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Curriculum Vitae SEPTEMBER2015StephenCClark BMedSci(Hons), BM, BS, DM, AMRAeS, MInstLM, FFSTEd, FRCS(C-Th)

Professor of Cardiothoracic Surgery & Cardiopulmonary Transplantation Department of Applied Science Faculty of Health & Life Sciences University of Northumbria

Consultant Cardiothoracic & Cardiopulmonary Transplant Surgeon Director of Cardiopulmonary Transplantation Regional Cardiothoracic Centre Newcastle upon Tyne Hospitals NHS Trust Associate Clinical Lecturer Institute of Cellular Medicine University of Newcastle

2 CURRICULUMVITAE–SCCLARK

Table of Contents PERSONAL DETAILS 3

QUALIFICATIONS 4

PRIZES, AWARDS & GRANTS 5

SUMMARY OF POSTS HELD 6

SPECIALISTTRAININGINCARDIOTHORACICSURGERY 6BASICSURGICALTRAINING 7

TRAINING UNDERTAKEN ABROAD 8

RESEARCH & PUBLICATIONS 9

THESES 9PAPERS&PUBLISHEDABSTRACTS 10PUBLISHEDLETTERS 26BOOKCHAPTERS 30MISCELLANEOUSPUBLICATIONS 30

PRESENTATIONS & INVITED LECTURES 31

INVITED CHAIRMANSHIPS 55

ACADEMIC EXPERIENCE 59RESEARCH 59ACADEMICACTIVITYFORLEARNEDSOCIETIES 60PROFESSIONALEXAMINATIONS 62EDUCATIONALROLES 62MISCELLANEOUSACADEMICACTIVITY 64

MANAGERIAL & LEADERSHIP EXPERIENCE 66

WITHINTHETRUST 66FORTHENATIONALHEALTHSERVICE 67

INNOVATION 71

SUB-SPECIALTY SPECIALISED SKILLS 71

MEDIA WORK 72

PROFESSIONAL COURSES ATTENDED 73

SOCIETY MEMBERSHIP 74

CURRICULUMVITAE–SCCLARK 3

PERSONAL DETAILS

NAME Stephen Charles CLARK DATE OF BIRTH October 1965 ADDRESS NATIONALITY British GMC NUMBER 3406881 ACCREDITATION DATE 29 February 2000 DATE OF APPOINTMENT 1 December 2000


QUALIFICATIONS

Bachelor of Medical Science FIRST CLASS HONOURS University of Nottingham (July 1987)

Bachelor of Medicine, Bachelor of Surgery WITH COMMENDATION University of Nottingham (July 1989)

Fellowship of the Royal College of Surgeons of England Applied Basic Sciences Section (January 1991)

Diploma of Fellow of the Royal College of Surgeons of England Clinical Surgery in General Section (May 1993)

Doctorate of Medicine University of Nottingham

(July 1999)

Intercollegiate Specialty Examination in Cardiothoracic Surgery (October 1999)


PRIZES, AWARDS & GRANTS

Nottingham University Exhibition 1986 University of Nottingham

Brian Sanderson Memorial Prize 1987 University of Nottingham

North of England Surgical Society Prize 1996

Geoffrey Giles Memorial Medal 1996 Fellows Surgical Research Fellowship 1996 The Royal College of Surgeons of England

David Cooper Prize 1998 Society of Cardiothoracic Surgeons of Great Britain and Ireland

Ethicon Foundation Fund Travelling Fellowship 1999 The Royal College of Surgeons of England

St. Jude Scholarship 1999 Society of Cardiothoracic Surgeons of Great Britain and Ireland Pump Priming Award 2001 The Royal College of Surgeons of England Research Grant Award (£10,000) 2001 Freeman Hospitals Special Trustees


SUMMARY OF POSTS HELD Specialist Training in Cardiothoracic Surgery

1st September 2000 to 1st December

2000

Senior Registrar and First Assistant

CARDIOTHORACIC SURGERY

Freeman Hospital, Newcastle Upon Tyne, UK

& University of

Newcastle upon Tyne, UK

Prof. J. H. Dark

Mr J R L Hamilton Mr C. J. Hilton Mr A. Hasan Mr J. Forty

Mr S. Ledingham

1st January 2000 to 31st August 2000

Fellow

CARDIAC SURGERY

Division of Cardiovascular Surgery,

Toronto General Hospital, Toronto, Ontario, Canada

Dr T.E. David Dr C. Feindel

Dr L. Mickleborough Dr C. Peniston

Dr R.J. Cusimano Dr A. Ralph-Edwards

Dr S. Brister Dr D. Weisel

Dr T. Yau

1st August 1995 to 31st December 1999

INCLUDING

Senior Registrar and First Assistant



& University of


Prof. J. H. Dark Mr J R L Hamilton

Mr M. Holden Mr C. J. Hilton Mr A. Hasan Mr J. Forty

Mr S. Ledingham

1st April 1996 to 31st March 1997

Research

Fellow

RESEARCH FELLOWSHIP Royal College of Surgeons of

England University of


Prof. J.H.Dark Dr J.Kirby

Prof. P. Flecknell

1st August 1994 to 31st July 1995

Surgical Transplant

Fellow (Registrar)

CARDIOPULMONARY TRANSPLANTATION


Prof. J. H. Dark

Mr J R L Hamilton Mr C. J. Hilton Mr A. Hasan Mr J. Forty

Mr S. Ledingham


Basic Surgical Training

1st February 1994 to 31st July 1994

Senior SHO

CARDIOTHORACIC

SURGERY Papworth Hospital, Cambridge

UK

Sir T.A.H. English

Mr J.Wallwork Mr S.R.Large Mr F.C.Wells

Mr S.A.M.Nashef

1st August 1993 to 31st January 1994

SHO


Bristol Royal Infirmary &

Frenchay Hospital, Bristol, UK

Prof. G. Angelini Mr J. A. Hutter Mr A.J. Bryan

Mr K. Jeyasingham Mr C. Forrester-Wood

1st February 1993 to

31st July 1993

SHO

GENERAL SURGERY

Bristol Royal Infirmary & Weston General Hospital, UK

Prof J. Farndon Prof. D. Alderson


SHO

ORTHOPAEDIC AND TRAUMA

SURGERY Leicester Royal Infirmary, UK

Mr R. Raymakers Mr J. Hoskinson

1st February 1992 to 31st July 1992

SHO

GENERAL AND VASCULAR

SURGERY Leicester Royal Infirmary, UK

Prof P.R.F. Bell Mr D. Ratliff


SHO


Brompton Hospital, UK

Prof. Sir M. Yacoub

Mr J. Pepper Mr P. Goldstraw

1st August 1990 to 31st July 1991

SHO

ACCIDENT AND EMERGENCY

Bristol Royal Infirmary, UK

Dr G. Hughes

ANATOMY DEMONSTRATOR

Bristol University, UK

Prof B.T. Pickering

1st February 1990 to

31st July 1990

JHO

GENERAL MEDICINE

Queens Medical Centre, Nottingham, UK

Prof P.C. Rubin

Prof C.J. Hawkey


JHO

GENERAL SURGERY

Queens Medical Centre, Nottingham, UK

Mr C.A.S. Pegg

Mr J. Doran


TRAINING UNDERTAKEN ABROAD Fellowship in Cardiac Surgery Division of Cardiovascular Surgery Toronto General Hospital Toronto, Ontario, Canada 1 January 2000 – 31 August 2000 Dr T. E. David, Dr C. Feindel, Dr L. Mickleborough, Dr D. Weisel, Dr R.J. Cusimano, Dr T.Ralph-Edwards, Dr C. Peniston, Dr S. Brister, Dr T. Yau Supported by the award of the St. Jude Scholarship by the Society of Cardiothoracic Surgeons of Great Britain and Ireland, and an Ethicon Fund award from the Royal College of Surgeons of England. This internationally renowned centre for cardiac and thoracic surgery undertakes over 2700 cardiac operations per year and also has an active cardiopulmonary transplant programme. The unit has 30 intensive care beds dedicated to cardiac surgical patients and has extensive facilities for both clinical and laboratory based research. It is optimised to deliver high quality care combined with maximal workload volume. The Division is particularly well known for its contributions to valve surgery in adults, in particular aortic root replacement (with sparing of the aortic valve) and mitral valve repair techniques. The unit is also at the forefront of developing off pump coronary artery surgery. Toronto hosts the largest cardiopulmonary transplant programme in the province of Ontario and has recently commenced a left ventricular assist device (LVAD) programme to bridge patients to transplant. Working in this prestigious institution allowed me to gain specialised experience of the following procedures : · Aortic valve replacement with stentless bioprostheses. · Aortic root replacement with aortic valve sparing (David I and II operations). · Mitral valve repair including experience of Goretex chordal reconstruction. · Off pump coronary artery surgery. · Left ventricular aneurysmectomy and arrythmia surgery. · Minimal access coronary artery and valve surgery. · Further training in all aspects of conventional coronary artery and valvular

surgery, including cardiac transplantation. In particular much experience was gained in coronary artery surgery in patients with severely impaired left ventricular function.

I am the first Fellow to be fully trained in off pump surgery in this unit and obtained a Certificate of Training from the institution. I also attended a training course at Massachusetts General Hospital, Boston, USA leading to certification by the equipment manufacturer. I was given responsibility for assessing acute admissions for cardiac surgery and regularly presented cases to the faculty at weekly departmental meetings (triage rounds). I was also able to participate in the academic activities of the unit, including research meetings and presentations and undertook a research project on coronary artery endarterectomy during my stay. A visit to the prestigious Cleveland Clinic, Ohio, USA for one week with Dr Delos Cosgrove was also a valuable addition to my time in North America.


RESEARCH & PUBLICATIONS

THESES

Bachelor of Medical Sciences Thesis entitled “Myocardial Hyperplasia in the Sudden Infant Death Syndrome”. Ventricular tissue from cot death victims and controls was investigated histologically and biochemically revealing numerous abnormalities of right ventricular tissue in cot death subjects.

I was awarded a First Class degree and the Brian Sanderson Memorial Prize for cardiovascular research by the University of Nottingham for this work.

Doctorate of Medicine Thesis entitled “ Methods of Attenuating

Pulmonary Reperfusion Injury after Single Lung Transplantation” was submitted to the University of Nottingham in October 1998 following a period of research developing a new porcine model of left single lung transplantation and reperfusion injury. The model was used to investigate physical and pharmacological methods of attenuating acute lung injury. The Fellows Surgical Research Fellowship was awarded by The Royal College of Surgeons of England to undertake this work, the results of which have been presented at numerous international meetings and published in a number of peer reviewed journals.

The DM degree was awarded in July 1999.

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CURRICULUMVITAE–SCCLARK

PAPERS & PUBLISHED ABSTRACTS Graff L.G., Clark S.C., Radford M.J. Critical Care by Emergency Physicians in American and English Hospitals. Archives of Emergency Medicine 1993;10:145-154. Clark S.C., Naylor A.R., Bell P.R.F. An Aid to Renal Preservation During Repair of Supra Renal Abdominal Aortic Aneurysms. European Journal of Vascular Surgery 1993;7:92. Clark S.C., Naylor A.R., Ratliff D.A., Bell P.R.F. Access to Convalescent Beds in Vascular Surgery. The British Journal of Surgery 1993;80:186. Clark S.C. “Do It Yourself“ Surgical Rotations. Surgery 1994;12:1- 2. Clark S.C., Norton S., Ridley P., Jeyasingham K. Spontaneous Pneumomediastinum. Journal of Accident and Emergency Medicine 1994;11:253-254. Naylor A.R., Clark S.C., London N., Sayers R., Macpherson S., Barry W., Bell P.R.F. Treatment of Major Aortic Graft Infection : Preliminary Experience with Total Graft Excision and In Situ Replacement with a Rifampicin Bonded Prosthesis. European Journal of Vascular Surgery 1995;9:252-256. Clark S.C., Dark J.H. Single Lung Transplantation Surgery 1995;13:241-245. Levine A.J., Clark S.C., Forty J. Cardiac Transplantation. Hospital Update 1996;22(9):386-391. Clark S.C., Levine A.J., Dark J.H. Lung and Heart-Lung Transplantation Hospital Update 1996;22(6):218-224. Clark S.C., Jones M.W., Chaudray R.R., Smith E. Bilateral Patella Tendon Rupture Secondary to Repeated Local Steroid Injections. Journal of Accident and Emergency Medicine 1995;12:300-301 Clark S.C., Norton S., Ridley P., Jeyasingham K


Epiphrenic Diverticulum - An Unusual Presentation & Review. Annals of the Royal College of Surgeons of England 1995;77:342-345. Clark S.C., Levine A.J., Hasan A., Hilton C.J., Forty J., Dark J.H. Vascular Complications of Lung Transplantation. Annals of Thoracic Surgery 1996;61:1079-1082. Clark S.C., Dark J.H., Kirby J.A. An Assay of Neutrophil Adhesion to Fibronectin and its Attenuation by Pentoxifylline and Nitric Oxide. Biochemical Society Transactions 1997;25:199. Clark S.C., Shenton B., Dark J.H., Kirby J.A An Assay of Neutrophil Adhesion to Fibronectin and its Attenuation by Pentoxifylline and Nitric Oxide (Abstract). Immunology 1996;Vol 89, Suppl. 1:40. Briffa N.P., Clark S.C., Kugan G., Coulden R., Wallwork J., Nashef S.A.M Surgical Angioplasty of the Left Main Coronary Artery : Follow up with Magnetic Resonance Imaging. Annals of Thoracic Surgery 1996;62: 550-552. Clark S.C., Khanna R., Roughan J., Flecknell P.A., Dark J.H. Pentoxifylline and Pressure Control in Lung Reperfusion Injury (Abstract). Journal of Heart and Lung Transplantation 1997; 16:72. Clark S.C., Dark J.H., Kirby J.A. Neutrophil Transmigration : Modulation by Pentoxifylline and Nitric Oxide. Biochemical Society Transactions 1997;25:454. Norton S.A., Clark S.C., Sheehan A.L., Ibrahim N.B., Jeyasingham K. Solitary Fibrous Tumour of the Diaphragm. Journal of Cardiovascular Surgery 1997;38(6):685. Clark S.C., Sudarshan C. D., Ali S., Dark J.H., Kirby J.A. Interleukin 8 Expression after Pharmacological Attenuation of Pulmonary Reperfusion Injury (Abstract). Journal of Heart and Lung Transplantation 1998;17(1):101. Clark S.C., Sudarshan C.D., Flecknell P.A., Dark J.H. Pharmacological and Physiological Modulation of Reperfusion Injury after Lung Transplantation (Abstract). Journal of Heart and Lung Transplantation 1998;17(1):61.

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Clark S.C., Sudarshan C., Khanna R., Roughan J., Flecknell P.A., Dark J.H. Controlled Reperfusion and Pentoxifylline Modulate Reperfusion Injury after Single Lung Transplantation. Journal of Thoracic and Cardiovascular Surgery 1998;115:1335 Clark S.C. The Modulation of Reperfusion Injury after Single Lung Transplantation. The Royal College of Surgeons of England Research Report 1998. Clark S.C. Sudarshan C., Khanna R., Roughan J., Flecknell P.A., Dark J.H. A New Porcine Model of Reperfusion Injury after Lung Transplantation. Laboratory Animals 1999;33:135-142.

Clark S.C., Sudarshan C., Roughan J., Flecknell P.A., Dark J.H. Modulation of Reperfusion Injury after Pentoxifylline Single Lung Transplantation by Inositol Polyanions and SIN-1. Journal of Thoracic and Cardiovascular Surgery 1999;117(3):556-564. Clark S.C., Vitale N., Zacharias J., Forty J. The Effect of Low Molecular Weight Heparin (Fragmin) on Bleeding after Cardiac Surgery. Annals of Thoracic Surgery 2000;69:762-765.

Clark S.C. Ethicon Foundation Fund Travelling Fellowship Report. Annals of the Royal College of Surgeons of England (Suppl) 2001;83:315-317. Wallis J. P., Chapman C.E., Orr K.E., Clark S., Forty J.R. Effect of White Cell Reduction of Transfused Red Cells on Postoperative Infection Rates in Cardiac Surgery. Transfusion 2002;42:1127-1134. Wigfield C., Clark S.C. Football Yes, Surgery No. (Personal View) British Medical Journal 2002;324:1343. Vitale N., Clark S.C., Ramsden A., Lillo A., Hasan A., Hilton C.J., Holden M. P. Clinical and Haemodynamic Evaluation of Small Perimount Aortic Valves in Patients aged 75 Years or Older. Annals of Thoracic Surgery 2003;75:35-40. Rao J., Clark S.C., Ali S., Kirby J., Flecknell P.A., Dark J.H. Improvements in lung compliance after pulmonary transplantation: correlation with interleukin 8 expression. European Journal of Cardiothoracic Surgery 2003;23:497-502.


K.G. Perreas, G. Niranjan, S.C. Clark Automated proximal anastomosis for redo coronary artery bypass grafting through a lateral thoracotomy. Journal of Thoracic and Cardiovascular Surgery 2003;126:606-607. Clark S.C., Rao J.N., Flecknell P.A., Dark J. H. Pentoxifylline is as effective as leukocyte depletion for modulating pulmonary reperfusion injury. Journal of Thoracic and Cardiovascular Surgery 2003;126(6):2052-2057. Zacharias J., Clark S.C., Hamilton J.R.L.H., Dark J.H., Hasan A Unilateral pulmonary thromboendarterectomy for iatrogenic pulmonary hypertension in a ten year old. Journal of Thoracic and Cardiovascular Surgery 2003;126:1210-1211. Lord S., Clark S.C. Pacing the left ventricle through the coronary sinus in a patient with a prosthetic tricuspid valve replacement Heart 2003;89(12):1444 Reddy.S.L., Pillai J., Mitchell L., Naik S., Dark J.H., Hasan A., Ledingham S.J.M., Clark S.C. First report of No-React bovine internal mammary artery performance and patency Heart Surgery Forum 2004;1080:7(5) Ahmed I.M., Gupta A., Gould K., Clark S.C. A Fatal Fungus - Candida Famata Mediastinitis Annals of Thoracic Surgery 2005;80(2), 723-724 Jeyakanthan M., Abid Q., Pillay T., Clark S.C.,Dark J. H., Schueler S. Single centre experience with bronchial healing after lung transplantation: A review of 555 anastomoses Journal of Heart and Lung Transplantation 2005;24;2,Suppl; S56-57 Clark S. C. Leucocyte Filtration in Lung Transplantation Filtration 2005;1:31-33 Clark S. C. Lung Injury after Cardiopulmonary Bypass Perfusion 2006;21:225-228 T. A. Butt, J. D. Aitchison, P. A. Corris, J. Wardle, S. C. Clark, J. H. Dark Lung transplantation from deceased donors without pretreatment Journal of Heart and Lung Transplantation 2007;26 (2)

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Natarajan A., Samadian S., Clark S.C. Coronary Artery Bypass Surgery in Elderly People Post Graduate Medical Journal 2007;83:154-158 Shaaban H., Sharma H., Rao J., Clark S.C. A pulmonary artery false aneurysm after right middle lobectomy - a case report Journal of Medical Case Reports 2007;1(1);70 Botha P., Jeyakanthan M., Rao J, Fisher A.J., Prabhu M., Dark J.H., Clark S.C. Inhaled Nitric Oxide for Modulation of Ischaemia-Reperfusion Injury in Lung Transplantation Journal of Heart and Lung Transplantation 2007;26:1199-1205

Nyawo B., Shoab R.F., Evemy K., Clark S.C. Infective Endocarditis during Pregnancy Heart Surgery Forum 2007:10(6); 480-481 Nyawo B., Botha P., Pillay T., Clark S.C., Tocewicz K., Forty J., Hamilton J.R.L., Hill P., Hasan A. Clinical Experience with Assisted Venous Drainage Cardiopulmonary Bypass in Elective Cardiac Reoperations. Heart Surgery Forum 2008:11(1);21-23 C. Van De Wauwer, M. Villavicencio, N. Wrightson, T. Butt, S.C. Clark, T. Pillay, K. Tocewiczs, S. Ledingham, J. Forty, S. Schueler Non-Utilization of Donor Organs for Non Medical Reasons – Impact on Patients Waiting for Heart and Lung Transplantation The Journal of Heart and Lung Transplantation 2008; 27(2)2;tS223 Adwan H., Wigfield C. H., Clark S.C., Barnard S. Interventional Bronchoscopy for Benign Tracheobronchial Diseases under Cardiopulmonary Bypass Support Journal of Cardiothoracic Surgery 2008:3;27 Karamanou D., Bean S., Prabhu M., Walden H., Clark S., Corris P.A., Dark J.H The Effect of Ex Vivo Lung Perfusion on Proinflammatory and Anti-Inflammatory Cytokines in the Human Lung Thorax 2009;64(Suppl IV) A25 Pawale A., Chealikani G., Mitchell L., Clark S. C. Imaging modalities for Retrieval of a Migrated Coil from the Left Ventricle, after Pulmonary Arterio-Venous Malformation Embolisation Interactive Journal of Cardiovascular and Thoracic Surgery 2009;9:543-544


Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of The Royal College of Surgeons of England 2009;91(8):708-10 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of The Royal College of Surgeons of England 2009;91(7):613-6 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of The Royal College of Surgeons of England 2009;91(3):263-5 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Surgeons News (Royal College of Surgeons of Edinburgh) 2009;8(October):38-9 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Surgeons News (Royal College of Surgeons of Edinburgh) 2009;8(April):36-37 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Newsletter of the Association of Surgeons of Great Britain & Ireland 2009;28 (Dec);62-63 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Newsletter of the Association of Surgeons of Great Britain & Ireland 2009;27 (Sep);52-54 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Newsletter of the Association of Surgeons of Great Britain & Ireland 2009;26 (Jul);58-59

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Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Newsletter of the Association of Surgeons of Great Britain & Ireland 2009;25 (Mar);50-51 2008 Azribi F., Razak R.A.,Bough G., Lee D., Rowe D., Bown N., Dildey P., Clark S.C., Plummer R. Extraosseous Pericardial Ewings Sarcoma Journal of Clinical Oncology 2010;28(4);48-50 Burdett C.L., Critchley R., Black F., Barnard S., Clark S.C., Corris P.A., Gould K.F., Butt T., Dark J.H. Invasive Biopsy is Effective and Useful after Lung Transplant Journal of Heart and Lung Transplantation 2010;29(7);759-763 Shanmuganathan S., Butt T., Clark S. C. Outcome of Lung Graft Volume Reduction for Oversized Donors during Pulmonary Transplantation Journal of Heart and Lung Transplantation 2010;29:2 Suppl: S135 Karamanou D., Walden H., Bean S., Prabhu M., Clark S. C. Simpson A., Corris P., Dark J.H., Fisher A.J. The Effect of Ex-Vivo Perfusion on the Inflammatory Profile of the Donor Lung Journal of Heart and Lung Transplantation 2010;29:2 Suppl: S165 Aynsley E., Clark S.C., Black F., Gardiner J., Mulvenna P. Adjuvant Chemotherapy for Non ~Small Cell Lung Cancer : The Need for a Further Trial in the Context of the New (Seventh) TNM Staging system for Lung and Pleura Lung Cancer (Conference Proceedings) 2010;67:S16 De Soyza A. Meachery G., Hester K.L., Nicholson A., Parry G., Tocewicz K., Pillay T., Clark S.C., Lordan J.L., Schueler S., Fisher A.J., Dark J.H., Gould F.K., Corris P.A. Lung transplantation for patients with Cystic Fibrosis and B. Cepacia complex infections: A single centre experience Journal of Heart and Lung Transplantation 2010 Dec; vol. 29(12) pp. 1395-404 Taggart D.P., Altman D.G., Gray A.M., Lees B., Nugara F., Yu L.M., Campbell H., Flather M. on behalf of the ART Investigators inc Clark S.C. Randomized trial to compare bilateral vs. single internal mammary coronary artery bypass grafting: 1-year results of the Arterial Revascularisation Trial (ART). European Heart Journal 2010 Oct; vol. 31(20) pp. 2470-81


Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of the Royal College of Surgeons of England 2010;92(7):623-7 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of the Royal College of Surgeons of England 2010;92(1):69-72 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Newsletter of the Association of Surgeons of Great Britain & Ireland 2010;32 (Dec);70-71 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Newsletter of the Association of Surgeons of Great Britain & Ireland 2010;31 (Sep);62-63 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Newsletter of the Association of Surgeons of Great Britain & Ireland 2010;30 (Jul);62-63 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Newsletter of the Association of Surgeons of Great Britain & Ireland 2010;29 (Mar);62-63 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee Selected Vascular Safety-Related Cases from CORESS. Newsletter of the Association of Surgeons of Great Britain & Ireland 2010 (February):7-8 Jones R., Nyawo B., Jamieson S., Clark S.C. Current smoking predicts increased operative mortality and morbidity after cardiac surgery in the elderly. Interactive Cardiovascular and Thoracic Surgery. 2011;12;3;449-454

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Banner N., Bonser R., Clark A., Clark S.C., Cowburn P., Gardner R., Kalra P., McDonagh T., Rogers C., Swan L., Parameshwar J., Thomas T., Williams S. UK Guidelines for Referral and Assessment of Adults for Heart Transplantation. Heart 2011;97;1520-1527 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of the Royal College of Surgeons of England 2011;93(4):318-20 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of the Royal College of Surgeons of England 2011;93(2):162-6 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Journal of the Association of Surgeons of Great Britain & Ireland 2011;35 (Dec);54-55 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Journal of the Association of Surgeons of Great Britain & Ireland 2011;34 (Aug);70-71 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Newsletter of the Association of Surgeons of Great Britain & Ireland 2011;33 (May);8-9 Clark S. C. Single lung transplantation with cardiopulmonary bypass. Multimedia Manual of Cardiothoracic Surgery 2011 vol. 2011(1116) pp. mmcts.2009.004267 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee Vascular CORESS Cases Newsletter of the Association of Surgeons of Great Britain & Ireland 2011(July):14


Kenny L., Clark S.C. Lung Resections in Octagenarians- 7 year Experience in a Single Centre WILL BE PUBLISHED IN SUPPLEMENT TO LUNG CANCER in January 2012 Clark S.C., Dunning J., Alfieri O.R., Elia S., Hamilton L.R., Kappetein A.P., Lockowandt U., Sarris G.E., Kolh P.H. EACTS Guidelines for the Use of Patient Safety Checklists. European Journal of Cardiothoracic Surgery 2012; 41 (5): 993-1004 Clark S. C., Zuckermann A. I2C2 – Bringing ISHLT to the World ISHLT Links 2012;4;1 Clark S. C., Wrightson N., Regnard C., Louw S. Guidelines for Withdrawal of Ventricular Assist Devices Palliative Medicine 2012;26(4); 492 Bonser R.S., Taylor R., Collett D., Thomas H.L., Dark J.H. on behalf of the Cardiothoracic Advisory Group to NHS Blood and Transplant inc Clark S.C. Effect of Donor Smoking on Survival after Lung Transplantation: A Cohort Study of a Prospective Registry The Lancet 2012;380 (9843), 747-55 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of the Royal College of Surgeons of England 2012;94(7):527-29 Birch J., Hester K., Parry G., Gould K., Dark J.H., Clark S.C., Meachery G., Lordan J., Fisher A.J., Corris P., De Soyza A. Outcomes of Lung Transplantation for Bronchiectasis European Respiratory Journal 2012;40;Suppl 56;2443 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of the Royal College of Surgeons of England 2012;94(4):283-5 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of the Royal College of Surgeons of England 2012;94(1):58-60 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Surgeons News (Royal College of Surgeons of Edinburgh) 2012;Sept:22-23

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Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Surgeons News (Royal College of Surgeons of Edinburgh) 2012;June:28-29 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Surgeons News (Royal College of Surgeons of Edinburgh) 2012;March:38-39 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee Vascular CORESS Cases Journal of the Association of Surgeons of Great Britain & Ireland 2012;37 (Sept);62-63 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee Vascular CORESS Cases Journal of the Association of Surgeons of Great Britain & Ireland 2012;36 (Mar);78-79 Burdett; C., Butt; T., Lordan J., Dark J.H., Clark S.C. Comparison of Single Lung Transplant with and without the Use of Cardiopulmonary Bypass Interactive Cardiovascular and Thoracic Surgery; 2012;15;432-436 Clark S. C., Wrightson N., Regnard C., Louw S. Guidelines for Withdrawal of Ventricular Assist Devices British Medical Journal (Supportive & Palliative Care) 2012;2:Suppl 1: A100 Bose A., Butt T. Muse H., Clark S.C. Importance of Early Recognition of Vascular Anastomotic Complications in Lung Transplantation Interactive Cardiovascular and Thoracic Surgery 2012;15;Suppl 2;S121 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee Journal of the Association of Surgeons of Great Britain & Ireland 2012;38 (Dec);62-63


Dark J.H., Karamanou D., Clark S.C., Mahesh P., Watson B., Corris P.A., Fisher A.J. Successful Transplantation of Unusable Donor Lungs using Ex Vivo Lung Perfusion – The Newcastle Experience The Journal of Heart and Lung Transplantation 2012; 31(4):S115. Siddique A., Bose A.,Ozalp F., Butt T. Muse H., Morley K. E., Dark J.H., Parry G., Clark S.C. Vascular Anastomotic Complications in Lung Transplantation : A Single Institutions Experience. Interactive Cardiovascular and Thoracic Surgery 2013; 1-7 Clark S. C., Hadjiliadis, Levine D., Verleden G. Pulmonary Transplantation Session Highlights ISHLT Links 2013;4;10 Clark S. C. I2C2 – Ambassadors Wanted ISHLT Links 2013;4;12 Bose A.K., Plummer C.J, Clark S.C. Tunnelling Defibrillator Leads from the Chest to the Abdomen for Chronic Pain Europace, 2013; 15(6); 844 Thomas H.I, Taylor R., Simon A.R., Clark S.C., Dunning J., Yonan N., Banner N., Dark J.H. Donation after Circulatory Death Lung Activity in the UK – 100 Transplants and Counting Journal of Heart and Lung Transplantation 2013;32:4S;15 Morley K.E., Muse H.K., Wallace K.N., Parry G., Clark S.C. Should Recipients choose their Donor? Experience with a New Consent Process in Lung Transplantation Journal of Heart and Lung Transplantation 2013;32:4S;43 Ranasinghe A., Clark S.C., Corris P.A., Fisher A.J., Gould K., Hamilton L., Lordan J., Meachery G., Morley K., Parry G., Perry A., Pillay T., Scheuler S., Tocewicz K., Dark J.H. Improving Outcomes in Lung Transplantation for Cystic Fibrosis – A Unified Approach Journal of Heart and Lung Transplantation 2013;32:4S;215 Kenny L.A., Slight R., Sarwar G., Clark S.C. Managing Bronchial Anastomotic Complications – The Influence of Aspergillosis Journal of Heart and Lung Transplantation 2013;32:4S;266

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Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of the Royal College of Surgeons of England 2013;95:305-6 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee Journal of the Association of Surgeons of Great Britain & Ireland 2013;39: 46-47 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee Journal of the Association of Surgeons of Great Britain & Ireland 2013;40;54-55 McKenna M., Wrightson N., Regnard C., Clark S. C. Withdrawal of Life Sustaining Medical Devices and Advance Care Planning British Medical Journal (Supportive & Palliative Care) 2013;3:5-7 Emin A, Rogers CA, Parameshwar J, Macgowan G, Taylor R, Yonan N, Simon A, Tsui S, Schueler S, Banner NR; Steering Group of the UK Cardiothoracic Transplant Audit (inc Clark S.C.) and the UK VAD Forum. Trends in long-term mechanical circulatory support for advanced heart failure in the United Kingdom European Journal of Heart Failure. 2013 Oct;15(10):1185-93. Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of the Royal College of Surgeons of England 2014;96:73-74 H.L. Thomas, R. Taylor, A.R. Simon, S.C. Clark, J. Dunning, N. Yonan, N.R. Banner, J.H. Dark Donation after Circulatory Death Lung Activity in the UK – 100 Transplants and Counting The Journal of Heart and Lung Transplantation 2014;32(4):S15. Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of The Royal College of Surgeons of England 2014;96;161-162 Andreasson A. S., Karamanou D., Perry J., Ӧzalp F., Butt T., Morley K., Walden H., Clark S. C., Prabhu M., Corris P.A., Gould K., Fisher A.J., Dark J.H. The Effect of Ex Vivo Lung Perfusion (EVLP) on the Microbial Load in Human Donor Lungs Accepted for publication in the Journal of Heart and Lung Transplantation 2014;


Robinson S., Wilson C., Clark S.C., Manas D. The Role of Cardiopulmonary Bypass in the Management of Retrohepatic Vena Cava Injury – A Case Report and Review of the Literature Accepted for publication in Injury 2014 Ong L.P.,Tristram Z., Prabhu M., Parry G., Clark S.C. Prolonged Intensive Care Unit Stay after Bilateral Lung Transplantation - Late Mortality & Functional Outcome? The Journal of Heart and Lung Transplantation 2014;33(4S);S294 Morley K., Clark S.C. Multi-Centre Experience of Donor Choice Consent Forms in the United Kingdom The Journal of Heart and Lung Transplantation 2014;33(4S);S300 Lannon J.D, Mandersloot G., Thomas H.L., Vercueil A., Venkateswaran R., Clark S.C., Sudarshan C., Al-Attar N., Zych B., Mascaro J., Murphy P., Tsui S. The United Kingdom Retrieval Team ‘Scout’ Pilot Programme The Journal of Heart and Lung Transplantation 2014;33(4S);S162 Lannon J.D., Ball A., Yonan N., Clark S.C., Mascaro J., Catarino P., Simon A., Dark J.H. The Effect of Cold and Warm Ischaemia Time on Survival after Lung Transplantation in a Large National Cohort The Journal of Heart and Lung Transplantation 2014;33(4S);S94 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of the Royal College of Surgeons of England 2014;96;323-325 Clark S.C., Dunning J. How to Place a Patient on Veno-Venous ECMO http://www.ctsnet.org/article/how-place-patient-veno-venous-ecmo CTSNet – The Cardiothoracic Surgery Network May 2014 Clark S.C. CORESS – The Confidential Reporting System for Surgery Bulletin of the Society for Cardiothoracic Surgery in Great Britain and Ireland – July 2014 Mownah O., Khurram M., Ray C., Coates R., Afridi F., Stamp S., Brassil J., Rees D., Majo J., Nair S., Clark S.C., MacGowan G., Dark J., Carter N., Talbot D. Resuscitation of Marginal Hearts Using Ex Vivo Perfusion American Journal of Transplantation 2014;14; S3;427

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Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of the Royal College of Surgeons of England 2014;96;490-493 Taggart D.P., Altman D.G., Gray A.M. Lees B., Nugara F., Yu L., Flather M. on behalf of the ART Investigators inc Clark S.C. Effects of On Pump and Off Pump Surgery in the Arterial Revascularisation Trial European Journal of Cardiothoracic Surgery 2014;1-7 Ong L. P., Tristan Z., Muse H.K., Wallace K., Whitehead S., Parry G. Clark S. C. Blood Transfusion after Lung Transplantation - Impact on Early Function and Survival Interactive Cardiovascular and Thoracic Surgery 2014;19: Suppl 1; 74 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee CORESS Feedback Annals of the Royal College of Surgeons of England 2014;96(4):635-637 Merlo C.A., Clark S.C., Arnaoutakis G.J., Yonan N., Thomas D., Simon A., Thompson R.,Thomas H., Orens J., Shah A.S. National Health Care Delivery Systems Influence Lung Transplant Outcomes for Cystic Fibrosis Accepted for publication in the American Journal of Transplantation 2015 McKenna M., Clark S.C. Palliative Care in Cardiopulmonary Transplantation Accepted for publication in the British Medical Journal (Supportive & Palliative Care) 2015 Ong L.P., Thompson E., Sachdeva A., Ramesh B.C., Muse H., Wallace K., Parry G., Clark S.C. Allogeneic Blood Transfusion in Bilateral Lung Transplantation – Impact on Early Function and Mortality Accepted for publication in the European Journal of Cardiothoracic Surgery 2015 Murphy G.J., Pike K., Rogers C.A., Wordsworth S., Stokes E.A., Angelini G.D., Reeves B. on behalf of the TITRE 2 Investigators including Clark S.C. Liberal or Restrictive Transfusion after Cardiac Surgery New England Journal of Medicine 2015;372;11;997-1008


Ong L.P., Thompson E., Sachdeva A., Ramesh B.C., Muse H., Wallace K., Parry G., Clark S.C. Blood Transfusion in Bilateral Lung Transplantation – Impact on Rejection, Functional and Late Survival Outcomes Accepted for publication in the The Annals of Thoracic Surgery Di Eusanio M., Phan K., Bouchard D., Carrel T. P., Dapunt O.E., Di Bartolomeo R., Eichstaedt H.C., Fischlein T., Folliguet T., Gersak B., Glauber M., Haverich A., Misfeld M., Oberwalder P.J, Santarpino G., Shrestha M.L., Solinas M., Vola M., Alamanni F., Albertini A., Bhatnagar G., Carrier M., Clark S.C., Collart F., Kappert U., Kocher A., Meuris B., Mignosa C., Ouda A., Pelletier A., Rahmanian P.B., Reineke D., Teoh K., Troise G., Villa E., Wahlers T., Yan T.D. Sutureless Aortic Valve Replacement International Registry (SU- AVR-IR): Design and Rationale from the International Valvular Surgery Study Group (IVSSG) Annals of Cardiothoracic Surgery 2015;4(2):131-139 McMinn J., Wrightson N., Parry G., Clark S.C., Scheuler S., MacGowan G. Who and When to Refer for Advanced Heart Failure? A Survey of Clinicians Referring to the Freeman Hospital Heart 2015;101:Suppl 4 A27-A28 Sithamparanathan S., Thirugnanasothy L., Fisher A.J., Lordan J., Meachery G., Dark J.H., Hasan A., Clark S.C., Gould K., MacGowan G.A., Parry G., Corris P.A. A Retrospective Observational Study Of 20 Year Lung Transplant Survivors - A Single Centre Experience. Thorax 2014; 12; 69;Suppl 2; A183-A184 Raju D., Roysam C., Singh R., Clark S.C. Plummer C. Unusual Cause of Hypoxemia after AICD Lead Extraction Journal of Cardiac Anaesthesia 2015;18;599-602 Clark S.C. with the Confidential Reporting System for Surgery Advisory Committee Confidential Reporting System for Surgery (CORESS) 2005-2015 – 10th Anniversary Supplement Clark S.C. Ranasinghe A. Cardiopulmonary Transplantation SAC and SCTS Cardiothoracic Surgery UK Workforce Report 2015 Clark S.C. Sutureless Rapid Deployment Valves and Stented Bioprosthesis in Aortic Valve Replacement: Recommendations of an International Expert Consensus Panel

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Accepted for publication in the European Journal of Cardiothoracic Surgery 2015 PUBLISHED LETTERS

Multiple Authors inc. Clark S.C. New Deal not Satisfactory for Cardiothoracic Surgery British Medical Journal 1995 Vol 311:953.


Clark S.C. Complications of Intra-Aortic Balloon Pumping. Annals of the Royal College of Surgeons of England 1996;78:155. Clark S.C., Barnard S.P. Emergency Room Thoracotomy: Is it ever justified ?. Annals of the Royal College of Surgeons of England 1996 ;78(6): 561. Clark S.C. Glyceryl Trinitrate prevents Neutrophil Activation but not Thromboxane Release following Ischaemia-Reperfusion Injury. British Journal of Surgery 1996;84:139. Sudarshan C.D., Clark S.C., Dark J.H. Single or Bilateral Lung Transplantation for Chronic Obstructive Pulmonary Disease. The Journal of Thoracic and Cardiovascular Surgery 1998;115:2,485.

Clark S.C., Zacharias J., Hamilton J.R.L.H., Hasan A. Coarctation with Valvular Lesions in Adults. Annals of Thoracic Surgery 1998;66:600-601. Clark S.C., Sudarshan C., Dark J.H. Summary Measures: A Superior Method of Data Analysis in Lung Preservation Studies. Journal of Heart & Lung Transplantation 1999;18.(2):172-173.

Vitale N., Clark S.C. Proposed Guidelines for Low Molecular Weight Heparin. Heart News 1999;1(5):191. Clark S.C., Sudarshan C.D., Dark J.H. Controlled Perfusion of the Transplanted Lung Annals of Thoracic Surgery 2001;71:1755-1756. Clark S.C. Antithrombotic Treatment in Patients with Unstable Coronary Artery Disease undergoing CABG. Annals of Thoracic Surgery 2001;71:1748-1749 Clark S.C. Are Surgeons aware of the dangers of diathermy? Annals of the Royal College of Surgeons of England 2002;84:369. Clark S. C., Hamilton J.R.L.H WHO Checklist needs to be customized by Specialty. British Medical Journal 2010: 340;589

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Clark S. C. Recipient Choice over Donor Organs – The Dangers of Rejecting Imperfect Lungs British Medical Journal – June 2010 Rapid Response Letter http://www.bmj.com/cgi/eletters/340/jun16_3/c3165 Botha P., Clark S. C., Dark J.H. Standardization of Transplant Procurement Procedures Journal of Thoracic and Cardiovascular Surgery 2010: 140(1);250 Clark S. C. Aviation Safety Methods in Surgery must be Relevant and Specific British Medical Journal – February 2011 Rapid Response Letter http://www.bmj.com/content/342/bmj.c7309/reply#bmj_el_250176?sid=6d459f8f-5f70-4a8c-ae97-a1a50a63c6ef Clark S. C. The Use of Cardiopulmonary Bypass in Lung Transplantation European Association for Cardiothoracic Surgery Daily News – October 2, 2011 McKenna M., Wrightson N., Regnard C., Clark S. C. Response to Withdrawal of Life Sustaining Medical Devices and Advance Care Planning British Medical Journal (Supportive & Palliative Care) 2013;3:10 Clark S.C. The Royal College of Surgeons in China Annals of the Royal College of Surgeons of England 2014;96;168 Clark S. C. Strategies for Ameliorating Lung Injury – A Missed Opportunity Interactive Cardiothoracic and Thoracic Surgery - Jan 2015 http://icvts.oxfordjournals.org/cgi/eletters/19/6/962#1841 Clark S.C. Where are the Surgeons? A Safety Opportunity Missed? Heart 2015;101;1434 Also on line at www.heart.bmj.com Clark S.C. Patient Safety in Thoracic Surgery and the European Society of Thoracic Surgeons Checklist


Journal of Thoracic Disease 2015;7(S2);S145-151 http://www.jthoracdis.com/article/view/4192/html

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BOOK CHAPTERS

Lung Transplantation in Introduction to Organ Transplantation Editor - N.S. Hakim. Imperial College Press, London. 1997 Cardiothoracic Transplantation A Companion to Specialist Surgical Practice: Transplantation

Editor – J. Forsythe Elsevier, London. 2005 3rd Edition

Lung Transplantation Core Topics in Thoracic Anaesthesia Cambridge University Press 2009 Cardiothoracic Transplantation

A Companion to Specialist Surgical Practice: Transplantation Editor – J. Forsythe Elsevier, London. 2009 4th Edition

Single Lung Transplantation with Cardiopulmonary Bypass Multimedia Manual of Cardiothoracic Surgery 2011 Oxford Assess and Progress – Oxford Handbook of Clinical Surgery (Reviewer of the Cardiothoracic Surgery Chapter) Oxford University Press 2011

MISCELLANEOUS PUBLICATIONS

Book Reviews Lung Transplantation – Eds Banner N., Polak J., Yacoub M. Clark S. C. Transplantation Society Newsletter July 2003 Kirklin/Barratt Boyes Cardiac Surgery 3rd Edition – Eds Kouchoukos N., Blackstone E., Doty D., Hanley F., Karp R. Clark S.C. European Journal of Vascular and Endovascular Surgery 2004;28(4):449


PRESENTATIONS & INVITED LECTURES Graff L.G., Clark S.C., Radford M.J. Critical Care by Emergency Physicians in American and English Hospitals. Presented at the First Congress of the Society for Academic Emergency Medicine Research at the Royal College of Surgeons of Edinburgh, October 1990. Clark S.C. Pulmonary Lymphangiomyomatosis. Presented at the National Heart and Lung Institute, London, October 1991. Naylor A.R., Clark S.C., London N., Sayers R., Bell P.R.F. Major Prosthetic Graft Infection - Success with In Situ Management Methods. Presented at the Midlands Surgical Society, Leicester, March 1993. Clark S.C Trauma Scoring Systems - An Overview and Application to Elective General Surgery Patients. Presented at The South West Regional Surgical Meeting, Bristol, June 1992. Clark S.C., Norton S., Ridley P., Jeyasingham K. Epiphrenic Diverticula - Case Report & Review of Management. Presented at The South West Regional Cardiothoracic Meeting, October 1993. Clark S.C., Norton S., Ridley P., Jeyasingham K. Oesophageal Diverticula - The Controversy in Surgical Management. Presented at The South West Regional Surgical Meeting, Bristol, October 1993. Also presented as an invited lecture to Professor J. Deslauriers (James IV Travelling Professor) upon his visit to Frenchay Hospital, Bristol in November 1993. Clark S.C., Dark J.H. The Timing of Leucocyte Sequestration after Single Lung Transplantation. Presented at the Cardiac Surgical Research Club at St Thomas’s Hospital, May 1995. Clark S.C., Levine A.J., Forty J., Hasan A., Hilton C.J., Dark J.H. Vascular Complications after Lung Transplantation. Presented at the Cardiac Surgical Research Club at St Thomas’s Hospital, May 1995.

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Clark S.C., Fagan D.G. Myocardial Hyperplasia in the Sudden Infant Death Syndrome. Presented at the Cardiac Surgical Research Club at Bristol Royal Infirmary, November 1995. Clark S.C., Levine A.J., Forty J., Hasan A., Hilton C.J., Dark J.H. Vascular Complications of Pulmonary Transplantation. Presented at the The European Society of Heart and Lung Transplantation (10th Meeting) in Wengen, Switzerland in January 1996. Clark S.C., Goodfellow J., Forty J. Consequences of Cardiac Surgery after Discharge from Hospital. Presented at The Society of Cardiothoracic Surgeons of Great Britain and Ireland in Llandudno, March 1996. Khanna R., Clark S.C., Dark J.H. Lung Transplantation with and without Cardiopulmonary Bypass. Presented at The Society of Cardiothoracic Surgeons of Great Britain and Ireland in Llandudno, March 1996. Clark S.C., Goodfellow J., Forty J. Consequences of Cardiac Surgery after Discharge from Hospital. Presented at the North of England Surgical Society in Newcastle upon Tyne, May 1996. Clark S.C., Khanna R., Dark J.H. Single Lung Transplantation with and without Cardiopulmonary Bypass. Presented at the North of England Surgical Society in Newcastle upon Tyne, May 1996. Clark S.C., Khanna R., Flecknell P.A., Dark J.H. Development of an Experimental Surgical Model to Evaluate Pulmonary Reperfusion Injury after Single Lung Transplantation. Invited presentation to Sir Rodney Sweetman, President of the Royal College of Surgeons of England on his visit to the Department of Surgery, University of Newcastle upon Tyne, July 1996. Clark S.C., Khanna R., Dark J.H. Single Lung Transplantation with and without Cardiopulmonary Bypass. Presented at the British Transplantation Society at The Royal College of Surgeons of England, London, October 1996. Clark S.C. Low Pressure Reperfusion of the Transplanted Lung in Pigs. Invited presentation to the Fourth Wythenshawe National Forum Meeting in Manchester, November 1996


Clark S.C., Sudarshan C.D., Flecknell P.A., Dark J.H. Controlled Reperfusion of Lung Grafts. Presented at the Geoffrey Giles Memorial Prize Competition in Leeds, November 1996. I was awarded the Geoffrey Giles Memorial Medal and Prize for this presentation. Clark S.C., Sudarshan C. D., Dark J.H., Kirby J.A. The Modulation of Neutrophil Adhesion to Fibronectin. Presented at the Cardiac Surgical Research Club in Coventry, November 1996. Clark S.C., Sudarshan C. D., Ali S., Dark J.H., Kirby J.A. An Assay of Neutrophil Adhesion to Fibronectin and its Attenuation by Pentoxifylline and Nitric Oxide. Presented at the Biochemical Society / British Society for Immunology Joint Congress in Harrogate, December 1996. Clark S.C., Sudarshan C.D., Flecknell P.A., Dark J.H. Pentoxifylline and Pressure Control in Lung Reperfusion Injury. Presented at the Society of Cardiothoracic Surgeons of Great Britain and Ireland meeting in Dublin, March 1997. Carey J., Clark S.C., Hasan A., Hamilton J.R.L.H. Orthotopic Cardiac Transplantation for the Failing Fontan Circulation. Presented at the Society of Cardiothoracic Surgeons of Great Britain and Ireland meeting in Dublin, March 1997. Clark S.C., Sudarshan C.D., Flecknell P.A., Dark J.H. Pentoxifylline and Pressure Control in Lung Reperfusion Injury. Presented in the Caves Award section of the International Society for Heart and Lung Transplantation in London, April 1997. Clark S.C., Sudarshan C. D., Ali S., Dark J.H., Kirby J.A. Neutrophil Transmigration - The Influence of Pentoxifylline and Nitric Oxide. Presented at the Biochemical Society in Bath, April 1997. Clark S.C., Sudarshan C.D., Flecknell P.A., Dark J.H. Pentoxifylline, Neutrophil Depletion and Pressure Control in Lung Reperfusion Injury Presented in the Medewar Medal section of The British Transplantation Society in Nottingham, April 1997. Clark S.C., Sudarshan C.D., Flecknell P.A., Dark J.H. Inositol Polyanions in Reperfusion Injury. Presented at the Tripartite Meeting of the Surgical Research Society, European Surgical Research Society and the Australasian Surgical Research Society in Nottingham, July 1997.

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Clark S.C., Sudarshan C.D., Flecknell P.A., Dark J.H. Attenuation of Reperfusion Injury of the Lung by the Nitric Oxide donor, SIN. Presented at the North of England Surgical Society, May 1996. Clark S.C., Goodfellow J., Forty J. An Audit of Morbidity Following Routine Cardiac Surgery Presented at Good Audit, Bad Audit Conference, The Royal College of Surgeons of England, June 1997. Clark S.C., Sudarshan C. D., Ali S., Dark J.H., Kirby J.A. Modulation of Neutrophil Adhesion and Transmigration by Pentoxifylline and Nitric Oxide. Presented at the 8th Congress of the European Society for Organ Transplantation in Budapest, September 1997. Clark S.C. Heart and Lung Transplantation. Invited lecture at the Northern Regional Transplant day at the Freeman Hospital, Newcastle upon Tyne, November 1997.

Clark S.C. The Newcastle Approach to Lung Preservation. Invited lecture at Papworth Hospital, Cambridge, December 1997. Clark S.C., Sudarshan C.D., Flecknell P.A., Dark J.H. A Comparison of Pulmonary Reperfusion Injury after Leucocyte Depletion, Pentoxifylline and Nitric Oxide Donor. Presented in the Caves Award section of the International Society for Heart and Lung Transplantation in Chicago, April 1998. Clark S.C., Sudarshan C. D., Ali S., Dark J.H., Kirby J.A. Interleukin 8 Expression after Pharmacological Attenuation of Pulmonary Reperfusion Injury. Presented at the International Society for Heart and Lung Transplantation in Chicago, April 1998. Clark S.C., Sudarshan C.D., Flecknell P.A., Dark J.H. Pharmacological and Physiological Modulation of Reperfusion Injury after Lung Transplantation. Presented at The Society of Cardiothoracic Surgeons of Great Britain and Ireland in Edinburgh, March 1998. Judged paper of best scientific content (David Cooper Prize) at the 1998 meeting.


Clark S.C., Vitale N., Zacharias J., Forty J. The Influence of Low Molecular Weight Heparin (Fragmin) on Coronary Artery Surgery for Unstable Angina. Presented at The Society of Cardiothoracic Surgeons of Great Britain and Ireland in Edinburgh, March 1998. Zacharias J., Owens W.A., Clark S.C., Hamilton J.R.L.H. Rationing for CABG : Use of New Zealand Scores. Presented at The Society of Cardiothoracic Surgeons of Great Britain and Ireland in Edinburgh, March 1998. Clark S.C., Sudarshan C. D., Dark J.H., Kirby J.A. Interleukin 8 and its Modulation in Reperfusion Injury. Presented at the 1st Annual Congress of the British Transplantation Society in Dublin, April 1998. Vitale N., Clark S.C., Zacharias J., Forty J. Influenza dell 'Eparina a Basso Peso Moleculare nel Sanguina-Mento Postoperatorio in Pazienti con Angina Instabile. Presented at the Congresso Nazionale della Societa Italiana di Chirurgia Cardiacae Vascolare in Pavia, Italy, May 1998. Clark S.C., Chapman K., Orr K., Forty J., Wallis J. The Effects of Leucocyte Deplete Blood Transfusion after Cardiac Surgery Presented at the European Association for Cardiothoracic Surgery in Brussels, September 1998. Clark S.C. The Future of Lung Transplantation. Invited lecture at The Royal College of Nursing Transplant Forum meeting at the Freeman Hospital, Newcastle upon Tyne, September 1998. Hasan A., Redhead T., Clark S.C., Ledingham S.J.M. Superior Harvesting of the Radial Artery using the Harmonic Scalpel Presented at the International Congress of Cardiovascular and Thoracic Surgery in Karachi, Pakistan, December 1998 Sudarshan C., Orr H., Clark S.C., Roughan J., Flecknell P.A., Dark J.H. Donor Pre-Treatment with Inhaled Nitric Oxide Attenuates Acute Lung Injury following Single Lung Transplantation. Presented at the International Society for Heart and Lung Transplantation in San Francisco, California, April 1999. Redhead T., Clark S.C., Hasan A., Ledingham S.J.M. Superior Harvesting of the Radial Artery using the Harmonic Scalpel. Presented at The Society of Cardiothoracic Surgeons of Great Britain and Ireland in Nottingham, March 1999.

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Clark S.C., Chapman K., Orr K., Forty J., Wallis J. Effect of Leucocyte Deplete Blood Transfusion on Infections after Cardiac Surgery. Presented at The Society of Cardiothoracic Surgeons of Great Britain and Ireland in Nottingham, March 1999.

Sudarshan C.D., Clark S.C., Roughan J., Flecknell P.A., Haynes S., Dark J.H. Brief Exposure of the Donor to Inhaled Nitric oxide Improves Early Pulmonary Graft Function. Presented in the Patey Prize section of The Surgical Research Society meeting in Brighton, May 1999. Sudarshan C.D., Antunes L.M., Clark S.C., Roughan J., Flecknell P.A., Dark J.H. Donor Pre-treatment with Inhaled Nitric Oxide Improves Early Outcome in Single Lung Transplantation. Presented at the Congress of the International Society for Organ Sharing in Maastricht, April 1999. Sudarshan C.D., Clark S.C., Roughan J., Flecknell P.A., Haynes S., Dark J.H. Donor Pre-treatment with Inhaled Nitric Oxide Improves Early Outcome in Single Lung Transplantation. Presented at the European Society of Organ Transplantation in Oslo, June 1999. Clark S.C. Inositol Polyanions Modulate Injury after Lung Transplantation. Presented at the European Society of Organ Transplantation in Oslo, June 1999. Wigfield C.W., Clark S.C. Single Lung Transplantation With and Without Cardiopulmonary Bypass. Presented at the European Society of Organ Transplantation in Oslo, June 1999 Clark S.C. Advances in Lung Transplantation. Invited lecture to The Intensive Care Society Annual Meeting in Durham, August 1999 Clark S.C. Advancing the Frontiers of Surgical Research. Invited lecture at The Royal College of Surgeons of England in London, November 1999.


Sudarshan C.D., Clark S.C., Flecknell P.A., Haynes S., Dark J.H. Inhaled Nitric Oxide over the First Ten Minutes of Lung Reperfusion Compared with Later Exposure Attenuates Acute Lung Injury in a Transplant Model. Presented at the International Society for Heart and Lung Transplantation in Osaka, Japan, April 2000. Rao J., Clark S.C., Sudarshan C.D., Flecknell P.A., Dark J.H. Improvements in Lung Compliance after Pulmonary Transplantation – Correlation with IL-8 Expression. Presented at the European Association of Cardiothoracic Surgery meeting in Frankfurt, Germany, October 2000 Clark S.C. Reperfusion Injury. Invited lecture to The Association of Cardiothoracic Anaesthetists – Symposium on Cardiopulmonary Transplantation at the Freeman Hospital, Newcastle upon Tyne, February 2001. Niranjan G., Perreas K., Redhead T., Clark S.C. Initial Experience with the Symmetry Aortic Connector for Proximal Anastomosis in CABG. Presented at the European Association of Cardiothoracic Surgery meeting in Lisbon, September 2001 Clark S.C. Early Experience with the Symmetry Bypass System Aortic Connector Presented at the Learning from Experience Symposium at the European Association of Cardiothoracic Surgery meeting in Lisbon, September 2001. Clark S.C. Coronary Artery Bypass Surgery in the Modern Era. Invited lecture to the Northern Region Cardiology Meeting in Newcastle upon Tyne, September 2001. Clark S.C. Left Ventricular Assist Devices Invited lecture at the Regional Transplant Study Day, Freeman Hospital, Newcastle upon Tyne, December 2001. Clark S.C. Frontiers for the Viable Myocardium and Surgical Options in Heart Failure. Invited lecture to the Northern Cardiology Group, held at The Stadium of Light, Sunderland, April 2002.

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Clark S.C. Automatic Anastomosis Devices in On Pump Surgery. Invited lecture at the Evolution of Facilitated Anastomosis meeting in Genval, Belgium, June 2002. Niranjan G., Perreas K., Redhead T., Pillay T., Clark S.C. Reduction of Bypass Time with the Symmetry Connector. Presented at the Annual Techno-College of the European Association of Cardiothoracic Surgery meeting in Monte Carlo, September 2002. Clark S.C. Indications for Facilitated Anastomosis in On Pump Surgery. Invited lecture at the Evolution of Facilitated Anastomosis meeting in Monte Carlo, Monaco, September 2002. Clark S.C. The Future of Heart Transplantation. Invited lecture to The Association of Cardiothoracic Surgical Assistants in Newcastle upon Tyne, January 2003. Clark S.C. Pharmacological Agents to Prevent Postoperative Bleeding. Invited lecture at the “Blood At The Sharp End” conference at The Centre for Life, Newcastle upon Tyne, January 2003. Clark S.C. Heart and Lung Transplantation. Invited lecture to Northumbria University School of Health Community & Education Studies, March 2003. Clark A. K., Clark S. C., Barnard S., Peel E.T. Is Video Assisted Thoracoscopy (VAT) a Diagnostic or Palliative Procedure in Patients with Malignant Pleural Effusion? Presented at the European Association of Palliative Care Congress in The Hague in April 2003. Gupta A.J., Ahmad I., Clark S.C., Gould K. A rare case of Candida Famata. Presented at the Royal Society of Medicine in May 2003. This presentation won the prize for best presentation at the meeting. Clark S.C. New Strategies in Immunosuppression after Thoracic Organ Transplantation Invited lecture at the European Society for Organ Transplantation in Venice, September 2003.


Clark S.C. Early Complications after Lung Transplantation Invited lecture to the British Thoracic Society at their Lung Transplantation Course held at the Freeman Hospital, Newcastle upon Tyne. Reddy S., Pillai J., Mitchell L., Naik S., Dark J.H., Hasan A., Ledingham S., Clark S.C. The First ever Report on No React Bovine Internal Mammary Artery Performance and Patency. Presented at the Cardiothoracic Technologies and Techniques Conference in Miami, USA in March 2004 Clark S.C. Leukocyte Filtration in Pulmonary Transplantation Invited Lecture at the 4th Therapeutic Filtration and Extracorporeal Circulation meeting at the Hammersmith Hospital, London in July 2004 Clark S.C. Minimally Invasive Cardiac Surgery. Invited lecture for the The Royal College of Surgeons of England Northern Regional Teaching Day at the Royal Victoria Infirmary, Newcastle upon Tyne in November 2004. Clark S.C. Pharmacological Reduction of Blood Loss Invited Lecture to the North of England Surgical Society in Newcastle upon Tyne in March 2005. Clark S.C. Early Complications after Lung Transplantation Invited lecture to the British Thoracic Society Lung Transplantation Course in Newcastle upon Tyne in April 2005.

Clark S.C. Pharmacological Agents to Prevent Postoperative Bleeding. Invited lecture at the Blood Bank Managers conference at Regional Blood Transfusion Centre, Newcastle upon Tyne, January 2003. Butt T., Aitchison D.A., Wardle J., Clark S.C., Dark J.H. Lung Transplantation from Non Heart Beating Donors without Pretreatment Presented at the Society of Cardiothoracic Surgeons of Great Britain and Ireland Meeting in Manchester in March 2007 Botha P., Jeyakanthan M., Rao J., Fisher A., Prabhu M, Dark J.H, Clark S.C. Prophylactic Inhaled Nitric Oxide for the Amelioration of Reperfusion Injury in Lung Transplantation Presented at the Society of Cardiothoracic Surgeons of Great Britain and Ireland Meeting in Manchester in March 2007

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Adwan H.M., Nyawo B., Jamieson S., Clark S.C. Comparison of Hospital mortality and morbidity of Cardiac Surgery in Octo/Nonagenarians in Upper and Lower Age Groups Presented at the 56th European Society for Cardiovascular Surgery in Venice in May 2007. Butt T.A., Aitchison J.D., Corris P.A., Wardle J., Clark S. C. , Dark J.H. Lung Transplantation from Deceased Donors without Pre Treatment Presented at The International Society of Heart and Lung Transplantation meeting held in San Francisco in April 2007 Meachery G.J., Archer L., de Soyza A., Parry G., Clark S. C., Tocewicz K., Fsher A., Lordan J., Scheuler S., Gould F.K., Dark J.H., Corris P.A. Survival Outcomes following Lung Transplantation for Cystic Fibrosis patients infected with Burkholderia Cenocepacia - A UK Experience Presented at the International Society of Heart and Lung Transplantation meeting held in San Francisco in April 2007 Botha P., Jeyakanthan M., Rao J., Fisher A., Prabhu M, Dark J.H, Clark S.C. Prophylactic Inhaled Nitric Oxide for the Prevention of Primary Lung Allograft Dysfunction Presented in the George Feggetter Medal section of the Annual Meeting of the North of England Surgical Society in Newcastle upon Tyne in May 2007. Wigfield C.H., Clark S.C. A Review of cardiopulmonary bypass support for non cardiac surgical procedures Presented at the Society of Clinical Perfusion Scientists Meeting in London in November 2007 Clark S.C. Ventricular Assist Devices. Invited Lecture. Bypass, Balloon Pumps and Circulatory Support Course at The Royal College of Surgeons of England in June 2007 Adwan H.M., Jamieson S.C., Nyawo B., Clark S.C. Comparison of Hospital Mortality and morbidity of cardiac surgery in Octo/Nonagenarians in lower and upper age groups Presented at the 56th International Congress of the European Society for Cardiovascular Surgery in May 2007 in Venice. Lewis A.J.M., Aitchison D.A., Clark S.C., Love R.B., Wigfield C.H. Evaluation of Cardiothoracic Out of Programme Experience Presented at the Association of Surgeons in Training Conference in Birmingham in March 2008.


Clark S.C. Early Complications after Lung Transplantation Invited lecture to the British Thoracic Society Lung Transplantation Course in Newcastle upon Tyne in March 2008. Butt T., Corris P., Clark S.C., Dark J.H. Lung Transplantation from Non Heart Beating Donors without Pre Treatment Presented at the British Transplantation Society in April 2008. Clark S.C. Ventricular Assist Devices. Invited Lecture. Bypass, Balloon Pumps and Circulatory Support Course at The Royal College of Surgeons of England in June 2008 Clark S.C. Blood Conservation in Cardiac Surgery Invited lecture at the Annual Education Symposium of the Yorkshire & Humberside and North East Regional Transfusion Committees – National Blood Transfusion Service in September 2008. Clark S. C. et al Burdett C. Invasive Biopsy is Effective and Useful after Lung Transplant Presented at the International Society for Heart and Lung Transplantation in Paris in April 2009 Clark S.C. Ventricular Assist Devices. Invited Lecture. Bypass, Balloon Pumps and Circulatory Support Course at The Royal College of Surgeons of England in June 2009 Karamanou D., Bean S., Prabhu M., Walden H., Clark S., Corris P.A., Dark J.H The Effect of Ex Vivo Lung Perfusion on Proinflammatory and Anti-Inflammatory Cytokines in the Human Lung. Presented at the British Thoracic Society in 2009 Aynsley E., Clark S.C., Gardiner J., Mulvenna P. Adjuvant Chemotherapy for Non Small Cell Lung Cancer – The need for a Further Trial in the Context of the New (Seventh) TNM Staging System. Presented at the 10th Annual British Thoracic Oncology Group meeting in Dublin in January 2010. Karamanou D., Bean S., Prabhu M., Walden H., Clark S.C., Corris P.A., Dark J.H The Effect of Ex Vivo Lung Perfusion on Proinflammatory and Anti-Inflammatory Cytokines in the Human Lung. Presented at the Society for Cardiothoracic Surgery of Great Britain and Ireland meeting in Liverpool in March 2010

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Clark S.C. Early Complications after Lung Transplantation. Invited lecture to the British Thoracic Society at their Lung Transplantation Course held in Newcastle upon Tyne in March 2010. Shanmuganathan S., Butt T., Clark S. C. Outcome of Lung Graft Volume Reduction for Oversized Donors during Pulmonary Transplantation Presented at the International Society of Heart and Lung Transplantation meeting held in Chicago in April 2010 Karamanou D., Walden H., Bean S., Prabhu M., Clark S. C. Simpson A., Corris P., Dark J.H., Fisher A.J. The Effect of Ex-Vivo Perfusion on the Inflammatory Profile of the Donor Lung Presented at the International Society of Heart and Lung Transplantation meeting held in Chicago in April 2010 Jones R.T., Nyawo B., Jamieson S. Clark S. C. Current Smoking predicts Increased Operative Mortality and Morbidity after Cardiac Surgery in the Elderly Presented at the 59th International Congress of the European Society for Cardiovascular Surgery in Izmir, Turkey in April 2010 Clark S.C. Ventricular Assist Devices. Invited Lecture. Bypass, Balloon Pumps and Circulatory Support Course at The Royal College of Surgeons of England in June 2010 Barnes S., Clark S. C. The Cardiac Surgery Patient Safety Checklist Accepted for presentation at the 12th Annual Nursing and Midwifery Conference in Newcastle in July 2010. Taggart D.P., Altman D.G., Gray A.M., Lees B., Nugara F., Yu L.M., Campbell H., Flather M. on behalf of the ART Investigators – (Clark S.C. Principle Investigator in Newcastle) Randomised Trial to Compare Bilateral Versus Single Internal Mammary Coronary Artery Bypass Grafting: One Year Results of the Arterial Revascularisation Trial (ART) Presented at the European Society of Cardiology meeting in Stockholm in August 2010. Clark S.C. Cardiac Surgical Safety Checklists – Are they worth the Effort? Invited Lecture Presented at the European Association for Cardiothoracic Surgery 24th Annual Meeting – Geneva, Switzerland in September 2010.


Clark S. C. Minimally Invasive Approaches to Valvular Heart Disease in Older Patients Invited Lecture Presented at the British Geriatrics Society Annual Meeting in Brighton in November 2010 Barnes S., Clark S. C. The WHO Patient Safety Checklist in Cardiac Surgery Accepted for presentation at Risk and Patient Safety 2010 in London in November 2010. Oezalp F., Butt T., Meachery J., Dark J.H., Clark S.C. Managing the Black Bronchus Presented at the European Society for Heart and Lung Transplantation in Switzerland in January 2011. Burdett C., Butt T., Clark S. C. Single Lung Transplantation with and without Cardiopulmonary Bypass. Presented at the British Thoracic Society Annual Congress in March 2011. Laidler S., Macfarlane R., Clarke L., Naden S., Newberry G., Thompson F., Stamenkovic S.A., Clark S.C. Reflection on the Implementation of a Nurse Practitioner Training Programme in a Large Cardiothoracic Surgical Unit. Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in London in March 2011. Winner of the 2011 SCTS Prize for Best Presentation at the Cardiothoracic Forum Hillier C.E., Clark S.C. CICU Readmission Rates in Cardiac Surgery Patients: A Retrospective Audit Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in London in March 2011. Shanmuganathan S., Butt T., Dark J.H., Clark S.C. Outcome of Lung Volume Reduction for Oversized Donors during Pulmonary Transplantation. Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in London in March 2011. Clark S.C. Cardiac Surgical Checklists – are they worth the effort? Invited Lecture Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in London in March 2011.

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Clark S.C. Cardiopulmonary Bypass Strategies for Double Lung Transplantation Invited Lecture Presented at the International Society of Heart and Lung Transplantation Annual Meeting in San Diego in April 2011. Clark S.C. Sharing Hearts Around the World – What works and what fails in National Systems – United Kingdom Invited Lecture Presented at the International Society of Heart and Lung Transplantation Annual Meeting in San Diego in April 2011. Clark S.C. Thoracic Surgery in Palliative Care Invited Lecture Presented at the Regional Educational Meeting – Cumberland Royal Infirmary, Carlisle in May 2011. Clark S.C. The Shortage of Lung Donors – How to Increase the Pool Invited Lecture Presented at the Society for Safety and Quality in Organ Transplantation Annual Meeting in Florence in May 2011. Barnes S., Clark S. C. The WHO Patient Safety Checklist in Cardiac Surgery – One Year On Accepted for presentation at Risk and Patient Safety 2011 in London in November 2011. Clark S.C. The Use of Cardiopulmonary Bypass in Lung Transplantation Invited Lecture Presented at the 25th Annual Meeting of the European Association of Cardiothoracic Surgery in October 2011 in Lisbon Burdett C., Butt T.A., Dark J.H., Clark S.C. Comparison of Single Lung Transplantation with and without Cardiopulmonary Bypass Presented at the 25th Annual Meeting of the European Association of Cardiothoracic Surgery in October 2011 in Lisbon Kenny L., Clark S.C. Lung Resections in Octagenarians- 7 year Experience in a Single Centre Presented at the British Thoracic Oncology Group Annual Meeting in January 2012


Bose A., A. Siddique, Oezalp F., Butt T., Dark J.H., Clark S.C. Managing Vascular Anastomotic Complications after Pulmonary Transplantation Presented at the European Association of Heart and Lung Transplantation in Switzerland in January 2012. Clark S.C. Experience with Asanguineous Perfusion and the Vivoline System Invited lecture Presented at the 13th International Symposium on Lung Transplantation at the University of Leuven, Belgium in March 2012. Clark S. C., Wrightson N., Regnard C., Louw S. Guidelines for the Withdrawal of Ventricular Assist Devices Presented at the 9th United Kingdom Palliative Care Congress in Newcastle in March 2012. Clark S.C. Invited Lecture Ex Vivo Lung Perfusion and the Vivoline System International Society for Heart and Lung Transplantation Annual Meeting in Prague in April 2012. Bose A., Clark S. C., Wrightson N., Regnard C., Louw S. Guidelines for the Withdrawal of Ventricular Assist Device Support Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in April 2012. Bose A., Muse H., Morley K., Dark J.H., Clark S. C. Outcome of Lung Transplantation in Those with a Prolonged Intensive Care Stay Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in April 2012. Bose A., Muse H., Morley K., Kenny L., Dark J.H., Clark S. C. Importance of Early Recognition of Vascular Anastomotic Complications in Lung Transplantation Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in April 2012. Wilson M., Niranjan G., Clark S. C. Implications of Delayed Discharge in a Large Adult Cardiothoracic Centre Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in April 2012.

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Laidler S., Niranjan G., Clark S. C. Worthwhile or Worthless? Routine Post operative Echocardiography after Valve Surgery Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in April 2012. Kenny L., Stamenkovic S., Barnard S., Forty J., Prabhu M., Somisetty S., Clark S. C. The Impact of Admission to the Intensive Care Unit after Thoracic Surgery Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in April 2012. Kenny L., Nyawo B., Stamenkovic S., Barnard S., Clark S. C., G. Sarwar, Forty J., Pulmonary Lobectomy in Octagenarians – A 9 Year Experience in a Single Centre Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in April 2012. Dark J.H., Karamanou D., Clark S.C., Prabhu M, Watson B., Corris P.A., Fisher A. Successful Transplantation of Unusable Donor Lungs using Ex Vivo Lung Perfusion – The Newcastle Experience. Presented at the International Society for Heart and Lung Transplantation Annual Meeting in Prague in April 2012. Wrightson N., Louw S., Regnard C., Clark S. C. Guidelines for Withdrawal of Ventricular Assist Device Therapy at End of Life Presented at the International Society for Heart and Lung Transplantation Annual Meeting in Prague in April 2012. Birch J., Hester K., Parry G., Gould K., Dark J.H., Clark S.C., Meachery G., Lordan J., Fisher A.J., Corris P., De Soyza A. Outcomes of Lung Transplantation for Bronchiectasis Presented at the European Respiratory Society Annual Congress in 2012 Clark S. C. TAVI – The Transapical and Transaortic Approach Invited lecture Presented at the Modern Management of Aortic Valve Disease Course at Freeman Hospital, Newcastle upon Tyne in May 2012. Madhavan A., Niranjan G., Clark S.C. Mini-Sternotomy for Necrotizing Mediastinitis Presented at the Annual Meeting of the International Society for Minimally Invasive Cardiothoracic Surgery in Los Angeles in June 2012.


Clark S.C. Early Complications after Lung Transplantation Invited lecture Presented at the British Thoracic Society Lung Transplantation Course held in Newcastle upon Tyne in October 2012. Clark S. C. Factors Contributing to Poor Early Outcomes after Cardiac Transplantation Invited Lecture Presented at the 25th Anniversary of Transplantation meeting in Manchester in October 2012. Bose A., Siddique A., Özalp F., Butt T., Dark J. H., Clark S. C. Importance of Early Recognition of Vascular Anastomotic Complications in Lung Transplantation Presented at the 26th Annual Meeting of the European Association of Cardiothoracic Surgery in October 2012 in Barcelona Thomas H.I, Taylor R., Simon A.R., Clark S.C., Dunning J., Yonan N., Banner N., Dark J.H. Donation after Circulatory Death Lung Activity in the UK – 100 Transplants and Counting Presented at the International Society of Heart and Lung Transplantation Annual Meeting in Montreal in April 2013. Morley K.E., Muse H.K., Wallace K.N., Parry G., Clark S.C. Should Recipients choose their Donor? Experience with a New Consent Process in Lung Transplantation Presented at the International Society of Heart and Lung Transplantation Annual Meeting in Montreal in April 2013. Ranasinghe A., Clark S.C., Corris P.A., Fisher A.J., Gould K., Hamilton L., Lordan J., Meachery G., Morley K., Parry G., Perry A., Pillay T., Scheuler S., Tocewicz K., Dark J.H. Improving Outcomes in Lung Transplantation for Cystic Fibrosis – A Unified Approach Presented at the International Society of Heart and Lung Transplantation Annual Meeting in Montreal in April 2013. Kenny L.A., Slight R., Sarwar G., Clark S.C. Managing Bronchial Anastomotic Complications – The Influence of Aspergillosis Presented at the International Society of Heart and Lung Transplantation Annual Meeting in Montreal in April 2013.

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Clark S.C. Invited Lecture Expanding and Maximising the Donor Pool : Improved Donor Management - UK Experience Presented at the International Society for Heart and Lung Transplantation Annual Meeting in Montreal in April 2013. Matthews I.G., McDiarmid A., Parry G., Clark S.C., Dark J.H., McComb J.M., Lord S. Radiofrequency Ablation of Late Atrial Flutter in Adult Orthotopic Cardiac Transplantation : A Single Centre Experience Presented at the Heart Rhythm Society Annual Meeting in Denver, Colorado, USA in May 2013. Clark S.C. Invited Lecture The UK Scout Pilot Project – Increasing Heart Donation Presented at the Northern Region Organ Donation Collaborative Meeting in Hexham, UK in May 2013. Morley K.E., Muse H.K., Wallace K.N., Parry G., Clark S.C. Should Recipients choose their Donor? Experience with a New Consent Process in Lung Transplantation Presented at the National Donation and Transplantation Congress in Warwick in September 2013. Jackson M., Tristram Z., Edwards R., Clark S.C., Oezalp F. Transpical TAVI for Torrential Aortic Regurgitation in a Patient with Acute on Chronic Dissection Presented at the PCR London Valves meeting in London in September 2013. Raju D., Roysam C., Clark S.C., Chaudhari M., Plummer C, Singh R.K. An Unusual Cause of Hypoxemia after Implantable Cardioverter Defibrillator Lead Extraction Presented at the Annual Meeting of the Association of Cardiothoracic Anaesthetists in Nottingham in November 2013 Tristram Z., Jackson M., Edwards R., Clark S.C. Transpical TAVI for Torrential Aortic Regurgitation in a Patient with Acute on Chronic Dissection Presented at the Royal Society of Medicine (Cardiothoracic Section) meeting in London in November 2013. Clark S.C. Invited Lecture Ex Vivo Lung Perfusion Presented at the NHSBT Organ Retrieval Masterclass at Oxford University, UK in December 2013.


Clark S.C. Invited Lecture Donor Scouting for Cardiac Transplantation Presented at the British Association of Critical Care Nurses in Gateshead, UK in January 2014. Ping L.P., Tristan Z., Muse H., Wallace K., Whitehead S., Parry G., Clark S.C. Blood Transfusion After Lung Transplantation - Impact on Early Function and Survival Presented at the British Transplantation Society Congress in Glasgow in February 2014. Slight B. Bernstein M., Stemenkovic S., Clark S.C., Forty J. First UK Experience of Robotically Assisted Thoracic Surgery Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Edinburgh in March 2014. Tristram Z., Jackson M., Edwards R., Clark S.C. Valve in Valve TAVI for Mitral Regurgitation Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Edinburgh in March 2014. Morley K. Clark S.C. A National Study of Donor Decisions in Cardiopulmonary Transplantation Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Edinburgh in March 2014. This work won the SCTS prize for the best Cardiothoracic Forum Presentation at the meeting. Clark S.C. Early Complications after Lung Transplantation Invited lecture Presented at the British Thoracic Society at their Lung Transplantation Course held at the Freeman Hospital, Newcastle upon Tyne in March 2014. Clark S.C Invited Lecture Cardiopulmonary Bypass in the Management of Abdominal Inferior Vena Caval Injury Presented at the 2nd Northern Regional Trauma Conference in Newcastle in March 2014 Ong L.P.,Tristram Z., Prabhu M., Parry G., Clark S.C. Prolonged Intensive Care Unit Stay after Bilateral Lung Transplantation - Late Mortality & Functional Outcome? Presented at the International Society for Heart and Lung Transplantation Annual Meeting in San Diego in April 2014.

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Morley K., Clark S.C. Multi-Centre Experience of Donor Choice Consent Forms in the United Kingdom Presented at the International Society for Heart and Lung Transplantation Annual Meeting in San Diego in April 2014. Lannon J.D, Mandersloot G., Thomas H.L., Vercueil A., Venkateswaran R., Clark S.C., Sudarshan C., Al-Attar N., Zych B., Mascaro J., Murphy P., Tsui S. The United Kingdom Retrieval Team ‘Scout’ Pilot Programme Presented at the International Society for Heart and Lung Transplantation Annual Meeting in San Diego in April 2014. Lannon J.D., Ball A., Yonan N., Clark S.C., Mascaro J., Catarino P., Simon A., Dark J.H. The Effect of Cold and Warm Ischaemia Time on Survival after Lung Transplantation in a Large National Cohort Presented at the International Society for Heart and Lung Transplantation Annual Meeting in San Diego in April 2014. Mownah OA, Khurram MA, Ray C, Coates R, Afridi F, Stamp S, Carter NM, Brassil J, Rees D, Majo J, Nair S, Clark S.C., MacGowan GA, Dark J, Talbot D. An Ex Vivo Perfusion System to Achieve Recovery of Hearts Sourced from Marginal Donors. Presented at the International Meeting On Ischemia Reperfusion Injuries in Transplantation (IMIRT) in Poitiers, France in April 2014. Tristram Z., Robinson S., Wilson C., Manas D., Clark S.C. The role of cardiopulmonary bypass in the management of retrohepatic vena cava injury. Presented at the Royal Society of Medicine Cardiothoracic Trauma Conference in London in June 2014. Clark S.C. Invited Lecture Perceval Sutureless Aortic Valve : How, when, what patient and why? Presented at the 2nd Perceval Valve UK and Ireland Focus Group Meeting in London in June 2014 Clark S. C. Invited Lecture Surviving Penetrating Injuries in 2014 Presented at the Cutting Edge of Medicine event for the Newcastle upon Tyne Hospitals NHS Foundation Trust Governors and Members in July 2014.


Mownah O., Khurram M., Ray C., Coates R., Afridi F., Stamp S., Brassil J., Rees D., Majo J., Nair S., Clark S.C., MacGowan G., Dark J., Carter N., Talbot D. Resuscitation of Marginal Hearts Using Ex Vivo Perfusion Presented at the World Transplant Congress in San Francisco in July 2014. Clark S.C. Invited Lecture Robot Assisted Thoracic Surgery Presented at the North of England Thoracic Society meeting in Durham in October 2014. Ong L. P., Tristan Z., Muse H.K., Wallace K., Whitehead S., Parry G. Clark S. C. Blood Transfusion after Lung Transplantation : Impact on Early Function and Survival Presented at the 28th Annual Meeting of the European Association of Cardiothoracic Surgery in October 2014 in Milan. Clark S.C. Invited lecture Aortic Root Aneurysms Presented at the 16th Annual Scientific Meeting Postgraduate Review Course of the Malaysian Association for Thoracic and Cardiovascular Surgery in Putrajaya, Kuala Lumpur, Malaysia in October 2014. Clark S.C. Invited lecture Alternatives to Heart Transplantation Presented at the 16th Annual Scientific Meeting of the Malaysian Association for Thoracic and Cardiovascular Surgery in Putrajaya, Kuala Lumpur, Malaysia in October 2014. Clark S.C. Invited lecture The State of Heart Transplantation Presented at the Royal College of Physicians of Edinburgh Cardiology Symposium in November 2014. Ong L. P., Tristan Z., Muse H.K., Wallace K., Whitehead S., Parry G. Clark S. C. Blood Transfusion after Lung Transplantation Presented at the 2nd National CQUIN Meeting for Cardiopulmonary Transplantation in Manchester in November 2014. Ong L. P., Thompson E., Tristan Z., Muse H.K., Wallace K., Whitehead S., Parry G. Clark S. C. Allogeneic Blood Transfusion after Lung Transplantation : Impact on Early Rejection, Function and Survival Presented at the 51st Annual Meeting of the Society of Thoracic Surgeons in January 2015 in San Diego.

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Slight B., Bernstein M., Clark S.C. , Stamenkovic S.A., Forty J. First UK Experience of Robotically Assisted Pulmonary Lobectomy using the Da Vinci Si Presented at the British Thoracic Oncology Group Annual Meeting in Dublin in January 2015. Clark S.C. Invited lecture Challenges and Opportunities – Heart and Lung Transplantation in 2015 Inaugural lecture (with the Mayor of Gateshead in attendance) at the University of Northumbria in Newcastle in February 2015. Ong L.P., Chan S., Collins N., Kuravelli S., Clark S.C. Distractions in Cardiac Surgery – Do Interruptions Matter? Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in March 2015 Clark S.C. Invited lecture Current Status of Ex Vivo Lung Perfusion Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in March 2015 Slight R., Bernstein M., Stamenkovic S., Clark S.C., Forty J. First UK Experience of Robotically Assisted Pulmonary Lobectomy with the Da Vinci System Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in March 2015 Ong L.P., Thompson E., Tristan Z., Muse H., Wallace K., Prabhu M., Parry G., Clark S.C. Prolonged Intensive Care Unit Stay after Bilateral Lung Transplantation – Impact on Late Survival, Rejection and Functional Outcomes Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in March 2015 Slight R., Bernstein M., Stamenkovic S., Clark S.C., Forty J. Robotically Assisted Pulmonary Lobectomy ; First Experience with the Da Vinci System (Movie Presentation) Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in March 2015


Clark S.C., Merlo C.A., Arnaoutakis G.J., Yonan N., Thomas D., Simon A., Thompson R.,Thomas H., Orens J., Shah A.S. Effect of Health Care Delivery System on Lung Transplant Outcomes for Cystic Fibrosis – The UK versus the US Presented at the Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in March 2015 Dabak G., Dalar L.,Tasci E., Clark S.C. Lung Transplantation in Turkey – Lessons from Surgeons and Pulmonologists Presented at the 18th Annual Congress of the Turkish Thoracic Society in Belek, Antalya, Turkey in April 2015 Ong L.P., Kuravilli S., Chan S., Collins N., Butt T., Clark S.C. Surgical Distractions during Lung Transplantation – Do they Matter? Presented at the International Society for Heart and Lung Transplantation Annual Meeting in Nice in April 2015 Clark S.C., Ranasinghe A. Workforce Planning for Cardiopulmonary Transplantation in the United Kingdom Presented at the 3rd National CQUIN Meeting for Cardiopulmonary Transplantation in Birmingham in June 2015 G. Niranjan, Mayes J.,Dark J.H., Clark S.C. Bridging to Lung Transplantation using Dual Novalungs in Severe Pulmonary Hypertension. Presented at the 3rd National CQUIN Meeting for Cardiopulmonary Transplantation in Birmingham in June 2015 McMinn J., Wrightson N., Parry G., Clark S.C., Scheuler S., MacGowan G. Who and When to Refer for Advanced Heart Failure? A Survey of Clinicians Referring to the Freeman Hospital Presented at the British Cardiovascular Society in Manchester in June 2015 McElnay P. J., Kenny L., Roysam C., Clark S.C., Dark JH The Risk of Neurological Sequelae following Subclavian Cannulation in Elective Aortic Arch Surgery is Low with Cerebral Saturation, Left Radial Pressure and Left Common Carotid Stump Pressure Monitoring Presented at the Liverpool Aortic Surgery Symposium in Liverpool in July 2015 Clark S.C. Invited lecture Conduits in Coronary Artery Bypass Surgery Presented at the Birmingham Review Course in Cardiothoracic Surgery in Birmingham in September 2015

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Clark S.C. Invited lecture Current Status of Heart Transplantation and Circulatory Support Presented at the Birmingham Review Course in Cardiothoracic Surgery in Birmingham in September 2015 G. Niranjan, Mayes J.,Dark J.H., Clark S.C. The Use of Dual Novalung as a Bridge to Lung Transplantation in a Patient with Pulmonary Hypertension Presented at the European Association for Cardiothoracic Surgery Annual Meeting in Amsterdam in October 2015 Ong L.P., Kuravilli S., Chan S., Collins N., Butt T., Clark S.C. A Novel Surgical Distractions Capture Tool for Cardiac Surgery and Lung Transplantation : Impact of Distractions on Outcomes Presented at the European Association for Cardiothoracic Surgery Annual Meeting in Amsterdam in October 2015 Ong L.P., Thompson E., Tristan Z., Muse H., Wallace K., Prabhu M., Parry G., Clark S.C. Prolonged Intensive Care Unit Stay after Bilateral Lung Transplantation – Impact on Functional, Rejection and Survival Outcomes Presented at the European Association for Cardiothoracic Surgery Annual Meeting in Amsterdam in October 2015


INVITED CHAIRMANSHIPS Clark S.C. Moderator & Meeting Chairman. CABG Surgery : Out of the Box Meeting, Geneva, Switzerland in September 2003 Clark S. C. Chairman - Mechanic Insights into Ischaemia-Reperfusion Session International Society of Heart and Lung Transplantation meeting held in San Francisco in April 2007 Clark S. C. Chairman – Cardiopulmonary Transplantation Session Society for Cardiothoracic Surgery of Great Britain and Ireland meeting in Liverpool in March 2010 Clark S. C. Chairman - Donor Influences on Outcomes after Lung Transplantation Session International Society of Heart and Lung Transplantation meeting held in Chicago in April 2010 Clark S.C. Chairman - Lung Transplantation Session European Association for Cardiothoracic Surgery 24th Annual Meeting in Geneva, Switzerland in September 2010 Clark S.C. Chairman - Primary Graft Dysfunction after Lung Transplantation Session International Society of Heart and Lung Transplantation Annual Meeting in San Diego in April 2011 Clark S.C. Chairman – Perfusion in Lung Disease Session (Postgraduate Day) European Association for Cardiothoracic Surgery Meeting in Lisbon in October 2011 Clark S. C. Chairman – Cardiothoracic Forum Session Society for Cardiothoracic Surgery in Great Britain and Ireland/Association of Cardiothoracic Anaesthetists Combined Annual Meeting in Manchester in April 2012

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Clark S.C. Chairman – Advances in Pulmonary Transplant Surgery Symposium International Society of Heart and Lung Transplantation Annual Meeting in Prague in April 2012 Clark S.C. Chairman – Clinical Aspects of Lung Transplantation Session International Society of Heart and Lung Transplantation Annual Meeting in Prague in April 2012 Clark S.C. Chairman – 25th Anniversary of Paediatric Transplantation Meeting in Newcastle upon Tyne in October 2012

Clark S.C. Chairman – SCTS University Postgraduate Course – Heart Failure Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Brighton in March 2013. Clark S.C. Chairman – Lung Failure Surgery Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Brighton in March 2013. Clark S.C. Chairman – Cardiothoracic Forum Symposium Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Brighton in March 2013. Clark S.C. Chairman – Bridging to Lung Transplantation : Who, When and with What? International Society of Heart and Lung Transplantation Annual Meeting in Montreal in April 2013 Clark S.C. Chairman – Bronchoscopic Battles and Anastomotic Atrocities International Society of Heart and Lung Transplantation Annual Meeting in Montreal in April 2013 Clark S.C. Chairman – Left Ventricular Assist Devices – Long term Support European Association for Cardiothoracic Surgery Annual Meeting in Vienna in October 2013.


Clark S.C. Chairman – Advanced Lung Failure Surgery Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Edinburgh in March 2014. Clark S.C. Chairman – Cardiothoracic Forum Symposium – Extended Practice Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Edinburgh in March 2014. Clark S.C. Chairman – Advanced Heart Failure Surgery Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Edinburgh in March 2014. Clark S.C. Chairman – Mechanical Support Science Session International Society of Heart and Lung Transplantation Annual Meeting in San Diego in April 2014. Clark S.C. Chairman – Developing Nations Session International Society of Heart and Lung Transplantation Annual Meeting in San Diego in April 2014. Clark S.C. Chairman – Young Investigators Scientific Prize Award Session Malaysian Association for Thoracic and Cardiovascular Surgery in Kuala Lumpur in October 2014. Clark S. C. Future Developments Session National CQUIN Meeting for Cardiopulmonary Transplantation in Manchester in November 2014. Clark S.C., Advanced Lung Failure – ECMO and ITU Session Society for Cardiothoracic Surgery in Great Britain and Ireland Annual Meeting in Manchester in March 2015. Clark S.C. Chairman - Emerging Countries Session International Society for Heart and Lung Transplantation Annual Meeting in Nice in April 2015

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Clark S. C. Chairman - Future Developments Session National CQUIN Meeting for Cardiopulmonary Transplantation in Birmingham in June 2015. Clark S.C. Chairman - Coronary Artery Disease and Aortic Valve Intervention Session Newcastle Complex Cardiovascular Intervention LIVE Meeting in June 2015


ACADEMIC EXPERIENCE In 2014 I was appointed as Professor of Cardiothoracic Surgery and Cardiopulmonary Transplantation in Department of Applied Science of the Faculty of Health and Life Sciences at the University of Northumbria in Newcastle. I am also a Clinical Lecturer affiliated with the Institute of Cellular Medicine at the University of Newcastle. I have held this academic post since 2000. Prior to my Consultant appointment I was First Assistant in Cardiothoracic Surgery with the Department of Surgery, University of Newcastle establishing many academic connections and affiliations during that time. In 2001 I received a ‘Pump Priming’ Award from the Royal College of Surgeons of England to undertake research on reperfusion injury after lung transplantation. I have undertaken many invited lectures from learned Societies and Chairmanships at National and International meetings as detailed elsewhere in this Curriculum Vitae. Research I was the local lead for the Evaluation of Ventricular Assist Devices (EVAD) Study in 2006/7. I am the local Principle Investigator for the following national multi-centre NHS portfolio studies :

• Arterial Revascularisation Study (ART). • Transfusion Indication Threshold Reduction Study (TITRE2). • A Randomised controlled trial to investigate the clinical and cost-

effectiveness of adding an ablation device-based MAZE procedure as a routine adjunct to elective cardiac surgery for patients with pre-existing atrial fibrillation (AF) (AMAZE Trial).

• Evaluation of Xience Prime vs Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularisation (EXCEL Study).

• I am a co-investigator in the Ex-Vivo Lung Perfusion (EVLP) Study and the Lost Lung Study, the latter having recently been funded by a grant from NHSBT/MRC.

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Academic Activity for Learned Societies In 2003/4, I was selected to be a reviewer of abstract submissions for the Annual Meeting of the Society for Cardiothoracic Surgery of Great Britain and Ireland. From 2005 I was appointed as the Lead Reviewer in Transplantation on the Program Committee for this meeting, a post I continue to hold leading a team of 5 reviewers of submitted abstracts in cardiac surgery and in transplantation and participating in annual Program Committee meetings at the Royal College of Surgeons of England. In 2007, 2010 and 2014 I was chosen as an abstract reviewer for the International Society of Heart and Lung Transplantation (ISHLT). In 2011 I was chosen to serve on the Program Committee for the 2012 annual meeting of ISHLT to be held in Prague and the subsequent meeting in 2013 in Montreal. I was selected as a reviewer of submitted abstracts for the 2011, 2013 and 2015 European Society of Organ Transplantation annual meetings to be held in Glasgow, Vienna and Brussels. In 2011 I was asked to develop the International and Inter-Society Co-ordination Committee of the International Society of Heart and Lung Transplantation to promote co-operation, education and trouble-shooting activities for transplant units worldwide. This was a result of my involvement with lung transplant programs in Egypt and Turkey on behalf of our Trust. In 2012 this committee (also known as I2C2) came to fruition and now is a major Committee within ISHLT responding to cardiopulmonary transplant related issues around the world, providing a conduit for inter-society activities such as joint meetings and as a facilitator for developing units in countries outside of North America, Western Europe and Australasia. I am now the co-chairman of this Committee with Andreas Zuckermann, a transplant surgeon from Austria with whom I collaborated to develop this concept to fruition from its initial founding principles. I am a Faculty member of the Mentorship Program of the International Society of Heart and Lung Transplantation. In 2013, I was the organizer of the Society for Cardiothoracic Surgery in Great Britain and Ireland University course on Heart Failure Surgery – From Cell to Device. This day long meeting included an eminent International Faculty and preceded the main Annual Meeting of the Society.


In 2013 I was appointed as a member of the Society of Thoracic Surgeons (STS) Workforce on Patient Safety and am the only European member on this predominantly North American committee. I was selected as a reviewer of submitted abstracts for the 2014 and 2015 European Association of Cardiothoracic Surgery annual meetings held in Milan and Amsterdam. Appointed as Chairman of the Anastomotic Dehiscence Group for the Consensus Statement on the Definition of Airway Complications after Lung Transplantation from the Standards and Guidelines Committee of the International Society of Heart and Lung Transplantation in 2014. I was selected as a reviewer of submitted abstracts for the 2015 European Society for Organ Transplantation annual meeting held in Brussels. I am a member of the International Valvular Surgery Study Group (IVSSG) which is a steering group of 17 academic surgeons from 8 countries with expertise in sutureless aortic valve replacement surgery. The group is responsible for monitoring of an international registry, data quality and control and interpretation of the information. The group addresses scientific priorities, analysis and quality. Member of the Steering Group of the European Society for Organ Transplantation Ex Vivo Lung Perfusion Registry from May 2015. As a founding member of this committee we developed this Registry to record European practice in ex vivo lung perfusion, track clinical outcomes and compare perfusion protocols. We developed the clinical governance structures, database fields, corporate and societal sponsorship and development to bring this valuable resource to fruition. Member of the Program Committee for the International Society for Minimally Invasive Cardiothoracic Surgery - 2015

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Professional Examinations In 2002 I was elected to serve on the Court of Examiners for the MRCS examinations with The Royal College of Surgeons of England. I retired from the Court in October 2010 after serving the maximum term and was nominated to become an Assessing Examiner with the Intercollegiate Committee for Basic Surgical Examinations (ICBSE) – a post I began in March 2011 to maintain the highest standards during Intercollegiate MRCS examinations by evaluating both the examination and examiners. From 2003 to 2005 I was a member of the Panel of Examiners for the Intercollegiate MRCS examination (Basic Sciences) with The Royal College of Surgeons of Edinburgh. I was an examiner for MB BS Stage 2 assignments for the Faculty of Medical Sciences, University of Newcastle from 2004 onwards. I have acted as an Examiner for final MB,BS examinations, University of Newcastle from 2009 to date. Educational Roles College Surgical Tutor – Freeman Hospital - from April 2005 to October 2012. I was the Chairman of the Regional Training Committee for 4 years (having been asked to remain in place for an additional year by the Program Director) 2004-2008. Educational Supervisor – For ST1, CT1 and the Peri-CCT National Transplant Fellow (2010). Medical Supervisor for a Surgical Care Practitioner in Cardiothoracic Surgery undertaking a Postgraduate Diploma at Teesside University. Medical Supervisor for the Non-Medical Prescribing Course – University of Northumbria 2009 – 2010. Supervisor for a Nurse Practitioner undertaking an MSc in Advanced Practice in Health and Social Care with the University of Cumbria.


SSC Student Medical Supervisor 2009 to date – one student supervised by me won a Prize from the Royal College of Surgeons of Edinburgh to support her elective for the audit work undertaken under my supervision (on re-admission to cardiac ITU). Her work was also selected for presentation as a poster at the SCTS Annual meeting in 2011. Another student supervised by me won the 2011 SSC Student Poster Prize, University of Newcastle Medical School for our audit of Aspirin administration after cardiac surgery. Organiser of weekly Departmental Educational Meetings with varying cardiac, thoracic and transplant related presentations and Journal Clubs on a rolling program. Faculty member – Bypass, Balloon Pumps and Assist Devices Course – Royal College of Surgeons of England 2006 to 2013. Faculty member – Cardiac Surgical Emergencies Training Day – 2010 to date, Freeman Hospital. British Thoracic Society Lung Transplantation e-Learning Website Video – Speaker on pulmonary transplantation – September 2011. In 2014 I devised and organized the International Surgical Aspects of Cardiopulmonary Transplantation Course held over two days in the Newcastle Surgical Training Centre. This course was the first of its kind in the world and gave surgeons in training didactic teaching and hands on cadaveric surgical training experience in heart and lung transplantation, VAD implantation, ex vivo lung perfusion and ECMO. Delegates attended from the UK, Russia, Germany, Spain, Brazil, Ukraine, Singapore and India. The course evaluated exceptionally well and was run again in 2015. The course received local television and newspaper coverage. Elected as Fellow of the Faculty of Surgical Trainers – The Royal College of Surgeons of Edinburgh – 2015 Faculty member – Birmingham Review Course in Cardiothoracic Surgery – 2015 to date

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Miscellaneous Academic Activity I was appointed as an assessor for applications for the Joint American College of Surgeons/Royal College of Surgeons Research Fellowship in 2002 by the Royal College of Surgeons of England. I am an assessor of research awards for the Scottish Hospital Endowments Research Trust. Assessor of applications for the Research Fellowship Scheme 2006-2008 and 2014 - 2015 for the Royal College of Surgeons of England. Assessor of applications for Hunterian Professorships 2007 for the Royal College of Surgeons of England. Reviewer of Basic Science Grant applications for Heart Research UK 2008 and 2013 I am a reviewer of original research papers for the following peer reviewed journals: The Annals of Thoracic Surgery The Journal of Heart and Lung Transplantation Laboratory Animals Expert Opinion in Pharmacotherapy Journal of Cardiothoracic Surgery Medical and Biological Engineering and Computing Pulmonary Pharmacology and Therapeutics European Journal of Cardiothoracic Surgery Interactive Journal of Cardiovascular and Thoracic Surgery Diabetes and Vascular Disease Research International Journal of Artificial Organs European Journal of Cardiothoracic Surgery The Surgeon – The Journal of the Royal College of Surgeons of Edinburgh Journal of Cardiovascular Surgery Risk Management and Healthcare Policy Transfusion Medicine Journal of Anaesthesia and Surgery I am a book reviewer for the British Medical Journal Medical Book Competition 1998 - 2015. I acted as a chairman for the 1999 British Medical Association medical video competition.


Contributor to Deciding Right (guidance and app) developed by the North England Strategic Clinical Network and St. Oswald's Hospice. This work was supported by NHS England and an NHS Innovations Award. I was involved in developing the end of life guidance for patients being treated with medical devices such as AICDs and VADs. Appointed as a Review Editor for the Nature journal Frontiers in Heart Surgery in 2015. Examiner – PhD Thesis entitled Identification of Heart Donors using Biochemical Markers (V. Dronavalli) for the University of Birmingham in May 2015. Fellow of the Faculty of Surgical Trainers – The Royal College of Surgeons of Edinburgh - 2015

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MANAGERIAL & LEADERSHIP EXPERIENCE Within the Trust Head of Department 2005-2008. Deputy Director of Cardiopulmonary Transplantation from 2010. Acting Director of Cardiopulmonary Transplantation August 2011 to November 2011 Director of Cardiopulmonary Transplantation – January 2012 to date Member of the Cardiopulmonary Transplant Executive. Member of the Institute of Transplantation Clinical Executive Committee. Lead for Quality and Safety in the Department of Cardiothoracic Surgery. In this capacity I have authored a 56 page Departmental Manual of Cardiothoracic Surgery which outlines the organization of the department, gives background knowledge of cardiac and thoracic surgery, details of how to perform common procedures and includes ward protocols. I also developed a full Departmental clinical protocol for all aspects of cardiac and thoracic surgery, unifying patient management protocols for all Consultants to ensure consistency of patient care. This is regularly audited to check for compliance. I developed patient safety checklists for cardiac, thoracic and transplant surgery as well as TAVI which have been adopted nationally and sanctioned by the SCTS and NPSA. Checklists have been endorsed by the European Association for Cardiothoracic Surgery and will be adopted across Europe from September 2011. I also contributed to the guidance from the Heart Improvement Programme – Getting it Right – Improving the Consent Process for Cardiac Surgery – 2007 (www.heart.nhs.uk/consent/casestudies/casestudy1.html) with regard to the patient information sheets I developed and have revised since my appointment. Lead for the Development of the Cardiothoracic Surgery Nurse Practitioner Program. I developed a unique 1 year academic and clinical training scheme and recruited 8 nurse practitioners to provide full time care for ward based patients and the pre-admission clinic. After successful completion of the required clinical competencies and academic courses (including clinical skills course and non-medical prescribing course) this group replaced the junior doctors on our wards from June 2010. The scheme was recognized by winning the SCTS prize for best presentation at the cardiothoracic forum at the 2011 Annual Meeting for an abstract describing the training scheme and its execution.


For the National Health Service Chairman of the Specialist Training Committee – Northern Region 2004-2008 Specialist Advisor for Cardiothoracic Surgery – National Institute for Clinical Excellence 2009 to date – Developed guidance issued on endoscopic vein harvesting for coronary artery bypass grafting, ventricular mechanical assist with the Levitronix Centrimag system and thoracoscopic exclusion of the left atrial appendage in non-valvular atrial fibrillation (with or without other cardiac surgery) for the prevention of thromboembolism. In 2015 I evaluated normothermic ex-vivo preservation of hearts from brainstem dead donors for clinical transplantation. Specialty Programme Director for Cardiothoracic Surgery – Confidential Reporting System for Surgery (CORESS) 2009- to date College Tutor for Cardiothoracic Surgery, Freeman Hospital 2003 to date College Assessor for Consultant appointment committees – The Royal College of Surgeons of England 2009 to date Member of the Reference Committee – General Medical Council – 2009 to date Member of the Program Committee for the Society for Cardiothoracic Surgery in Great Britain and Ireland – Chairman of the Transplantation section 2005 to date Member of the Lung Cancer Peer Review Group – North Zone – 2009 to date Egyptian Lung Transplant Program Advisory Team - lead clinician and surgeon 2009 NHSBT – Heart Transplant Assessment Guidelines Committee – 2010/11 NHS Evidence User Research Panel – 2010 to date Task Force on Surgical Safety Checklists – Clinical Guidelines Committee Member, European Association for Cardiothoracic Surgery – 2010/11 Member of the NHSBT Cardiothoracic Advisory Group

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Author - National Standards for Cardiothoracic Organ Retrieval Training – March 2011 Member of the CTAG Working Party – Increasing Heart and Lung Donation in the United Kingdom – July 2011 Istanbul (Turkey) Lung Transplant Program Advisory Team - Surgical Advisor – 2011 National Institute for Health Research Health Technology Assessment Programme Expert Reviewer 2011 to date. In this role I have reviewed evidence and given opinions on surgery for atrial fibrillation, ultrasound monitoring of endovascular stent leaks and management of aortic transection. Member of the NIHR Evaluation, Trials and Studies Co-ordinating Centre (NETSCC) College of Experts and reviewer of proposals for commissioned research for the NIHR Health Services and Delivery Research Programme. In 2013 I evaluated proposals for avoiding mortality from in-hospital cardiac arrest.

Guideline Development Group on Idiopathic Pulmonary Fibrosis for the NHS National Institute for Health and Clinical Excellence – 2011. The National Clinical Guideline Centre, hosted by the Royal College of Physicians, was commissioned by NICE to develop an evidence-based clinical guideline on the diagnosis and management of suspected idiopathic pulmonary fibrosis, including pulmonary transplantation. I was selected competitively as the co-opted expert onto this committee as a thoracic and pulmonary transplant surgeon. In this role I advised the panel on the aspects of the guideline related to ventilation, mechanical respiratory support with ECMO or Novalung and the role of lung transplantation.

Member of the Lung Allocation Working Group for NHSBT in July 2013

Member of the Council of the North of England Medico-Legal Society – 2012. Member of the Clinical Reference Group for Heart and Lung Transplantation (Adult and Paediatric) for the NHS Commissioning Board 2013 until its closure in March 2015. Within this group I was the lead for Commissioning for Quality and Innovation and also led the CRG submission for mechanical bridging to lung transplantation. Member of the Institute for Leadership and Management – 2013 to date.


Selected competitively by NHSBT as Deputy Chair of the Cardiothoracic Advisory Group (with special responsibility for pulmonary transplantation) in July 2013. Member of the Faculty of Medical Leadership and Management – 2013 to date Member of the Novel Technologies for Organ Transplantation Steering Group 2013/14 Course Organizer and Faculty member of the Cardiothoracic Transplantation section of the NHSBT/British Transplantation Society Organ Retrieval Masterclass at Oxford University 2013 to date. Organizer – Commissioning for Quality and Innovation in Adult Cardiopulmonary Transplantation Meeting held in Newcastle in the Institute of Transplantation in January 2014 bringing all transplant units together in the UK for the first time to discuss practice, outcomes, patient experience and activity. I have subsequently been asked to lead the CQUIN process in cardiopulmonary transplantation nationally through the Clinical Reference Group. Member of the Specialty Advisory Committee in Cardiothoracic Surgery for the Joint Committee on Surgical Training (JCST) – Appointed in 2014 for a five year term. Appointed to the Board of Review of the National Organ Retrieval Service (NORS) in 2014, commissioned by NHSBT to ensure that the service can meet the requirements of the organisations 2020 strategy. The aim of the review is to benchmark the current service, identify shortfalls and make recommendations to ensure equity, timeliness, flexibility and value for money in the context of future activity projections. Appointed to the Northern England Clinical Senate Assembly in 2014 as a member. Appointed as an Associate Advisor in Cardiac Surgery for the Parliamentary and Health Service Ombudsman in 2014. Appointed as a Clinical and Professional Advisor to the Care Quality Commission in 2014 after competitive interview. Member of the Perceval Sutureless Valve Steering Committee from June 2014. NICE Advisory Committee Member for the Surveillance Review of the CG163 2011 Idiopathic Pulmonary Fibrosis Guideline in March 2015.

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Peer Reviewer for Cardiopulmonary Transplantation Services for NHS England – 2015 NORS Training and Certification Committee of NHS Blood and Transplant – 2015 Nominee – Newcastle upon Tyne Hospitals NHS Foundation Trust Personal Touch Award - 2015

Chairman – Sri Lanka Society for Heart and Lung Transplantation – 2015 to date Elected as a Fellow of the Faculty of Surgical Trainers – The Royal College of Surgeons of Edinburgh – 2015 Nominated in 2015 by the Society of Cardiothoracic Surgeons of Great Britain and Ireland to act as a Specialist Adviser to NICE’s Interventional Procedures Programme considering normothermic ex-vivo preservation of hearts from brainstem dead donors for clinical transplantation Author – Cardiopulmonary Transplantation chapter for the SAC and SCTS Cardiothoracic Surgery UK Workforce Report 2015


INNOVATION Mechanical Proximal anastomosis devices 2005 – largest personal experience in the UK with these devices. TAVI – joint lead cardiothoracic surgeon 2009 to date VAD – joint lead cardiothoracic surgeon 2005 First surgeon in the UK to implant the Micromed Debakey VAD. Minimally invasive AF surgery – joint lead cardiothoracic surgeon since 2009 First surgeon in the UK to perform bilateral thoracoscopically assisted Bauer MAZE operation. Ex Vivo Lung Perfusion - member of the research group since 2009 Lung transplantation from non heart beating lung donors First surgeon to implant lungs from a DCD donor in the UK. First case of minimally invasive mitral valve repair in Newcastle. Part of the surgical team to perform the first ever robotically assisted thoracic surgery in the UK. I was the operating surgeon for the first two cases ever performed. Sutureless aortic valve replacement. SUB-SPECIALTY SPECIALISED SKILLS

Transcatheter aortic and mitral valve implantation, Valve in Valve implantation Mitraclip Edwards Intuity and Sorin Perceval sutureless aortic valve implantation Da Vinci robotic pulmonary lobectomy Convergent MAZE surgery Minimally invasive mitral valve repair/replacement (Endoclamp)

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MEDIA WORK I have been interviewed by the following media organisations in relation to cardiothoracic surgery and transplantation : Northern Echo newspaper BBC Look North BBC News 24 Sky News Radio 5 Live BBC Scotland


PROFESSIONAL COURSES ATTENDED

Advanced Cardiac Life Support (ACLS) was obtained during an elective period at the New Britain Regional Trauma Centre, Connecticut, USA, in May 1989. The Radiation Protection Course was undertaken at The National Heart and Lung Institute, Chelsea, in 1991. Advanced Trauma Life Support Provider Course (ATLS) was completed at the Northern General Hospital, Sheffield, in July 1993. As a result of my performance on this course, I was recommended to the Royal College of Surgeons of England for training as an ATLS Instructor. Animals (Scientific Procedures) Act 1986 Personal Licence Course and examination was completed in September 1994. Animals (Scientific Procedures ) Act 1986 Anaesthesia and Surgery (Module 4) Course and examination was completed in August 1996. Animals (Scientific Procedures) Act 1986 Project Licencees Course (Module 5) and examination completed in December 1996. Care of the Critically Ill Surgical Patient Instructors Course held at The Royal College of Surgeons of England in London in January 2001. Training the Trainers Course held by The Royal College of Surgeons Of England in Newcastle upon Tyne in May 2001. Clinical Research Methods for Surgeons Course held at the Royal College of Surgeons of England. Court of Examiners Induction and Training Course held at the Royal College of Surgeons of England in April 2002. Good Practice and Recruitment and Selection Course held in February 2003 Advanced Communication Skills Course held in January 2010 which is mandatory for all lung cancer MDT meeting core members.

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SOCIETY MEMBERSHIP

Society of Cardiothoracic Surgeons of Great Britain and Ireland

The International Society for Heart and Lung Transplantation European Association for Cardiothoracic Surgery

British Thoracic Oncology Group

Society of Thoracic Surgeons – International Member Association of Aviation Medical Examiners Royal Aeronautical Society North of England Medico-Legal Society Institute for Leadership and Management British Transplantation Society International Society for Minimally Invasive Cardiothoracic Surgery European Society for Organ Transplantation European Cardiothoracic Transplant Association

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