NIST: Promoting U.S. Innovationand Industrial Competitiveness

Focus on Microfluidics

Clara Asmail

Technology Marketing Program ManagerTechnology ServicesNational Institute of Standards and TechnologyU.S. Department of Commerce

NIST patented technologies NIST patented technologies to be presented tonight :to be presented tonight :

Microfluidics portfolioMicrofluidics portfolio

Simple High-Performance Biochemical Analysis Simple High-Performance Biochemical Analysis

Methods For Polymer Microfluidic FabricationMethods For Polymer Microfluidic Fabrication

Microfluidic Mixing And Flow ManipulationMicrofluidic Mixing And Flow Manipulation

Uniform Assembly Of NanoliposomesUniform Assembly Of Nanoliposomes

Surface immobilization of biopolymers Surface immobilization of biopolymers

What are Microfluidics?

Precise control and manipulation

of very small fluid flows

~ on the order of  microliters or nanoliters  

** a drop of water is approximately 25 microliters 

Microfluidics conserves costs in biomedical research

Small volume of fluids in microfluidic channels translates to:

Small amounts of reagents and analytes used

&

Integrated process steps – simpler, faster

Industrial Applicationsfor instrumentation suppliers

Pharmaceutical & Biotech $600 B

Diagnostics $30 B

Medical Devices $200 B

Drug Delivery $91 B (by 2009)

$220 B (by 2015)

Emerging Markets for Microfluidics Applications

Geraldine Andrieux Gustin 

Yole Development

June, 2007

Microfluidics: Market size expectations

2005 global market for microfluidic technologies ~ $2.9B

by 2011 should grow to ~ $6.2 B

i.e., an average annual growth rate of 14.1%

Microfluidics TechnologyBCC Research

September, 2006

Companies currently in Microfluidics market space:

3M Caliper LS

Bartels mikrotechnik Gyros

Boehringer Ingelheim microParts Diagnoswiss

RainDance Technologies Dyconex

eGene Eksigent Technologies

Fluidigm Genesystems

Microplumbers Nanogen

IQ micro Wilden AG

Weidmann Plastics Epigem

Micralyne Microfluidics chip shop Micronics

Micronit microfluidics Wasatch microfluidics

ThinXXS SpinX Technologies

Microfluidics: Critical market segments

drug discovery

drug delivery

in-vitro diagnostics

ink jet printing --- mature

chemical analysis

high-throughput screening

Microfluidics will enable

efficient screening

of more drugs in less time

and drastically cut down the costs

of drug development.

NIST technology presentationsNIST technology presentations

Dr. David Ross

Simple High-Performance Biochemical Analysis

Methods For Polymer Microfluidic FabricationMicrofluidic Mixing And Flow Manipulation

Uniform Assembly Of Nanoliposomes

Dr. Michael Tarlov

Surface Immobilization Of Biopolymers