research and creative accomplishments symposium...welcome to the 2016 research and creative...

Research and Creative

AccomplishmentsSymposium

WEDNESDAY, APRIL 20, 2016

1

An Expression of Gratitude from the Associate Vice President for Academic Affairs

Dear Guests,

Welcome to the 2016 Research and Creative Accomplishments Symposium at Fairfield University. In collaboration with the 16th Annual Sigma Xi Poster Session and the Senior Nurses Capstone Presentations, we have an extraordinary day planned on campus. These events showcase student research and creative projects mentored by our distinguished faculty and represent an important moment of celebration of our students’ commitment to academic excellence.

At today’s series of events, we feature the scholarly work of over 200 undergraduate and graduate students from almost every discipline on campus. The 2016 Research and Creative Accomplishments Symposium feature posters, performances and other creative works that celebrate the vibrant spirit and intellectual vitality of our student body. Whether working individually or in concert with others, the works and projects on display also highlight the importance of Fairfield University’s Jesuit mission and identity to promote scholarship through service. We invite you to enjoy speaking to our talented students about their many academic accomplishments.

For helping organize the 2016 Research and Creative Accomplishments Symposium, I would like to thank members of the Fairfield University community who generously contributed their time and expertise to make this event a success. Special recognition goes to Carolyn Arnold, Sara Colabella, Shannon Gerry, Frances Levine, Lisa Nagy, Deborah Matthews and the dozens of faculty who worked closely with our student presenters throughout the academic year. And of course, we especially thank the students who inspire us every day with their joy for learning.

Congratulations to the student presenters and their faculty mentors. Thank you dear guests for joining us on this day of celebration!

Mary Frances MaloneAssociate Vice President for Academic Affairs

Research and Creative Accomplishments Symposium

WEDNESDAY, APRIL 20, 2016

Graduate and Undergraduate Research Poster Session

9:30 a.m. - 12:30 p.m., BCC Oak Room

16th Annual Sigma Xi Student Poster Session 3 p.m. - 5 p.m., Oak Room

Senior Nurses Capstone Presentation 5 p.m. - 7 p.m., BCC Lower Level

Scholarship and Independent Projects

Many scholarship students will present at Sigma Xi. Please note this information in their individual abstracts.

Wireless System for Monitoring Domestic Appliance Energy ConsumptionUndergraduate: Blanca Aca-Tecuanhuehue ’16, Luis Antunez ’16, Timothy Dessureau ’16, Egnon Locoh ’16Abstract: This project addresses the need to conserve energy in households due to the rising costs of energy. To assist households with energy management, a device will be developed to monitor energy usage. The device will transmit the energy usage from an electrical socket to a mobile device. This project will focus on monitoring the daily consumption of domestic appliances via a smartphone application, to study energy usage behavior by providing visual graphs of each appliance’s daily consumption. This application will provide a visual representation of each appliance’s daily consumption. By visualizing, understanding and comparing graphs of current and past usage, users can easily make smart decisions about their usage. A study of energy consumption awareness was conducted using commercially available products to project how much would be saved by the usage of the product.

Scholarship: HardimanEngineering Senior Design

Faculty Mentor: Professor Uma Balaji

Prosthetic Hand Multi-Tool AttachmentUndergraduate: Chris Babcock ’16, Tom Daniello ’16, Tom Lucakovic ’16, Mike Nagy ’16 (Presenting at Sigma Xi)Abstract: After losing their hand, most of the general public is provided a prosthetic that has a hook on the end, making simple everyday tasks more complicated than they need to be. Previously designed tools involved removing the hook and directly attaching a number of specifically designed tools for each individual task. Although every prosthetic arm is custom fit to the user, our tool provides a universal fit, allowing attachment onto all prosthetic arms, regardless of size, type, and customization, without removal of the main hook component. Through various design iterations and feedback analyses, the final design has four tools: a flashlight, a fork, a smart phone stylus, and a shopping bag carabiner. Tools lock into the optimal ergonomic position for use. The central housing design provides easy conversion from left-handed to right-handed use. Our final prototype is a combination of 3-D printed base, with manufactured metal tools and spring assembly.

Scholarship: LawrenceEngineering Senior Design

Faculty Mentor: Professor James Cavallo

Synthesis and Characterization of Symmetric and Asymmetric Water Soluble Zinc(II) Model Complexes for Liver Alcohol DehydrogenaseUndergraduate: Nicholas Bernier ’16 (Presenting at Sigma Xi)Abstract: Liver alcohol dehydrogenase (LADH) is a zinc metalloenzyme that catalyzes the oxidation of alcohols to aldehydes and ketones and the reduction of a ketone or an aldehyde to an alcohol. Crystallographic data shows the resting enzyme has a zinc(II) metal center which is pseudo-tetrahedrally ligated with one N-histidine side chain, two S-cysteine side chains, and one water molecule. Our work involves the syntheses as well as NMR spectroscopic characterizations of novel water-soluble tridentate pincer ligand precursors. Our work also involves the syntheses, NMR spectroscopy, and electrospray mass spectrometry characterizations of both symmetric and asymmetric potential functional models of the zinc active site in LADH. We model the zinc active site using a family of tridentate pincer ligands coordinating S,N,S donor atoms. A detailed description of the syntheses and characterization of the ligand precursors and model complexes will be presented.

Scholarship: LawrenceChemistry Research and Seminar

Faculty Mentor: Professor John Miecznikowski

Tabletop Micro Patterning DeviceUndergraduate: Ryan Brown ’16, Noel Laflamme ’16, Gabriel Schrier ’16, Michael Valvano ’16 (Presenting at Sigma Xi and morning session)Abstract: Micro patterning is being done through processes of photo or soft lithography. These processes are typically conducted in closely monitored locations such as clean rooms. Since a clean room is expensive to set up, places such as labs and universities have a hard time suiting their needs to micro pattern. The aim for our project was to build a small tabletop micro patterning device that will fulfill the same outcomes as the above methods, but in a less costly and resource intensive way. This device will be about a square foot in area and will be portable, allowing the user to have it on a table, classroom, or even the international space station if needed. The device will consist of a press plate containing the master mold, which will be used to imprint the micro pattern onto a silicone substrate.


Faculty Mentor: Professor Sriharsha Sundarram

2 3

Analyzing Morphometry and Orientation of Loggerhead Sea Turtle HatchlingsUndergraduate: Layra Cintron Rivera ’16, Jessica Romeo ’16, Robert Schwartz ’16 (Presenting at Sigma Xi)Abstract: Loggerhead sea turtles (Caretta caretta) are a threatened species and are particularly vulnerable in the state of Rio de Janeiro, Brazil due to extensive coastal development. We examined orientation cues in loggerhead hatchlings and the potential association of morphometrics with their ability to successfully emerge from eggs and nests. We tracked hatchlings with GPS during their first minutes at sea to determine the relative influence of wave action, light, and magnetic fields on orientation behavior through the surf zone and open ocean. Contrary to past studies, it was observed that light may be the most important orientation cue in their first minutes at sea. We also compared morphometric measurements between hatchlings that were able to emerge and not emerge from their nests. We identified significant differences in carapace width and head length between these hatchling turtles suggesting that some aspects of morphometry potentially correlate with emergence ability.

Scholarship: LawrenceBrazil Zoology Field Experience

Faculty Mentor: Professor Ashley Byun

Improving Nutrition and Access to Healthy Foods: an Evaluation of a Community Based PartnershipUndergraduate: Anna Cruz ’16, Hang Tran ’16 Abstract: More than one third of U.S adults are considered obese and childhood obesity has more than doubled in the past 30 years. Heart disease is now the leading cause of death worldwide, with obesity considered a major contributor. Nutrition has a significant influence on obesity; especially within inner-cities where access to healthy food is often limited. Our project was to evaluate the experience of inner-city families who participated in educational nutrition workshops associated with a food distribution program. Focus groups were used to assess participant perspectives about the program. A total of five sites received the nutrition program and there was one focus group held at each site. Main ideas derived from the focus groups were participant satisfaction with money saving suggestions, ideas for how to make healthier choices and excitement about opportunities to receive foods that they would not normally buy.

Scholarship: CorriganNursing Research

Faculty Mentor: Professor Jessica Planas

Synthesis and Characterization of Self-Assembling NucleopeptidesUndergraduate: Kimberly DelBianco ’17, Samantha Schrecke ’17 (Presenting at Sigma Xi)Abstract: In the complex environment of cells, biomolecular structures have evolved a delicate balance between stability and dynamic responsiveness. Both of these factors rely on the strength and diversity of non-covalent interactions. In an effort design more responsive biomaterials, we have integrated the recognition elements of nucleic acids with self-assembling peptides. Herein, we report the synthesis of guanosine modified short peptides (nucleopeptides) and the characterization of the resulting supramolecular structures assembled in various conditions. Infrared spectroscopy (IR) was used to identify the major secondary structures, G-quartets and extended b-sheet formations, while Atomic Force Microscopy (AFM) was used to image the supramolecular fibers that form. Information from these self-assembling nucleopeptide studies will extend current strategies for “bottom-up” control of final morphology.


Faculty Mentor: Jillian Smith-Carpenter

FT-IR Spectroscopy, Computational Quantum Chemistry, and Hessian Reconstruction Analyses of Helical Peptide Isotopologues of AibUndergraduate: Jesse Dickovick ’16, Chase Foster-Spence ’16, Matthew Rotondaro ’16 (Presenting at Sigma Xi)Abstract: The Amide I vibrational band, in the carbonyl region of the mid-infrared, is known to be diagnostic of protein and peptide secondary structure. The sensitivity of the Amide I band to secondary structure requires a delocalization of Amide I normal modes among several C=O oscillators. We have investigated coupling in helical peptides through a combined experimental and computational approach. Our experiments employ isotope-edited FT-IR spectroscopy, where we have strategically enriched specific amide oscillators with C-13, shifting the Amide I band to frequencies below the broad Amide I envelope, revealing details of inter-amide coupling. We have performed DFT-based quantum mechanical calculations with fixed dihedral angles and C-13 isotopic substitution for identification of Amide I normal mode frequencies and inter-amide coupling constants. DFT results were analyzed with Cho’s method of Hessian reconstruction to calculate local mode frequencies and inter-amide coupling constants.

Scholarship: Lawrence; Corrigan Chemistry Research and Seminar

Faculty Mentor: Professor Matthew Kubasik

Solvent Mediation of Unimolecular Helical Exchange Dynamics in the Synthetic Helical Peptide Z-Aib6-b-Ala-OMeUndergraduate: Jesse Dickovick ’16, Chase Foster-Spence ’16, Matthew Rotondaro ’16 (Presenting at Sigma Xi)Abstract: Our work characterizes the effects of solvent viscosity, polarity, and hydrogen-bonding capacity towards determining the rates of helical conformational exchange of a dissolved solute probe. Our work employs Z-Aib6-b-Ala-OMe, unique for its helical structure and its ability to undergo isoenergetic conformational exchange between left- and right-handed helices. We use 1H and 13C NMR spectroscopy to determine the rates of conformational exchange using line-shape analysis. We vary solvent viscosities by using a series of solvents and by varying sample temperature. Obtained rate constants are analyzed with Eyring treatments to characterize activation thermodynamics. We interpret the kinetic data with theories that admit an explicit role for solvent viscosity, such as Kramers’ theory. Our unique peptide probe undergoes millisecond activated barrier crossings in its electronic ground state. This work provides novel insight into solvent influence in helical exchange dynamics in a unique synthetic polyamide system.

Scholarship: Lawrence; Corrigan Instramental Analytical Lab


Connecting Medical Spanish to the Community: Fairfield University’s Pilot ProgramUndergraduate: Shauna Dresel ’17Abstract: There is a trend in language classes and funding opportunities to promote language learning for the professions. Due to a growing need for bilingual and intercultural competency for health professionals, Dr. Michelle Farrell piloted a course, “Career Spanish for Nursing and Health Studies,” which included a crucial service-learning component to reflect the realities of the health professions and community partnerships and Fairfield’s mission to service learning. Dr. Farrell and I explore the benefits and challenges of providing this type of language course. I additionally shared my perspective, having completed this pilot course, as well as discuss the future needs for my nursing student community.

Scholarship: HardimanCareer-Oriented Spanish: Nursing/Health Studies

Faculty Mentor: Professor Michelle Leigh Farrell

Antimicrobial Activity of Bacterial Isolates from Crassostrea virginica and Black Rock Harbor’s Water Column on Escherichia coli and Bacillus subtilis GrowthUndergraduate: Cathryn Duemmler ’16, Meghan Warchol ’16 (Presenting at Sigma Xi)Abstract: Crassostrea virginica associated bacteria and water column organisms were used in a primary screen to test for the production of antibacterial compounds against tester strains of Escherichia coli (gram-negative) and Bacillus subtilis (gram-positive). Fourteen (A-N) isolates of bacteria were purified and determined to be either gram-positive or gram-negative. Individual isolates plated on marine agar were grown for seven days and subsequently UV treated. Tester strain cultures were suspended in soft agar and plated over the individual inactivated bacteria isolates. Growth inhibition was checked and results indicate that isolates G, H, and M did not inhibit growth of E.coli and B. subtilis. Isolates B and C appeared to reduce E. coli and B. subtilis growth. Isolate N reduced E. coli growth and inhibited B. sub growth. The diminished growth of tester strains by some oyster and water column bacteria suggests that these bacteria may contribute to antimicrobial protection against pathogenic bacteria.

Scholarship: LawrenceBiology Research

Faculty Mentors: Professors Diane Brousseau and Phyllis Braun

Medical SpanishUndergraduate: Ariana Fernandez ’18Abstract: The project consists of researching the demand of Spanish interpreters in the medical field and the requirements to become a medical interpreter. Also, we aim to discover what higher education institutions in the Connecticut-New York area offer medical Spanish courses, what level these courses are offered in and what materials are used, in order to determine how effective and beneficial such courses are in preparing students to assist the increasing Spanish-speaking population in the United States.

Scholarship: Corrigan Independent Research

Faculty Mentor: Professor Michelle Leigh Farrell

Fairfield University Campus GardenUndergraduate: Justine Ferrara ’18, Michelle Pleban ’16Abstract: The Fairfield University Campus Garden is a 3,000 square foot garden that is maintained by students, faculty, and staff. We follow organic practices and grow a variety of produce including: carrots, cherry tomatoes, kale, squash, basil, cilantro, and perennial herbs. Harvest goes directly to the campus cafeteria, Jesuit Community Center, Fairfield University’s Catering Department, and the local food pantry. This poster and related materials will showcase some of the things that the garden is growing and the pests and diseases we have encountered along the way.

Biology Independent ResearchFaculty Mentor: Professors Jennifer Klug and Tod Osier

4 5

Willingness to Pay for Sanitation ServicesUndergraduate: Olivia Fox ’16 Abstract: I am addressing the factors and willingness to pay behind why (or why not) households in poor rural areas invest in proper sanitation disposal devices. Poor sanitation practices and inadequate sanitation devices such as flushing toilets are one of the three major causes behind the current global water epidemic. This particular problem is dominant in developing nations who depend on local rivers, lakes and other fresh bodies of water for drinking water. 663 million people worldwide lack access to clean drinking water, whereas 2.4 billion people do not have access to toilets. Today more people own a cell phone than a toilet. By measuring 556 rural households’ willingness to pay for sanitation services in Quiche, Guatemala, it will allow powerful organizations such as UNICEF to decide how they should tackle the issue, and the people they should target to promote more widespread sanitation.

Water Research SeminarFaculty Mentor: Professor Jo Yarrington

Whistling Wonder: Are Mating Calls Influenced by Body Size in Leptodactylus fuscus?Undergraduate: Ryan Fritz ’17, Sean Thomas ’17 (Presenting at Sigma Xi)Abstract: Whistling Frogs (Leptodactylus fuscus) are named for their distinctive, high-pitched mating calls. For the human ear, these calls appear to be uniform in pitch and length, regardless of the calling individual. However, a spectrogram analysis of the sounds reveals a range of variation in both frequencies and duration of the calls. It is unknown whether this variation has any significance — it could be related to the frogs’ bodily dimensions and fitness. The spectrogram also reveals a “whimper” call that is more infrequent than standard calls and has a smaller frequency range. Latent characteristics of these calls could make certain males more appealing to females. Actively calling males from a population of Whistling Frogs from the União Biological Reserve in Brazil were recorded before being captured, weighed and measured for body length. Data were analyzed to assess whether call quality is associated with larger body dimensions and indicative of fitness.



“We Need Excitement!” vs. “We Need Comfort”: The Relation of Positive and Negative Empathy to Different Relationship Goals in Close RelationshipsUndergraduate: Mary Gaughan ’16, Deanna Martinelli ’16, Jennifer Mezzapelle ’16, Jaqueline Orlandi ’16 (Presenting at Sigma Xi)Abstract: The present study explores the relationship between positive and negative empathy and social motivations within romantic relationships. We expected that positive empathy, which entails strong identification with others’ positive emotions, would relate to a motivation to approach growth and excitement in relationships. In contrast, we expected that negative empathy, which entails strong identification with others’ negative emotions, would relate to a motivation to avoid conflict and anxiety in relationships. To test these hypotheses, we measured participants’ levels of positive and negative empathy, as well as a number of indicators of their relationship-related approach and avoidance motivations (e.g., what kinds of goals do they have for their relationships? Do they encourage their partners to “take chances” to grow or to “play it safe?”).

Results showed a clear relationship between positive empathy and approach motivations, as well as a relationship—albeit a weaker one—between negative empathy and avoidance motivations.

Scholarship: LawrencePsychology Supervised Research

Faculty Mentor: Professor Michael Andreychik

MedispenseUndergraduate: Austin Hliboki ’16, Cameron Sayles ’16, Haasim Vahora ’16, Kevin Zwick ’16 (Presenting at Sigma Xi)Abstract: For our senior design project, our group designed a universal medicine dispensary system for use by patients who are susceptible to improper medication. Both over-medication and under-medication are serious and life threatening issues that many patients who suffer from Alzheimer’s or dementia are prone to. Our goal is to design a prototype system that will store, dispense, and keep track of medications with as little effort from the patient as possible in order to reduce these risks and improve their lives overall. The prototype will use a vacuum arm to suction the proper medication and fulfill the patient’s subscription as well as use a variety of methods to alert them that their medication is ready. The device will be exact and secure to eliminate any possibility of the patient over-medicating and use the multi-layer alert system to ensure that the patient has taken the medication.


Faculty Mentor: Professor Ryan Munden

Gun Violence, Control, Prevention and Intervention in the United StatesGraduate: Sarayu Iyengar ’18Abstract: Gun violence is ubiquitous to the United States (U.S.) society surrounding immense debate and gun control policies. About 30,000 deaths occur annually in the U.S. due to gun violence. This project focuses on the gun culture and control policies found in the U.S. especially in Connecticut (CT). On one hand, the state and federal laws posit the possession of guns as an individual’s constitutional right to defend oneself; contrastingly gun control policies are selectively focusing on certain populations who are at risk for violence. Factors including family, environment, school and mental illness have been cited as contributors to this epidemic. Studies have shown that implementation of stringent gun control laws and background checks have reduced the incidents of gun violence, particularly in CT. In conclusion, this poster makes recommendations for violence prevention strategies and interventions that could be implemented by counselors in addition to advocacy. Professional Issues in Counseling

Faculty Mentor: Professor Tracey Robert

Nursing Management Regarding Neonatal Abstinence SyndromeUndergraduate: Jenna Kelley ’16, Lindsay Klemm ’16Abstract: Approximately 400,000-440,000 infants (10-11%) are exposed in utero to alcohol, tobacco, and/or illicit drugs each year. Neonatal abstinence syndrome (NAS) results from maternal substance use during pregnancy and is a growing problem throughout the U.S. with 21,732 neonates diagnosed annually. When separated from the placenta at birth, the newborn begins to experience withdrawal. The NICU nurse identifies the substance(s) that the mother used during pregnancy, as well as initiates the Finnegan Scoring System. This system is used to monitor the newborn for withdrawal symptoms, and based on these findings, care of the newborn is determined. Nursing care of these newborns requires precise interventions, ranging from pharmacological care to supportive care.

Scholarship: LawrenceTransition to Professional Nursing

Faculty Mentor: Professor Jenna LoGiudice

Coteries in Crisis- Do Black-tailed Prairie Dogs Compete for Resources in Captivity?Undergraduate: Megan Kirkpatrick ’17, Sean Thomas ’17 (Presenting at Sigma Xi)Abstract: Black-tailed Prairie Dogs (Cynomys ludovicianus) are known for establishing tight familial bonds known as coteries. In the wild, coterie formation hardly depends on space, but rather on hierarchical behavior, resource availability, and population density. However, the colony of black-tailed prairie dogs at Connecticut’s Beardsley Zoo faces different obstacles: space is likely the most critical limitation on their social development. Being surrounded on all sides by impenetrable concrete barriers places social pressure on the population. We have monitored this colony for two years through routine surveillance and an automated smoke machine to detect burrow connections in order to better understand the population dynamics and behavior of the colony. Signs of aggression, such as individuals with scarring and injuries, are still present despite adjustments in food placement. Various experiments involving the smoke-machine mapping, video camera traps, and dyed nesting material all seek to verify the presence of rival coteries.

Scholarship: LawrenceVertebrate Zoology Lab


Complementing Electrochemical Studies of Self-Organized Gold Nanoparticle~Cytochrome c Superstructures with UV-Visible SpectroscopyUndergraduate: Nina Kosciuszek ’17 (Presenting at Sigma Xi)Abstract: The addition of the protein, cytochrome c (cyt. c), to gold nanoparticles in solution results in self-organization of cyt. c into multilayered protein superstructures (abbreviated as Au~cyt. c superstructures) and stabilizes the thousands of organized cyt. c proteins to unfolding both when encapsulated in porous solids and when remaining in solution. Our research has shown that the electrochemical characteristics of superstructure-assembled cyt. c are enhanced compared to cyt. c alone. In order to determine whether the enhanced electrochemical properties are directly related to multiple protein layers staying intact at the electrode surface, protein superstructures were stripped from electrode surfaces and were measured with UV-visible spectroscopy. These results will aid in the development of future bioanalytical devices when a good understanding of the interaction between protein and material surface is needed.


Faculty Mentor: Professor Amanda Harper-Leatherman

Patterns of Foraging Behavior in Atta Leafcutter AntsUndergraduate: Maria Levano ’16, Nicolette Tiernan ’16 (Presenting at Sigma Xi)Abstract: Ant foraging is a collective process that involves the coordinated activity of many individuals. Leafcutter ants forage for enormous amounts of foliage, which they carry back to their nest in order to cultivate their underground fungus gardens. However, leafcutter ants are selective in what type of leaf or plant they will harvest.

We studied the effects of leaf size, leaf shape, distance, and chemical treatment on Atta foraging behavior to determine if they exhibited a resource preference at two different nests. Nest one was based on a relatively flat terrain while nest two was situated on a dirt hill alongside a trail in the União Biological Reserve in Brazil.

Based on analysis of our data, we conclude that selectivity is based on relative familiarity. Data suggests that this could be due to the fact that the treated food sources inhibit pheromone activity in the ant population.



6 7

Nostalgia and Times of Transition: Nostalgia and Perceptions of Success and Life MeaningUndergraduate: Stephanie Lewia ’16Abstract: The study explores the influence of nostalgia on one’s conception of identity and sense of life meaning during transitional times, specifically college graduation. The subjects for the project were second-semester seniors, who are facing a major life transition. Based on previous research, nostalgia should increase one’s conception of identity and sense of life meaning, as well as increase autobiographical memory specificity. It is thought that looking back at the past helps one cope with crises in the present. Participants were either primed to highlight this transitional time, or not. Then, they listened to either nostalgia evoking music, or control music. Subsequently, participants responded to measures of sense of identity and life meaning as well as memory accessibility to see how the presence of nostalgia affects these variables.

Psychology Independent ResearchFaculty Mentor: Professor Linda Henkel

Reducing Your Suffering or Increasing Your Joy?: Negative Empathy Predicts Helping Others to Avoid Negative Emotions Whereas Positive Empathy Predicts Helping Others to Approach Positive EmotionsUndergraduate: Eliza Lewis ’16 (Presenting at Sigma Xi)Abstract: I explored the relationship between positive and negative empathy and approach and avoidance motivations. Because individuals high in positive empathy are particularly sensitive to others’ positive emotions, they should be especially motivated to help others to approach such positive emotions. In contrast, because individuals high in negative empathy are sensitive to others’ negative emotions, they should be motivated to help others to avoid suffering. In Study 1, I found that positive and negative empathy were related to dispositional levels of approach and avoidance motivations and to approach- and avoidance-related personality traits. In Study 2, I presented subjects with a helping appeal framed either in terms of helping to alleviate another’s suffering or helping to increase another’s joy. Here, negative empathy predicted helping only when help was framed as a way to avoid suffering, whereas positive empathy predicted helping only when help was framed as a way to approach joy.

Scholarship: LawrencePsychology Independent Research

Faculty Mentor: Professor Michael Andreychik

Optical Detection of CancerUndergraduate: Run Li ’16, Kevin Vasquez ’16 (Presenting at Sigma Xi and morning session)Abstract: Cancer diagnosis is critical in patient care yet it currently mainly depends on subjective evaluations by a pathologist. Objective alternative cancer diagnosis methods are urgently needed to enhance the accuracy of cancer diagnosis. Our project is one part of “Optical Pathology” research to develop novel approaches of cancer detection with light. The goal of this project is to discriminate cancerous activities from non-cancerous activities from quantitative microscopic study of lung cancer slides. We are focusing on determination of the molecular and structural properties of individual cell of lung tissue and seeking the difference in cancerous and normal tissue. We are using fluorescence microscopy for gathering molecular concentrations, and differential interference phase microscopy for acquiring structural properties. We will also investigate and characterize differences in adenosine triphosphate (ATP) concentration in normal and cancerous lung tissue to develop an objective lung cancer diagnosis method.

Scholarship: Lawrence Physics Independent Research

Faculty Mentor: Professor Min Xu

The Future of Digital Humanities and the Application of the Space-Time Directory in Historic Immigrant Neighborhoods of New York CityUndergraduate: Hannah Livezey ’16Abstract: Over the course of the past two semesters we have compiled data from the New York Public Archives, primarily from the Emigrant Savings Bank, and from ancestry.com to gain an in-depth understanding of the lives of the primarily Irish immigrants that flooded the city in the mid to late 19th century. We are working on a concept for an application that will build upon the initial efforts of the space-time directory team at the New York Public Library and will give users the ability to travel back in time based on their location. At the push of a button people could potentially pull up the names of the people that lived in these homes hundreds of years ago or the lease agreement for a factory that was demolished before their grandparents were born.

Sociology Special Topics: New York Public Library Space/Time DirectoryFaculty Mentor: Professor Kurt Schlichting

Dietary Energy Density is Associated with Gestational Diabetes Status in U.S. WomenUndergraduate: Victoria Lofaro ’16 (Presenting at Sigma Xi)Abstract: The objective of this study was to determine the relationship between Gestational Diabetes (GD), and dietary energy density (ED) in a nationally representative sample of pregnant women residing in the U.S. who participated in the 2009-2012 National Health and Nutrition Examination Surveys (NHANES). Diet quality was assessed using HEI component scores, with FNDDS food codes. Data regarding gestational diabetes (GD) status was provided by the NHANES. Women were categorized as having a positive diagnosis for GD, having a diagnosis of “borderline GD,” or having no gestational diabetes. All data were analyzed using appropriate survey weights and procedures in SAS 9.3. Our results indicate dietary ED, calculated using food only, is positively associated with gestational diabetes. Women without gestational diabetes have a significantly lower dietary ED than those with gestational diabetes or those with borderline gestational diabetes.

Scholarship: LawrenceHealth Studies Capstone

Faculty Mentor: Professor Jacqueline Vernarelli

Snowy Owl Observation at Connecticut’s Beardsley ZooUndergraduate: Laura London ’16, Kenzie McCormick ’16 (Presenting at Sigma Xi)Abstract: The species we studied, that the Species Survival Plan program has also been watching, is the snowy owl (Bubo scandiacus). Although of little concern in Europe, snowy owls are of great concern in the U.S. due to their low rate of reproduction. This lab aimed to determine if snowy owls at the Beardsley Zoo are likely to reproduce by manipulating the owl enclosure by moving familiar perching grounds (a tree and a wooden box) closer together to encourage the owls to be physically closer. In addition, owl mating calls were played aloud outside of the enclosure and camera traps were set up inside the enclosure to monitor the owls on a weekly basis. The info obtained from this study will ultimately help guide the zookeepers’ decisions as to whether or not a new owl should be obtained and switched out with one of the zoo’s owls to encourage mating.

Scholarship: LawrenceVertebrate Zoology Lab


Acquaintance Rape: How It Is Perceived by College StudentsUndergraduate: Demetra Marathas ’16Abstract: The purpose of this study is to better understand what college students define as date rape and its relation to consent. Using a qualitative research design, I will be identifying common themes, such as the existence of drugs and/or alcohol and how long the victim and perpetrator have known each other, in determining what college students typically consider to be definable as “rape.” I will also assess if participants’ non-traditional or traditional attitudes effect their definition of rape.

Scholarship: HardimanPsychology Independent Research

Faculty Mentor: Professor Margaret McClure

Investigating the Function of Stabilimenta in Orb WebsUndergraduate: Alexandra Martin ’17, Kerri McPhail ’16 (Presenting at Sigma Xi)Abstract: For over two decades, scientists have puzzled over the presence of unique structures in the webs of some orb-weaving spiders called stabilimenta. Several hypotheses for the function of stabilimenta have been tested, including a prey-attraction hypothesis. The prey-attraction hypothesis states that these stabilimenta are employed by orb weavers as decorations to lure prey into their webs. To investigate whether stabilimenta served as a visual cue to attract prey, we created a series of webs drawn on fly paper. Over a period of nine days in January, 2016, we placed these artificial stabilimenta around several sites in the Atlantic Rainforest in Brazil. After 24 hours, these were collected and the number of insects caught was counted. Here, we report whether our data support the hypothesis that the stabilimenta function as a prey attractant.



Antifreeze Peptide Disrupts Biofilm Formation in Streptococcus MutansUndergraduate: Jenna Massaro ’16 (Presenting at Sigma Xi)Abstract: Biofilms are communities of cells, surrounded by an exopolymeric matrix, that form on surfaces in the body or environment. Biofilms formed by bacteria such as Streptococcus mutans play a key role in the formation of dental cavities. Disrupting biofilm formation by S. mutans could help prevent dental plaque buildup on teeth. Here we show that a synthetic peptide, Antifreeze P1, can inhibit biofilm formation by S. mutans and other oral streptococci. It is also effective against biofilms of other Gram-positive bacteria. Using an in vitro tooth model of saliva-coated hydroxyapatite discs, we observed a dramatic reduction in attached biofilm biomass of S. mutans when incubated with Antifreeze P1. We used fluorescent microscopy and scanning electron microscopy to further visualize structural changes in Antifreeze P1-treated biofilms. This peptide has potential to be used as an anti-infective agent against dental pathogens or other biofilm-forming bacteria.

Scholarship: Mindlin and Lawrence Biology Independent Research

Faculty Mentor: Professor Juliana Ansari

8 9

BIOLOG Microbial ID System: An Alternative Approach to Identify Unknown MicrobesUndergraduate: Jenna Massaro ’16 (Presenting at Sigma Xi)Abstract: The BIOLOG system is a relatively new alternative approach to microbial identification. In comparison to other current methods of identification, the BIOLOG system is both rapid and extensive as it makes use of a thorough phenotypic test panel. Here we followed the BIOLOG protocol to identify bacteria and yeast from food products, the environment, and the human body. We obtained three bacterial identifications from diverse sources: fermented sausage, human tooth, and the surface of a leaf. This approach has great potential in identifying less commonly known microbes, including yeasts, once the culture conditions are optimized. The BIOLOG system has promising applications not only as a tool for discovery-based labs in undergraduate biology education, but also in identifying and characterizing microbes from a wide array of sources.

Scholarship: Mindlin Foundation and Lawrence FoundationBiology Independent Research

Faculty Mentor: Professor Juliana Ansari

It’s Not How Much You Spend, It’s Where You Spend It: How Consumer Behavior Predicts Dietary Energy DensityUndergraduate: Amanda Massedge ’16 (Presenting at Sigma Xi)Abstract: The objective of this study was to evaluate the relationship between consumer behavior and dietary energy density (ED) in a nationally representative sample of U.S. adults. A diet high in energy density is an established risk factor for obesity. Consumer behavior was evaluated by examining total dollars spent on food each in one of three categories: grocery stores, fast food/takeout and restaurant dining. The data indicates that low-ED diets do not cost more than high-ED diets. These results have implications for public health messaging regarding the cost of healthy eating. Our findings indicate that diets low in energy density can be obtained regardless of money spent at grocery stores, and that increased spending on take-away or fast foods predicts higher dietary ED. Strategies to educate consumers regarding low-cost “healthy” food options may be a successful method of slowing the obesity epidemic.

Scholarship: LawrenceBiology Independent Research

Faculty Mentor: Professor Jacqueline Vernarelli Mobile Application for Match Optimization for Soccer RefereesUndergraduate: Philip Mayer ’16, Drew Mignosa ’16, Kevin Willson ’16 (Presenting at Sigma Xi)Abstract: Even at the highest professional levels of soccer, referees still record relevant game data manually and must later input it into electronic systems for league standings, statistics, and eligibility. These recordings are prone to human error, and there may be discrepancies between individual referee recordings resulting from an inability to communicate easily and effectively. We designed and implemented a cross-platform mobile application that automates the recording and collection of game data on penalties, goals, and more. In our system, referees – using either Android or iOS devices – connect to a central server acting as a point of entry and communication facilitator between each mobile device. Based on the client-server architecture, our implementation features secure authentication, intuitive and simple information entry, and efficient data sharing. The system has the potential to change the way soccer is both administered and spectated, and may also be extended to other competitive games.


Faculty Mentor: Professor Amalia Rusu

A Creation of My HeartUndergraduate: Kerri Moffatt ’16Abstract: A presentation of my musical compositions as part of the musical I am composing for my capstone. I will also detail my musical influences, how the music connects to the story I am writing, the origins of said story and my composing process.

Scholarship: BellarmineMusic Senior Capstone Project

Faculty Mentor: Professor Laura Nash Comparison of Alcohol Content and Volatile Compounds: Humulone and Cohumulone in Home Brewed Beer Versus Industry Brewed Beer, Stone IPAUndergraduate: George Naclerio ’16, Elizabeth Pacer ’16, Chelsey Sidaras ’16 (Presenting at Sigma Xi)Abstract: In our comparison of industry brewed Stone IPA to home brewed beer, we effectively utilized redox titrations to analyze alcohol contents and HPLC (high-performance liquid chromatography) to study volatile compound content. The results of these titrations demonstrated that the Stone IPA (alcohol content: 6.9%) experimentally contained 5.66% alcohol, which we will then compare to the experimental alcohol content calculated for the home brewed beer (alcohol content: 5.5%). In regards to the flavoring components found within beer, we expect that the Stone IPA should have higher amounts of volatile compounds (both humulone and cohumulone) as compared to the home brewed beer because of the higher alcohol content. For this reason, the Stone IPA should also taste more bitter than the home brewed beer, a conclusion that will be made qualitatively. Our results are relevant to the industrial and social use of IPA beer.

Scholarship: LawrenceChemical Instrumentation Lab


‘N Synch: The Evolution of Jaw Muscle Activation in the BatoidsUndergraduate: David Neubauer ’16 (Presenting at Sigma Xi)Abstract: Batoids (skates and rays) have specialized jaws that can function independently due to their cartilaginous skeleton, euhyostylic jaw suspension, and the presence of a highly flexible symphysis at the center of the upper and lower jaws. Sharks and skates have demonstrated unilateral activation when feeding on complex prey items. We investigated pairwise activation of the jaw muscles in four species of batoids (Dasyatis sabina, Gymnura micrura, Potamotrygon motoro, Urobatis halleri) from four families in order to examine the evolution of synchronous and asynchronous feeding behaviors. We hypothesized that these rays would use synchronous activation when feeding on small prey and unilateral activation to process larger prey items. Two asynchrony indices were used to quantify the duration of muscle activation and the lag, or degree by which muscles are activated out of phase.

Scholarship: LawrenceBiology Independent Research

Faculty Mentor: Professor Shannon Gerry

Characterizing the pH Responsiveness of Dithiolane-Modified Peptide Self-Assembly Structures Undergraduate: Ruben Neves ’17 (Presenting at Sigma Xi)Abstract: Recently, there has been great effort to develop a set of “bottom-up” design strategies that direct the assembly of peptides into specific supramolecular structures. The factors that control and stabilize peptide self-assembled structures, including side chain electrostatic interactions, sterics, and hydrophobicity, are non-covalent, and therefore reversible. One strategy to expand and diversify the intermolecular stabilizing interactions of peptide self-assembly involves the integration of dynamic covalent disulfide chemistry. Herein, we report the synthesis of lipioc acid-modified peptides and the characterization of the dynamic disulfide network on the supramolecular structures. The responsiveness of the supramolecular peptide surface disulfide-exchange polymerization to pH changes was investigated spectroscopically. The combination of dynamic covalent disulfide chemistry and peptide self-assembly will expand the current chemical diversity of biomaterials to yield environmentally responsive supramolecular assemblies with reactive surfaces.


Faculty Mentor: Professor Jillian Smith-Carpenter

Fostering Emancipation Undergraduate: Carina Nieto ’16Abstract: Fostering Emancipation is a short documentary that follows 20-year-old Imani Bayne, a student at Hostos Community College, as she prepares to exit the foster care system in September. The film will take a closer look at the emotional and psychological impact of remaining in the foster care past the age of 18 as well as the impending exit date.

Scholarship: Lawrence Film Senior Capstone Seminar

Faculty Mentor: Professor Patrick Brooks

Zinc and Copper Analysis of Ribbed Mussel (Geukensia demissa) Pallial Cavity FluidUndergraduate: Elizabeth Pacer ’16 (Presenting at Sigma Xi)Abstract: My research consists of analyzing the zinc and copper concentrations in the pallial cavity fluid of the ribbed mussel (Geukensia demissa). Zinc and copper, two metals with previously demonstrated potential defense properties, were detected in large concentration in Eastern oysters suggesting that these metals contributed to the Eastern oysters’ antibacterial behavior. To determine whether a different, but related organism displays similar behavior with similar causes, I study the zinc and copper concentration of the pallial cavity fluid of mussels from the same area in Long Island Sound. I will make conclusions about the significance of zinc and copper in the mussel, and about the potential these metals have in organismal defense.


Faculty Mentor: Professor Amanda Harper-Leatherman

Active and Passive Noise Cancellation Applied to an Ordinary Household ApplianceUndergraduate: Tony Phantharangsy ’16, Vincenzo Moretti ’16, Christopher Calitri ’16, Michael LoTurco ’16 (Presenting at Sigma Xi)Abstract: Vacuums are a common household appliance, making noise that people are all too familiar with. The average Shop Vac produces 81 dBa of noise from 10 feet, which can be quite the nuisance. The majority of the noise comes from air turbulence within the vacuum as well as changes in flow velocity. To combat the noise, passive and active noise cancellation techniques will be implemented. A redesigned, smooth air flow path will cut down on turbulence and insulation will help cut down on vibration. An adaptive filter will take in the noise that the vacuum makes, create an anti-noise, and emit it through a speaker to cancel some noise. With these techniques, the vacuum is expected to be 17-20 dBa quieter.


Faculty Mentor: Professor Jeffrey Denenberg

10 11

They “Kick A** and Take Names”: LGBTQ Identity Politics and Young Adult Speculative FictionUndergraduate: Abigayel Phillips ’17Abstract: My Literature Capstone project explores how the subject areas of Young Adult literature, LGBTQ identity representation and the genre of Speculative Fiction intersect to address the importance of Young Adult literature in the development and exploration of identity politics for adolescent readers. I focus both on the social aspects of representation and identity as well as the textual phenomena of a new wave of Speculative Fiction that offer viable and dynamic representations of LGBTQ characters and plots. Ultimately, my project can offer some solutions for how to increase the circulation and publication of more diverse texts with LGBTQ representation as well as promote the importance of both Young Adult literature and Speculative Fiction.

Literature Concentration CapstoneFaculty Mentor: Professor Nels Pearson

Lactic Acid Bacteria Isolation from Fermented FoodsUndergraduate: Samantha Porter ’16Abstract: The purpose of the experiment was to assess the potential for fermented food products containing lactic acid bacteria to serve as a preventative measure against water borne pathogens like Vibrio cholera. It was hypothesized that fermented Chaas and raw Cheese would contain bacteriocin producing lactic acid bacteria that would inhibit the growth of Vibrio strains and E.coli.

Water Research SeminarFaculty Mentor: Professor Jo Yarrington

“On the Threshold she Paused”: Doors in Wharton’s The Mother’s Recompense and The Decoration of HousesUndergraduate: Angela Sammarone ’16Abstract: Doors, which Edith Wharton devotes an entire chapter to in The Decoration of Houses, are the primary focus of this project. I will consider their simultaneous symbolism in The Mother’s Recompense as both a necessary staple of interior design and as a safeguard for a woman’s nature. Beginning with Wharton’s background in interior design, Section One will assess the influence and reception of The Decoration of Houses. Section Two will then shift more broadly to Wharton’s relationship with interior design and how elements of architecture permeated her fiction to express introspective qualities of her characters and external observations of society. Finally, Section Three will analyze the doors present in The Mother’s Recompense as instruments of exclusion and admittance to examine how the physical door space – the threshold – mirrors the omnipresent conflict women face, debating whether or not to make themselves visible to others.

Scholarship: Hardiman Humanities Institute Seminar

Faculty Mentor: Professor Emily Orlando

The Disturbance on Atlantic Rainforest BioacousticsUndergraduate: Monica Sciacca ’16, Frank Segreto ’16 (Presenting at Sigma Xi)Abstract: The Atlantic Rainforest of Brazil is considered one of the world’s biological diversity hotspots. Although more than 90% of the original forest has been cleared, the remaining forest fragments are home to thousands of species that cannot be found anywhere else on earth. Our goal was to assess the degree in which forest fragmentation has influenced species diversity. Bioacoustic recordings were taken at two separate locations, one located one mile into the União Biological Reserve, and one at the edge of the reserve. Two ten-minute recordings were taken every three and a half hours from 6:30 a.m. until 7:30 p.m. All recordings were analyzed using RavenLight Pro and Avisoft and the results compared throughout the day and from site to site. Results show similar trends in species activity throughout the day, however, spectrogram analysis reveals a higher degree of bioacoustic complexity of the undisturbed habitat. This indicates that bioacoustics may be an effective way to assess species diversity in the future.



Find Me in the Jungle Undergraduate: Riley Smith ’17 (Presenting at Sigma Xi)Abstract: Howler monkeys (Alouatta caraya), golden lion tamarin (Leontopithecus rosalia), and capuchin (Cebus capucinus) are all species of New World monkey found in Brazil’s Atlantic rainforest. Due to urban and agricultural development, less than 8% of the original rainforest remains, fragmented in a small number of protected reserves. Over a two-week period during January 2016, a survey was conducted in the União Biological reserve in order to confirm the continued presence and relative location of howlers, golden lion tamarins, and capuchins. Surveys began at 5 a.m. every morning over four different reserve trails. The presence of monkeys was confirmed through vocalizations or by direct observations. Data recorded was then plotted on a satellite image of the reserve. Following data patterns, three species appear to be centralized at the middle area of the reserve, rather than the edges suggesting fragmentation is greatly reducing the land suited for habitation resulting in considerable range overlap.

Scholarship: Lawrence Brazil Zoology Field Experiences


Humanitarian Relief Services Undergraduate: Anmol Tabassum ’16Abstract: Field Training Exercise ATLANTIC HOPE is held at the Public Safety Training Complex of Indian River State College (IRSC) in Fort Pierce, Florida in March. This four-day exercise tests the ability of disaster relief and humanitarian studies participants to apply what they have learned about the planning and conduct of relief missions in a full-scale simulated disaster environment.

Humanitarian Independent ResearchFaculty Mentor: Professor Julie Mughal

Egan School of Nursing and Health Studies Projects

Know Your NumbersUndergraduate: Cynthia Allinson ’16Abstract: Poster presentation of visualizing data collected after educating patients on their important health numbers.

Transition Seminar for Professional Nursing Practice for RNsFaculty Mentor: Professor Carole Pomarico

Medication Management and Adherence in the ElderlyUndergraduate: Maria Ardila ’16Abstract: Medication adherence and management has always been a concern in the elderly population. As a professional group, nurses can develop an education plan in order to help this population adhere to their medication regimen. Literature suggests that 20-70% of medications are not taken as prescribed. Non-compliance with medication is a major public health problem that is affecting our community. Educating our population would increase medication adherence, which is vital in preventing, managing and curing illnesses and, hence, is linked with positive health outcomes. My research consists in understanding the impact of medication non-compliance in the elderly and how we, as healthcare workers, can help with this problem.


HOUDINI: Eliminating Unneeded CathetersUndergraduate: Elizabeth Avery ’16Abstract: This project examines eliminating urinary catheters that are not necessary to patients by highlighting the benefits of reassessing what the expectations of the nurses are. Giving the nurses a reassessment tool (HOUDINI) to help them determine if the patient still needs the catheter or not will help direct them in a quick and simple way. The acronym gives a different reason as to why the foley should not be removed yet for each letter. This allows clear criteria for the nurses to assess, and only d/c the foley when appropriate. My goal is to help nurses see the importance of removing unneeded foley catheters and how easy it is to do a quick reassessment daily.

Transition to Professional Nursing Faculty Mentor: Professor Kathleen Lovanio

What to Expect After the UnexpectedUndergraduate: Emily Baldwin ’16Abstract: After a patient experiences sexual assault and comes to the hospital, a trained nursing professional will complete a sexual assault kit. A sexual assault nurse/forensic examiner (SANE) will complete a step-by-step kit on a patient that can take up to a couple of hours. The kit can be very embarrassing and may cross personal boundaries for a patient, but is essential in collecting DNA evidence. In order for a patient to feel comfortable, they should be made aware of the process and have educational material provided to them as they wait for the SANE nurse.

Transition to Professional NursingFaculty Mentor: Professor Katherine Saracino

Nursing Checklist for Patients Who SmokeUndergraduate: Elizabeth Ball ’16Abstract: The VA floor, 4West, needs a checklist that the nurses can use upon admitting a patient. This checklist will be directed specifically towards patients who are reliant on nicotine. Not only will this pamphlet have the “checklist” but it will also have alternatives that the VA offer like, nicotine patch, e-cigarette, and resources such as incentive spirometers that help with the deep breathing sensation that cigarettes have.

Transition to Professional NursingFaculty Mentor: Professor Kathleen Lovanio

12 13

Cardiac Catheterization Undergraduate: Kathleen Bednarz ’16Abstract: Cardiac catheterizations are a common invasive procedure performed to visualize a person’s blood supply to the heart. This project is focused on patient education about what cardiac catheterization is and what to expect. This includes before, during, and after the procedure to help reduce any stress the patient may have and overall improve his/her experience in the hospital.

Scholarship: LoyolaTransition to Professional Nursing

Faculty Mentor: Professor Sheila Iacono

Does Bedside Report Positively Impacts HCAHPS Scores When it Comes to Patient SatisfactionUndergraduate: Mariana Bermeo ’16Abstract: Bedside reporting provides nurses with an opportunity to improve patient safety and increase patient collaboration in plan of care. Patients are now given opportunity to be more active in their own care with bedside reporting. Because of bedside report, patients’ overall satisfaction had greatly improved and is supported by HCAHPS results. To prove the effectiveness of bedside report, this project compares patient satisfaction surveys results pre-bedside report with the new ones, after bedside report was implemented. This approach is unique because it analyzes two different sets of results as opposed to concentrating solely on the present benefits of bedside reporting.


Sleep Deprivation in the ICUUndergraduate: Alicia Brizzolara ’16Abstract: This project will involve research on the impact of sleep deprivation in ICU patients. This research then will be incorporated into a presentation for night shift ICU nursing staff on measures to promote sleep for better health outcomes for their patients.


Medication Teach-BackUndergraduate: Shannon Buckley ’16Abstract: This project focuses on teaching nurses about the importance of completing medication teach-back with every patient. Medication teach-back is a process that ensures the patient fully understands what medications they are taking to prevent readmission into the hospital.

Transition to Professional NursingFaculty Mentor: Professor Sheila Iacono

Family Education on Advance DirectivesUndergraduate: Shelby Butwell ’16Abstract: This presentation is focused on teaching families about advance directives and the importance of encouraging a loved one to take the time to get one in case of a future emergency.

Transition to Professional NursingFaculty Mentor: Professor Sally Gerard

Cardiac Nurse Education Post PCI Care Undergraduate: John Cassone ’16Abstract: This project examines nurse education for cardiac units to assess existing knowledge of post PCI care to reduce bleeding complications at the approach site. Surveys done before and after education sessions present evidence-based practice to prevent bleeding complication to gauge knowledge gained. New standards of practice are to be implemented on unit with quick reference guide for evidence-based care instructions for nurses.


Increasing Nursing Knowledge: Post PCI Bleeding ComplicationsUndergraduate: John Cassone ’16Abstract: Will an education program for CVU nurses addressing post PCI (Percutaneous Coronary Intervention) care increase knowledge of bleeding complications? An educational in-service using evidence-based literature is provided to cardiac unit. Pre and post education surveys are conducted to assess learning.


Sequential Compression DevicesUndergraduate: Matthew Castellano ’16Abstract: To research the benefits for utilizing sequential compression devices during the post-operative period.

Transition to Professional NursingFaculty Mentors: Professors Katherine Saracino, Michele LeCardo

Hello from the Bedside: A Literature Review on Bedside Shift ReportUndergraduate: Makenzie Cisewski ’16Abstract: This research is a literature review of the evidence to transition to bedside shift reporting in hospital settings. The poster will discuss the benefits to this type of nursing report and provide an example on how to conduct a bedside shift report.

Transition to Professional NursingFaculty Mentor: Professor Linda Roney

Pressure Ulcer Prevention in ICUUndergraduate: Anna Columbro ’16Abstract: This project examines pressure ulcer occurrences in intensive care units and what puts patients at risk for ulcers specifically on those units. It will educate RNs and unit staff on the importance of turning patients frequently enough to prevent ulcers given all the factors that put them at risk.


New Protocol for NICU Moms: Use of Breast Pump Within Six Hours of Birth to Promote LactogenesisUndergraduate: Julia Croteau ’16Abstract: This project aims to inform clients of the importance of stimulation in promoting the process lactogenesis, or breast milk filling. When a mother delivers a baby whom enters the Newborn Intensive Care Unit (NICU), the mother’s breasts are not stimulated by their suckling baby. Informing mothers who want to breastfeed, to pump within six hours, due to the physiology of lactogenesis, via a pamphlet handout, will be essential to improving patient satisfaction at Greenwich Hospital.

Transition to Professional Nursing Faculty Mentor: Professor Katherine Saracino

Improving Patient Satisfaction: Effective Communication ModelUndergraduate: Rene Crowe ’16Abstract: This project created a three-step communication model to improve patient satisfaction throughout care. The tool will implement procedures to improve communication between the nurse and the patient to create an effective environment while maintaining a level of service. Through effective communication, the nurse will be able to assess the needs of the patient and utilize the responses in order to provide premier service.

Transition Seminar for Professional Nursing Practice for RNsFaculty Mentor: Professor Ann Kardos

Alternative Approach to Incontinence Undergraduate: Anna Cruz ’16Abstract: Urinary incontinence, if left unmanaged, can have a substantial negative effect on a person’s health and overall daily life. This project investigates the complications that present themselves with incontinent patients and suggests implementing the need for a change from disposable adult diapers to Capri bladder control pads. The use of Capri bladder control pads can enable the individual to maintain dignity as well as prevent leakage. These incontinence pads will also help minimize the risk of skin damage and breakdown. This project will look into some of the problems and risks associated with the use of specific incontinence products.


Stroke Management EducationUndergraduate: Gina Curro ’16Abstract: This project focuses on educating patients about managing an altered lifestyle after having a stroke.


Will a Formalized Education Program Increase Compliance Among a Selected Group of Church-Going African Americans, Age 30 - 60? Undergraduate: Donna Delva ’16Abstract: This research paper explores why African American age 30 - 60 are noncompliant to HTN meds and the myth surrounding noncompliance. This paper will research whether the myths are believable or not, if people who use alternative medicine are satisfied with the results of their alternative medicine, or if they would have preferred using prescribed medication. This topic is particularly important because with noncompliance of HTN medication this could lead to more chronic disease such as DM, CVD (Cardiovascular Disease). The source of material for this research will be journal, magazines, websites, questionnaires and web-based articles from the Fairfield School library.


Under Pressure: Knowing the Appropriate Bed Surfaces for Your PatientsUndergraduate: Ashley DePaul ’16Abstract: My project focuses on the different bed support surfaces available in the hospital setting and evaluating which would be the best choice for a patient, depending on skin integrity and/or presence of preexisting pressure ulcer(s).

Scholarship: Bellarmine SocietyTransition to Professional Nursing

Faculty Mentor: Professor Sally Gerard

14 15

Move To ImproveUndergraduate: Katherine DeStefano ’16Abstract: This is a project, teamed up with St. Vincent’s, to work on mobility and ambulation of patients. I am creating a brochure for the hospital to use to educate patients and families on why mobility is a vital part of the patient’s health and steps they can take to make sure the patient is moving enough each day.

Scholarship: BellarmineTransition to Professional Nursing

Faculty Mentor: Professor Danielle Hall

A Patient’s Guide to Understanding Cardiac MedicationsUndergraduate: Carly Donnis ’16Abstract: The purpose of the project is to assist patients and their families with understanding the most commonly used cardiac medications on the Main 4 South Telemetry Unit at the Stamford Hospital. The project includes a pamphlet-teaching tool that will be implemented in the patient’s stay while at the hospital and provided for them to take home during discharge.


The Use of Teach Back Method in the Pediatric Post Anesthesia Care UnitUndergraduate: Katherine Dostal ’16Abstract: My project focuses on the importance of teach back method in the pediatric post anesthesia care unit. The project will be focused on teaching and refreshing the nursing staff about the importance of teach back method for both patients and families.

Transition to Professional NursingFaculty Mentor: Professor Kathleen Visinski

Keeping Patients Safe, One Step At A Time Undergraduate: Danielle Esposito ’16Abstract: I have created a poster for safe patient handling. Using the Banner’s Mobility Assessment Tool (BMAT), nurses will be able to quickly assess a patient’s mobility status. This will allow nurses to easily identify the equipment needed for safe patient mobilization. This tool will categorize the patient from a Level 1 to 4 based on their ambulation abilities and equipment needs. The nurse driven tool will allow for immediate patient ambulation and ensures staff safety.

Transition to Professional NursingFaculty Mentor: Professor Michele Lecardo

Teaching Staff Nurses the CAM AssessmentUndergraduate: Rebecca Fallon ’16Abstract: There was an educational need identified for the staff nurses on 7N at St. Vincent’s Medical Center. These nurses were not using or documenting the CAM assessment, which is a tool that helps to detect delirium in patients. The goal of this project was to teach staff nurses when and how to use the CAM assessment tool appropriately.

Transition to Professional NursingFaculty Mentor: Professor Danielle Hall

Fight Thrush: Medicate and BrushUndergraduate: Casey Flynn ’16Abstract: Oral thrush is a medical condition that causes white lesions on the tongue or inner cheeks. Although it can affect anyone, it is most often seen in individuals with suppressed immune systems. On 9 South, an oncology unit at St. Vincent’s Medical Center, oral thrush presents itself in the mouths of many cancer patients. Education about prevention measures and medications used to treat thrush is lacking. Through the use of a pamphlet, the goal is to educate patients at risk for developing thrush on ways to prevent thrush and types of medications used to treat it.


Disruptive BehaviorUndergraduate: Linda Foster ’16, Sandra Howard ’16, Althea Johnson ’16Abstract: This project examines disruptive behavior, and the effects and intervention that can be employed to reduce it.


Controlling Your DiabetesUndergraduate: Melissa Ganley ’16Abstract: I am making an educational brochure for patients about diabetes and the importance of controlling it.

Transition to Professional NursingFaculty Mentor: Professor Anka Roberto

Abusive Head Trauma - An Educational Intervention Graduate: Suzanne Gleichauf ’17, Krystyna Isbell ’17, Jody Kusheba ’17Abstract: This project was completed using evidence-based research in a systematic approach. Abusive head trauma is a nationwide crisis and this presentation addresses a significant practice problem, which is relevant for nursing intervention. Future research should be aimed at nurses providing a multi-modal, in-hospital teaching program to new parents after childbirth as studies have shown it prevents abusive head trauma. In this poster, we will present the background, problem, literature summary, significance, and proposed future project that will help drive practice change.

Research Methods for Evidence-Based PracticeFaculty Mentor: Professor Carole Shea

Why the Wellness Program at an Insurance Company is Not Successful in Preventing Health Problems of Sedentary Lifestyle at WorkUndergraduate: Ana Granda-Flores ’16Abstract: My project will cover the major problems caused by prolonged sitting and will present ideas for employers to establish more effective workout programs. One of my main focuses will be to explore the reason why employees are not enrolling in the already existing wellness programs. Employers as well as employees will benefit from this project, which can be seen as both a money saver and a lifestyle change to foster a healthier population.


Prevention and Infection Control in Hemodialysis PatientsUndergraduate: Ying Guiza ’16Abstract: This project focuses on evaluation modalities and educational programs that are essential for healthcare providers in the ongoing prevention for sepsis in hemodialysis clinics. Sepsis is one of the biggest issues that healthcare facilities face in all settings. Sepsis is seen in most settings from hospitals, long-term facilities, acute centers, same-day surgical centers and many others. Long-term facilities like dialysis centers are most at risk.


Infant Sleep SafetyUndergraduate: Laura Hart ’16Abstract: This Capstone’s goal is to educate parents of infants on the importance of “back to sleep” and crib safety.


Removal of Indwelling Urinary Catheter: Proper ProtocolUndergraduate: Erin Hastings ’16Abstract: This project is focused on gathering research-based evidence to support the best protocol for the removal of indwelling urinary catheters.


Faculty Mentor: Professor Katherine Saracino

Medication Education for Parents of Critically Ill Children Undergraduate: Casey Heely ’16Abstract: A research project illustrating the importance of medication education for critically ill children and a fill in the blank pamphlet to facilitate that process.

Scholarship: MagisTransition to Professional Nursing

Faculty Mentor: Professor Kathleen Visinski

Skin-to-Skin Care in the Operating Room: How to Implement This Care and the Benefits of Doing SoUndergraduate: Alyson Jacobs ’16Abstract: Skin to skin between a mother and their newborn directly after a Cesarean Section in the OR has many benefits. I will be educating staff on how to implement this care and the benefits of doing so.

Transition to Professional Nursing Faculty Mentor: Professor Cynthia Bautista

Taking Control of Type II Diabetes Undergraduate: Nicole Kaps ’16Abstract: This project studies the significance of proper control of patients’ Type II Diabetes and the effect it has on their overall health. My target audience is the patients with the goal to educate them. Short term effects of uncontrolled blood sugar can be dangerous such as hyper/hypo glycemia, which can lead to dizziness and falls in the hospital, but long term uncontrolled blood sugar can lead to chronic problems with the heart, kidneys, and eyes. It is crucial to teach patients the importance of self-maintenance both in and out of the hospital to prevent kidney or heart failure and more.

Scholarship: Bellarmine Transition to Professional Nursing

Faculty Mentor: Professor Linda Roney

16 17

Improvement in Patient and Family Communications in the Peri Op Area to Improve Patient overall SatisfactionUndergraduate: Cynthia Kazzi ’16, Maribeth Oleynick ’16Abstract: The Periop area at Bridgeport Hospital recently started the Press Ganey Survey program, which is a standard patient satisfaction survey. The results showed our area needed to improve its communication and visitation guidelines in the immediate post operative phase. We instituted simple measures to improve these areas and the results have been remarkable. Simple hourly rounding in the Family Waiting area, early visitation in the PACU by family members and an overall friendly and welcoming atmosphere was implemented. The project cost zero dollars and the results are priceless.

Transition Seminar for Professional Nursing Practice for RNs Faculty Mentor: Professor Carole Pomarico

Pain Assessment and Management in the Pediatric PACUUndergraduate: Jenna Kelley ’16Abstract: Pain management is a top priority in the pediatric post-anesthesia care unit (PACU). Assessment of pain post-operatively is needed to determine the pain intervention and management necessary to prevent any post-op complications. Pediatric parents are often unaware of how pain is managed and what to expect for their child in the postoperative setting. Pain affects nearly 100% of patients in the PACU and requires appropriate management by the healthcare team and education of family members, yet it is still understudied.


Violence in the Workplace Undergraduate: Madeline Kerins ’16Abstract: For this project I am going to analyze violence in the workplace. Because there are an abundance of detox patients on the floor where I work, I have noticed an increased amount of incidence regarding violent behavior between patients and staff. As these patients are detoxing, they become very irritable and act out towards the people that are trying to help them. I also aim to assess, observe, and document the interactions between staff members on this floor. There is a completely different dynamic on this floor than those that I have witnessed in past hospital settings.


“Reading the Feeding” Oral Feeding Readiness in Preterm InfantsUndergraduate: Lindsay Klemm ’16Abstract: In the United States, 1 out of every 10 births is preterm. Oral feeding is a significant milestone for all preterm infants. Preterm infants typically don’t have the suck, swallow and breathe coordination that full-term infants have. Due to this, gavage feedings are used. Transition from gavage feedings to oral feeding should be based on several different factors and the infant should be monitored closely during all oral feedings for any signs of respiratory distress.


The Healing Touch — A Guide to Self Care for the Oncology NurseUndergraduate: Emily Kopas ’16Abstract: This project identifies common anxieties and stressors among Oncology Nurses. Emotional exhaustion and compassion fatigue is addressed by evidence-based resources and support services developed for Oncology Nurses. These support services and coping strategies provide the nurses with effective ways to cope and medicate stress.


Nix the Noise- Alarm FatigueUndergraduate: Michelle Laspino ’16Abstract: An evidence based research project addressing the safety hazard of alarm desensitization and alarm fatigue impacting patient safety and care. This project also addresses the lack of education nurses have about customizing the alarm settings based on the patient to reduce the amount of false alarms.


Fall Risk Amongst Stroke PatientsUndergraduate: Delaney Lucas ’16Abstract: This project will present the education that is needed for a patient’s status post stroke. Many patients do not realize that after a stroke they are extremely weak and why that may be. This project will present the education needed for these patients explaining what their limitations may be and why. This will be provided to patients in the form of a brochure.


Sepsis Education in the ICU is Important to Improve Core Measure EducationUndergraduate: Christin Lucia ’16, Helen Tracey ’16Abstract: With the education of the ICU nurses we are hoping to improve the early goal directed therapy bundle elements to meet CMS guidelines.


Prothrombin Complex Concentrate: Nursing Facts to Improve Patient Care Undergraduate: Danielle Lug ’16Abstract: My project will focus on educating the Emergency Department nursing staff at St. Vincent’s Medical Center about Prothrombin Complex Concentrate, a combination of clotting factors and proteins that stops bleeding in patients who have suffered a traumatic injury. The project specifies the nature of the concentrate, therapeutic levels, how to get the concentrate from the pharmacy and the process of giving it to patients. Information will also be provided that details patients who may not be suitable to receive the concentrate.


Prevention of Post Operative FallsUndergraduate: Jacqueline McAvoy ’16Abstract: This research project focuses on creating a post operative educational tool to help prevent falls from occurring while patients are recovering from anesthesia/post op delirium.


Can Antibiotic-Impregnated Catheters Reduce the Risk of Infection Associated with EVD’s?Undergraduate: Erin McCarthy ’16Abstract: External ventricular drainage systems are placed in Neuro intensive care units every day, but unfortunately infections do still occur. However I am researching how using antibiotic impregnated catheters or silver impregnated catheters can help reduce the risk of infection.


Complementary and Alternative Therapies Available at Yale New Haven HospitalUndergraduate: Laura McKee ’16Abstract: My approved Capstone Project is to create an informational brochure that would be included in the informational folder each patient receives when arriving on the sickle cell unit, oncology unit, or possibly to all Yale New Haven Hospital care units. The packet would educate patients about stress and stress reduction, complementary therapies available to patients at Yale, brief descriptions of the therapies offered, and the demands/requirements of those therapy options. Many therapies are listed as only available to oncology patients. Since the unit I work on is a sickle cell unit which cares for overflow oncology patients, this capstone project will be beneficial to oncology patients and all patients who qualify for the alternative therapies on my unit and throughout the Yale New Haven Hospital system.

Transition to Professional Nursing Faculty Mentor: Professor Sheila Iacono

Hourly RoundingUndergraduate: Rachel Morton ’16Abstract: This project identifies the importance of hourly rounding for patient safety as well as satisfaction.


Childhood Nutritional Education in the Prevention and Reduced Incidence of Childhood ObesityGraduate: Dorothy Mulroy ’16Abstract: My project is a data analysis of the importance of educating children about proper nutrition. With educational outreach the incidence of childhood obesity in the literature is impacted positively. Nutrition education is a tool to use for the prevention of childhood obesity.


Alarm Fatigue: Individualizing Alarms in the ICUUndergraduate: Deirdre Munday ’16Abstract: Reduce the amount of false and unnecessary alarms in the ICU by educating and reminding the staff to initiate alarm management at the beginning and throughout each shift. The purpose is to decrease alarm fatigue and ensure that each medical alarm signal is a proper alert and responded to promptly.


18 19

Central Line Infection PreventionUndergraduate: Kathryn Nash ’16Abstract: This project examines preventing the number of central line infections in an ICU setting with specific protocols for medical staff to follow when accessing their patients’ central line.


Faculty Mentor: Professor Kathleen Lovanio

Under PressureUndergraduate: Brianna Nunes ’16Abstract: For my senior capstone I will be completing a research project on an identified learning need for the surgical intensive care unit at the VA Hospital. The topic I have chosen to focus on is device related pressure ulcers. Patients in ICUs are placed at higher risk for these ulcers due to the many devices that are being used to keep them medically stable. These devices can cause skin breakdown and can create different staged pressure ulcers. I will present my findings to the VA Hospital staff and the Fairfield nursing community to incorporate into their practices.

Scholarship: HardimanTransition to Professional Nursing

Faculty Mentor: Professor Kathleen Lovanio

The Importance of Early Swallow EvaluationsUndergraduate: Kelly O’Brien ’16Abstract: This project will focus on early nursing intervention related to swallow evaluations and preventing further hospital acquired issues for those patients who have suffered from a cerbrovascular accident.


What Specific Concerns do Nurses Have When Using the Suicide Assessment Tool at Silver Hill Hospital?Undergraduate: Sophia Peart ’16Abstract: Suicide is the 10th leading cause of death in the United States, and is the second leading sentinel event in hospitals. In 2013, it was stated that 41,149 deaths were as a result of suicide. Suicide costs society over $44.6 billion a year in combined medical and work loss costs. Nurses practice on the front line in healthcare and have the greatest opportunity to identify and intervene with suicidal patients.


Checking Orthostatics Should Be Automatic: Catch All Before They FallUndergraduate: Danielle Pittala ’16Abstract: This project focuses on orthostatic hypotension in relation to falls. Research was collected to support the statement that orthostatic hypotension can increase the incidence of falls. Through research, a plan was proposed to increase the frequency of monitoring orthostatic hypotension, and in turn decreasing incidence of falls, for more patient-centered care.


Sitters in the Hospital Setting Undergraduate: Nicole Prodan ’16Abstract: My project is an in-depth look at the practice of sitters, i.e., healthcare workers who closely monitor patients in the abscence of nurses in the hospital setting. My hope is to provide all members of a healthcare team with a greater understanding of sitters’ effectiveness, and when they should be implemented to ensure the safety of the staff and the patient.

Scholarship: MagisTransition to Professional Nursing

Faculty Mentor: Professor Michele Lecardo

Zika Virus Undergraduate: Marisa Randazzo ’16Abstract: This project focuses on the Zika Virus and its teratogenic effects on pregnant women. In addition, a pamphlet-teaching tool will be provided for this population.

Transition to Professional NursingFaculty Mentor: Professor Alyssa Guard

Bedside Rounding Undergraduate: Holly Ream ’16Abstract: Bedside rounding is currently being implemented in hospitals all over the country. This is a topic that nurse managers want to put into action. I researched the advantages of bedside rounding at St. Vincent’s Medical Center for both the staff and patients.


Zika Virus and Pregnancy Undergraduate: Kelsey Reardon ’16Abstract: I created a poster presentation to be used as a learning tool for the staff of Yale New Haven’s Primary Care Center. This poster provides important information on the Zika Virus, as well as identifies a flow sheet that staff should follow when reporting possible Zika Virus in patients. Information on the poster also includes fetal complications of the virus as well as some key preventative measures.


Minimizing Your Discomfort with Complementary Therapies at Stamford HospitalUndergraduate: Mary Kate Reilly ’16Abstract: I will be describing the different types of non-pharmacological interventions that can be used for pain relief. I will describe the Planetree Philosophy of Care used at Stamford Hospital and what they offer patients for non-pharmacological pain relief and services. It will be assembled in a turning laminated set of cards on a ring that can be distributed to patients for better utilization of their resources.


A Veteran-Centric Poverty Simulation: A Transcendental Phenomenological Research StudyGraduate: Anka Roberto ’16Abstract: Using a convenience sample, a qualitative transcendental phenomenological research design was utilized after implementing a six-hour poverty simulation with local VA staff and second degree nursing students at a Jesuit institution. Participants immersed themselves in roles of families living in poverty and completed post simulation qualitative surveys. Results: Eight themes noted in the qualitative analysis were those of empathy, advocacy, an awareness of poverty, an awareness of resources, changed perspective of the poor, a need for less judgment of poor, systems perspective on poverty, and the need for better communication among agencies. The participants verbalized that they benefitted from the experience and thought that all healthcare workers and social service workers should undergo such an immersive training session.

DNP SeminarFaculty Mentor: Professor Kathleen Wheeler

Common Medications of the ICUUndergraduate: Nicole Russell ’16Abstract: This project focuses on the most commonly used medications in the standard hospital intensive care unit. This project will include professional medical terminology, as well as common lay terms to help the non-medical person, such as family members, understand the information being offered. Throughout the course of this project, the Greenwich Hospital Pharmacy has been and is contacted to gain the most accurate information about medications used in the Greenwich Hospital Intensive Care Unit. The purpose of this project is to provide educational information to patients, family members, and other visitors.

Transition to Professional NursingFaculty Mentor: Professor Cynthia Bautista

What To Know When You Go NPOUndergraduate: Joellyn Schappler ’16Abstract: My research was focused on NPO diets and preoperative fasting. This project discusses the suggested guidelines for the duration of preoperative fasting. It also discusses the reality of how long patients typically fast prior to a procedure regardless of the guidelines set out by the American Heart Association of Anesthesiology. This project explains the benefits preoperative fasting but also the negative impacts it can have on the body. The project discusses some barriers to keeping to specific NPO timing guidelines due to the uncertainty of the operating room schedules in a hospital.


Living with COPDUndergraduate: Kathleen Sirna ’16Abstract: I am creating a brochure for patients and their families educating them about living with COPD.


Couplet Care Undergraduate: Ewa Skiedziel ’16Abstract: Couplet care is a project that will improve the quality of care on postpartum unit when implemented. It is the first stage to make informed decisions, involve staff and to create and promote teamwork to move forward with carrying out the couplet care project in the facility.


20 21

Medication InterruptionUndergraduate: Thalia Soriano ’16Abstract: In nursing, nurses are constantly getting interrupted when they’re medicating patients. As a result, medication interruptions lead to medication error. It is important to educate nurses, healthcare professionals and family members to decrease the risk of medication errors. By decreasing medication errors, nurses will have better outcomes and improve patient safety.


Breastfeeding in Labor and DeliveryUndergraduate: Angelica Staib ’16Abstract: I will be researching and creating a pamphlet for the Stamford Hospital Labor and Delivery unit that focuses on the things mothers should know about breastfeeding in those first hours of life in Labor and Delivery. The goal of the unit is to decrease unnecessary formula supplementation.


Promoting Equitable Nurse- Patient AssignmentsUndergraduate: Felicia Staropoli ’16Abstract: My project identifies the problem of nurse-burnout due to lack of CNAs on the floor and uneven patient assignments. Research studies show the effectiveness of implementing an acuity scale to create a fairer nurse-patient assignment. The acuity scale measures the patient based on the amount of care and education they require, as well as the amount of meds they take. This project evaluates the effectiveness of implementing the scale.

Transition to Professional Nursing Faculty Mentor: Professor Kathleen Lovanio

Supplemental Nutrition in the Medical ICUUndergraduate: Rachel Steriti ’16Abstract: This project will address an identified need of the Medical Intensive Care Unit at Yale New Haven Hospital’s St. Raphael’s Campus, specifically the need for education regarding supplemental nutrition administration and documentation. It was recently discovered that the MICU has a mere 18 percent rate of nutrition supplement documentation, as compared to the hospital-wide high of 41 percent in the transplant unit. It is inconclusive whether the low documentation rate is a product of a low administration rate of supplemental nutrition or simply the failure to properly document the administration of supplemental nutrition, or some combination of the two. This project will strive to address this unit-specific issue and to increase the rate of nutrition supplement documentation among nurses through two primary objectives: first it will educate on the importance of nutrition supplementation in the critical care patient to improve outcomes, and second it will reinforce the importance of accurate documentation in nursing care.


The Benefits of Direct Bedding Undergraduate: Kelly Traft ’16Abstract: A look in an Emergency Department on the benefits of direct bedding used during triage. This includes moving the patient directly from the waiting room into a patient room. This process yields higher patient satisfaction scores and also allows the patient to be seen by a doctor faster.


Neutropenia and Tips to Prevent InfectionUndergraduate: Hang Tran ’16Abstract: This project discusses the solutions to protect neutropenic patients from infectious diseases. Neutropenia is a decrease in the number of white blood cells. These cells are the body’s main defense against infection. Neutropenia is common after receiving drug treatments and increases the risk for infection. Therefore, this project is an evidence base practice research that demonstrates the problems of being neutropenic, and implements necessary changes on the Oncology floor at Bridgeport Hospital.


Shhhh!Undergraduate: Hayley Wilson ’16Abstract: This project focuses on educating nurses and staff on the negative effects of unnecessary noise on patient outcomes in the inpatient setting.


Post Operative Bowel Care/Management Undergraduate: Rebecca Zappala ’16Abstract: I am researching the best evidence-based practice for nurses to better manage patients’ postoperative bowel care.

Transition to Professional Nursing Faculty Mentor: Professor Anka Roberto

Sigma Xi

Electronic Medical RecordsUndergraduate: Daley Baldwin ’16, Matthew Engel ’16Abstract: Our study investigates the use of electronic medical records and electronic health records. We were interested in understanding how electronic health records impact the quality of care in a provider- patient relationship. We also wanted to investigate new technologies for patients in recording and tracking their own personal health and fitness.

Health Studies CapstoneFaculty Mentor: Professor Michael Pagano

Beer, Bourbon, and Beakers: Phenolic Flavor Compounds found in Alcoholic BeveragesUndergraduate: Nicholas Bernier ’16, Robert Gargano ’17, Hadley Orr ’16,Kevin N. Vasquez ’16, Abstract: We will present a comparative inquiry regarding brown ale and bourbon. We will compare the presence and relative quantities of phenolic flavoring compounds contained in brown ale and bourbon. The group decided that it was a topic of interest because phenolic compounds contribute to different tasting notes that people enjoy. The instrumental chemical analysis techniques used to analyze brown ale and bourbon were Gas Chromatography- Coupled Mass Spectrometry (GC-MS) and High Pressure-Liquid Chromatography (HP-LC).

Instrumental Analytical Chemistry LabFaculty Mentor: Professor Matthew Kubasik

Understanding Stories Through Artificial IntelligenceUndergraduate: Evangelos Boliakis ’16, Duy Creel ’16, William McDonnell ’17Abstract: An A.I. (artificial intelligence) is used for understanding information, which allows a machine to efficiently gather data and eventually act upon that data. We will create an A.I. program for understanding stories by incorporating text recognition and information acquired from a script applier mechanism, along with a conceptual analysis of natural language. The script applier mechanism program allows us to effectively apply created situational scripts in grammatical sentences for the user to comprehend, and the conceptual analysis of natural language details the construction of concepts through keywords and phrases. Our goal is to finish our basic program with the ability for a user to input a text, and the A.I. to output answers asked by the user via a graphical user interface. Although basic, this program will be the building block for future reading applications.

Engineering Senior DesignFaculty Mentor: Professor Jamie Macbeth

Synthesis and Characterization of Cobalt(II) Model Complexes for Liver Alcohol DehydrogenaseUndergraduate: Sheila Bonitatibus ’17 Abstract: The Miecznikowski Laboratory investigates the preparation and reactivity of functional models of natural metalloenzymes, specifically liver alcohol dehydrogenase. The Miecznikowski laboratory has already synthesized and characterized a family of pincer ligand precursors with nitrogen and sulfur donor atoms, and has metallated the ligand precursors to form zinc(II) complexes, which are models for liver alcohol dehydrogenase. We are now interested in preparing cobalt(II) model complexes of liver alcohol dehydrogenase. The products will then be analyzed through multiple techniques including X-ray crystallography, NMR spectroscopy, ultra-violet visible spectroscopy, infrared spectroscopy, electron paramagnetic resonance spectroscopy, electrospray mass spectrometry, electrochemistry, and we will use density functional theory calculations to further understand our characterization results. The goal of the study is to answer the question of how well thiones model thiolates in biomimetic chemistry. The synthesis and characterization of the ligand precursors and cobalt(II) complexes will be presented.

Chemistry Independent ResearchFaculty Mentor: Professor John Miecznikowski

Identification of Putative Transcription Factors and the Evolution of the Peroxiredoxin Gene FamilyUndergraduate: Bryan Bystrianyk ’16Abstract: The Peroxiredoxin (PRDX) gene family controls the production of antioxidant enzymes, which regulate peroxide levels and mediate signal transduction in cells. Peroxiredoxins are also important for their role as tumor suppressors, and overexpression of certain members of this family has been noted in certain human cancers. The peroxiredoxin family consists of six genes: PRDX1 – PRDX6. Much research has been focused on the proteins themselves and the DNA sequences for these genes but the evolution of these genes and how they are regulated has been less researched. In this study, we used bioinformatics tools to identify transcription-binding sites and putative transcription factors for each member of the PRDX family. We also generated a maximum likelihood phylogenetic tree in order to better understand this gene family, which can aid in future cancer research.

Biology Independent ResearchFaculty Mentor: Professor Ashley Byun

22 23

Alpha-Lactalbumin Purification and Characterization Undergraduate: Lucas Cabral ’16Abstract: Bovine a-Lactalbumin is the primary protein component of milk and is an essential nutrient. As part of the routine biochemistry 1 lab course, this protein is isolated from purified samples of whey from non-fat milk. The crucial step of isolation is performed via affinity chromatography where the unique copper component binds to the agarose column while the majority of other proteins elute through. While this is the most specific method of isolation, it’s less cost effective than other methods. Instead, this experiment will be conducted in the same manor, but the proteins will be isolated using sephadex G-50 chromatography which separates proteins on the basis of size. While this method is known to be less specific, it is much more viable in terms of cost.

Biology Independent ResearchFaculty Mentor: Professor Lenka Biardi

An Examination of the Relationship Between Entitlement, Gender and Sexual Consent BehaviorsUndergraduate: Brigid Callahan ’16Abstract: The present study investigates if undergraduate students’ gender and sense of relationship entitlement are associated with specific types of behaviors they perceive utilizing to convey sexual consent, as well as to the behaviors they expect their intimate partners to use to convey sexual consent. A quasi-experimental design is employed. The IV’s are gender and participant score on a self-report measure of relational entitlement (restricted, assertive, or inflated). The DV’s are participant’s scores on self-report measures of the utilization (and expectation of others to utilize) different sexual consent behaviors (nonverbal signals of interest, passive behaviors, initiator behaviors, verbal cues, and removal behaviors). Data collection for this study is ongoing. Findings from this research could potentially expand existing knowledge of how college students conceptualize and engage in sexual consent, and create more informed interventions for sexual assault prevention and education regarding sexual consent.

Psychology Independent ResearchFaculty Mentor: Professor Margaret McClure

Direct-to-Professional Pharmaceutical Advertising and its Effect on Health Care in the United StatesUndergraduate: Nicole Capra ’16Abstract: The pharmaceutical industry is one of the most profitable sectors and biggest spenders on marketing in the United States with approximately 10 cents of every U.S. health care dollar spent on pharmaceutical drugs (Fischer, 2014). Advertising directly to health care professionals (DTP) accounts for the bulk of pharmaceutical marketing expenditures and includes detailing, sample giveaways, medical journal advertisements, and informational events. This study analyzes five DTP advertisements for marketing strategies used to optimize pharmaceutical companies’ ability to educate and promote new drugs to health care professionals. Through a review of current literature, this study also discusses the impact that DTP pharmaceutical advertising has on physician-prescribing behavior and the ethical debate of whether persuasive marketing activities create a conflict of interest on the part of the physician.

Health Studies CapstoneFaculty Mentors: Professors Michael Pagano, Brian Walker

Fish Suck: Comparing Feeding Kinematics and Suction Pressure in BluegillsUndergraduate: Caroline Rzucidlo ’18, Rachel Carlowicz ’18 (Presenting at Sigma Xi)Abstract: Bluegills diverge into two ecomorphs based on habitat. Littoral bluegills primarily feed on invertebrate larvae found in the benthos and pelagic bluegills feed on Daphnia in the water column. This study compared feeding kinematics and suction pressure of the ecomorphs when feeding on brine shrimp, mealworms and earthworms. We hypothesized that pelagic bluegills would generate more suction to feed on brine shrimp while littoral bluegills would generate greater suction to feed on mealworms and earthworms. We found no significant difference in pressure between ecomorphs when feeding on mealworms and earthworms. However, littoral bluegills swam a greater distance to capture both prey types. When feeding on brine shrimp, pelagic bluegills began suction farther from the prey item and reached peak pressure faster. There were significant differences between the two ecomorphs, however they do not support the hypothesis that pelagic bluegills generate more suction when feeding on earthworms and mealworms.

Scholarship: HardimanBiology Independent Research

Faculty Mentor: Professor Shannon Gerry

Effects of Cholesterol Depletion on Leukemia Cell ViabilityUndergraduate: Michelle Cawley ’16, Damini Patel ’16Abstract: Cancerous cells exhibit accelerated growth and proliferation compared to normal cells. Research has shown that limiting cholesterol availability can slow cancer cell growth. We explored the relationship between cell viability and cholesterol levels in K562 cells, a chronic myelogenous leukemia cell line. K562 cells were treated with methyl-b-cyclodextrin (MbCD), an agent that depletes cellular cholesterol from lipid raft regions of plasma membranes. Our results showed that methyl-b-cyclodextrin reduced K562 leukemia cell viability in a dose- and time-dependent manner in short-term assays (<6hr). Since K562 cells are early progenitors of erythrocytes, monocytes and granulocytes, we then examined whether MbCD-mediated changes in cholesterol levels impact erythrocyte differentiation. However, MbCD treatment at low concentrations (<2mM) and long term (24hr +) treatments did not appear to impact K562 cell viability or differentiation towards erythrocytes. Together, this study suggests that cholesterol metabolism may differentially affect leukemia cell viability and pathways of differentiation.

Special Topics in BiologyFaculty Mentor: Professor Catherine Andersen

Exploring the Relationship Between Lipoprotein Metabolism and Leukemia Cell SurvivalUndergraduate: Layra Cintron-Rivera ’18, Adam Doerr ’16, Lydia Dupree ’18Abstract: Cholesterol is a ubiquitous biological compound that is essential to cellular function. In addition to providing structural support and integrity to cell membranes, cholesterol and its metabolites also serve as regulatory signaling molecules that impact gene expression. Cellular cholesterol levels can be modulated through interactions with lipoproteins, including low-density lipoproteins (LDL) and high-density lipoproteins (HDL). Research suggests that lipoproteins may impact cancer cell growth and survival due to their ability to mediate cholesterol flux into and/or out of the cell, thereby altering the availability of cellular cholesterol required for rapid cellular proliferation and membrane synthesis. Given the potential role of lipoprotein metabolism in cancer cell survival, this project investigates whether LDL and HDL can impact the viability and gene expression of human chronic myelogenous leukemia (CML) K562 cells. This study will further elucidate the clinical significance of cholesterol and lipoprotein metabolism in human health and disease.

Biology Independent ResearchFaculty Mentor: Professor Catherine Andersen

Comparing Levels of Theobromine and Caffeine in Milk, Dark and White Chocolate Using HPLC AnalysisUndergraduate: John Domenico ’16, Alexander LaCroce ’16, Juliana Widak ’16Abstract: In a world where chocolate is digested every day, consumers need to be aware of the qualitative and quantitative assessments of alkaloids entering their bodies. Our group plans to analyze three types of Godiva® chocolate (dark, milk, and white), screening each sample for caffeine and theobromine. We aim to present the quantity of caffeine and theobromine in each sample using High Performance Liquid Chromatography. We will compare our HPLC data to literature data. Our milk and dark chocolate labels include percent cacao, with which we will compare our calculation of percent cacao using experimentally determined amounts of theobromine and caffeine. Additionally, caffeine and theobromine are only present in cacao, which is not present in white chocolate, therefore we do not expect to see any caffeine or theobromine in white chocolate.

Chemistry Instrumentation LabFaculty Mentor: Professor Matthew Kubasik

Direct-to-Consumer Pharmaceutical Advertising and Its Impact on Health CareUndergraduate: Lauren Falkanger ’16Abstract: The market for direct-to-consumer pharmaceutical advertising has immensely grown in recent years. While there are some restrictions and regulations in place for what pharmaceutical companies can advertise, the market is driven by capitalist demand and the industry of DTCA is viewed merely as a business now. This project will use scholarly reviews to further look at the impact that direct-to-consumer advertising has on the attitudes of consumers, emotional and endorser appeals, perceptions of consumers, and lastly, the costly implications. In today’s market, pharmaceutical companies are seen using a variety of methods and tactics to entice consumers to ask providers for prescription medications. This project will also analyze five DTC ads as a means to understand the methods and tactics that are used in various advertisements. The results will provide further analyses of ways in which pharmaceutical companies are successful in their advertising methods to consumers.

Health Studies CapstoneFaculty Mentors: Professors Michael Pagano, Brian Walker

“Keep Calm and Don’t Drink the Water”: Shedding Light on Fairfield University’s WatershedsUndergraduate: Ryan Fritz ’17, K’ron Simmons ’18Abstract: Since January of 2015, the environmental science lab research assistants have been part of an ongoing effort to monitor campus environmental quality. Field data used to evaluate and make recommendations to improve the campus watershed was collected and processed from nine on campus bodies of water throughout the duration of the school year and summer. The YSI model 85 probe was used to take the initial chemical readings of the water bodies. Water samples were collected for further chemical analysis in the lab. The data was entered into a database and statistically analyzed to determine if there is a correlation between seasonal changes, natural and unnatural events with non-point source fertilizer run-off. The data shows what Fairfield University is draining into the Long Island Sound and what changes the University needs to implement to reduce environmentally detrimental runoff.

Biology Independent ResearchFaculty Mentor: Professor James Biardi

Drone Research at the Beardsley ZooUndergraduate: Alex Fulco ’16, Jennifer Schwartz ’18, Abstract: Animal enrichment, or the process of creating an engaging environment, is used to encourage natural behavior and increase breeding among animals in captivity. This lab investigated the affect of drones on certain animals at the Beardsley Zoo, observed the reactions of the animals to the drones, and investigated drones as animal enrichment tools. Additionally, drones were used to gain footage of animal enclosures from the respective animal’s point of view. Animals investigated include wolves, bison, turtles, sea otters and large cats. The drones used were the Ollie Robot, the Parrot A.R. Drone, and a GoPro camera. Throughout the lab, animal interaction with the drones was observed and recorded. Additionally, the Parrot A.R. Drone’s built in camera captured the surrounding enclosures from the respective animal’s point of view, by being flown at the animal’s eye level. The findings in this lab will encourage further research with drones and animal enrichment opportunities.

Vertebrate Zoology LabFaculty Mentor: Professor Ashley Byun

24 25

Fairfield University Health PortalUndergraduate: Alexander Fulco ’16, Ryan Saunders ’16Abstract: The goal of this project is to create a health and wellness-based website for the entire Fairfield University community. Working with the National Consortium for Building a Healthier Academic Communities, we aim to create a completely integrated website that students, faculty, and staff can use as a tool for their health and wellness. Currently on campus there is no integrated system that has all the health resources available in one place. This website would tie together all areas of health and wellness on campus including physical, mental, financial, spiritual, and nutritional.

Health Studies CapstoneFaculty Mentor: Professor Brian Walker

The Effects of Acute Intranasal Oxytocin on Anxiety and Social Behaviors Undergraduate: Kristina Gallagher ’16Abstract: In humans, exposure to valproic acid (VPA) during development is associated with an increased risk for Autism Spectrum Disorder (ASD). One potential treatment is oxytocin (OXT), a neuropeptide involved in social behaviors. This study was conducted to examine whether acute OXT would restore social behaviors in VPA-exposed females. Pregnant rats were injected with 600mg/kg of VPA or saline. After weaning, pups were assigned to three test groups: VPA-exposed treated with OXT(n=5) or saline(n=5) and saline-exposed treated with saline(n=6). Administration of the treatment was done before behavioral testing for anxiety (elevated plus maze) and social behaviors (sociability test). We found differences between VPA-sal and other groups on elevated plus maze. On the sociability test, VPA-sal rats spent less time with the novel rat than controls (p<.07) suggesting they were less social, and OXT appeared to restore the behavior. A new test for prosocial behaviors is being piloted and will be explained.

Psychology Supervised ResearchFaculty Mentor: Professor Shannon Harding

Cognition Impairments in Personality Disorders: Working Memory in Schizotypal PD, Avoidant PD, and Healthy ControlsUndergraduate: Maddi Gervasio ’16Abstract: Schizotypal personality disorder (SPD) individuals have impaired cognitive functioning similar to schizophrenia patients, but the extent of this similarity is not fully known. This study focuses on the working memory of SPD individuals, compared to Avoidant Personality Disorder (AvPD) individuals and Healthy Controls (HC). The hypothesis is that SPD participants will have greater impaired working memory, lower PASAT scores and higher DOT test scores than AvPD participants, and SPD and AvPD will have greater impairment than the HC; as well as impairments found in SPD participants will be consistent with impairments in schizophrenia. SPD participants had significantly greater impairments than AvPD participants, t(96)= 2.44, p < .001, and HC t(109) = 3.97, p < .001. AvPD participants had significantly greater impairments than HC, t(101) = 1.29, p = .021. Therefore, the impairments are due to the fact that SPD is on the schizophrenia spectrum.

Psychology Supervised ResearchFaculty Mentor: Professor Margaret McClure

Feeding Strategies at the Beardsley ZooUndergraduate: Meghan Grzybowski ’16, Mary Smyth ’18 Abstract: Mixed species exhibits in zoos are an exceptional way to provided a dynamic and interactive environment for animals. However, mixed species exhibits result in challenges as the different animals can interfere with the well being of others through harassment and food stealing. We explored different feeding strategies of callimico monkeys (Callimico Goeldii ), a Red-Rumped Agouti, (Dasyprocta leporina) and a three-toed sloth (Bradypus), all residents of a single mixed exhibit at the Connecticut Beardsley Zoo. Issues of food stealing by the callimico monkeys from both the agouti and sloth required that some changes be made to feeding practices in this exhibit. After observing the behaviors of all three animals, we were able to devise simple new feeding methods, which successfully eliminated food stealing by the callimico monkeys.


Examining High Levels of Positive and Negative Empathy as Risk Factors for Different Clinical Disorders Undergraduate: Teah Hayward ’16Abstract: Existing work has distinguished empathizing with others’ positive and negative emotions as two separate processes, both with positive implications for relationships and prosocial behaviors. But, this work also suggests that there may be negative consequences of extremely high levels of negative or positive empathy. This study demonstrates the clinical implications of having high levels of either positive or negative empathy by finding that high levels of negative empathy are positively correlated with a greater risk for depression, while high levels of positive empathy are positively correlated with a greater tendency to take risks, which is related to multiple clinical disorders. Contrary to the hypothesis, high levels of positive empathy were not found to be correlated with a risk for mania. Together, these results provide evidence that positive and negative empathy may contribute to risk factors for clinical disorders, including depression, alcohol use disorder, and gambling addiction.

Psychology Independent ResearchFaculty Mentor: Professor Michael Andreychik

Differential Thread AdjustersUndergraduate: Brian Herman ’16, Kevin D. McCaffrey ’16, Brett Mikolajczyk ’16, Chris Rutigliano ’16Abstract: Sensitive opto-mechanical mounting applications, such as those used in photolithography applications, require extreme stability in order to provide the high resolution details demanded in the nanometer range. These mounts must be stable in position when exposed to stress induced by loading, temperature variation, and vibration. Preventing drift over time is of particular interest to prevent frequent and often costly recalibration of these mounts. In addition to these mounts being stable, they also must have the appropriate adjustment sensitivity to be able to precisely set the mounts in their particular application. The main objective of this project is to study the stability and adjustment sensitivity of commercially-available-off-the-shelf ( COTS ) Differential Thread Adjusters ( DTA’s ) versus custom designed adjustment methods such as Fine Pitch Adjusters and DTA’s, while evaluating their commercial feasibility.

Engineering Senior DesignFaculty Mentor: Professor Andrew Judge

Disparities in Access to Nutritional Food in Food Pantries and their Impacts on Diet-Related Health OutcomesUndergraduate: Jaime Hinkel ’16Abstract: Chronic Illnesses such as cardiovascular disease and diabetes are heavily influenced by the nutritional quality of an individual’s dietary intake. Individuals who are most susceptible to these illnesses are food insecure individuals who, because of insufficient economic resources, are unable to have reliable access to safe and healthy foods. Many of these individuals must rely on emergency food resources such as food pantries to provide for themselves and their families. The nutritional quality of the foods that are found in these pantries is of vital importance to the overall health and well being of food insecure populations. The purpose of the current study is to evaluate the nutritional quality of foods found in pantries in Bridgeport, CT to see if the quality of these foods is reflected in the health outcomes data (i.e. blood pressure, BMI, and blood glucose) of individuals who frequent these pantries.


Automated Alignment of a Laser Welded Medical DeviceUndergraduate: Yaroslav Kohut ’16, Steven Shiner ’16, Christian Vrankovic ’16, Austin Wesolowski ’16Abstract: Our team has been tasked by Northeast Laser and Electropolish to automate the process of straightening medical devices used in endoscopic knee surgery. These devices are created by laser welding a tube to a cap; however the weld periodically creates a fractional bend outside of the vendor requirement, which is 0.002 inches of total radial deviation. By applying a perpendicular force to the cap of the device as it’s rotating, the cap will bend back into within the vendor’s tolerance. Our final design includes a Dunham Lathe that holds a 5C collet within its spindle, an armature with two tangential roller ball bearings that is connected to a series of X and Y-directional linear actuators, an M-Drive step motor that will rotate the device, and a pressurized air system that will lock the device into place. Our design targets to align more than three medical devices per minute in production.

Engineering Senior DesignFaculty Mentor: Professor Michael Zabinski

Phenotype Analysis of a-Actinin-2 Heterozygous and Knock Out Mice Undergraduate: Firdaus Kudia ’17Abstract: During a summer internship at Boston Children’s Hospital, the rare genetic disorder, congenital myopathies, was studied. During the internship, we wanted to study the function of alpha-actinin-2 in cardiac and skeletal muscles, therefore, we developed a mice model with a knockout of alpha-actinin-2. Since alpha-actinin-2 is responsible for slow twitched muscles, we further examined the phenotype of the knockout mice and exacerbate their phenotype under stress conditions.

Summer InternshipFaculty Mentor: Professor Shelley Phelan

Scientific Method, Scientific Facts and Spiritual OrientationUndergraduate: Alisia LoSardo ’16, Justin Paton ’17Abstract: Modern-day society runs on science, however the extent to which individuals truly understand its fundamental principles and practices is open to question. The results of previous studies indicate that individuals – both laymen and academic intellectuals – tend to know far less about science than they think. This is especially true of the science of psychology, in which the subject matter is, or at least includes the behavior of the scientists themselves. The current study sought to identify links between one’s professed knowledge of The Scientific Method, their actual knowledge of scientific facts and concepts and their expressed degree of spirituality. Participants – composed of both students and faculty – completed a survey consisting of a biographical component and several-information gathering components aimed at determining the true extent of scientific understanding and commitment. The ultimate aim of our study is to determine why scientific findings are so often ignored or disregarded by modern society.

Psychology Independent ResearchFaculty Mentor: Professor Ronald Salafia

26 27

Effect of Temperature and Oxygen Variability on Two Fish Species in a Connecticut LakeUndergraduate: Coleman Macuch ’17Abstract: All organisms have specific habitat requirements necessary for survival. We studied variability in habitat conditions for fish in Lake Lillinonah in Western Connecticut. We chose northern pike and largemouth bass because they have different habitat preferences and are important for recreational fishing. We used literature values for physiological requirements and temperature and oxygen data collected by automated sensors, to determine the presence of optimal versus stressful conditions for each species. The results show that Lake Lillinonah experiences hypoxic conditions during the summer months, and stressful water temperatures for pike, but there is considerable variability among years. Current summer water temperatures are within the optimal range for bass, which is a warmer water species. As the climate continues to warm, we expect more frequent stressful conditions for both species.

Biology Independent ResearchFaculty Mentor: Professor Jennifer Klug

Behavioral and Developmental Observations of Myrmecophaga Tridactyla at the Connecticut Beardsley ZooUndergraduate: Alexandra Martin ’17, Samantha Porter ’16 Abstract: The Giant Anteater (Myrmecophaga tridactyla) is an insectivore endemic to Central and South America. Little is known about this species regarding basic behavioral patterns. The purpose of our research was to observe the behavior of two sexually mature Giant Anteaters at the Connecticut Beardsley Zoo. Direct observations were supplemented with multiple motion-activated cameras located within their indoor enclosure. These videos, along with staff reports, were collected and compiled twice a week. On Feb 13, 2016, the female gave birth to one pup. As a result, we began to focus our research on the development of the pup, behavior patterns between the pup and mother, and behavior patterns of the father. Videos taken mere hours before the estimated time of birth revealed dominance and mating behaviors in the male as well as stress, underscoring the importance of separating the male and the female before, during, and after the time of birth.

Vertebrate Zoology Lab Faculty Mentor: Professor Ashley Byun

The Effect of Alternative Therapies on Decreasing Psychosocial Aspects in Women Undergoing IVFUndergraduate: Jenna Massaro ’16Abstract: In vitro fertilization (IVF) can negatively affect psychosocial factors of women undergoing the treatment. The use of alternative therapies to treat stress and anxiety has been applied in conjunction with IVF. This systematic review aims to evaluate the effect of alternative therapies on decreasing psychosocial factors in women undergoing IVF treatment. Papers included in this review were published in the last six years, and study participants were limited to women undergoing IVF as well as some form of alternative intervention. Additionally, the study had to be measuring the effect of the alternative therapy on decreasing psychosocial measures (i.e. anxiety, stress, etc.). Databases CINAHL and PubMed were searched, yielding 12 relevant studies, one of which was qualitative while the rest were quantitative. Overall, results demonstrated that alternative therapies, for the most part, decrease anxiety and stress for women undergoing IVF.

Health Studies CapstoneFaculty Mentor: Professor Jenna LoGiudice

Effects of Intranasal Oxytocin on Anxiety and Social Behaviors in an Animal Model for AutismUndergraduate: Ellen Masters ’16Abstract: Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by social and communicative impairments. Exposure to valproic acid (VPA) during pregnancy produces ASD-like symptoms in offspring, making this a plausible rodent model for the disorder. Because oxytocin (OXT) is a neuropeptide that contributes to social behaviors, we studied whether intranasal administration would improve behavior in VPA-exposed male rats. Pregnant female rats were injected subcutaneously with VPA (600mg/kg) or Saline on gestational day 12.5. Male offspring then received 0.8 IU/kg of OXT or Saline from P21 to P41. Tests for anxiety, sociability, and sociosexual behaviors were conducted, and revealed that VPA rats show heightened anxiety (p<.05) and reduced sociability (p<.05) compared to controls. Additionally, OXT treatment appeared to restore behavior to normal levels. We predict OXT to enhance sociosexual behaviors. These findings have direct implications for the treatment of neurodevelopmental disorders like ASD with OXT.

Scholarship: Magis ScholarPsychology Supervised Research

Faculty Mentor: Professor Shannon Harding

Limiting Distributions for Topological Markov Chains with HolesUndergraduate: Philip Mayer ’16Abstract: How do mathematicians study chaos? How can we begin to study systems intrinsically lacking order? In our poster, covering research completed for the 2015 Fairfield REU in Mathematics and Computational Science, we introduce the methods used by mathematicians to study the evolution of dynamical systems and their statistical properties. We discuss our findings, namely proofs for the existence of limiting distributions, which represent equilibria for different classes of systems, including those from which mass or energy may escape.

REU Mathematical ResearchFaculty Mentor: Professor Mark Demers

Synthesis and Characterization of Ruthenium (II) Carbene ComplexesUndergraduate: Maura Morgan ’16Abstract: The Miecznikowski Laboratory is interested in preparing precatalysts for the reduction of aldehydes and ketones. We are particularly interested in preparing ruthenium(II) precatalysts as complexes containing this metal have been reported in the literature to catalyze the reductions of aldehydes and ketones. We have prepared a ruthenium(II) complex that contains the following ligands: p-cymene, two iodide ions, and 1,3 dimethyl benzimidazole. This complex was prepared by reacting ruthenium(II) para-cymene dichloride, 1,3 dimethyl benzimidazole iodide, potassium acetate, and potassium iodide. We have obtained a single crystal structure of the complex and are currently interested in preparing more of this complex and fully characterizing the complex using NMR spectroscopy. Another goal is to study the decomposition pathway of the complex as the p-cymene ligand may fall off during catalysis and thereby decomposing the catalyst. The syntheses and characterization of the ruthenium(II) complex will be presented.

Chemistry Research and Seminar Faculty Mentor: Professor John Miecznikowski

The Relationship Between Light and Sound Stimulation in Cryptobranchus alleganiensisUndergraduate: Marissa O’Donnell ’18, Hayley Roberts ’17Abstract: The hellbender (Cryptobranchus alleganiensis), a species of giant salamander found in eastern North America, and is currently on the IUCN Red List classified as near threatened. Little is known about hellbenders. This study assessed hellbender activity through tests that analyzed light and sound. This study tracked hellbender activity by observing walking, head movement, change in body orientation, swimming, and hiding under structures in the tank while light and sound were manipulated. Sound between 1,250 and 2,500 hertz were played in periods, which proved to periodically increase hellbender activity. Light was changed in varying degrees of intensity. This alteration of light proved that lower light intensity increased behavior where higher light intensity decreased behavior. The relationship possibly correlates with their nocturnal lifestyle. The connection between presence of sound and periodical increase in activity supports hellbenders sensitivity to vibrations. Information found in this study will hope to provide data for future experiments.


The Impact of Co-Rumination on Negative Affect: An Exploration of Gender DifferencesUndergraduate: McKenna O’Shea ’16Abstract: Previous research has pointed out the significance of co-rumination and its impact on stress and depression levels, especially in women who are more likely to preform the behavior. One hundred and twenty nine participants were tested on how much co-rumination impacts stress and if the propensity to co-ruminate is greater in females than in males. Participants were given a demographics questionnaire, a Beck Depression Inventory II, and a Co-Rumination Questionnaire. They were then given a stressful or neutral prompt to write about, and then answered a Positive and Negative Affect Schedule. Next they were given another stressful or neutral prompt, and then answered the same questionnaire. Our results showed a significant relationship between co-rumination and negative affect, but not between gender.


Synthesis and Characterization of SNS Pincer Ligand Precursors and Zn (II) ComplexesUndergraduate: Tyler J. Ostrowski ’16Abstract: We have developed and synthesized a series of tridentate pincer ligands possessing two sulfur- and one nitrogen-donor functionalities (SNS), based on bis-imidazole or bis-triazole precursors. The tridentate SNS ligands incorporate thione-substituted imidazole or triazole functionalities. We have prepared somewhat rigid ligand systems through usage of 2,6-dibromopyridine as a ligand precursor. We have also prepared more flexible ligand systems by employing the starting material 2,6-(dibromomethyl) pyridine to introduce a methylene linker into the pincer ligand. We have metallated these ligand precursors to form zinc(II) complexes containing these tridentate ligands. We are interested in preparing ligand precursors based on 1,2,4 triazoles instead of 1,3,4 triazoles, which were previously prepared in the Miecznikowski Laboratory. The goal is to metallate the novel ligand precursors with zinc(II) and copper(II) salts. A detailed description of the syntheses, and characterization (NMR Spectroscopy and ESI-Mass Spectrometry) of the SNS zinc(II) complexes and ligand precursors will be presented.

Chemistry Research and SeminarFaculty Mentor: Professor John Miecznikowski

Lactic Acid Bacteria as a Preventive Agent Against Pathogenic BacteriaUndergraduate: Samantha Porter ’16Abstract: Lactic acid bacteria is naturally occurring in a wide variety of foods including dairy products and fermented foods. These cultures are considered beneficial to the health of the digestive tract due to the production and secretion of bacteriocins. Bacteriocins are protein-based toxins that kill closely related bacteria, some of which may be pathogenic. The purpose of the experiment was to screen for the presence of lactic acid bacteria in raw cheese and chaas (fermented yogurt) and to assess the bacteriocin activity against Vibrio fischeri, Vibrio harveyi, and Escherichia coli. This was achieved by homogenization of food products, isolation of lactic acid bacteria, and overlays inoculated with the bacteria of interest (V.fischeri, V. harveyi, E.coli). Preliminary results revealed that both food products contain bacteria of the Lactobacillus genus. Bacteria isolated from the chaas exhibited inhibition on Escherichia coli. No inhibition was present from lactic acid bacteria on Vibrio strains.

Water Research SeminarFaculty Mentors: Professors Jo Yarrington, Olivia Harriott

28 29

Characterization of Cancerous Lung Tissue via Fluorescent BiomarkersUndergraduate: Daniel Quinn ’16, Dominic Schioppo ’16Abstract: Cancer is a disease that affects millions of people each and every day. This terrible disease has been the focal point of numerous research studies that are designed to gain more useful information and a better understanding of the complexity of cancer. This study is intended to elucidate the properties of cancerous lung cells using the ratios of expression of innate fluorophores and excitation techniques via various wavelengths of light, which can lead to easier identification of cancerous lesions.

Health Studies CapstoneFaculty Mentors: Professors Brian Walker, Min Xu

Protestant Work Ethic and Locus of Control in Determining Predicted Post-Undergraduate Career Success: Private University vs. Community CollegeUndergraduate: Marco Rodis ’16, Ryan Saunders ’16Abstract: This study investigated levels of Protestant Work Ethic and Locus of Control and post-undergraduate career aspirations between private university and community college students. Undergraduates from a private university and a community college in Connecticut were given a survey consisting of career and education oriented questions, the Protestant Ethic scale, and the Internal-External Locus of Control scale. Results suggest that community college students have more of a drive to become successful in spite of factors that would seem to hold them back. Conversely, private university students appear to sincerely believe that they are unable to become upwardly mobile in the world due to their previous generation’s success. These results highlight a serious disparity among college students that had not been present in previous generations. This could have significant implications on the way students may be educated and prepared for their careers.

Psychology Independent ResearchFaculty Mentor: Professor Dorothea Braginsky

Comparison of Efficiency of GMO Detection by PCR Using Lab Made Reagents vs. Commercial KitUndergraduate: Kristen Rothdeutsch ’17Abstract: The efficiency of an Edwards buffer and PCR primers for GMO detection in food products was compared. Reagents made in the Molecular Biology Preparatory lab were compared to those supplied in a commercial kit. DNA was extracted from three sources: non-GMO control plant tissue, a known GMO control plant tissue, and a snack food source that contained GMO corn product using either a lab-made Edwards buffer or kit-supplied Edwards buffer. A PCR comparison of kit-supplied primers versus lab-made primers of the DNA extractions was performed. Primers that detect the 35S gene (indicator of GMO) and tubulin primers (control for DNA extraction) were used in a PCR reaction and samples were then analyzed by agarose gel electrophoresis. Based on preliminary results, there does not appear to be any difference between the Edwards buffer and primers made in the lab and the reagents provided in the commercial kit.

Biology Independent ResearchFaculty Mentor: Professor Lenka Biardi

Syntheses, Characterization, and Oxygen Reactivity of Three Coordinate SNS Copper(I) Pincer ComplexesUndergraduate: Michael Smith ’16Abstract: Recently, we have developed and synthesized a series of tridentate pincer ligands, each possessing two sulfur- and one nitrogen-donor functionalities (SNS), based on bis-imidazole or bis-triazole precursors. The tridentate SNS ligands incorporate thione-substituted imidazole or triazole functionalities. We have prepared somewhat rigid ligand systems through the use of 2,6-dibromopyridine as a ligand precursor. In addition, we have prepared more flexible ligand systems by employing the starting material 2,6-(dibromomethyl) pyridine to introduce a methylene linker into the pincer ligand. We have metallated these ligand precursors to form copper(I) and (II) complexes. The complexes have already been synthesized and thoroughly characterized. The geometry of some copper(I) complexes allows for studies on the oxygen transfer activity. The copper complexes will be tested for reactivity toward hydrogen peroxide. A detailed description of the syntheses, characterization (X-ray diffraction, electrochemistry, UV-Vis), and reactivity of the SNS copper complexes toward an oxygen atom donor will be presented.

Chemistry Research and SeminarFaculty Mentor: Professor John Miecznikowski

Today in Global HealthUndergraduate: Veronica Suglo ’16Abstract: Global Health is defined as a branch of public health that looks at the various health issues that transcend national boundaries by examining how individuals in low resource areas of the world experience healthcare. In 2005, The Honourable Aileen Carroll, Minister of International Cooperation of Canada, said that “The ultimate goal of global health is to reduce the number of people, importantly children, dying unnecessarily from ill-health and disease.” This presentation will seek to highlight today’s global health issues by examining three of the most devastating global health outbreaks within the last 15 years and analyze efforts made by organizations such as the World Health Organization and the United Nations to resolve these issues as well as propose a new or revised solutions.


Influenza A Virus: Interspecies TransmissionUndergraduate: Elizabeth Szabo ’16Abstract: The factors that contribute to Influenza A interspecies transmission have not been fully understood. With several cases of interspecies transmission of avian and swine viruses, understanding factors than can lead to interspecies transmission are important, as well as knowing how protected a population is to currently circulating viruses that have the potential to transmit. This study evaluated the role of nonstructural protein 1 (NS1) from different viruses on the expression of the interferon response being a potential factor in interspecies transmission and the protection of a sample of individuals from Lebanon to currently circulating swine viruses. The results of the study suggested that inhibition of the interferon response may not be a leading factor in interspecies transmission. It was also found that the population tested showed low protection against currently circulating swine viruses, which can lead to possible pandemic if the viruses were able to transmit to humans.

Biology Independent ResearchFaculty Mentor: Professor Brian Walker

C. Elegans Dynactin Mutants have Sperm Defects that are Rescued by Mutations to mel-28Undergraduate: Angela Tacinelli ’17Abstract: We have been using the nematode worm Caenorhabditis elegans to study genetic interactions between dnc-1 and mel-28 in animals. The dnc-1 gene encodes a component of dynactin, and dnc-1 mutant animals display an abnormally small brood size caused by low fertilization rates. The mel-28 gene encodes a nuclear pore component that is required for early embryogenesis. Reciprocal crosses between dnc-1 mutant and wild-type animals suggest that the fertilization defect in dnc-1 mutants is caused by faulty sperm. Disrupting the mel-28 gene rescues the sperm defect in dnc-1 mutant males, suggesting that in normal animals mel-28 function opposes dnc-1 function. Dissections of sperm from dnc-1 mutant males revealed that sperm activate prematurely and this could contribute to the fertilization defect. This study is the first to show that dynactin and mel-28 contribute to sperm function and could reveal a novel mechanism whereby activation of sperm is regulated.

Biology Independent ResearchFaculty Mentor: Professor Anita Fernandez

Adult Attachment Style as a Predictor of Intimate Partner Violence, Depressive, and Trauma Symptoms in College Dating Relationships Undergraduate: Margaret Trosin ’16Abstract: This study examines adult attachment styles and its relationship to Intimate Partner Violence (IPV), depression, and early trauma symptoms in college dating relationships. The data will analyze attachment styles as a predictor of IPV perpetration and victimization, depressive symptoms, and trauma symptoms in undergraduates at Fairfield University. This is a quasi-experimental design, and four ANOVAs will be conducted: with attachment style as the independent variable, and perpetration of IPV, victimization of IPV, depressive symptoms, and early trauma symptoms as the dependent variables. Follow-up testing will be conducted in significant differences present themselves.


Characterization of a Genetic Network Affecting Fertility in the Nematode Worm C. ElegansUndergraduate: Gabriela Vida ’16Abstract: We are interested in understanding genetic interactions that affect fertility in the nematode Caenorhabditis elegans. Specifically we have been studying dhc-1, which encodes a component of the molecular motor dynein, dnc-1, which encodes a dynactin subunit thought to regulate dynein, and mel-28, which encodes a nuclear pore component. Although mel-28 and dhc-1 single mutants have a normal brood size, mel-28;dhc-1 double mutants show severely reduced fertility, suggesting that normally mel-28 and dhc-1 act cooperatively to promote fertility. dnc-1 mutants have a sperm defect that is rescued by mutations to mel-28, suggesting that dnc-1 and mel-28 have opposing functions in sperm. Next we generated the mel-28;dhc-1;dnc-1 triple mutant and studied its brood size and sperm function. Our results suggest that the mel-28;dnc-1 interaction in sperm is independent of dhc-1 function but that defects to dnc-1 mitigate the severe reduction in brood size caused by simultaneous loss of dhc- 1 and mel-28.

Biology Independent ResearchFaculty Mentor: Professor Anita Fernandez

Investigating Independent Origins of Aurora Kinase B in Nematodes and InsectsUndergraduate: Wathone ’17Abstract: Aurora kinases A and B are proteins that play a vital role in cell division and much research has been dedicated to understanding their function and expression patterns. However, a majority of this research has been based on higher metazoans such as vertebrates. We have continued our previous research on the origin of aurora kinase genes in invertebrates in order to gain some insight into their origins and functional diversification. Our previous research indicated that all invertebrate animals have one copy of Aurora Kinase A, while only nematodes and insects seem to have both Aurora Kinase A and B. This led us to postulate that Aurora Kinase B originated independently along each of these two lineages. We have continued our research by determining the relative selection pressure on these genes over a range of vertebrate lineages in order to better understand the mechanisms by which they originated and continue to evolve.

Biology Independent ResearchFaculty Mentor: Professor Ashley Byun

Office of Academic Affairs

research and creative accomplishments symposium...welcome to the 2016 research and creative...

Documents