Odds and Ends

• Drawing an EKG waveform properly• What to include in your hemorrhage

diagram (Tips and Help Schedule at http://webs.wofford.edu/davisgr/bio342/hemorrhagediagramtips.htm

– Hypovolemic shock?– Death?– Whatever you can do well in 15 minutes!

• Revised Abstracts may be turned in anytime but no later than the last Friday of class (Dec 7th.)

1QQ # 28 for 10:30Answer one

1. Diagram the response to a drop in oxygen delivery to the kidney.

2. Diagram the effects of sympathetic stimulation of systemic arterioles that leads to an increase in mean arterial pressure.

3. Diagram the effects of sympathetic stimulation of veins that leads to an increase in mean arterial pressure.

ACE expressed on luminal surface of pulmonary endothelial cells.

Gradient for CO2 is only 6 mmHg;CO2 is more 20x more soluble and permeable than O2

Ventilation by Bulk Flow

Gas exchange by Diffusion

Gas exchange

Where should the receptors be for the negative feedback loop for homeostasis?

Why the difference in partial pressures in Air and Alveoli?

Peripheral Chemoreceptors1) Carotid bodies (not carotid sinuseswhich are baroreceptors)2) Aortic bodies (not aortic arch baroreceptors)

Central Chemoreceptors in medulla (sensitive to H+ in interstitial fluid of medulla)

To ponder: Why should there be three sets of chemoreceptors?

RespiratoryPhysiologyThe physics of air flow

1) Flow in tubes

2) Ventilation

Poiseulle’s equation

Upper

Respiratory

Tract

The Structure underlying the function:

Lower

Respiratory

Tract

Bronchitis= infection/inflammation of conducting airwaysAsthma = smooth muscles contract →increase resistance to

airflow in conducting airways.

Intercostal muscles

Pneumothorax (unilateral due to each lung having its own compartment.

Greg R. and the story of spontaneous pneumothorax

Visceral pleura and parietal pleura separated by fluid-filled pleural cavity which allows lung and chest wall to slide relative to each other but remain adhered unless air enters the pleural cavity (which leads to collapse of the lung and outward expansion of chest wall on that side.)

Upper Tract Sleep Apneaa)obstructive,

b)central

&

CPAP

Continuous Positive Airway Pressure

Bronchopulmonary segments and Surgical resection

Bronchopulmonary segments and Surgical resection

Why is lung cancer so common?Why is lung cancer so common?

How are the delicate living tissues of the respiratory protected?

How are the delicate living tissues of the respiratory protected?