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Spontaneous coronary artery dissection: a complete resolution with medical treatment Abdullah Sayied Abdullah, Hisham Ibrahim, Thomas J Kiernan Department of Cardiology, University Hospital Limerick, Limerick, Ireland Correspondence to Dr Abdullah Sayied Abdullah, [email protected] Accepted 25 September 2014 To cite: Abdullah AS, Ibrahim H, Kiernan TJ. BMJ Case Rep Published online: [ please include Day Month Year] doi:10.1136/bcr-2014- 204153 DESCRIPTION A 28-year-old man, with no risk factors for coron- ary artery disease (CAD) and with a history of recent anabolic steroid use and intense anaerobic exercise, presented with chest pain, inferior T Wave changes and elevated troponin. A non-ST segment elevation myocardial infarction (NSTEMI) was diagnosed. Coronary angiography revealed spon- taneous right coronary artery (RCA) dissection extending from proximal to distal (video 1 and gure 1). The patient was managed medically with aspirin, clopidogrel and low molecular weight heparin. Repeat angiography after 1 week revealed almost complete resolution of the spontaneous RCA dis- section (video 2 and gure 2). Spontaneous coronary artery dissection is an unusual cause of myocardial infarction in young patients with low risk of atherosclerotic CAD. Causes are unknown, but it has been associated with the postpartum period, renal bromuscular dysplasia and connective tissue diseases. 1 2 Management is difcult, however, medical treat- ment is reported to be effective but percutaneous coronary intervention is associated with poorer outcome. 12 The potential problem during coron- ary bypass graft surgery is identifying and grafting the true lumen rather than the false lumen. This case illustrates the success of conservative treatment in cases of spontaneous coronary artery dissection. It also draws attention to the use of Figure 1 Right coronary artery dissection with double lumen appearance (arrow). Figure 2 Image of right coronary artery after resolution. Video 1 RCA coronary angiography: RCA dissection with poor distal ow. Video 2 RCA coronary angiography after 1 week of medical therapy. Abdullah AS, et al. BMJ Case Rep 2014. doi:10.1136/bcr-2014-204153 1 Images in on 16 July 2020 by guest. Protected by copyright. http://casereports.bmj.com/ BMJ Case Reports: first published as 10.1136/bcr-2014-204153 on 15 October 2014. Downloaded from

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  • Spontaneous coronary artery dissection: a completeresolution with medical treatmentAbdullah Sayied Abdullah, Hisham Ibrahim, Thomas J Kiernan

    Department of Cardiology,University Hospital Limerick,Limerick, Ireland

    Correspondence toDr Abdullah Sayied Abdullah,[email protected]

    Accepted 25 September 2014

    To cite: Abdullah AS,Ibrahim H, Kiernan TJ. BMJCase Rep Published online:[please include Day MonthYear] doi:10.1136/bcr-2014-204153

    DESCRIPTIONA 28-year-old man, with no risk factors for coron-ary artery disease (CAD) and with a history ofrecent anabolic steroid use and intense anaerobicexercise, presented with chest pain, inferior T Wavechanges and elevated troponin. A non-ST segmentelevation myocardial infarction (NSTEMI) wasdiagnosed. Coronary angiography revealed spon-taneous right coronary artery (RCA) dissectionextending from proximal to distal (video 1 andfigure 1).The patient was managed medically with aspirin,

    clopidogrel and low molecular weight heparin.Repeat angiography after 1 week revealed almostcomplete resolution of the spontaneous RCA dis-section (video 2 and figure 2).

    Spontaneous coronary artery dissection is anunusual cause of myocardial infarction in youngpatients with low risk of atherosclerotic CAD.Causes are unknown, but it has been associatedwith the postpartum period, renal fibromusculardysplasia and connective tissue diseases.1 2

    Management is difficult, however, medical treat-ment is reported to be effective but percutaneouscoronary intervention is associated with pooreroutcome.1 2 The potential problem during coron-ary bypass graft surgery is identifying and graftingthe true lumen rather than the false lumen.This case illustrates the success of conservative

    treatment in cases of spontaneous coronary arterydissection. It also draws attention to the use of

    Figure 1 Right coronary artery dissection with doublelumen appearance (arrow).

    Figure 2 Image of right coronary artery afterresolution.

    Video 1 RCA coronary angiography: RCA dissectionwith poor distal flow.

    Video 2 RCA coronary angiography after 1 week ofmedical therapy.

    Abdullah AS, et al. BMJ Case Rep 2014. doi:10.1136/bcr-2014-204153 1

    Images in…

    on 16 July 2020 by guest. Protected by copyright.

    http://casereports.bmj.com

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    MJ C

    ase Reports: first published as 10.1136/bcr-2014-204153 on 15 O

    ctober 2014. Dow

    nloaded from

    http://crossmark.crossref.org/dialog/?doi=10.1136/bcr-2014-204153&domain=pdf&date_stamp=2014-10-15http://casereports.bmj.comhttp://casereports.bmj.com/

  • anabolic steroids and intense anabolic exercise as possibleassociations with spontaneous coronary artery dissection.

    Learning points

    ▸ Consider coronary artery dissection in young patients withacute coronary syndrome.

    ▸ Medical management of coronary artery dissection iseffective.

    ▸ Detailed history is important to elucidate risk factors forcoronary artery disease.

    Contributors ASA wrote the original manuscript and edited the final one, andtreated the patient. HI edited the manuscript and participated in the management ofthe patient. TK is the principal physician in this patient treatment, and edited themanuscript.

    Competing interests None.

    Patient consent Obtained.

    Provenance and peer review Not commissioned; externally peer reviewed.

    REFERENCES1 Tweet MS, Hayes SN, Pitta SR, et al. Clinical features, management, and prognosis of

    spontaneous coronary artery dissection. Circulation 2012;126:579–88.2 Hayes SN. Spontaneous coronary artery dissection (SCAD): new insights into this

    not-so-rare condition. Tex Heart Inst J 2014;41:295–8.

    Copyright 2014 BMJ Publishing Group. All rights reserved. For permission to reuse any of this content visithttp://group.bmj.com/group/rights-licensing/permissions.BMJ Case Report Fellows may re-use this article for personal use and teaching without any further permission.

    Become a Fellow of BMJ Case Reports today and you can:▸ Submit as many cases as you like▸ Enjoy fast sympathetic peer review and rapid publication of accepted articles▸ Access all the published articles▸ Re-use any of the published material for personal use and teaching without further permission

    For information on Institutional Fellowships contact [email protected]

    Visit casereports.bmj.com for more articles like this and to become a Fellow

    2 Abdullah AS, et al. BMJ Case Rep 2014. doi:10.1136/bcr-2014-204153

    Images in…

    on 16 July 2020 by guest. Protected by copyright.

    http://casereports.bmj.com

    /B

    MJ C

    ase Reports: first published as 10.1136/bcr-2014-204153 on 15 O

    ctober 2014. Dow

    nloaded from

    http://casereports.bmj.com/

    Spontaneous coronary artery dissection: a complete resolution with medical treatmentDescriptionReferences