nootropic research.pdf

7/26/2019 Nootropic Research.pdf

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Nootropics. New formula |Research

by Oleg Filippenko

Introduction In order to produce a new nootropic stack, it is necessary to go through 2 phases of

research. The first phase consists of studying the most effective nootropics available today,

identifying the best chemicals and constructing a unique stack. The second phase will be

focused on testing the created mix, recording the effects and collecting a feedback from first

volunteers.

This research paper will be emphasised on the first phase of the research. The goal of this

stage is to create a stack that will be the most preferable among nootropic users. Namely,which enhances cognitive processes in the brain, boost the energy, memory capabilities,

improves literary fluidity, mood, protects and encourages generating the new brain cells,

reduces anxiety and depression. Apart from identifying the best nootropic elements, the

possible effects of the new stack will be described, the best format suitable for such

supplements will be determined and approximate amount of funds should be invested to

enter phase two of the research will be calculated.

Top Nootropics

The table below reflects the most commonly used nootropics both of chemical and natural

origin. Each element is given the characteristics of the effects, their estimated half-life,

dosage and possible mixture with the other substances.

Creating a new stack

After the detailed analysis of each nootropic in the table, the following elements were

chosen for creation of a new stack. They are Noopept, Aniracetam, Alpha GPC and

Pramiracetam.

As described in the table Noopept improves the memory and learning processes, boosts the

energy and amplifies the perception of colours and sounds. Aniracetam boost the mood,

creativity and social confidence. Alpha GPC is a choline which is an important ingredient of

any stack as inspite of being a chemical with nootropic qualities on its own, it cancels any

unpleasant side effects, that might be caused by racetams in the mix. The fourth ingredient

is Pramiracetam. This nootropic was chosen for its similar effects with phenylpiracetam, and

minimum side effects comparing with stronger racetams. Hence, the listed above nootropics

are expected to produce the most desirable effect when mixed.



The name of

nootropic

Half-life Characteristics Dosage Best Mix

Noopept 30-60 min

Anxiety, energy, focus, learning, memory

It’s effects are felt immediately after ingestion

Colours are brighter and sharper(similar LSD)

Enhances memory and learning

Similar to phenylpiracetam in regards to

instantaneous effects

From 1000 to 5000 times more potent than piracetam

Inexpensive comparing to other nootropics

In long term it strengthen your memory and makes

you recall things you forgot

Neuroprotective(for people who have cognitive

impairment)

Increases level of nerve growth factor and chemicals

that create new brain cell

Enhances functioning of both hemispheres

10-30mg a day Stack 1:

Alpha GPC 300mg

Piracetam 2g

Noopept 10mg

Stack 2:

Noopept 10mg

Aniracetam 1g

Sulbutiamine 300mg

Alpha GPC 300mg

Aniracetam 1-3 hours Learning, memory, mood,energy

Boosting mood, decreasing anxiety

No side effects

8 times stronger than piracetam

Improves speech flow and learning of abstract

concepts Creativity booster (enhances right brain funstioning

Vision is vivid and sharper

Social confidence

750-1500 mg

per day

Mix 1 (1-2 times a day):

Alpha-GPC 300mg

Aniracetam 750 mg

Mix 2:

Piracetam 1600mg

Aniracetam 400mg

Oxiracetam 400mg

Alpha-GPC 300mg



Phenylpiracetam 3-5 h One of the most potent nootropic 30-60 times

stronger than paracetam

Energizing( due to similarity to a phenethylamine,

such as Adderall)

Half-life 3-5 hours

Increases memory and cognition and protects the

brain(the best for studying and learning)

Make you tolerant to stress

Prevents and reduces the effects of amnesia

Enhances the mood and motivates

Increases stamina, recovery and endurance

No crash

Is on the anti-doping banned list

100-200mg up

to 3 times a

day;

Is not

recommended

to take daily

as tolerance

develops

quickly

Daily:

piracetam 4800 mg

Alpha GPC 300mg

Fish oil 2-4 caps

Multivitamin 6 caps

As needed for

study/workouts/test

(occasionally):

Phenylpiracetam 100-200

mg

Sulbutiamine 400-1000 mg

Oxiracetam 8 hours Enhances cognitive processes, attention, memory

learning capacity

Sensory perception, logical and analytical &

reasoning thinking

Amplifies mental and physical energy and increases

motivation

Protects brain and is safe in prolong consumption

5 times stronger than piracetam

Similar to phenylpiracetam with its smooth effects Potential treatment for Alzheimer disease and can

restore memory

Increases focus and concentration

Central nervous system stimulant

Reaching its peak within 1-3 hours of ingestion

800 to 2400

mg per day( 2

or 3 times of

400mg)

Mixture 1:

Oxiracetam 800mg

Alpha GPC 300 mg

Mix2:

Oxiracetam 800mg

Pramiracetam 200mg

Mix3:

Oxiracetam 800mg

Aniracetam 800mg



Lions’s Mane

Mushroom

N/A Mushroom (not a chemical)

Enhances cognitive function and neuroprotection

Increases the production of nerve growth factor

Reducing inflammation, encouraging neural growth

and improving overall brain health

Besides brains it treats cardiovascular health, obesity

and some types of cancer

Prevents and treats nerve damage

After several weeks of intake it improves depression

and anxiety

Boosts immune system by removing toxins from the

body

Typical

strength of

10:1

extract(30%

plysaccharide

content) 500-

3000mg per

day

Mixing (2x per day):

Aniracetam 750 mg

Alpha gpc 300 mg

Lions’s Mane Mushroom 2g

Fish oil 1g

Mixing 2 (1 per day):

Lion’s Mane 3g

Uridine 300mg

Fish oil 2g

Zinc 15mg

Alpha GPC 300mg

Ashitaba 10ml

Pregnenolone 5mg

Alcar 1g

L-Terosine 500mg

L-Theanine 2.5- 4.5 h

Naturally occurring in green teas

Boosts cognitive function

Increases serotonin and dopamine levels in the brain

Reduces stress levels and anxiety

Increases focus

100-200mg best to mix with caffeine with

2:1 ration

Sulbutiamine 5 hours Is a synthetic version of vitamin B1(which is

responsible for memory, length of focus, alertness

and mood in a body)

Boosts cognition, energy and mood

Reducing anxiety and nervousness

Varies

depending on

metabolism,

and personal

biochemistry:



Stimulates levels of dopamine

Improves memory

400-800 mg.

Alpha GPC 4-6hours

Choline nootropic (it naturally presents in a body in

small amounts)

Enhances memory and protects the brain from aging

Recover cell membrane after physical exertion

Promotes the release of dopamine

Enhances the effects of racetams

300-600 mg Mix:

Alpha GPC 300mg

Noopept 10mg

Aniracetam 800mg

Pramiracetam 5-6 h Improving memory, learning capacity,focus and

sensory perception( richer sounds and more vivid

colours)

5-30 times more potent than piracetam

Stimulates hippocampus(part of brain responsible for

memory creation), thus it is strong memory enhancer

Makes learning faster and easier

Boosts focus, rapid idea formation and clear thinking

Makes you more social

Recovers memory loss including Alzheimer and

amnesia

200-400mg

3x- day

Recommended to mix with

Racetams and cholines.



Within first 30 minutes of digesting the stack, a tester will start to feel the effects of

Noopept, namely the perception receptors will become more sensitive, colours will become

more vivid and sharper and sounds will be deeper. Furthermore, it is anticipated to have

energy boost, cognitive and memory improvements. After approximately 1 hour the effects

of Noopept will fade.

Aniracetam is estimated to produce effect after one hour and after 3 hours the effects will

start to disappear. Aniracetam will improve mood, creativity, literary fluidity and social

confidence. Pramiracetam is expected to be in action at the same time with Aniracetam.

This chemical will enhance focus, learning and memory abilities, clear thinking and rapid

idea creation. The effects of Pramiracetam will disappear in 5-6 hours. Alpha GPC as

mentioned before is crucial element for any stack, it will protect the cell membrane from

physical exertion, amplify the effects of racetams in the stack, slightly improve the memory

and prevent brain from aging.

While mixing different nootropics it is recommended to put the dosage slightly below the

regular amount, when the chemicals are used separately. Hence the dosage for one capsule

will be as follows:

Noopept 10mg

Aniracetam 600mg

Alpha GPC 300mg

Pramiracetam 300mg

Total 1210mg

The natural nootropics were not chosen due to their low density and potency, meaning that

they occupy too much space in the capsule/pill producing minimum effect. However, those

types of nootropics might be used in creating the “natural stack” in the future.

Form of Consumption

There are various forms of consuming supplements. They are tablets, caplets, capsules,

softgels, chewables, powders and liquid types. Tablets or pills are considered to be the most

cost effective, the most amount of powder can be fitted in there, comparing to all other

formats, the shelf-life of tablets is the longest as well. Capsules are a bit more expensive to

produce, and less milligram of powder can be fitted in them as the material is not

compressed. Furthermore, the life of capsule is shorter than of pill. Sofgels and liquid are

not applicable in this case. Chewables can fit the least amount of material. Powders are not

convenient to use and have the shortest life.

Disregarding the apparent advantages of pill form, in this research capsule form will be

used, as it will be cheaper to produce it at home. Pill pressing machine is 10 times more

expensive than capsule filling machine.



There are several sizes of a capsule. They are 000, 00, 0, 1, 2, 3, 4 and 5. The biggest capsule

is 000 and can fit from 800 to 1600mg of powder depending on the density of the material.

This capsule should be big enough to fit 1210mg of our new stack

Necessary equipment

In order to start the experimenting stage, the following equipment should be acquired:

Item name Approximate price/quantity

Empty gelatine capsules 000 $29,21(500caps) in amazon

Capsules filling machine for 000 $109 on ebay

A milligram scale $28 on ebay

Nootropics: Form PowderCity:

Noopept $9.74 for 5gAniracetam $31.36 for 100g

AlphaGPC $33.22 for 50g

Pramiracetam $82.25 for 50g

Total $322.78

Apart from the equipment and materials to purchase listed above, we need to consider the

import charges that might occur when we bringing those nootropics to Australia in larger

amounts.

There is an Australian company called Platinum Freight Management, which can provide us

with advisory services related to import for just $88 for 6 months. Thus, by getting advice

from lawyers we will be able to avoid any fines which can cost us thousands dollars.

Conclusion

Overall, the nootropics that can be considered for a new stack are Noopept, Aniracetam,

Alpha GPC and Pramiracetam with the total dosage of 1210 mg will be put in the 000-sized

capsule. The total amount of money required to conduct the second phase of research is

$322.78. The next step is to test the formula created above and record its effectiveness.

If testing phase shows us that the products need significant improvements, the research

phase 1 of creation of a new stack should be conducted again. In contrast, if the testing

stage brings positive results about the stack, the formula will be given to the neuro-

scientists in laboratory to test it with more professional equipment, add or remove some

ingredients and finalise the product.



References:

1. All Star Health (http://www.allstarhealth.com/blog/products-and-ingredients/tablets-

capsules-liquids-powders-chewables/)

2. Brain Tropic (http://www.braintropic.com/)

3. Capsuline (https://www.capsuline.com/empty-capsule-size-chart/)

4 Platinum Freight Management (https://platinumfreight.com.au/customs-clearance-

advice/)

http://www.allstarhealth.com/blog/products-and-ingredients/tablets-capsules-liquids-powders-chewables/




http://www.braintropic.com/



https://www.capsuline.com/empty-capsule-size-chart/







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