Quisper in Fieldlab Type 2 Diabetes

André Boorsma

Food intake Blood profile

Genetic profile

body measurements

PDA based on different levels of input

Blood profile

Total Carotenoïds:

Alpha-carotene

Beta-carotene

Beta-cryptoxanthin

Iycopene

Lutein

Zeaxanthin

Omega-3-index

Percentage EPA

en DHA in total

fatty acid fraction.

*Carotenoïds

* fatty acids

* Vitamin D

* Cholesterol

Genetic Profile

FTO

FADS1

TCF7L2

ApoE

MTHFR

A specific variation of this gene is associated with a

greater need to maintain a healthy bodyweight.

People with this specific variation benefit of extra

intake of Omega-3

A specific variation of this gene is associated with an

improvement in weight-loss using a low-fat diet.

Low saturated fat intake is associociated with improvement of

cholesterol levels in people with this genetic variation.

People with this variation have health benefit by extra folate intake

BCMO1 People with a specific variation of this gene can benefit by increasing

their intake of carotenoids found in fruit and vegetables.

FADS1 Persons with a specific gene variation in FADS1

benefit of extra omega-3 fatty acids intake

flaxseed, walnuts

canola oil

salmon,herring

mackarel

sardines

corn oil, soybean oil

cotton seed oil

meat, egg yolk,

dairy

FADS1 (rs174546)

Carriers of the Risk variant (CC)

Omega-3 index (Blood)

Low

Intermediate

Adequate

Check total intake Check total intake Check total intake

Low Sufficient Low Sufficient Low Sufficient

Check dietary intake

Check dietary

intake

Check dietary intake

Check dietary

intake

Check dietary intake

Check dietary

intake

Low Sufficient Low Sufficient Low Sufficient Low Sufficient Low Sufficient Low Sufficient

Message Message Message Message Message Message Message Message Message Message Message Message

L3.4.001

L3.4.002

L3.4.003

L3.4.004

L3.4.005

L3.4.006

L3.4.007

L3.4.008

L3.4.009

L3.4.0010

L3.4.011

L3.4.012

Decision Tree FADS1

Nutritional, Food or lifestyle advice

Food intake genetics fatty acids - blood

7

Iron Intake (Supplements & Food)

LOW RECOMMENDED HIGH

Iron intake from Food

Iron intake from Food

Iron intake from Food

Low Low

Recommended Low

Recommended High

Message No Message No Message No Message No Message No

L3.11.001

L3.11.002

L3.11.007

L3.11.003

L3.11.004

Any Iron from supplements?

No Yes Message No Message No

L3.11.005

L3.11.006

MTHFR (rs1801133)

Carriers of the Risk variant (TT & CT)

Total Folate Intake (Supplements & Food)

LOW RECOMMEN

DED HIGH Folate intake from food Folate intake from food Folate intake from food

Low Low

Recommended Low

Recommended High

Message No Message No Message No Message No Message No

L3.12.001

L3.12.002

L3.12.003

L3.12.004

L3.12.005

Any folate from supplements?

No Yes Message No Message No

L3.12.006

L3.12.007

Cholesterol Blood Levels Check Cholesterol levels

< 5 mmol 5 to 8 mmol >8 mmol Message

L3.18.012

Saturated Fat Intake Saturated Fat Intake

RECOMMENDED HIGH RECOMMENDED HIGH

Fibre Which food group contributes the most to saturated fat intake?

Fibre

Which food group contributes the most to saturated fat intake?

Low Recommended Low Recommended Message Message Message Message

L3.18.001 L3.18.001 Meat & Fish L3.18.002 L3.18.002 Meat & Fish

Message Message Dairy Message Message Dairy

L3.18.010 L3.18.011 L3.18.010 L3.18.011

Soup & Sauces Soup & Sauces

Sweets & Snacks Sweets & Snacks

Fats & Spreads Fats & Spreads

Potatoes, Rice & Pasta Potatoes, Rice & Pasta

Eggs Eggs

Food4Me Decision Trees

*Weight

*Cholesterol

*Omega-3

*Carotenoids

*Fat intake

*Unsaturated fat

*Salt intake

*Carbohydrates

*Protein

*Fibre

*Calcium

*Iron

*Folate

*Vitamin C

*Vitamin B12

*Thiamin

*Riboflavin

*Vitamin A

*Excercise

Decision trees service for nutritional advice

Quisper

API

Level 1 Level 2 Level 3

Study PDA: Personalized Dietary Advice for T2D

Quisper PDA services in the data portal

Food Intake

OPEN VitaLinq

FFQ

Genetics

GeneticLab

23andMe

FoodWiz

recipe of

the day

location

based

notification

(store?,

food

market?)

Recipes

retailers

Bloodwork

Vitas

SwissAnalysis

Theranos?

Robert Horlings - The Hyve

Barbara Koroušić -Jozef Stefan Institute (JSI)

Thomas Gundersen/Siv - Vitas

Otto Kness/Julia Nagel - Swiss Analysis

Iris de Hoogh

Wilrike Pasman

Ivana Bobeldijk

TNO Team:

Qualify:

Bedankt!

Dieticians!

Quisper 13

www.quisper.eu

www.qualify-fp7.eu

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This project has received funding from the European Union’s Seventh

Framework Programme for research, technological development and

demonstration under grant agreement no 613783.

Thank you