qp code 1401 reg. no.:………………… · 2019. 5. 14. · 3. gate control theory of pain...

QP Code 1401 Reg. No.:…………………

First Professional MBBS Degree Examinations - September 2011

PHYSIOLOGY - PAPER II

Time : 3 hrs Max marks : 50

• Answer all questions • Draw diagrams wherever necessary

Long essay (10) 1. A 50 yrs old male comes with the history of difficulty to walk. On examination

there is rigidity and resting tremors. His gait is abnormal. • What is your diagnosis. • How do you describe this rigidity and the resting tremor and explain

their physiological basis. • Name the parts of the brain involved . • Describe the important functional connections.

(1+3+2+4=10) Short Essay: (2x5=10) 2. Describe the endometrial changes during a normal menstrual cycle and its

hormonal regulation. 3. List any four functions of hypothalamus and explain any one

Write briefly on: (5x3=15) 4. Milk ejection reflex

5. Disynaptic reflex.

6. Mechanism of action of steroid hormones.

7. Decerebrate rigidity

8. Functions of vestibular apparatus Draw and label: (2x2½=5) 9. Cortico spinal tract

10. Auditory pathway Explain the physiological basis of the following: (5x2=10) 11. Exophthalmos is a clinical feature of thyroid dysfunction

12. Sertoli cells are important in spermatogenesis

13. Calcium plays a major role in skeletal muscle relaxation

14. Near point of vision recedes rapidly with advancing age

15. Parathyroidectomy leads to signs of neuromuscular hyperexitability

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Q.P.Code:104001 Reg. no.: …………………

First Professional MBBS Degree Examinations, August 2012

Physiology – Paper II

Time: 3 Hours Total Marks: 50 • Answer all questions• Draw diagrams wherever necessary

Long essay: (10)

1. A 30 years old female visits a clinic with the complains of weight gain, hoarseness ofvoice and irregular periods for the past 3 months. Her blood investigations showeddecrease in the T3 and T4 levels and increase in the TSH level·What is the clinical diagnosis·Describe the clinical features and their physiological basis·Discuss the steps involved in the synthesis of the hormone (2+5+3=10)

Short essays: (2x5=10) 2. Role of aldosterone in maintaining ECF sodium concentration3. Tests for ovulation

Answer briefly: (5x3=15)

4. Functions of CSF5. Cushing’s syndrome.6. Impedance matching7. Adaptation of receptors8. Functions of oestrogen

Draw and label: (2x2½=5)

9. Visual pathway

10. Stretch reflex and inverse stretch reflex

Explain the physiological basis of the following (5x2=10)

11. Lactation amenorrhea12. Maximal visual acuity occurs at the fovea centralis13. Fever during infection14. Broad based gait in cerebellar lesion15. Hearing is impaired during severe cold or sore throat

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Q.P. Code: 1401 Reg. no.: .....................

First Professional MBBS Degree Supplementary Examinations, March 2012

PHYSIOLOGY- PAPER II

Time: 3 Hours Total Marks: 50 • Answer all questions • Draw Diagrams wherever necessary

Long Essay: (10)

1. A patient developed carpopedal spasm after thyroid surgery. During examination, tapping over the facial nerve resulted in contraction of facial muscles

• What is the clinical diagnosis, mention the cause • What is the clinical sign elicited by tapping the facial nerve. • Name one another clinical sign elicited in this condition and how is it elicited • Name the hormones pertaining to the clinical condition. Describe the functions

of any one of them. • What treatment would you recommend for the patient (2+1+2+3+2=10)

Short Essay: (2x5=10)

2. Describe the role of hypothalamus in the regulation of food intake. 3. Connections and functions of basal ganglia.

Write briefly on 4. Tests for ovulation 5. Physiological actions of glucagon on carbohydrate metabolism

6. Hormones regulating spermatogenesis. 7. Describe the role of basilar membrane in frequency discrimination 8. Accommodation reflex

(5x3=15)

Draw and label (2x2½ =5)

9. Posterior column tracts 10. Mechanism of action of thyroid hormone on intracellular receptor

Explain the physiological basis of the following

11.Sensory homunculus 12.Reciprocal innervation 13. Contraceptive pills 14. Fluent aphasia 15.Glucocorticoids in stress

(5x2=10)

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Q.P. Code: 104001 Reg. no.: …………………


PHYSIOLOGY – Paper II

Time: 3 Hours Total Marks: 50 • Answer all questions

• Draw Diagrams wherever necessary

Long essay (10)

1. A 50 years old patient of hypertension suddenly developed weakness of right upper and

lower extremities and difficulty is speaking following a brief episode of loss of

consciousness. On examination motor tone of his right extremities was found to be

increased. Answer the following questions based on your knowledge in physiology :

• What would an examination of power and deep tendon reflexes of the patient reveal

• What would examination of the plantar reflex of the patient most likely reveal

• Explain the physiological basis of the findings of deep tendon reflexes in this patient

• What is the most likely clinical diagnosis of his condition (2+2+5+1=10)

Short essays (2x5 =10)

2. Metabolic effects of insulin

3. Denervation hypersensitivity

Answer briefly (5x3=15)

4. Accommodation reflex

5. Pituitary dwarfism

6. Parkinsonism

7. Features of cerebellar lesions

8. Ovarian cycle

Draw and label (2x2½=5)

9. Length-tension relationship in skeletal muscle

10. Wald’s visual cycle - flow chart


11. Patients with sensory ataxia lose balance on closing their eyes

12. Intra-uterine contraceptive devices prevent pregnancy

13. Diaphragmatic pain is felt at the tip of the shoulder

14. Patients of acromegaly may develop diabetes

15. Cardiac muscle cannot be tetanised

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Code: 104001 Reg. no.: …………………

First Professional MBBS Degree Supplementary Examinations, February 2013


Time: 3 Hours Total Marks: 50 • Answer all questions • Draw Diagrams wherever necessary

Long essay (10)

1. A 45 year old man has come to the hospital for remarkable changes in his appearance.

Physical examination: tongue is enlarged, hands and feet are enlarged with spade like

fingers and presence of hepatomegaly.

Fasting blood glucose is 150mg%. Fasting growth hormone level is 60ng/ml. Answer

the following questions based on your knowledge in physiology :

• Name the probable condition.

• Mention the normal fasting blood glucose value.

• Which is the hormone involved in this condition and what is the defect.

• Explain the actions of the hormone involved.

(1+1+2+6=10)

Short essays (2x5=10)

2. Describe the mechanism of action and regulation of aldosterone secretion.

3. Describe connections and functions of thalamus.


4. Stretch reflex.

5. Hypo function of thyroid gland.

6. Functions of sertoli cells.

7. Taste buds.

8. Waves in EEG


9. Visual pathway.

10. Lateral spinothalamic tract.


11. Trousseau’s sign.

12. Macular sparing.

13. Contraceptive pills.

14. Pain in the arm during cardiac angina.

15. Left internal capsule lesion produces right hemiplegia.

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Q.P. Code: 104001 Reg. no.: …………………

First Professional MBBS Degree Supplementary Examinations, February 2014




Long essay (10)

1. A 70 years old hypertensive male has come to the hospital with complaints of inability to

use the right upper and lower limb. Physical examination revealed hypertonia + and

exaggerated deep tendon reflexes on the right side. Babinski’s sign was positive on the

right side. Answer the following questions based on your knowledge in physiology :

• Name the clinical condition

• Explain the physiological basis of the above findings

• Differentiate between upper and lower motor neuron lesion.

• Why Babinski’s sign is positive. (1+5+3+1=10)


2. Describe about spermatogenesis and the hormonal factors regulating it.

3. Name the nuclei of hypothalamus. Enumerate the functions of hypothalamus and

describe any one in detail.


4. Functions of growth hormone

5. Aphasia.

6. Functions of limbic system.

7. Functions of placenta.

8. Intra uterine contraceptive devices.


9. Functional areas of cerebral cortex.

10. Organ of corti.


11. Lumbar puncture is done at L2 - L3 level.

12. Dark adaptation.

13. Pain disappears by rubbing the affected area.

14. Body temperature is slightly elevated after ovulation15. Pigmentation is seen in Addison’s disease.

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Q.P. Code: 104001 Reg. no.: …………………





Long essay (10)

1. A 40 years old man came to the OPD with a gait characterized by raising his feet

unnecessarily high and bringing it down in a stamping manner (stamping gait). He also

stood with his feet wide apart and tended to fall to the right with the eyes closed. Answer


● Where is the lesion in this patient. ● Describe the neural tract involved in this patient

with the help of a diagram. ● What are the sensations carried by this tract ● What is

dissociated anesthesia (1+5+2+2=10)


2. Describe hormonal and endometrial changes during menstrual cycle.

3. Describe the auditory pathway. List the types of deafness with a note on audiometry


4. Sensory homunculus

5. Dark adaptation

6. Role of the cerebellum in motor control

7. Physiological actions of growth hormones

8. Steps of spermatogenesis and list the hormones involved.


9. Feedback regulation of thyroid hormone secretion

10. Cortricospinal tract


11. End plate potential

12. Clasp knife rigidity

13. Contraceptive pills

14. Excitation contraction coupling.

15. Pigmentation in Addison’s disease.

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Q.P. Code: 104001 Reg. no.: …………………

First Professional MBBS Degree Supplementary Examinations - February 2015




Long essay (10)

1. A 30 years female with features of increased weight, menstrual abnormalities, cold

intolerance. Answer the following questions based on your knowledge in physiology :

• Name the probable condition with its cause

• What are the physiological actions of hormone related to this condition

• Mention the tests for diagnosing this condition. (1+7+2=10)


2. Functions of cerebellum

3. Ovarian cycle


4. Brown-sequard syndrome.

5. Tetany

6. Functions of testosterone

7. Mention the stages of sleep

8. Differences between the actions of adrenaline and nor-adrenaline oncardiovascular system


9. Organ of corti

10. Pain pathway from origin to termination


11. Cochlear microphonics

12. Hypermetropia

13. Blood brain barrier

14. Female contraceptive pill15. Hypoglycemic action of insulin

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Q.P. Code: 104001 Reg. no.: …………………

First Professional MBBS Degree Examinations - August 2015




Long essay (10)

1. A 33 years old woman complained of weight gain. Round face, thinning of her limbs

and increased bruising of skin with discoloration on her prominent abdomen. Answer


• What is the probable endocrinological disorder

• Explain The Metabolic Actions Of The Hormone Involved• Mention the major manifestations and their physiological basis (1+4+5=10)


2. Excitation –contraction coupling.

3. Gate control theory of pain


4. Mode of action of peptide hormone

5. Brown-sequard syndrome

6. Functions of thalamus

7. Safe period

8. Adreno-genital syndrome


9. Taste pathway

10. Multipolar Neuron


11. Babinski’s sign in new born

12. Polyuria in diabetes mellitus

13. Phantom limb

14. Dark adaptation

15. Presbyopia

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Q.P. Code: 104001 Reg. no.: …………………

First Professional MBBS Degree Supplementary Examinations - February 2016




Long essay (10)

1. A young woman has puffy skin and hoarseness of voice. Her plasma TSH concentration

is low. Answer the following questions based on your knowledge in physiology :

• Explain the physiological basis of her symptoms

• Describe the mechanism of action of thyroid hormones

• Explain the regulation of its synthesis

• What are its effects on nervous system (2+2+2+4=10)


2. Describe connections and functions of thalamus

3. Ovarian changes during a normal menstrual cycle


4. Functions of middle ear

5. Absolute refractory period

6. Cyclic GMP as second messenger

7. Functions of parietal lobe of brain

8. Milk ejection reflex


9. Pathway of crude touch

10. Visual pathway


11. Chorea

12. Referred pain13. Aldosterone escape phenomenon

14. Puberty

15. Bitemporal hemianopia

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Q.P. Code: 104001 Reg. no.: …………………

First Professional MBBS Degree Examinations - August 2016




Long essay (10)

1. A 50 years old lady was suffering from excess of sleep and tiredness, loss ofappetite, hoarseness, of voice for the last six months. On examination, she had non- pitting edema, dry scaly skin and prolonged reflex time. Answer the following questionsbased on your knowledge in physiology :

• What is your clinical diagnosis.

• What will be the TSH, T3 and T4 levels.

• What is the cause of low BMR.

• How can you treat the subject.

• What will be her resting pulse rate• Explain the action of thyroxine on the three metabolisms and on CNS.

(1 + 1+ 1+ 1+ 1+ 5=10) Short essays (2x5=10)

2. Describe the formation, composition and functions of aqueous humour.

3. Draw the functional divisions of cerebellum. Explain the functions of these

divisions with referring to their connections.


4. Functions of middle ear.5. Neuromuscular junction in skeletal muscle6. Role of hypothalamus in temperature regulation.7. Physiological basis of pregnancy tests.8. Testosterone.


9. Corticospinal tracts from it’s orgin to termination

10. Sarcomere


11. Nystagmus is observed in vestibular diseases

12. A 50 years old lady finds difficulty in reading and doing close work.

13.Contraception by oral contraceptive pills14. Cyclic AMP acts as a second messenger

15. Abnormal plantar reflex in neurological diseases.

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Q.P. Code: 104001 Reg. no.: …………………

First Professional MBBS Degree Supplementary Examinations

February 2017




Long essay (10)

1. An elderly man was admitted to the hospital with complaints of intense central chest

pain with radiation to left arm. Answer the following questions based on your

knowledge in physiology:

• What is the cause of the pain in the left arm and explain its mechanism.

• Describe the pain pathway in detail.

• Mention gate control theory of pain sensation (3+5+2=10)


2. Effects of hypo secretion of growth hormone

3. Events during neuromuscular transmission of impulse in skeletal muscle


4. Reciprocal innervation.

5. Paradoxical sleep.

6. Milk ejection reflex.

7. Dark adaptation

8. Cerebellum in voluntary activity


9. Taste pathway

10. Feedback regulation of thyroid hormone secretion


11. Renshaw cell inhibition

12. Safe period

13. Sterility in undescended testis14. Neuromuscular hyper excitability in tetany

15. Masking in audition

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Q.P. Code: 104001 Reg. no.: …………………

First Professional MBBS Degree Examinations July 2017




Long essay (10)

1. A 50 years old person complaints of increased appetite, increased thirst and increased

frequency of urination. The blood glucose was found to be 180 mg/dl. Answer the

following questions based on your knowledge in physiology :

● What is your probable diagnosis.

● Which hormone is affected.

● What are the physiological effects of this hormone in the body

● Enumerate the other hormones involved in the regulation of blood glucose(1+1+7+1=10)


2. Describe the regulation of body temperature during hot climate.

3. Describe the regulation of secretion of cortisol and its physiological role


4. Action of ADH

5. Types of EEG wave forms

6. Near response in normal eye

7. Pituitary dwarfism

8. Role of hypothalamus in feeding behavior


9. Muscle spindle

10. Neuromuscular junction in skeletal muscle


11. Re-polarization phase of action potential

12. Cogwheel rigidity

13. Starling’s law of muscle contraction

14. Immunological test of pregnancy.

15. Milk ejection reflex.

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Q.P. Code: 104001 Reg. no.: …………………

First Professional MBBS Degree Supplementary Examinations January 2018


Time: 3 Hours Total Marks: 50 Answer all questions Draw Diagrams wherever necessary

Long essay (10)

1. A 65 years old woman was admitted to the hospital with the complaints of intention tremor in the left arm and missing the target when he attempted to do a work. On examination eye reveals nystagmus. Answer the following questions based on your knowledge in physiology:

What is the diagnosis. Mention the characteristic of knee jerk in this patient. What is dysdiadachokinesia. Describe the gait in this patient giving the physiological basis What happens when floculo-nodular lobe is damaged. (2+2+2+2+2)


2. Mechanism of synaptic transmission

3. Role of mineralocorticoids in salt and water balanceAnswer briefly (5x3=15)

4. Milk ejection reflex

5. Hyper secretion of growth hormone6. Supra spinal modulation of pain

7. Functions of middle ear

8. Castration before pubertyDraw and label (2x2½ =5)

9. Antero lateral system

10. Visual pathwayExplain the physiological basis of the following (5x2=10)

11. Referred pain12. Thalamic phantom limb

13. Administration of L dopa in Parkinson’s disease

14. Permissive action of glucocorticoids

15. Corpus luteum of menstruation and pregnancy

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qp code 1401 reg. no.:………………… · 2019. 5. 14. · 3. gate control theory of pain...

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