saliva test
TRANSCRIPT
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Saliva testSaliva testtinny rasjadtinny rasjad
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Salivary glands - AnatomySalivary glands - Anatomy
Minor salivary glandsMinor salivary glandsHundreds throughoutHundreds throughout
mouthmouth
Major salivary glands (3Major salivary glands (3
on each side of face)on each side of face)Parotid Gland (chee)Parotid Gland (chee)
Su!mandi!ular glandSu!mandi!ular gland
(under angle of the ja")(under angle of the ja")
Su!lingual gland (underSu!lingual gland (under
tongue)tongue)
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Physiology and #unctionPhysiology and #unction
Saliva functionSaliva function$ontrols oral %H$ontrols oral %H
Assists "ith food intaeAssists "ith food intae
&u!ricates food !olus&u!ricates food !olus
$ontains amylase for car!ohydrate$ontains amylase for car!ohydrate
digestiondigestion
Mouth cleansing and oral hygieneMouth cleansing and oral hygiene
Saliva limits oral %athogen gro"thSaliva limits oral %athogen gro"th 'educes oral odor (halitosis)'educes oral odor (halitosis)
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Saliva contentSaliva content
ater *+,ater *+,
rganic com%ounds mucin* amylase*rganic com%ounds mucin* amylase*
lyso.ym* immunoglo!ulin Alyso.ym* immunoglo!ulin AAnorganic com%ounds H$Anorganic com%ounds H$3-3-* /* $l* 0a** /* $l* 0a*
$a* %hos%hates and others1$a* %hos%hates and others1
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A%licationA%lication
Molecular DiagnosticMolecular Diagnostic
2etection of 20A und '0A "ith molecular !iological2etection of 20A und '0A "ith molecular !iological
methodsmethods
- Head nec cancer- Head nec cancer cancer diagnosis for health carecancer diagnosis for health care
- $linical diagnostic of infections and %eriodontitis- $linical diagnostic of infections and %eriodontitis
direct detection of viral and !acterial %athogensdirect detection of viral and !acterial %athogens
Drug Detection (Drugs of Abuse)Drug Detection (Drugs of Abuse)
4he detection of narcotics e1g1 cocaine*4he detection of narcotics e1g1 cocaine*
am%hetamines and %sychotro%icam%hetamines and %sychotro%ic
current drug consumption.current drug consumption.
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A%licationA%lication
Hormones and EnzymesHormones and Enzymes
2etermination of steroid hormones* e1g12etermination of steroid hormones* e1g1
cortisol as "ell as !iogenic amines ascortisol as "ell as !iogenic amines as
melatonin from saliva can give information onmelatonin from saliva can give information on
a %erson5s current hormone statusa %erson5s current hormone status
-amylase-amylase is a %arameter to identify stressis a %arameter to identify stress
and also used for authentification of saliva inand also used for authentification of saliva inthe drug screening area1the drug screening area1
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A%licationA%lication
Clinical cemistry parametersClinical cemistry parameters 6lectrolytes as /7* Mg87* $a87* P+*6lectrolytes as /7* Mg87* $a87* P+*
li%ids as H2&*li%ids as H2&*
salivar %roteins meta!olites as al!umin*salivar %roteins meta!olites as al!umin*total %rotein and creatinine sho" goodtotal %rotein and creatinine sho" good
correlation of saliva 9 serumcorrelation of saliva 9 serum
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4esting of saliva %roduction4esting of saliva %roduction
:nstimulated %roduction collection of saliva:nstimulated %roduction collection of saliva
into container during ;< mininto container during ;< min
Stimulated %roduction collection of salivaStimulated %roduction collection of saliva
during ;< min of che"ing %arafine gumduring ;< min of che"ing %arafine gumMeasuring of !oth amounts during 8=;< minMeasuring of !oth amounts during 8=;< min
0ormal levels9 greater than >-;? ml0ormal levels9 greater than >-;? ml
Pathologic levels9 under > mlPathologic levels9 under > ml
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@erostomia@erostomia
DefinitionDefinition
2ecreased saliva %roduction2ecreased saliva %roduction
!ysiology" #ali$a plays $ital role in!ysiology" #ali$a plays $ital role indental ealtdental ealt
'e-minerali.es enamel'e-minerali.es enamel
uffers cariogenic acidsuffers cariogenic acids
'emoves food residue'emoves food residue
Bnhi!its !acterial gro"thBnhi!its !acterial gro"th
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Causes of %erostomiaCauses of %erostomia
Medications (anticholinergic affect)Medications (anticholinergic affect)
4ricyclic Antide%ressant4ricyclic Antide%ressantss
Antis%asmodicsAntis%asmodics
0eurole%tic0eurole%ticss
MA inhi!itorMA inhi!itorss
Anti%arinsonian agentsAnti%arinsonian agents
&ithium&ithium
$entral Adrenergic Agonist$entral Adrenergic Agonists (antihy%ertensives)s (antihy%ertensives)
2iuretics2iuretics
2econgestant2econgestantss
AntihistamineAntihistaminess
ronchodilatorronchodilatorss
http://www.fpnotebook.com/PSY193.htmhttp://www.fpnotebook.com/PSY193.htmhttp://www.fpnotebook.com/PSY205.htmhttp://www.fpnotebook.com/PSY205.htmhttp://www.fpnotebook.com/PSY187.htmhttp://www.fpnotebook.com/PSY187.htmhttp://www.fpnotebook.com/PSY171.htmhttp://www.fpnotebook.com/PSY171.htmhttp://www.fpnotebook.com/CV217.htmhttp://www.fpnotebook.com/CV217.htmhttp://www.fpnotebook.com/CV232.htmhttp://www.fpnotebook.com/CV232.htmhttp://www.fpnotebook.com/ENT166.htmhttp://www.fpnotebook.com/ENT166.htmhttp://www.fpnotebook.com/ENT144.htmhttp://www.fpnotebook.com/ENT144.htmhttp://www.fpnotebook.com/LUN127.htmhttp://www.fpnotebook.com/LUN127.htmhttp://www.fpnotebook.com/LUN127.htmhttp://www.fpnotebook.com/ENT144.htmhttp://www.fpnotebook.com/ENT166.htmhttp://www.fpnotebook.com/CV232.htmhttp://www.fpnotebook.com/CV217.htmhttp://www.fpnotebook.com/PSY171.htmhttp://www.fpnotebook.com/PSY187.htmhttp://www.fpnotebook.com/PSY205.htmhttp://www.fpnotebook.com/PSY193.htm -
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ther causesther causes
'adiation thera%y to head and nec'adiation thera%y to head and nec
Salivary GlandSalivary Glandsurgerysurgery
Sjogren5s SyndromeSjogren5s Syndrome
AmyloidosisAmyloidosisHuman Bmmunodeficiency CirusHuman Bmmunodeficiency Cirus((HBC BnfectionHBC Bnfection))
2ia!etes Mellitus2ia!etes Mellitus
Major 2e%ressionMajor 2e%ression
Granulomatous 2iseaseGranulomatous 2isease SarcoidosisSarcoidosis
4u!erculosis4u!erculosis
&e%rosy&e%rosy
http://www.fpnotebook.com/ENT58.htmhttp://www.fpnotebook.com/ENT58.htmhttp://www.fpnotebook.com/RHE26.htmhttp://www.fpnotebook.com/RHE26.htmhttp://www.fpnotebook.com/RHE16.htmhttp://www.fpnotebook.com/RHE16.htmhttp://www.fpnotebook.com/HIV11.htmhttp://www.fpnotebook.com/HIV11.htmhttp://www.fpnotebook.com/HIV11.htmhttp://www.fpnotebook.com/HIV11.htmhttp://www.fpnotebook.com/END11.htmhttp://www.fpnotebook.com/END11.htmhttp://www.fpnotebook.com/PSY63.htmhttp://www.fpnotebook.com/PSY63.htmhttp://www.fpnotebook.com/LUN93.htmhttp://www.fpnotebook.com/LUN93.htmhttp://www.fpnotebook.com/LUN188.htmhttp://www.fpnotebook.com/LUN188.htmhttp://www.fpnotebook.com/ID3.htmhttp://www.fpnotebook.com/ID3.htmhttp://www.fpnotebook.com/ID3.htmhttp://www.fpnotebook.com/LUN188.htmhttp://www.fpnotebook.com/LUN93.htmhttp://www.fpnotebook.com/PSY63.htmhttp://www.fpnotebook.com/END11.htmhttp://www.fpnotebook.com/HIV11.htmhttp://www.fpnotebook.com/HIV11.htmhttp://www.fpnotebook.com/RHE16.htmhttp://www.fpnotebook.com/RHE26.htmhttp://www.fpnotebook.com/ENT58.htm -
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Stomatitis and locali.ed oral lesionsStomatitis and locali.ed oral lesionsA%hthous :lcersA%hthous :lcers
ral chemical !urnsral chemical !urns
ral su%%urative lesionsral su%%urative lesions
Alveolar a!scessAlveolar a!scess
6%ulis6%ulis ral infectious &esionsral infectious &esions
2ental $aries2ental $aries
2i%htheria2i%htheria
Sy%hilisSy%hilis
4u!erculosis4u!erculosisSmall Po=Small Po=
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Acute viral sialadenitisAcute viral sialadenitis
Parotitis acutaParotitis acuta
Paramy=ovirusParamy=ovirus
0eurotro%hic effect n1CBBB0eurotro%hic effect n1CBBBAffection of gonadal tissues* %ancreas*Affection of gonadal tissues* %ancreas*
central nervous systEmcentral nervous systEm
Bncu!ation9 ;> daysBncu!ation9 ;> dayshole life immunityhole life immunity
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Acute !acterial sialadenitisAcute !acterial sialadenitis
Ascendent ductal infectionAscendent ductal infection
2ehydratation* dia!etes* renal diseases*2ehydratation* dia!etes* renal diseases*
"rong dental hygiene* inflammation in"rong dental hygiene* inflammation in
mouth and %haryn=mouth and %haryn=
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$hronic !acterial %arotitis$hronic !acterial %arotitis
Predis%osition ectasy of salivary ducts Predis%osition ectasy of salivary ducts
congenital* %ostinfectious* o!structive*congenital* %ostinfectious* o!structive*
immuno%atologicalimmuno%atological
Sialogra%hySialogra%hy
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SialolithiasisSialolithiasis
Stones com%osed of $a salts often o!structStones com%osed of $a salts often o!struct
salivary glands* causing %ain* s"elling* andsalivary glands* causing %ain* s"elling* and
sometimes infection1 2iagnosis is made clinicallysometimes infection1 2iagnosis is made clinically
or "ith $4* ultrasound* or sialogram1 4reatmentor "ith $4* ultrasound* or sialogram1 4reatmentinvolves stone e=%ression "ith saliva stimulants*involves stone e=%ression "ith saliva stimulants*
manual mani%ulation* a %ro!e* or surgery1manual mani%ulation* a %ro!e* or surgery1
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