principles of invasive hemodynamic monitoring xxx

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    PRINCIPLES OF INVASIVEHEMODYNAMIC

    MONITORINGMarelno Zakanito

    030.07.153

    Pembimbing:dr. Dean Wahjudy ,Sp.OG

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    There are four basic parameters necessary to describe

    comprehensively the hemodynamic status of any

    pregnant patient:

    preload,

    afterload,

    contractility,

    and heart rate.

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    Preload

    Preload refers to the volume of blood contained within a

    ventricle at cardiac end-diastole.

    Preload is determined by blood return to the ventricle and

    thus is directly related to intravascular volume.

    If increased amounts of blood enter the heart during

    diastole. The normal heart will respond with increased

    velocity of contraction and thus increased stroke volume.

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    Afterload

    Afterload represents the downstream resistance offered to

    each ventricle during cardiac systole. Cardiac output is

    inversely related to afterload (figure 4-1).

    Clinically, afterload is assessed as systemic vascular

    resistance, a derived parameter based upon blood

    pressure, central venous pressure, and cardiac output.

    Right ventricular afterload is represented by pulmonary

    vascular resistance, and left ventricular afterload by

    systemic vascular resistance.

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    Figure 4-1

    Cardiac output (CO)

    versus mean arterial

    pressure (MAP).

    Increasing systemicvascular resistance

    (SVR) is demonstrated

    by isometric lines.

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    Figure 4-2 ventricular

    end-diastolic volume

    versus ventricular

    performance. Increased.

    Normal and impairedcontractility are

    demonstrated.

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    Contractility

    Contractility refers to the intrinsic contractile property of

    the myocardium. While alterations in preload affect the

    movement of stroke volume along a given Starling curve,

    alterations in contractility affect the Starling curve upon

    which the cardiac output operates (figure 4-2)

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    Contractility may be altered by various disease states or

    by pharmacologic agents that have positive or negative

    inotropic effects. One of the most useful measures of

    contractility is stroke work index, a derived parameter

    (figure 4-3)

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    Heart Rate

    Cardiac output is also directly affected by heart rate,

    independent of either Starlings forces or alterations in

    contractility. In the normal heart, cardiac output generally

    increases with normal heart rate to the limits of

    physiologic tachycardia.

    However, at extremely rapid rates, ventricular filling and

    end-diastolic volume will be diminished because of

    inadequate diastolic filling time; under these

    circumstances, cardiac output will decrease.

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    Figure4-3

    Pulmonary capillary

    wedge pressure

    (PCWP) versus left

    ventricular stroke workindex (LVSWI): Normal

    relationship represented

    by shaded area.

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    Clinical Assessment

    In practice, blood pressure, pulse, and body surface area

    are measured in standard clinical fashion. Central venous

    and pulmonary capillary wedge pressure are measured

    from the proximal and distal ports of pulmonary artery

    catheter. Cardiac output is measured using thermodilution technique associated with the pulmonary artery

    catheter and a cardiac output computer. Once these

    parameters have been obtained clinically, derived

    parameters such as systemic and pulmonary vascularresistance and left ventricular stroke work index may be

    calculated in putting together the complete hemodynamic

    picture of the patient.

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    Blood Pressure

    True interarterial pressures obtained by direct arterial line

    measurements are more accurate than cuff pressures. As

    a rule, interarterial catheters result in pressure from 4-8

    mm higher than corresponding cuff pressures. This

    principle, however, is generally valid only in normalpatients; in certain subsets of critically ill patients,

    interarterial pressure may be up to 30 mmHg higher than

    those obtained from a peripheral cuff.

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    Mixed Venous Oxygen Saturation

    (SV02) Monitoring SV02 may be assessed either periodically by direct

    sampling from the distal port of pulmonary artery catheter

    or continuous use of a pulmonary artery catheter

    equipped with fiberoptic oximetry sensor. SVo2is

    determined by four parameters: cardiac output.

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    Pulse Oximetry

    Pulse oximetry is based upon the principle of differential lighttransmittance by oxygenated and nonoxygenated hemoglobinand depends upon the use of two light-emitting diode(LED)sources; one red (660 nanometers) and one infrared (940nanometers). Using a spectrophotometric device and an

    associated microprocessor, pulse oximeters will evaluate 02saturation with each pulse. In critically ill pregnant patients withtenuous physiologic oxygenation, pulse oximetry is aninvaluable technique. The use of this technique often allows theclinician to avoid multiple arterial blood gases and, at the same

    time, provides a continuous rather than intermittent method ofpatient evaluation. This technique should be a routine part ofthe management of any critically ill patient whose oxygenstatus is or may be compromised. Recent investigations intothe use of fetal pulse oximetry may also prove clinically fruitful.