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Session 2.1 Overview of Nuclear Applications in Human Health and Nutrition May Abdel-Wahab Director, Division of Human Health Department of Nuclear Applications IAEA

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Page 1: Session 2.1 Overview of Nuclear Applications in Human ... · Nuclear Applications in Human Health . Stable Isotope Techniques in Nutrition ... Nuclear cardiology Renal scans Oncology

Session 2.1

Overview of Nuclear Applications in

Human Health and Nutrition

May Abdel-Wahab

Director, Division of Human Health

Department of Nuclear Applications

IAEA

Page 2: Session 2.1 Overview of Nuclear Applications in Human ... · Nuclear Applications in Human Health . Stable Isotope Techniques in Nutrition ... Nuclear cardiology Renal scans Oncology

2

Division of Human Health enhances the capabilities of MS to address the needs related to the prevention, diagnosis and treatment of health problems

through the application of nuclear and related techniques

Disease prevention

Accurate diagnosis

Precise and Safe Treatment

Treatment of Cancer

Nuclear Applications in Human Health

Page 3: Session 2.1 Overview of Nuclear Applications in Human ... · Nuclear Applications in Human Health . Stable Isotope Techniques in Nutrition ... Nuclear cardiology Renal scans Oncology

Stable Isotope Techniques in Nutrition

• Monitor programmes that: – Promote breastfeeding &

appropriate healthy foods for infants

– Increase vitamins & mineral through food fortification and supplements

– Prevent and treat moderate and severe malnutrition

– Prevent and treat childhood obesity

Exclusive breastfeeding

Vitamin A status; Protein, Micronutrient,

amino acid bioavailability

Body composition, Total energy

expenditure

Page 4: Session 2.1 Overview of Nuclear Applications in Human ... · Nuclear Applications in Human Health . Stable Isotope Techniques in Nutrition ... Nuclear cardiology Renal scans Oncology

Renal Scintigraphy-Tc-99m-MAG3

PET/CT in Use in Neurology

reduced wall motion;inferior scar

Courtesy D.Paez

Use in Cardiology

Nuclear Medicine and Radiology

Anterior wall ischemia

Most Common NM tests: Bone scans Thyroid scintigraphy Lung perfusion and ventilation Nuclear cardiology Renal scans Oncology Neurology and Psychiatry

Page 5: Session 2.1 Overview of Nuclear Applications in Human ... · Nuclear Applications in Human Health . Stable Isotope Techniques in Nutrition ... Nuclear cardiology Renal scans Oncology

Radiation Therapy

• 50% of cancer patients need radiotherapy for treatment

• Radiotherapy can be curative or palliative, alone or combined with chemotherapy or surgery.

Gamma-knife Radiosurgery

Brachytherapy

Robotic Body Radiosurgery

Linac External Beam 3-D/IMRT

Page 6: Session 2.1 Overview of Nuclear Applications in Human ... · Nuclear Applications in Human Health . Stable Isotope Techniques in Nutrition ... Nuclear cardiology Renal scans Oncology

Quality and Dosimetry in Radiation

Medicine

Application of radiation in medicine

Safe & effective

– Development and harmonization of guidance on physical & technical aspects of Quality Assurance

Consistent and accurate

– Development and provision of accurate dosimetry through calibration and audit services

Page 7: Session 2.1 Overview of Nuclear Applications in Human ... · Nuclear Applications in Human Health . Stable Isotope Techniques in Nutrition ... Nuclear cardiology Renal scans Oncology

Added value of the Nuclear Applications

Atun et al Lancet Oncol 2015; 16: 1153–86

Atun et al Lancet Oncol 2015; 16: 1153–86

Page 8: Session 2.1 Overview of Nuclear Applications in Human ... · Nuclear Applications in Human Health . Stable Isotope Techniques in Nutrition ... Nuclear cardiology Renal scans Oncology

Steps in the implementation and use

of Nuclear Techniques

Data bases (DIRAC

and NumDab)

imPACT Missions

Page 9: Session 2.1 Overview of Nuclear Applications in Human ... · Nuclear Applications in Human Health . Stable Isotope Techniques in Nutrition ... Nuclear cardiology Renal scans Oncology

THANK YOU