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PRODUCT PROSPECTUS Probiotics and Prebiotics

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Page 1: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

PRODUCT PROSPECTUS

Probiotics and Prebiotics

Page 2: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

PURITY | POTENCY | PERFORMANCE

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Page 3: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

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CT PROSPECTU

S | TABLE OF CO

NTEN

TS

PROBIOTICS AND PREBIOTICS

Table of ContentsThe Klaire Labs® Story 4-5

Section 1: Probiotics Reference Guide 6-7

Section 2: Probiotics Ther-Biotic® Complete 8Ther-Biotic® Children’s Chewable 9Ther-Biotic® for Infants Powder 10Ther-Biotic® Women’s Formula 11Ther-Biotic® Metabolic Formula 11Ther-Biotic® Senior Formula 12Ther-Biotic® Detoxification Support 12Ther-Biotic® Factor 1 13Ther-Biotic® Factor 6 13Target gb-X™ 14 Target b2™ 15LactoPrime™ Plus 15BioSpora™ 16ABx Support™ 17Saccharomyces Boulardii 17

Section 3: PrebioticsGalactomune® 18BiotaGen® 19

How to Purchase 19

Caution: If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your healthcare professional before using this product.Keep out of reach of children.

Page 4: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

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CT PROSPECTU

S | THE KLAIRE LABS STO

RY

According to all who knew her, Claire Farr was a tireless crusader, genuine humanitarian, and dynamic entrepreneur with a “commitment to excellence for the nutritionally aware.” In 1969, driven by a personal struggle with severe food allergies and environmental sensitivities, Claire Farr set out on a mission to formulate and manufacture the highest quality, hypoallergenic nutritional supplements possible. As many dedicated entrepreneurs do, Claire set up shop in her own home in Carlsbad, California and Klaire Labs was born.

In her quest to develop a line of nutraceuticals that sensitive individualscould reliably tolerate, Claire initially focused on single ingredient formulations.

Unlike most nutritional supplement manufacturers at the time, Claire purchased only pharmaceutical grade raw ingredients selected specifically for maximum purity and bioavailability. She avoided the use of fillers and synthetic ingredients, while focusing on natural and synergistic constituents. The medical community began to take notice.

By this time, demand was growing for environmental, nutrition-focused, and integrative medical practitioners. As such, Claire and her unique products gained the attention and respect of a number of prestigious complementary medicine proponents. Word of consistently reliable outcomes spread, allowing Claire’s home-based start-up to grow into a new manufacturing facility, expanding her capabilities to include bottling and custom formulations.

The Klaire Labs® Story

Ther-Biotic® The original hypoallergenic probiotic offering tailored formulations for more personalized performances.

Page 5: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

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S | THE KLAIRE LABS STO

RY

It was not until 1983 that Claire introduced her first probiotic, a product category that ultimately became her most successful. Klaire Labs’ Ther-Biotic® formulations remain a leading professional brand to this day.

In 2004, Klaire Labs was sold to ProThera,® Inc. ProThera, Inc. was in turn acquired by Soho Flordis International (SFI) in 2013. SFI’s philosophy to empower healthcare providers with better, natural options aligned quite naturally with that of Claire Farr. Having dedicated their lives’ work to similar goals, the SFI founders represented a renewed commitment to, and a tangible investment in, Claire’s founding principles.

In 2017, SFI USA (comprised of the three originating companies: ProThera, Inc., Klaire Labs, and Complementary Prescriptions) christened a new >75,000 square foot, state-of-the-art manufacturing facility, including expanded scientific and support resources, advanced quality tools, and modernized processes.

Although SFI has acquired several exceptionally discriminating, independent nutraceutical manufacturers across the globe in recent years, shared values are the common thread. In the spirit of honoring the past as we embrace the future, all products manufactured at SFI USA in Reno, Nevada are now unified under the Klaire Labs brand and guiding philosophy.

#1 Best Seller

Page 6: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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TICS REFERENCE GU

IDE

Probiotics Reference Guide

Ther-Biotic® Line Ther-Biotic® Line Target Line Antibiotic Support

TB Complete TB Children’s Chewable TB for Infants TB Women’s

FormulaTB Metabolic

SupportTB Senior Formula

TB Detoxification

SupportTB Factor 1 TB Factor 6 Target gb-X™ Target b2™ ABx Support™ S. Boulardii LactoPrime™ Plus BioSpora™

General UseComprehensive Gut Microbiota Support

GI, Immune, Oral Health Support

GI, Immune, Metabolic Support

GI, Genitourinary Support

GI, Metabolic Support

GI, Immune Support

Detoxification Protocol Support

GI, Immune, Genitourinary Support

GI, Intensive Gut Barrier Support

Gut-Brain Axis, Healthy Mood, GI Support

Breast Health, Lactation, Infant Immunity Support

Probiotic for Antibiotic Support

Probiotic for Antibiotic Support

GI Support, FODMAP Diet

GI, Immune Support

Suggested Age Range ≥ 2 years ≥ 2 years ≥ 6 months ≥ puberty ≥ puberty ≥ 60 years ≥ 18 years ≥ puberty ≥ puberty ≥ 1 year ≥ 1 year ≥ 1 year > 1 year ≥ 1 year ≥ 10 years

CFU 25B, 100B 25B 5B 25B 25B 25B 50B 20B 100B 5B 3B 10B 3B 25B 2B

Prebiotic Base Inulin Inulin Inulin Inulin Cellulose Inulin Cellulose Inulin Cellulose Inulin Cellulose Inulin Cellulose Cellulose Cellulose

Dose Form Capsules, Powder Chewable Tablet Powder Capsules Capsules Capsules Capsules Capsules Capsules Sachets (powder) Capsules Capsules Capsules Capsules Capsules

Storage Refrigerated Refrigerated Refrigerated Refrigerated Refrigerated Refrigerated Refrigerated Refrigerated Refrigerated Shelf Stable Shelf Stable Refrigerated Refrigerated Refrigerated Shelf Stable

Hypoallergenic Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Sourced from human breast milk Yes Yes Yes Soy and dairy free

B. animalis X

B. bifidum X X X X X X X X X X

B. breve X X X X X X X X

B. bulgaricus

B. infantis X X X X

B. lactis X X X X X X X

B. longum X X X X X X X X

L. acidophilus X X X X X X X

L. brevis X X X

L. bulgaricus X

L. casei X X X X X X X X

L. fermentum X

L. gasseri X X X X

L. paracasei X X X X X

L. plantarum X X X X X

L. rhamnosus X X X X X X X X X X X

L. salvarius X X X X X X

Lc. lactis X

S. boulardii X X

S. thermophilus X

B. coagulans X

B. subtilis X

Page 7: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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TICS REFERENCE GU

IDE

Ther-Biotic® Line Ther-Biotic® Line Target Line Antibiotic Support

TB Complete TB Children’s Chewable TB for Infants TB Women’s

FormulaTB Metabolic

SupportTB Senior Formula

TB Detoxification

SupportTB Factor 1 TB Factor 6 Target gb-X™ Target b2™ ABx Support™ S. Boulardii LactoPrime™ Plus BioSpora™

General UseComprehensive Gut Microbiota Support

GI, Immune, Oral Health Support

GI, Immune, Metabolic Support

GI, Genitourinary Support

GI, Metabolic Support

GI, Immune Support

Detoxification Protocol Support

GI, Immune, Genitourinary Support

GI, Intensive Gut Barrier Support

Gut-Brain Axis, Healthy Mood, GI Support

Breast Health, Lactation, Infant Immunity Support

Probiotic for Antibiotic Support

Probiotic for Antibiotic Support

GI Support, FODMAP Diet

GI, Immune Support

Suggested Age Range ≥ 2 years ≥ 2 years ≥ 6 months ≥ puberty ≥ puberty ≥ 60 years ≥ 18 years ≥ puberty ≥ puberty ≥ 1 year ≥ 1 year ≥ 1 year > 1 year ≥ 1 year ≥ 10 years

CFU 25B, 100B 25B 5B 25B 25B 25B 50B 20B 100B 5B 3B 10B 3B 25B 2B

Prebiotic Base Inulin Inulin Inulin Inulin Cellulose Inulin Cellulose Inulin Cellulose Inulin Cellulose Inulin Cellulose Cellulose Cellulose

Dose Form Capsules, Powder Chewable Tablet Powder Capsules Capsules Capsules Capsules Capsules Capsules Sachets (powder) Capsules Capsules Capsules Capsules Capsules

Storage Refrigerated Refrigerated Refrigerated Refrigerated Refrigerated Refrigerated Refrigerated Refrigerated Refrigerated Shelf Stable Shelf Stable Refrigerated Refrigerated Refrigerated Shelf Stable

Hypoallergenic Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes Sourced from human breast milk Yes Yes Yes Soy and dairy free

B. animalis X

B. bifidum X X X X X X X X X X

B. breve X X X X X X X X

B. bulgaricus

B. infantis X X X X

B. lactis X X X X X X X

B. longum X X X X X X X X

L. acidophilus X X X X X X X

L. brevis X X X

L. bulgaricus X

L. casei X X X X X X X X

L. fermentum X

L. gasseri X X X X

L. paracasei X X X X X

L. plantarum X X X X X

L. rhamnosus X X X X X X X X X X X

L. salvarius X X X X X X

Lc. lactis X

S. boulardii X X

S. thermophilus X

B. coagulans X

B. subtilis X

Page 8: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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Probiotics

Ther-Biotic® CompleteOur most comprehensive, maximum-support probiotic formulaTher-Biotic Complete is a robust, broad-spectrum, hypoallergenic blend of 12 probiotic species in a base of inulin. Designed to supply a complete component of synergistic and complementary species, each capsule provides 25 billion CFU and each 0.25 teaspoon (1 gram) provides 100 billion CFU protected by our proprietary InTactic® technology for maximum viability throughout the intestinal tract.

• Maximum probiotic support with colonizing and transient strains

• Clean and hypoallergenic for optimal results• Available in 25B CFU capsules or 100B CFU powder

PowderSUGGESTED USE: Adults: 1/4 teaspoon daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Other ingredients: None.

K-TCP 2.25 oz. (64 grams) powder

Supplement FactsServing Size 1/4 Teaspoon (Approx. 1 gram) • Servings Per Container 60

Amount Per 1/4 Teaspoon

Probiotic Blend (100 billion CFU) 1 g*in a base of inulin (derived from chicory root)and InTactic® proprietary polysaccharide complexLactobacillus rhamnosus 24.0 billion CFU*Bifidobacterium bifidum 20.0 billion CFU*Lactobacillus acidophilus 12.0 billion CFU*Lactobacillus casei 10.0 billion CFU*Lactobacillus plantarum 8.0 billion CFU*Lactobacillus salivarius 8.0 billion CFU*Bifidobacterium longum 4.0 billion CFU*Streptococcus thermophilus 4.0 billion CFU*Lactobacillus bulgaricus 4.0 billion CFU*Lactobacillus paracasei 2.0 billion CFU*Bifidobacterium lactis 2.0 billion CFU*Bifidobacterium breve 2.0 billion CFU*

*Daily Value not established.

CapsulesSUGGESTED USE: Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), InTactic® proprietary polysaccharide complex, and L-leucine.

V775-06 60 vegetarian capsulesV775-12 120 vegetarian capsules

Supplement FactsServing Size 1 Capsule

Amount Per Capsule

Probiotic Blend (25 billion CFU) 280 mg*in a base of inulin (derived from chicory root)Lactobacillus rhamnosus 6.0 billion CFU*Bifidobacterium bifidum 5.0 billion CFU*Lactobacillus acidophilus 3.0 billion CFU*Lactobacillus casei 2.5 billion CFU*Lactobacillus plantarum 2.0 billion CFU*Lactobacillus salivarius 2.0 billion CFU*Bifidobacterium longum 1.0 billion CFU*Streptococcus thermophilus 1.0 billion CFU*Lactobacillus bulgaricus 1.0 billion CFU*Lactobacillus paracasei 0.5 billion CFU*Bifidobacterium lactis 0.5 billion CFU*Bifidobacterium breve 0.5 billion CFU*

*Daily Value not established.

#1 Best Seller

Page 9: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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Ther-Biotic® Children’s ChewableHigh-CFU, multispecies chewable probioticTher-Biotic Children’s Chewable is a broad-spectrum, hypoallergenic probiotic supplement designed for children 2 years of age and older. Our 25 billion CFU formulation, in a base of inulin, contains 8 total Lactobacillus and Bifidobacterium species which have been intensively researched and clinically shown to support gastrointestinal health and immune function in children.† The pleasant natural flavor makes daily supplementation easy.

• Broad spectrum gastrointestinal and immune support†

• Potent daily 25B CFU probiotic blend for anyone preferring a chewable option• Sweet, natural flavor is ideal for children

SUGGESTED USE: For children 2 years of age and older: Chew 1 tablet daily preferably 30 to 60 minutes following a meal or as directed by a healthcare professional. Not recommended for children less than 2 years of age.

Other ingredients: Xylitol, natural cherry flavor, natural vanilla flavor, silicon dioxide, stearic acid, magnesium stearate, and natural licorice extract.

K-TCC 60 chewable tablets

Supplement FactsServing Size 1 Tablet

Amount Per Tablet

Probiotic Blend (25 billion CFU) 224 mg*in a base of inulin (derived from chicory root)Lactobacillus species 17 billion CFU*Lactobacillus rhamnosusLactobacillus caseiLactobacillus salivariusLactobacillus paracaseiBifidobacterium species 8 billion CFU*Bifidobacterium infantisBifidobacterium bifidumBifidobacterium longumBifidobacterium breve

*Daily Value not established.

Page 10: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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SUGGESTED USE: For children over 12 months: 1 scoop, once or twice daily. For infants 6 to 12 months: 1 scoop daily. Mix product in infant formula, milk, juice, or sprinkled on food such as yogurt, apple sauce or cereal, or as recommended by your healthcare professional. For breastfeeding mothers, product can be added to expressed milk, or small amounts at a time can be dispensed by placing on nipple or finger.

Other ingredients: None.

K-TIF 2.33 oz. (66 grams) powderCAUTION: DO NOT feed powder directly to infants or children. If the infant or child has a medical condition, taking prescription drugs, or under the age of 6 months, consult your healthcare professional before using this product. Keep out of reach of children.

Supplement FactsServing Size 1 Scoop (Approx. 0.5 gram) • Servings Per Container 120

Amount Per Sccop % Daily Value

Proprietary Probiotic Blend (5 billion CFU) 500 mgLactobacillus species 2.5 billion CFU 150 mg

in a base of inulin (derived from chicory root)Lactobacillus rhamnosus *Lactobacillus casei *Lactobacillus paracasei *Lactobacillus gasseri *Lactobacillus salivarius *

Bifidobacterium species 2.5 billion CFU 350 mgin a base of inulin (derived from chicory root)Bifidobacterium infantis *Bifidobacterium bifidum *Bifidobacterium longum *Bifidobacterium breve *Bifidobacterium lactis *

*Daily Value not established.

Ther-Biotic® for Infants PowderA multispecies probiotic formula to meet the special needs of infantsTher-Biotic for Infants and children is a 10-species probiotic blend, in a base of inulin, designed to safely meet the metabolic, intestinal, and immune support needs of infants and young children.† This formula supports a normal infant microbiota that can be easily disrupted by cesarean section delivery, formula feedings, medications, environmental exposures, or maternal diet.† Each scoop (0.5 gram) provides 5 billion CFU. Safe gastrointestinal, metabolic, and immune support.†

• Developed specifically for infants’ and young childrens’ developmental needs• Clean and hypoallergenic for optimal results• Available in 5B CFU powder that can be mixed with breast milk, formula, or food

Page 11: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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Ther-Biotic® Women’s FormulaSupports genitourinary microbiota health†

Ther-Biotic Women’s Formula is a hypoallergenic blend of 10 species specifically designed to support a woman’s genitourinary system.† Lactobacilli modulate the mucosal immune response to undesirable microorganisms, secrete biosurfactants to block their adherence and disrupt biofilm formation, and produce lactic acid to promote a healthy vaginal pH.† Each capsule provides 25 billion CFU protected by our proprietary InTactic® technology for maximum viability.

• Concentrated probiotic support for women• Clean, hypoallergenic formula• Available in 25B CFU capsules

SUGGESTED USE: Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), InTactic® proprietary polysaccharide complex, and L-leucine.

K-TWF 60 vegetarian capsules

Supplement FactsServing Size 1 Capsule

Amount Per Capsule

Probiotic Blend (25 billion CFU) 300 mg*in a base of inulin (derived from chicory root)Lactobacillus species 20 billion CFU*Lactobacillus acidophilusLactobacillus brevisLactobacillus rhamnosusLactobacillus gasseriLactobacillus caseiLactobacillus salivariusLactobacillus plantarumBifidobacterium species 5 billion CFU*Bifidobacterium bifidumBifidobacterium breveBifidobacterium longum

*Daily Value not established.

Ther-Biotic® Metabolic FormulaMultispecies probiotic supports healthy weight and energy metabolism†

Ther-Biotic Metabolic Formula is a blend of 7 select probiotic species, in a base of cellulose, designed to increase intestinal diversity and support healthy metabolism and weight management. Each capsule provides 25 billion CFU.†

• Supports healthy energy homeostasis and glucose metabolism†

• Clean, hypoallergenic, and FODMAPS compliant• Available in 25B CFU capsules

Other ingredients: Cellulose and vegetarian capsule (hydroxypropyl methylcellulose, water).

K-MBS 60 vegetarian capsules

Supplement FactsServing Size 1 Capsule

Amount Per Capsule

Probiotic Blend (25 billion CFU) 113 mg*Lactobacillus acidophilusLactobacillus plantarumLactobacillus rhamnosusBifidobacterium lactisLactobacillus gasseriBifidobacterium breveBifidobacterium longum

*Daily Value not established.

SUGGESTED USE: Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Page 12: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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Ther-Biotic® Senior Formula Supports a healthy gut microbiota in aging individuals†

Ther-Biotic Senior Formula is a synergistic blend of 10 probiotic species, in a base of inulin, designed to support a balanced and diverse microbiota, and normal gastrointestinal and immune function for individuals over 60 years of age.† Each capsule provides 25 billion CFU protected by our proprietary InTactic® technology for maximum viability throughout the intestinal tract.

• Maximum probiotic support for individuals over 60†

• Clean and hypoallergenic for optimal results• Available in 25B CFU capsules

SUGGESTED USE: Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), InTactic® proprietary polysaccharide complex, and L-leucine.

K-TSR 60 vegetarian capsules

Supplement FactsServing Size 1 Capsule

Amount Per Capsule

Probiotic Blend (25 billion CFU) 300 mg*in a base of inulin (derived from chicory root)Bifidobacterium species 18 billion CFU*Bifidobacterium infantisBifidobacterium longumBifidobacterium breveBifidobacterium bifidumBifidobacterium lactisLactobacillus species 7 billion CFU*Lactobacillus acidophilusLactobacillus rhamnosusLactobacillus gasseriLactobacillus caseiLactobacillus plantarum

*Daily Value not established.

Ther-Biotic® Detoxification Support High-strength, 50 billion CFUTher-Biotic Detoxification Support is a concentrated 3-species blend specifically designed to complement detoxification protocols.† Selected species support endotoxin digestion and toxin uptake reduction through tight junction intestinal barrier support.† Each capsule provides 50 billion CFU protected by our proprietary InTactic® technology for maximum viability throughout the intestinal tract.

• Potent, probiotic detoxification support• Clean, hypoallergenic, and FODMAPS-compliant• Available in 50B CFU capsules

SUGGESTED USE: Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), InTactic® proprietary polysaccharide complex, and L-leucine.

V770-06 60 vegetarian capsules

Supplement FactsServing Size 1 Capsule

Amount Per Capsule

Probiotic Blend (50 billion CFU) 265 mg*Lactobacillus rhamnosus 20 billion CFU*Lactobacillus casei 20 billion CFU*Bifidobacterium bifidum 10 billion CFU*

*Daily Value not established.

Page 13: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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Ther-Biotic® Factor 1Lactobacillus rhamnosus, 20 billion CFUTher-Biotic Factor 1 is a concentrated, 20 billion CFU Lactobacillus rhamnosus strain in an inulin base. An extensively researched species, L. rhamnosus has been recognized for robust L(+) lactic acid production and immune support as well as genitourinary health.† Each capsule provides 20 billion CFU protected by our proprietary InTactic® technology for maximum viability throughout the intestinal tract.

• Concentrated L. rhamnosus formulation• Clean and hypoallergenic for optimal results• Available in 20B CFU capsules

SUGGESTED USE: Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), InTactic® proprietary polysaccharide complex, and L-leucine.

V771-06 60 vegetarian capsules

Supplement FactsServing Size 1 Capsule

Amount Per Capsule

Probiotic Blend in a base of inulin (derived from chicory root) 220 mg*Lactobacillus rhamnosus 20 billion CFU*

*Daily Value not established.

Ther-Biotic® Factor 6Ultra-strength, 100 billion CFU formulaTher-Biotic Factor 6 is a high potency, hypoallergenic probiotic blend, in a cellulose base, designed for individuals at high risk for occasional diarrhea and compromised gut barrier function.† Each capsule provides 100 billion CFU protected by our proprietary InTactic® technology for maximum viability throughout the intestinal tract.

• High-potency gastrointestinal support†

• Clean, hypoallergenic, and FODMAPS-compliant• Available in 100B CFU capsules

SUGGESTED USE: Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), InTactic® proprietary polysaccharide complex, and L-leucine.

K-TF6 60 vegetarian capsules

Supplement FactsServing Size 1 Capsule

Amount Per Capsule

Probiotic Blend (100 billion CFU) in a base of cellulose 595 mg*Bifidobacterium longumLactobacillus acidophilusLactobacillus rhamnosusBifidobacterium bifidumBifidobacterium lactisLactobacillus paracasei

*Daily Value not established.

Page 14: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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Target gb-X™

A targeted probiotic blend clinically demonstrated to support mood†

Target gb-X is a probiotic supplement specifically designed to support positive mood by influencing the gut-brain axis. It is powered by Ecologic BARRIER, a 5 billion CFU blend of 9 probiotic strains, that has been clinically shown to decrease overall cognitive reactivity to sad mood, rumination, negative thinking, and aggressive thoughts.1 Heightened cognitive reactivity to sad mood is an established risk factor for more serious mood alterations in otherwise healthy individuals, and is therefore considered an important target for interventions.

• Powered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains• Protected by PROBIOACT ® Technology for optimal efficacy and shelf-stability• Hypoallergenic, non-GMO powder offered in convenient, single serving sachets

Supplement FactsServing Size 1 Sachet (Approx. 2 g) • Servings Per Container 30

Amount Per Sachet % Daily Value

Calories 5

Total Carbohydrate 2 g <1%**

Sodium 70 mg 3%Potassium (as potassium chloride) 35 mg <1%

Ecologic BARRIER Probiotic Blend 2 g(5 billion CFU)Lactobacillus casei W56 *Lactobacillus acidophilus W37 *Lactobacillus brevis W63 *Lactococcus lactis ssp. lactis W58 *Bifidobacterium animalis ssp. lactis W52 *Lactococcus lactis ssp. lactis W19 *Lactobacillus salivarius W24 *Bifidobacterium bifidum W23 *Bifidobacterium lactis W51 *

*Daily Value not established.**Percent Daily Values are based on a 2,000 calories diet.

SUGGESTED USE: Dissolve the contents of 1 sachet in approximately 3-4 oz. of lukewarm water or mix with a dairy product such as milk or yogurt. Gently stir before consuming. Take on an empty stomach in the morning, before bed, or as directed by a healthcare professional. Suitable for children from the age of 1 year. Caution: When antibiotics are used, wait 2-3 hours before using this product. If you are pregnant, nursing, have a medical condition, or taking prescription drugs, consult your healthcare professional before using this product. Keep out of the reach of children.

Other ingredients: Maize starch, maltodextrin, inulin, polydextrose, vegetable protein, magnesium sulfate, and manganese sulfate.

GBX 30 sachets

Target gb-X Formulation

Function L. casei W56

L. acidophilus W37

L. brevis W63

Lc. lactis W58

B. lactis W52

Lc. lactis W19

L. salivarius W24

B. bifidum W23

B. lactis W51

Epithelial barrier function strengthening† X X X X

Cytokine modulation† X X X X X

Mast cell integrity support† X X X X

Circulating lipopolysaccharide suppression†

X X X

Page 15: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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Target b2™ A targeted probiotic clinically demonstrated to support lactation comfort and infant immune health†

Target b2 with Hereditum Lc40 is a targeted probiotic designed to extend the benefits of breastfeeding and support overall infant immune health.† This strain of Lactobacillus fermentum (CECT5716) is clinically demonstrated to support breast health and resolve discomfort associated with mammary dysbiosis.2,3

As many as one third of lactating women experience significant discomfort resulting in premature cessation of breastfeeding. Studies have shown that lactic acid bacteria isolated from human milk may prevent and resolve lactation-associated mammary dysbiosis. The Target b2 strain was isolated from colonizing Lactobacillus in healthy breast milk and specifically selected for safety, antimicrobial and immunomodulary properties.

One capsule per day in the third trimester through cessation of breast feeding is recommended. For more intensive support, increase to one capsule three times per day or as recommended by the healthcare professional.

Other ingredients: Microcrystalline cellulose, silicon dioxide, vegetarian capsule (hydroxypropyl methylcellulose, water), maltodextrin, sucrose, calcium carbonate, and sodium ascorbate.

‡Hereditum® is a registered trademark of Biosearch, S.A., Spain.

CONTAINS MILK.

TB2 90 capsules

Supplement FactsServing Size 1 capsule

Amount Per Capsule

Lactobacillus fermentum 3 billion CFU 30 mg*CECT5716 (Hereditum®‡ Lc40)

*Daily Value not established.

Suggested use: 1 capsule, 1 to 3 times daily (3 to 9 billion CFU) or as directed by a healthcare professional.

LactoPrime™ Plus25 bilion CFU, multispecies formulaThis broad-spectrum, 12-strain blend of 7 Lactobacillus and 5 Bifidobacterium species is provided in a base of purified plant cellulose. This formula is free of inulin and other prebiotics and polysaccharides making it suitable for those who have dietary restrictions such as a FODMAP diet.

SUGGESTED USE: Adults: 1 capsule daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water) and L-leucine.

K-LPP 60 vegetarian capsules

Supplement FactsServing Size 1 Capsule

Amount Per Capsule

Probiotic Blend (25 billion CFU) in a base of cellulose 240 mg*Lactobacillus species 19 billion CFU*Lactobacillus rhamnosusLactobacillus acidophilusLactobacillus brevisLactobacillus caseiLactobacillus plantarumLactobacillus salivariusLactobacillus paracaseiBifidobacterium species 6 billion CFU*Bifidobacterium bifidumBifidobacterium infantisBifidobacterium longumBifidobacterium lactisBifidobacterium breve

*Daily Value not established.

Page 16: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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BioSpora™ A combination of two spore-forming probiotics BioSpora is a powerful blend of genetically certified Bacillus coagulans and B. subtilis species formulated to provide unique probiotic support of healthy gastrointestinal and immune function.† Spore-forming bacilli have often been referred to as soil-based microorganisms because of their ubiquitous presence in the earth. Although found in the human GI tract, spore-forming bacilli have long been considered incidental, transient bacteria. However, research shows that Bacillus species are present in the GI tract in numbers higher than can be explained by ingestion alone. Germination of Bacillus spores within the human small intestine and transient colonization is now thought to be part of the normal life cycle of human-associated Bacillus species providing specific stimuli for healthy GI and immune system development and function. Each capsule of BioSpora supplies a total of 2 billion CFU of B. coagulans and B. subtilis spores positively identified through independent 16S ribosomal RNA gene sequencing. The spores are resistant to extremes of heat, ultraviolet radiation, solvents, hydrogen peroxide, and enzymes. The spores withstand stomach acid and germinate in the small intestine within 6 hours of ingestion. Ingested B. coagulans and B. subtilis reside in the human GI tract for up to 7 days following consumption. BioSpora is recommended for enhanced support of normal GI and immune function.† It is certified free of casein, gluten, and soy. BioSpora does not require refrigeration.

Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water) and coconut oil powder.

K-BSP-12 120 vegetarian capsules

Supplement FactsServing Size 1 Capsule

Amount Per Capsule

Probiotic Blend (2 billion CFU) in a base of cellulose 260 mg*Bacillus coagulansBacillus subtilis

*Daily Value not established.

SUGGESTED USE: 1 capsule daily or as directed by a healthcare professional.

Page 17: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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ABx Support™ Powerful intestinal microbiota support during antibiotic therapy†

ABx Support is a carefully researched blend of the non-pathogenic yeast Saccharomyces boulardii with Lactobacillus rhamnosus, Bifidobacterium bifidum, and Bifidobacterium breve, probiotic microorganisms which have been shown in numerous controlled clinical trials to reinforce the commensal gut bacteria during antibiotic therapy.†

S. boulardii has versatile gastrointestinal effects. It stimulates intestinal brush border enzymes to maintain normal digestive functions.† It stimulates D-glucose and sodium absorption and produces short-chain fatty acids that nourish colon mucosa. Additonally, the ABx species enhance innate and acquired immunity, decrease T cell proliferation, induce helper (CD4+) T cell hypo-responsiveness, increase phagocytic activity in peripheral white blood cells and killing activity in natural killer cells, and support inflammation metabolism.†

This hypoallergenic formulation is provided in vegetarian capsules in bottles of 28 capsules, a convenient 14-day supply for concurrent use during antibiotic therapy, or larger bottles of 60 capsules to continue to support GI after antibiotic therapy.

SUGGESTED USE: Adults: 1 capsule twice daily with food or as directed by a healthcare professional. Children: As directed by a healthcare professional.

Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water).

K-ABX 28 vegetarian capsulesK-ABX-60 60 vegetarian capsules

Supplement FactsServing Size 1 Capsule

Amount Per Capsule

Probiotic Blend (10 billion CFU) 400 mg*in a base of inulin (derived from chicory root)Saccharomyces boulardii 5.0 billion CFU* Lactobacillus rhamnosus 2.5 billion CFU* Bifidobacterium bifidum 1.25 billion CFU* Bifidobacterium breve 1.25 billion CFU*

*Daily Value not established.

Saccharomyces Boulardii A powerful transient yeast probioticSaccharomyces boulardii is a nonpathogenic, transient yeast long used to support normal bowel transit time.† It is a hardy, acid-resistant, temperature tolerant microorganism that is not affected by antibacterial agents. S. boulardii is genetically and functionally distinct from brewer’s yeast (S. cerevisiae) and different from pathogenic Candida species.

SUGGESTED USE: 1 capsule twice daily with meals or as directed by a healthcare professional.

Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water) and L-leucine.

V776-06 60 vegetarian capsulesV776-12 120 vegetarian capsules

Supplement FactsServing Size 1 Capsule

Amount Per Capsule

Probiotic Blend in a base of cellulose 320 mg*Saccharomyces boulardii 3 billion CFU*

*Daily Value not established.

Page 18: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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Prebiotics

Galactomune®

Targeted prebiotic support for healthy intestinal microflora†

Galactomune provides a synergistic blend of two well-researched prebiotic fibers, galactooligosaccharides (GOS) and beta-glucan, formulated to nourish and support growth of beneficial Bifidobacterium and Lactobacillus species. The microbiota is comprised of hundreds of bacterial species, that support a wide variety of body functions from digestion and metabolism to immunity and mental health. Prebiotics such as GOS and beta-glucans contribute to soluble fiber intake, essential to commensal organism health and normal bowel function.

The galactooligosaccharides (derived from lactose) and betaglucans (derived from Saccharomyces cerevisiae) in Galactomune powder and capsules are extensively purified.

• Support for healthy intestinal microflora †

• Clean and hypoallergenic formula• Supports probiotic supplementation

PowderSUGGESTED USE: 1 scoop, 1 to 2 times daily with food or as directed by a healthcare practitioner. Mix powder in cold, warm, or hot foods or beverages as desired.

Supplement FactsServing Size 1 Scoop (Approx. 1 teaspoon or 5 grams) • Servings Per Container 30

Amount Per Scoop % Daily Value

Calories 5Total Carbohydrate 5 g 2%**

Dietary Fiber 4 g 16%**

Galactomune® Prebiotic Blend 5 g Galactooligosaccharides *Beta-Glucan (purified from Saccharomyces cerevisiae) *

*Daily Value not established. **Percent Daily Values are based on a 2,000 calorie diet.

Other ingredients: None.

CONTAINS MILK AND FISH (BONITO).

K-GAL 5.3 oz. (150 grams) powder WARNING: This product can expose you to chemicals including lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food

CapsulesSUGGESTED USE: 1 capsule twice daily with food or as directed by a healthcare professional.

Supplement FactsServing Size 1 Capsule

Amount Per Capsule

Galactomune® Prebiotic Blend 550 mg*GalactooligosaccharidesBeta-Glucan (purified from Saccharomyces cerevisiae)

*Daily Value not established.

Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water), L-leucine, and cellulose.

CONTAINS MILK AND FISH (BONITO).

K-GALC 60 vegetarian capsulesK-GALC1 120 vegetarian capsules

Prebiotic fiber goes through the small intestine undigested and is fermented by gut bacteria when it reaches the colon. This fermentation process by gut bacteria feeds beneficial

bacteria colonies (including probiotic bacteria) and helps to increase the number of desirable bacteria in our digestive systems that support health.

Page 19: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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BiotaGen®

A comprehensive prebiotic formulaBiotaGen is a combination of prebiotic fibers formulated with a unique blend of inulin, arabinogalactan, and beta-glucan. Human digestive enzymes are not able to break down most fibers found in complex carbohydrates and plant polysaccharides. Instead, these fibers act as prebiotics that nourish the gut microbiota. Through the fermentation process, commensal organisms use these fibers to generate the short-chain fatty acids (SCFAs) instrumental in colon cell nourishment, intestinal barrier integrity, and other systemic functions.† BiotaGen also contains the prebiotic arabinogalactan, derived from Larix occidentalis. Arabinogalactan may help aid the immune system by supporting normal macrophage activity and healthy immune cell function within the body.† Beta-glucan, isolated from Saccharomyces cerevisiae, also supports healthy immune system cells, including monocytes, macrophages, and natural killer cells.†

• Three prebiotic fibers in one formula• Available in capsule and powder format• Supports health of gut microbiota species and host immune system

CapsulesSUGGESTED USE: 4 capsules, 1 to 2 times daily or as directed by a healthcare professional.

Supplement FactsServing Size 4 Capsules

Amount Per 4 Capsules % Daily Value

Calories 5Total Carbohydrate 3 g 1%**

Dietary Fiber 2 g 7%**

BiotaGen® Prebiotic Blend 3 g *Inulin (derived from chicory root)Beta-Glucan (purified from Saccharomyces cerevisiae)Arabinogalactan (Larix laricina), (larch tree wood)

(water-soluble polysaccharide extract)

*Daily Value not established. **Percent Daily Values are based on a 2,000 calorie diet.

Other ingredients: Vegetarian capsule (hydroxypropyl methylcellulose, water) and L-leucine.

K-BTGC 120 vegetarian capsules

WARNING: This product can expose you to chemicals including lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food

PowderSUGGESTED USE: 1 scoop, 1 to 2 times daily. Mix with water, juice or food, or as directed by a healthcare professional.

Supplement FactsServing Size 1 Scoop (Approx. 1 teaspoon or 5 grams) • Servings Per Container 30

Amount Per Scoop % Daily Value

Calories 5Total Carbohydrate 5 g 2%**

Dietary Fiber 4 g 16%**

BiotaGen® Prebiotic Blend 5 g *Inulin (derived from chicory root)Beta-Glucan (purified from Saccharomyces cerevisiae)Arabinogalactan (Larix laricina), (larch tree wood)

(water-soluble polysaccharide extract)

*Daily Value not established. **Percent Daily Values are based on a 2,000 calorie diet.

Other ingredients: None.

K-BTG 5.3 oz. (150 grams) powder

† These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Contact us and order today klaire.com | 888 488 2488Available through licensed healthcare professionals.

Page 20: PRODUCT PROSPECTUS Probiotics and Prebiotics...† The pleasant natural flavor makes daily supplementation easy. • Broad spectrum gastrointestinal and immune support† • Potent

1. Steenbergen L, et al. A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactvity to sad mood. Brain Behav Immun. 2015 Aug;48:258-64.

2. Jiménez E, et al. Oral administration of Lactobacillus strains isolated from breast milk as an alternative for treatment of infectious mastitis during lactation. Appl Environ Microbiol. 2008,74(15):4650-4655.

3. Arroyo R, et al. Treatment of infectious mastitis during lactation: antibiotics versus oral administration of Lactobacilli isolated from breast milk. Clin Infect Dis. 2010;50(12):1551-1558.

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