rheumatic heart disease.docx
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Rheumatic Heart Disease
Rheumatic Heart Disease caused by recurrent episodes of rheumatic fever; characterized by
changes in the myocardium or scarring of the heart valves that reduce the power of the heart to
pump blood
Rheumatic fever principally involves the heart, joints, CNS (Central Nervous System),
skin, subcutaneous tissues.
The term Rheumatic heart disease refers to the cardiac involvement develops to 50% of
patients and may affect the endocardium, myocardium or pericardium. It may later affect
the heart valves, causing chronic valvular disease.
The extent of damage to the heart depends on where the disorder strikes.
Causative Factors
• GABS (Group A Beta- Hemolytic Streptococci)
• Rheumatic fever
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Signs and Symptoms
• Poly arthritis- sharp, sudden pain starts over sternum and radiates to neck, shoulders,
back and arms.
• Erythema marginatum- a non- pruritic, muscular, transient rash.
• Subcutaneous nodules- a firm, movable, nontender and about 3 mm-2 cm in diameter.
• Transient chorea- involuntary grimace and an inability to use skeletal muscles in a
coordinated manner.
• Heart murmur
• CHF
Laboratory and Diagnostic Test
There is no diagnostic studies are specific for rheumatic heart disease, but the following can support the
diagnosis:
• WBC count and ESR is elevated
• C- reactive protein is positive.
• Cardiac enzmes levels may increase in severe carditis.(Creatine Kinase and Troponin)
• Anti streptolysin- O titser is elevated 95% of patients with in 2 months onset.
• Throat cultures continue to presence of GABS; however they usually occur in small
numbers. Isolating them is difficult.
• ECG reveals no diagnostic changes, but 20% of patient show a prolonged PR interval.
• Echocardiography helps evaluate valvular damage, chamber size, ventricular function
and the presence of a pericardial effusion.
• Cardiac catheter evaluates valvular damage and left ventricular function in severe cardiac
dysfunction.
Treatment
Severe mitral or aortic valve dysfunction that causes persistent heart failure requires corrective surgery
such as:
• Commissurotomy
• Valvuloplasty
• Valve replacement
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Valve Replacement