Solute Carrier Antibodies {

International Corporationl ife. science.discovery.™

15A Constitution Way, Woburn MA 01801,USA • T: 800.200.5459 F: 781.939.6963 • mblintl.com

• Analyze the protein of interest for your solute carrier distribution

• Highly specific antibodies

• Verified for Western Blotting and Immunohistochemistry (Analysis of cells trasnfected with full length SLC cDNA)

Solute Carrier

15A Constitution Way, Woburn MA 01801,USA • T: 800.200.5459 F: 781.939.6963 • mblintl.com

Code Number Product Name ApplicationBMP002 Anti-HP1beta (Human) pAb ICC, IHC, IPP, WBBMP004 Anti-mSIN3A pAb (Human) pAb ICC, IHC, IPP, WBBMP032 Anti-SLC11A1 (NRANP1) (Human) pAb FCM, ICC, IHC, WBBMP063 Anti-SLC11A2 (DMT1) (Human) pAb FCM, ICC, IHCBMP073 Anti-SLC17A6 (VGLUT2) (Human) pAb IHC, WBBMP078 Anti-SLC17A7 (VGLUT1) (Human) pAb FCM, ICC, IHCBMP079 Anti-SLC17A9 isoform 2 (VNUT) (Human) pAb FCM, IHCBMP010 Anti-SLC1A1 (EAAC1/EAAT3) (Human) pAb IHC, WBBMP069 Anti-SLC1A2 (EAAT2) (Human) pAb FCM, ICC, IHCBMP028 Anti-SLC1A4 (ASCT1) (Human) pAb FCM, ICC, IHC, WBBMP064 Anti-SLC22A12 (URAT1) (Human) pAb FCM, ICC, IHCBMP065 Anti-SLC22A13 (ORCTL3/OCTL1) (Human) pAb FCM, ICC, IHCBMP076 Anti-SLC22A5 (OCTN2) (Human) pAb FCM, ICC, IHCBMP084 Anti-SLC26A7 (SUT2) (Human) pAb FCM, ICC, IHCBMP025 Anti-SLC2A11 (GLUT11) (Human) pAb FCM, ICC, IHC, WBBMP026 Anti-SLC2A13 (HMIT) (Human) pAb FCM, ICC, IHC, WBBMP027 Anti-SLC2A9 (GLUT9) (Human) pAb FCM, ICC, IHC, WBBMP094 Anti-SLC30A3 (ZNT3) (Human) pAb FCM, IHC, WBBMP033 Anti-SLC40A1 (FPN1) (Human) pAb FCM, ICC, IHC, WBBMP098 Anti-SLC43A1 (LAT3) (Human) pAb IHC, WBBMP071 Anti-SLC4A10 (NCBE) (Human) pAb FCM, ICC, IHCBMP059 Anti-SLC4A3 (AE3) (Human) pAb FCM, ICC, IHCBMP051 Anti-SLC6A13 (GAT2) (Human) pAb FCM, ICC, IHC, WBBMP052 Anti-SLC6A14 (ATB0+) (Human) pAb FCM, ICC, IHC, WBBMP053 Anti-SLC6A19 (B0AT1) (Human) pAb FCM, ICC, IHCBMP029 Anti-SLC6A2 (NET) (Human) pAb FCM, ICC, IHC, WBBMP016 Anti-SLC6A7 (PROT) (Human) pAb IHC, WBBMP056 Anti-SLC7A10 (Asc-1) (Human) pAb FCM, ICC, IHCBMP040 Anti-SLC7A3 (CAT3) (Human) pAb FCM, ICC, IHC, WBBMP041 Anti-SLC7A8 (LAT2) (Human) pAb FCM, ICC, IHC, WBBMP021 Anti-SLC7A9 (B0,+AT) (Human) pAb FCM, ICC, IHC, WBBMP062 Anti-SLC8A2 (NCX2) (Human) pAb FCM, ICC, IHC, WBBMP043 Anti-SLC9A7 (NHE7) (Human) pAb FCM, ICC, IHC, WBBMP061 Anti-SLC9A9 (NHE9) (Human) pAb FCM, ICC, IHC, WB

Many important nutrients, including glucose and amino acids, are water soluble. Transporter proteins enable water soluble nutrients to cross the lipid double- membrane and enter the cell. These membrane trans-porters form a large and diverse family of proteins which are highly selective for specific solutes, called solute carriers (SLC). Transporters can be divided into pumps (ATP binding cassette) which consume energy by hydrolyzing ATP, and carriers which facilitate the diffusion of solutes without use of ATP. The human genome encodes 49 known pumps and 360 solute carrier proteins. Transporters are expressed throughout the body, but are most abundant in kidney, liver and the nervous system. Among the 40 families of solute carriers (SLC), 26 families are mostly expressed in kidney, and many types of kidney disease (tubular acidosis, cystinuria, hereditary renal glycosuria) have been associated with mutations of SLC and related genes.

Solute Carriers and Transporters