· sept. 4, 1875.] the british medical yournal. 311 examined. itsaction wasthen comparedwiththat...

7
Sept. 4, 1875.] THE BRITISH MEDICAL YOURNAL. 311 examined. Its action was then compared with that of the hydrochlorates of the chinoline series of bases distilling at higher temperatures, includ- ing such as lepidine, dispoline, tetrahiroline, etc. In the next place, the physiological action of the pyridine series was studied, beginning with pyridine itself, and passing upwards to bases obtained at still higher boiling-points, such as picoline, lutidine, etc. Lastly, the in- vestigation was directed to the action of condensed bases, such as dipyridine, parapicoline, etc.; and the effects of these substances were compared with those produced by the members of the chinoline series and amonc themselves. The following are the general conclusions. 2. There is a marked gradation in extent of physiological action of the members of the pyridine series of bases, btut it remains of the same kind. The lethal dose becomes reduced as w,ve rise from the lower to the higher. 2. The higher members of the pyridine series resemble in physiological action the lowver members of the chinoline series, except (i) that the former are more liable to cause death by asphyxia, and (2) that the lethal dose of the pyridines is less than one half that of the chinolines. 3. In proceeding from the lower to the higher members of the chinoline series, the physiological action changes in character, inas- much as the lower members appear to act chiefly on the sensory centres of the encephalon and the reflex centres of the cord, destroyingthe power of voluntary or reflex movement; while the higher act less on these centres, and chiefly on the motor centres, first, as irritants, causing violent convul- sions, and at length producing complete paralysis. Atthesametime, while the reflex activity of the centres in the spinal cord appear to be inactive, they may be readily roused to action by strychlnine. 4. On comparing the action of such compoundls as C9 H7 N (chinoline) with Cs H13 N (par- voline, etc.), or C8 11"1 N (collidine) w-ith C8 H'5 N (conia, from hem- lock), or C'0 H10 N2 (dipyridine) w%ith C10 Hi4 N2 (nicotine, from tobacco), it is to be observed that the physiological activity of the substance is, apart from chemical structure, greatest in those bases con- taining the larger amount of hydrogen. 5. Those artificial bases which approximate the percentage composition of natural bases are much weaker physiologically, so far as can be estimated by amount of dose, than the natural bases; but the kind of action is the same in both cases. 6. When the bases of the pyridine series are doubled by con- densation, producing dipyridine, parapicoline, etc., they not only be- come more active physiologically, but the action differs in kind from that of the simple bases, and resembles the action of natural bases or alkaloids having a similar chemical constitution. 7. All the substances examined in this researclh are remarkable for not possessing any specific paralytic action on the heart likely to cause syncope; but they destroy life either by exhaustive convulsions, or by gradual paralysis of the centres of respiration, thus causing asphyxia. 8. There is no appreci- able immediate action on the sympathetic system of nerves. There is probably a secondary action; because, after large doses, the vaso-motor centre, in common with other cerntres, becomes involved. 9. There is no difference, so far as could be discovered, between the physiological action of bases obtained f-om cinchonine and those derived from tar. Dr. McKendrick also described the physiological effects of various methyl and ethyl compounds of clhinoline. He alluded to the researches of Professor Crum Brown and Dr. Thomas R. Fraser on the action of methyl and ethyl strychnia as examples of a complete change in physio- logical action being produced by a change in chemical constitution. He and Professor Dewar had found the ethyl and methyl compounds of chinoline to have an action very different from chinoline alone. They were found to be much more active than chinoline alone, and to pro- duce effects similar to those of the higher members of the chinoline series. He then indicated the important considerations suggested by this investigation; and said it was not too much to anticipate that the chemist may yet be able to build Up compounds having effects re- sembling those of such valuable remedies as quinine, morphia, etc.- Dr. PYE- SMITII said it was gratifying to find that so important a branch of science was being investigated by two such eminent men as Dr. McKendrick and Professor Dewar. Some of the bases to which refer- ence had been made would, no doubt, prove useful medically and phy- siologically, especially in the latter capacity. With regard to cincho- nine, he had made some experiments with it on the human frame; and he was led to the conclusion that the further it was kept from pa- tients the better it would be. It was certainly cheaper than quinine, but it had many objectionable characteristics. He was glad to hear of the promised advantages of chinoline, which, if realised, would help them out of the diffiulties attendingy the administration of woorara to the mianmmalia. VACCINATION.-Mr. Thomas Taylor of Bocking, Essex, has been awarded an extra vaccination gratuity, amouniting to £'5 17s. Mr. J. Comyns Leach of Sturminster Newton has received, for the second time, a grant of £8 i6s. for efficient vaccination. ASSOCIATION INTELLIGENCE. SOUTH-EASTERN BRANCII: EAST KENT DISTRICT. TIiE next meeting of the above Branch wvill be held at the Pavilion Hotel, Folkestone, on Thursday, September i6th. I875, at 3 o'clock; Dr. HENRY LEWN-IS of Folkestone in the Chair. Dininer at 5 o'clock precisely. Charge, 6s. 6d., exclusive of xvine. Gentlemen who wish to make communicationis to the meeting are requested to inform me at once, in order that a notice thereof may be included in the circular convening the meeting. EDWARD WI-IITFELD TIIURSTON, Ziotazray Secr-ela;y. Ashford, August 29th, 1875. NORTIIERiN COUNTIES (SCOTLAND) BRANCII. THE annual meeting of this Branclh wvill be held at Elgin, on Saturday, Septemnber i 8th, at 12.30 P.MNI. Dr. VASS, of Tain, President-elect. Particulars by circular. J. W. NORtRIS MACKAY, Ilaonorai:y Secretalry and Tr-easurer-. Elgin, September 2nd, I875. SOUTHI 'MIDLAND BRANCII. TILE autumnial meeting will be held at Northampton, on Wednesday, September 22nd; HENRY TERRY, Esq , President-elect. Genitlemen intending to read papers are requested to forward their titles forthwith to Dr. Bryan. J. M. BRYAN, M.D. Honorary Secretaries. W. MOXON, Esq. 5 Northampton, September Ist, I875. MIIDLAND BRANCII. A MIEETING of the above Branch will be held at MIatlock Bath, on Thursday, September 23rd. Several papers have been promised. Further information in next week's JOURNAL. F. W. WRIGIIT, Honor-ary Secretary. Derby, September Ist, 1875. NORTII OF EN\GLAND BRANCH. THE autumnal meeting of this Branclh will be held at the Queen's Hotel, Sunderland, on Thursday, September 23rd, at 3 P.M. ; S. E. PIPER, F.R.C.S., President. The following papers have been promised. i. Dr. J. W. Eastwood. The Prevalent Practice of Advertising Me- dical Works in the Non-Aledical Press. 2. Dr. C. Gibson. Certain Forms of Blood-Diseases. Gentlemen who are desirous of reading papers will oblige by com- municating with the Secretary. Dinner at the Queen's Hotel, at 4.45 P.Hi. Tickets, exclusive of wine, seven shillings and sixpence. G. H. PHILIPSON, M.D., irhonzorary Secretary, Newcastle-upon-Tyne, September Ist, 1875. MEMTBERS PRESENT AT THE EDINBURGH MEETING. TIIE following names of members and visitors attending the meeting were entered in the book provided for that purpose in the Reception Room. The number of members of the Association who were present exceeded one thousand. Acton, Wm., Esq., London; Adams, T. R,, M.D., Croydon; Adams, WV., Esq., London; Ady, John E., Esq., Edinibuirgh; Ady, J. C., Esq., Burmah; Affleck, J. O., MI.D., Edinburgh; Agar, S. H., L.K.Q.C. V., Henley-in-Arden; Ainslie, Wm., Esq., Edinburgh Aitchison, J., Esq., Wall-end-on-Tyne; Aitken, J., MI. D., Govan; Aitken, L., MI.D., Rome; Alcock, J., Esq., Burslem; Aldred, H. A., MI.D., Lon- don - Alexander, A., Ml B., Caithtiess: Alexander, Wv., Al. D., Dundonald; Alexander, W..B., Esq., Edinbuirgh: Alford, Stephens S., Esq., London; Allan, Alexander, Esq., Jersey; Allan, D., A.D., Bionar Bridge; Allan. James, Esq., Edinburgh; Allbutt, T. Clifford, M.D., Leeds; Alsop, Thonmas 0. F., M.B., Royal Inifirmary, Edin- bulrgh; Althaus, Julius, M.D., London; Anderson, I). H. B., Al.I)., Army Medi- cal Department; Anderson, Mrs. E. Garrett, M.D., London; Andersoni, H. S., MI.D., Selkirk; Aniderson, James, A.D., Bridge of Allani; Andersoni, James, Esq., Musselburgh; Anderson, james, Esq., Ulverstone; Anderson, J. T. WV., Esq., Edin- burgh; Anderson, J. W., M1.D., Glasgow; Anderson, John, M.D., Ulverston; Andersun, Robert, MI.D., Seaton; Anderson, Thomiias, MI.B., District Asylum, Edinburgh; Anderson, T. M'Call, LI.D., Glasgow; Aninandale, Thomas, Esq., Edinburgh Andrew, Edwyn, M.D., Shrewasbiry; Andrianaly, Madagascar; Ar- buckle, Hugh W., M.D., Thorne; Archibald, D., M.D., St. Andrew's; Archibald

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Sept. 4, 1875.] THE BRITISH MEDICAL YOURNAL. 311

examined. Its action was then compared with that of the hydrochloratesof the chinoline series of bases distilling at higher temperatures, includ-ing such as lepidine, dispoline, tetrahiroline, etc. In the next place,the physiological action of the pyridine series was studied, beginningwith pyridine itself, and passing upwards to bases obtained at stillhigher boiling-points, such as picoline, lutidine, etc. Lastly, the in-vestigation was directed to the action of condensed bases, such asdipyridine, parapicoline, etc.; and the effects of these substances werecompared with those produced by the members of the chinoline seriesand amonc themselves. The following are the general conclusions.2. There is a marked gradation in extent of physiological action of themembers of the pyridine series of bases, btut it remains of the samekind. The lethal dose becomes reduced as w,ve rise from the lower tothe higher. 2. The higher members of the pyridine series resemble inphysiological action the lowver members of the chinoline series, except(i) that the former are more liable to cause death by asphyxia, and (2)that the lethal dose of the pyridines is less than one half that of thechinolines. 3. In proceeding from the lower to the higher members ofthe chinoline series, the physiological action changes in character, inas-much as the lower members appear to act chiefly on the sensory centres ofthe encephalon and the reflex centres of the cord, destroyingthe power ofvoluntary or reflex movement; while the higher act less on these centres,and chiefly on the motor centres, first, as irritants, causing violent convul-sions, and at length producing complete paralysis. Atthesametime, whilethe reflex activity of the centres in the spinal cord appear to be inactive, theymay be readily roused to action by strychlnine. 4. On comparing theaction of such compoundls as C9 H7 N (chinoline) with Cs H13 N (par-voline, etc.), or C8 11"1 N (collidine) w-ith C8 H'5 N (conia, from hem-lock), or C'0 H10 N2 (dipyridine) w%ith C10 Hi4 N2 (nicotine, fromtobacco), it is to be observed that the physiological activity of thesubstance is, apart from chemical structure, greatest in those bases con-taining the larger amount of hydrogen. 5. Those artificial bases whichapproximate the percentage composition of natural bases are muchweaker physiologically, so far as can be estimated by amount of dose,than the natural bases; but the kind of action is the same in bothcases. 6. When the bases of the pyridine series are doubled by con-densation, producing dipyridine, parapicoline, etc., they not only be-come more active physiologically, but the action differs in kind fromthat of the simple bases, and resembles the action of natural bases oralkaloids having a similar chemical constitution. 7. All the substancesexamined in this researclh are remarkable for not possessing any specificparalytic action on the heart likely to cause syncope; but they destroylife either by exhaustive convulsions, or by gradual paralysis of thecentres of respiration, thus causing asphyxia. 8. There is no appreci-able immediate action on the sympathetic system of nerves. There isprobably a secondary action; because, after large doses, the vaso-motorcentre, in common with other cerntres, becomes involved. 9. There isno difference, so far as could be discovered, between the physiologicalaction of bases obtained f-om cinchonine and those derived from tar.Dr. McKendrick also described the physiological effects of variousmethyl and ethyl compounds of clhinoline. He alluded to the researchesof Professor Crum Brown and Dr. Thomas R. Fraser on the action ofmethyl and ethyl strychnia as examples of a complete change in physio-logical action being produced by a change in chemical constitution. Heand Professor Dewar had found the ethyl and methyl compounds ofchinoline to have an action very different from chinoline alone. Theywere found to be much more active than chinoline alone, and to pro-duce effects similar to those of the higher members of the chinolineseries. He then indicated the important considerations suggested bythis investigation; and said it was not too much to anticipate that thechemist may yet be able to build Up compounds having effects re-sembling those of such valuable remedies as quinine, morphia, etc.-Dr. PYE- SMITII said it was gratifying to find that so important a branchof science was being investigated by two such eminent men as Dr.McKendrick and Professor Dewar. Some of the bases to which refer-ence had been made would, no doubt, prove useful medically and phy-siologically, especially in the latter capacity. With regard to cincho-nine, he had made some experiments with it on the human frame; andhe was led to the conclusion that the further it was kept from pa-tients the better it would be. It was certainly cheaper than quinine,but it had many objectionable characteristics. He was glad to hear ofthe promised advantages of chinoline, which, if realised, would helpthem out of the diffiulties attendingy the administration of woorara to themianmmalia.

VACCINATION.-Mr. Thomas Taylor of Bocking, Essex, has beenawarded an extra vaccination gratuity, amouniting to £'5 17s. Mr. J.Comyns Leach of Sturminster Newton has received, for the secondtime, a grant of £8 i6s. for efficient vaccination.

ASSOCIATION INTELLIGENCE.SOUTH-EASTERN BRANCII: EAST KENT DISTRICT.

TIiE next meeting of the above Branch wvill be held at the PavilionHotel, Folkestone, on Thursday, September i6th. I875, at 3 o'clock;Dr. HENRY LEWN-IS of Folkestone in the Chair.

Dininer at 5 o'clock precisely. Charge, 6s. 6d., exclusive of xvine.Gentlemen who wish to make communicationis to the meeting are

requested to inform me at once, in order that a notice thereof may beincluded in the circular convening the meeting.

EDWARD WI-IITFELD TIIURSTON, Ziotazray Secr-ela;y.Ashford, August 29th, 1875.

NORTIIERiN COUNTIES (SCOTLAND) BRANCII.THE annual meeting of this Branclh wvill be held at Elgin, on Saturday,Septemnber i8th, at 12.30 P.MNI. Dr. VASS, of Tain, President-elect.

Particulars by circular.J. W. NORtRIS MACKAY, Ilaonorai:y Secretalry and Tr-easurer-.

Elgin, September 2nd, I875.

SOUTHI 'MIDLAND BRANCII.TILE autumnial meeting will be held at Northampton, on Wednesday,September 22nd; HENRY TERRY, Esq , President-elect.

Genitlemen intending to read papers are requested to forward theirtitles forthwith to Dr. Bryan.

J. M. BRYAN, M.D. Honorary Secretaries.W. MOXON, Esq. 5

Northampton, September Ist, I875.

MIIDLAND BRANCII.A MIEETING of the above Branch will be held at MIatlock Bath, onThursday, September 23rd. Several papers have been promised.Further information in next week's JOURNAL.

F. W. WRIGIIT, Honor-ary Secretary.Derby, September Ist, 1875.

NORTII OF EN\GLAND BRANCH.THE autumnal meeting of this Branclh will be held at the Queen'sHotel, Sunderland, on Thursday, September 23rd, at 3 P.M. ; S. E.PIPER, F.R.C.S., President.The following papers have been promised.i. Dr. J. W. Eastwood. The Prevalent Practice of Advertising Me-

dical Works in the Non-Aledical Press.2. Dr. C. Gibson. Certain Forms of Blood-Diseases.Gentlemen who are desirous of reading papers will oblige by com-

municating with the Secretary.Dinner at the Queen's Hotel, at 4.45 P.Hi. Tickets, exclusive of

wine, seven shillings and sixpence.G. H. PHILIPSON, M.D., irhonzorary Secretary,

Newcastle-upon-Tyne, September Ist, 1875.

MEMTBERS PRESENT AT THE EDINBURGH MEETING.TIIE following names of members and visitors attending the meetingwere entered in the book provided for that purpose in the ReceptionRoom. The number of members of the Association who were presentexceeded one thousand.

Acton, Wm., Esq., London; Adams, T. R,, M.D., Croydon; Adams, WV., Esq.,London; Ady, John E., Esq., Edinibuirgh; Ady, J. C., Esq., Burmah; Affleck, J.O., MI.D., Edinburgh; Agar, S. H., L.K.Q.C. V., Henley-in-Arden; Ainslie, Wm.,Esq., Edinburgh Aitchison, J., Esq., Wall-end-on-Tyne; Aitken, J., MI. D., Govan;Aitken, L., MI.D., Rome; Alcock, J., Esq., Burslem; Aldred, H. A., MI.D., Lon-don - Alexander, A., Ml B., Caithtiess: Alexander, Wv., Al. D., Dundonald; Alexander,W..B., Esq., Edinbuirgh: Alford, Stephens S., Esq., London; Allan, Alexander, Esq.,Jersey; Allan, D., A.D., Bionar Bridge; Allan. James, Esq., Edinburgh; Allbutt,T. Clifford, M.D., Leeds; Alsop, Thonmas 0. F., M.B., Royal Inifirmary, Edin-bulrgh; Althaus, Julius, M.D., London; Anderson, I). H. B., Al.I)., Army Medi-cal Department; Anderson, Mrs. E. Garrett, M.D., London; Andersoni, H. S.,MI.D., Selkirk; Aniderson, James, A.D., Bridge of Allani; Andersoni, James, Esq.,Musselburgh; Anderson, james, Esq., Ulverstone; Anderson, J. T. WV., Esq., Edin-burgh; Anderson, J. W., M1.D., Glasgow; Anderson, John, M.D., Ulverston;Andersun, Robert, MI.D., Seaton; Anderson, Thomiias, MI.B., District Asylum,Edinburgh; Anderson, T. M'Call, LI.D., Glasgow; Aninandale, Thomas, Esq.,Edinburgh Andrew, Edwyn, M.D., Shrewasbiry; Andrianaly, Madagascar; Ar-buckle, Hugh W., M.D., Thorne; Archibald, D., M.D., St. Andrew's; Archibald

312

John, M.B., Biggar; Arlidge, J. T., NI.D., Newcastle-under-Lyme; Arras, William,ogsq., Wetheral; Arrott, George, Esq., Lockerbie; Arthtir, Hutgh, NI.D., Airdrie ;

Atwell, G. Haines, Esq., Altrincham; Atthill, Lombe, M.D., Dublin; Atkinson,E. T., Esq., Richmond; Atkinson, George P., Esq., Pontefract.Baildon, H. C., Esq., Edinburgh; Baird, G. Dallas, Esq., Linlithgow; Ba'-er,

Alfred, Esq., Birmingham; Baker, James, Fsq., Scarborotigh; BaLker, J. C., M.D.,Liverpool; Baker, J. Wright, Esq., Derby ; Balfoinr, A. II., Esq., Portobello; 1'al-four, A., M.B., Portobello; Balforur, J. H., I.D., F.R.S., Edisbhirghi; Balfour,Thomas A. G., NI.D., Edinburgh; Ball, Alfred, Esq., York; Balhantyne, Alexan-der, NI.D., Dalkeith; Banks, Alexander, Esq., Edinburgh; Harbour, George F.,Esq., Bonskeid; Barety, A., Nice; 13arnes, Arthur R., Esq., Favcrsham; Barnes,Henry, M.D., Carlisle; Barnes, Robert, I.D., London; Bartlett, H. Critchett,Esq., London; Barr, Thomas, NI.D., Glasgow; Bassett, John, M.D., Birmingham;Batten, Thomas, Esq., Coleford; Baxter, W., Esq., Kilmarnock; Beatson, GeorgeT., M.B., Nenvcastle-on-Tyne; Beddoe, John, M.D., F.R.S., Bristol; Bedford, H.C., Esg.. Cape of Good Hope; Begbie, J. Warburton, M.D., Edinbturgh; Begley,W. C., M.D., London; Belcombe. Rev. Francis E., Edinburgh; Bell, Rev. D.,M.D., Goole; Bell, James N., N.D., Kettle; Bell, J. H., I.D., Bradford; 1ell,Joseph, Esq., Edinburgh; Bell, Robert, I.D., Glasgowv; Berinett, E. A., Esq.,Nelson-in-Marsden; Bennett, E. H., AI.D., Dublin; Benneat, H. N., Esq., Dub-lin; Bennett, J. Htughes, NI.D., F.R.S.E., FdinLurgh; Bennett, J. AN., Esq., ANilleCrux House; Bennie, Jas., Esq., Currie; Bernard, Walter, L.K.Q.C.P., London-derry ; Beveridge, Robert, I.B., Aberdeen; 13erne, J. F de, Esq., Paris; Berne,J. F., Esq., Alauritius; Bilton, Lewis, Esq., Edinsburrgh; Birndon, XV. J. Vereker,Esq., Edinnbunrgh; Bishop, John, M.D., Edinsburgh-; Bishop, 'thomas, Al D., Paris;Blair, Sheriff, Inverness; Blandford, Jos. W., Esq., Durham; Blanshard, Geo.,Esq., Edinburgh ; Blair, Wm., M.D., Jedburgh; Il3aney, Roland, Esq., India;Bleloch, A., M.B., Edinburgh; Block, Oscar, Copenhagen; Blltuett. John, Esq.,Chesterfield; Blumer, Luke, NI.D., Sunderland ; Ilodington, G. F., M.D., Kings-winford; Borthwick, Alexander, NI.D., Dlumfries; Bott, John, Esq., Huddersfitld-Bott, Thos. B., NI.D., BtHry; Botichet, Gtorges, Esq., Nlaurituius; Bosses, Richard,Esq., Richmond, York; Bowvie, John, Elq., Edinburgh; B3radley, Charles, Psq.,Nottingham; Braidwood, P. NI., IBD., Birkenhead ; Brakeniridge, Danid, IBD.,Edinburgh; Branlwell, B., M.IB., Newicastle-ori-Tyne; Bramss-ell, J. XV., Esq., NorrlIShields; Bramwell, J. P., M.N., Perth; Branford, XV. H., Esq., Edinbulrgh Brat-ton, James, Esq., Shrewsbury; B3remner, Bruce A., NIB.D., Edinburgh; Bremner,Allan S., Esq., Edinburgh; Bridger, John, Esq., Cottenhasii; Briclgnian, I. T.Esq., Berkeley; Briggs, I-Henry, NID., Burnley; Britton, lhonoas, NI.D., Halifax;Broadbent, Lewis G., IBD., Hamburgh; Broadbent, S. W., Esq., Souith Hetton;Durham; Broadbent, W. H., NI.D., London; Brodie, David, M.D., LilecntonBrooke, Sir William, Nice and London; Brooks, James W., NI.D., New York;Bronherston, Peter, Esq., Alloa; Brown, Alexander, Esq., Coldstreamn; Brown,Alexander Crtrm, I.D., Edinburgh; Brown, Colville, IB.D., Berwick-on-Tweed; Brown, Henry, Esq., Northallerton; Brown, James, Esq., Isle of Skye ;

Brown, Joseph J., M.B., EdinbuLrgh; Browvn, Robert, NI.D., Tranent- Brown, T.Sinclair, M.B., Barbadoes; Brown, XVm.. Esq., Carlisle; Browne, Lennox, Esq.,London; Bruce, Robert, NI.D., Edinburgh; Bruce, XVm., I.D., Diisgwall; Bruce,W. T., Esq., Halifax, Nova Scotia; Brumell, Matthew. Esq., Morpetls; Brusnton,T. Lauder, NI.D., F.R.S., London; Bryson, Jas NI., Esq., Edinburgh; Blrchan,Alex., Esq., Ediniburgh; Buchanan, A. E.D., Glasgow; Buchanan, Andrewv,M.D., Glasgow; Burchanan, George, I.D.. Glasgow; Hrullhus, XVm., I-sq., Staf-fordshire; Burn, John, Nt.D., Edinburgh; Buirns, John J. D., M.D., Rochester;Burrows, Sir Corcly, Brighton Butler, Thomas NI., Esq., Guildford.

Cadell, Francis, NIB., Edinburgh; Cadell, Major T., Cockenzie Houise; Cald-well, John, Esq., Shotts; Cameron, Hector C., i.D., Glasgonv; Cameron, Jchn,M.B., Lochgilphead; Cameron, R. M., Esq., Edinburrgh; Campbell, J., Esq., Dun-dee; Campbell, J. A., Esq., Garland Campbell, Peter, NLD., Edinburgh; Camp-bell, Wm., Esq., Hastings; Campbell, Wm., Esq., Lonidon; Campbell, Wm. Wat-son, M.D., D)unse; Candy, John, NI.D., Devonport; Cappie, James, M.D., Edin-burgh; Carey, Ernest Gilbert, Esq., India; Carey, Wm., Esq., EdiiibLrrgh; Car-lyle, XV. J., NI.B Langholm; Carmichael, J., Esq., Edinbturgh; Carmichael, Jas.,M.D., Edinburgh; Carmichael, Vrn., Esq., Edinburgh; Carmichael, XV. S., E.l).,Edinburgh; Carmichael, W. M., Esq., Australia; Carnegie, John, NID., Chester-field; Carpenter, Alfred, IBD., Croydon; Carphin, J. R., Esq., Edinburgh ; Car-ruthers, J. B., I.D., Edinburgh; Canter, '. A., I.D., Leaminigton; Cash, A. NI.,

M.B., Edinburgh; Cassells, J. P., M.D., Glasgowv; Cathcart, Charles W., Esq.,Edinburgh; Caton, Richard, I.D., Liverpool; Caverhill. T., osq., Haddington;Chadnvick, Charles, NI.D., Leeds; Chalmers, Short, Lsq., Edinburgh; Cham-bers, Thomas, Al.R.C. P., London; Chlampney, C. Ihornston, Etq., Glasgowv; Cham-pionniere, M.D., Paris; Chapman, J., Esq., Edinburrgh; Charles, J. J., N.I.,

Belfast; Charlesworth, James, EsL., Hanlev; Chlarteris, NI., NI.D, Glasgowv;Chavoin, Silmours, Esq., Edinburrgh; Cheyne, W. Watson, NI. B., Shretland ; Chiene,John, Esq., Edinburgh; Chisholm, XVm., Esq., Edinbturgli; Christie, lhomas B.,M.D., Ealing; Christison, Sir Robt., Bt., Nh.)., D.C.L., Edinburgh; Church, H.M., M.D., Edinburgh; Churcb, W. J., Esq., XWeymotitlh; Clark, Andrew, A.D.,London; Clark, Janses, NBD., Chasetons-; Clark, Robt., Esq., Edinburrh: Clarke,V. C., M.D., London; Clarke, W. NI., Esq., Bristol; Clouston, T. S., I.D., Ed-inburgh; Clunre, J. Leopold, Esq., Jamaica; Coats, Joseph, N.I., Glasgows;Cochran, John, NID., Edinbrurgh; Cocki-oft, Wm., Esq., ANicldleharn; Coghill, J.G. Sinclair, NB.D., Edinbrrrgh; Coldstreanm, John, Esq., Edilnburgh; Colston, Jas.Esq., Edinburgh; Constable, John, I.D., Leicbhars; Cooke, XV. H., IBD., Al-dridge, Walsall ; Coombs, Rowvland H., Esq., Bedford ; Cooper, Jas., I-sq., Cro-mer; Cooper, W. J., Esq, Richmord, Surrrey; Copeman, E., NI.D., Norwich:Corbin, M. A. B., Esq., Guernsey; Courmack, Sir John Rose, I.D., Paris; Corn-wall, James, Esq., Fairford; Cossar, 'Ihonsas,NI.D., King's Lynn; Cotton, H. J.,M.B., Edinburgh; Cotirtenay, G. T., E'q., 1'ranent; Coveney, James H Esq.,Prestwichl; Cowair, Fred. S., Esq., Bath; Cossan, Faminel, Esq., Bath: (onsell,George, Esq., London; Cox, Charles, Esq., Penicuik; Cox, John D., F'sq.,Innerleitben; Cox, Joshua J., EsqF, Innerleithen Coxe, Sir James, A1.D., Kiriel-Ian; Crabb, James, NIB., Ediisbtirgh ; Craig, Archibald, N.B., Pathbead- 'ord;Craig, W., AE.D., FdinbuLrgh; Crawford, D., Esq., Aberdouir; Crasford, R., Esq.,London Crease, James R., Esq., fonith Shields; Cress,ncell, Pearson R., Esq.,Donvlais; Crichton, Geo'ge, NI. B., Perth; Crichton, James S.. N.D., Arbroath,Crickmay, Edsard, EsL., Laofield; Ciighton, R. W., NI. t)., Tavistock; Cripps,Ednsard, EFq., Cireccester; Cripps, Edssard C., EIsq, Cirencester; Cioom, J. Hal-hiday, N.B., Fdinnibunrgh; Cullhing-vorth, Cbhales J., Fsg., NManchestcr; C(imming,Wm., IBD., Edinbtrrgh; Curmnning, James, N.I., Edinbir-gh; Cr.siiughamn,NMurray, Esq., Glasgow-; Ctunningham, 1). J., AI.B., Ediriburrgh; Cunynghame, R.J. B., M.D., Edinburgh; Currrie, John, M.D., Lydney; Cntlribert, Clarkson, NI.D.,Edinbuurgh; Cutbbertson, David, I.D., Denny; Cutrhill, James, NI.B., Denny.Daldy, T. NI., IBD., London; Dalgleish, W. Scott, Esq., Edinburgh; Darnly,

[Sept. 4, 1875.

Clement, Fsq., Alauritius; Davidscn, Alexander Dyce, M.D., Aberdeen; Davies,Andrew, Esq., Swansea; Davies, David, Esq., St. Andrew's; Davies, Ebenezer, Esq.,Swansea; Davies,.lohn, M.D., Maesteg; Davies, RoLert, &sq., Abergele; Davies-Colley, T., M.D., Chester; Davis, E., Esq., Cymer; Davis, ]H. L., Esq., W\ales;Davis, R. A., XI.D., Lichfield; Dawson, Adam, Esu., Edinburgh; Day, W. H.,Ml.D., Londoin; Deas, Peter Iltaury, Ml.B., M1accle'ficld ; Deigliton, Christt pher,M.D., Clapham; Denham, J. S., M.D., South Shields; Denton, E. R., Esq., Lei-cester; Desmond L. E., M.D., Liverpool; DeNuar, Alexander, A.D., NMelrose;Dewar, James A., M.D., Arbroath; Dick, john, Esq., Edinburgh; Dickson, Alex.,MI.D.. Glasgow; Dickson, Rev. T. Miller, Clauigliton; Dickson, Walter, AM.D.. Lon-don ; Dickson, Wm. James, M.D., Falkland Dix, John1, Esq., Huhll; Dolman. A.H., Esq., Derby; Douigall, Joseph, Esq.. Edinburh ; Douglas, Captain C., Edin-burgh: lDotuglas, Henry, M.D., Duinfermline; Douglas, Mordey, Esq., Stunder-land; Douglas, R. Green, Esq., Edinbtirgh; Dow, Wm. B., M.D., Dunferm-line; D.vwnie, R. Ml., MI.D., Bengal, India; Downie, ihomas, M.D., Blantyre;Dos se, Tlhomas S., M.D., London; Dr-ew, John, M.B., Stirling; Drrimmond, Fd-wvard, AM.D., Royton; Drysdale, John, MB., UJphall; Duinbar, Henry, M.D.,Kirkmaiden; Duincan, Alexander George, M.B., Crimond; Durcair, A. Jas., M.D.,Dundee; Duncain, J. Matthews, M.D., Edinburgh; Duincan, John, M.D., Edin-burgh; Duncanson, J. J. Kirk, M.D., Edinbturgh; Dunlhp, John, M.D., Edin-burgh; Dcinn, Robert, Esq., London; Dunsmtire, James, MI.D., Edinburgh; Duns-mure, James, jun., M.I)., Edinbtirgh; Dupiy, M1. E., Paris; Dturand, Ruidolphe,Esq., Alauritius; Durham, James, Esq., J.P., Mayfield; Duirraiut, Christopher M.,M1.D., Ipswich.Eagles, Woodfield, Eso., Aylesbury; Eanmes, J. A!ex., M.D., Cork; Eames, J.

C., MB.B., Manchester; Eassie, Wmi., Esq., Lonidon; Elliott, Robeit. M.D., Car-lisle; Elliston, W. A., M.D., ipswich Evans, Charles, Esq., l-,akewell; Evans,Johni, M.D., Stinderland ; Evans, I lios. I). F., MI.B., Edinbutrgh; Eva-nrs, Thomas,.LD., Nesrquay; Everett, D., Esq., Worcester; Ewart, T. C., Esq., ILondcmn.Faircloth, Richard, Fsq., Nesmarket; Fairless, W. D., M.D., Bothwsell; Fal-

coner, R. Wilbraham, MI.D., Bath; Farquharsoni, John, Esq., Stockton-on- ces:Farquhatson, Robert, MX.D., Lortdon: Fassen, C. H,, Esq., Edinburgh; Favell,Wm. F., Esq , Sheffield ; Fergrus, Ansdrewv, i.D., GI.;sgows F;er-gusonr, F., EsqBolton ; F erguison, John, Esq., Edril u.rghi ; Fergussor, Sir William,t Pait.,London; Field, George, Esq., Lond. ii; Fidlay, WNri., M.D., Edinibulgh; Finlay,W. A., M.D., Edinbitrgh; Finlayson, Jas., M.D., Glasgo' Finla)son, M., Esq.,Leith; Finlay-son, 3homas, ELsq., Leith; Finzi, J. NI., Esq., Icndon Fisher, S.Winter, M.D., London; Fleniing,.Andrew, Esq., EdinbUtrgh; Fleming, 3. N., M.D.,Newcastle-on-Tyive; FklITling, Wit. Jas., M.B., Glasgon; Fletcher. Adam, M.D.,lBury; Fletcher, Bell, M.D., Birmingham; Flctcher,J. ihepleid, M.D., Mlanches-ter; Folker. W. H., Esq., Hanley ; Fo!sots, Charles F., Esq., Boston, IT.S.; Forbes,D. Ml., Esq., London; Forbes, Walter, M.D., Edinburgh; Foster, Balthazar, MJ.D.,irmingham; Fothergill, J. M\ilner, M.D., London; Fothergill, J. R., M.D., Dar-

lington; Fotulis, Jas., M.D., Ed ibutrgh; Frowler, W. C., L.D., Edinbrrrgh; Fox,Charles Henry, M.D., Brislington, Bristol ; Fox, Cornelius, I.D., Chelmsford;Fox, Edwvard L., Ml.D., Cliftcn; Frain, Joseph, M.D., Sotith Shields; Fraser,Donald, MI.D., Paisley; Fraser, John, Esq., Edinburgh; Fraser, Roderick, Esq.,Edinburgh; Fraser, Thomas, Esq., Arbroath ; Fraser, T. R., M.D. Knurtsford;Freer, Alfred, E'q., Stourbridge; Ft cer, Frederick A., Erq., Govan; Frew, Wm.,M.B., Newmilns; Fry, Charles D., MI.D., Ferbane, Ireland ; Furley, R. C., Esq.,Editiburgh; Furley, W. Grant, Esq., Fdiiiburgh.

Gairdrier, MI. B., MI.D., Crteff; Gait-dner, XV. T., MI.D., Glasgow; Galt, John,Esq., Ashton-under-Lyne ; Garland, (.)nm nd H., N.B., Leith; Garman, J. C.,Esq., Wednesbtiry ; Garner, J., Esq., lirmingham; Garner, John E., Esq., Pres-ton ; Garfhside, James, Esq., Liverpool: Gentle, David, EFq., British Honduiras;Grbb, C. J., Ml.D., Newcastle-on-Tynle; Gibbons, R. A., AM. K., Edinburgh; Gib-son, Charles, M.D., Nctwcastle-on-Tyne Gibson, Charles Henry, Esq., laventry;Gill, H. Clifford, Esq., York; Gillespie, James D., AL.D., Ediniburtgh; Gilruth, G.R., Esq., Edinburgh; Girvan, Robert, Esq., Mlaybole; Glendinning, Geo., Esq.,Edinburgh Royal Jnfirmary: Goldie, George, Esq., Leeds; Goldie, R. W., Esq.,London; Goodall, P., Esq., lBrminghlam; Goodchild, John A., Esq., Ealing;Goodeve, K. C., Esq., Bristol; Gordon, D.. MI.D., Edinbrlrgh; Gordon, H.,ALB.,Kirkcaldy; Gordon, J., IB., East Linton; Gordon, P., Esq., Edinburgh; Gordon,XV., A.D.. Edinbtirgh; Gorman, J., Fsq., Rtitherglen; Gornall, J. H., Esq., WXar-rington; Graham, A. F., iI.D., Liverpool; Graham, B., NIP., I o-ness; Graham,J., Esq., London; Grainger, J. R., Esq., Kilniarnock; Grange, W. D'Oyly, MB.,Edinbtirgh; Grant, David, Esq., Edinbrirgh; Grant, Jas., AI., Longton; Grant,Rev. Jitres, Edinburgh; Grant, John, Esq., Penicuik Grassett, Frecerick L. Nt.,

Esq_, Edinbturgh; Granely, Richard, Esq., Newick: Gray, James, MI.D., Glas-gonv; Gray, Thos., Esq., Duimfries; Greathead, John B., Esq., Editibtirgh; Green,Ed. F. S., Glasgow; Gregory, George, NID.. Bolton; Greig, David, Esq.,Edinbulrgh; Grierson, S., Esq., \1elrose; Griffiths, T. D., NI.D., Sf ansea ; Grigor,John, AM.D., Rome Groesbeck, Herman J., NI.D., Cincitinati, Ohio; Grosvenor,XVm., Esq., Londlon; Groves, Charles I-H., M.i., Edirbuirgh; Guieneati de NMussy,Noel, I.D., Paris; Gunn, RZ. Nlarcus, AN.B., Gohsp:c Gunnr, Wm., Esq., Edin-birrgh; Gtithrie, David K., Esq., Liberton ; Gyergyai, Arpad, NI.D., Klausenburg,Huingary.Habershon, S. O., NID., London; Hadden, John, AN.D., Horncastle; Haddon,

John, NI.D., Nianchester; Hadfield, James, Esq., Honwdon-on-Tyne*; Hairiiing,William, NI.D., Chester; Haldan, Bernlard, Esq., Preston; Hall, C. Radclyffe,NI B., Torqtiay; H-iall, J. G., Esq., S-wansea; Hall, J. Lewis, Fsq., Ehdinbtirgh;Ball, XVWlllam, Esq, Salford; laltie, Alexander G., Fsq., Antigua; Haniilton,Alexander, Esq Ashton-on-Lyrre; Hamilton, Archibald, NI.D., indermere;Hamilton, David J., Esq., Edinburgh; Hanmilton, HtLibert, Esq., Edinbtirgh; 1lam-ilton, Ihomas, AN.D., Kelso Bardcsti, J. J., Esq., Galashiels; Hardie, James,NIl.)., NManchester; Hardie, J. R., NlI.B., Ediribuurgh; ar ker, Ihonias, NI.B.Yorkshire; Harrinson, Isaac, Esq , Reading; Harris, Alexarnder, Fsq., Edinburrgh-Harris, Henry, .ID., Recldruth Harrison, A. J , NI. us., Walsall; ]Hart, Adolphus,Esq., London; IHart, Ernest, Esq.. London; Harvey, Alcxaridet, NIT)., Aberdecn;Har ey, Alexander, jinn., Esq., China; Harney, Charles A. NI.D.. Cork; Hawvard,Edwsin, NI.D., London; Hn kins, Clemtnct, F.sq., Cheltenshsanm; Haynard, James,Esq., London; Heath, Cbristopher, Esq., I oridon; Heaton, J. D., M.D., Leeds;Heffernan, Edward, Esq., Spenn3 moor; Hemming, J. HBighes, Esq., Kimbolton.Hesmning, XV. B., Esq., London; Hendlerson, Alexander, , IJartclk, GlasgosvHenry, Alexansder, NI.B., Londcn Honsley, HInry, NIl)., lath;; HIepbtirn,Danid, Esq., Edinburgh ; Fepper, C.sptairi, Edirrbuirgh; Herl ertson, Richard G.,Esq., Climnock, Ayrshire; 1lull, Charles, NI.D., Lierrpool;, 111,Nl,attheNsv, Esq.Bootle, Liverpool; Ilingstous, J. R , Esq., Clifton, Yoi-k; Hir-clffeld, John C.,

I.B., Bariff; Hoare, WVm. P., Esq., Dartford; Hoggan, Georgei, A.D., London.Ho,gan, Frances Elizabeth, NI.D., London; Holdsworth, Sanstel, AN.D., Wakefield; Holland, E., I.D., London; Holmes, James, NIB., Eerwick; Home, A

THE BRITISH MEDICAL _OURNAL. I . -

THE BRITISH MEDICAL _OURNAL.S. Henry, Esq, Edinburgh;' Hooper, W. D., M.D.. Lynchburg, U.S.; Hopgood,Thomas F., Esq., Sunderland; Houston, Patrick C., M.D., Kirkcaldy; Hovell,D. De Berdt, Esq., Clapton, London; Howat, Rev. H. T., Liverpool; Hilme,George H., NLD., Newcastle-on-Tyne; Humphreys, J. R., Esq., Shrcwsbliry;Hunt, W. A., Esq., Yeovil; Hunter, Alexander, Esq., Edinburgh; Hulnter, George,M.D., Linlithgow; Hunter, Thomas, Esq., Amoy, China; HBunter, William B.,M.D., Jedbiirgh; Hunter, XV. M., M.D., Eckington; Huntley, Robert E., M.D.,Jarross on-Tyne; Huisband, W. D., Esq., York; Huitchison, J. C., Nl.D., America.

Imlach, Francis, NI.B., Liverpool ; Imlach, Francis 1'., Fsq., Edinbturgh; Inglis,Archibald, NI.D., Ediiuburgh; Irvine, NI. S., Esq., Edinburgh; Irvine, WV. Stewart,AI.D., Pitlocbiy.

Jackson, J., Esq., Birmingham; Jackson, J., Esq, Bradford; Jackson, J. B.,Esq., Birmingham; Jackson, R. A., Esq., Lancaster; Jagielski, V. A., NI.D., Lon-

don; James, Alexander, NI\B., Liverpool; Jamieson, James, Esq., Edilbuirgh;Jansz, Stephen P., Esq., Ceyloni; Jeaffre.son, C. S., Esq., Nesscastle on-Tyne;Jefferiss, Robert R., Esq., Dalkeith Jefferson, T. J., Esq.. Nlarket Weighton;Jeffreys, Richard, Esq., Clhesterfield; Jepson, Edsward, Esq., Durham; Jepson, J.,Esq., Durhamn; Johnson, Christopher, Esq., I ancaster; Johnson, john, Esq.. Lon-don; Johnson, Z., L.K.Q.C.P., Kilkenny; Johbiston, James, NI.B., Birmingham;Johnston, R. C., Esq., Edinbtirgh; Johnston, Rev. W., Vienna; Johnston, Wil-liam, NI.D., Stirling; Johnustone, John. Esq., Birmingham; Jolly, Robert, MI D.,Birmingham; Jones, A. E., NI.B., Edinburgh; Jotues, Esvan, Esq., Aberdare;Jones, P. S., M.D., Sydney; Jones, Talfotird, NIB., Brecon; Jones, T. Wharton,E!zq.. F.R.S., London; Jones, William, Esq., Ruabon; Jordani, Ftirneaux, Esq.,Birmingham.

Kealy, J. R., NI.D., Gosport; Keetley, T'homas B., Esq., Grimsby; Keiller,Alexander, N.D., Edinbturgh; Keith, George, Esq., Fdinbturgh; Keith, Thomas,NI.D., Edinbutreh; Kemp, W. E., Esq., Castleford; Kennedy, John, NI.D.. Elie;Kennedy, R., Esq., Edinbuirgh; Kennedy, R., NI.D., London; Kennedy, J.,M.D.. Dalkeith; Kerr, William D., Esq., Edinburgh; Kersluaw, John, Esq,, Roy-ton; Kerswvill, Robert, Fsq , St. Germains; Key, A. Cooper, Esq., London; King,Kelburne, Nl D., Huill; Kirk, J. Balfotir, MI.D., Bathgate; Kirk, Robert, NI.D.,Glasgowv; Kirkwvood, James, Fsq., Edinburgh; Knox, John, NID., Bakewell;Knox, Thomas, Esq., Edinbturgh.

Laidlawv, R., Esq., Glasgosv; Laing, George, Esq., Ferryport-on-Craig; Laing,James, NI.D., Bridge-of Earn; Lane, W. IL., NIB., Crossgates, Duunfermline;Latimer, H. A., Esq., Swanisea: Lawrence, J., NI.D., Ctimnock; Lassson, W. C.,Esq., Armagli; Leak, F. NI., Esq., Hemsworth; Leak. T. NI., Esq, Hemsnorth;Lee, Edmtund, Esq, Alanchester; Leech, D. J., AN.B., Nlainchester; Leeming,Robert T., Esq., Kendal; Legat, Andrew. NI.D., Sonuth Shields; Leitch, J. NI.,Esq., Edinburgh; Leitch, Robert, Esq., Edinburgh; Tleslie, Lotius. NID., Alton,Hants; Lewis, David, Esq., Edinburgh; Lewis, Thomas, NI D., Thornhill,Llanelly; Liddle, John, Esq., London; Liebman, NI. Charles. Trieste; Liebreich.R., Esq., London; Liitdsay, Johi,, NID.. Lesmahagowv; Lindsay. J. Muturray,N.D., Derby; Iindsay, Robert, Esq., Clovenfords; Lindsay, Wm. Lauider, NI. D.,Perth; Lintoua, John, AT. D., Edinburgh ; Lister, Joseph, Esq., F. R. S. S , din-burgh; Lithgow, S. A., Esq., Edinburgh; Little. W. J., NI.D., London; Little-john, Henry D., M.D., Edinbtirgh; Livesay, WVilliam, I.D., Sudbliry; Livy,John, M.D., Bolton; Lockie, S., NI.D., Carlible; Locking, J. A., Esq., Hiill;Lodge, Ll., Esq, St. Asaph; Login, Thomas, I.D., Penpont, Dtimfriesshire;Logie, James S. S., AI.D., Kirkwall; Longbotham, George, Esq., Nliddlesborough;Longmuir, James, NM.D, Bathgate; Lord, Charles F. J., Esq., Hampstead;Lorimer, George, NI.D., Buxton; Lothian, John A., NID., Glasgosw; Low. RobertBruce, NLD., Helmsley; Lowe, George, Esq., Buirton-on-'rent; Lowe, John,Esq., Edinburgh; Lowe, WV. G., NI. B., Btirton-on-Trent, Lowe, W. H., \I. D.,Edinburgh; Lowne, Thompson, AT.D., Edinburgh; Lowther, Richard, NI.D.,Cartmel; Lucas, Robert, I.D., Dalkeith; Lucas, Thomas P., Escf., London;Lund, Edward, Esq., Manchester; Lyall, Andrew, Esq., Leven; Lynes, Edward,I.D., Coventry; Lyon, James G., NI.D., Glasgow; Lyster, C. E., I.D.. Liver-

pool.NI'Alister, James, Esq., Kilmarnock; NI'Bain, Himgh, Esq., North Berwick;

M'Bain, James, M.D., Edinburgh; NIC'allum, Ed., Esq., Edinburgh; NI'Carron,John, Esq., Glasgow; NI'Casgie, J. G., Esq., Berwick; N'Cheane, William, Esq.,Liverpool; NI'Clelland, 13. Brown, NI.D., Banbridge, Ireland; NI Clintock, A. H.,M.D., Dublin; NI'Clure, Thomas, Esq., Bath; NI'Coll, Hector, Esq., Tobermory;M'Culloch, S. H., Esq., Australia; MI Diarmid, John, NI.B., Nlurthly; Macdonald,Angus, M.D., Edinburgh; Nlacdonald, George, Esq., Nlarkinch; Macdonald, J.Alex., M. D., Woburn; NI'Donald, K. N., Esq., Ratho;N*acdonald, William,Esq., Maryhill, Glasgow; NMacdonald, W., I.B., Inverness; NMacdonald, William,Esq., Edinburgh; M'Dougall, James N., M.N., ColdinEham; NI'Dowall, J. G.,M.B., Sheffield; Nlacdowall, E. XV., I.D., Nlorpeth; NlacEwan, David, M.B.,Dundee; N'Ewen, William, NIBD., Chester; I'Fadyen, D., M.D., Stirling;Macfie, H. NI., Esq., Edinburgh; NMacgregor. D., Esq., Penrith; Mlacgregor,John, IBD., Liverpool; Ai'Intyre, J., I.D.. Odiham; NI'Intosh, Villiam C.,M.D., Nlurthly; Nlackay, Alexander, NI.D., Crook, Dtirham; Nlackay, Duncan,M.D., Inverness; Nlackay, John, Esq., Edinburgh; Mackay, J. W. Norris, I.D.,Elgin; NMackay, Villiam P., NI.D., Hull; Alackeith, D., Esq, Glasgow; M'Ken-drick, John G., I.D., Edinburgh; Nlackenzie, A. R., NI.D., Fortrose; NIac-kenzie, James, Esq., Edinburgh; Nlackenzie, Morell, AN.D., London; Nlackenzie,WX. M., M.D., Kelso; Nlackie, James, Esq., Darlington; Mackinnon, John, Fsq.,Ardrishaig; Nlackintosh, Angus, NI.D., Chesterfield; Alacknight, A. E., Esq.,Edinburgh; Nlaclachlan, Duncan, Esq., Edinbturgh; NI'Lachlan, Samuiel F., Esq.,Moffat; Nlaclagan, J. NI., NI.D., Riding-NMill-on-Tyne; Alaclagan, T. J., IBD.,Dundee: N'I,aren, Adam, Esq., Edinburgh; M'Laren, David, Esq., Edinbturgh;Alaclaren, James, Esq., NMorningside, Edinburgh; NIl aren, James B., M.D.,Glasgosv; M'Laren, M., Esq., Johnstone; Maclaren, P. H., NI.D., Lasswvade;Nlaclaren, Roderick, M.D., Carlisle; NI'Latmchlan, Alexander, Esq., Tobermory;NI'Lean, Allan, NI.B., Portland; Nlaclean, Edward, Esq.. Nlanchester; Nlaclean,John, Esq., Ediuubturcgh; NI'Lean, Nlalcolm, LDI., Carbost ; NILeod, Donald,M.D., Kilmarnock; Nlacleod, George H. B., NID., Glasgow; NI'Leod, John B.,M.D., Galston; Macnab, Finlay, Esq., Hull; Nlacnab, James, Esq.. Stirling;NIcNab, John, NI.D., Loch Inver; Alacnair, R., NI.D., l.eith; NTacnamara, C.,M.D., Calcutta; N'Naught, James, Esq., Ravenshall; NI'Naught, Thomas, Esq.,Dumfries; M'Neil, William, M.D., Stranraer; Nlacpherson, P., M.D., London;NI'Rae, Alexander E., I.D., Penicuik; Nlacswiney, S. NI., AI.D., Dublin;MIacWatt, R. C., NI.D., Dumnse; Nlanby, A. R., Esq., East Reedham; Marcet,

William, AID., F.R.S., London; Nlarshall, Henry, AID., Bristol; Nlarshall, XV.

J., NI.D., Greenock; Nlartin, Alfred H., NI.B., Carmarthen; NMartin, R. J., Esq.,Atherton, Manchester; NMartin, William Y., Esq., Walkden, Bolton; Martyn, S.,M.D., Clifton;NMason, Frederick, Esq., Bath; Nlassey, I., I.D., Nottinghanm-Nlasson, Donald T., I.D., Edinburgh; Nlasterton, John, I.B., Devizes; Nlather,

George R., M.D., Glasgow; Matthias, Alfred, Esq., Bridgenorh; Matthew,

Alexander, Esq., Kinross; Maxwell, Charles M., Esq,. London; May, Joseph,

Esq., Rathfriland; Alayo, Alfred C., Esq, Mlildenhall; Meacham. Edsi%rd, Esq.,

Manchester; Meade, R. H., Esq., Bradford; Mtarns, John Herbert, Ese, Shef-

field; Meikle, John, Esq , Melrose; Mellis, James, Esq., Prestonpans; AlMizies,William, \1. D., Edinburgh; Meredith, John, \I.D., Wellington, Somerset; Mexeer,John C., M.D., Royal Navy; MIeteyard, C. J., Esq., Clunbury; Aliddleton, James,

M.D., Edinbturgh; Mliddleton, John, Esq., Edinbuirgh; Miles, A. J., Cincinnati,

Ohio; Millar, James, M.D., Glasgow; Mdllar, John, Esq., Newmains; Mliller,Alexander Gordon, IM1.D., Edinbturgh; Miller, P., Esq., Edirnburgh; Mliller,William, MI.D., Eye; Alilligan, John S., M.D., Thornhill; Milne, Alexander, Esq,

Edinburgh; Mitchell, Arthur, NID., Edinburgh; Mitchell, Rev. Dr. Ml.,bturgh; Moffat, Robert, M.D., Falkirk; Moir, F. L. Ml., Esq., London; Mloir,John, M.D., Edinburgh; Mloir, John, Esq., E-dinburgh; Aloir, John W.,Esq.,London; Montgomery, A. F. Lyons, Esq., Sandhturst; Mlontgomery, J. Barclay,

M.D., Penzance; Montgomery, 1. Lcwther, Esq., Ayton; Moodie, Robert, Esq.,

Stirling; Moore, George, MI.D., Hartlepool; Aloore, John, AM.D., Belfast; Alore-ton, J. E., Esq., Tarvin, Chester-; Morgan, G. B., Esq., Sunderland; Morgan,

Ilerbert, Esq., Lichfield; Mlorgenrood, William G., Esq., Cape of Good Hope;

Morham, Robert, jun., Esq., Edinburgh; Morison, Alexander, M\.B., London;

Morley, John, Esq., Barton-on-Humber; Alorris, James, Esq., Duinfermline;

Morris, John, Esq., Baltimore ; Morris, Malcolm, Esq., Goole; Morrison, J. D.,

Esq., Edinburgh; Mortimer, William, I.D., 'itirriff; Mlortoni, James, M.D.,

Glas-ow; MIostyn, Berkeley, MI.D., New York; MIould, G. W., Esq, Manchester;

Moiitry, T. V., Esq., Mauritius; Muir, Robert, Esq., Havick; Aluirhead, Claiid,

M.D., Edinburgh; AMuillan, Andrew, M.D., Ballymena; Alungall, Robert, M.D.,

Lochgelly; Mlurch;son, C., M.D., F.R.S., London; Mlurphy, 0., Esq.,

Alanchester; Mlrphy, James, Esq., United States; Murray, David, AI.D.,burgh; Mlurray, John, M.D., Forres; Mluschet, J. S., MI.D., Stirlin.

Nachot, H. W., Esq, Edinbargh; Nairne, Alexander, Esq., Fauldhouse;

Nairne, C., Esq., Perth; Nairne, J. S., Esq., Fauldhotuse; Napper, Albert, Esq.,

Cranleigh; Neal, B., Esq., Birntingham; Nelsoni, W. D., Esq., Lochgelly;

field, Steplhen, M.D., Manchester; Niblett, T. B., Esq., Everton; Nicholson,

H. B., Esq., Hull; Nicholson, T. D., M.D., Clifton; Nicol, Auidrew, Esq.,burgh; Nicolson, Davidc, I.B., Portsmouth; Niehaus, Paul, Berne; Niver, John,

Esq., Edinburgh; Nornman, J. H., Esq., Mauritius; Norton, T., Esq.,

London.

O'Brien, Richard, 1M.D., Tipperary; Odell, William, Esq., Hertford;

George S WV., Fsq., Edinburgh; Ogston, F., jun., M.D., Aberdeeui;

George. AI.D., Harroiate; Osburn, C., Esq., Cork; Otis, F. N., M.D.,

York; Owen, Harvey K., M.D., Clapham.

Pacchiotti, Professor, Italy; Page, David, M.D., Kendal; Page, Frederick,

MI.D., Newcastle-on-Tyne; Panton, George Esq., Edinbuirgh; Parsey, H.,

.LD., Hatton; Parsons, Charles, MI.D., Dover; Parsons, WV., Esq Wimble-don; Paterson, Alexander, Bridge Allan; Paterson, G., Ml.D., Edinburgh;

Paterson, Johni, Esq., Cornwall; Paton, J., Esq., Edinburgh; J. B., Esq.,

Edinbturgh; Paxton, John, Esq., Norham; Pearce, WV. Grindlay, Esq.,

Pearson, William, Esq., Glasgow; Peddie, A., M.D., Edinburgh; Peniberton, O.,Esq., Birmingham; Perry, Robert, M.D., Glasgowv; Esq.,ford; Philipson, G. H., M.D., Nesvcastle-on-Tyne: Phin, Ml.,burgh; Pickles, John J., Esq., Leeds; Piper, E., Esq., Darlington; Pirie,M.D., Glasgoss; Pirrie, William, MI.D., Aberdeen; Pitts,

sey, Leeds; Platt, Thomas, Esq., Oldham; Playfair, Johin, MI. Edinbtirgh;Plavfair, Right Hon. Lyon, MI.P., London; Pope, Edmtind, Esq., London;

J. W., Esq., Yorkshire; Prentice, J. G., Esq., Edinburgh:; Prichard,

Esq, Bristol; Priestley, W. D., l. D., London; Procter, l\1.D., York;

Prust, Rev. MIr., Edinburgh; Purnell, J. J., Esq., London; Purves, P., Esq.,

Edinburgh; Pitirves, W. Laidlawv, MI.D.,Rae, James, M.D., Stirling; Raitt, Thomas, M.D., Accrington; Raitt, William,

Esq, Edinburgh; Rajamah, Madagascar; Ransom, Frederick, Esq., Sutherland;

Ransom, W. H., MT.D., F.R.S., Nottingham ; Rattray, A. Il. T., AlI.D., Portobello;

Reeves, William, M.D., Carlisle; Reid, J. C, MI.D., Newbiggin1;C., Esq., Leith; Reilly, F. J., Esq., London; Retiny, W., Esq.,

Rentoin, Alexander A., k:sq, Edinburgh; Renton, John, Esq., Boston;

Crawford, l. B., Glasgow; Renton, W. H., MI.D., Shotley Bridge;

Ruissell, M.D., F. R. S., London; Rhodes, George W., Esq.,

J. Esq., Bradford: Rice, George, Esq., States; Richards,John, L.K.Q.C.P.,

Banigor; Richardson, Alexander, Esq., Edinburgh Richaruson, Ralph, Esq.,

Ediiiburgh; Richardson, R. J., Esq., Lockerbie; Rider, J., Euq, Wellington,Salop; Ritchie, Andrew, MI.D., Pollokshaws- Ritchie, James, M.B.,burgh; Ritchie, J. J., Esq Leek; Ritchie, Peel, M.D., Edinburgh; Ritchie,

Thomas, Esq., Otley; Rivington, Walter, Esq., Londoni; Roberts, Frederick T.,

M.D., London: Roberts, Robert, Esq, Portmadoc; Roberts, WVilliam, M.D.,

Mlancliester; Roberts, W. A., Esq, Edinburgh; Robertson, Alexanider, M.D.,

Glasgow; Robertson, A. MI., Esq., Glasgow; Robertson, Argyll, Mi.D.,burgh Robertson, John, Esq.. Edinburgh; Robertson, J., Ml.D., C;ockermouth;Robertson, R. T. C., I.B., Hamilton; Robertson, W., Esq., Newvington;son, WVilliam, NI.D., Glanton, Alnwick; Robinson, H., L.K.Q.C.P., Fintona;Robinson, HI., Esq., Chestesfield ; Robson, NI., Esq., Durham; James,

Esq., Souith Shields; Robson, R. N., Esq, Durham; Rodger, James, NIB.,

deen; Roger, Henri, NI.D., Paris; Rogers, Joseph, NID., London; T.

L., NI.D., Rainhill Rollo, Hugh J., Esq., S., Edinburgh ; Roinaldson,T. R., M.B., Edinbturgh; Rose, Donaldson, Esq., Brechin; J., Esq.,

Brechin; Rose, David, M.D., South Shields; Ross, ANc, L.K.Q.C.P., Nlona-

ghan; Ross, George, I.D., London; Ross, James, M.D., Waterfoot, Nlanchester;Roy, Charles S., E-q., Arbroath; Rugg, George P., NI.D., London; Russell,

James A., Esq., Edinburgh; Rutherford, James, INID.., Glasgow; Rutherford,

Rev. Thomas, Edinburgh; Rutherford, William, N\I.D., Edinburgh; Ryan,

Esq., Melbourne; Ryan, Philip NI., Esq.,

handeman, Alfred, E.cq., Aberdeen; Sanderson, Alfred, Esq., Edinburgh;

derson, A. NI., Esq., Nlusselburgh; Sanderson, Charles E., Esq., Edinburghl;Sanderson, J., Esq., Ediniburgh; Sanderson, J. Biirdon, NM.D., London;

Satindby, Robert, NI. B., Edinburgh ; Saunders, George, C. B., . D.,

Savage, James, Esq., Bridlington; Schenck, L., Esq., York;

H., I. B., Edinbturgh; Scott, Thonmas R., juin., M.B., Nlusselburgh ; Sealy, George

J., Esq., XVeybridge: Shann, George, NI.D., York; Shapter, Thomas, NID.,Exeter; Sherburn, John, Esq., Yorkshire; Sheriff, Thomas, Esq., Ratho;

Richard C., D., Readling; Shiell, W. R., Esq., Melrose; Shuttleworth, E.,

NID., Lancaster; Sibbald, John, NI D., Edinburgh; Sibson, lrancis, NLD.,F.R.S., London; Silvcr, Alexander, NID., London; Simpson, R.,

Edinburgh; Simpson, James, Esq., Eastwood; Simpson, W. R., Esq., Ediilburgh;

Sept. 4, 1875.] 313

314 THE BRITISH MEDICAL _QURNAL. [Sept. 4, 1875.

Sinclair, A. WV., M.D., Edinburgh; Sinclair, Alexander J., M.D., Edinburgh;Sinclair, D., £.sq., Halstead; Sinclair, James E., Esq., Edinburgh; Sinclair,Veitch, E,Q., Edinburgh; Skeate, Edwin, Esq., Bath; Skinner, N., Esq., Keith;Skinner, William, Esq., Edinburgh; Sloan, Samuel, M.D., Glasgow; Smart, W'.R. E. M.D., Haslar; Smeddle, R., Esq., Shildon; Smith, A. H. B, Esq., Lon-don: Smith, Aubrey, Esq, Devon; Smith, George, Esq., Edinbuirgh: Sillith, G.W., Esq., Edinburgh; Smith, John, M.D., Duimfries; Smith, John, M. D., Edin-lssrgh; Smith, John A., M.D., Edinburgh; Smith, John M., Esq, Edinburgh;Smith, J. G. Malcolm, Esq., London; Smith, J. S., Esq., Edinburgh; Snolth, Pro-theroe, M.D., London; Smith, Thomas, Esq., London; Smith, Thomas, MI.D.,Cheltenham; Smith, William, Esq., Fallowfield, Manchester; Smith, William,Esq., Andover; Smith-Shand, J. W. F., M.D., Aberdeen; Smythe, Robert, Esq.,Edinburgh; Snape, G. H., Esq., Liverpool; Solomon, J. V., Esq, Birmingham;Somerville, A. T., Esq., New Brunswick; Somerville, Robert, AM.D., Galashiels;Spalding, William, M.D., Guebridge; Spence, A. Blair, Esq., Dundee; Spence,James, Esq., Edinburgh; Spence, Robert, M.B., Buruitisland; Spencer, L. D.,M.D., Indian Army, London; Sproston, W. H., Esq., Birmingham; Stainthorpe,Thomas, M.D., Hexham; Stark, B. S., Esq., Barrow-in-Furness; Steele, A. B.,L.K.Q.C.P., Liverpool; Steele, Henry, M.D., Montrose; Steel, G. Carrick, Esq.,London; Stephen, William, M.D., Currie; Stephenson, G. Skelton, Esq., Grimsby;Stephenson, William, M.D., Edinburgh; Stephenson, W. H., M.D, Blackburn;Stevens, Jarmes, Esq., Ardrossan; Stevens, W. Goldie, Esq., Renfrew; Stewart,A. P., M.D., London; Stewart, Peter, MI.B., Durham; Stewart, R. F., Esq.,Edinburgh; Stewari, T. Grainger, M.D., Edinburgh; Stewart, Walter C., Esq.,Leghorn; Stewart, William, M. B., Kirkwall; Stewart, William, Esq., Dalkeith;Stirling, D. H., M.D., Perth; Stirling, W., M.D, Edinburgh; StoLks, A. W.,Esq., Salford; Stockwell, James, Esq., Ormskirk; Stockwell, T. G., Esq., Bath;Stodart, S. T., Esq., Edinburgh; Stone, Herbert S., Esq., New Brunswick;Stone, T. AMadden, E&q, London; Strachan, John M., M.D., Dollar; Strange, W.H., M.D., London; Struthers, John, MI.D., Aberdare; Stuart, Thomas R., Esq.,Edinburgh; Summers, T. O., Esq., Nashville; Sutherland, Daniel, Esq., Edin-burgh; Sutherland, Henry, M.D., London; Swain, Pauil W., Esq., Devonport;Swan, William, Esq., St. Andrew's; Swanzy, H. R., M. B., Dublin; Swayne, J.G., M.D., Clifton; Symons, Mark S., Esq., Dumfries; Sympson, T., Esq.,Lincoln.

Tait, Lawson, Esq., Birmingham; Tait, William, Esq., Edinburgh; Tawse,John, Esq., Edinburgh; Taylor, Charles Bell, M.D., Nottingham; Taylor, John W.,Esq., Gateshead Dispensary, Preston; Taylor, Michael W., M.D., Penrith;Taylor, William, M.D., Ediniburgh; Tlaylor, William, M.D., Cardiff; Thatcher,L. H., M.D., Edinburgh; Thimbleby, John, Esq., Spilsby; Thom, Alexander,Esq., Crieff; Thomas, Benjamin, Esq., Llanellv; Thomas, Jabez, Esq., Swansea;Thomas, M., M.D., Glasgow; Thoinas, Richard H., Esq., Baltimore; Thomas,Robert, Esq., Rawdon, Leeds; Thompson, James, M.B., Leamington; Thom.on,George W., M.D., Hawick; Thomson, G. L., M.D., Hants; Tlhooison, Hugh,M.D., Glasgow; Thomson, Jolin, M.B., Edinburgh; Thomson, J. Roberts, M.D.,Bournemouth; Thomson, S., Esq., Glasgow; Thomson, Spencer, MI.D., Torquay;Thomson, Thomas, Esq., Inveresk; Thomson, T. Drutinmond, Esq., Edinbureh;Thomson, W. Burns, Esq., Edinburgh; Thyne, Thomas, M.D., London; Tiffen,Robert, MI.D., Wigton, Cumberland; Todd, James, Esq, Killin; Tomkins, W.Fancourt, Esq., Yeovil; Torrance, Robert, Esq., Matfen; Forrance, Thomas, Esq.,Airdrie; Torrie, L. J., Esq., Edinburgh; Totherick, James V., ,M.D., Wol-verhampton; Trail], John, Esq., Arbroath; Tiike, John Batty, M.D., Edinbuirgh;Tulloch, David, M.B., Helmsdale; Tunstall,A. C., M.B., Edinburgh; Turnbull,J. Rutherfoord, Esq., Edinburgh; Turnbull, AM. J., M.D., Coldstream; lurner,J. S., Esq.; Turner, R. S., M.D., Keith; Tweedy, John, Esq., London; Tyle-*cote, E. T., M.D., Great Haywood.

Underhill, Charles E., M.B., Edinburgh; Underhill, Thomas, M.D., WestBromwich.Valentine, Colin, Esq., Jeypore; Veale, Richard S., M.AD., Leeds; Vetch,

Charles, Esq., Haddington.Wade, W. F., M. B., Birmingham; Waldron, Derwent, Esq., Jamaica; Walker,

Hunter W., Esq., Edinburgh; Walker, George, Esq., Birkenhead; Walker, J. B.,M.D., Huddersfield; Walker, Robert, M.D., Wooler; Walker, T. Shadford, Fsq.,Liverpool; Wall, A. B., Esq, Bayswater; Wallace, A., Esq., Glasgow; Wailace,-, Esq., Kinsale; Wallace, John, Esq., Leith; Walley, Thomas, Esq., Edin-burgh; Walsh, Tohn, L.K.Q.C.P., Stoneyhurst; Walton, John, Esq., Birming-ham; Waters, A. T. H., M.D., Liverpool; Waters, Edward, M.D., Chester;Watson, M., Esq., Lancaster; Watson, Patrick Heron, M.D., Edinburgh;Watson, T. Boswall, Esq., New Brighton; Watson, Thomas H., il. B., EdinbuLrgh;Watson, W. F., Esq., Edinburgh; Watson, W. Tyndall, MI.D., Tottenham; Way,John, M.D., London; Webb, Charles, Esq., Basingstoke; Webb, William, Ai. D.,Worksworth; Webster, Henry, Esq., London; Webster, Thomas, Esq., Bristol;Weir, J. W., M.D., Glasgow; Weller, George, Esq., Wanstead; Wells, T. Spencer,Esq., London; Welsh, T. T., Esq., Bombay; Wtmyss, A. W., M.D., St.Andrew's ; Wemyss, John W., MI.D., Broug-hty-Ferry; 'West, E. L, Esq.,Launceston; Wharton, J., L.K.Q.C.P., Oldham; Wheatley, Thomas D., M.D.,Oporto; Wheeler, D., Esq., Chelmsford; White, Surgeon-Major, Edinburgh;White, G. I., Esq., Aberdour; White, James, Esq., Wigan; White, John, Esq.,Edinburgh; White, Joseph, Esq., Nottingham; White, T. Charters, Esq., London;Whitelaw, William, M.D., Kirkintilloch; Whiteley, John, Esq., Wakefield; Whit-taker, James Travis, M.B., Glasgow; White, John, MI.D., Aberdeen; Wight,John, Esq., Edinburgh; Wilkinson, Auburn, Esq., Tynemouth; Wll, J. C. Ogil-vie, M.D., Aberdeen; Williams, J. M.D., Pontypool; Williams, W., Esq., Edin-burgh; Williams, W. Rhys, M.D., London; Williamson, Thomas, MI.D., Leith;Willis, G., Esq., Baillieston, Glasgow; Willmore, F. W., Esq., Walsall; Wilson,Alexander, M.B., Motherwell; Wilson, Alexander, M.D., Mid-Calder; Wilson,David, M.D., Edinburgh; Wilson, F. W., M.B., London; Wilson, George, M.D.,Leamington; Wilson, H., Esq., Coatbridge; Wilson, John, M.D., Inverness;Wilson, John, Esq., Kirriemuir; Wilson, Robert, M.D., Alnwick; Wilson,Thomas, Esq., Wallsend-oii-Tyne; Wilson, William, M.D., Florence; Winchester,J. W., Esq., Edinburgh; Wise, R. Stanton, M.D., Banbury; Wolfe, J. R., M.D.,Glasgow; Wolston, Walter I. P., M.B., Edinburgh; Wood, Miles A., Esq., Led-bury; Woodcock, Alex., Esq., Anstruther; Worley, W. C., Esq., London;Wortabet, H. G. L., Syria; Wright, J. B., M.D., Welliogborough; Wright, Mat-thew Hall, Esq., Birmingham; Wylie, James, Esq., Errol.

Yeld, Henry John, M.D., Sunderland; Yellowlees, D., M.D., Glasgow; Young,David, M.D., Florence, Italy; Young, James, M.D., Edinibturgh; Young, JamesWilliam, M.D., Dublin; Young, P. A., M.D., Portobello; Young, Thomas, Esq.,South Shields; Young, W. Butler, Esq., Reading.

Zeigler, W., M.D., Edinburgh.

REPORTS OF SOCIETIES.MEDICO-CHIRURGICAL SOCIETY OF EDINBURGH.

JULY 7TII, IS75.RUTIIERFORD IHALDANE, lI.D., President, in the Chair.

Exhibitiont of Potiiezkts.-Dr. GRAINGER STE\VAR'r showed: i. Asailor who had been paralyzed in consequence of spinial curvature, hadimproved under treatment so as to return to sea, buit, after long exert-ion in bad weather, had again become paraplegic. Ile wvas again muchimproved by treatment. 2. He also showed a mani suffering fromsclerosis of the posterior columns of the cord. The muscular sense,which gives the power of appreciating weight, wvas lost in the limbs, andthe cutaneous sensibility nearly gone. 3. I-He also showed a case ofmuscular atrophy in a blacksmith, chiefly confined to his forearms andlegs. It had been progressing slowly for twenty years. 4. lIe alsoexhibited a case of bronchiectasis, which illustrated the symptoms well,especially the peculiar factor of the sputum; and 5. A yotung girl whoappeared in tolerable health, but who was suffering from advanceddisease of the kidney.

Exhibition of.Specirmens. -Dr. HALDANE exlhibited the parts removeedfrom a very remarkable case, wlhich he had seen once only before death.The history was briefly as follows. A healthy militia sergeant hadhad diarrhcea, etc., and had been sent in from the regimental hospital.lie was jaundiced, and vomited dark matter, stained with blood. Theurine, which was exceeding scanty, was highly albuminous. The liverwas not diminished in size. The symptoms were those of acute yellowatrophy of the liver. No treatment could be of use, and he died a fewhours after admission, with his mind clear to the last. The necropsyshowed the liver to be 41bs. in weight, not much altered. The kidneyswere enlarged and contained tubercular abscesses. There was no ulcerof the stomach, but the pancreas was enlarged, softened, and infiltratedwith blood. He believed the case was one of great rarity and obscurity.

MIr. ANNANDALE showed a good specimen of cartilaginous tumourof the tibia, treated by amputation; a case of necrosis of the tibia ;two-thirds of a cancerous tongue, along with diseased submliaxilliaryglands, which he had recelntly removed; an epit-helial growth on thepenis, in a man aged 32, which he had recently removed without re-moving the whole or-gan; and a head of a femur excised in early hip-disease.

Mlr. J. CHIENE showed a loose cartilage excised from a knee-joint,under carbolic spray.

Dr. ANC.US MACDONALD showed an intestinal concretion removedby Dr. TURNER of Keith, frolmi the rectum. It was a gall-stone in-crusted with hairs from a caryopsis, mixed with saline matter.

History of a Completed Cose of Recurrent Tumtour. By JAmESSPENCE, Esq.-This paper was a most careful and complete accountof a case of extreme rarity. The facts were briefly as follows. Mrs. E.consulted the late Dr. Maclagan in I832. She was then twenty-twroyears of age, and showed a tumour of three years' standing in the leftloin ; firm, elastic, and as large as a jargonelle pear. This tumour wasremoved. In IS34, and again in I836, other tumours, similar in cha-racter, appeared in the scar, and were removed by Dr. Douglas 'Mac-lagan. Not till I857 Nvas she again under treatmelnt, when ProfessorSyme was asked by Dr. Douglas MIaclagan to see her, wvith a view to

the removal of another tumour which had made its appearance in thescar about a year before. It was now about the size of half an orange,elastic, irregular, and, on its most prominent part, preseilted a pinktransparenit appearance. The tumour and scar vere lnow again widelyremoved, along with a portion of lumbar fascia. Her general healthwas excellent; nor was there a symptom of cachexia. The wotndhealed well, and the tumours never returned. Sir James Paget andDr. lIaldane, who at the time examined the tumour, described itsstructure as fibrous tissue, containing nucleated cells of an elongatedoval form. In November i868, the patient returned with a tumour ofthe size of half a small melon on the right mamma, the nipple of whichwas retracted. There was nio glandular involvement. Her health was

good, and she looked well. In August 1870, she returned with a

tumour in the vicinity of the scar of the last operation, but not in it.This tumour was as large as a small lemon. This was removed, and,on her convalescence from the operation, she had symptoms of stricture

of the oesophagus, which, however, seemed to pass off, and wvere sup-posed to be nervous in origin. In June I87 i, after a visit in thecountry, she caught cold, had bronchopneumonia and pericarditis, wasunable to swallow, had an ulcerated tumour in the axilla, alnd diedexhausted very rapidly. The post mortemn examination was made byDr. Wyllie. The body was somewhat emaciated; face pale and sallow.

318 THE BRITISH MEDICAL 7URNAL. [Sept. 4, I875.

ing the sick from the healthy, etc., prevented it from becoming theserious affair it would have become in any place under bad manage-ment or surrounded by unhealthy conditions. The last cases I havevisited occurred in the parish of St. Giles, in the Torrington Union,where there have been one or two deaths. But wvhether at H-igh Bick-ingtoni, at Bickleigh, at Clovelly, or at Ilfracombe, unless it could bedistinctly traced as carried by actual contact, it has occurred exclusivelyon lofty, airy, and open situations. I must, at the same time, say thathitherto in each case in my own district the drinking water has beenundoubtedly polluted. So far, then, as I have gone, there are twofairly constant companions of diphtheria-high situations and pollutedwater. Subsequent observation will, perhaps show whether these aremere unimportant coincidences or not."

POOR-LAW MEDICAL APPOINTMENTS.BAINES, Egertori C. A., M.R.C.S., appointed Medical Officer to the NettlebedDis-

trict of Henley-on-Thames Ui,ion' vice W. S. J. H. Mlunro, Al.)., resigned.BUTLER, Edmund Fitzgerald, L.R.C. S.I., appointed Medical Offi er and Ptublic

Vaccinator for the Boston District and the Workhouse of the Boston Union, viceW. H. Radley, M. R. C. S. Eng., resigned.

CRAWFORD, James, M.D., appointed Medical Officer for the Manningham Districtof the Bradford Union, Yorkshire, vice E. Suigden, M.R.C.S.Eng., deceased.

CLARK, Wm. W., MI.D., appointed Medical Officer to the Workhouse and the Wel-lingborouigh District of the Wellingborough Union.

DAVIES, John, M.D., appointed Medical Officer for the Ebbw Vale District of theBedwelty Union; vice Alexander Brewer, MI.R.C.S.Eng., resigned.

DAVIs, Henry H., M. R. C. S., appointed MIedical Officer for the Llandyssil Districtof the Newcastle-in-Emlyn Union, vice T. Jones, M.R C. S., deceased.

GuPpy, Thomas S., M.D., appointed MIedical Officer for the Constantine District ofW the Falmouth Union, vice E. H. Eykyn, M.R.C.S., resigned.GRIFFITHs, D., M. B., appointed Medical Officer for the Llandilotalybont District

of the Swansea Union, vice T. M. Jones, M. R. C. S., resigned.HAIR, James, M.D., appointed Medical Officer for the Eighth District of the Lex-den and Winstree Union, vice H. D. Palmer, AT.R.C.S., resigned.

HOPE, John, M. D., appointed MIedical Officer for the Chobham District of the Chert-sey Union, vice S. M. Ward, M.B., resigned.

THOMAS, Richard R. G., M.D., appointed Mledical Officer and Public Vaccinatorfor the Tiverton West District of the Tiverton Union, vice J. Reddrop, Ml.R,C.S.Eng., resigned.

WfLLIAMs, David W., M.D., appointed Medical Officer to the Workhouse, Port3eaIsland Union, vice T. Diver, M.D., resigned.

OBITUARY.EDMUND BURTON RAVENHILL, MI.R.C.S., L.S.A.,

WOLVERHAMPTON.WE regret to announce the sudden death of this young and talentedpractitioner. Mr. Ravenhill was the second son of the Rev. T. H.Ravenhill, M. A., Vicar of Arlingham, Gloucestershire. He receivedhis medical education at the Queen's College and the Queen's Hospital,Birmingham. At the College, he gained several distinctions. At theQueen's Hospital, he held in succession, each for six months, theoffices of Resident Surgeon's Assistant, Resident Physician's Assistant,and Resident Obstetric Assistant, to all of which appointments he waselected after competitive examination. He became a member of theRoyal College of Surgeons and a Licentiate of the Society of Apothe-caries in 1870, and he was shortly afterwards elected to the housc-surgeoncy of the South Staffordshire General Hospital at Wolver-hampton, which post he held with credit for nearly four years. Abouta year ago, he engaged in private practice, and he soon afterwardsmarried. Mr. Ravenhill had lately become subject to attacks of gastro-intestinal catarrh, and his health had been much impaired by his devo-tion to his work. For a few days before his death, he had sufferedfrom occasional but slight vomiting and abdominal pain, but there wasnothing in his condition to cause anxiety to his relatives. He died veryunexpectedly, probably from syncope, on August 23rd, in the twenty-seventh year of his age. Mr. Ravenhill had a promising career beforehim. His kind manner and gentle disposition had endeared him tomany friends.

MEDICAL NEWS.APOTHECARIES' HALL. -The following gentlemen passed their ex-

amination in the science and practice of medicine, and received cer-tificates to practise, on Thursday, August 26th, 1875.

Dobbie, Robert John Algernon, Budleigh SaltertonLaird, John, 4, Palace Street, PimlicoLewis, Edwin Alaric, Loraine Road, HollowayOldham, Samuel, Burslem, StaffordshireSargent, Arthur Francis, Lancaster Place, BelsizeUpton, Alfred, Petworth, SussexWorswick, Frederick Henry, Hulme, Manchester

The following gentlemen also on the same day passed their primaryprofessional examination.

Archer, Robert Kendray, Westminster HospitalCox, William Laird, St. Mlary's HospitalCreswell, William George, Queen's, Birmingham

At the recent examination for the prizes in Materia Meldica andPharmaceutical Chemistry, the successful candidates were :-i. Fredk.Freer Leslie Robertson, St. Bartholomew's Hospital, the Gold Medal;2. Neville Scott Whitney, University College, the Silver MIedal anda Book.

MEDICAL VACANCIES.THE following vacancies are announced:-

BLACKBURN and EAST LANCASHIRE INFIRMARY-House-Surgeon.Salary, Zioo per annium, with board, lodging, and washing. Applications onor before the i4th instant.

BOURNEMOUTH GENERAL DISPENSARY-Resident Medical Officer andSecretary. Salary, £120 per annum, with furnished apartments, coals, gas,and attendance.

BRISTOL LUNATIC ASYLUNI-Assistant MIedical Suiperintendent. Salary,Lioo per annum, with fuLrnished apartments, board, and washing. Applica-tions on or before the i6th instant.

CARNARVON UNION-Medical Officer for the Llandwrog District. Salary,£6o per annum.

COLCHESTER UNION-Medical Officer for the Second District, Salary,£75 per annum.

DISPENSARY FOR SICK CHILDREN, Manchester-AAssistant MedicalOfficer. Salary, £,Io per annum. Applications on or before September I5th.

DUNDEE ROYAL INFIRMARY-Resident Medical Assistant. Salary, £70per annum, with board, lodging, and washing. Applications on or before thes5th instant.

HOSPITAL FOR SICK CHILDREN, Manchester-Assistant Physician.Salary, L6300 per annum. Applications on or before Septenmber i5th.

INVERNESS DISTRICT ASYLUNI-Assistant Medical Officer. Salary, £70per anntum, with bed, board, and washing. Applications on or before theixth prox.

MARTLEY UNION-Medical Officer for No. 4 District. Salary, £85 per annum,and fees. Applications on or before the gth instant.

NORWICH DISPENSARY-Salary, sa20 per annum, with unfurr.ished resi-dence and apartments.

PEMBROKE UNION-Medical Officer for the First District.QUEEN'S HOSPITAL, Birmingham-House-Physician. Salary, £50 per annum,

with board, lodging, and washing. Applications on or befoue the 23rd instant.ROYAL SOUTH HANTS INFIRMARY-House-Surgeon. Salary, L8 per

annum, with board, lodging, and washing. Applications oti or before Sep-tember 6th.

ROYAL UNITED HOSPITAL, Bath-House Surgeon. Salary, 6oper annum,with bsard and residence. Applications on or before the 22aid instant.

ROYSTON UNION-Medical Officer for No. 5 District. Applications on orbefore September 6th.

ST. GILES-IN-THE-FlELDS and ST. GEORGE, BLOOM SBEURY, Parishes-Medical Officer. Salary, £250 per annum.

SHEPTON MALLETT UNION -Medical Officer for the Fourth District.Salary, £32 per annum.

STAINES UNION-Medical Officer for the Shepperton District.STROUD GENERAL HOSPITAL-House-Surgeon.WARWICK COUNTY LUNATIC ASYLUNM-Second Assistant Medical Officer.

Salary, Zioo per annum, with board, lodging, and washing.WIMBORNE and CRANBORNE UNION-Medical Officer for No. I and 2

District and Workhouse. Salary, £85 per annum for No. I, and £75 for No.2, with L2o additional for the Workhouse. Applications on or before the23rd instant.

WORCESTER GENERAL INFIRAIARY-Physician. Applications on orbefore the 2ath instant

YORK DISPENSARY-Resident Medical Officer. Salary, £130 per annuim, withfurnished apartments, coal, and gas. Applications on or before the s6th inst.

MEDICAL APPOINTMENTS.Names marked with an asterisk are those ofMembers of the Association.

FoWLER, George, M.R. C. P. Ed., appointed Physician to the North London Hospitalfor Consumption and Diseases of the Chest.

*REID, Douglas A., M.D., appointed Consulting Surgeon to the Pembroke Dis-pensary and Infirmary.

SHERBURN, John, M.B., appointed Assistant House-Surgeon to the Hull GeneralInfirmary.

WALTER, William, B.A., M.B., appointed House-Physician to the North Stafford-shire Infirmary, Stoke-upon-Trent.

BIRTHS, MARRIAG1ES, AND DEATHS.The charge for inserting announcements of Births, Marriages, and Deaths

is 3s. 6d., which shouid be fob warded in stamjhs with the communication.BIRTH.

LYNES.-On August 26th, at 9, Priory Row, Coventry, the wife of *Edward Lynes,MD., of a son.

DEATH.HENRY, George, L.R.C.P.Ed., at the residence of his brother (Emerson W. Henry,M.D.), Lowther Street, Whitehaven, aged 29, on Auglust 27th.

THE Clayton Hospital and Wakefield General Dispensary is to beremoved to a new site, and £8750 has already been subscribed towardsthe cost of the land and new building; for which the Committee askof the public /I 5,000. Amongst the subscriptions are two of £iooo,and several of £500.

Sept. 4,1875.] THE BRITISH MEDICAL 7OURNAL.

OPERATION DAYS AT THE HOSPITALS.

MONDAY .......Metropolitan Free, 2 P.M.-St. Mark's, A.M. and P.M.-RoyalLondon Ophthalmic, iI A.sX.-Royal Westminster Ophthalmic,1.30 P.M.

TUESDAY ...... Guy's, 1.30 P.M.-Westminster, P.M.-Royal London Oph-thalmic, It A.M.-Royal Westminster Ophthalmic, I.30 P.M.-West London, 3 P.h.-National OrthopediC, 2 P. M.

WEDNESDAY, .St. Bartholomew's, 1.30 P.r1.-St. Mlary's, 1.30 P.Mi.-Middlesex,x P.s.-University College, 2 P. M.-St. Thomas's, 1.30 P. Mt.-Lon-don, 2 P.rst.-Royal Londoii Ophthalmic, A. st.-Great Northern,2 P.AS.-Samatitan Free Hospital for Women and Children, 2.30

P.M.-Cancer Hospital, Brompton, 3 P.st.-King's College, P'.st-Royal Westminster Ophthalmic, t.so P.M.

THURSDAY.. ..St. George's, P.sm.-Central London Ophthalmic, x P.M.-RoyalOrthopadic, 2 P.M.-Royal London Ophthalmic, ti A.M.-Hos-pital for Diseases of the Throat, 2 P. M.-Royal Westminster Oph-thalmic, 1.3o P. M.-Hospital for Women, 2 P.M.

FRIDAY......... Royal Westminster Ophthalmic, 1.30 Psi. Royal London

Ophthalmic, it A.i. -Central London Ophthalmic, 2 P. M.-RoyalSouth London Ophthalmic, 2 F..m.

SATURDAY ..St. Bartholomew's, I. o P.pM.-King's College, t.30 P.iM.-CharingCross. 2 P.M.-Royal Loiidoii Ophthalmic, It A.M.-East LondonHospital for Children, 2 i'.ms.-Royal Westminster Ophthalmic,1.0o i.mu.-St. Thomas's,9.30 A.M.-Royal Free, 9A.M. and 2 I.M,

NOTICES TO CORRESPONDENTS.CORRESPONDENTS not answered, are requested to look to the Notices to Corre-

spondents of the following week.

PUBLIC HEALTH DEPARTMENT.-We shall be much obliged to Medical Officers ofHealth if they will, in forwarding their Annual and other Reports, favour us withDuplicat* Copies.

AUTHORS desiring reprints of their articles published in the JOURNAL, are requestedto communicate beforehand with the printer, Mr. T. Richards, 37, Great QueenStreet, W.C.

CORRESPONDENTS, who wish notice to be taken of their communications, shouldauthenticate theni with their names-of course, not necessarily for publication.

WE CANNOT UNDERTAKE TO RETURN MANUSCRIPTS NOT USED.COMMUNICATIONS respecting editorial matters, should be addressed to the Editor:

those concerning business matters, non-delivery of the JOURNAL, etc., should be

addressed to the General Manager, at the Office, 36, Great Queen Street, W.C.

DR. BROUGHAMI (Sheffteld).-The following is the by-law on the subject. " No Fellowor member of the College of Surgeons shall advertise or publish any matter or

thing prejudicial to the interests or derogatury to the honotr of the College, or

disgraceful to the profession of surgery; and any Fellow or member who may in

any manner offend herein shall be liable to be removed, by resolution of the Coui-cil, from being a Fellow and member or member of the College." (Section xtii,par. a.)

2oCTORS OF EDINBURGH AND ERLANGEN.

Siee,-Adverting to the letter of" l.D.Erlangen, L.R.C. P. London", in this day'sissue of your admirable JOURNAL, may I be allowed to observe, in the interests

of truth and justice, that the whole question of registration or recognition of

foreign degrees is still in a most unsatisfactory state, and must yet be fairlyadjusted? The Geteral Medical Council, as you are well aware, promised, at itsrecent session, "to take into consideration whether, with a view of furthering the

desire of extended accomplishment in meediciiie and science among the members of

the medical profession, it may be advantageotts to make it lawful for the Council

to insert in the Medical Register (after the name of a person registered ois other

qualifications, etc.) the appropriate title indicative of a degree obtained after

study and examination in a foreign University". Surely it cannot be supposed,in the year 1875, that " science and medicine" are restricted to the British Isles.

Erlangen is proving the contrary by her 'clo(sia, etc. Why, therefore, shouldthe M.D. of Edinbstrgh be inserted in the Register by the Council, and that of

Erlangen be ignored or rejected, in the following circtimstances "Candidates

settled in foreign parts, who have complied with all the regulations for the degreeof M. D.Edin., but who cannot appear Aersonally to receive the degree, may, on

satisfying the Senatus to that cffect by prodsiction of official testimonials, have

the degree conferred on then in absence." (Statute xvii.) Now, sir, in common

with Pereira, Ashwell, Lever, Waller, Brande, Davies, and several others, the

degree of M.D. was conferred upon myself "in absence", agreeably to the

enlightened recognition, as I cotuceive, of British diplomas and "official testimoni-als" from Lawrence, Brodie, Cooper, Bright, Addison, Babington, etc. -in short, thebest blood of " science and medicine" in this country-together with the exhibitionof half-a-dozen published octavo volumes pertaining to physic or physical science,more than thirty years ago; and is it just that not only she Medical Register, but

the Mfedical Directory, should be closed against the insertion of such medical

degrees, and granted long before the passing of the Medical Act, whilst, in the

face of fair play, or rather with open injustice to foreign graduates, physicians'licenses, surgeons' diplomas, and honorary doctors' degrees, obtained in Great

Britain and Ireland u'iihout personal exnamioailion, are recognised and registeredby hundreds upon hundreds? Having subsequently graduated in " medicine and

science" at a Prussian or Italian University. after residence astd exantination, the

question at issue does mot specially interest myself-a man, moreover, far ad-

vanced in the " sere and yellow leaf" from matter to spirit; but I think the

editors of the BRITISH MxEDICAL JOURNAL, pioneers of progress in science and

medicine, ought in this, as in other subjects, to be the advocates of right rather

than expediency, scientifically and ethically.-I am, etc.,WILLIAmr HITCitSIAN, M.D.

Liverpool, August 1875.MR. WILLIAiS.-Dr. Thomas Mayo, a former President of the College of Physi-

cians, was the brother of Mr. Herbert Mayo of King's College.

COIRESPONDENTS are particularly requested by the Editor to observethat communications relating to Advertisements, changes of address,and other business matters, should be addressed to Mr. FrancisFowke, General Secretary and Manager, at the Journal Office, 36,Great Queen Street, WV. C., and not to the Editor.

MRDICAL PRACTICE IN AMERICA.StIR-In reply to the inquiries of H. G. 1). in your isIuC of July 24th, I may informhim (0) that neither legislators nor patients in tile United States trouble themselvesabout the source of a. niedial nian's diploma, there being no system of registration,1o1r .oiy difference recognised between the oegtees of rtgular. homecopathic,

clCetic", or alay otther schools. Nothing but the title of" Dr.", however, isknown to the Ame:ricail public; I.D. being the degree granted by all our col-leges, and no lescr qlualificatioln existing. (2) lhe itdical main's social statusi-. secoid to IloIIC other ; btit, as I have already hil.ttd, we have no distinction be-twetn pure physiciats or pute surgeons and general practitioners, the whole pro-fessioin standing on an equal " MI.D." footing. ! With thirty-odd medical schoolsturning out niany hundred graduates~cor annum, the profession is decidedly over-stocked in every scction of which 1 have knowledge, though, of course, here aselsewhere, " there is always room high up".-Yours, etc.,New York, August 4th, 1875. AN ArIuRICAN M.D.

BETA--We know nothing of "nciss' as a remedy for cancer: but our corre-spondncit may safely put it, duw as utterly useless.

At-Esar or SI>EmCnt IN AN INFANT APTKR A BLOW ON THE HEAD.SIR,- A few days ago a patient Lonstilted me for a skin-affection on her son, a fine

little boy four years and a half old, and told me the following about him. Whenlie was eighteen months old, he received a fall, from which lte had a contusion ofthe skin and a small tumour in the temporal region (left side). He gradually re-covered. Beforc the accident, he alas just commenicing to prattle a few simplemotiosyllables, but since then has riot been able to speak, and has scarcely evertried.

If any of your readers have met with a similar case, and can recommend any-thing to remedy the diisability, I n-ill be glad to know of it.-Yours truly,

llryninawr, Atigt1st x8th. 1875. B. J. GLISSAN, Physician, etc.

GicO.o(;lST.-Professor Clark of Cambridge is a son of the gentleman you mention.The Bishop of Lhichestcr, when dining one tlay with George IV at Brighton, wasasked by his Majesty if theic was not more than cie of his name at the Univcr-sity of Canibridge. " Yes', said his Grace, " there were three-viz., Stone-Clark,Professor of Al ineralogy ; Tone-Clark, Professor of Music aind Bone-Clark, Pro-fessor of Anatomy."

THis PARLIAMENTAity BILLS Cosistiir-Trs OF THE BRITISH MEDICALASsocIATION.

SIR,-At my recent visit to Edinburgh, I was mitch pleased to see the rapid growthmade by the Associaitiont dtiring the last few years, It has become an institutionof great nmational importance, exercising a powerftil intluience on the legislature ofthis country, which has and will hereafter be attended with the most beneficialrestilts. There was a subject which had beets taken up with advantace by theParliametitary Bills Committee-viz., the superannuation grants to union sur-geons, to which I wish to direct attention. Much good has followed their effortsin this matter: I therefore suggest that they shall carry out the good work theyhave began, and get the allowances to gaol surgeons put on a more satisfactorybasis. The present Prison Regulation Act acknowledges the justice of such grantsbeing niade, blt does not enforce it. The section (i5) states that on a recom-mendation of the visiting j uistices, a grant " may" be allowed, etc. ; but when re-commendations have been made by the visiting justices, the allowances have notalways been granted at the sessions or by the municipal corporate bodies-indeed,in some instances they have been refused. I wotild stiggest that in the nextPrison Regulation Bill the word " shall" be substituted for " may", which will dojustice to medical men who have become incapacitated by lonig service or con-firmed sickness, and will be equally satisfactory to visiting Justices.

I hope yowl will see the reasonabletiess of the above suggestion, and induce theParliamentary Bills Committee to use their efforts in getting it carried out.-Iam, etc., A GAOL SURGEON.

*et Our correspondent's letter will be brought under the notice of the Com-mittee. The superannatiaion of Poor-law medical officers is, however, at presentalso permissive, and not compulsory. The Panliameiitary Bills Committee haveunder notice certain palpable grievances of the medical officers of the ConvictService.

DR. E. HOLLAND has favoured us with a smoothly written, pleasantly versified,account of a trip which he made " From Waverley to Balloch Strand" after theEdiaburgis meeting of the British Medical Association.

"Whltein Scotland's capital--their labours o'er-Bid Ausculapians, fatigued, exploreThe matchless beauties of her darling land."

WVe are much obliged to him for the opportunity of reading his MS., and if hewill inform us where to send it, it shall be restored to him.

DR. E. SLADE-KING (Ilfracombe).-x. We believe that Reynolds's System of Mcdicine will be found the most useful and complete work of the kind at resent available for your purpose. 2. The Cambridge Examinations in StateMedicine arereadily available to all p X sons who.e names arc on the Medical Register, and areat least twenty-four years of age. The Examination is divided into two parts.The first comprises physics; the principles of chemistry, with analysis of air andwater, microscopical aiid chemical ; the laws of heat; the principles of pneuma-tics, hydrostatics, and hydraulics, with especial reference to ventilation, water-supply, drainage, construction of dwellings, and sanitary engineering generally.The second part comprises the laws of the realm relating to public health ; sani-tary statistics; origin, propagation, pathology, and prevention of epidemic and in-fectious diseases; effects of overcrowding, vitiated air, impure water, and bad orinsufficient food; unhealthy occupations, anid the diseases to which they giverise ; water-supply, and disposal of sewage and refuse nuisances injurious to health;distribution of diseases within the United Kingdom, and the cffects of soil, season,and climate. We would advise our correspondent to write to Professor Liveing,University of Cambridge, for fuller information; but we can recommend, amongstother works, Parkes's Manual ofiygiene, Mr. Simon's Reports to the MedicalDrhantme ofa/the Privy Council, Hart's or Wilson's Manmal ofPfebiic HealthEassie's Sanitary Arrangemnents for Dwellings. Professor Corfield's Lectures,and Dr. Meymott Tidy on the Adulteration of Food. Mr. Wanklyn's manualsof analysis arc very valuable. Any bookseller can procure these work.

3193

THE BRITISH MEDICAL 7OURNAL.

NOTICE TO AnvERTISERS..-Advertisements for insertion in theBRITISH rMEDICAL JOURNAL, should be forwarded direct to the PublishingOffice, 36, Great Queen Street, W. C., addressed to Mr. FOWKE, nolater than Thursday, twelve o'clock.

OFFENsivE DISCHARGE FROs, CANCRR.SIR,-In reply to Triceps, there is nothing in my experience to equal the commonaqua picis, once belonging to the Dublin Phartsacopxia. For his purpose, lethim put a teaspoonful or two of good Norway tar into a large wine-bottle, havingpreviously filled it threc-fourths full of boiling or very hot water. Shake well fora few minutes, and it is ready for use. When the water is exhausted, it may berenewed by adding fresh boiling or hot water, which may be repeated as often asthe original tar serves to impregnate the fresh water strongly with its peculiarodour. It may be applied on pledgets of charpie or muslin-the thinner the fabricthe better-and it may be renewed by-means of a sponge, simply squeezing thesponge over the offensive surfaces ; or, still better, diffuse it over the surface ofthe cloth or of the diseased structure by means of an odorator. The patient cando this herself; all that is necessary is to attach an India-rubber tube-the sameas an infant's feeding-bottle-which will reach the mouth of the patient. She will,by the use of this simple and inexpensive wash, keep herself and the atmosphereof the room perfectly sweet: indeed, the power of tar or oil of tar as a deodorantis simply next to magic, and is not to be equalled by any of the advertised spe-cifics. It would not pay to advertise it; but I have used it now in carcinomauteri and other external cancers for the past twelve or thirteen years, by injectionor as above directed, and I pronounce it unsurpassable.

Messrs. Symes and Co., of T4, Hardman Street, in this town, have lately pre-pared for mea very elegant substitute ; it is the best oil of tar rendered miscible inhot or cold water. Ten or fifteen drops or more to a int of water make an ex-cellent deodorant lotion, wash. injection, or enema. Kn the latter case, it is per-fectly invaluable in wards of hospitals, as the stool is quite deodorised before itsexit, and the ward is thereby kept sweet.Symes and Co. prepare a deodorant powder, which some prepare; it is chiefly

composed by wvhiting and oleurm picis, very dilute.-1 am, etc.,Liverpool, August 28th, 1875. THO'IIOAS SKINNER. M.D.P.S.-As a lotion or enema, it is to be used cold or tepid. If it in any way

smart, dilute with water.

SIR,-In answer to your correspondent Triceps, I beg to state that I have had un-der my care a lady with epithelioma of the right breast for seven vears, that it atone time assumed very formidable dimensions, and the odoutr was intolerable: butby dressing it inl the following manner it has lessened in size, and, excepting whensloughing takes place, emits little or no effluvium. The part is washed with warmwater, in which a few grains of permanganate of potash are dissolved, arsd driedwith a soft rag. The strongest liquor carbolis detergens is applied with a camel-hair brush; it is then covered wiLh unguentum carbolis detergens, spread uponlint.-Yours obediently, FRANt:is ToULMIN.Upper Clapton, August 31st, 1875.

SIR,-Triceps will find that a weak solution of suilphurous acid will effectually re-move all the offensive smell from the discharge from the cancerous breast.-I am,sir, yours truly, E. O., F.R.C.S.

DR. DAvY.-Glycerine was discovered by Scheele, and the late Mr. Startin is statedto have been the first to use it therapeutically.

K.-If you will send the MISS., we shall be enabled to give yosi an answer.

CArsIcuhs IN DELIRIUM POTU.SIR,-In answer to Dr. Hadley's question as to what is the mode of administering

capsicum in deliriam ,e'otu, I would say that I have found that the best way todo so is in the form of pills ; about four grains of the best powdered capsicummade up into a pill, with extract of gentian. Orse pill to be taken every twohours? till quietude is obtained. The more I use this drug in such cases, the moream I impressed with its great usefulness.-I am, yours faithfully,Buckingham, August 2ast, r875. L'HEUREUX BLENKARNE.

SIt,-Dr. Hadley will find ten minims of the tincture of capsicuim taken in an ounceand a half of water before meals, or whenever depression or craving for alcoholarise, very useful. The powder may also be given in twenty or thirty grain doses,made up into a bolus with honey, and the dose repeated in three hours if it fail toprocture sleep.-Yours faithfully. HENRY M. JAY.Chippenham, August 23rd, 1875.

A MILTROPOlITAN TEACHER. - It is quite true that Mr. Hancock has sat forthe last time as a member of the Court of Examiners of the College of Surgeons." Honest and true Hancock", says an esteemed correspondent, a teacher and suir-geon to one of osir large hospitals, " a man so thoroughly trustworthy". WVc be-lieve he will for the present retain his seat at the Council.

THnE PROBAOILITY OF A SEcoNi ATTACK OF MEASLES.SIR,-In your impressions of June 5th, s2th, and t9th, recently arrived here, I haveread some letters pertaining to the above subject. Permit me to record a fcwfacts which ocecurred in my own family, which will tend to show that a second oreven third attack in life is by no means imposs'ble. In the early part of I867, mywife was attacked with well marked measles for the third time in my knowledge.The third attack occurred two days after her confiniement. Her baby had measlessharply, as also our son, then aged about two years. At that time measles wereepidemic in the town we were living in. In the early part of 1872, measles wereagain prevalent in the town we were living, and both my children had anotherwell marked attack of measles. They are both at school now, my son going to apublic school next year (owing to my absence from England, and the fact of theirmother's death), and I shall view with anxiety the possibility of their exposure toa third attack.One more remark with regard to the outbreak in i867. Although, as X said,

measles were prevalent in the town we were residing in, I may mention that ini866, during the early months of her pregnancy, my wife, with a mother's care,nursed another of her children, who succumbed to measles. She was nccr, asfar as I could ascertain, exposed to any contagion subsequently. Could the dis-ease have lain dormant for so long a period as nearly seven months in her preg.nant condition? This is a point which may be worthy of consideration. -Enclos-ing my card, I beg to remain, sir, yours truly, F.R.C.S.Eng., R.N.

Esquimalt, British Canajda, August 5sth, 1875.DR. O'FLAHERTV.-During the collegiate year ending Ath of April last, 45 candi-

dates were admitted Fellows of the Irish College of Surgeons, 124 gentlemen re-ccived letters testimonial, and 22 licentiates obtained the diploma in midwifery.

NOTICES of Births, Deaths, Marriages, and Appointments, intended forinsertion in the BRITISH MEDICAL JOURNAL, should arrive at theOffice not later than 10 A. M. on Thursday.

H. L. AND A MtKMIs.R.-The Library and Museum of the College of Surgeons willbe closed as usual during the month of September. The works of John of Ardernand Gaddesden are in the Library. Write to MIr. Chatto, the obligiig librarian,who will give you the information.

T. C., ADELAIDE.-The man is an arrant quack." Hold thy hand, health's dear maintainer

Life, perchance, may burn the stronger;Ilaving substance lo maintain her,She, untouched, may last the longer.When the artist goes aboutTo redress her flume, I dosbtOftentimes he Snuffs it out."-QUAsRL.-S.

GLYCERINE AND BORAX.SIR,-I should think the chemicals used by your correspondeut in his mixture musthave been inipure, for, in cases of aphthte, I am often in the habit of prescribing,with great success, borax and glycerine (3ij c. Ij), but have never observed anysuch explosion whilst dispensing them. -Yours, etc., Ml. R. C. P. Edin.August 23rd, 1875.

MR. ASHtIIRTON THosMPsoN.-We fear we should not have at command for sometime the space required.

A. R. A.-Professor John Marshall, F.R.S., a member of the Council and Court ofExaminers of the College of Surgeons, was elected Professor of Anatomy to theRoyal Academy in 1873, in the vacancy occasioned by the death of ProfessorPartridge, F. R. S.

We are indebted to correspondents for the following periodicals, containing news.reports, and other matters of medical interest:-The Bristol Daily Post; TheDaily Bristol Times and Mirror; The Derby and Chesterfield Reporter; TheLincolnshire Herald; The Glasgow Herald; The Sunderland Dail Echo; TheCarnarvon and Denbigh Herald; The Manchester Guardian; Y'the EuropeanReview; The Hackney and Kingsland Gazette; The Worcesterslhire Chronicle;The Birmingham Daily Post; The Brighton Daily News; The Sussex DailyNews; The Glasgow Herald; The Cork Examiner: The Scotsman; The CorkDaily Herald ; The Southampton Times and Hampshire Express; Trhe Hamp-shire Advertiser; The Birmingham Morning News; The Chester Courant; TheMetropolitan; The Live-Stock Journal; The Shield; The Grocer: The Shippingand mercantile Gazette; The Advertiser; The Islington Gazette; The PenrithObserver; The Hastings and St. Leonard's Gazette; The Ilklcy Free Press; TheLeicester Daily Post; etc.

COMMUNICATIONS, LETTERS, ETc., have been received from:-Dr. George Johnson, London; Dr. Kelly, Taunton; Dr. Atkinson, Kingston.on-Thames; Mr. K. P. Leech, Woolpit; Mr. E. R. Morgan, Ncath; Mr. JohnBuckley, R.N.; Mr. Tallack, London; Dr. Underhill, Edinburgh; Our ParisCorrespondent; Dr. Griflfiths, Sheffield; Mr. Taylor, Bocking; Dr. H. Swete,Droitwich; Dr. J. H. Aveling, London; Dr. E. Holland, London; Dr. JosephRogers, London; The Warden, Queen's College, Birmingham; The Registrar-General of Ireland; Dr. W. Kebbell, Brighton; The Secretary of Apothecarics'Hall; Mr. T. MI. Stone, London; The Registrar-General of England; Mr. S.W. North, York; Mr. W. E. Curtis, Canterbury: Our Glasgow Correspondent;Mir. Eassic, London; Dr. J. Milner Fothergill, London; Dr. Philipson, New-castle-on-Tyne; Dr. Paine, Strosid; Our Dublin Correspondent; Mr. E. Chap-man, Oxford; eir. Edmund Owen, Loudon; Mr. T. N. Lucas, London; Mr.Eastes, London; Mr. Francis Toulmin, Clapton; Mr. Lund, Manchester; Mr.

J. C. Leach, Sturniinster Newton; Stirgeon-Major Oliver, Canada; Sir DuncanGibb, London; Dr. J. Crichtois lirowne, Wakefield; MIr. F. NV. Lowndes,Liverpool; Dr. A. Morison, London; Dr. Cleland, Galway; Dr. J. W. Lang-more, London; Dr. Russell, Glasgow; Mr. G. H. Fosbrook, Stratford-on-Avon Mr. R. H. S. Carpenter, London; Mr. T. Worth, Nottingham; Dr. C.Bell Taylor, Nottingham; Mr. Otho Galgey, St. Vincent; Mlr. A. Thomson,London; Dr. J. C. Morgan, London; Mr. L. H. Jones, London; AMr. E. W.Thurston, Aslsford ; Dr. A. Collie, lHonrerton; Mir. G. R. Cundall, London;MIr. T. Ramsay, Winchester; Air. J. Garner, Birnsinlgham; lDr. Oppenheim,London; Dr. J. Sawyer, Birmingham; Dr. WV. Hitchman, Liverpool; Mr. W.B. Kendall, 1idsgrove; Mr. J. Brovn, Sheffield; Air. E. Bellamy, London;Dr. Bryant, Northamnptons; Mr. J. Buckenham, Cambridge: MIr. Kenwosthy,Bowden; Dr. J. W. Young, Dublin; Dr. R. Liveing, London; Dr. Wallace,Turriff; Mr. A. James, Liverpool;.Mr. C. R. Rsy, Arbroathil Dr. A. Sheen,Cardiff; Mr. E. G. Carey, Manchester; Dr. IBeverley, Norwich; Dr. Shuttle.worth, Lancaster; Dr. J. A. Angus, Newcastle-on-Tyne; Dr. C. Harrison, Lin-coln; Mr. Hsisband, York; Mr. J. H. Stowers, Shrewsbtiry; Mfr. R. M. Gunn,Golspie ; Mr. C. H. Fassson, Edinburgh; Mr. C. Valentine, Brechin; Mir. J.Deans, Sunderland; Mr. R. M. Craven, Southport; Mr. J. Pollard, Torquay;Mr. C. K Thoinas, London; Dr. R. Collum, Surbiton; etc.

BOOKS, ETC., RECEIVED.

A Report on the Hygiene of the United States Army, with Descriptions of MilitaryPosts. By J. S. Billings. Washington: 1875.

A Second Report to the Chairman and Members of the Comb'ned Sanitary Aitho-rities of Oxfordshirc on the Sanitary Codition of their Districts, from March25th to December 3ist, 1574. By G. WV. Child. London : Longman, Green,and Co. 1875.

The Royal Tiger of Bengal: his Life and Death. By J. Favrci, M.I., F.G.S.London: J. and A. Churchill. 1875.

A Practical Treatise on Diseases of the Eye. By R. B. Carter, F.R.C.S. London:Macmillan and Co. 1875.

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(Sept-4,1875-