shaping the management of parkinsons disease: a comprehensive review of discoveries and clinical...

2nd Annual Shaping the Management of Parkinson’s Disease: A Comprehensive Review of Discoveries and Clinical Trials A Special Weekend CME Program with Parkinson Study Group (PSG) Investigators

in joint sponsorship with Cleveland Clinic

Register Today! www.ccfcme.org/shapingPD14

Registration

Shaping the Management of Parkinson’s Disease: A Comprehensive Review of Discoveries and Clinical Trials

February 8-9, 2014Vdara Hotel & Spa Las Vegas, Nevada

Course 021450 • Office Use Only

Fee ___________ Date ___________

M.O.P. ________ CXL/Fee ________

REGISTER ONLINE

www.ccfcme.org/shapingPD14

Complete the Information Below if Registering by Mail or Fax(please print)

First Name: MI: Last Name: Degree:

Company Name:

Address:

City: State: Zip:

Phone Number: Fax Number:

Specialty: Email Address:

Type of Practice: o Office-Based o Hospital Staff o Resident/Fellow o Other

o I require a vegetarian lunch.

For questions concerning registering, email [email protected] or call 216.448.0777.

*Letter from program director must be received in our office prior to the course to receive this fee. All memberships will be verified before the meeting.

Fee includes: Syllabus, continental breakfasts, refreshment breaks, and Saturday lunch.

PSG Member Non PSG Member

Investigator $100 Physician $200

Coordinator $50 Resident/Fellow* $50

Non-Physician $100

CCF main campus, family health centers, and CCHS community hospital employees (physicians and non-physicians) should register online at the above web address.

Total amount enclosed or to be charged: $___________

Payment Optionso Check Enclosed (Made payable to:) The Cleveland Clinic Educational Foundation P.O. Box 931653 Cleveland, OH 44193-1082

o Credit Card – must register online at www.ccfcme.org/shapingPD14 to pay by credit card.

Cleveland Clinic recognizes the importance of protecting the privacy and security of information provided to us. Therefore, we are no longer requesting credit card data in writing, including on registration forms or faxes. If you would like to register using a credit card please log in to www.ccfcme.org/shapingPD14 or call 216.448.0777 where it will be handled directly by a certified processor.

February 8-9, 2014Vdara Hotel & Spa | Las Vegas, Nevada

The Cleveland Clinic Foundation9500 Euclid Avenue S40Cleveland, OH 44195

NON-PROFIT

U.S. Postage

PAID

Cleveland, Ohio

Permit No. 1918

Regi

ster

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ine

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2nd

Ann

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of

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: A

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www.ccfcme.org/shapingPD14 Register Today!

2nd Annual

Shaping the Management of Parkinson’s Disease:A Comprehensive Review of Discoveries and Clinical Trials A Special Weekend CME Program with Parkinson Study Group (PSG) Investigators



Febr

uary

8-9

, 2014

Vdar

a H

otel

& S

pa |

La

s Ve

gas,

Nev

ada

LocationVdara Hotel & Spa2600 W. Harmon AvenueLas Vegas, NV 89158

Phone: 866.745.7111 or 702.590.2111

Faculty Disclosure

The Cleveland Clinic Foundation Center for Continuing Education has implemented a policy to comply with the current Accreditation Council for Continuing Medical Education Standards for Commercial Support requiring resolution of all faculty conflicts of interest. Faculty declaring a relevant commercial interest will be identified in the activity syllabus.

Registration and Cancellation:Register at www.ccfcme.org/shapingPD14. Deadline for registration for the symposium is 5:00 pm (EST), Tuesday, February 4, 2014. A request for a refund must be received in writing by February 4, 2014. No refunds will be given after February 4, but registration is transferable through February 28. A $25 cancellation fee will be deducted from the refund for all cancellations. If you register by mail, please allow up to three weeks for your registration to be processed. For questions about registration, please call 216-448-0777 or email [email protected].

AccreditationThis activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of the Cleveland Clinic Foundation Center for Continuing Education and Parkinson Study Group. The Cleveland Clinic Foundation Center for Continuing Education is accredited by the ACCME to provide continuing medical education for physicians.

The Cleveland Clinic Foundation Center for Continuing Education designates this live activity for a maximum of 10.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

For the purposes of recertification, the American Nurses Credentialing Center accepts AMA PRA Category 1 Credit™ issued by organizations accredited by the ACCME.

Parking:Free valet parking is available at the Vdara. Self parking is not available.

Americans with Disabilities ActThe Cleveland Clinic Foundation Center for Continuing Education fully intends to comply with the legal requirements of the Americans with Disabilities Act. If you need assistance, please notify Beth Viscomi at 216-444-7591 at least two weeks prior to the activity.


The “modern clinician” is a practical and caring clinician who realizes that therapeutic advancements in Parkinson’s disease are occurring at an unprecedented pace. Much of today’s treatment approach is based on clinical trial findings. Therefore, it is important for clinicians to not only be updated with the clinical trial results, but also to know the hypotheses behind them, the strengths, weaknesses and other findings outside the primary objectives of these clinical trials. This educational program is unique because it intends to discuss the current approaches to the treatment of Parkinson’s disease in the context of the “lessons learned” in clinical trials to date. The program also intends to provide a sneak peak of the future in PD treatment based on planned and on-going clinical trials for delaying disease progression and improving motor and non-motor symptoms of the disorder.

Learning ObjectivesAfter completing this activity, the participant will be able to do the following:

• List the current and emerging treatment approaches for the newly diagnosed Parkinson’s disease (PD) patient

• Describe the current and future treatment options for motor complications in PD

• Recognize and treat the most common nonmotor problems associated with PD

• Explain the role of deep brain stimulation (DBS) surgery and other advanced therapies for PD

• Analyze the strengths and weaknesses of clinical trials and their contribution to today’s evidence-based treatment approach to PD

Target AudienceThis educational activity is intended for all clinicians who treat patients with Parkinson’s disease, including neurologists, internists, family physicians, physician assistants, nurses, and nurse practitioners.

Hotel AccommodationsA block of rooms has been reserved at the Vdara Hotel & Spa until January 16, 2014. To make your reservations, contact the Hotel Reservations Department at 866.745.7767 and 702.590.2767. Please identify yourself as being with the CCN-PSG Meeting for a special rate of $174 plus tax.

General Information

HotelDesigned by a world-class team of architects and designers, CityCenter™ is one of the most unique and ambitious projects in history. This unprecedented collection of talent, design, taste and style is located on 67 acres of the Las Vegas Strip and forever redefines the Las Vegas experience.

Vdara Hotel & Spa™, an internationally inspired all-suite hotel and spa designed for those who love the energy and excitement of Las Vegas but prefer to enjoy it in an exclusive, non-gaming, smoke-free and sustainable environment. Ideally located between ARIA Resort & Casino™ and Bellagio®, Vdara combines contemporary interior spaces with the very latest modern amenities and services.

Crystals at CityCenter™, is the premiere shopping destination in Las Vegas, where the world’s most elite names come together to create an unprecedented shopping experience. Crystals offers patrons an unparalleled tour through a high-end landscape of haute couture, modern dining, stunning architecture and contemporary art. The unique collection of renowned retailers, including Louis Vuitton, Prada, Gucci, Tiffany & Co, Roberto Cavalli and TOM FORD, paired with one-of-kind galleries from artists such as Richard MacDonald and Dale Chihuly combined with signature restaurants from Wolfgang Puck and celebrity restaurateur Eva Longoria redefine the traditional shopping experience.

CoDirectors

Hubert H. Fernandez, MDCo-Chair, PSG Executive Committee Cleveland ClinicCleveland, Ohio

Michael A. Schwarzschild, MD, PhDChair, PSG Executive Committee Harvard Medical School Boston, Massachusetts

Faculty

Alberto J. Espay, MD, MSc, FAANCo-Chair of the PSG Classic Motor Working Group Associate Professor of NeurologyClinical Research Director of the James J. and Joan A. Gardner Center for Parkinson’s Disease and Movement Disorders University of Cincinnati Cincinnati, Ohio

Robert A. Hauser, MD, MBAFormer PSG Executive Committee Member Professor of Neurology, Molecular Pharmacology and PhysiologyDirector, USF Byrd Parkinson’s Disease and Movement Disorders CenterUniversity of South FloridaTampa, Florida

Anthony E. Lang, OC, MD, FRCPC, FAAN, FCAHS, FRSCFormer Chair, PSG Classic Motor Working GroupMovement Disorders Centre Toronto Western HospitalToronto, Ontario, Canada

Peter A. LeWitt, MDChair, PSG Biomarkers Working GroupProfessor of Neurology, Wayne State University School of MedicineDirector, Parkinson’s Disease and Movement Disorders ProgramHenry Ford West Bloomfield HospitalWest Bloomfield, Michigan

Connie Marras, MD, PhDMember, PSG Executive Committee Former Chair, PSG Genetics and Environmental Risk Factors Working GroupAssistant Professor of NeurologyUniversity of TorontoToronto, Ontario, Canada

William G. Ondo, MDProfessor of NeurologyUniversity of Texas Health Science Center at HoustonHouston, Texas

Local Organizing Committee

Eric S. Farbman, MDAssociate Professor of NeurologyDirector of Movement Disorders CenterUniversity of Nevada School of MedicineLas Vegas, Nevada

Ryan R. Walsh MD, PhDDirector, Parkinson’s Disease and Movement Disorders ProgramDirector, Huntington’s Disease Comprehensive ClinicCleveland Clinic Lou Ruvo Center for Brain HealthLas Vegas, Nevada

Ronald F. Pfeiffer, MDFormer Member, PSG Executive Committee Professor and Vice ChairDepartment of NeurologyUniversity of Tennessee Health Science CenterMemphis, Tennessee

Stephen G. Reich, MDProfessor of NeurologyThe Frederick Henry Prince Distinguished Professor in NeurologyDepartment of NeurologyUniversity of Maryland School of MedicineBaltimore, Maryland

Tanya Simuni, MDChair, PSG Classic Motor Working GroupArthur C. Nielsen Professor of Neurology Director, Parkinson’s Disease and Movement Disorders Center Northwestern University Feinberg School of Medicine Chicago, Illinois

Michele Tagliati, MD, FAANProfessor and Vice ChairDepartment of NeurologyDirector of Movement DisordersCedars-Sinai Medical CenterLos Angeles, California

Caroline M. Tanner, MD, PhD, FAANFormer Co-Chair, PSG Executive CommitteeDirector, Clinical Research Parkinson’s InstituteSunnyvale, California

Daniel Weintraub, MDFormer Member, PSG Executive CommitteeAssociate Professor of Psychiatry and Neurology Perelman School of Medicine University of PennsylvaniaPhiladelphia, Pennsylvania

Saturday, February 8th, 2014 7:30 am Continental Breakfast and Registration

8:15 am Welcome and Introduction Hubert Fernandez, MD Michael Schwarzschild, MD, PhD

Session 1: Neuroprotection in Parkinson’s Disease: Where Do We Stand? Moderator: Ryan Walsh, MD, PhD 8:20 am The Challenges We Currently Face Tanya Simuni, MD

9:00 am The Most Promising Leads Michael Schwarzschild, MD, PhD

9:40 am Panel Discussion 9:50 am Refreshment break and Exhibits

An interactive question and answer period is included in each speaker’s allotted time.

Session 2: Initiating Symptomatic Treatment in Early PD: ‘Pull your punches’ vs. ‘Come out swinging’ Moderator: Ryan Walsh, MD, PhD

10:10 am Evidence Supporting Early Levodopa Monotherapy Stephen Reich, MD

10:50 am The Advantages of Delaying Levodopa Therapy Alberto Espay, MD

11:30 am Panel Discussion 11:40 am Lunch and Exhibits

Session 3: Selecting the Optimal Treatment for Motor Fluctuations and Dyskinesias Moderator: Eric Farbman, MD

12:40 pm How Good Are Our Current Treatment Options? William Ondo, MD

1:20 pm Promising Medical Therapies Robert Hauser, MD, MBA

2:00 pm Panel Discussion

Session 4: When to Consider ‘Advanced Therapies’ in Parkinson’s Disease Moderator: Eric Farbman, MD

2:10 pm The Role of Deep Brain Stimulation Surgery and Gene Therapy Michele Tagliati, MD 2:50 pm The Value of Pumps, Patches, Puffs, Infusions and Inhaled Substances Peter LeWitt, MD 3:30 pm Panel Discussion

3:40 pm Refreshment break and Exhibits

Session 5: Autonomic and Sleep Dysfunction in Parkinson’s Disease Moderator: Eric Farbman, MD

4:00 pm The Relevance of Pre-Motor Autonomic and Sleep Dysfunction in PD Connie Marras, MD, PhD 4:40 pm Recognition and Treatment of Autonomic Disturbances in PD Ronald Pfeiffer, MD

5:20 pm Panel Discussion 5:30 pm Adjourn

Sunday, February 9th, 2014

Session 6: Putting It All Together: Lessons from Clinical Trials and Recent Discoveries Moderator: Hubert Fernandez, MD 8:15 am Current Advancements That Have Altered Our Approach to PD Caroline Tanner, MD, PhD 8:55 am Where We Are Headed? Anthony Lang, MD 9:35 am Panel Discussion

9:45 am Refreshment break and Exhibits Session 7: Behavioral and Cognitive Dysfunction in Parkinson’s Disease Moderator: Michael Schwarzschild, MD, PhD 10:05 am Current Challenges, Strategies and Treatment Options Hubert Fernandez, MD 10:45 am Promising Agents and Alternative Therapies and Approaches Daniel Weintraub, MD 11:25 am Panel Discussion

11:40 am Adjourn

Meet the Faculty and Exhibitors: evening reception open to all attendees immediately following


Phone: 866.745.7111 or 702.590.2111

Faculty Disclosure



















General Information




CoDirectors



Faculty







































11:40 am Adjourn





Registration




Fee ___________ Date ___________

M.O.P. ________ CXL/Fee ________

REGISTER ONLINE




Company Name:

Address:

City: State: Zip:











Non-Physician $100








NON-PROFIT

U.S. Postage

PAID

Cleveland, Ohio

Permit No. 1918

Regi

ster

onl

ine

at:

ww

w.cc

fcm

e.or

g/sh

apin

gPD

14

2nd

Ann

ual

Shap

ing

the

Man

agem

ent

of

Park

inso

n’s

Dis

ease

: A

Com

preh

ensi

ve R

evie

w o

f D

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(P

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) In

vest

igat

ors

in jo

int

spon

sors

hip

with

Cle

vela

nd C

linic


2nd Annual




Febr

uary

8-9

, 2014

Vdar

a H

otel

& S

pa |

La

s Ve

gas,

Nev

ada


Phone: 866.745.7111 or 702.590.2111

Faculty Disclosure



















General Information




CoDirectors



Faculty







































11:40 am Adjourn





Registration




Fee ___________ Date ___________

M.O.P. ________ CXL/Fee ________

REGISTER ONLINE




Company Name:

Address:

City: State: Zip:











Non-Physician $100








NON-PROFIT

U.S. Postage

PAID

Cleveland, Ohio

Permit No. 1918

Regi

ster

onl

ine

at:

ww

w.cc

fcm

e.or

g/sh

apin

gPD

14

2nd

Ann

ual

Shap

ing

the

Man

agem

ent

of

Park

inso

n’s

Dis

ease

: A

Com

preh

ensi

ve R

evie

w o

f D

isco

veries

an

d C

linic

al T

rial

s A

Spe

cial

Wee

kend

CM

E Pr

ogra

m w

ith

Park

inso

n Stu

dy G

roup

(P

SG

) In

vest

igat

ors

in jo

int

spon

sors

hip

with

Cle

vela

nd C

linic


2nd Annual




Febr

uary

8-9

, 2014

Vdar

a H

otel

& S

pa |

La

s Ve

gas,

Nev

ada

shaping the management of parkinsons disease: a comprehensive review of discoveries and clinical...

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