e-NEWS LETTERSINHGAD COLLEGE OF PHARMACYSinhgad Technical Education Society,s

Volume 1 Issue 2 SEPT-NOV/2019-20

Editorial Board:

Dr. Mrs. Nisharani Ranpise

Dr. Satish Mandlik

Mr. Prashik Dudhe

Advisory Board:

Dr. Sadhana S. Raut

Dr. A. M. Avachat

Dr. M. G. Gambhire

Dr. H. K. Jain

eNews Letter Co-ordinator:

Dr. Sadhana S. Raut

SCOP- eNewsletter | 1An Official Publication:Sinhgad College of Pharmacy, Pune - 411041Phone No:020-24354720 Email : scop@sinhgad.edu

www.sinhgad.edu

A substance that could cause cancer has been found in some ranitidine heartburn and ulcer medicines, including the brand-name drug Zantac, and the source of this contamination is being investigated, the U.S. Food and Drug Administration says. While preliminary tests found low levels of the nitrosamine impurity N-nitrosodimethylamine (NDMA) in some ranitidine products, the FDA said this does not mean patients taking the drugs should stop using them now. NDMA is the same contaminant found in many brands of blood pressure and heart failure medicines during the past year, leading to recalls. Patients who are taking prescription ranitidine and want to stop using it should discuss alternatives with their health care provider, the FDA advised. Those taking over-the-counter (OTC) ranitidine could switch to other OTC medicines.Reference: https://www.fda.gov

Zantac Heartburn Drug May Contain Carcinogen: FDA

Oral lichen planus is an autoimmune condition that is chronic inflammatory in nature. The name lichen comes from a plant that grows mostly on rocks and has a mossy, web-like appearance. Oral lichen planus appears like red and white lacy patches or opens sore, which cause a burning sensation and pain. The condition causes swelling, irritation, and redness, primarily in the mucous membranes inside the mouth. People suffering from this disease also have difficulty in eating and swallowing their food. Lichen planus is a type of skin disease and is not only limited to the mouth but can also occur in different body parts like hair, nails, ears and even the genital parts. Homeopathy claims to have a treatment for the ailment. Basically, 2 per cent of the entire population of the world is affected by this condition. This disease is usual in people of all age groups but is common in women above the age of 40. However, the reason why women are mostly affected by this disorder is still unknown and various researches are underway to find out the cause.Reference: https://www.healthline.com

Oral lichen planus

Our Inspiration

Dr.(Mrs.) Sunanda M. NavaleSecretary

Mrs. Rachana Navale AshtekarVice-President (Admin)

Prof. M. N. NavalePresident

Mr. Rohit M. Navale Vice-President (HR)

ndWelcome to the 2 issue of the college quarterly news letter.

In this issue we have focused on current trends in pharmaceutical sciences and technology. The highlights of college activities in previous quarter viz curricular, co-curricular and extracurricular activities are also included. The students and faculties were actively participated in various co-curricular and extracurricular activities. Our college has well established IQAC cell which take quality initiatives in educational development of students. I request all the readers do reach us with social media as well as check our year round website.

Thank you for joining us.

Dr. K. N. GujarPrincipal

SCOP- eNewsletter | 2 An Official Publication:Sinhgad College of Pharmacy, Pune - 411041Phone No:020-24354720 Email : scop@sinhgad.edu

Prescribers should be alert for neuropsychiatric reactions in patients taking montelukast and carefully consider the benefits and risks of continuing treatment if they occur. A range of neuropsychiatric reactions has been reported in association with montelukast. Among these are: sleep disturbances, depression and agitation (may affect up to 1 in 100 people taking montelukast); disturbances of attention or memory (up to 1 in 1,000 people); and very rarely, hallucinations and suicidal behaviour (up to 1 in 10,000 people).Reference: https://www.gov.uk

New Drugs Approved in September to November 2019

There are many types of honey and all of them contain enzymes and nutrients that have a variety of health benefits. Honey has been used for medicinal purposes throughout history. It works as a natural sweetener, helps in soothing sore throat and works as an immunity booster.The taste, colour and exact nutrient of different types of honey depends on where the bees collect it from. It also depends on the type of flowers honey from. White honey has milder flavour as compared to darker honey. Flowers that produce white honey include, sage. Alfalfa, fireweed and white clover.Despite the name, white honey isn't exactly white in colour. But it's lighter in colour than traditional honey. There is another form of white honey called kiawe honey, which is a rare one. It comes from the kiawe trees in Hawaii. This honey is collected as a liquid and it

naturally crystallizes to a smooth, creamy texture, which makes it perfect for spreading on bread or cakes. This white kiawe honey is sold as raw honey.White honey provides you with more than just calories. It has vitamins and minerals including B vitamins, copper, calcium, potassium, phosphorus and zinc. It also a powerhouse of antioxidants.The antioxidants in white honey protect your body against multiple diseases. It improves your gut health and thus supports digestion. It also acts as a cold suppressant and helps in relieving pain.Reference: https://www.healthline.com

What is white honey

Sr. Name of Drug Company In treatment of

1 Gvoke (glucagon) Ready-to-Use Injection Xeris Pharmaceuticals, Inc.

Hypoglycemia

2 Ibsrela (tenapanor) Tablets Ardelyx, Inc Irritable Bowel Syndrome

3 Rybelsus (semaglutide) Tablets Novo Nordisk Diabetes Type 2

4 Jynneos (smallpox and monkeypox vaccine) Injection

Bavarian Nordic Prevention of Smallpox; Prevention of Monkeypox

5 Aklief (trifarotene) Topical Cream Galderma Acne

6 Bonsity (teriparatide) Injection - formerly PF708

Pfenex Inc Osteoporosis

7 Scenesse (afamelanotide) Implant Clinuvel Pharmaceuticals Ltd.

Prevention of Phototoxicity in Erythropoietic Protoporphyria

8 Beovu (brolucizumab-dbll) Injection Novartis Macular Degeneration

9 Quzyttir (cetirizine hydrochloride) Injection TerSera Therapeutics LLC

Urticaria

10 Reyvow (lasmiditan) Tablets Eli Lilly and Company Migraine

11 Secuado (asenapine) Transdermal System Noven Pharmaceuticals, Inc.

Schizophrenia

Montelukast (Singulair): Reminder of the risk of neuropsychiatric reactions

SCOP@enews

SCOP- eNewsletter | 3An Official Publication:Sinhgad College of Pharmacy, Pune - 411041Phone No:020-24354720 Email : scop@sinhgad.edu

Sr. Name of Drug Company In treatment of

12 Amzeeq (minocycline) Topical Foam Foamix Pharmaceuticals

Acne

13 Trikafta (elexacaftor/tezacaftor/ivacaftor and ivacaftor) Tablets

Vertex Pharmaceuticals Incorporated

Cystic Fibrosis

14 Biorphen (phenylephrine hydrochloride) Injection

Eton Pharmaceuticals, Inc

Hypotension

15 Vumerity (diroximel fumarate) Delayed-Release Capsules

Alkermes plc and Biogen

Multiple Sclerosis

16 Talicia (amoxicillin, omeprazole and rifabutin) Delayed-Release Capsules

RedHill Biopharma Ltd. Helicobacter pylori Infection

17 Ziextenzo (pegfilgrastim-bmez) Injection Sandoz Neutropenia Associated with Chemotherapy

18 Reblozyl (luspatercept-aamt) for Injection Celgene Corporation Beta-Thalassemia-Associated Anemia

19 Brukinsa (zanubrutinib) Capsules BeiGene, Ltd. Mantle Cell Lymphoma

20 Fetroja (cefiderocol) Injection Shionogi & Co., Ltd. Complicated Urinary Tract Infections

21 Adakveo (crizanlizumab-tmca) Injection Novartis Prevention of Vaso-Occlusive Crises (VOCs) in Sickle Cell Disease

22 Abrilada (adalimumab-afzb) Injection Pfizer Inc. Rheumatoid Arthritis, Juvenile Idiopathic Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Crohn's Disease -- Maintenance, Ulcerative Colitis, Plaque Psoriasis

23 Givlaari (givosiran) Injection Alnylam Pharmaceuticals, Inc.

Acute Hepatic Porphyria

24 Xcopri (cenobamate) Tablets SK Life Science, Inc Seizures

25 Exservan (riluzole) Oral Film Aquestive Therapeutics, Inc.

Amyotrophic Lateral Sclerosis

26 Oxbryta (voxelotor) Tablets Global Blood Therapeutics, Inc.

Sickle Cell Anemia

27 RediTrex (methotrexate) Injection Cumberland Pharmaceuticals Inc.

Rheumatoid Arthritis, Juvenile Idiopathic Arthritis, Psoriasis

COLLEGE NEWS AND ACTIVITIES

Swayam Online course attended by faculties: Successfully completed NPTEL certificate courses by:

Dr. N. S. Ranpise (Biomedical nanotechnology) Dr. Shilpa Shrotria

Ms. Sonali S. Raut (Introduction to research) (Topper in Biomedical nanotechnology)

Dr. Satish Mandlik (Biomedical nanotechnology). Dr. Sugandha Mulgund (IR Spectroscopy)

Dr. H.K. Jain Dr. S. N. Shrotriya

(Topper in Patents drafting for beginners) (2nd course- Drug delivery principles n Engineering)

Ms. Jyotsna Patil (Health Research Fundamentals) Dr. Sadhana Raut (Computer Aided Drug Design)

Ms. Shubhangi Pawar (Developing Soft Skill and Personality)

SCOP@enews

SCOP- eNewsletter | 4 An Official Publication:Sinhgad College of Pharmacy, Pune - 411041Phone No:020-24354720 Email : scop@sinhgad.edu

SCOP@enews

Awards: Inter collegiate sports organized by SPPU: Attended by Kaushal Rathi (T Y B Pharm) and secured nd th2 rank and selected for Interzonal level (Secured 16 rank). SPPU – Sports (Artistic Gymnastic) in between th th6 and 24 September 2019.

Sinhgad College of Pharmacy students have won a 1st round of Raaj Samman karandak 2019 on Chemical cmoÀ`m.

Under IIC, MHRD, SCOP organized “My story as an Entrepreneur “ by Mr. Vipul Shah to Final Year B. Pharm. & M.Pharm students.

Guest lecture on skill development: Soft skill Development guest lecture delivered by Swami Krupaghananandi on 'Development of self Confidence' Organized by NSS unit of SCOP.

Workshops conducted by SCOP: Mrs Anusha Mallavarapu conducted workshop on “Statistical parameters and its implementation in Clinical and Pharma Research”, Sr Statistical Programmer at Chiltern Clinical Research for M. Pharm. students

thand faculties on 12 Oct 2019.

SCOP organized three days “Lean Six Sigma Green Belt Course” for UG/PG/Ph.D. students and faculties in association with Asian Institute of

th thQuality Management from 9 to 12 October 2019.

Also organized “My story as on Innovator” by Dr. Pravin Badhe. SCOP celebrated “Innovation Day” on thoccasion of Birth anniversary of Dr. A.P.J. Abdul Kalam on 15 Oct 2019 and also conducted

“NEAT Logo Contest”.