreneurial education"

Visit Highlights

Organic Broccoli, closely

cultivated. Weeds close

to plants are hand-

picked

Page 93: Steve Blank "Entrepreneurial education"

Visit Highlights

State of the Art in Weeding Technology

for Organic Crops

Page 94: Steve Blank "Entrepreneurial education"

Customer Hypothesis

Us Dealer

Large Growers

Industrial Growers

Us Dealer

Industrial Growers

Large Growers

Service Providers

Equipment Rental

Hypothesis Confirmed

• Growers interested in own equipment

• Industrial (10,000s of acres)

• Large (1,000s of acres)

• Willing to pay $100k for one

unit

• Smaller growers (100s of acres)

usually subcontract the labor services

or rent equipment

• All purchases through local dealers

•Customer service is essential

Pre-Test

Post-Test

Page 95: Steve Blank "Entrepreneurial education"

Customer Map #1 – Industrial Growers

End User

Influencer

Recommender

Decision Maker

Approver

Example: Bolthouse Farms – Large Industrial Carrot

Producer – 8K acres/yr• Equipment

Operator

• Director, Ag

Technology• Justin Grove,

interviewed

• VP, Growing

Operations

• CFO, CEO (Jeff

Dunn)

• Local Farm Mgr• Cliff Kirkpatrick,

visited

Equipment

Operator

Cliff, Farm Mgr

Page 96: Steve Blank "Entrepreneurial education"

Customer Map #2 – Service Providers

End User

Influencer

Recommender

Decision Maker & Approver

Example: Ag Services – Service Provider, Salinas

Valley• Equipment

Operator

• Service Mgr

• ?? (service mgr’s

boss)

Me (left), Marty (middle, Service

Mgr), Doug (right, Grower)

• Grower

Page 97: Steve Blank "Entrepreneurial education"

The Business Plan Canvas Updated

•Research Labs

•Equipment

Manufacturers

•Distribution

Network

•Service

Providers

•Technology

Design

•Marketing

•Demo and

customer

feedback•Cost

Reduction

•Remove labor

force pains

•Eliminate bio-

waste hazards•IP – Patents

•Video

Classifier Files

•Robust

Technology

•Farming

conventions.

•Demo, demo,

and demo!!

•Proximity is

paramount

•Mid/Large

Organic Farmers

•Agricultural

corporations

•Weeding Service

Providers

•Mid/Large

Conventional

Farmers•Direct Service

•Indirect Service

• … then Dealers

•Direct Service with

equipment rental

•($1,500/d; 120d/yr )

•Low density: $1,500/d

•High density: $6,000/d

Value-Driven

Page 98: Steve Blank "Entrepreneurial education"

World Ag Expo interviews:

the need is real and wide spread

• 10+ interviews at show

– Everyone confirmed the need

– Robocrop, UK based, crude competitor sells for $171 K

• Revenue Stream

– Mid to small growers prefer a service

– Large growers prefer to buy, but OK with service until technology is proven

– Charging for labor cost saved is OK, as we provide other benefits (food safety, labor availability)

Confidential

Page 99: Steve Blank "Entrepreneurial education"

The Business Plan Canvas Updated

•Research Labs

•Equipment

Manufacturer

•Distribution

Network

•Service

Providers

•2 or 3 Key

Farms

•Technology

Design

•Marketing

•Demo and

customer

feedback•Cost

Reduction

•Remove labor

force pains

•Eliminate bio-

waste hazards•IP – Patents

•Video

Classifier Files

•Robust

Technology

•Farming

conventions.

•Demo, demo,

and demo!!

•Proximity is

paramount

•Mid/Large

Organic Farmers

•Agricultural

corporations

•Weeding Service

Providers

•Mid/Large

Conventional

Farmers•Direct Service

•Indirect Service

• … then Dealers

•Direct Service with

equipment rental

•Low density: $1,500/d

•High density: $6,000/d

Value-Driven

• R&D

• Bill of Materials

• Training & Service

• Sales

Page 100: Steve Blank "Entrepreneurial education"

Autonomous weeding - Final

We reduce

operating cost

- Labor reduction

(100 to 1)

- Reduced risk of

contamination

- Mitigate labor

availability

concerns

- Low density

vegetable

growers

- High density

vegetable

growers

- Thinning

operations

- Conventional

vegetables

Direct

- Provide high

quality service at

competitive price

Direct

- Alliance with

service providers

- Eventually sell

through dealers

- Innovation

- Customer

Education

- Dealer training

Costs for service provision

COGS seek a 50-60% Gross Margin

Heavy R&D investment

- Ag Service

providers

- Research

Institutes (eg UC

Davis, Laser

Zentrum

Hannover)

- 3-4 key farms

Service provision

- Charge by the acre with modifier according to

weed density

- Eventually move to asset sale

Engineers on

Machine Vision

Two problems:

- Identification

- Elimination

Page 101: Steve Blank "Entrepreneurial education"

MammOpticsFinal project presentation for E 245 Winter 2011

Page 102: Steve Blank "Entrepreneurial education"

MammOptics

Initial Idea

Breast cancer

Leading cause of cancer in women

190,000 diagnosis every year US

41,000 deaths every year US

Increasing diagnosis rates

Mammography

15%-25% false negatives rate

25% false positives rate

Requires X-ray radiation

Low resolution

Novel technology based on

RF-modulated optical

spectroscopy

MammOptics

- Earlier

detection

- Non-

radiative

- Non-

Page 103: Steve Blank "Entrepreneurial education"

MammOptics

Technology Comparison

RiskInvasivenes

sResolution

False

Pos.

False

Neg.

Device

Cost

Time

Required

MammOptics

Mammography High High .6 cm 25% 30% 20-50k 20 min.

MRI Medium Medium .1 cm 70% 5% 1000k 45 min.

Ultra-Sound Very Low Very Low >.6 cm >30% >40% 5-15k 20 min.

I.I.T.Y.I.W.H.T.K.Y

Page 104: Steve Blank "Entrepreneurial education"

MammOptics

Business Model Canvas 1 of 4

Radiation-free

Earlier detection

Non-invasive

Pioneering

radiologists in

hospitals

Direct sales to

hospitals

Strong clinical

data

Training

Maintenance

Product Development

Clinical trials

Operating CostsCapital equipment sales

and disposable item

Product

Development

IP

Clinical trials

FDA

IP

Leading doctors

Technical

Expertise

Hospitals

Leading doctors

3rd party

manufacturers

Distributors

Page 105: Steve Blank "Entrepreneurial education"

MammOptics

Business Model Canvas 1 of 4

Radiation-free

Earlier detection

Non-invasive

Pioneering

radiologists in

hospitals

Direct sales to

hospitals

Strong clinical

data

Training

Maintenance

Product Development

Clinical trials

Operating CostsCapital equipment sales

and disposable item

Product

Development

IP

Clinical trials

FDA

IP

Leading doctors

Technical

Expertise

Hospitals

Leading doctors

3rd party

manufacturers

Distributors

MammOptics

Business Model Canvas 1 of 4

Page 106: Steve Blank "Entrepreneurial education"

Finding the right customerFrom radiologists to gynecologists

Page 107: Steve Blank "Entrepreneurial education"

MammOptics

Excursions into hospitals

Leading

doctors

Patients

Hospital

Managers

Technicians

Debra Ikeda

Jason Davies

Jafi Alissa Lipson

Sunita Pal

6 women >40

8 women <40

Alicia X-ray

mammography

Paul Billings

Holly V. Gautier

Page 108: Steve Blank "Entrepreneurial education"

MammOptics

Hospital purchasing decision tree

Page 109: Steve Blank "Entrepreneurial education"

MammOptics

Hospital purchasing decision tree

Page 110: Steve Blank "Entrepreneurial education"

MammOptics

Private practice purchasing decision tree

Page 111: Steve Blank "Entrepreneurial education"

MammOptics

Private practice purchasing decision tree

Page 112: Steve Blank "Entrepreneurial education"

Pioneering

Doctors

Hospitals

OB/GYNs

PCPs

Direct Sales to

doctors

Strong clinical

data

Training

Maintenance

Product Development

Clinical trials

Operating Costs

Capital Equipment Sales

and disposable item

Product

Development

IP

Clinical trials

FDA

IP

Leading doctors

Technical

Expertise

Hospitals (Capital

Spending

Committee)

Leading doctors

3rd party

manufacturers

Distributors

Research

Hospitals

Doctors:

Earlier

detection

Price

Accuracy

Patients:

Radiation Free

Non-Invasive

MammOptics

Business Model Canvas 2 of 4

Page 113: Steve Blank "Entrepreneurial education"

Pioneering

Doctors

Hospitals

OB/GYNs

PCPs

Direct Sales to

doctors

Strong clinical

data

Training

Maintenance

Product Development

Clinical trials

Operating Costs

Capital Equipment Sales

and disposable item

Product

Development

IP

Clinical trials

FDA

IP

Leading doctors

Technical

Expertise

Hospitals (Capital

Spending

Committee)

Leading doctors

3rd party

manufacturers

Distributors

Research

Hospitals

Doctors:

Earlier

detection

Price

Accuracy

Patients:

Radiation Free

Non-Invasive

MammOptics

Business Model Canvas 2 of 4

Page 114: Steve Blank "Entrepreneurial education"

Getting to our customerThe world of direct sales and medical marketing

Page 115: Steve Blank "Entrepreneurial education"

MammOptics

Interviews

Breast Cancer

Advocacy Groups

OB/GYNs

FDA/Clinical

Trials

Medical Sales

Be Bright Pink

Jennifer Glover

Dr. Cindy Woo

Dr. Jags Powers

Dr. Aaron

Shuvkan

Katrina Bell

Tanay Dudhela

Jed Hwang

Phyllis Whitely

Carl Simpson

Page 116: Steve Blank "Entrepreneurial education"

Market Adoption

Key Opinion Leaders (KOLs)

Medical Journals

Continuing Medical Education

Conferences

Breast Cancer Advocacy Groups

American College of Obstetricians

and Gynecologists (ACOG)

MammOptics

Marketing

Page 117: Steve Blank "Entrepreneurial education"

Market Adoption

Key Opinion Leaders (KOLs)

Medical Journals

Continuing Medical Education

Conferences

American College of Obstetricians

and Gynecologists (ACOG)

American College of Obstetricians

and Gynecologists (ACOG)

Access to ACOG by

former member

Strong influence on doctors via ACOG Standard of Care Strongly

influenced by KOLs

MammOptics

Marketing

Page 118: Steve Blank "Entrepreneurial education"

Market Adoption

Key Opinion Leaders (KOLs)

Medical Journals

Continuing Medical Education

Conferences

American College of Obstetricians

and Gynecologists (ACOG)

American College of Obstetricians

and Gynecologists (ACOG)

Researchers conducting important

clinical trialsResearchers

with numerous

publications

Outsourced survey

research

Researchers with strong

peer recommendati

ons

MammOptics

Marketing

Page 119: Steve Blank "Entrepreneurial education"

Market Adoption

Key Opinion Leaders (KOLs)

Medical Journals

Continuing Medical Education

Conferences

American College of Obstetricians

and Gynecologists (ACOG)

American College of Obstetricians

and Gynecologists (ACOG)

Focus on prominent journals

Need two big publications

Choose KOL as Principal

Investigators (PI)

MammOptics

Marketing

Page 120: Steve Blank "Entrepreneurial education"

Market Adoption

Key Opinion Leaders (KOLs)

Medical Journals

Continuing Medical Education

Conferences

American College of Obstetricians

and Gynecologists (ACOG)

American College of Obstetricians

and Gynecologists (ACOG)

Effective method for educating doctors

Doctors required to

attend workshops

Workshop must be approved by

ACOG

Taught by objective medical experts

MammOptics

Marketing

Page 121: Steve Blank "Entrepreneurial education"

Market Adoption

Key Opinion Leaders (KOLs)

Medical Journals

Continuing Medical Education

Conferences

American College of Obstetricians

and Gynecologists (ACOG)

American College of Obstetricians

and Gynecologists (ACOG)

ACOG Annual Clinical Meeting

Miami Breast Cancer

Conference

Opportunity for feedback from doctors

MammOptics

Marketing

Page 122: Steve Blank "Entrepreneurial education"

Market Adoption

Key Opinion Leaders (KOLs)

Medical Journals

Continuing Medical Education

Conferences

Breast Cancer Advocacy Groups

American College of Obstetricians

and Gynecologists (ACOG)

Trusted information source for patients

Critical opinion leader for

technology adoption

Access to media outlets

MammOptics

Marketing

Page 123: Steve Blank "Entrepreneurial education"

Individual

Doctors

Purchasing

Administrators

High value

medical products(e.g. cardiovascular

stents)

Commodity

medical products(e.g. latex gloves)

• Doctor education

• Direct feedback from

doctors

• Very expensive

• No doctor

education

• No customer

feedback

• Inexpensive

Direct Sales

Distributors

MammOptics

Channel Strategies and Costs

Individual Doctors

Purchasing Administrators

Page 124: Steve Blank "Entrepreneurial education"

Channel Strategies and CostsMammOptics

5 dedicated sales people

$150,000 each/year

Hire nurses or technicians

with established

relationships

Early adopter feedback

Continue with core

group of sales

people

Use women’s

healthcare

equipment

distributor

Already established

network of

customers

Sales strategy 1 Sales strategy 2

Page 125: Steve Blank "Entrepreneurial education"

MammOptics

Pricing Strategy

Equipment Lease model Per-use

model

Consumable

Cost of the

device

Service per

year

Per-use fee

Consumable

$50,000

$3,000

0

0

$5,000

$10,000

0

0

$5,000

0

$50

0

$25,000

0

0

$20

Page 126: Steve Blank "Entrepreneurial education"

MammOptics

Pricing Strategy

Equipment Lease model Per-use

model

Consumable

Cost of the

device

Service per

year

Per-use fee

Consumable

$50,000

$3,000

0

0

$5,000

$10,000

0

0

$5,000

0

$50

0

$25,000

0

0

$20

Page 127: Steve Blank "Entrepreneurial education"

ACOG

ACS

Doctor

specialty

committee

Hospital

Administration

Technician

RadiologistMammography

MammOptics

Customer Workflow

Current market Insurance

Page 128: Steve Blank "Entrepreneurial education"

ACOG

ACS

Doctor

specialty

committee

Hospital

Administration

Technician

RadiologistMammography

MammOptics

Customer Workflow

Current market

But what would

happen if we

replace

mammography?

Insurance

Page 129: Steve Blank "Entrepreneurial education"

ACOG

ACS

Doctor

specialty

committee

Hospital

Administration

Technician

Radiologis

tMammography

MammOptics

Customer Workflow

Breast

RadiologistsTechnicians Hospitals

Loss of jobs

Loss of jobs Eliminates loss leader

Puts emphasis on

biopsies

Insurance

Page 130: Steve Blank "Entrepreneurial education"

ACOG

ACS

Doctor

specialty

committee

Hospital

Administration

Technician

RadiologistMammography

MammOptics

Customer Workflow

Insurance

Page 131: Steve Blank "Entrepreneurial education"

ACOG

ACS

Doctor

specialty

committee

Hospital

Administration

Technician

Radiologis

tMammography

MammOptics

Customer Workflow

Insurance

Same cost as mammography

($140)

Reduced number of biopsies

($1000)

ACOG/ACS

Improved healthcare

(mammography weak technique)

Insurance

Page 132: Steve Blank "Entrepreneurial education"

ACOG

ACS

Doctor

specialty

committee

Hospital

Administration

Technician

Insurance

RadiologistMammography

MammOptics

Customer Workflow

Page 133: Steve Blank "Entrepreneurial education"

Insurance

Doctor

specialty

committee

Hospital

Administration

Technician

RadiologistMammography

MammOptics

Customer Workflow

ACOG

ACS

MammOptics

Patient PCP

OB/GY

N

Page 134: Steve Blank "Entrepreneurial education"

Insurance

Doctor

specialty

committee

Hospital

Administration

Technician

Radiologis

tMammography

MammOptics

Customer Workflow

ACOG

ACS

MammOptic

s

Patient PCP

OB/GY

N

Hospital

Administration

Technician

Radiologis

tMammography

MammOptic

s

Patient PCP

OB/GY

N

PCP OB/GYNs

Increased revenue

More complete patient care

Patient

Improved healthcare

Comfort

MammOptics

Revenue

Page 135: Steve Blank "Entrepreneurial education"

ACOG

ACS

Doctor

specialty

committee

Hospital

Administration

Technician

Insurance

RadiologistMammography

MammOptics

Customer Workflow

MammOptics

Patient PCP

OB/GY

N

Page 136: Steve Blank "Entrepreneurial education"

OB/GYNs

PCPs

Direct Sales to

hospitals

Distributor

Strong clinical

data

Training

Maintenance

Conferences

CME courses

Product Development

Clinical trials

Operating Costs

Marketing Costs

Capital Equipment Sales

and disposable item

Per use fees

Product

Development

IP

Clinical trials

FDA

Publishing

IP

Leading doctors

Technical

Expertise

Leading doctors

Key Opinion

Leaders

3rd party

manufacturers

Distributors

Breast Cancer

Foundations

ACOG

ACS

Doctors:

Earlier

detection

Price

Accuracy

Patients:

Radiation Free

Non-Invasive

MammOptics

Business Model Canvas 3 of 4

Page 137: Steve Blank "Entrepreneurial education"

OB/GYNs

PCPs

Direct Sales to

hospitals

Distributor

Strong clinical

data

Training

Maintenance

Conferences

CME courses

Product Development

Clinical trials

Operating Costs

Marketing Costs

Capital Equipment Sales

and disposable item

Per use fees

Product

Development

IP

Clinical trials

FDA

Reimburseme

ntPublishing

IP

Leading doctors

Technical

Expertise

Leading doctors

Key Opinion

Leaders

3rd party

manufacturers

Distributors

Breast Cancer

Foundations

ACOG

ACS

Doctors:

Earlier

detection

Price

Accuracy

Patients:

Radiation Free

Non-Invasive

MammOptics

Business Model Canvas 3 of 4

Page 138: Steve Blank "Entrepreneurial education"

Building the companyThe backstage of a medical device company

Page 139: Steve Blank "Entrepreneurial education"

MammOptics

Interviews

FDA Clinical Trials

Manufacturing

Venture

Capitalists

Reimbursement

Stanford

StatisticsSteve

Axelrod

Marga Ortigas-

Wedekind

Nick Mourlas

Don

Archambault

Shannon Bergstedt

Ali Habib

Dana Mead

Bill Starling

Doctors/Sales Dr. Aron

Shuftan

Jed Hwang

Michael J. Nohr

Page 140: Steve Blank "Entrepreneurial education"

Manufacturing

MammOptics

Partners

Choose

manufacturing

facility close to

home

Page 141: Steve Blank "Entrepreneurial education"

Manufacturing Reimbursement

MammOptics

Partners

Difficult to get

coverage for

new product.

Manufacturing

MammOptics

Partners

Page 142: Steve Blank "Entrepreneurial education"

Reimbursement PartnersMammOptics

Insurances

CPT Codes

$75-$150

Page 143: Steve Blank "Entrepreneurial education"

MammOptics

Partners

Manufacturing

FDA Clinical

Trials

Reimbursement

510K vs. PMA

Largest cost

Biggest

financial risk

Page 144: Steve Blank "Entrepreneurial education"

Clinical Trials

12/4/2009

Stage 1Pilot trials

50 patients

$600K

MammOptics

6 months

Feasibility

Comparison

with

mammograph

y

Page 145: Steve Blank "Entrepreneurial education"

Clinical Trials

12/4/2009

MammOptics

6 months 15 months

Stage 1Pilot trials

Stage 2Interim trials

500 patients

$7.2M

Prove superior

safety-efficacy

& sensitivity

Page 146: Steve Blank "Entrepreneurial education"

Clinical Trials

12/4/2009

MammOptics

6 months 15 months

Stage 1Pilot trials

Stage 2Interim trials

24 months

Stage 3FDA pivotal

trials

1500 patients

$20.5M

FDA class II,

510(K) w/ trials

Focus on

superiority &

economic end-

points

Page 147: Steve Blank "Entrepreneurial education"

Clinical Trials

12/4/2009

MammOptics

6 months 15 months

Stage 1Pilot trials

Stage 2Interim trials

Stage 3FDA pivotal

trials

Stage 4Post-market

studies2000 patients

$26.8M

Specific Cat III

CPT/ACP Codes

Market traction

24 months24 months

Page 148: Steve Blank "Entrepreneurial education"

Clinical Trials

12/4/2009

MammOptics

6 months 15 months

Stage 1Pilot trials

Stage 2Interim trials

Stage 3FDA pivotal

trials$600K

$7.2M

$20.5M

$26.8M

Stage 4Post-market

studies

24 months 24 months

Page 149: Steve Blank "Entrepreneurial education"

Clinical Trials

12/4/2009

MammOptics

Page 150: Steve Blank "Entrepreneurial education"

MammOptics

PartnersMammOptics

Partners

Manufacturing

FDA Clinical

Trials

Reimbursement

Financial

timeline

Funding

Page 151: Steve Blank "Entrepreneurial education"

$10M

$15M

2012

Series A

$3.5 MM

Ca

sh

Re

se

rve

Clin

ica

l M

ile

sto

ne

s

$5M

Initialize

De

sig

n

Mile

sto

ne

sR

eg

ula

tory

/ IP

M

ile

sto

ne

s

Q1 Q2 Q3 Q4

2013

Q1 Q2 Q3 Q4

2014

Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4

2015 2016

Series B

$9 MM

System

2017

Q1 Q2Q1 Q2 Q3 Q4

2018

Q3

Launch

Series C

$30.5 MM$30M

$20M

Regulatory / Clinical

Series D

$35 MM

M&A / IPO

$50 MM$40M

151 12/4/2009

Proof of Concept

Pilot Studie

s

IC and Processing Patents

Marketable Product

Provisional Patent

Beta-Versio

n Testin

g

Application and

System Patents

IRB / IDE

Clinical Results

Second Release

Initial Product Launch

Specific Codes (Cat. I CPT / APC)

Non-Specific Codes

1st

Release Test

2nd Release Test

Publication

Post-Market Clinical Studies

Beta Prototype

US Interim Trials

FDA – Class II – 510 (k) with Clinical Trials

Publication

Financial / Operations Timeline

Cat III CPT

US Pivotal Clinical Trials

Laboratory

Prototype

Technology

Licensing

MammOpticsMammOptics

Financial

timeline

Page 152: Steve Blank "Entrepreneurial education"

$10M

$15M

2012

Ca

sh

Re

se

rve

Clin

ica

l M

ile

sto

ne

s

$5M

Initialize

De

sig

n

Mile

sto

ne

sR

eg

ula

tory

/ IP

M

ile

sto

ne

s

Q1 Q2 Q3 Q4

2013

Q1 Q2 Q3 Q4

2014

Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4

2015 2016 2017

Q1 Q2Q1 Q2 Q3 Q4

2018

Q3

$30M

$20M

$40M

152 12/4/2009

Proof of Concept

Provisional Patent

Financial / Operations Timeline

Technology

Licensing

MammOpticsMammOptics

Page 153: Steve Blank "Entrepreneurial education"

$10M

$15M

2012

Series A

$3.5 MM

Ca

sh

Re

se

rve

Clin

ica

l M

ile

sto

ne

s

$5M

Initialize

De

sig

n

Mile

sto

ne

sR

eg

ula

tory

/ IP

M

ile

sto

ne

s

Q1 Q2 Q3 Q4

2013

Q1 Q2 Q3 Q4

2014

Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4

2015 2016

System

2017

Q1 Q2Q1 Q2 Q3 Q4

2018

Q3

$30M

$20M

$40M

153 12/4/2009

Proof of Concept

Provisional Patent

Beta-Versio

n Testin

g

Laboratory

Prototype

Beta Prototype

Technology

Licensing

Financial / Operations Timeline

Pilot Studie

s

MammOpticsMammOptics

Page 154: Steve Blank "Entrepreneurial education"

$10M

$15M

2012

Series A

$3.5 MM

Ca

sh

Re

se

rve

Clin

ica

l M

ile

sto

ne

s

$5M

De

sig

n

Mile

sto

ne

sR

eg

ula

tory

/ IP

M

ile

sto

ne

s

Q1 Q2 Q3 Q4

2013

Q1 Q2 Q3 Q4

2014

Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4

2015 2016

Series B

$9 MM

System

2017

Q1 Q2Q1 Q2 Q3 Q4

2018

Q3

$30M

$20M

$40M

154 12/4/2009

IC and Processing Patents

Marketable Product

Beta-Versio

n Testin

g

Application and

System Patents

IRB / IDE

Beta Prototype

Financial / Operations Timeline

Pilot Studie

s

Regulatory / Clinical

Laboratory

Prototype

MammOpticsMammOptics

Page 155: Steve Blank "Entrepreneurial education"

$10M

$15M

2012

Ca

sh

Re

se

rve

Clin

ica

l M

ile

sto

ne

s

$5M

De

sig

n

Mile

sto

ne

sR

eg

ula

tory

/ IP

M

ile

sto

ne

s

Q1 Q2 Q3 Q4

2013

Q1 Q2 Q3 Q4

2014

Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4

2015 2016

Series B

$9 MM

System

2017

Q1 Q2Q1 Q2 Q3 Q4

2018

Q3

Series C

$30.5 MM$30M

$20M

Regulatory / Clinical

$40M

155

IC and Processing Patents

Application and

System Patents

IRB / IDE

Cat III CPT

Second Release

1st

Release Test

US Interim Trials US Pivotal Clinical Trials

Publication

Financial / Operations Timeline

Pilot Studie

s

MammOpticsMammOptics

Page 156: Steve Blank "Entrepreneurial education"

$10M

$15M

2012

Ca

sh

Re

se

rve

Clin

ica

l M

ile

sto

ne

s

$5M

De

sig

n

Mile

sto

ne

sR

eg

ula

tory

/ IP

M

ile

sto

ne

s

Q1 Q2 Q3 Q4

2013

Q1 Q2 Q3 Q4

2014

Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4

2015 2016 2017

Q1 Q2Q1 Q2 Q3 Q4

2018

Q3

Launch

Series C

$30.5 MM$30M

$20M

Regulatory / Clinical

Series D

$35 MM

$40M

156 12/4/2009

Clinical Results

Second Release

Initial Product Launch

Non-Specific Codes

2nd Release Test

Publication

US Interim Trials

FDA – Class II – 510 (k) with Clinical Trials

Publication

Financial / Operations Timeline

US Pivotal Clinical Trials

MammOpticsMammOptics

Page 157: Steve Blank "Entrepreneurial education"

$10M

$15M

2012

Ca

sh

Re

se

rve

Clin

ica

l M

ile

sto

ne

s

$5M

De

sig

n

Mile

sto

ne

sR

eg

ula

tory

/ IP

M

ile

sto

ne

s

Q1 Q2 Q3 Q4

2013

Q1 Q2 Q3 Q4

2014

Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4

2015 2016 2017

Q1 Q2Q1 Q2 Q3 Q4

2018

Q3

Launch

$30M

$20M

Regulatory / Clinical

Series D

$35 MM

M&A / IPO

$50 MM$40M

12/4/2009

Clinical Results

Initial Product Launch

Specific Codes (Cat. I CPT / APC)

Non-Specific Codes

Publication

Post-Market Clinical Studies

FDA – Class II – 510 (k) with Clinical Trials

Financial / Operations TimelineMammOpticsMammOptics

Page 158: Steve Blank "Entrepreneurial education"

$10M

$15M

2012

Series A

$3.5 MM

Ca

sh

Re

se

rve

Clin

ica

l M

ile

sto

ne

s

$5M

Initialize

De

sig

n

Mile

sto

ne

sR

eg

ula

tory

/ IP

M

ile

sto

ne

s

Q1 Q2 Q3 Q4

2013

Q1 Q2 Q3 Q4

2014

Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4

2015 2016

Series B

$9 MM

System

2017

Q1 Q2Q1 Q2 Q3 Q4

2018

Q3

Launch

Series C

$30.5 MM$30M

$20M

Regulatory / Clinical

Series D

$35 MM

M&A / IPO

$50 MM$40M

158 12/4/2009

Proof of Concept

Pilot Studie

s

IC and Processing Patents

Marketable Product

Provisional Patent

Beta-Versio

n Testin

g

Application and

System Patents

IRB / IDE

Clinical Results

Second Release

Initial Product Launch

Specific Codes (Cat. I CPT / APC)

Non-Specific Codes

1st

Release Test

2nd Release Test

Publication

Post-Market Clinical Studies

Beta Prototype

US Interim Trials

FDA – Class II – 510 (k) with Clinical Trials

Publication

Financial / Operations Timeline

Cat III CPT

US Pivotal Clinical Trials

Laboratory

Prototype

Technology

Licensing

MammOpticsMammOptics

Page 159: Steve Blank "Entrepreneurial education"

MammOptics

Business Model Canvas 4 of 4

OB/GYNs

PCPs

Direct Sales to

hospitals

Distributor

Online

Strong clinical

data

Training

Maintenance

Conferences

CME courses

Product Development

Clinical trials

Operating Costs

Marketing Costs

Per use fees

Product

Development

IP

Clinical trials

FDA

Reimburseme

nt Publishing

IP

Leading doctors

Technical

Expertise

KOLs

3rd party

manufacturers

Distributors

Breast Cancer

Foundations

ACOG

ACS

Clinical trial

designer

Doctors:

Earlier

detection

Price

Accuracy

Immediate

Results

Patients:

Radiation Free

Non-Invasive

Page 160: Steve Blank "Entrepreneurial education"

MammOptics

Business Model Canvas 4 of 4

Earlier detection

Non invasive

Price

Accuracy

Immediate Results

OB/GYNs

PCPs

Direct Sales to

hospitals

Distributor

Online

Strong clinical

data

Training

Maintenance

Conferences

CME courses

Product Development

Clinical trials

Operating Costs

Marketing Costs

Per use fees

Product

Development

IP

Clinical trials

FDA

Reimburseme

nt Publishing

IP

Leading doctors

Technical

Expertise

KOLs

3rd party

manufacturers

Breast Cancer

Foundations

ACOG

ACS

Clinical trial

designer

Page 161: Steve Blank "Entrepreneurial education"

Radiation-free

Earlier detection

Non invasive

Pioneering

Doctors

Hospitals

Direct Sales to

hospitals

Strong clinical

data

Training

Maintenance

Product Development

Clinical trials

Operating Costs

Capital Equipment Sales

and disposable item

Product

Development

IP

Clinical trials

FDA

IP

Leading doctors

Technical

Expertise

Hospitals

Leading doctors

3rd party

manufacturers

Distributors

MammOptics

Business Model Canvas 1

Page 162: Steve Blank "Entrepreneurial education"

Radiation-free

Earlier detection

Non invasive

Pioneering

Doctors

Hospitals

Direct Sales to

hospitals

Strong clinical

data

Training

Maintenance

Product Development

Clinical trials

Operating Costs

Capital Equipment Sales

and disposable item

Product

Development

IP

Clinical trials

FDA

IP

Leading doctors

Technical

Expertise

Hospitals

Leading doctors

3rd party

manufacturers

Distributors

Research

Hospitals

MammOptics

Business Model Canvas 2

Page 163: Steve Blank "Entrepreneurial education"

Pioneering

Doctors

Hospitals

Direct Sales to

hospitals

Strong clinical

data

Training

Maintenance

Product Development

Clinical trials

Operating Costs

Capital Equipment Sales

and disposable item

Product

Development

IP

Clinical trials

FDA

IP

Leading doctors

Technical

Expertise

Hospitals (Capital

Spending

Committee)

Leading doctors

3rd party

manufacturers

Distributors

Research

Hospitals

Doctors:

Earlier

detection

Price

Accuracy

Patients:

Radiation Free

Non-Invasive

MammOptics

Business Model Canvas 3

Page 164: Steve Blank "Entrepreneurial education"

Pioneering

Doctors

Hospitals

OB/GYNs

PCPs

Direct Sales to

hospitals

Strong clinical

data

Training

Maintenance

Product Development

Clinical trials

Operating Costs

Capital Equipment Sales

and disposable item

Product

Development

IP

Clinical trials

FDA

IP

Leading doctors

Technical

Expertise

Hospitals (Capital

Spending

Committee)

Leading doctors

3rd party

manufacturers

Distributors

Research

Hospitals

Breast Cancer

Foundations

Doctors:

Earlier

detection

Price

Accuracy

Immediate

Results

Patients:

Radiation Free

Non-Invasive

MammOptics

Business Model Canvas 4

Page 165: Steve Blank "Entrepreneurial education"

OB/GYNs

PCPs

Direct Sales to

hospitals

Distributor

Strong clinical

data

Training

Maintenance

Conferences

CME courses

Product Development

Clinical trials

Operating Costs

Marketing Costs

Capital Equipment Sales

and disposable item

Product

Development

IP

Clinical trials

FDA

Reimburseme

ntPublishing

IP

Leading doctors

Technical

Expertise

Leading doctors

Key Opinion

Leaders

3rd party

manufacturers

Distributors

Breast Cancer

Foundations

ACOG

ACS

Doctors:

Earlier

detection

Price

Accuracy

Patients:

Radiation Free

Non-Invasive

MammOptics

Business Model Canvas 5

Page 166: Steve Blank "Entrepreneurial education"

OB/GYNs

PCPs

Direct Sales to

hospitals

Distributor

Strong clinical

data

Training

Maintenance

Conferences

CME courses

Product Development

Clinical trials

Operating Costs

Marketing Costs

Capital Equipment Sales

and disposable item

Per use fees

Product

Development

IP

Clinical trials

FDA

Reimburseme

nt Publishing

IP

Leading doctors

Technical

Expertise

KOLs

3rd party

manufacturers

Distributors

Breast Cancer

Foundations

ACOG

ACS

Doctors:

Earlier

detection

Price

Accuracy

Immediate

Results

Patients:

Radiation Free

Non-Invasive

MammOptics

Business Model Canvas 6

Page 167: Steve Blank "Entrepreneurial education"

OB/GYNs

PCPs

Direct Sales to

hospitals

Distributor

Strong clinical

data

Training

Maintenance

Conferences

CME courses

Product Development

Clinical trials

Operating Costs

Marketing Costs

Per use fees

Product

Development

IP

Clinical trials

FDA

Reimburseme

nt Publishing

IP

Leading doctors

Technical

Expertise

KOLs

3rd party

manufacturers

Distributors

Breast Cancer

Foundations

ACOG

ACS

Clinical trial

designer

Doctors:

Earlier

detection

Price

Accuracy

Immediate

Results

Patients:

Radiation Free

Non-Invasive

MammOptics

Business Model Canvas 7

Page 168: Steve Blank "Entrepreneurial education"

OB/GYNs

PCPs

Direct Sales to

hospitals

Distributor

Strong clinical

data

Training

Maintenance

Conferences

CME courses

Product Development

Clinical trials

Operating Costs

Marketing Costs

Per use fees

Product

Development

IP

Clinical trials

FDA

Reimburseme

nt Publishing

IP

Leading doctors

Technical

Expertise

KOLs

3rd party

manufacturers

(local)

Breast Cancer

Foundations

ACOG

ACS

Clinical trial

designer

Doctors:

Earlier

detection

Price

Accuracy

Immediate

Results

Patients:

Radiation Free

Non-Invasive

MammOptics

Business Model Canvas 8

Page 169: Steve Blank "Entrepreneurial education"

OB/GYNs

PCPs

Direct Sales to

hospitals

Distributor

Strong clinical

data

Training

Maintenance

Conferences

CME courses

Product Development

Clinical trials

Operating Costs

Marketing Costs

Per use fees

Product

Development

IP

Clinical trials

FDA

Reimburseme

nt Publishing

IP

Leading doctors

Technical

Expertise

KOLs

3rd party

manufacturers

(local)

Breast Cancer

Foundations

ACOG

ACS

Clinical trial

designer

Doctors:

Earlier

detection

Price

Accuracy

Immediate

Results

Patients:

Radiation Free

Non-Invasive

MammOptics

Business Model Canvas 9

Page 170: Steve Blank "Entrepreneurial education"

Blog Your Progress

Page 171: Steve Blank "Entrepreneurial education"

How?

• Customer Development– The Process

• Narrative– Interviews

– Surveys

– Videos

– Prototypes

• Business Model Canvas– Scorekeeping

• Real-time Feedback

• Physical Reality Checks– Skype

– Face-to-face

Page 172: Steve Blank "Entrepreneurial education"

We Made Students

Blog Their Progress

It Changed Everything

Page 173: Steve Blank "Entrepreneurial education"

Interview

Page 174: Steve Blank "Entrepreneurial education"

Photos Videos

Page 175: Steve Blank "Entrepreneurial education"

Surveys

Page 176: Steve Blank "Entrepreneurial education"

Interview

& Photos

Page 177: Steve Blank "Entrepreneurial education"

Competitive

Analysis

Page 178: Steve Blank "Entrepreneurial education"

Key Findings

Page 179: Steve Blank "Entrepreneurial education"

A/B Test

Results

Page 180: Steve Blank "Entrepreneurial education"

Key Question

Page 181: Steve Blank "Entrepreneurial education"

Strategy

Page 182: Steve Blank "Entrepreneurial education"

Business Model Canvas as

the Scorecard

Page 183: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

Business School Versus

Entrepreneurship School

Entrepreneurship School

-Hypothesis testing

- Business Model design

- Customer Development

- Agile Development

- Metrics

- Venture Finance

- Design Thinking

-Execution

- Accounting

- Products

- Engineering

- Management

- Administrative

Business School

Page 184: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

Courses

- Lean Launchpad

- Customer/Agile Development

- Business Model Design

- Entrepreneurial Management

- Creativity and Innovation

- Entrepreneurial Finance

- User-centric design

Business School

Business School Versus

Entrepreneurship Courses

Entrepreneurship School

Courses

- Managerial Finance/Accounting

- Managing Groups and Teams

- Financial Accounting

- Operations

- Modeling for Optimization

- Global Value Chain Strategies

Page 185: Steve Blank "Entrepreneurial education"

ScalableStartup

Large Company

Transition

Courses

- Lean Launchpad

- Customer/Agile Development

- Business Model Design

- Entrepreneurial Management

- Creativity and Innovation

- Entrepreneurial Finance

- User-centric design

Business School

Business School Versus

Entrepreneurship Courses

Entrepreneurship School

I teach this

Page 186: Steve Blank "Entrepreneurial education"

E-School

•20th century focus on physical goods

• East coast manufacturing-centric

• East coast B-School-centric

• 21st century focus on virtual and physical goods

and channels

• West coast engineering school-centric

Page 187: Steve Blank "Entrepreneurial education"

One More Thing

Page 188: Steve Blank "Entrepreneurial education"

Adopted by the U.S. Government

Page 189: Steve Blank "Entrepreneurial education"

Thanks

www.steveblank.com