Primary Pyoderma gangrenosum

Abela C.B., et.al. Pyoderma gangrenosum. British Journal of Oral and Maxillofacial Surgery. SW17 0QT, UK. Department of Plastic and Reconstructive Surgery, St George’s Hospital, Blackshaw Road, Tooting, London SW17 0QT, UK. 3 November 2005

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? Patient still awaiting biopsy results

Abela C.B., et.al. Pyoderma gangrenosum. British Journal of Oral and Maxillofacial Surgery. SW17 0QT, UK. Department of Plastic and Reconstructive Surgery, St George’s Hospital, Blackshaw Road, Tooting, London SW17 0QT, UK. 3 November 2005Pyoderma gangrenosum: a review. A. Neil Crowson, Martin C. Mihm Jr., and Cynthia Magro, pp 98

Pyoderma gangrenosum: Classification and management. Frank C. Powell, FRCPI, W. P. Daniel Su, MD, Harold O. Perry, MD . Dublin, Ireland, and Rochester, Minnesota

*Mainly involves lower extremities

http://emedicine.medscape.com/article/1123821-overview

Pyoderma gangrenosum: a challenge to the rheumatologist. Luciano Ferreira Coelho, Francine Guilherme Correia, Fernanda Assis Ottoni, Flávia Patrícia Sena Teixeira Santos, Luciana Baptista Pereira, Cristina Costa Duarte Lanna

CrowsonAN,Magro C, MihmMCJr.Py odermagangrenosum: a review.JCutan Pathol 2003; 30: 97^107.#BlackwellMunksgaard 2003.

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classic ulcer is extensive, with infiltrated borders, erythematous-violaceous, undermined, with necrotic background and granulation tissue

NB: Ulcers may be single or multiple, are more frequent in lower limbs and may be found in any other part of the body. Almost 30% of the patients present previous trauma caused by a wound(pathergy). Polypoid or bullous forms may rarely occur.

Pyoderma gangrenosum: a challenge to the rheumatologist. Luciano Ferreira Coelho, Francine Guilherme Correia, Fernanda Assis Ottoni, Flávia Patrícia Sena Teixeira Santos, Luciana Baptista Pereira, Cristina Costa Duarte Lanna

Picture taken from medscape.com

• Skin biopsies of all forms of PG show a central zone of necrotizing suppurative inflammation.

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• And also a “Sweet-like” vascular reaction defined by peripheral neutrophilic component, usually without concomitant fibrinoid necrosis.

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