Poster Presentations P3 S641

P3-392 PROMOTING ALZHEIMER’S DISEASE AD

INFORMATION AND AWARENESS

Wainer Silva, Universidade Federal Fluminense University, Niteroi - RIO

DE JANEIRO, Brazil.

Background: Alzheimer’s Disease can be more devastating than death itself

for those affected and theirfamilies. However, AD information and education

on items like prevention, socialand behavioral conditions can alleviate family

and patient conditions. In developing areas, especially rural areas, this kind of

information is hard to acquire, and often completely unavailable. Methods:

This project is a joint effort among Federal Fluminense University professors

and researchers (physicians, nurses, AD specialists) and Niteroi Norte Rotary

Club members and community volunteers. After initial assessment of the

need for information and awareness through interviews, a carefully organized

program of activities, lectures and counseling on how to copewith AD is pre-

sented to patients and families. Results: Results have shown patients and

their families trying to overcome their health condition. Further understand-

ing has led patients and families to replace their initial anger for promoting

valuable moments which make the patient feel safer and more comfortable.

Conclusions: Improved awareness and the access to readily available infor-

mation and counseling have shown that there can be a new way for facing the

reality of Alzheimer’s disease, providing them with a better quality of life.

P3-393 QUALITYASSESSMENT OFALZHEIMER’S

EVALUATION UNITS (AEUS): A CENSUS OF

ITALY’S LOMBARDY REGION UNITS

Carlotta Franchi, Istituto di Ricerche FarmacologicheMario Negri, Milan,

Italy.

Background:Very few studies have been conducted in Italy on the quality of

care offered to patients with dementia. Objective: To evaluate quality stan-

dards of Alzheimer Evaluation Units (AEUs) in the Lombardy region, in

northern Italy. Methods: A questionnaire was sent to 20 randomly selected

AEUs out of the 81 in the Lombardy region. The units were compared using

indicators related to structure, process and outcome. Results: The question-

nairewas completed and returned by 18AEUs. Quantitative and comparative

analysis showed that for each indicator group there were several differences

between the AEUs: 39% of EAUs did not reach half the maximum score for

structure indicators, 72% for process indicators and 22% for outcome indica-

tors. Grouping the scores for all three indicators, ten AEUs reached half the

maximum score, only one scored about 63%, and one did not reach 40%.

Conclusions:This system of indicators served to assess a representative sam-

ple of AEUs and, if used more extensively, could help set up measures to im-

prove quality, to ensure the best service for patients and caregivers.

P3-394 PROXY-RATED QUALITY OF LIFE IN

ALZHEIMER’S DISEASE: A 3-YEAR

LONGITUDINAL STUDY

Table

Language

disorder

lesion(MRI) hypometabolism

(PET)

Picture

naming

Picture

description

Case1 severe Putamen temporal lobe + -

wBroca posterior

frontal lobe

Case2 moderate Putamen temporal lobe ++ +

wBroca posterior

frontal lobe

Case3 mild Putamen temporal lobe + -

wWernicke anterior

frontal lobe

Asmus Vogel1, Suvosree Bhattacharya2, Frans Waldorff2,

Gunhild Waldemar2, 1Rigshospitalet, Copenhagen University Hospital,

Copenhagen, Denmark; 2Copenhagen University Hospital, Rigshospitalet,

Copenhagen, Denmark.

Background: Few studies have investigated Quality of Life (QoL) in a lon-

gitudinal perspective in patients with Alzheimer’s disease (AD), and the ma-

jority of patients in these studies had moderate or severe dementia. The aim

of this study was to investigate the change in proxy rated QoL in a large co-

hort of home living patients with AD over a period of 36 months. The asso-

ciation between change from baseline in QoL and changes in cognition,

ADL and neuropsychiatric symptoms was also investigated. Methods:

The sample consisted of 102 patients with mild AD and their primary care-

givers from the Danish Alzheimer’s Diseas Intervention Study. QoL was as-

sessed with the proxy-rated (primary caregivers) QOL-AD and the EQ-VAS

scale. Cornell Scale for Depression in dementia (CSDD), ADCS-ADL,

MMSE and NPI-Q were also applied. Evaluations were conducted at base-

line and thereafter at 12 and 36 months follow-up visits.Results: There was

a significant decline in mean QoL assessed by both the QOL-AD and the

EQ-VAS (p < 0.001). However, there were vast individual differences in

the QoL scores on both scales at 12 and 36 months follow-up. At the 12

months follow-up 48.3% of the sample had an improvement in their

QOL-AD score and on EQ-VAS scale an improvement in QoL was for in

28.1% of the sample. On EQ-VAS 22.1% showed no change in QoL after

12 months. Mean change from baseline in QOL-AD scores showed signif-

icant correlations (p < 0.01) with change in CSDD, ADCS-ADL and

MMSE scores at 12 months and with ADCS-ADL only at 36 months (p

< 0.01). Mean change from baseline in EQ-VAS did not now significant cor-

relationswith change in the clinical variables.Conclusions:QoL is a subjec-

tive concept and may not be influenced by the degree of cognitive

dysfunction. Future studies should investigate the factors for individual var-

iations in order to understand the nature of change of QoL in AD. UsingQoL

as an efficacy parameter in intervention studies is questionable.

P3-395 THE QUR’AN AND MEMORYA (STUDY OF THE

EFFECT OF RELIGIOSITYAND MEMORIZING

QUR’AN AS A FACTOR ON MEMORY)

Reem Al-Attas, Secondary School in KSA, Jeddah, Saudi Arabia.

Background: Aim of the study: Find the relationship between religiosity

"memorizing Qur’an"and the sharp healthy memory. Hypothesis: Assuming

that the Quran is an influential factor on the strength of memory in two

ways; religiosity and spirituality, and on themental stimulation then themem-

ory of those whomemorized the Qur’an is stronger than those who didn’t and

their probability to have memory problems and disorders is less. Methods:

The study has been applied on 580 people from both genders aged from

20-40, half of them were religious who memorized the Qur’anand the other

half weren’t. The test used in the studywas a designed paper contained a ques-

tionnaire and two tests, the questionnaire asked normal questions about factor

that may affect on memory. And the two tests were TYM (test your memory)

translated into Arabic after taking the permission from the authors in Adden-

brooke’sHospital, Cambridge, UK. and the 10 words test designed by Dr.

Gary Small from his book (The memory Bible). The grades of the two test

were between A-F. Results: Using the Qui-Square test to compare between

the A result in both groups religious and non-religious all the result were sig-

nificant and the religious group hadmoreA grades in both tests.Conclusions:

From the data collected the hypothesis were proved.

P3-396 DIFFERENT EFFECTS OF MUSIC THERAPY ON

LANGUAGE FUNCTIONS IN VASCULAR

COGNITIVE IMPAIRMENTASSOCIATEDWITH

FRONTAL GLUCOSE HYPOMETABOLISM

Kyoko Akanuma1, Masayuki Satoh2, Kimihiro Tezuka1, Yuriko Kato1,

Masatoshi Itoh3, Kenichi Meguro1, 1Tohoku University Graduate School of

Medicine, Sendai, Japan; 2Department of Geriatric Behavioral Neurology,

Sendai, Japan; 3Sendai Medical Imaging Center, Sendai, Japan.

Background: Clinically we know that some aphasic patients can sing well

despite their severe speech disturbances. We herein reported three patients

with vascular dementia (VaD, ADDTC criteria) with different severity of

symptoms, who had improved their speech function, especially word find-

ing, after singing training. FDG-PETwas performed to examine the relation-

ship between glucose metabolism at baseline and the change in language