prof chun-sing lee
TRANSCRIPT
Chair Professor of Materials Chemistry Head of Director of
Editor-in-Chief of WeChat ID: CityU_CSLee;
Research areas: Nanomaterials for energy (batteries, supercapacitors, solar
cells, photocatalysis etc) & biomedical applications (imaging, drug delivery, cancer therapy)
Organic optoelectronics (OLEDs, OPV, memory)
Prof Chun-Sing LEE
Chemistry DepartmentCenter of Super-Diamond & Advanced Films
(COSDAF)Materials Today Energy
Scopus ID: 16464316100
ab initio predictions for
• Thermochemical and spectroscopic properties for
main-group compound and transition-metal
complexes
• Reaction mechanisms for catalytic reactions
involving
C-H activation
CO2 reduction
H2O oxidation and O2 generation
• Development of theoretical CCSD(T)/CBS
methods for accurate predictions.
Dr K C LauBSc (PolyU), M.Phil. (CUHK), Ph.D. (UC Davis)
Associate Professor, Department of Chemistry, City
University of Hong Kong
Interested student may directly contact Dr Lau by email:
Research highlights – Prof. Michael H. W. Lam (Department of Chemistry)
Smart stimuli-responsive materials
Specific peptide-crosslinked hydrogels with built-in signal amplification mechanisms for the detection of pathogenic bacteria in food and clinical samples.
Molecularly imprinted hydrogels with novel functionalized protein-based binders for the recognition and capturing of cancer cells.
Smart shape-memory hydrogels with genomic DNA-crosslinkers.
Polymer brushes with electroresponsive intermolecular charge-transfer properties for reflective displays.
Janus nanoplatelets for reflective displays.
pH-responsive organometallic polymers based on a molecular pivot-joint machinery.
pH responsive photonic colloidal crystalline beads for in vivo imagining applicationsdeveloped by Michael Lam’s group, CityU, HK SAR
Research Interests and Expertise:Two-dimensional nanomaterials; Phase engineering of nanomaterials (PEN); Amorphous nanomaterials; Controlled epitaxial growth of heterostructures; Clean energy; Catalysis; (opto-)electronic devices; Nano- and bio-sensors; Water remediation
Representative Publications:• Phase engineering of nanomaterials, Nat. Rev. Chem., 2020, 4, 243-256. • Heterophase fcc-2H-fcc gold nanorods, Nat. Commun., 2020, 11, 3293.• Self-gating in semiconductor electrocatalysis, Nat. Mater., 2019, 18, 1098-1104. • Discovery of unusual 4H-phase twinned Au nanokites, Nat. Commun., 2019, 10, 2881.• Epitaxial growth of hybrid nanostructures, Nat. Rev. Mater., 2018, 3, 17089. • Lithiation-induced amorphization of Pd3P2S8 for highly efficient hydrogen evolution, Nat. Catal., 2018, 1, 460-468.• High phase-purity 1T'-MoS2 and 1T'-MoSe2 crystals, Nat. Chem., 2018, 10, 638-643.• Crystal phase-based epitaxial growth of hybrid noble metal nanostructures on 4H/fcc Au nanowires, Nat. Chem., 2018, 10, 456-461. • Facile synthesis of gold nanomaterials with unusual crystal structures, Nat. Protoc., 2017, 12, 2367-2378. • Controlled growth of high-density CdS and CdSe nanorod arrays on selective facets of two-dimensional semiconductor nanoplates, Nat. Chem., 2016, 8, 470-475. • 2D semiconductors for transistors, Nat. Rev. Mater., 2016, 1, 16052.• Wet-chemical synthesis and applications of non-layer structured two-dimensional nanomaterials, Nat. Commun., 2015, 6, 7873. • Stabilization of 4H hexagonal phase in gold nanoribbons, Nat. Commun., 2015, 6, 7684. • Surface modification-induced phase transformation of hexagonal close-packed gold square sheets, Nat. Commun., 2015, 6, 6571.• Hierarchical Ni-Mo-S nanosheets on carbon fiber cloth: a flexible electrode for efficient hydrogen generation in neutral electrolyte, Sci. Adv., 2015, 1, e1500259• Solution-phase epitaxial growth of noble metal nanostructures on dispersible single-layer molybdenum disulfide nanosheets, Nat. Commun., 2013, 4, 1444.• The chemistry of ultra-thin transition metal dichalcogenide nanosheets, Nat. Chem., 2013, 5, 263-275. • A general method for the large-scale synthesis of uniform ultrathin metal sulphide nanocrystals, Nat. Commun., 2012, 3, 1177. • Synthesis of hexagonal close-packed gold nanostructures”, Nat. Commun., 2011, 2, 292.
Professor Hua ZHANG Herman Hu Chair Professor of Nanomaterials; E-mail: [email protected]: https://scholars.cityu.edu.hk/en/persons/hua-zhang(8f4e048e-884d-4f19-b2b4-ca4d3d53c515).htmlPublons: https://publons.com/researcher/1434653/hua-zhang/ORCID: http://orcid.org/0000-0001-9518-740XGoogle citation: https://scholar.google.com/citations?user=Cgo45S8AAAAJ&hl=en
Professor Kenneth M. Y. LeungChair Professor of Environmental Toxicology & Chemistry
Director of State Key Laboratory of Marine Pollution (SKLMP)
Website: https://www.aquatictox.com/Email: [email protected]
WeC
hat I
D
Suggested Research Areas for PhD Studies:• Global Monitoring of pharmaceuticals and
endocrine disruptors in estuaries• Environmental antibiotic resistomes• Toxicology and derivation of water quality
criteria for emerging chemicals of concern• Restoration of oyster reefs and mangroves • Eco-engineered, living, shorelines• Environmental DNA and its application
Attractions:• Well-equipped and well-
funded SKLMP• Overseas training/field-trip• Tackle real-world problems
to improve the environment
Prof. Leung won the Biwako Prize for Ecology, SETAC Fellow Award, and Outstanding Research Student Supervisor Award (HKU), and is a top 1% cited scholar in Ecology/Environmental Science.
Dynamic Helical Metallopolymers:
Prof. Michael CW Chan (CityU)
600 800Wavelength / nm
Weak Attractive Ligand–Polymer Interactions (WALPI):
CatalysisLuminescent Sensing New Concepts: Shape-Persistent Bimetallic Design
1. Phosphorogenic probes for biomolecules
Chemical Communications 2017, 53, 3299 – 3302.
(c) Iridium(III) dinitrophenyl ether complexes
Journal of Inorganic Biochemistry 2017, 177, 412 – 422.
C
C
N
N
IrN
N
NH
O
O
O
NO2
NO2
C
C
N
N
IrN
N
NH2
1a
M.W. = 1116 M.W. = 800
Biothiols
1b
Weakly emissivecomplexes
Strongly emissivecomplexes
NO2
NO2
SR
O
CO2
+
S2 S2
C
C
N
N
IrN
N
NH
O
O
O
NO2
NO2
C
C
N
N
IrN
N
NH2
1a
M.W. = 1116 M.W. = 800
Biothiols
1b
Weakly emissivecomplexes
Strongly emissivecomplexes
NO2
NO2
SR
O
CO2
+
S2 S2
N
N
Ir
N
C
C
N NH O
O
O
NO2
NO2
++
N
N
Ir
N
C
C
N NH2
++
Biothiols
(a) Iridium(III) phenylboronic acid complexes
N
N
Ir
N
C
C
N O NH
O
O NH
BOHHO
3
++
Chemistry – An Asian Journal 2017, 12, 1545 – 1556.
(b) Ruthenium(II) fructose complexes
European Journal of Inorganic Chemistry 2017, 5288 – 5294.
Ru CellMask Overlaid
NHO
OCl
O
OH
H
N
C
Ir
N
NN
N
N
C N
+
+
O
O
enzymatic ligation
N2
IEDDA reaction
BCN-C6-Cl
3
NHO
OO
O
OH
HO
N
C
Ir
N
N
N
C N
H
H
+
NHO
OO
O
O
O
highly emissive bioconjugate
GST
GST-HaloTag
HaloTagprotein
very weakly emissive
NHO
OCl
O
OH
H
N
C
Ir
N
NN
N
N
C N
+
+
O
O
enzymatic ligation
N2
IEDDA reaction
BCN-C6-Cl
3
NHO
OO
O
OH
HO
N
C
Ir
N
N
N
C N
H
H
+
NHO
OO
O
O
O
highly emissive bioconjugate
GST
GST-HaloTag
HaloTagprotein
very weakly emissive
(a) Iridium(III) nitrone complexes
(b) Iridium(III) tetrazine-pyridine complexes
2. Novel photocytotoxic agents
Angewandte Chemie International Edition 2016, 55, 1046 – 1049. 3. Membrane-staining probes
Chemical Communications 2016, 52, 4557 – 4560.
+++
N
N
Ir
N
C
C
N N
O-
N
N
Ru
N
N
N
N
O
NH O
HO
OH
OHOH
2+
Prof. Kenneth Lo
Hypoxia- and Xenobiotic-induced Endocrine Disruption and Obesogenicity in Fish(Dr. Richard Y C Kong)
A B C
My research group is interested in the search and elucidation of the functional roles of novel proteins/miRNAs/mechanisms/pathways that may be associated with
hypoxia- and xenobiotic-induced endocrine disruption in fish. Laboratory and/or field studies by our group have previously demonstrated that hypoxia and certain
endocrine disruptors impair testicular development, reduce sperm production/motility and deregulate various signaling pathways in male fish (Fig. A).
Importantly, we demonstrated that hypoxia-induced reproductive impairments and epigenetic changes in F0 males were transgenerationally transmitted to the F1
and F2 males (Fig. B). Retardation of gonadal development by hypoxia was also observed in the fish ovary. RNA-seq transcriptome profiling of hypoxic testes
and ovaries of the marine medaka (Oryzias melastigma) followed by Gene Ontology (GO), KEGG and Ingenuity Pathway (IPA) analysis revealed differential
expression of gender-specific signaling pathways in male and female marine medaka (Fig. C). The regulatory effect of hypoxia on medaka ovary included
activation of progesterone synthesis, activation of internal genitalia development, and inhibition of atresia of the reproductive tract. In contrast, the regulatory
effect of hypoxia on testis included modulation of signaling pathways related to cell growth and apoptosis such as G2/M DNA damage checkpoint regulation, p53
signaling and VEGF signaling. Additionally, based on recent evidence from our group, it is hypothesized that the activation or inhibition of specific hypoxia-
responsive miRNAs, directly targeting the expression of the androgen receptor (AR) or coregulators of AR signaling, represent an important pathway that controls
sexual differentiation and development in fish. Studies to verify this are currently underway in my lab. The possibility that certain endocrine-disrupting chemicals(EDCs) that are obesogenic may have a role in disrupting reproductive functions in fish is also an area that is being investigated in my lab.
Hybrid Organic EO Materials: Femtojoule Modulation, Broadband
RF and Terahertz Photonics, and Quantum Electro-Optics
(LUO Lab: http://www.cityu.edu.hk/chem/profile/drjdl.html)
n = n3r33E/2
r33 ‐2(2) /n4
NIR Laser
Modulated Laser Output
01001011 01001011Electrical Signal (data signal)
Organic Photonics: Materials Chemistry and Processing
Exab
ytes
per M
onth
Chi‐Kit Andy SiuComputational Chemistry
Physical Organic [email protected]
Free electron:The lightest possible catalyst
Atmospheric Chemistry and Reaction Mechanisms in Hydrated Cluster Models
Collaborator: MK Beyer, University of Innsbruck, Austria
Electron transfers with hydrated electron
Theoretical Studies of Gas‐Phase Ion Chemistry with Quantum Chemical Computations
in Collaboration with Experimental Research Groups in Mass Spectrometry
Structural Characterization & Reaction Mechanisms of Bio‐molecular Ions in the Gas Phase
Collaborator: Ivan K Chu, University of Hong Kong
[G•GW]+ [GGW
•]+
Intramolecular Charge/Electron
Transfers
Dr. Alex Chun-Yuen WONG ([email protected])
Research Focus:(1) Activation of Alkynes by Transition Metals(2) Design of Metal-Heterocyclic and Metallacyclic Complexes(3) Development of Novel Metallodrugs and Nanoscale Drug Delivery System
Dr. Guangyu [email protected] www.zhulab.com
Representative publications:Angew. Chem. Int. Ed. 2018, 57, 9098Angew. Chem. Int. Ed. 2018, 57, 3426Chem. Sci. 2017, 8, 6865Angew. Chem. Int. Ed. 2016, 55, 15564(VIP and cover)
J. Am. Chem. Soc. 2015, 137, 383Nat. Commun. 2014, 5, 4466Angew. Chem. Int. Ed. 2013, 52, 13419Angew. Chem. Int. Ed. 2013, 52, 2027
Synthesis, properties and applications of novel low-dimensional metal
and metal-based nanomaterials
Dr. Zhanxi FAN, Assistant Professor
Overview Synthesis Structure Catalysis
Representative Publications:
Nature Rev. Chem. 4, 243 (2020)
Nature Protoc. 12, 2367 (2017)
Nature Commun. 11, 3293 (2020)
Nature Commun. 6, 7684 (2015)
Nature Commun. 6, 6571 (2015)
Acc. Chem. Res. accepted (2020)
Acc. Chem. Res. 49, 2841 (2016)
Chem. Soc. Rev. 45, 63 (2016)
Adv. Energy Mater. 10, 2002019 (2020)
Chem. Sci. 6, 95 (2015)
J. Am. Chem. Soc. 142, 12760 (2020)
J. Am. Chem. Soc. 138, 1414 (2016)
J. Am. Chem. Soc. 137, 10910 (2015)
Angew. Chem. Int. Ed. 54, 5672 (2015)
Adv. Mater. 29, 1701331 (2017)
Contact Information:
E-mail: [email protected]
Phone: +852 - 3442 7817
Fax: +852 - 3442 0522
Website: https://fanlab-cityu.wixsite.com/group
Exploring the Chemistry and Biology of Nucleic Acids
Dr. Chun Kit KWOK ([email protected])
Kwok Lab (https://kitkwok.com)
Our Research Vision
Representative Publications:
Nat. Methods https://doi.org/10.1038/s41592-018-0121-0 (2018)
Cold Spring Harb. Prespect. Biol. 10, pii:a032284 (2018)
Trends Biotechnol. 35, 997–1013 (2017).
Nat. Methods 13, 841-844 (2016).
Angew. Chem. Int. Ed. 55, 8958-8961 (2016).
Trends Biochem. Sci. 40, 221-232 (2015)
Nat. Protoc. 10 1050-1066 (2015).
Angew. Chem. Int. Ed. 54, 6751-6754 (2015).
Nature. 505, 696-700 (2014)
Key Collaborators:
UK--University of Cambridge , University of Oxford, etc
US--Cornell University, University of California, Davis, etc
Asia--National University of Singapore, Tsinghua University, etc
Hong Kong--University of Hong Kong, Chinese University of Hong Kong, etc
Postdocs and PhDs needed for RNA biology work!!!
Combination is the key, we will be the best
Physics + Chemistry + …
二维材料、纳米材料的合成表征、缺陷工程、电子学和光电子学器件1. Synthesis of 2D materials, nanomaterials
2. Defects engineering of 2D materials, nanomaterials
3. Design electronic/optoelectronic devices by combining 2D
materials and other functional materials.
Yudai Matsuda
Natural Product Biosynthesis & Bioengineering:
Harnessing Nature’s Synthetic Potential to Create Novel Molecules
Research Projects:
1. Elucidation of the biosynthesis of complex
and bioactive natural products
2. Genomics-driven discovery and derivatization
of natural products
3. Generation and evolution of “unnatural”
natural product pathways
Visit: http://staffweb1.cityu.edu.hk/ymatsuda/
25
Heterogeneous catalysis is highly associated
with “surface atomic arrangement” and “local
coordination” of active site !
We can map catalyst’ surface and acquire all
information such as concentration and
chemical state of surface cation, anion,
hydroxyl group and oxygen vacancy…etc. for
the investigation of true active site !
NMR-assisted surface understanding for the design of
nanocatalyst with high activityDr. Yung-Kang Will Peng
Assistant Professor
Probe added
Ruquan Ye, Ph.D.
Assistant Professor
Department of Chemistry
City University of Hong Kong
Email: [email protected]
Web: www.ye-lab.com
Laser-assisted Materials
Manufacturing
Catalysts for Energy
Conversions
We synthesize functional materials:
1. Used laser to form porous
graphene and applied them in
broad fields
2. Developed active catalysts for
energy storages and releasing
Do not hesitate to contact me for
potential positions if interested!
Functional Materials Laboratory
Material Innovation and Interface Engineering for Photovoltaic
Device
Solvent Chemistry& Crystallography
PhotophysicsPerovskites Solar Energy
Chem. Mater., 2018, 30 , 1556
Adv. Mater. 2016, 28, 10786;
Interfacial Engineering Lead replacement for sustainable energy
Flexible Devices to Roll-to-Roll
Printing
Adv. Mater. 2018 30, 1703800;
Adv. Energy Mater. 2017 7, 160137
Energy Environ. Sci., 2015, 8, 1160