practice teaching course in head and neck cancer management · practice teaching course in head and...
TRANSCRIPT
Practice teaching course in head and neckcancer management4-6 October 2017 - Buenos Aires, Argentina
PRACTICE TEACHING COURSE FINAL PROGRAMME
OverviewSurgery, radiation, and chemotherapy remain the primary treatment modalities for patientsaffected by head and neck squamous cell carcinoma. major advances in this disease have beenmade in the development of newer technologies, such as in radiation therapy, whether byintensity-modulated radiation therapy (IMRT) or proton-beam therapy. There have also beensignificant advances in the surgical treatment of head and neck cancer and in reconstructivemethods, allowing our patients improvements in quality-of-life. Treatments are intensive, andthus are associated with significant acute and late toxicities. As treatments have become moreeffective, survivorship and long-term quality of life have gained particular relevance. Aim of thecourse is to provide an overview of current evidence and management, recent developments, andinsights into future directions for the management of head and neck squamous cell carcinoma.
Learning objectivesAfter attending this course participants will be able to: • Recognize rationale and benefits of working in a multidisciplinary team• Summarize current treatment options for head and neck squamous cell carcinoma• Critically review future trends in the management of and neck squamous cell carcinoma
Target audienceThis course is meant for specialists with an experience in the management of head and neckcancer patients, including surgical, medical and radiation oncologists.
ChairsRaúl Eduardo GiglioOncology unit for head and neck cancerHopital Ángel H. RoffoBuenos Aires, Argentina
Jordi GiraltRadiation Oncology unitVall d’Hebron University HospitalBarcelona, Spain
EXCEMED designed this programme in partnership with Prova Education.
4
Practice teaching course in head and neck cancermanagement
CME ProviderEXCEMED is a non profit foundation dedicated, since the last four decades, to the development ofhigh-quality medical education programmes all over the world.
EXCEMED adheres to the guidelines and standards of the European Accreditation Council forContinuing Medical Education (EACCME®) which states that continuing medical education mustbe balanced, independent, objective, and scientifically rigorous.
Continuing medical educationEXCEMED (www.excemed.org) is accredited by the European Accreditation Council forContinuing Medical Education (EACCME®) to provide the following CME activity for medicalspecialists. The EACCME® is an institution of the European Union of Medical Specialists (UEMS),www.uems.net
The CME “Practice teaching course in head and neck cancer management” held on 4-6 October2017 in Buenos Aires, Argentina, is designated for a maximum of 16 (sixteen) hours of EuropeanCME credits (ECMEC). Each medical specialist should claim only those credits that he/sheactually spent in the educational activity. EACCME® credits are recognized by the AmericanMedical Association (AMA) towards the Physician's Recognition Award (PRA). To convertEACCME® credit to AMA PRA category 1 credit, please contact the AMA.
EXCEMED adheres to the principles of the Good CME Practice group (gCMEp).
5
VenueThis live educational course takes place at:
Hopital Ángel H. Roffo Av. San Martín 5481Buenos Aires, Argentina
LanguageThe official language of this live educational course is English.
CME ProviderEXCEMED - Excellence in Medical Education
Programme Manager: Silvia CristofanelliT +39 06 420413 421 - F +39 06 420413 [email protected]
Medical Advisor: Cristina [email protected]
For any logistic inquiry, please contact:Meridiano Congress InternationalSenior Project Manager: Federica RussettiT +39 06 88 595 209 - F +39 06 88595 [email protected]
6
7
FormatThis live educational educational event is allowing participants to express their own views andopinions through interactive workshops with clinical cases, panel discussions, real-time surveyswith voting system, questions cards and dedicated website.
Dedicated websiteAccess the dedicated website .............................. to:√ Xxx xxx√ Xxx xxx√ Xxx xxx√ Xxx xxx
Mobile applicationDownload the conference application “.............................”and enjoy easy access to:√ Xxx xxx√ Xxx xxx√ Xxx xxx√ Xxx xxx
Any question?You can pose your question by using the question card in your folder√ Xxx xxx√ Xxx xxx√ Xxx xxx
Faculty
Roque AdanChief Head and Neck Cancer SurgeryHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
Barbara BerensteinHead and Neck SurgeonHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
Nicolás BustosRadiologistHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
Juan Manuel CarreraMedical OncologistHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
Celeste DiazMedical OncologistHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
Emiliano GarayaldeHead and Neck SurgeonHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
Raúl Eduardo GiglioHead Medical OncologyHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
10
Jordi GiraltRadiation Oncology unitVall d’Hebron University HospitalBarcelona, Spain
Mauricio JacianskyHead and Neck SurgeonHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
Marcos David PereiraMedical and Radiation OncologistHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
Gonzalo ZeballosETN SpecialistHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
11
Legend:
L : Lecture : Sharing experience : Clinical case : Keynote lecture : Journal club
Wednesday, 4 October 2017
12.30 RegistrationWelcome Lunch
13.30 Opening and local welcome
13.40 L1: Oropharyngeal cancersR.E. Giglio
14.10 L2: Larynx and hypopharyngeal cancersM. Jaciansky, G. Zeballos
14.40 L3: Oral cavity cancersR. Adan
15.10 Coffee Break
15.30 L4: Rationale, definitions and benefits of working in a multidisciplinary teamM.D. Pereira
16.00 L5: General principles of radiologyN. Bustos
16.15 L6: General principles of surgeryE. Garayalde
16.30 L7: General principles of radiotherapyM.D. Pereira
16.45 L8: General principles of systemic therapiesJ.M. Carrera
17.00 Sharing experience session B. Berestein
17.30 End of the first day
HNSCC Overview Session I
Multidisciplinary cancer care in HNSCCSession II
14
15
08.00 MDT (multidisciplinary tumor board at Instituto Roffo)
09.00 Outpatient clinic
12.30 Lunch
13.30 L9: Current treatment options for locally advanced13.30 HNSCC (induction therapy, organ preservation, treatment combinations)
R.E. Giglio
14.15 L10: The future of personalised radiotherapy treatment for head and neck cancer J. Giralt
14.45 Coffee break
15.00 L11: Current treatment options for recurrent/metastatic HNSCC (first linetreatment, second line treatment, immunotherapies)J.M. Carrera
15.30 Clinical case discussionB.Berenstein - M. Jaciansky
16.30 End of the second day
Practical session Session III
HNSCC TreatmentSession IV
Thursday, 5 October 2017
Friday, 6 October 2017
08.30 Keynote lecture “Multidisciplinary management of head and neck cancer: First expertconsensus using Delphi methodology from the Spanish Society for Head andNeck Cancer”J. Giralt
09.10 Second opinion MDT (multidisciplinary tumor board at Instituto Roffo)R. Adan, J.M. Carrera, R.E. Giglio, M. Jaciansky, M.D. Pereira
12.30 Lunch
13.30 Clinical trials for HNSCC opened at Instituto RoffoR.E. Giglio
14.30 Journal clubC. Diaz
15.30 End of the live educational course
Practical Session Session V
16
Faculty disclosures
EXCEMED adheres to guidelines of the European Accreditation Council for Continuing MedicalEducation (EACCME®) and all other professional organizations, as applicable, which state thatprogrammes awarding continuing education credits must be balanced, independent, objective andscientifically rigorous. Investigative and other uses for pharmaceutical agents, medical devices andother products (other than those uses indicated in approved product labeling/package insert for theproduct) may be presented in the programme (which may reflect clinical experience, theprofessional literature or other clinical sources known to the presenter). We ask all presenters toprovide participants with information about relationships with pharmaceutical or medicalequipment companies that may have relevance to their lectures. This policy is not intended toexclude faculty who have relationships with such companies; it is only intended to informparticipants of any potential conflicts so that participants may form their own judgements, based onfull disclosure of the facts. Further, all opinions and recommendations presented during theprogramme and all programme-related materials neither imply an endorsement nor arecommendation on the part of EXCEMED. All presentations represent solely the independent viewsof the presenters/authors.
The following faculty provided information regarding significant commercial relationships and/ordiscussions of investigational or non-EMEA/FDA approved (off-label) uses of drugs:
Barbara Berenstein Declared no potential conflict of interest
Juan Manuel Carrera Declared no potential conflict of interest
Celeste Diaz Declared no potential conflict of interest
Jordi Giralt Declared no potential conflict of interest
Mauricio Jaciansky Declared no potential conflict of interest
Marcos David Pereira Declared no potential conflict of interest
Gonzalo Zeballos Declared no potential conflict of interest
The following faculty have provided no information regarding significant relationship withcommercial supporters and/or discussion of investigational or non-EMEA/FDA approved (off-label) uses of drugs as of 18 September 2017.
Roque Adan
Nicolás Bustos
Emiliano Garayalde
Raúl Eduardo Giglio
17
Roque Adan is the chief of the head and neckcancer surgery unit at Roffo Hospital.
He also works as chief surgeon in otherhospitals such as the British Hospital ofBuenos Aires and the Alexander FlemingInstitute. Among other activities, he alsocollaborated as Associate Professor insurgical oncology at Buenos Aires University.
20
Roque Adan
Chief Head and Neck Cancer SurgeryHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
21
Barbara Berenstein
Head and Neck SurgeonHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
Barbara Berenstein is a surgeon at RoffoHospital in Buenos Aires. She is specializedin head and neck cancer surgery and generalsurgery. Dr. Berenstein also works atAlexander Fleming Institute.
Nicolás Bustos graduated at the University ofBuenos Aires in 2009 and undertook aFellowship in PET/CT Imaging at theFundación Centro Diagnóstico Nuclear -CNEA in 2013-2015.
He currently serves as a radiologist at theInstituto Oncológico Roffo, where he is amember of the multidisciplinary Head andNeck cancer team. He furthermore worksfor other bodies such as the InstitutoAlexander Fleming and the FundaciónCentro Diagnóstico Nuclear.
22
Nicolás Bustos
RadiologistHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
23
Juan Manuel Carrera
Medical OncologistHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
Juan Manuel Carrera is a medicaloncologists specialized in Head and Neckand Breast cancer. He currently works atInstituto de Oncologia Angel Roffo, where healso underwent his residency. He is now partof the Head and Neck multidisciplinary teamand performs his work also in La Plata city.
Celeste Diaz graduated at the University OfBuenos Aires School Of Medicine. Shetrained in Clinical Oncology at Angel H. RoffoUniversity Hospital residency programmeand then joined the Head and neck unit as anattending physician.
Dr. Diaz also trained in evidence-basedmedicine, biostatistics and health technologyassessment. She is the coordinator of theHealth Technology Assessment area atNational Cancer Institute of Argentina since2015. She also participated in the 2016 WorldCancer Leaders’ Summit as a selected YoungLeader by the Union for International CancerControl (UICC).
24
Celeste Diaz
Medical OncologistHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
25
Emiliano Garayalde
Head and Neck SurgeonHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
Emiliano Garayalde studied in Mendoza atthe Universidad Nacional de Cuyo where hegraduated in 2005. He later on attended theCEMIC University Institute in generalsurgery.
Dr. Garayalde is currently a staff member ofthe Head and Neck Functional Unit of theIntituto de Oncologia Roffo in buenos Airessince 2013.
Raúl Eduardo Giglio was born In BuenosAires, Argentina. He studied medicine at theUniversity of Buenos Aires School ofMedicine and graduated in 1983. He completed a residency on internalmedicine (1984-1987) and the Fellowship inclinical oncology (1987-1989). He obtainedboth postgraduate specialties. Dr. Gigliobecame staff physician in the clinicaloncology department of the Instituto deOncología Ángel H. Roffo (1989). Currently,he works in the same institute as the Head ofclinical oncology.
26
Raúl Eduardo Giglio
Head Medical OncologyHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
27
Jordi Giralt
Radiation Oncology unitVall d’Hebron University HospitalBarcelona, Spain
Jordi Giralt focused his clinical research onthe treatment of head and neck cancer. Heparticipated to clinical trials regardingdifferent strategies for the treatment of H&Ncancer such as postoperative radio-chemotherapy (Bernier, NEJM), the use ofcetuximab (Bonner, NEJM, Lanct Onc),simultaneous chemo-radiotherapy (Rischin,JCO) or the use of panitumumab (Giralt,Lancet Onc). He also worked on radiotherapyquality control procedures (Peters, JCO orChristiaens, Radioth Onc) and strategies tominimize toxicity have also been a topic ofgreat interest. He furthermore contributed todifferent consensus and recommendationsand in the organization of conferences,courses and congresses on head and neckcancer such as the International ConferenceHead and Neck Oncology. He is the author ofabout 80 peer-review articles, of which over60% are focused on head and neck tumors.
Mauricio Jaciansky graduated from theFaculty of Medicine of the NortheasternNational University in 2005. He later obtainedthe specialty in General Surgery at theHospital J.R. Vidal in the province ofCorrientes city in 2010 and then performedthe specialty in Head and Neck Surgeryobtaining the Title in 2016.
Dr. Jaciansky is currently working at theOncological Institute Angel H. Roffo in theSurgery Department of the Head and Neckcancer Unit.
28
Mauricio Jaciansky
Head and Neck SurgeonHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
29
Marcos David Pereira
Medical and Radiation OncologistHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
He is also a member of the IndependentEthics Committee at Roffo Institute. In hisfree time he is an amateur photographer andan enthusiastic world traveller.
Marcos David Pereira is a Medical andRadiation Oncologist. He obtained hismedical degree at the National University ofLa Plata, in Argentina and, after a brief timeworking in a basic research lab, he startedhis residency in Medical Oncology at theAngel Roffo Oncology Institute, a cancercentre of the National University of BuenosAires. Having obtained his first medicalspeciality, he started his training in RadiationOncology, in the same hospital, as a fellowassociated to the National Commission ofAtomic Energy. By that time he workedactively in the Boron Neutron CaptureTherapy Program, an experimental form ofradiotherapy for advanced melanoma. Hehas participated in several clinical trialsrelated to melanoma and head and necktumours. He is responsible of radiotherapy inthe Units of Melanoma/Sarcoma, Head andNeck and Skin of the Angel Roffo OncologyInstitute and works in the education areas ofInternal Medicine of the School of Medicineof the University of Buenos Aires and theMedical and Radiation Oncology trainingsystems.
Gonzalo Zeballos graduated at the faculty ofmedicine of the National University ofTucuman, Argentina in 2006 and completedhis residency in Otorhinolaryngology (ENT) atthe Hospital Francés de Buenos Aires.
He is currently a member of the Head andNeck oncology team at Roffo Hospital inBuenos Aires and also works at CèsarMilstein Hospital at the department oflaryngology.
Dr. Zeballos is specialized in the use of Laserequipment technology and operates inseveral other bodies and Hospitals in BuenosAires.
30
Gonzalo Zeballos
ETN SpecialistHead and Neck Cancer UnitInstituto de Oncología Ángel H. RoffoBuenos Aires, Argentina
34
R. Adan (Argentina), R.E. Giglio (Argentina), M. Jaciansky (Argentina),G. Zeballos (Argentina)
Session I Overview on HNSCC
Learning objectives: • Recognize the complexity and heterogeneity of HNSCC and its clinical impact
• Describe trends in epidemiology and provide an overview of the diagnostic approach andstaging of head and neck cancers
• Review management approaches for HNSCC based on anatomical location
NOTES
35
N. Bustos (Argentina), J.M. Carrera (Argentina), E. Garayalde (Argentina), M.D. Pereira (Argentina)
Session II Multidisciplinary cancer care in HNSCC
Learning objectives: • Define rationale, methods and benefits for patients in working as part of a multidisciplinaryteam
• Describe general principles of each treatment modality
• Radiology: determine current imaging modalities and recommendations on modality choicefor each cancer subsite
• Surgery: define integration of therapy, assessment of resectability, primary tumor resection,margins, management of recurrence and surveillance.
• Radiotherapy: describe technical advances, radiation as primary and adjuvant treatment,palliative RT regimens
• Explain current available drugs and combinations and emerging options
NOTES
36
J.M. Carrera (Argentina), R.E. Giglio (Argentina), J. Giralt (Spain)Session IV HNSCC Treatment
Learning objectives: • Review current multimodality treatment options for locally advanced HNSCC
• Describe the biological heterogeneity of HNSCC and its impact on the individualization ofradiation therapy
• Acquire current treatment options for metastatic HNSCC (standard first line therapy,emerging options for second line treatment, immunotherapy)
NOTES
37
J. Giralt (Spain)KNLKeynote lecture
Learning objectives: • Provide elements on the Delphi methodology
• Analyze methods and results of the “First expert consensus using Delphi methodology fromthe Spanish Society for Head and Neck Cancer”
• Evaluate possible alternative applications of the Delphi methodology in the research onHNSCC
NOTES
All EXCEMED programmes are organized solely topromote the exchange and dissemination ofscientific and medical information. No forms ofpromotional activities are permitted. There may bepresentations discussing investigational uses ofvarious products. These views are theresponsibility of the named speakers, and do notrepresent an endorsement or recommendation onthe part of EXCEMED. This programme issupported by independent educational grantsreceived from Merck KGaA, Darmstadt, Germanyand Università Vita Salute San Raffaele, Milan, Italy.
48