Robert G. Martin, MD Robert G. Martin, MD Donald R. Sanders, MD, PhD Donald R. Sanders, MD, PhD

Following Implantation of 4 Foldable Lens Designs

Following Implantation of 4 Foldable Lens Designs

Higher Order Aberration

Higher Order Aberration

Study ObjectiveStudy Objective

Objective Of The Study Was To Determine If Implantation Of Different Foldable Lens Designs Resulted In Different Amounts Of Higher Order Aberrations

Objective Of The Study Was To Determine If Implantation Of Different Foldable Lens Designs Resulted In Different Amounts Of Higher Order Aberrations

Study DesignStudy Design

Patients Had Tracey VFA Performed On Eyes To Undergo Cataract Extraction

Patients Were Randomly Assigned To Receive 1 Of 4 Foldable Lens Designs

Tracey VFA Was Repeated At 1 Week Postoperatively

Patients Had Tracey VFA Performed On Eyes To Undergo Cataract Extraction

Patients Were Randomly Assigned To Receive 1 Of 4 Foldable Lens Designs

Tracey VFA Was Repeated At 1 Week Postoperatively

Pupil SizePupil Size

All pre and postoperative measurements of higher order aberrations were done with a 4.5mm pupil size

All pre and postoperative measurements of higher order aberrations were done with a 4.5mm pupil size

Foldable Lens DesignsFoldable Lens Designs

STAAR Collamer

STAAR Plate Haptic Silicone

ALCON SA-60

AMO Sensar

STAAR Collamer

STAAR Plate Haptic Silicone

ALCON SA-60

AMO Sensar

Preoperative Total Higher Order (HO) Aberrations

Preoperative Total Higher Order (HO) Aberrations

No Significant Difference Between IOLs

0.330.31 0.32

0.29

0

0.1

0.2

0.3

0.4

RM

S V

alu

e

StaarCollamer

Staar Plate Alcon SA60 AMO Sensar

One-Week PostoperativeTotal Higher Order (HO) Aberrations

One-Week PostoperativeTotal Higher Order (HO) Aberrations

Collamer significantly better than STAAR plate and Alcon SA-60 (p< 0.005)Collamer significantly better than STAAR plate and Alcon SA-60 (p< 0.005)

0.6

0.93

1.281.13

0

0.2

0.4

0.6

0.8

1

1.2

1.4

RM

S V

alu

e

StaarCollamer

Staar Plate Alcon SA60 AMO Sensar

N = 21 N = 24 N = 19 N = 16

Collamer IOLCollamer IOL

Collamer Had Significantly Less HO Aberrations Than STAAR Plate And SA-60 (P 0.005).

Difference With Sensar Was Not Significant.

Collamer Had Significantly Less HO Aberrations Than STAAR Plate And SA-60 (P 0.005).

Difference With Sensar Was Not Significant.

NoteNote

Sample size may be too small, especially with the Sensar group, and results could change with a larger sample. However, we have strong clinical indications that less higher order aberrations are induced with the Collamer lens as compared to plate lenses and AMO lenses.

Sample size may be too small, especially with the Sensar group, and results could change with a larger sample. However, we have strong clinical indications that less higher order aberrations are induced with the Collamer lens as compared to plate lenses and AMO lenses.

Pre-op – Average H.O. AberrationsPre-op – Average H.O. Aberrations

STAAR Collamer

Alcon SA-60

STAAR Plate

AMO Sensar

Postop – Average H.O. AberrationsPostop – Average H.O. Aberrations

STAAR Collamer

Alcon SA-60

STAAR Plate

AMO Sensar

SummarySummary

Three Other Foldable Lenses Tested Had Between 55% and 117% More Higher Order Aberrations at 1 Week Postoperatively than the STAAR Collamer IOL

Three Other Foldable Lenses Tested Had Between 55% and 117% More Higher Order Aberrations at 1 Week Postoperatively than the STAAR Collamer IOL

This Is A Study Of Optical AberrationsThis Is A Study Of Optical Aberrations

Is it clinically significant? Is this especially significant in

patients with large pupils? Do we need a bigger implant? Do we need a different shaped

lens? Do we need a different edge? Do we need a different material?

Is it clinically significant? Is this especially significant in

patients with large pupils? Do we need a bigger implant? Do we need a different shaped

lens? Do we need a different edge? Do we need a different material?Robert G. Martin, MD Robert G. Martin, MD Donald R. Sanders, MD, PhD Donald R. Sanders, MD, PhD