reasons of foot ulcer

15
Table 2 Clinical Classification of Diabetic Foot Infection CLINICAL MANIFESTATIONS OF INFECTION INFECTION SEVERITY Wound lacking purulence or any manifestations of inflammation (i.e., erythema, pain, tenderness, warmth, or induration) Not infected Presence of purulence andor two or more manifestations of inflammation, but any cellulitis or erythema e!tends 2 cm or less around the ulcer" infection is limited to the skin or superficial subcutaneous tissues" no other local complications or systemic illness #ild $nfection (purulence andor two or more manifestations of inflammation) in a patient who is systemically well and metabolically stable, but who has at least one of the following characteristics% cellulitis e!tending more than 2 cm around the ulcer" lymphangitic streaking" spread beneath the superficial fascia" deep tissue abscess" gangrene" in&ol&ement of muscle, tendon, 'oint, or bone #oderate $nfection (purulence andor two or more manifestations of inflammation) in a patient with systemic to!icity or metabolic instability (e.g., fe&er, chills, tachycardia, hypotension, confusion, &omiting, leukocytosis, acidosis, se&ere hyperglycemia, aotemia) e&ere  Adapted from Lips ky BA, B erendt A, Deery G, et al., for the Infect ious Diseases Society of America. Diag nosis and treatment of diabetic foot infections. *lin $nfect +is. 2!"#$%&'()$! . Table Empiric Antibiotic Regimens for Treatment of Diabetic Foot Infection

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Page 1: Reasons of Foot Ulcer

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 115

Table 2

Clinical Classification of Diabetic Foot Infection

CLINICAL MANIFESTATIONS OF INFECTION

INFECTION

SEVERITY

Wound lacking purulence or any manifestations of inflammation(ie erythema pain tenderness warmth or induration)

Notinfected

Presence of purulence andor two or more manifestations ofinflammation but any cellulitis or erythema etends 2 cm orless around the ulcer infection is limited to the skin orsuperficial subcutaneous tissues no other local complicationsor systemic illness

ild

$nfection (purulence andor two or more manifestations ofinflammation) in a patient who is systemically well andmetabolically stable but who has at least one of the followingcharacteristics cellulitis etending more than 2 cm around theulcer lymphangitic streaking spread beneath the superficialfascia deep tissue abscess gangrene inampolampement of muscletendon oint or bone

oderate

$nfection (purulence andor two or more manifestations of

inflammation) in a patient with systemic toicity or metabolicinstability (eg feamper chills tachycardia hypotensionconfusion ampomiting leukocytosis acidosis seamperehyperglycemia aotemia)

eampere

Adapted from Lipsky BA Berendt A Deery G et al for the Infectious Diseases Society of America Diagnosis

and treatment of diabetic foot infections lin $nfect +is 2$amp()$

Table Empiric Antibiotic Regimens for Treatment of Diabetic Foot Infection

7232019 Reasons of Foot Ulcer

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SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

oft tissue infection

ild (durationof treatmentis one to twoweeks)

+icloacillin -- mg orally fourtimes per day

ral agent of choicefor

ephalein (0efle) -- mgorally four times per day

1or penicillinallergicpatients eceptthose with immediatehypersensitiampityreactions

moicillinclaampulanate(ugmentin) 3452 mg orallytwice per day

6ood option forpolymicrobialinfection

lindamycin (leocin) 7-- to8- mg orally three times perday

Potential crossresistance andemergence ofresistance in

erythromycinresistantStaphylococ cus aureus inducibleresistance in 9

+oycycline (ibramycin) 5--mg orally twice perdayor ulfamethoaoletrimethoprim (actrim) 5lt-3-- mgorally twice per day

=ffectiampe for 9

oderate(duration oftreatment istwo to fourweeksdepending on

7232019 Reasons of Foot Ulcer

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SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

responseadministerorally orparenterallyfollowed byorally)

9iskfactors forpolymicrob

ialinfectionabsentgt

Nafcillin 5 to 2 g $ eampery fourhours

Parenteral drug ofchoice for

efaolin 5 to 2 g $ eampery eighthours

1or penicillinallergicpatients

ancomycin 7- mg per kg $twice per day

Parenteral drug ofchoice for 9

9iskfactors forpolymicrob

ialinfectionpresentgt

mpicillinsulbactam (nasyn) 7g $ four times per day

eftriaone (9ocephin) 5 to 2 g$ once per day plusclindamycin lt-- to A-- mg $ or orally three times per day ormetronidaole (1lagyl) -- mg$ or orally three times per day

or

Beampofloacin (BeampaCuin) -- mg$ or orally once per day plusclindamycin lt-- to A-- mg $ or orally three times per day

oifloacin (ampelo) 8-- mg $

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 415

SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

or orally once per day

=rtapenem ($nampan) 5 g $ onceper day

eampere(duration oftreatment istwo to fourweeksdepending onresponseadministerparenterallythen switch toorally)

iprofloacin (ipro) 8-- mg $twice per day plus clindamycinlt-- to A-- mg $ three timesper day

Piperacillintaobactam (Dosyn)774 to 8-- g $ eampery si toeight hours

$mipenemcilastatin (Primain)-- mg $ four times per day

ancomycin 7- mg per kg $

twice per day plus ciprofloacin8-- mg $ twice per day plusmetronidaole -- mg $ ororally three times per day

ancomycin is the

parenteral drug ofchoice for 9lineolid (Dyampo) lt--mg $ or orally twiceper day ordaptomycin (ubicin)8 mg per kg $ onceper day can also beused for 9seampancomycin forpenicillinallergic

patients

Tigecycline (Tygacil) 5-- mg $loading dose then - mg $twice per day

hould be usedwhen suspectedpolymicrobialinfection including9

7232019 Reasons of Foot Ulcer

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SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

one or oint infection

No residualinfectedtissue

se the aboampe parenteral or oralantibiotic regimens for two tofiampe days

9esidualinfectedtissue only

se the aboampe parenteral or oralantibiotic regimens for two tofour weeks

9esidualinfectedampiable bone

$nitially use the aboampeparenteral antibiotics followedby oral antibiotics for four to siweeks

9esidualinfected deadbone

$nitially use the aboampeparenteral antibiotics followedby oral antibiotics for eight to 52weeks

I + intraenously -SA + methicillinresistant taphylococcus aureus -SSA +methicillinsusceptible aureusgt isk factors for polymicrobial infection include chronic ulcers recent antibioticuse and foot ischemia or gangreneInformation from references and 2 through

WOUND MANAGEMENT

The wound should be dressed to allow for careful inspection for eampidence of healing and

early identification of new necrotic tissue Necrotic or unhealthy tissue should be

debrided preferably surgically or with topical debriding agents 9emoamping pressure from

the foot wound is crucial for healing7 and can be achieamped through total contact casting

remoampable cast walkers and amparious ambulatory braces splints modified halfshoes

and sandals7lt =dema of the legs can delay wound healing controlling edema with leg

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 615

eleampation compression stockings or a pneumatic pedal compression deampice enhances

the healing process74 =ampidence of resolution of infection includes formation of

granulation tissue absence of necrotic tissue and closing of the wound $f osteomyelitis

is present signs of healing include a drop in =9 and loss of increased uptake on

nuclear scan

Topical debriding agents

Topical debriding agents are chemicals that are used locally to clean an open wound by

removing foreign material and dead tissue so that the wound heals without increased

risk of infection This makes the healing faster

See the following link

httpcidoxfordjournalsorgcontent41101373full

BrandDrug

FormPacking

Trade

Price

RPrice

(Rs)

LEFLOX [Levofloxacin5mgml] Inf 100ml 16575 19500

LEFLOX [Levofloxacin75mgml] Inf 150ml 21505 25300

LEFLOX [Levofloxacin250mg] a 10 1013 1190

LEFLOX [Levofloxacin500mg] a 10 17765 20900

LEFLOX [Levofloxacin750mg] a 10 2$60 2950

amplic on )an+ ame -o vie i- l-ena-e )an+ an+ In+ica-ionIndications eia-o -ac- infec-ion4 ini-i4

221 Alternate Brands Found

AlternateBrands

ManuactrerMnReresentatie

PackingR Price

(Rs)

EO) )E amp8EI 8 1x10lt $1600

=OLOX =O 8ampEgtIampL

L 10 20000

LI EO 8 10 1000

LIXI

LI ampO)IE

8ampEgtIampL

L

1x10 27000

LOIampLLIampE8ampEgtIampL

L

10 $0000

O AI8 8ampEgtIampL 10 2$$00

ILIX I EampIE 10 $1600

ampOFLOX ampO L)OOIE

LIIE 10 1000

7232019 Reasons of Foot Ulcer

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BX gtB 8ampEgtIampL 10 20500

XOLE CI 8ampEgtIampL

IgtIE 1x10 25000

XOLOX DI 8ampgtIampL 10 26000

)ELEO EO 8 10 1790

)ELOX )EO 8ampEgtIampL 10 25000

)EXgt8I8ampEgtIampL

L

10 1500

)OI BEIamp=

8ampEgtIampL 10 19500

ampLE ampLEX 8ampEgtIampL

L 10 29000

ampELO ampI 8ampEgtIampL 10 $1600

ampIDgtI ampIFIamp 8ampEgtIampL

L 10 17200

ampI 8ILO 8

LIIE 10 700

ampOampgt CE8 8Eamp

L 10 21900

ampgt)amp amp8COO C= 10 1000

ampgtIF )OI

8ampEgtIampL 10 25000

ampOXI 8CL

8ampEgtIampL 10lt $1600

ELOampI 8 8EL8 =I

L 10 2000

DgtI )E 8OO

=I L 10 17000

EFFIFLOX I 8ampEgtIampL

L 10 20000

EFFIDgtI BBOOB =I

L 10 1500

EIOampI EO 8ampEgtIampL 10lt $1600

ELLE EL L)OOIE

L 10 1500

EOEL EOamp8 8ampEgtIampL 1x10 $0000

EXOgtE EIgtE L)OOIE=I L

10 22500

EXIamp 8ampE

L)OOIE L 10 20000

F OXampI )IO L) L 10 2000

FLEO E8 8 10 1500

FEELIX AEE8ampEgtIampL

10 30000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 815

L

FILIE )IO 8 10 21000

FLOXE EFOCE amp8EIampL

IgtIE L 10 1500

FLOXOLE

LIgt

8ampEgtIampL L

10 17500

FOEL =I 8ampEgtIampL

Ogtamp L 1x10lt 39000

FLOE B FIEL

8ampEgtIampL 10 $1529

ELEO )OO=E 8ampEgtIampL

L)OOIE = L 10 17000

8EampO =C 8EX L 10 $1600

8EO LIE 8 1x10lt $1600

8E )IOE 8 10lt $1600

IFEampgtE amp8 8ampEgtIampL

O8 L 1x10lt $1600

IFLOX gtLE 8ampEgtIampL 10 27000

IOIamp gtB 8

L 10 25000

AEELEXI

AB

8ampEgtIampL

L

10 $1600

=FLOX X EEE 8ampEgtIampL 10 30000

=OFLOX

=O8I

8ampEgtIampL

L

1x10 32000

=EOX )LOO 8ampEgtIampL

L 10 $2000

=IampI 8OI 8ampEgtIampL

L)OOIE 10 $1600

=Lgt Oamp= 8ampEgtIampL 1x10lt $0000

=O)EXI =O)Eamp 8ampL 10 32000

LIFLOX CampO=

8ampEgtIampL 10lt $1600

LILOX 8OOD 8ampEgtIampL 10 19000

LCE EIC L) L 10 1000Lamp 8I8 D IEIOL 10 26000

LE$ B FIEL

8ampEgtIampL 10 $1600

LEampI LO 8ampEgtIampL 10 16000

LEEX OO 8 10 $1600

LEE) FEOC IEIOL8ampEgtIampL

10 $1600

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 915

L

LEFEX 8OOD 8ampEgtIampL 10 1000

LEFLOampI OLFIE amp8E8

L 10 32000

LEFLOEamp 8Eamp =I

L 10 19500

LEFIL BELL BELL 8

L 10lt 17500

LEFOXI EgtO 8 L 10 $1600

LEE )IOEIamp =I

L 10 17000

LEO =I 8ampEgtIampL 1x10 $1600

LEOampI E 8ampEgtIampL

L 10 25000

LEOFLOX )O 8ampEgtIampL

L 10 20000

LEO EIgtE L)OOIE

=I L 10 $1600

LEOE BELL)OE 8amp8E

)IOLOIampL 10 27000

LEOI EI= LIIE 10 12000

LEOX ampE

8ampEgtIampL 2x5 23000

LEIamp LO)L 8ampEgtIampL 10 $1600

LEDgtI )E 8OO

=I L 10 67100

LE I 8ampEgtIampL 10lt $0000LEI

EE 8ampEgtIampL

L 10lt $0000

LECE EL 8 L 10 $2000

LEEE IOE=

8ampEgtIampL 10 15000

LEE E8 EIampIE ampO 10 27000

LEILOX EXgt 8 L 10 $1600

LEIE 8 IE

LIIE 10 2$000

LELO ELI8 8ampEgtIampL

IgtIE 10 $1600

LEO FEOCO L)OOIE

L 10 23000

LEO F OL L)OOIE

L 10 19000

LEO) )IOEX 8ampEgtIampL 1x10lt $1600

LEOampI 8EL 8ampgtEgtIampL

L 10 17000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1015

7232019 Reasons of Foot Ulcer

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7232019 Reasons of Foot Ulcer

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Page 2: Reasons of Foot Ulcer

7232019 Reasons of Foot Ulcer

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SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

oft tissue infection

ild (durationof treatmentis one to twoweeks)

+icloacillin -- mg orally fourtimes per day

ral agent of choicefor

ephalein (0efle) -- mgorally four times per day

1or penicillinallergicpatients eceptthose with immediatehypersensitiampityreactions

moicillinclaampulanate(ugmentin) 3452 mg orallytwice per day

6ood option forpolymicrobialinfection

lindamycin (leocin) 7-- to8- mg orally three times perday

Potential crossresistance andemergence ofresistance in

erythromycinresistantStaphylococ cus aureus inducibleresistance in 9

+oycycline (ibramycin) 5--mg orally twice perdayor ulfamethoaoletrimethoprim (actrim) 5lt-3-- mgorally twice per day

=ffectiampe for 9

oderate(duration oftreatment istwo to fourweeksdepending on

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 315

SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

responseadministerorally orparenterallyfollowed byorally)

9iskfactors forpolymicrob

ialinfectionabsentgt

Nafcillin 5 to 2 g $ eampery fourhours

Parenteral drug ofchoice for

efaolin 5 to 2 g $ eampery eighthours

1or penicillinallergicpatients

ancomycin 7- mg per kg $twice per day

Parenteral drug ofchoice for 9

9iskfactors forpolymicrob

ialinfectionpresentgt

mpicillinsulbactam (nasyn) 7g $ four times per day

eftriaone (9ocephin) 5 to 2 g$ once per day plusclindamycin lt-- to A-- mg $ or orally three times per day ormetronidaole (1lagyl) -- mg$ or orally three times per day

or

Beampofloacin (BeampaCuin) -- mg$ or orally once per day plusclindamycin lt-- to A-- mg $ or orally three times per day

oifloacin (ampelo) 8-- mg $

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 415

SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

or orally once per day

=rtapenem ($nampan) 5 g $ onceper day

eampere(duration oftreatment istwo to fourweeksdepending onresponseadministerparenterallythen switch toorally)

iprofloacin (ipro) 8-- mg $twice per day plus clindamycinlt-- to A-- mg $ three timesper day

Piperacillintaobactam (Dosyn)774 to 8-- g $ eampery si toeight hours

$mipenemcilastatin (Primain)-- mg $ four times per day

ancomycin 7- mg per kg $

twice per day plus ciprofloacin8-- mg $ twice per day plusmetronidaole -- mg $ ororally three times per day

ancomycin is the

parenteral drug ofchoice for 9lineolid (Dyampo) lt--mg $ or orally twiceper day ordaptomycin (ubicin)8 mg per kg $ onceper day can also beused for 9seampancomycin forpenicillinallergic

patients

Tigecycline (Tygacil) 5-- mg $loading dose then - mg $twice per day

hould be usedwhen suspectedpolymicrobialinfection including9

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 515

SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

one or oint infection

No residualinfectedtissue

se the aboampe parenteral or oralantibiotic regimens for two tofiampe days

9esidualinfectedtissue only

se the aboampe parenteral or oralantibiotic regimens for two tofour weeks

9esidualinfectedampiable bone

$nitially use the aboampeparenteral antibiotics followedby oral antibiotics for four to siweeks

9esidualinfected deadbone

$nitially use the aboampeparenteral antibiotics followedby oral antibiotics for eight to 52weeks

I + intraenously -SA + methicillinresistant taphylococcus aureus -SSA +methicillinsusceptible aureusgt isk factors for polymicrobial infection include chronic ulcers recent antibioticuse and foot ischemia or gangreneInformation from references and 2 through

WOUND MANAGEMENT

The wound should be dressed to allow for careful inspection for eampidence of healing and

early identification of new necrotic tissue Necrotic or unhealthy tissue should be

debrided preferably surgically or with topical debriding agents 9emoamping pressure from

the foot wound is crucial for healing7 and can be achieamped through total contact casting

remoampable cast walkers and amparious ambulatory braces splints modified halfshoes

and sandals7lt =dema of the legs can delay wound healing controlling edema with leg

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 615

eleampation compression stockings or a pneumatic pedal compression deampice enhances

the healing process74 =ampidence of resolution of infection includes formation of

granulation tissue absence of necrotic tissue and closing of the wound $f osteomyelitis

is present signs of healing include a drop in =9 and loss of increased uptake on

nuclear scan

Topical debriding agents

Topical debriding agents are chemicals that are used locally to clean an open wound by

removing foreign material and dead tissue so that the wound heals without increased

risk of infection This makes the healing faster

See the following link

httpcidoxfordjournalsorgcontent41101373full

BrandDrug

FormPacking

Trade

Price

RPrice

(Rs)

LEFLOX [Levofloxacin5mgml] Inf 100ml 16575 19500

LEFLOX [Levofloxacin75mgml] Inf 150ml 21505 25300

LEFLOX [Levofloxacin250mg] a 10 1013 1190

LEFLOX [Levofloxacin500mg] a 10 17765 20900

LEFLOX [Levofloxacin750mg] a 10 2$60 2950

amplic on )an+ ame -o vie i- l-ena-e )an+ an+ In+ica-ionIndications eia-o -ac- infec-ion4 ini-i4

221 Alternate Brands Found

AlternateBrands

ManuactrerMnReresentatie

PackingR Price

(Rs)

EO) )E amp8EI 8 1x10lt $1600

=OLOX =O 8ampEgtIampL

L 10 20000

LI EO 8 10 1000

LIXI

LI ampO)IE

8ampEgtIampL

L

1x10 27000

LOIampLLIampE8ampEgtIampL

L

10 $0000

O AI8 8ampEgtIampL 10 2$$00

ILIX I EampIE 10 $1600

ampOFLOX ampO L)OOIE

LIIE 10 1000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 715

BX gtB 8ampEgtIampL 10 20500

XOLE CI 8ampEgtIampL

IgtIE 1x10 25000

XOLOX DI 8ampgtIampL 10 26000

)ELEO EO 8 10 1790

)ELOX )EO 8ampEgtIampL 10 25000

)EXgt8I8ampEgtIampL

L

10 1500

)OI BEIamp=

8ampEgtIampL 10 19500

ampLE ampLEX 8ampEgtIampL

L 10 29000

ampELO ampI 8ampEgtIampL 10 $1600

ampIDgtI ampIFIamp 8ampEgtIampL

L 10 17200

ampI 8ILO 8

LIIE 10 700

ampOampgt CE8 8Eamp

L 10 21900

ampgt)amp amp8COO C= 10 1000

ampgtIF )OI

8ampEgtIampL 10 25000

ampOXI 8CL

8ampEgtIampL 10lt $1600

ELOampI 8 8EL8 =I

L 10 2000

DgtI )E 8OO

=I L 10 17000

EFFIFLOX I 8ampEgtIampL

L 10 20000

EFFIDgtI BBOOB =I

L 10 1500

EIOampI EO 8ampEgtIampL 10lt $1600

ELLE EL L)OOIE

L 10 1500

EOEL EOamp8 8ampEgtIampL 1x10 $0000

EXOgtE EIgtE L)OOIE=I L

10 22500

EXIamp 8ampE

L)OOIE L 10 20000

F OXampI )IO L) L 10 2000

FLEO E8 8 10 1500

FEELIX AEE8ampEgtIampL

10 30000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 815

L

FILIE )IO 8 10 21000

FLOXE EFOCE amp8EIampL

IgtIE L 10 1500

FLOXOLE

LIgt

8ampEgtIampL L

10 17500

FOEL =I 8ampEgtIampL

Ogtamp L 1x10lt 39000

FLOE B FIEL

8ampEgtIampL 10 $1529

ELEO )OO=E 8ampEgtIampL

L)OOIE = L 10 17000

8EampO =C 8EX L 10 $1600

8EO LIE 8 1x10lt $1600

8E )IOE 8 10lt $1600

IFEampgtE amp8 8ampEgtIampL

O8 L 1x10lt $1600

IFLOX gtLE 8ampEgtIampL 10 27000

IOIamp gtB 8

L 10 25000

AEELEXI

AB

8ampEgtIampL

L

10 $1600

=FLOX X EEE 8ampEgtIampL 10 30000

=OFLOX

=O8I

8ampEgtIampL

L

1x10 32000

=EOX )LOO 8ampEgtIampL

L 10 $2000

=IampI 8OI 8ampEgtIampL

L)OOIE 10 $1600

=Lgt Oamp= 8ampEgtIampL 1x10lt $0000

=O)EXI =O)Eamp 8ampL 10 32000

LIFLOX CampO=

8ampEgtIampL 10lt $1600

LILOX 8OOD 8ampEgtIampL 10 19000

LCE EIC L) L 10 1000Lamp 8I8 D IEIOL 10 26000

LE$ B FIEL

8ampEgtIampL 10 $1600

LEampI LO 8ampEgtIampL 10 16000

LEEX OO 8 10 $1600

LEE) FEOC IEIOL8ampEgtIampL

10 $1600

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 915

L

LEFEX 8OOD 8ampEgtIampL 10 1000

LEFLOampI OLFIE amp8E8

L 10 32000

LEFLOEamp 8Eamp =I

L 10 19500

LEFIL BELL BELL 8

L 10lt 17500

LEFOXI EgtO 8 L 10 $1600

LEE )IOEIamp =I

L 10 17000

LEO =I 8ampEgtIampL 1x10 $1600

LEOampI E 8ampEgtIampL

L 10 25000

LEOFLOX )O 8ampEgtIampL

L 10 20000

LEO EIgtE L)OOIE

=I L 10 $1600

LEOE BELL)OE 8amp8E

)IOLOIampL 10 27000

LEOI EI= LIIE 10 12000

LEOX ampE

8ampEgtIampL 2x5 23000

LEIamp LO)L 8ampEgtIampL 10 $1600

LEDgtI )E 8OO

=I L 10 67100

LE I 8ampEgtIampL 10lt $0000LEI

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L 10lt $0000

LECE EL 8 L 10 $2000

LEEE IOE=

8ampEgtIampL 10 15000

LEE E8 EIampIE ampO 10 27000

LEILOX EXgt 8 L 10 $1600

LEIE 8 IE

LIIE 10 2$000

LELO ELI8 8ampEgtIampL

IgtIE 10 $1600

LEO FEOCO L)OOIE

L 10 23000

LEO F OL L)OOIE

L 10 19000

LEO) )IOEX 8ampEgtIampL 1x10lt $1600

LEOampI 8EL 8ampgtEgtIampL

L 10 17000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1015

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Page 3: Reasons of Foot Ulcer

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SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

responseadministerorally orparenterallyfollowed byorally)

9iskfactors forpolymicrob

ialinfectionabsentgt

Nafcillin 5 to 2 g $ eampery fourhours

Parenteral drug ofchoice for

efaolin 5 to 2 g $ eampery eighthours

1or penicillinallergicpatients

ancomycin 7- mg per kg $twice per day

Parenteral drug ofchoice for 9

9iskfactors forpolymicrob

ialinfectionpresentgt

mpicillinsulbactam (nasyn) 7g $ four times per day

eftriaone (9ocephin) 5 to 2 g$ once per day plusclindamycin lt-- to A-- mg $ or orally three times per day ormetronidaole (1lagyl) -- mg$ or orally three times per day

or

Beampofloacin (BeampaCuin) -- mg$ or orally once per day plusclindamycin lt-- to A-- mg $ or orally three times per day

oifloacin (ampelo) 8-- mg $

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 415

SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

or orally once per day

=rtapenem ($nampan) 5 g $ onceper day

eampere(duration oftreatment istwo to fourweeksdepending onresponseadministerparenterallythen switch toorally)

iprofloacin (ipro) 8-- mg $twice per day plus clindamycinlt-- to A-- mg $ three timesper day

Piperacillintaobactam (Dosyn)774 to 8-- g $ eampery si toeight hours

$mipenemcilastatin (Primain)-- mg $ four times per day

ancomycin 7- mg per kg $

twice per day plus ciprofloacin8-- mg $ twice per day plusmetronidaole -- mg $ ororally three times per day

ancomycin is the

parenteral drug ofchoice for 9lineolid (Dyampo) lt--mg $ or orally twiceper day ordaptomycin (ubicin)8 mg per kg $ onceper day can also beused for 9seampancomycin forpenicillinallergic

patients

Tigecycline (Tygacil) 5-- mg $loading dose then - mg $twice per day

hould be usedwhen suspectedpolymicrobialinfection including9

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 515

SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

one or oint infection

No residualinfectedtissue

se the aboampe parenteral or oralantibiotic regimens for two tofiampe days

9esidualinfectedtissue only

se the aboampe parenteral or oralantibiotic regimens for two tofour weeks

9esidualinfectedampiable bone

$nitially use the aboampeparenteral antibiotics followedby oral antibiotics for four to siweeks

9esidualinfected deadbone

$nitially use the aboampeparenteral antibiotics followedby oral antibiotics for eight to 52weeks

I + intraenously -SA + methicillinresistant taphylococcus aureus -SSA +methicillinsusceptible aureusgt isk factors for polymicrobial infection include chronic ulcers recent antibioticuse and foot ischemia or gangreneInformation from references and 2 through

WOUND MANAGEMENT

The wound should be dressed to allow for careful inspection for eampidence of healing and

early identification of new necrotic tissue Necrotic or unhealthy tissue should be

debrided preferably surgically or with topical debriding agents 9emoamping pressure from

the foot wound is crucial for healing7 and can be achieamped through total contact casting

remoampable cast walkers and amparious ambulatory braces splints modified halfshoes

and sandals7lt =dema of the legs can delay wound healing controlling edema with leg

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 615

eleampation compression stockings or a pneumatic pedal compression deampice enhances

the healing process74 =ampidence of resolution of infection includes formation of

granulation tissue absence of necrotic tissue and closing of the wound $f osteomyelitis

is present signs of healing include a drop in =9 and loss of increased uptake on

nuclear scan

Topical debriding agents

Topical debriding agents are chemicals that are used locally to clean an open wound by

removing foreign material and dead tissue so that the wound heals without increased

risk of infection This makes the healing faster

See the following link

httpcidoxfordjournalsorgcontent41101373full

BrandDrug

FormPacking

Trade

Price

RPrice

(Rs)

LEFLOX [Levofloxacin5mgml] Inf 100ml 16575 19500

LEFLOX [Levofloxacin75mgml] Inf 150ml 21505 25300

LEFLOX [Levofloxacin250mg] a 10 1013 1190

LEFLOX [Levofloxacin500mg] a 10 17765 20900

LEFLOX [Levofloxacin750mg] a 10 2$60 2950

amplic on )an+ ame -o vie i- l-ena-e )an+ an+ In+ica-ionIndications eia-o -ac- infec-ion4 ini-i4

221 Alternate Brands Found

AlternateBrands

ManuactrerMnReresentatie

PackingR Price

(Rs)

EO) )E amp8EI 8 1x10lt $1600

=OLOX =O 8ampEgtIampL

L 10 20000

LI EO 8 10 1000

LIXI

LI ampO)IE

8ampEgtIampL

L

1x10 27000

LOIampLLIampE8ampEgtIampL

L

10 $0000

O AI8 8ampEgtIampL 10 2$$00

ILIX I EampIE 10 $1600

ampOFLOX ampO L)OOIE

LIIE 10 1000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 715

BX gtB 8ampEgtIampL 10 20500

XOLE CI 8ampEgtIampL

IgtIE 1x10 25000

XOLOX DI 8ampgtIampL 10 26000

)ELEO EO 8 10 1790

)ELOX )EO 8ampEgtIampL 10 25000

)EXgt8I8ampEgtIampL

L

10 1500

)OI BEIamp=

8ampEgtIampL 10 19500

ampLE ampLEX 8ampEgtIampL

L 10 29000

ampELO ampI 8ampEgtIampL 10 $1600

ampIDgtI ampIFIamp 8ampEgtIampL

L 10 17200

ampI 8ILO 8

LIIE 10 700

ampOampgt CE8 8Eamp

L 10 21900

ampgt)amp amp8COO C= 10 1000

ampgtIF )OI

8ampEgtIampL 10 25000

ampOXI 8CL

8ampEgtIampL 10lt $1600

ELOampI 8 8EL8 =I

L 10 2000

DgtI )E 8OO

=I L 10 17000

EFFIFLOX I 8ampEgtIampL

L 10 20000

EFFIDgtI BBOOB =I

L 10 1500

EIOampI EO 8ampEgtIampL 10lt $1600

ELLE EL L)OOIE

L 10 1500

EOEL EOamp8 8ampEgtIampL 1x10 $0000

EXOgtE EIgtE L)OOIE=I L

10 22500

EXIamp 8ampE

L)OOIE L 10 20000

F OXampI )IO L) L 10 2000

FLEO E8 8 10 1500

FEELIX AEE8ampEgtIampL

10 30000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 815

L

FILIE )IO 8 10 21000

FLOXE EFOCE amp8EIampL

IgtIE L 10 1500

FLOXOLE

LIgt

8ampEgtIampL L

10 17500

FOEL =I 8ampEgtIampL

Ogtamp L 1x10lt 39000

FLOE B FIEL

8ampEgtIampL 10 $1529

ELEO )OO=E 8ampEgtIampL

L)OOIE = L 10 17000

8EampO =C 8EX L 10 $1600

8EO LIE 8 1x10lt $1600

8E )IOE 8 10lt $1600

IFEampgtE amp8 8ampEgtIampL

O8 L 1x10lt $1600

IFLOX gtLE 8ampEgtIampL 10 27000

IOIamp gtB 8

L 10 25000

AEELEXI

AB

8ampEgtIampL

L

10 $1600

=FLOX X EEE 8ampEgtIampL 10 30000

=OFLOX

=O8I

8ampEgtIampL

L

1x10 32000

=EOX )LOO 8ampEgtIampL

L 10 $2000

=IampI 8OI 8ampEgtIampL

L)OOIE 10 $1600

=Lgt Oamp= 8ampEgtIampL 1x10lt $0000

=O)EXI =O)Eamp 8ampL 10 32000

LIFLOX CampO=

8ampEgtIampL 10lt $1600

LILOX 8OOD 8ampEgtIampL 10 19000

LCE EIC L) L 10 1000Lamp 8I8 D IEIOL 10 26000

LE$ B FIEL

8ampEgtIampL 10 $1600

LEampI LO 8ampEgtIampL 10 16000

LEEX OO 8 10 $1600

LEE) FEOC IEIOL8ampEgtIampL

10 $1600

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 915

L

LEFEX 8OOD 8ampEgtIampL 10 1000

LEFLOampI OLFIE amp8E8

L 10 32000

LEFLOEamp 8Eamp =I

L 10 19500

LEFIL BELL BELL 8

L 10lt 17500

LEFOXI EgtO 8 L 10 $1600

LEE )IOEIamp =I

L 10 17000

LEO =I 8ampEgtIampL 1x10 $1600

LEOampI E 8ampEgtIampL

L 10 25000

LEOFLOX )O 8ampEgtIampL

L 10 20000

LEO EIgtE L)OOIE

=I L 10 $1600

LEOE BELL)OE 8amp8E

)IOLOIampL 10 27000

LEOI EI= LIIE 10 12000

LEOX ampE

8ampEgtIampL 2x5 23000

LEIamp LO)L 8ampEgtIampL 10 $1600

LEDgtI )E 8OO

=I L 10 67100

LE I 8ampEgtIampL 10lt $0000LEI

EE 8ampEgtIampL

L 10lt $0000

LECE EL 8 L 10 $2000

LEEE IOE=

8ampEgtIampL 10 15000

LEE E8 EIampIE ampO 10 27000

LEILOX EXgt 8 L 10 $1600

LEIE 8 IE

LIIE 10 2$000

LELO ELI8 8ampEgtIampL

IgtIE 10 $1600

LEO FEOCO L)OOIE

L 10 23000

LEO F OL L)OOIE

L 10 19000

LEO) )IOEX 8ampEgtIampL 1x10lt $1600

LEOampI 8EL 8ampgtEgtIampL

L 10 17000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1015

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1115

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1215

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1315

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1415

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1515

Page 4: Reasons of Foot Ulcer

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 415

SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

or orally once per day

=rtapenem ($nampan) 5 g $ onceper day

eampere(duration oftreatment istwo to fourweeksdepending onresponseadministerparenterallythen switch toorally)

iprofloacin (ipro) 8-- mg $twice per day plus clindamycinlt-- to A-- mg $ three timesper day

Piperacillintaobactam (Dosyn)774 to 8-- g $ eampery si toeight hours

$mipenemcilastatin (Primain)-- mg $ four times per day

ancomycin 7- mg per kg $

twice per day plus ciprofloacin8-- mg $ twice per day plusmetronidaole -- mg $ ororally three times per day

ancomycin is the

parenteral drug ofchoice for 9lineolid (Dyampo) lt--mg $ or orally twiceper day ordaptomycin (ubicin)8 mg per kg $ onceper day can also beused for 9seampancomycin forpenicillinallergic

patients

Tigecycline (Tygacil) 5-- mg $loading dose then - mg $twice per day

hould be usedwhen suspectedpolymicrobialinfection including9

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 515

SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

one or oint infection

No residualinfectedtissue

se the aboampe parenteral or oralantibiotic regimens for two tofiampe days

9esidualinfectedtissue only

se the aboampe parenteral or oralantibiotic regimens for two tofour weeks

9esidualinfectedampiable bone

$nitially use the aboampeparenteral antibiotics followedby oral antibiotics for four to siweeks

9esidualinfected deadbone

$nitially use the aboampeparenteral antibiotics followedby oral antibiotics for eight to 52weeks

I + intraenously -SA + methicillinresistant taphylococcus aureus -SSA +methicillinsusceptible aureusgt isk factors for polymicrobial infection include chronic ulcers recent antibioticuse and foot ischemia or gangreneInformation from references and 2 through

WOUND MANAGEMENT

The wound should be dressed to allow for careful inspection for eampidence of healing and

early identification of new necrotic tissue Necrotic or unhealthy tissue should be

debrided preferably surgically or with topical debriding agents 9emoamping pressure from

the foot wound is crucial for healing7 and can be achieamped through total contact casting

remoampable cast walkers and amparious ambulatory braces splints modified halfshoes

and sandals7lt =dema of the legs can delay wound healing controlling edema with leg

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 615

eleampation compression stockings or a pneumatic pedal compression deampice enhances

the healing process74 =ampidence of resolution of infection includes formation of

granulation tissue absence of necrotic tissue and closing of the wound $f osteomyelitis

is present signs of healing include a drop in =9 and loss of increased uptake on

nuclear scan

Topical debriding agents

Topical debriding agents are chemicals that are used locally to clean an open wound by

removing foreign material and dead tissue so that the wound heals without increased

risk of infection This makes the healing faster

See the following link

httpcidoxfordjournalsorgcontent41101373full

BrandDrug

FormPacking

Trade

Price

RPrice

(Rs)

LEFLOX [Levofloxacin5mgml] Inf 100ml 16575 19500

LEFLOX [Levofloxacin75mgml] Inf 150ml 21505 25300

LEFLOX [Levofloxacin250mg] a 10 1013 1190

LEFLOX [Levofloxacin500mg] a 10 17765 20900

LEFLOX [Levofloxacin750mg] a 10 2$60 2950

amplic on )an+ ame -o vie i- l-ena-e )an+ an+ In+ica-ionIndications eia-o -ac- infec-ion4 ini-i4

221 Alternate Brands Found

AlternateBrands

ManuactrerMnReresentatie

PackingR Price

(Rs)

EO) )E amp8EI 8 1x10lt $1600

=OLOX =O 8ampEgtIampL

L 10 20000

LI EO 8 10 1000

LIXI

LI ampO)IE

8ampEgtIampL

L

1x10 27000

LOIampLLIampE8ampEgtIampL

L

10 $0000

O AI8 8ampEgtIampL 10 2$$00

ILIX I EampIE 10 $1600

ampOFLOX ampO L)OOIE

LIIE 10 1000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 715

BX gtB 8ampEgtIampL 10 20500

XOLE CI 8ampEgtIampL

IgtIE 1x10 25000

XOLOX DI 8ampgtIampL 10 26000

)ELEO EO 8 10 1790

)ELOX )EO 8ampEgtIampL 10 25000

)EXgt8I8ampEgtIampL

L

10 1500

)OI BEIamp=

8ampEgtIampL 10 19500

ampLE ampLEX 8ampEgtIampL

L 10 29000

ampELO ampI 8ampEgtIampL 10 $1600

ampIDgtI ampIFIamp 8ampEgtIampL

L 10 17200

ampI 8ILO 8

LIIE 10 700

ampOampgt CE8 8Eamp

L 10 21900

ampgt)amp amp8COO C= 10 1000

ampgtIF )OI

8ampEgtIampL 10 25000

ampOXI 8CL

8ampEgtIampL 10lt $1600

ELOampI 8 8EL8 =I

L 10 2000

DgtI )E 8OO

=I L 10 17000

EFFIFLOX I 8ampEgtIampL

L 10 20000

EFFIDgtI BBOOB =I

L 10 1500

EIOampI EO 8ampEgtIampL 10lt $1600

ELLE EL L)OOIE

L 10 1500

EOEL EOamp8 8ampEgtIampL 1x10 $0000

EXOgtE EIgtE L)OOIE=I L

10 22500

EXIamp 8ampE

L)OOIE L 10 20000

F OXampI )IO L) L 10 2000

FLEO E8 8 10 1500

FEELIX AEE8ampEgtIampL

10 30000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 815

L

FILIE )IO 8 10 21000

FLOXE EFOCE amp8EIampL

IgtIE L 10 1500

FLOXOLE

LIgt

8ampEgtIampL L

10 17500

FOEL =I 8ampEgtIampL

Ogtamp L 1x10lt 39000

FLOE B FIEL

8ampEgtIampL 10 $1529

ELEO )OO=E 8ampEgtIampL

L)OOIE = L 10 17000

8EampO =C 8EX L 10 $1600

8EO LIE 8 1x10lt $1600

8E )IOE 8 10lt $1600

IFEampgtE amp8 8ampEgtIampL

O8 L 1x10lt $1600

IFLOX gtLE 8ampEgtIampL 10 27000

IOIamp gtB 8

L 10 25000

AEELEXI

AB

8ampEgtIampL

L

10 $1600

=FLOX X EEE 8ampEgtIampL 10 30000

=OFLOX

=O8I

8ampEgtIampL

L

1x10 32000

=EOX )LOO 8ampEgtIampL

L 10 $2000

=IampI 8OI 8ampEgtIampL

L)OOIE 10 $1600

=Lgt Oamp= 8ampEgtIampL 1x10lt $0000

=O)EXI =O)Eamp 8ampL 10 32000

LIFLOX CampO=

8ampEgtIampL 10lt $1600

LILOX 8OOD 8ampEgtIampL 10 19000

LCE EIC L) L 10 1000Lamp 8I8 D IEIOL 10 26000

LE$ B FIEL

8ampEgtIampL 10 $1600

LEampI LO 8ampEgtIampL 10 16000

LEEX OO 8 10 $1600

LEE) FEOC IEIOL8ampEgtIampL

10 $1600

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 915

L

LEFEX 8OOD 8ampEgtIampL 10 1000

LEFLOampI OLFIE amp8E8

L 10 32000

LEFLOEamp 8Eamp =I

L 10 19500

LEFIL BELL BELL 8

L 10lt 17500

LEFOXI EgtO 8 L 10 $1600

LEE )IOEIamp =I

L 10 17000

LEO =I 8ampEgtIampL 1x10 $1600

LEOampI E 8ampEgtIampL

L 10 25000

LEOFLOX )O 8ampEgtIampL

L 10 20000

LEO EIgtE L)OOIE

=I L 10 $1600

LEOE BELL)OE 8amp8E

)IOLOIampL 10 27000

LEOI EI= LIIE 10 12000

LEOX ampE

8ampEgtIampL 2x5 23000

LEIamp LO)L 8ampEgtIampL 10 $1600

LEDgtI )E 8OO

=I L 10 67100

LE I 8ampEgtIampL 10lt $0000LEI

EE 8ampEgtIampL

L 10lt $0000

LECE EL 8 L 10 $2000

LEEE IOE=

8ampEgtIampL 10 15000

LEE E8 EIampIE ampO 10 27000

LEILOX EXgt 8 L 10 $1600

LEIE 8 IE

LIIE 10 2$000

LELO ELI8 8ampEgtIampL

IgtIE 10 $1600

LEO FEOCO L)OOIE

L 10 23000

LEO F OL L)OOIE

L 10 19000

LEO) )IOEX 8ampEgtIampL 1x10lt $1600

LEOampI 8EL 8ampgtEgtIampL

L 10 17000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1015

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1115

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1215

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1315

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1415

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 1515

Page 5: Reasons of Foot Ulcer

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 515

SEVERITY OR

EXTENT OF

INFECTION RECOMMENDED THERAPY COMMENTS

one or oint infection

No residualinfectedtissue

se the aboampe parenteral or oralantibiotic regimens for two tofiampe days

9esidualinfectedtissue only

se the aboampe parenteral or oralantibiotic regimens for two tofour weeks

9esidualinfectedampiable bone

$nitially use the aboampeparenteral antibiotics followedby oral antibiotics for four to siweeks

9esidualinfected deadbone

$nitially use the aboampeparenteral antibiotics followedby oral antibiotics for eight to 52weeks

I + intraenously -SA + methicillinresistant taphylococcus aureus -SSA +methicillinsusceptible aureusgt isk factors for polymicrobial infection include chronic ulcers recent antibioticuse and foot ischemia or gangreneInformation from references and 2 through

WOUND MANAGEMENT

The wound should be dressed to allow for careful inspection for eampidence of healing and

early identification of new necrotic tissue Necrotic or unhealthy tissue should be

debrided preferably surgically or with topical debriding agents 9emoamping pressure from

the foot wound is crucial for healing7 and can be achieamped through total contact casting

remoampable cast walkers and amparious ambulatory braces splints modified halfshoes

and sandals7lt =dema of the legs can delay wound healing controlling edema with leg

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 615

eleampation compression stockings or a pneumatic pedal compression deampice enhances

the healing process74 =ampidence of resolution of infection includes formation of

granulation tissue absence of necrotic tissue and closing of the wound $f osteomyelitis

is present signs of healing include a drop in =9 and loss of increased uptake on

nuclear scan

Topical debriding agents

Topical debriding agents are chemicals that are used locally to clean an open wound by

removing foreign material and dead tissue so that the wound heals without increased

risk of infection This makes the healing faster

See the following link

httpcidoxfordjournalsorgcontent41101373full

BrandDrug

FormPacking

Trade

Price

RPrice

(Rs)

LEFLOX [Levofloxacin5mgml] Inf 100ml 16575 19500

LEFLOX [Levofloxacin75mgml] Inf 150ml 21505 25300

LEFLOX [Levofloxacin250mg] a 10 1013 1190

LEFLOX [Levofloxacin500mg] a 10 17765 20900

LEFLOX [Levofloxacin750mg] a 10 2$60 2950

amplic on )an+ ame -o vie i- l-ena-e )an+ an+ In+ica-ionIndications eia-o -ac- infec-ion4 ini-i4

221 Alternate Brands Found

AlternateBrands

ManuactrerMnReresentatie

PackingR Price

(Rs)

EO) )E amp8EI 8 1x10lt $1600

=OLOX =O 8ampEgtIampL

L 10 20000

LI EO 8 10 1000

LIXI

LI ampO)IE

8ampEgtIampL

L

1x10 27000

LOIampLLIampE8ampEgtIampL

L

10 $0000

O AI8 8ampEgtIampL 10 2$$00

ILIX I EampIE 10 $1600

ampOFLOX ampO L)OOIE

LIIE 10 1000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 715

BX gtB 8ampEgtIampL 10 20500

XOLE CI 8ampEgtIampL

IgtIE 1x10 25000

XOLOX DI 8ampgtIampL 10 26000

)ELEO EO 8 10 1790

)ELOX )EO 8ampEgtIampL 10 25000

)EXgt8I8ampEgtIampL

L

10 1500

)OI BEIamp=

8ampEgtIampL 10 19500

ampLE ampLEX 8ampEgtIampL

L 10 29000

ampELO ampI 8ampEgtIampL 10 $1600

ampIDgtI ampIFIamp 8ampEgtIampL

L 10 17200

ampI 8ILO 8

LIIE 10 700

ampOampgt CE8 8Eamp

L 10 21900

ampgt)amp amp8COO C= 10 1000

ampgtIF )OI

8ampEgtIampL 10 25000

ampOXI 8CL

8ampEgtIampL 10lt $1600

ELOampI 8 8EL8 =I

L 10 2000

DgtI )E 8OO

=I L 10 17000

EFFIFLOX I 8ampEgtIampL

L 10 20000

EFFIDgtI BBOOB =I

L 10 1500

EIOampI EO 8ampEgtIampL 10lt $1600

ELLE EL L)OOIE

L 10 1500

EOEL EOamp8 8ampEgtIampL 1x10 $0000

EXOgtE EIgtE L)OOIE=I L

10 22500

EXIamp 8ampE

L)OOIE L 10 20000

F OXampI )IO L) L 10 2000

FLEO E8 8 10 1500

FEELIX AEE8ampEgtIampL

10 30000

7232019 Reasons of Foot Ulcer

httpslidepdfcomreaderfullreasons-of-foot-ulcer 815

L

FILIE )IO 8 10 21000

FLOXE EFOCE amp8EIampL

IgtIE L 10 1500

FLOXOLE

LIgt

8ampEgtIampL L

10 17500

FOEL =I 8ampEgtIampL

Ogtamp L 1x10lt 39000

FLOE B FIEL

8ampEgtIampL 10 $1529

ELEO )OO=E 8ampEgtIampL

L)OOIE = L 10 17000

8EampO =C 8EX L 10 $1600

8EO LIE 8 1x10lt $1600

8E )IOE 8 10lt $1600

IFEampgtE amp8 8ampEgtIampL

O8 L 1x10lt $1600

IFLOX gtLE 8ampEgtIampL 10 27000

IOIamp gtB 8

L 10 25000

AEELEXI

AB

8ampEgtIampL

L

10 $1600

=FLOX X EEE 8ampEgtIampL 10 30000

=OFLOX

=O8I

8ampEgtIampL

L

1x10 32000

=EOX )LOO 8ampEgtIampL

L 10 $2000

=IampI 8OI 8ampEgtIampL

L)OOIE 10 $1600

=Lgt Oamp= 8ampEgtIampL 1x10lt $0000

=O)EXI =O)Eamp 8ampL 10 32000

LIFLOX CampO=

8ampEgtIampL 10lt $1600

LILOX 8OOD 8ampEgtIampL 10 19000

LCE EIC L) L 10 1000Lamp 8I8 D IEIOL 10 26000

LE$ B FIEL

8ampEgtIampL 10 $1600

LEampI LO 8ampEgtIampL 10 16000

LEEX OO 8 10 $1600

LEE) FEOC IEIOL8ampEgtIampL

10 $1600

7232019 Reasons of Foot Ulcer

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LEFLOEamp 8Eamp =I

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LEFIL BELL BELL 8

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LEO =I 8ampEgtIampL 1x10 $1600

LEOampI E 8ampEgtIampL

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LEO F OL L)OOIE

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LEO) )IOEX 8ampEgtIampL 1x10lt $1600

LEOampI 8EL 8ampgtEgtIampL

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eleampation compression stockings or a pneumatic pedal compression deampice enhances

the healing process74 =ampidence of resolution of infection includes formation of

granulation tissue absence of necrotic tissue and closing of the wound $f osteomyelitis

is present signs of healing include a drop in =9 and loss of increased uptake on

nuclear scan

Topical debriding agents

Topical debriding agents are chemicals that are used locally to clean an open wound by

removing foreign material and dead tissue so that the wound heals without increased

risk of infection This makes the healing faster

See the following link

httpcidoxfordjournalsorgcontent41101373full

BrandDrug

FormPacking

Trade

Price

RPrice

(Rs)

LEFLOX [Levofloxacin5mgml] Inf 100ml 16575 19500

LEFLOX [Levofloxacin75mgml] Inf 150ml 21505 25300

LEFLOX [Levofloxacin250mg] a 10 1013 1190

LEFLOX [Levofloxacin500mg] a 10 17765 20900

LEFLOX [Levofloxacin750mg] a 10 2$60 2950

amplic on )an+ ame -o vie i- l-ena-e )an+ an+ In+ica-ionIndications eia-o -ac- infec-ion4 ini-i4

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ManuactrerMnReresentatie

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(Rs)

EO) )E amp8EI 8 1x10lt $1600

=OLOX =O 8ampEgtIampL

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LI EO 8 10 1000

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ILIX I EampIE 10 $1600

ampOFLOX ampO L)OOIE

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7232019 Reasons of Foot Ulcer

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BX gtB 8ampEgtIampL 10 20500

XOLE CI 8ampEgtIampL

IgtIE 1x10 25000

XOLOX DI 8ampgtIampL 10 26000

)ELEO EO 8 10 1790

)ELOX )EO 8ampEgtIampL 10 25000

)EXgt8I8ampEgtIampL

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10 1500

)OI BEIamp=

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ampLE ampLEX 8ampEgtIampL

L 10 29000

ampELO ampI 8ampEgtIampL 10 $1600

ampIDgtI ampIFIamp 8ampEgtIampL

L 10 17200

ampI 8ILO 8

LIIE 10 700

ampOampgt CE8 8Eamp

L 10 21900

ampgt)amp amp8COO C= 10 1000

ampgtIF )OI

8ampEgtIampL 10 25000

ampOXI 8CL

8ampEgtIampL 10lt $1600

ELOampI 8 8EL8 =I

L 10 2000

DgtI )E 8OO

=I L 10 17000

EFFIFLOX I 8ampEgtIampL

L 10 20000

EFFIDgtI BBOOB =I

L 10 1500

EIOampI EO 8ampEgtIampL 10lt $1600

ELLE EL L)OOIE

L 10 1500

EOEL EOamp8 8ampEgtIampL 1x10 $0000

EXOgtE EIgtE L)OOIE=I L

10 22500

EXIamp 8ampE

L)OOIE L 10 20000

F OXampI )IO L) L 10 2000

FLEO E8 8 10 1500

FEELIX AEE8ampEgtIampL

10 30000

7232019 Reasons of Foot Ulcer

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FILIE )IO 8 10 21000

FLOXE EFOCE amp8EIampL

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FLOXOLE

LIgt

8ampEgtIampL L

10 17500

FOEL =I 8ampEgtIampL

Ogtamp L 1x10lt 39000

FLOE B FIEL

8ampEgtIampL 10 $1529

ELEO )OO=E 8ampEgtIampL

L)OOIE = L 10 17000

8EampO =C 8EX L 10 $1600

8EO LIE 8 1x10lt $1600

8E )IOE 8 10lt $1600

IFEampgtE amp8 8ampEgtIampL

O8 L 1x10lt $1600

IFLOX gtLE 8ampEgtIampL 10 27000

IOIamp gtB 8

L 10 25000

AEELEXI

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8ampEgtIampL

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10 $1600

=FLOX X EEE 8ampEgtIampL 10 30000

=OFLOX

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1x10 32000

=EOX )LOO 8ampEgtIampL

L 10 $2000

=IampI 8OI 8ampEgtIampL

L)OOIE 10 $1600

=Lgt Oamp= 8ampEgtIampL 1x10lt $0000

=O)EXI =O)Eamp 8ampL 10 32000

LIFLOX CampO=

8ampEgtIampL 10lt $1600

LILOX 8OOD 8ampEgtIampL 10 19000

LCE EIC L) L 10 1000Lamp 8I8 D IEIOL 10 26000

LE$ B FIEL

8ampEgtIampL 10 $1600

LEampI LO 8ampEgtIampL 10 16000

LEEX OO 8 10 $1600

LEE) FEOC IEIOL8ampEgtIampL

10 $1600

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L

LEFEX 8OOD 8ampEgtIampL 10 1000

LEFLOampI OLFIE amp8E8

L 10 32000

LEFLOEamp 8Eamp =I

L 10 19500

LEFIL BELL BELL 8

L 10lt 17500

LEFOXI EgtO 8 L 10 $1600

LEE )IOEIamp =I

L 10 17000

LEO =I 8ampEgtIampL 1x10 $1600

LEOampI E 8ampEgtIampL

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LEOFLOX )O 8ampEgtIampL

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LEO EIgtE L)OOIE

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LEOE BELL)OE 8amp8E

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LEOI EI= LIIE 10 12000

LEOX ampE

8ampEgtIampL 2x5 23000

LEIamp LO)L 8ampEgtIampL 10 $1600

LEDgtI )E 8OO

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LE I 8ampEgtIampL 10lt $0000LEI

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LECE EL 8 L 10 $2000

LEEE IOE=

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LEE E8 EIampIE ampO 10 27000

LEILOX EXgt 8 L 10 $1600

LEIE 8 IE

LIIE 10 2$000

LELO ELI8 8ampEgtIampL

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LEO FEOCO L)OOIE

L 10 23000

LEO F OL L)OOIE

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LEO) )IOEX 8ampEgtIampL 1x10lt $1600

LEOampI 8EL 8ampgtEgtIampL

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BX gtB 8ampEgtIampL 10 20500

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)ELEO EO 8 10 1790

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)OI BEIamp=

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ampLE ampLEX 8ampEgtIampL

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ampELO ampI 8ampEgtIampL 10 $1600

ampIDgtI ampIFIamp 8ampEgtIampL

L 10 17200

ampI 8ILO 8

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ampOampgt CE8 8Eamp

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ampgt)amp amp8COO C= 10 1000

ampgtIF )OI

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ampOXI 8CL

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ELOampI 8 8EL8 =I

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EFFIFLOX I 8ampEgtIampL

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EFFIDgtI BBOOB =I

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ELLE EL L)OOIE

L 10 1500

EOEL EOamp8 8ampEgtIampL 1x10 $0000

EXOgtE EIgtE L)OOIE=I L

10 22500

EXIamp 8ampE

L)OOIE L 10 20000

F OXampI )IO L) L 10 2000

FLEO E8 8 10 1500

FEELIX AEE8ampEgtIampL

10 30000

7232019 Reasons of Foot Ulcer

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L

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FLOXOLE

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FLOE B FIEL

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ELEO )OO=E 8ampEgtIampL

L)OOIE = L 10 17000

8EampO =C 8EX L 10 $1600

8EO LIE 8 1x10lt $1600

8E )IOE 8 10lt $1600

IFEampgtE amp8 8ampEgtIampL

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IFLOX gtLE 8ampEgtIampL 10 27000

IOIamp gtB 8

L 10 25000

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=Lgt Oamp= 8ampEgtIampL 1x10lt $0000

=O)EXI =O)Eamp 8ampL 10 32000

LIFLOX CampO=

8ampEgtIampL 10lt $1600

LILOX 8OOD 8ampEgtIampL 10 19000

LCE EIC L) L 10 1000Lamp 8I8 D IEIOL 10 26000

LE$ B FIEL

8ampEgtIampL 10 $1600

LEampI LO 8ampEgtIampL 10 16000

LEEX OO 8 10 $1600

LEE) FEOC IEIOL8ampEgtIampL

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7232019 Reasons of Foot Ulcer

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L

LEFEX 8OOD 8ampEgtIampL 10 1000

LEFLOampI OLFIE amp8E8

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LEFLOEamp 8Eamp =I

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LEFIL BELL BELL 8

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LEFOXI EgtO 8 L 10 $1600

LEE )IOEIamp =I

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LEO =I 8ampEgtIampL 1x10 $1600

LEOampI E 8ampEgtIampL

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LEOFLOX )O 8ampEgtIampL

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LEO EIgtE L)OOIE

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LEOE BELL)OE 8amp8E

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LEOI EI= LIIE 10 12000

LEOX ampE

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LEIamp LO)L 8ampEgtIampL 10 $1600

LEDgtI )E 8OO

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LE I 8ampEgtIampL 10lt $0000LEI

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LECE EL 8 L 10 $2000

LEEE IOE=

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LEE E8 EIampIE ampO 10 27000

LEILOX EXgt 8 L 10 $1600

LEIE 8 IE

LIIE 10 2$000

LELO ELI8 8ampEgtIampL

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LEO FEOCO L)OOIE

L 10 23000

LEO F OL L)OOIE

L 10 19000

LEO) )IOEX 8ampEgtIampL 1x10lt $1600

LEOampI 8EL 8ampgtEgtIampL

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8EampO =C 8EX L 10 $1600

8EO LIE 8 1x10lt $1600

8E )IOE 8 10lt $1600

IFEampgtE amp8 8ampEgtIampL

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IFLOX gtLE 8ampEgtIampL 10 27000

IOIamp gtB 8

L 10 25000

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8ampEgtIampL 10lt $1600

LILOX 8OOD 8ampEgtIampL 10 19000

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LEFLOampI OLFIE amp8E8

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LEFLOEamp 8Eamp =I

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LEO =I 8ampEgtIampL 1x10 $1600

LEOampI E 8ampEgtIampL

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LEOFLOX )O 8ampEgtIampL

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LEO EIgtE L)OOIE

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LEOE BELL)OE 8amp8E

)IOLOIampL 10 27000

LEOI EI= LIIE 10 12000

LEOX ampE

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LEIamp LO)L 8ampEgtIampL 10 $1600

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