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    Regional Anaesthesia&

    Temperature ControlAizat

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    Definition

    Techniques of abolishing pain using localanaesthetic agents as opposed to generalanaesthesia.

    Drugs that produce reversible conduction blockade of impulses along central &peripheral nerves producing ANS, sensoryblockade and skeletal muscle paralysis in thearea innervated by affected nerve

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    Types

    REGIONALANAESTHESIA

    TOPICAL CENTRALNERVE BLOCK

    SPINAL

    ANAESTHESIA

    EPIDURAL

    ANAESTHESIA

    PERIPHERALNERVE BLOCK

    PLEXUS BLOCK SINGLE NERVE

    BLOCK

    INTRAVENOUSREGIONAL

    (BIER BLOCK)

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    Aim

    Provide anesthesia for a surgical procedure

    Provide analgesia pre& post-operatively orduring labour and delivery Diagnosis or therapy for patients with chronic

    pain syndromes

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    LA agent

    Esters Procaine, chloropropaine, tetracaine,amethocaine, cocaine

    Amides lignocaine, etidocaine, mepivacaine,bupivacaine,ropivacaine

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    DRUGS Lignocaine (USA Lidocaine)

    Presentation Clear aq solution lidocaine HCL Plain 0.5%(local infiltration, IVRA ), 1%, 2%(nerve blocks,

    extradural anaesthesia) with adrenaline 1:200 000

    Use of adrenaline: Vasoconstiction at site of injection rate of

    absorption, systemic toxicity, duration of action Gel 2% with or without chlorhexidine

    Clinical : onset in 2-20min; duration 60-120min Recommended max dose 1-3mg/kg (7mg/kg with adrenaline) How to prepare

    Lignocaine concn : O.5%: 5mg/ml, 1%: 10mg/ml,2%:20mg/ml

    E.g: 70kg 210mg : do not use more than 10ml of 2%lignocaine

    C/I : Do not use with adrenaline in end arterial supply (fingers,toes, pinna, penis and nose)

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    Bupivacaine Presentation clear colourless, aq solution

    (bupivacaine hydrochloride ) Plain (0.25%, 0.5%, 0.75%) With 1:200 000 (5g/ml ) adrenaline Heavy 0.5% with 80mg/ml dextrose ( SG 1.026)

    Recommended max dose 2mg/kg (150mg plus up to50mg 2 hourly subsequently)

    Clinical- onset within 10-20min, duration of action 4-8hrs. 4X as potent as lidocaine, propensity forcardiotoxicity

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    ADVANTAGES

    Conscious patients assist in positioning early warning of adverse effects avoid airway manipulation & complications

    Good quality block in term of motor and sensory adequate as per surgical requirement surgical / hormonal / psychological stress

    Less post operative complications less sedated less nausea / vomiting reduce atelectasis pneumonia reduce risk of dvt

    early oral intake

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    DISADVANTAGES

    Patients anxiety increased sympathetic tone unwanted psychological stress

    Technically difficult procedure Co-operation from patients are required Abnormal sensation :

    paraesthesia / hyperaesthesia

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    COMPLICATIONS

    Allergic reaction (rare

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    Topical Anesthesia

    Application of local anesthetic to mucous membrane- cornea, nasal / oral mucosa

    Uses : absorb into dermis and block the nerve end awake oral, nasal intubation, superficial surgical procedure

    Advantages : technically easy minimal equipment

    Disadvantages : potential for large doses leading to toxicity

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    Local/Field Anesthesia

    Application of local subcutaneously to anesthetisedistal nerve endings

    Uses: Suturing, minor superficial surgery, line placement, more

    extensive surgery with sedation Advantages:

    minimal equipment, technically easy, rapid onset Disadvantages:

    potential for toxicity if large field

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    Forehead block

    2 nerves from superior orbital marginSupraorbital n: 2.5cm from midlineSupratrochlear n: upper medial corner of orbit

    Insert needle from eyebrow midline directlaterally

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    Auricular block

    Nerve: auriculotemporal, greater auricular and lesseroccipital

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    Peripheral Nerve Block Injecting local anesthetic near the course of a named

    nerve Uses:

    Surgical procedures in the distribution of the blockednerve Advantages:

    relatively small dose of local anesthetic to cover large area;rapid onset

    Disadvantages: technical complexity, neuropathy

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    Wrist block

    Median nerve : lies superficially between palmaris longus and FCRUlnar nerve : lies between FCU and ulnar arteryRadial nerve: over radial styloid up to extensor surface

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    Digital nerve block

    Web space approach. 2 dorsal & 2 palmar. NEVER use adrenaline

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    Ankle block

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    Saphenous nerve: ant and just above medial malleolusSuperficial peroneal nerve: above the ankle joint from anterior border of tibia to lateralmalleolusDeep peroneal n: above ankle joint between tibialis ant tendon and ext hallucis longusSural n: Lateral to achilles tendon to lateral malleolusTibia n: Medial to achilles tendon to lateral PTA (by palpation)

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    Femoral block

    Femoral nerve : Lateral to artery under inguinal ligament

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    Plexus Blockade Injection of local anesthetic

    adjacent to a plexus,e.gcervical, brachial or lumbarplexus

    Uses : surgical anesthesia or post-operative analgesia in the

    distribution of the plexus Advantages:

    large area of anesthesia withrelatively large dose of agent

    Disadvantages: technically complex, potential

    for toxicity and neuropathy

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    Biers block (IVRA) Indication : M&R of forearm # Drugs: 10ml of 1% lignocaine

    Dosage :0.4ml/kg(2mg/kg), onset 3mins Technique

    V/S monitoring & IV branula on bothhands

    Torniquet affevted limb: 50-100mmhgabove SBP

    Elevate hand above heart beofretorniquet

    Confirm dissappearnace of radial pulsebefore injecting LA

    Don t deflate cuff within

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    Spinal vs Epidural

    SPINAL EPIDURAL

    site ofadministration :

    subarachnoid space CSF (+)

    extra dural space --loss of resistance

    technically : easierSpinal needle

    LOR

    more difficultTuohy needle

    CSF fluid

    failure rate : low high

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    Spinal vs Epidural

    SPINAL EPIDURAL

    onset : Fast Slow

    duration : 2 to 2.5 hours( flexible)

    flexible

    level : lumbar ; sacral cervical to caudal

    volume of LA : small

    1.0 to 3.0 mls

    large

    5.0 to 30 mls

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    Temperature control

    Hypothalamus is the body thermostat Normal core temp: 37C (if taken internally)

    36.8 0.4C (98.2 0.7F) in oral,axilla&rectal Ideal site : Pulmonary artery (gold standard)

    Using thermistor cathether Blood mix from skin to viscera

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    Take home message

    LA produce reversible conduction blockage byinhibiting passage of Na ions through the ionselective NA channel at the nerve membrane.

    Lignocaine 1-3mg/kg, 2% = 20mg/ml Serious systemic effect are cardiac arrythmias

    and convulsion Identify anatomy first before giving LA Hypothalamus controls the body temp