nd global summit and expo on nanotechnology and material...

Proceedings of

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Nanotechnology and Material ScienceAugust 27-28, 2018 | Rome, Italy

2nd Global Summit and Expo on

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Keynote Forum- Day 01

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Iron Oxide Nanostructures with Tunable Porosity and High-index Facets for Catalysis

Inorganic nanomaterials have been used in widespread applications such as nanophotonics, nanoelectronics, catalysis, energy conversion and storage, and so on. It is well known that the properties of nanomaterials largely depend on their morphology,

size and surface structure. To enhance and exploit their applications, it is essential to prepare nanomaterials in a controllable manner. Many inorganic materials with different nanostructures have been successfully prepared. However, it remains a big challenge to synthesize some complex nanostructures, such as non-spherical hollow structure and structures enclosed by high index facets. Moreover, there are still lack of the fundamental understandings of the nanocrystal growth mechanisms. In this work, we will focus on the rational synthesis of complex nanostructures (e.g. non-spherical hollow structure, porous structure, high index facets structure) as well as their growth mechanisms and applications. We demonstrated two different strategies (i.e. templating method and chemical etching) to prepare α-Fe2O3 non-spherical hollow nanostructures. The hollowness and porosity can be easily tuned by chemical etching. Spindle- and platelet like α-Fe2O3 hollow structures were synthesized using a chemical etching method. The hollowness and porosity could be easily tuned by varying the amount of etchant. By comparing the performance of samples with similar morphologies and particles sizes but different hollowness and porosities, we can get an intuitive understanding of the beneficial effects of hollow and porous structures on photocatalytic activity and get a better understanding of the advantages of hollow and porous structures. We further synthesized α-Fe2O3 concave nanocubes enclosed by high-index 13-44 and 12-38 facets as well as hollow interiorsvia a facile hydrothermal route based on kinetically controlled overgrowth. The as-synthesized sample exhibited superior catalytic activity and high stability for low temperature CO oxidation.

BiographyZhoucheng Wang has his expertise in materials electrochemistry and surface coating’s technology. His research interests concern electrochemical processing and char-acterization of nano-composite materials and multi-layer coatings, energy conversion and storage, corrosion performance of metals in various environments and surface engineering. He has undertaken some projects in many areas, such as gradient functional nano-composite biomaterials, bipolar membranes and applications, corrosion and protection of magnesium alloys, etc. His research also focuses on solid state electrolyte, supercapacitor and electrocatalysis.

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Zhoucheng WangXiamen University, China

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Bright-exciton fine-structure splittings in single perovskite nanocrystals

The electron-hole exchange interaction (e-h EI) is greatly enhanced in quantum-confined semiconductor nanostructures, leading to the energy-level splitting between bright- and dark-exciton states. In semiconductor epitaxial quantum dots

(QDs), the dark excitons are generally nonemissive without applying a magnetic field and the bright-exciton state is further divided into two orthogonally- and linearly-polarized ones. A complete elimination of this bright-exciton FSS has been actively pursued to realize a polarization-entangled photon-pair source for fundamental tests in quantum mechanics and optics, as well as for practical applications in quantum communication. Interestingly, the dark excitons in colloidal semiconductor nanocrystals (NCs) are normally emissive, while the bright-exciton FSS was rarely observed.

Semiconductor colloidal perovskite NCs have just emerged as a novel type of semiconductor nanostructure capable of emitting single photons without the influence of dark-exciton emission [1]. Moreover, the suppressions of both the photoluminescence (PL) blinking and spectral diffusion effects were successfully demonstrated in single perovskite CsPbI3 NCs [2]. Here we show that the bright-exciton FSS can be easily observed in single CsPbI3 NCs at the cryogenic temperature, with an energy separation as large as hundreds of μeV between the two orthogonally- and linearly-polarized states [3]. With the laser excitation at an intermediate power, this PL doublet of neutral single exciton would switch to a single peak of singly-charged single exciton. When the laser power is further increased, PL doublets from neutral biexciton, charged biexciton and doubly-charged single exciton could be additionally observed. Based on the FSS values obtained from various exciton species, the isotropic and anisotropic e-h EI energies can be roughly estimated, which have provided valuable information on the fundamental electronic processes in these novel perovskite NCs.

Acknowledgments: This work is supported by the National Basic Research Program of China (2017YFA0303700), the National Natural Science Foundation of China (Nos. 11574147, 91321105, 11274161 and 11621091), the Fundamental Research Funds for the Central Universities, and the PAPD of Jiangsu Higher Education Institutions.

BiographyXiaoyong Wang obtained his bachelor’s and master’s degrees of optical engineering from Tianjing University, China, and his doctoral degree in physics from University of Arkansas at Fayetteville, US. After doing his postdoctoral researches from University of Texas at Austin and University of Rochester in the US, Xiaoyong Wang took a full professor position at Nanjing University, China, and is now the chair for the department of optical science. His group is now utilizing the single-particle and ultrafast spectroscopic techniques to study various semiconductor nanostructures such as epitaxial quantum dots, colloidal nanocrystals, 2D materials and single-walled carbon nanotubes. The fundamental research projects of the group include single-photon emission, energy transfer, carrier multiplication and coherent optics of semiconductor nanostructures, the purpose of which is to facilitate their practical applications in quantum information processing and optoelectronic devices.

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Xiaoyong WangNanjing University, China

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Nanoscale engineering of plasmonic materials for biosensing and bioimaging

Early diagnosis plays an increasingly significant role in current clinical drive. Detection, identification, and quantification of low abundance biomarker proteins form a promising basis for early clinical diagnosis and offer a range of important medical benefits. Amplification

of light from NIR fluorophores by coupling to metal nanostructures, i.e. Metal Induced Fluorescence Enhancement (MIFE), represents a promising strategy for dramatically improving the detection and quantification of low abundance biomarker proteins, and potentially increase already sensitive fluorescence based detection by up to three orders of magnitude. The amplification of the fluorescence system is based on interaction of the excited fluorophores with the surface plasmon resonance in metallic nanostructures. The enhanced fluorescence intensity due to the existence of metal nanostructures makes it possible to detect much lower levers of biomarkers tagged with fluorescence molecules either in sensing format or for tissue imaging. The first part of my talk will focus on some recent developments of plasmonic metal nanostructures by both “top-down” and “bottom up” methods. I will then discuss the prepared plasmonic nanostructures in the applications of biosensing and bioimaging, with the emphasis on plasmonic enhancement towards NIR I and NIR II regions.

BiographyFang Xie is a Senior Lecturer at Department of Materials, Imperial College London. She is also Deputy Director for MSc in Advanced Materials. She has expertise in func-tional nanomaterials including metal, semiconducting, and oxide nanomaterials synthesis, as well as the applications of the functional materials in energy and life sciences. Her current research interests include plasmonic nanostructures for efficient light harvesting for solar cells and solar fuels, as well as in ultrasensitive biosensing and Bioimaging applications. She has over 60 publications including five patents. She has also delivered a number of keynote and invited talks in the international conferences.

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Fang XieImperial College London, UK

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Workshop- Day 01

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Construction of recombinant human collagen polypeptides/chitosannano-porous scaffolds for wound healingStatement of the Problem: A tissue-engineering scaffold acts as a substitute for thenative extracellular matrix (ECM) and plays a crucial rolein tissue regeneration. Native ECM is mainly composed of nano-scale collagen fibers and proteoglycan. To mimic the structure and components of ECM, electrospinning the only method that could produce continuous fibers on the micro or nano scales was used to produce collagen and chitosan nanofibers. However, the electrospun collagen/chitosan nanofibers has been proved challenge as toxic, corrosive solvents such as hexafluoroisopropanol and trifluoroacetic acid are frequently involved. This may cause cytotoxicity during in vivo transplantation. Traditionally, after the collagen/chitosan nanofibers prepared, crosslinking is conducted to improve the properties, however this is tedious and inhomogeneous.At the same time, collagen derived from animal species,

creating concerns of quality, purity, disease transmission and allergic reactions.

Methodology & Theoretical Orientation: In our lab, a reliable,predictable and chemically defined recombinant human collagen polypeptides (RHC)without allergenicity were prepared and it was used to replacecollagen. Since RHC is water-soluble, a mild electrospinning solvent prepared from diluted acetic acid and ethanol was used to makeRHC/chitosan electrospinning successful.At the same time, crosslinking in situ was applied to simplify the procedures of nanofibers preparation.

Findings: By mediating the ratio of RHC, chitosan and polyethylene oxide (PEO), uniform nanofibers with 100-700 nm were prepared. In vitro study indicated that cells could maintain good viability when grew on nanofibers, and in vivo study further confirmed wounds healing could be acceleratedas nanofibers applied.

Conclusion & Significance: RHC/chitosan nanofibers are biocompatible and have potential in tissue engineering. Moreover, the simplified and cost-effective fabricating procedures could make the application successfully in large-scale.

BiographyShulin Yang is the Professor of Institute of Environmental and Bioengineering at the Nanjing University of Science and Technology. His research is in areas of biomateri-als, tissue engineering and regenerative medicine. He is devoted to researches of electrospinning nanostructures, hydrogels construction and 3D printing technology. In addition, Prof. Yang also working on cell engineering, gene engineering and fermentation engineering.

Yang received Foundation of the National High Technology Research and Development Program of China (No: 2014AA022107), Special-funded programme on national key scientific instruments and equipment development (2012YQ0401400803), et.al. He has published more than one hundred of sci papers, obtained lots of authorized patented, and has made many programs industrialize.

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Aipeng Deng is also affiliated with Nanjing University of Science and Technology, China. His research interests include Biomedical Engineering, Bioengineering and Materials Engineering.

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Shulin Yang & Aipeng DengNanjing University of Science and Technology, China

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Speakers- Day 01

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2d materials for ubiquitous electronicsSaptarshi DasPennsylvania State University, USA

The interest in two dimensional (2D) materials is rapidly spreading across all scientific and engineering disciplines due to their exceptional properties, which not only provide a platform to investigate intriguing physical phenomena but

also promise solutions to the most relevant technological challenges. It is undisputed that silicon has been the DNA of our technological evolution for the last several decades. However, with the emergence of the era of Internet of Things (IoT), novel materials need to be mutated into the genetics of the modern technologies in order to meet the ever increasing demand of new functionalities. In this context, the 2D layered materials like MoS2, WSe2, Black Phosphorus, Graphene and many more find their application in various electronic application which includes ultra-low-power electronics, brain-inspired electronics, space electronics, anti-corrosion electronics, flexible electronics, as well as digital electronics. In fact, field effect transistors, radiation sensors, bio-detectors, optical modulators, and neuromorphic devices with superior performances have already been demonstrated based on different 2D materials. A major challenge towards the commercialization of 2D materials is the large area, scalable and controllable growth of highly crystalline monolayers in a cost effective way. In this context, chemical vapor deposition, liquid phase exfoliation and electrochemical synthesis approaches are showing a lot of promise. My talk will provide a holistic understanding of 2D materials starting from large area synthesis to device fabrication to different electronic, optoelectronic and neuromorphic applications.

BiographySaptarshi completed BE degree (2007) in Electronics and Telecommunication Engineering (ETCE) from Jadavpur University, India and PhD degree (2013) in Electrical and Computer Engineering (ECE) from Purdue University, USA. He worked at the Department of Defense’s Argonne National Laboratory as a postdoctoral research scholar during 2013-15 and as an Assistant Research Scientist during 2015- 16. He joined the Department of Engineering Science and Mechanics (ESM) and Material Research Institute (MRI) at the Pennsylvania State University as an Assistant Professor from January, 2016. His research group primarily focuses on the experimental investigation of novel nano materials (especially 2D materials like MoS2, Black Phosphorus, Graphene and 1D materials like CNTs and Nanowires) for innovative device ideas. His research group (https://sites.psu.edu/sdas/) works on high performance and low power electronics, flexible electronics, optoelectronics, bioelectronics and energy harvesting devices.

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In-silico modeling of degrading nanomaterials as a novel approach for tumor therapyStefaan J Soenen1,2, Manshian BB1,2, Pokhrel S3, Himmelreich U2, Tämm K4, Sikk L4, Fernández A5, Rallo R5, Tamm T4, Mädler L3

1NanoHealth and Optical Imaging Group, Belgium2Department of Imaging and Pathology, Belgium3University of Bremen, Germany4University of Tartu, Estonia5Universitat Rovira i Virgili, Spain

Here, our aim was to develop ZnO NMs with finely tuned degradation kinetics in order to maximize cancer-cell specific cell death. ZnO NMs were doped with different levels of Fe ions. Based on the intrinsic physicochemical properties of

the NMs, quantitative nanostructure-activity relationship models were generated to define the dissolution rate and cell death of the different NMs and to generate an optimal formulation for toxic-by-design NMs that could selectively kill cancer cells while non-cancerous cells remained unaffected. Cytotoxicity of these NMs was tested in HeLa and KLN 205 (cancerous), MSC and BEAS-2B (non-cancerous) cell lines. Data revealed that low Fe-doping caused higher overall toxicity that was diminished as the Fe-doping increased. In-silico analysis revealed that 2% Fe-doped NMs were the most selective towards cancer cells. These findings were confirmed in co-culture models where cancer cells were cultured with non-cancerous cells and exposed to the NMs. This was further evaluated in a syngeneic mouse model (DBA/2 mice with subcutaneous KLN 205 cells). Upon administration of pure, 2%, or 10% Fe-doped ZnO, the level of Zn2+ ions present in the tumor were inversely correlated to the Fe-doping level. The pure ZnO NMs were found to be toxic to the mice, while 10% Fe-doped NMs did not cause any toxicity nor a major therapeutic benefit. However, 2% Fe-doped NMs resulted in a clear reduction in tumor growth, without any negative effect on animal well-being. Thus, we have demonstrated that through controlled dissolution and in-silico modelling, NMs can be generated that cause selective cancer cell toxicity.

BiographyStefaan J Soenen is from NanoHealth and Optical Imaging Group at KU Leuven. He was awarded an ERC Starting Grant (NanOnc), excellence in science professorship and am scientific coordinator of the optical imaging section in the Molecular Small Animal Imaging Center (MoSAIC). His research focuses on studying the biological behavior of nanomaterials for biomedical purposes focusing on the development of high-throughput cytotoxicity models optimized for nanoparticle analysis and the use of in-vivo optical imaging methods for studying the biodistribution and therapeutic efficacy of NMs. His work involves developing novel ways for optimizing NM mediated anti-cancer therapy through alternative therapeutic approaches or by increasing delivery of NMs to the tumor site.

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A personalized approach for the delivery of nanomaterial based cancer therapeuticsBella B Manshian1,2, Uwe Himmelreich2, Stefaan J Soenen1,2

1NanoHealth and Optical Imaging Group, Belgium2Molecular Small Animal Imaging Center, Belgium

Cancer drug concentrations are calculated based on individual’s weight. In nanotherapy this does not always lead to optimal therapeutic results. Thus, we aimed to correlate the nanoparticleconcentration to the size and metabolic activity of the

individual tumor. Here, the cytotoxicity of CdTe quantum dots (QDs)was evaluated using ahigh content imaging approach for evaluating bio-nano interactions. In-vivo, the exposure of the mouse lung tumor cells (KLN 205) to 13.91*107 NPs/cell resulted in 20% acute (at 24 h) cell death while 10% acute cell death was achieved with 10.43*107 NPs/cell. We then used non-invasive optical imaging to determine the metabolic activity of the individual tumor, in a syngeneic tumor model (in DBA2 mice), based on which we provided fluorescent QDs at toxic levelsat personalized concentration and at a general average dose. The animals were either given saline (control animals) or saline containing 435 or 318 μg QDs (standard reference groups GHequal (20% cell death) and GLequal, (10% cell death) respectively), or 362–480 or 269–361μg QDs personalized medicine groups GHRel (20% cell death) and GLRel, (10% cell death), respectively).The results showed impeded growth for all treated tumors compared to control animals. Only animals with personalized dosages displayed significant effects even at low QD concentrations, while at average dosages these results were obscured due to high variability. Furthermore, tumor therapeutic activity could be monitored using noninvasive imaging as anticancer efficacy correlated with loss in fluorescence intensity thusfacilitating the monitoring of therapeutic delivery and optimal NP-mediated cancer treatment via personalized medicine.

BiographyBella research focuses on nanotoxicology and the manipulation of nanomaterials for in-vivo theranostic applications. She has been using multimodal and multiparametric in-vivo imaging, of mainly preclinical animal models, to assess disease mechanisms and therapy accompanied with screening of individual nanoparticle toxicity, the mechanisms involved and cellular-nanoparticle interaction kinetics. Her interest is in developing non-invasive methods for the dual function of visualization and tracking of specific cell types with a strong focus on tumor cell, stem cell, immune cell and beta cellswhile simultaneously delivering therapeutic agents. She has over 42 publications plus 3 book chapters (H index: 16, 1445 citations).

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Green TechnologyAndreas NicholasST GO LAB Inc., USA

S†Go Lab is a nanotechnology and AI research company, focused on the development of Green Energy solutions aimed at ensuring a better life for people around the world. Currently tackling the water purification challenge, we aim to

bring sustainable solutions for a better future. As water is Earth’s most precious resource, we have dedicated time to use these nanotechnologies to filter water, restore natural habitats and preserve endangered flora and fauna, while maintaining harmony throughout the Biosphere. Nano-filters will provide water to the thirsty, while purifying the waste of the mining and agricultural industries. These materials will also be used to monitor the health of billions of people and contribute toward a more sustainable, industrial Tomorrow.

BiographyAndreas Nicholas is a material science manufacturing engineer, specialized in Nanotechnology, who leads the design of water filtration systems with S†Go Lab. Originally from Santa Cruz, California, after having lived in South America and Europe, he focuses on the technology available for new alternative uses and environmental solutions. In 2012, Andreas discovered an economic method of graphene ablation, offering a new and economical world of applications for this cutting-edge material.

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Fabrication of Polycaprolactone (PCL) graphene nanocomposites by solution intercalationKamal Yusoh and Tan Li SanUniversiti Malaysia Pahang, Malaysia

Recently, biodegradable polymers like polycaprolactone (PCL) gain the attraction from the researchers because non-biodegradable fossil fuel based polymers lead to many waste and environmental issue. However, low glass transition

temperature, low mechanical property, high permeability and slow crystallization rate restrict PCL to be used in a wide range of applications. Therefore, the innovation of PCL nanocomposites with good mechanical, thermal, barrier and degradable properties is highly demanded by the market. In order to achieve this objective, a study of graphene as the nanofiller for PCL matrix was carried out to determine the weight percentage that will produce the nanocomposites with the optimum degradable and barrier properties. PCL/graphene nanocomposite was fabricated by using solution intercalation method. Then, characteristics analysis of the nanocomposite was done by Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD) and Field Emission Scanning Electron Microscopy (FESEM). In morphological analysis, nanocomposite with 0.01 wt% and 0.05 wt% of graphene show better exfoliation and intercalation with PCL matrix. Weathering test was carried out by using Accelerated Weathering Tester to indicate the photodegradable properties of nanocomposite. The additional of graphene to PCL matrix not affect the initial photodegradable ability of PCL. Meanwhile in chemical degradation test conducted by using 10% hydrochloric acid and 10% sodium hydroxide, PCL with 0.05 wt% of graphene possessed the best chemical resistance towards acid and basic conditions. Water vapour permeability test was used to predict the barrier properties. All nanocomposite samples show significant improvement in reduce the permeability. The addition of small amount graphene is able to reduce up to 80% of PCL permeability. In summary, PCL with 0.05 wt% of graphene show the best improvement in all the properties tested, while nanocomposite with 0.10 wt% of graphene presented poorer result due to the agglomeration of graphene.

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Aminothymoquinone and curcumin dye sensitized solar cellsMehboob Nagarbawdi1 and Sohail Bagwan2

1Poona College, India2Abeda Inamdar Senior College, India

Dye-sensitized solar cells (DSSC) based on natural sensitizers have become a topic of significant research because of their importance in the field of energy conversion. In our study we have used curcumin and aminothymoquinone ar natural

dye sensitizers. Aminothymoquinone is an important constituent of Nigella Satvia. It is very important light sensitizer. The dye molecules are absorbed by TiO2 nanoparticles at the surface, when submerged in the solution for 24 hrs. When illuminated under 80W/cm2 intense light the photovoltaic properties were investigated and the current density-voltage characteristics and current conversion efficiency measurements were carried out. The short-circuit current (Isc), open circuit voltage (Voc), Fill factor (FF) and efficiency (η) for both the dyes were determined. Comparatively the aminothymiquinone dye as light harvesting material was found to be a more promising candidate for future solar cells. Further being natural dyes both these have minimum impact on the environment.

BiographyMehboob Nagarbawdi is an erudite academician with high calibre and extensive experience of over 27 years, developing results driven curriculum and delivering enthusiastic instruction of Physics principles to students. Thirty five students have completed research, under my supervision in Material Science. He Published books on “ELEMENTS OF MATERIAL SCIENCE, QUANTUM MECHANICS, PHYSICS OF NANOMATERIALS and ELECTRONICS.” He also Contributed as a Resource Person at several International / national / state level as well as university level seminars/ conferences/ workshop/ symposia.( Turkey, Thailand, Malaysia, Goa). He Participated and presented paper International / national / state level as well as university level seminars/ conferences/ workshop/ symposia. He is a Chairman of Science and Technology Advisory Committee, Indo Global Chamber of Commerce, Agriculture and Industries.

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Keynote Forum- Day 02

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Nano-particles for high-perf’ EV batteries and lightweight vehicles

Size is of the essence. Just see two very different applications examples of nano materials:

1. High capacities Li-ion batteries for EV : the existing Li-ion technology uses graphite. Nanomakers silicon particles enable the manufacturing of high capacities (x2-3) Li-ion batteries anodes along with a high capacity retention along cycling (up to 500 cycles). For silicon anodes, various formulations are studied which do not change the anode preparation existing processes. The carbon coating of the particles improves the anode performances during cycling, especially the capacity stability.

2. Aerospace devices and automotive lightening : University of Wisconsin and Eck Industries issued a proof of concept of a fine dispersion of silicon carbide nanoparticles into melting aluminium. Multiple mechanical benefits (improved tensile and fatigue strength, improved stiffness, improved fracture toughness) of the use of Nanomakers nano-silicon carbide, have been demonstrated, compared to their micrometer sized alternatives. Based on the powder metallurgy route, the HIPERCO project (financed by EIT Raw Materials) is developing an innovative silicon carbide / aluminium nano-composite powder for additive manufacturing. Those silicon-based particles are produced with a very narrow particle size distribution by a laser pyrolysis process developed by CEA. This process is reproducible, robust and the particles have low oxygen and very low impurities contents. This presentation details the “nano-effect” : how nano materials bring much more than the coarse form of the same materials.

BiographyAn engineer with a PhD, Jean-François Perrin has over twenty years experience in GM positions in innovative industries, particularly for the development of new activities and the implementation of industrial production facilities in an international environment. He worked in large international groups (Siemens, Saint-Gobain, Suez-Environ-ment) but also in SMEs. He has been the CEO of MPO Energy, a start up devoted to designing and manufacturing innovative photovoltaic cells.

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Jean-François PERRINChairman and CEO, Nanomakers, France

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Workshop- Day 02

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Monolithic 3D self-rolled-up membrane nanotechnology for high integration level RF and power electronics applications

Wen HuangHefei University of Technology, China

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Speakers- Day 02

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High-k oxides coatings with antibacterial properties – new application in medicineAnna Słońska-Zielonka1, Joanna Cymerys-Bulenda2, Rafał Pietuszka3, Michał M Godlewski1, Marek Godlewski31Warsaw University of Life Sciences, Poland 2Warsaw University of Life Sciences, Poland3Polish Academy of Sciences, Poland

The increasing resistance of bacteria to antibiotics has become the dominant problem on a global scale and a serious challenge for modern medicine. For that reason, it is very important to develop new, effective and low-cost technologies

enabling the development of new strategies aimed at the elimination of pathogenic bacteria. Recently, special attention has been paid to high-k oxides and their antibacterial properties, due to which they can find new application in biology, medicine and food industry.

Atomic layer deposition (ALD) allows deposition of the thin films of high-k oxides on various materials, including temperature sensitive ones (e.g., perishable fabrics), equipment and instruments (including implants) used in hospitals. In the current study we evaluated the antibacterial properties of various high-k oxides (ZnO, HfO2, TiO2, ZrO2, Al2O3, AZO) deposited by the ALD. Testing of antimicrobialaction was performed according to the agardisk diffusion method, commonly used to determine the sensitivity of bacteria to antibiotics. Paper discs coated with high-k oxidesnanolayerwere placed on the surface of the bacteria-covered medium. In the experiment reference bacterial strains, as well as wild serotypes were used. The efficiency of antibacterial properties of high-k oxides was evaluated by the extent of the area in which bacteria growth was inhibited.

In conclusion, antibacterial nano-coatings are a new alternative (to disinfectants and antibiotics) that could help to reduce the number of infections. Moreover, the low temperature of layer deposition opens a possibility to coat various multidimensional materials, such as soft tissue paper, fabrics, surgical instruments and other implements, thus promising a range of new potential applications in medicine, veterinary and broader health care.

Acknowledgments: The research was partially supported by the National Centre for Research grants “Maestro” 2012/06/A/ST7/00398 and “Sonata-Bis” UMO 2012/05/E/NZ4/02994 supported by the grant from 05-1/KNOW2/2015 “Healthy Animal-Safe Food”.

BiographyAnna Słońska-Zielonka, PhD is currently the Post-doc Researcher at the Faculty of Veterinary Medicine, WULS-SGGW. She defended the PhD in 2013. Her recent scientific interest relate to the development of nanoparticles for bio-medical applications. She is author / co-author of 33 papers in the WoS database and 3 chapters in academic monographies, cited over 100 times. 23 national and international prizes and medals for innovation (in 2012-2017) reflect the relevance of her research.

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Antibacterial printing vanishes – new application in food industryJoanna Cymerys-Bulenda1, Anna Słońska-Zielonka2, Jarosław Kaszewski3, Michał M Godlewski2, Marek Godlewski31Warsaw University of Life Sciences, Poland2Polish Academy of Sciences, Poland3Warsaw University of Life Sciences, Poland

Contamination of food with pathogenic microorganisms causing food-borne diseases poses a real threat to human health. One of the methods to reduce the food contamination is the use of food packaging with antibacterial properties (active

packaging). They prevent adverse changes in food quality by destroying microorganisms or inhibiting their growth. Hence, we proposed application of nanopowders with antibacterial properties introduced to the polygraphicvanishes used to seal the surface of printed materials. Zinc oxide, nanoparticles with confirmed antibacterial properties in substantia / in nanolayer, were added to the commercial vanishes of either aqueous (ABV, dispersive vanish) or organic (OBV, offset vanish) solvent base. They were printed on 240 g/m2 paper sheets and then cut in sterile conditionsinto 1cm2 samples. Antibacterial properties were checked withthe agar disk diffusion method using reference and wild-type (isolated from the clinical cases) bacterial serotypes. Samples were placed on the surface of the bacteria-covered medium. The efficiency of antibacterial activity of varnishes mixed with zinc oxide was measuredas the extent of the area inwhich bacteria growth was inhibited. Varnish layers with the addition of ZnO nanoparticles showedantibacterial / bacteriostatic activity against common bacterial strains, bothopportunistic, pathogenic and common bacteria causing losses in the food industry. According to the obtained results we can conclude that the addition of ZnO to the vanishes add antibacterial properties to the final print. Nanoparticles-enhanced vanishes showed antibacterial and bacteriostatic properties; therefore it can find potential applications in medicine, broader health care, and food industry.

Acknowledgments: The research was partially supported by the National Centre for Research grants “Maestro” 2012/06/A/ST7/00398 and “Sonata-Bis” UMO 2012/05/E/NZ4/02994 supported by the grant from 05-1/KNOW2/2015 “Healthy Animal-Safe Food”.

BiographyAnna Słońska-Zielonka, PhD is currently the Post-doc researcher at the Faculty of Veterinary Medicine, WULS-SGGW. She defended the PhD in 2013. Her recent scientific interest relate to the development of nanoparticles for bio-medical applications. She is author / co-author of 33 papers in the WoS database and 3 chapters in academic monographies, cited over 100 times. 23 national and international prizes and medals for innovation (in 2012-2017) reflect the relevance of her research.

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Clean energy for cooling and heating with ground source heat pumpsAbdeen OmerEnergy Research Institute (ERI), United Kingdom

In the recent attempts to stimulate alternative energy sources for heating and cooling of buildings, emphasise has been put on utilisation of the ambient energy from ground source heat pump systems (GSHPs) and other renewable energy sources.

Exploitation of renewable energy sources and particularly ground heat in buildings can significantly contribute towards reducing dependency on fossil fuels. The study was carried out at the Energy Research Institute (ERI), between September 2016 and November 2017. This paper highlights the potential energy saving that could be achieved through use of ground energy source. The main concept of this technology is that it uses the lower temperature of the ground (approximately <32°C), which remains relatively stable throughout the year, to provide space heating, cooling and domestic hot water inside the building area. The purpose of this study, however, is to examine the means of reducing of energy consumption in buildings, identifying GSHPs as an environmental friendly technology able to provide efficient utilisation of energy in the buildings sector, promoting the use of GSHPs applications as an optimum means of heating and cooling, and presenting typical applications and recent advances of the DX GSHPs. It is concluded that the direct expansion of GSHP are extendable to more comprehensive applications combined with the ground heat exchanger in foundation piles and the seasonal thermal energy storage from solar thermal collectors. This study highlights the energy problem and the possible saving that can be achieved through the use of the GSHP systems. This article discusses the principle of the ground source energy, varieties of GSHPs, and various developments.

BiographyAbdeen Mustafa Omer (BSc, MSc, PhD) is an Associate Researcher at Energy Research Institute (ERI). He obtained both his PhD degree in the Built Environment and Master of Philosophy degree in Renewable Energy Technologies from the University of Nottingham. He is qualified Mechanical Engineer with a proven track record within the water industry and renewable energy technologies. He has been graduated from University of El Menoufia, Egypt, BSc in Mechanical Engineering. His previous experience involved being a member of the research team at the National Council for Research/Energy Research Institute in Sudan and working director of research and development for National Water Equipment Manufacturing Co. Ltd., Sudan. He has been listed in the book WHO’S WHO in the World 2005, 2006, 2007 and 2010. He has published over 300 papers in peer-reviewed journals, 200 review articles, 15 books and 150 chapters in books.

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Biological study of some first series transition metal complexes with adenine ligandHamad Mohamed Adress Hasan1, Aaza I Yahiya1, Safaa S Hassan2, Mabrouk M Salama3

1Omar Al Mukhtar University, Libya2Cairo University, Cairo, Egypt3University of Benghazi, Libya

Adenine complexes were prepared with some of the first series transition metals in a stoichiometric ratio of 1 : 2 ( Mn+: L), where Mn+ = Mn2+, Fe3+, Co2+, Ni2+, Cu2+, Zn2+, and Cd2+ ions. The Complexes were characterized by the physicochemical

and spectroscopic techniques as electric conductivity, metal contents, IR, UV–Visible, and molar conductance techniques. The stoichiometric ratios of the synthesized complexes were confirmed by using molar ratio method. The dissociation constant of adenine ligand was determined spectrophotometrically. Solvent effect on the electronic spectra of the adenine ligand was examined using solvents with different polarities. The biological activity of adenine ligand and its metal complexes were tested in vitro against some selected species of fungi and bacteria. The results showed a satisfactory spectrum against the tested organisms.

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Preparation of high loft electrically conductive activated carbon web from acrylic waste for EMI shielding applicationsM. Salman Naeem1, Saima Javed2, Zafar Javed1, Zuhaib Ahmad3, Abher Rasheed1, Babar Ramzan1

1National Textile University, Faisalabad, Pakistan2Punjab University Lahore, Pakistan3Technical University of Liberec, Czech Republic

Introduction: In recent years, research on electromagnetic interference (EMI) shielding materials has attracted significant attention due to increase in electromagnetic population from widespread applications of computer and telecommunication technologies [1, 2]. For eco-friendly advancements in EMI shielding effectiveness,the development of new light weight shielding materials havingstrong absorption and weak secondary reflection is necessary. This can be achieved by porous morphology, large specific surface area and higher electrical conductivity of shielding materials [3,4]. Although number of research studies focused on developmentof porous carbon based EMI shielding materials, the construction oflightweight structures with excellent EMI shielding properties bysimple and affordable method is still a big challenge. This workpresented the simple and novel method for preparation of porousand electrically conductive activated carbon nonwoven web fromacrylic fibrous wastes. The prepared activated carbon is advantageous over carbon made from other materials because of low cost,high density, better purity, and virtually dust-free nature of acrylicfibers [5].The activated carbon web was prepared by sequentialaction of carding, thermal bonding with bi-component fibers and physical activation of acrylicfibrous web in presence of air. The carbonization was performedunder the layer of charcoal at 800oC, 1000oC and 1200oC with the heating rate of 300oC h-1 and without any holding time. Further,electrical conductivity, EDX, X-ray diffraction, SEM, X-ray tomography and BET analysis was carried out to study the effect ofcarbonization temperature on physical and morphological properties of activated carbon web. At the end, the electromagneticshielding ability of the produced three webs was investigated with respect to change in carbonization temperature and thickness ofmaterial using two different measurement approaches (i.e. waveguide method and coaxial transmission line method).

Results and Discussion: The physical properties of acrylic fibrous and high loft activated carbonnonwoven webs were determined in terms of shrinkage, flexibilityand dusting tendency as can be seen from table 1. The techniques of X-ray diffraction (XRD) analysis, Energy dispersive x-ray (EDX) analysis and Scanning Electron Microscopy were performed for in depth analysis of high loft AC webs prepared at different temperature.Effect of carbonization temperature on physical properties of high loft AC web

Temperature (oC) Yield (%) Shrinkage Flexibility Dusting800 61.7 Good Good Good1000 57.6 Good Average Average1200 45 Average Poor Poor

The electrical conductivity and EMI shielding was found to increase as the temperature for carbonization was increased. The higher EMI shielding results came from AC web prepared at 1200 oC (around 70 dB) because at high temperature more parallel orientation of chains and high degree of crystallinity as can be seen from figure 1.

Fig 1. Effect of carbonization temperature on crystallinity of AC webs

The range for EMI shielding for activated carbon webs prepared at different temperatures can be seen from figure 2. The EMI shielding was checked at three different frequencies (600MHz, 1 GHz, and 1.5 GHz).

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Fig 2. Effect of frequency on EM shielding effectiveness of AC webs

Conclusion: The present study was focused on development of porous andelectrically conductive activated carbon based electromagneticshielding materials from acrylic fibrous wastes. The simple andnovel approach was employed to introduce absorption and reflection properties of electromagnetic radiations into the shieldingmaterials. This was achieved by physical activation of thermal bonded high loft nonwoven web of acrylic fibers.

BiographyMuhammad Salman Naeem had done his PhD from department of Material Engineering, Technical University of Liberec under the kind supervision of Professor Jiri Militky. The topic of his PhD work is ‘’Development of activated carbon web from acrylic fibrous waste’’. He has 11 impact factor publications, 10 book chapters and 17 international conferences. Currently he is working as Assistant Professor in National Textile University, Pakistan. He is involved in teaching activities since December 2009.

[email protected]

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Poster Presentations

NMS-01Title: Investigation on the optical thermometry using fluorescence intensity ratio in microcrystals Aihua Zhou, Nankai university, China

NMS-02Title: Lanthanide-doped upconversion microcrystals with luminescent properties of multicolor tuning and dual-mode emission for anti-counterfeitingDandan Ju, Nankai University, China

NMS-03Title: Effect of TiO2 coating method on adsorption of zeolite nanoparticles Taehwan Oh, Yeungnam University, South Korea

NMS-04Title: Ag-Pt bimetallic nanoparticles reduction catalysts: Effects of their metal alloying composition and h2 evolution studies Shalaka Varshney, Ariel University, Israel

NMS-05Title: Effect of γ-ray MWCNTs on electrical conductivity of a PET/graphite composite Younggon Son , Kongju National University, Republic of Korea

NMS-06Title: Astrocytes, a key gateway for ZrO2: Tb nanoparticles transmission through the blood–brain barrierMarcin Chodkowski, Warsaw University of Life Sciences, Poland

Posters- Day 02

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Investigation on the optical thermometry using fluorescence intensity ratio in microcrystalsAihua Zhou, Dandan Ju, Feng SongNankai university, China

Temperature is an important parameter in our daily life. However, some circumstances aren’t suitable for contacting temperature measurement such as volcanic, coal mines and high-voltage power stations. To our delight, the emission

intensities of adjacent energy levels can be thermally populated in different temperaturedue to the Boltzmann distribution. Thus, it can precisely show the temperature through detecting the fluorescence intensity ratio. In our previous experiments, the NaGdTiO4 and β-NaLuF4:Yb3+/Er3+microcorystalshave been obtained by the traditional solid-state reaction method and hydrothermal method to study the temperature sensing property, respectively. In NaGdTiO4:Yb3+/Tm3+experiment, the multi-ratios of the upconversion intensities increase linearly with temperature (100K-300K) provides us a simple and accurate temperature measurement method. Multi-ratios can be more accurate than using only one, allowing for self-referenced temperature determination. In addition, the NaLuF4microcorystals are also deeply studied. By introducing the 40% of Ca2+ ions, the upconversion luminescence intensities are obvious enhanced. The excellent upconversion luminescence is more suitable for temperature sensing, owing to the feasibility in the practical applications. The maximum sensitivity of β-NaLuF4:20Yb3+/2Er3+/40Ca2+ (mol%) is0.00040K-1at 120K under the excitation pump power 1W, indicating that the sample with Ca2+ has potential for application to temperature sensing.

BiographyAihua Zhou is still a doctoral candidate in nankai university. From 2014 to 2016, she works on the surface plasmon polariton enhanced quantum cutting for improvement of the conversion efficiency of the silicon-based solar cell. From 2016 to present, her research concentrates on optical temperature sensing of rare-earth ion dopedphosphors.

[email protected]

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Lanthanide-doped upconversion microcrystals with luminescent properties of multicolor tuning and dual-mode emission for anti-counterfeitingDandan Ju, Aihua Zhou, FengSongNankai University, China

Lanthanide-doped upconversion (UC) materials always attract wide attention due to their special anti-Stokesshifting, which allow emitting visible light under near-infrared (NIR) light excitation. The UC materials can be applied

inmany fields, including biomarkers, display, security printing, solar cells, photodynamics therapy (PDT),and temperature sensing. Among all the UC hosts, NaLnF4 (Ln=Y3+, Lu3+, Gd3+) hostsare considered as suitable materials for UC emission. However, the utilization of traditional UC materials is limited by theirlow luminescence efficiency and intractable emission color.

Distorting the symmetry of the crystal environment surrounding Ln3+ is an effective method of increasing UC luminescence intensity, and doping is a potential route to tailor the environment around Ln3+ ions. Simply tuning the co-doping concentration of ions with different valences (Li+ and Lu3+)could notonly modify the morphology and size of NaYF4:Er/Yb microcrystals but also enhance the emission intensity without changingthe phase of the host matrix, and meanwhile, both the excitation power density and pump wavelength are responsible for color-tuning properties of the bulk microcrystalswhich suffer from the insensitive response to excitation power before.The changing colors can be easily distinguished with naked eyes and multicolor emission of NaYF4:Er/Yb/Li/Lu would create an exciting possibility for easily visualizing anti-counterfeit pattern instead of complicated decoding setup.

Besides, we synthesized the uniform core-shell structured NaLnF4@-NaLnF4 microcrystals via the epitaxial growth technique. These microscale core-shellstructures provided a platform for the spatially confining optical process while possessing highluminescence efficiency.The uniform NaYF4@NaLnF4 microrods, with a series of rare-earth ions doped into the core and shell layer at various dopingconcentrations, achieved color-tuning of the upconversionemission and dual-mode emissionat the single-microcrystal level, makingthem ideal candidates in photovoltaic and anti-counterfeiting applications.

BiographyDandan Ju is a doctoral candidate of the Key Laboratory of Weak Light Nonlinear Photonics at Nankai University, China. Her research interest includes the synthesis, design and application of lanthanide-doped upconversionmicrocrystal, focusing on increasing the upconversionluminescence efficiency and achieving multicolor emission for practical application, such as photovoltaic, security purpose, etc.

[email protected]

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Effect of TiO2 coating method on adsorption of zeolite nanoparticlesTaehwan Oh1, Yujin Kim1, Hyemi Choi1, Kihoon Min2, Sungwon Park2, Dongsoo Shin3, and Gyusik Kim3

1Yeungnam University, South Korea2Sewon Tech, South Korea3Clavis, South Korea

Titanium dioxide (TiO2) was coated onto zeolite nanoparticles to enhance the heat stability of adsorbed functional materials into zeolite. The effect of synthesizing method and reaction conditions on adsorption and the heat

resistance of the materials was investigated. Titanium isoproxide (TTIP) was used as a precursor for TiO2. Reaction conditions such as reaction time and pH of the precursor solution were varied in this study. TiO2 coating methods were a separate stepwise reaction and a simultaneous reaction. The coating procedure was more effective than change in the reaction conditions. After absorbing the function material into the zeolite particles, they were melt compounded with poly(ethylene terephthalate) (PET) polymer.

Acknowledgement: This work was supported by the project of P0002868 and 217C000523.

BiographyTaehwan Oh has completed his PhD at the age of 28 years from Seoul National and has worked for Taekwang Industry and HUVIS from 1998 to 2008. He is a professor of Yeungnam University. He has published more than 20 papers in reputed journals and serving as an editorial board member of Korean Fiber Society

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Ag-Pt bimetallic nanoparticles reduction catalysts: Effects of their metal alloying composition and h2 evolution studiesShalaka Varshney1, Ronen Bar-Ziv2, Tomer Zidki11Ariel University, Israel 2Nuclear Research Center Negev, Israel

In the advancing field of nanotechnology, metallic nanoparticles (NPs) have gained a tremendous interest as heterogeneous catalysts and been well established as the subject of a wide research due to their promising use in catalysis.1-3 Herein, we

present a kinetic study of reduction reactions on Ag, Au, Pt metallic and Ag-Pt bimetallic alloy NPs that were synthesized in aqueous suspensions without using any stabilizer. Owing to the synergistic and alloying effects between the metals in Ag-Pt alloy NPs, those have shown superior catalytic performance in the reduction of 4-nitrophenol to 4-aminophenol by NaBH4. In the bulk, an alloy of Ag and Pt has not been observed because of the vast immiscibility of these metals, whereas in the nanosized regime, the prepared Ag-Pt alloy NPs have not only shown higher catalytic efficiency than their mono-metals but also eliminated the induction time which was observed in the pure Ag NPs case. Kinetics studies of hydrogen evolution on all NPs were conducted in order to follow the reduction mechanism of the fastest Ag-Pt catalyst. High-resolution transmission electron microscopy (HR-TEM) and X-Ray powder diffraction (XRD) studies show that the silver-rich Ag-Pt alloy NPs have a spherical linked shape and confirm the structure of an alloy with the size of ~4.0 nm. Ag-Pt alloy NPs are also relatively low-cost catalysts as their one particular metal ratio composition presented the highest catalytic activity with a relatively low content of Pt.

BiographyShalaka Varshney was born in Uttar Pradesh, India in 1993. She is a PhD student at the Department of Chemical Sciences, Ariel University, Ariel, Israel under the supervision of Dr.TomerZidki. She received her Dual Degree B.Tech and M.Tech in Nanotechnology from the University of Rajasthan, Jaipur, India in 2016.Her research currently focuses on the investigation of nano-catalytic reaction mechanismon the surface of nanoparticles. Her major interests are in the synthesis and characterization of metallic, bimetallic nanoparticles and different dimensional nanomaterialsand their self-assembly in discotic liquid crystals.

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Effect of γ-ray MWCNTs on electrical conductivity of a PET/graphite composite Younggon Son and TaehyunYoo Kongju National University, Republic of Korea

The effects of a compounding method and γ-ray treated multiwall carbon nanotubes (MWCNTs) on the electrical conductivity of graphite/PET composites were investigated.

We found that dispersion of MWCNTs in the PET phase plays a critical role in determining the electrical conductivity of graphite/PET/MWCNT composites. Dispersion and electrical conductivity were enhanced by a two-step method in which PET and MWCNTs are compounded in advance and the MWCNT/PET mixture is then compounded again with graphite. It was also observed that γ-ray treated MWCNTs provide enhanced conductivity in the graphite/PET/MWCNT composite. The synergetic effect of the two-step mixing method and γ-ray treatment made it possible to increase the conductivity of graphite/PET composites to a great extent with a very small amount of γ-ray irradiated MWCNTs.

BiographyYounggon Son has expertise in polymer processing and rheology. His special interests is development of small devices which compounds two different polymers with small quantity and measures the rheological properties with only several tens milligrams.

[email protected]

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Astrocytes, a key gateway for ZrO2: Tb nanoparticles transmission through the blood–brain barrierMarcin Chodkowski1, Anna Słońska-Zielonka1, Joanna Cymerys-Bulenda1, Jarosław Kaszewski2, Rafał Pietuszka2, Marek Godlewski2, Michał M Godlewski11Warsaw University of Life Sciences, Poland 2Polish Academy of Sciences, Poland

Nanoparticles (NPs) have been used in various commercial and medical applications. Considered possible applications of NPs in medicine include cancer therapy, cellular imaging and delivery of various molecules into cells. Recently, it was

suggested that NPs are able to permeate into the brain tissue and this translocation can happen by passing to the bloodstream and crossing the blood brain barrier (BBB). Our previous findings, for the first time show trafficking of the vesicles containing nanoparticles along the projections of the neurons in the culture of primary murine neurons. Following the lack of sufficient knowledge about the NPs in the nervous system, we aimed to investigate the mechanisms of the uptake, trafficking and toxicology issues of nanoparticles in astrocytes, one of the elements of the BBB.

For the experiment on primary murine astrocytes, non-toxic nanoparticles based on the zirconium oxide doped with 0.5%Tb (ZrO2:Tb) were used. Balb/c (H-2d) mice were used to establish primary culture ofmurine astrocytes. Concentration of 0.001 mg/ml of ZrO2:Tb in growth medium was added to the primary murineculture medium, and the interactions with actin cytoskeleton as well as mechanisms of endocytosis were investigated.

Introduction of ZrO2: Tb NPs into the culture of primary murine astrocytes did not induce toxicity, nor other adverse effects. We did not observed any changes in the structure of actin filaments at 3 and 24 h after administration of NPs. Moreover, co-localization of the nanoparticles and clathrin indicates that probably this pathway participates in endocytosis of NPs in astrocytes. Our findings confirm that the NPs enter the brain tissue by crossing the blood brain barrier. In conclusion, the ZrO2:Tb nanoparticles proved to be biocompatible and a valid tool to assess intracellular trafficking dynamics in the neurobiology.

Acknowledgments: The research was partially supported by the National Centre for Research grants “Maestro” 2012/06/A/ST7/00398, “Miniatura” DEC-2017/01/X/NZ3/00205and “Sonata-Bis” UMO 2012/05/E/NZ4/02994 supported by the grant from 05-1/KNOW2/2015 “Healthy Animal-Safe Food”.

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Nanotechnology and Material ScienceDecember 04-06, 2017 | Dubai

Proceedings of Global Summit on

Hosting Organization: Linkin Science649 Mission St., 5th Floor, San Francisco, CA 94105, USA

Ph: +1 (415) 463-8448 Fax: +1 (415) 463-8449Email: [email protected]

Exploring & Connecting Science


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Abstracts - Day 01


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Undoped and lithium doped zinc oxide thin films were deposited by electro deposition technique from aqueous solution onto ITO substrates at optimum conditions. The variations of the structural, electrical

and optical properties with the doping concentration were investigated. XRD analysis showed typical patterns of the hexagonal ZnO structure for both doped and undoped films. The films were polycrystalline with the (002) preferred orientation. No diffraction peaks of any other structure were found. The grain size and optical band gap were evaluated for different doping concentrations. The films with 5.10-6 M Lithium had a high crystallographic quality and a resistivity of 3,9.10-4 Ω. cm with an energy band gap of 3,3 eV.

It is very obvious that ZnO-Li films fabricated by sol-gel at optimum conditions are suitable for electronic applications, especially those requiring transparent electrodes.

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Electro deposition of Li- doped ZnO nanowire arrays for solar cellAhmed El HichouUniversité Cadi Ayyad, Morrocco


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Statement of the Problem: The most common chemotherapy regimens for treating cancer are based on the application of nonspecific cytotoxic substances which can induce toxic side effects. Targeted cancer

therapy is a powerful therapeutic strategy to management of cancer. HER2 as an anticancer target has long been studied. Its over expression plays an important role in the pathogenesis and progressiveness of breast and other cancers. Methodology & Theoretical Orientation to establish efficient and reliable drug delivery to HER2-overexpressing cells, the authors of this study have developed anti-HER2 (ErbB2) peptide-liposomal formulations of doxorubicin (DOX) by an engineered breast tumor targeting peptide ligand, AHNP, Anti-HER2/neu peptide, (FCDGFYACYADV) with three glycine amino acids as spacer before its original sequencing. Towards this goal, PEGylated liposome doxorubicin (PLD) bearing different ligand densities of AHNP was prepared and characterized for their size, zeta potential and peptide conjugation. The AHNP functionalization and density effects on breast tumor cell uptake, selective cytotoxicity, prevention of tumor growth and the tissue bio distribution of encapsulated DOX were studied in mice bearing TUBO breast cancer tumor model.

Findings: The findings demonstrated that increasing the ligand density of AHNP increases cytotoxicity and cell-uptake in SKBR3 and TUBO cells which over express HER2 but not in MDA-MB-231with low HER2 expression profile. The anticancer activity was also superior for targeted liposomal DOX with more AHNP densities. Conclusion & Significance: This experiment displayed the great potential of AHNP as a targeting moiety on the liposome surface and emphasized the significance of adjusting density of ligand to maximize the targeting capability of the nano drug delivery systems. Overall, the results showed that optimum AHNP density functionalization of PLD can significantly improve selectivity and the therapeutic index of liposomal DOX in the treatment of HER2 positive breast cancer and merits further investigation.

Biography Masoumeh Zahmatkeshan has her expertise in drug delivery and nanotechnology. Her open and contextual evaluation model creates new combination and optimization pathways for treatment of breast cancer. She has built this model after years of experience in research, evaluation and teaching both in research and education institutions. The foundation is based on fourth generation evaluation (Guba & Lincoln, 1989) which is a methodology that utilizes the previous generations of evaluation: measurement, description and judgment. It allows for value-pluralism. This approach is responsive to all stakeholders and has a different way of focusing.

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Improved drug delivery and therapeutic efficacy of PEgylated liposomal doxorubicin by targeting anti-HER2 peptide in murine breast tumor modelMasoumeh ZahmatkeshanIUMS, IRAN


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We have screened a diverse set of 12 metal-organic frameworks (MOFs) for iodine capture using a molecular modelling. The simulation results provide insights into the influence of pore volume and

surface area that influence the storage capacity. We have shown that MOFs with high pore volume and surface are preferred for iodine storage at ambient conditions of pressure and temperature, while at low pressure MOFs with smaller pore volume are more qualified for iodine capture. Moreover, some materials show very high adsorption capacity at normal conditions (13 g g−1), which is higher than any material capacity reported to date. Simulations also show that adsorption sites formed by the metal clusters are the preferential adsorption sites for iodine molecules. In order to increase the iodine capacity of MOF type materials, structures with high density of metal sites must be designed.

One MOFs (Cr-MIL-101) was prepared and investigated in detail to demonstrate the iodine removal efficiency and capacity of MOFs. Detailed material characterization analysis is presented for the MIL-101 loaded with I2. This includes powder X-ray diffraction (XRD), Infrared (IR), scanning electron microscopy coupled with energy-dispersive spectroscopy (SEM-EDS) and X-ray photoelectron spectroscopy (XPS). The typical sorption kinetics and uptake isotherms were measured using radioactive iodine (123I) for the first time. The results showed that MIL-101 has the same efficacy for capture of radioiodine 123I (96.61%) in comparing with active carbon (98%) but with much faster kinetics. Our results demonstrated that MOF scan be use as agent for radioiodine capture in hot cells and for nuclear accidents with radioiodine

Biography Bassem join Highest Institute For Applied Science and Technology (HIAST) in the Department of physics. He received diploma from HIAST in the field of Nuclear Engineering in 2002. He received a Master’s degree in Applied physics from Delft university of Technology in the Netherlands in 2006 and PhD. from Technical university of Dresden in Germany in 2011. In his thesis, he focused on Hydrogen storage in Nano-structured materials. His research focused on creating nanomaterials to pull radioactive ions from nuclear waste.

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Metal organic framework for radioactive nuclides capture and storageBassem AssfourAtomic Energy Commission of Syria, Syria


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Solar energy is a form of clean energy we received from the Sun, which can be harnessed using a range of technologies. It includes photovoltaics, solar thermal heating, artificial photo synthesis etc. An ideal

photovoltaic material is the one which helps in absorbing most of the radiation incident on it. In the present work, we have utilized copper oxide thin films and they were grown by a direct current magnetron sputtering technique. A 2 inch copper target of 99.99% purity was used as the sputter target and the depositions were carried by using argon as sputter gas and oxygen as reactive gas. All the depositions were carried out room temperature. The ratio of sputter and reactive gas during deposition was tuned to get the desired physical properties. We have studied the structural details and absorption behavior of the grown films. It was observed that the deposition conditions play a major role in obtaining a desired crystalline phase. The deposition conditions were optimized for achieving the cupric oxide phase, since they offer high absorption coefficient and desired electrical properties. Optical energy gap of the grown films obtained from the spectrophotometric studies was found to be 1.6 eV. Carrier type and the resistivity values of the films were obtained with the help of Hall effect measurements. Based on our results, we found that the films are suitable for solar energy applications.

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Copper oxide thin films grown by dc magnetron sputtering for solar cell applicationsDhananjaya KekudaManipal University, India


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This paper presents a modified design of Area-Efficient Low power Carry Select Adder (CSLA) Circuit.In digital adders, the speed of addition is limited by the time required to transmit a carry through the

adder. Carry select adder processors and systems. In digital adders, the speed of addition is limited by the time required to propagate a carry through the adder. The sum for each bit position in an elementary adder is generated sequentially only after the previous bit position has been summed and a carry propagated into the next position. The major speed limitation in any adder is in the production of carries.

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UV photodetector based on ZnO thin film nanostructureA. Pandey, Ravi Shankar, Anirudhh Bahadur YadavIndian Institute of Technology, India

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Statement of the Problem: Following the injury of nervous tissue, in particular, spinal cord injuries, axons do not regenerate appreciably in their native environment and current clinical approach to treating damaged

nerves is inefficient; thus, medical treatment approaches are needed. Neural tissue engineering research field has been progressed by using different approaches especially for repairing of damaged neural cells. In addition, it is known that electrical stimulation can be used for neurite growth and nerve regeneration.

Methodology and Theoretical Orientation in these study conductive properties of gold nanoparticles (GNPs, 39 nm) and their contribution to the enhancement of electrical stimulation to nerve cells have been conducted. In experimental section, polyethyleneimine (PEI) polymer coated cover glasses was used to create a positively charged glass surface and adsorption of GNPs was used in conjugation with this polymer coated substrate. Subsequently, PC12 cells were cultured on the modified glass surface and pulsed electric field of 1.5 V, 20 Hz was applied as electrical stimulation for 55 min duration.

Findings: Images from FESEM showed a uniform distribution of GNPs on glasses surface. In addition, enhanced neurite outgrowth (120 μm) using electrical stimulation was determined by inverted phase contrast microscopy images.

Conclusion and Significance: Finally, our study showed that pulsed current stimulation induced neurite outgrowth of PC12 cells adhered to the GNPs coated surfaces. Altogether, synergist combination of GNPs together with pulsed electrical stimulation can be used for enhanced nerve regeneration. Our future works will direct towards optimizing properties of NPs and stimulation parameters for in vivo nerve regeneration and do a comparative study with other nanomaterial including silk, carbon materials and etc.

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Investigating the effects of electrical stimulation via gold nanoparticles on in vitro neurite outgrowth: perspective to nerve regenerationMoein AdelIUMS, IRAN

Biography Moein Adel has his expertise in nerve regeneration and nanotechnology. His open and contextual evaluation model creates new combination and optimization pathways for treatment of CNS damages. He has built this model after years of experience in research, evaluation and teaching both in research and education institutions. The foundation is based on fourth generation evaluation (Guba and Lincoln, 1989) which is a methodology that utilizes the previous generations of evaluation: measurement, description and judgment. It allows for value-pluralism. This approach is responsive to all stakeholders and has a different way of focusing.


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In the present study, Pharmacophore Modeling, virtual screening and docking studies have been performed on a series of pyrimidinone derivatives against dipeptidyl peptidase IV. Pharmacophore Modeling study was

performed by creating hypotheses by identifying common pharmacophore hypotheses and analyzing hypotheses by enrichment factor. AHRR has been selected the final hypothesis with Phase Hypo Score 1.12 and ROC value of 0.98. ZINC database has been used for virtual screening of thousand of compounds based on validated pharmacophore against DPP-4. These screened compounds were further selected by Glide docking program via high throughput virtual screening (HTVS), standard precision (SP) and extra precision (XP) approaches against DPP-4 (PDB ID: 3GOG). Four top-ranked compounds ZINC34505198 (trelagliptin), ZINC14961096 (alogliptin), ZINC57344518 and ZINC57344513 were selected by virtual screening and docking studies. These compounds were showed better binding affinities towards DPP-4 by using amino acid residues such as TRY631, GLU206 and GLU285. The top-ranked compounds were showed their predicted binding energies with DPP-4 in the range of -9.646, -9.598, -9.18 and -8.915 kcal/mol, respectively. A comparative study of various DPP proteins such as DPP-8 and DPP-9 were also performed with ZINC derived compounds for detecting the binding pattern of active residues. DPP-8 showed binding energies -4.929, -4.627, -4.614, -.049 kcal/mol and DPP-9 showed binding energies -4.942, -3.019, -5.314, -5.598 kcal/mol with the four ZINC screened compounds. The results were concluded that compounds ZINC34505198, ZINC14961096, ZINC57344518 and ZINC57344513 identified as potential DPP-4 inhibitors that may be used as proposed compounds for further development of strong inhibitors.

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Pharmacophore modeling, virtual screening and docking study of pyrimidinone inhibitors of dipeptidyl peptidase IVVivek AsatiInstitute of Pharmaceutical Sciences, India


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The research area was in Gashua, Bade Local Government Area, Yobe State, Nigeria. The levels of fluoride, cadmium, arsenic, lead, iron and nickel were determined in sachet and borehole water samples. The

levels of fluoride, cadmium, arsenic, lead, iron and nickel were also determined in blood and urine samples with respect to age groups and gender. Sample collection and preparations were carried out using standard procedures. The concentrations of all the studied metals were determined using atomic absorption spectroscopy (A.A.S). The concentration of fluoride was observed to be higher in the male subjects when compared to the female subjects. It was also observed that the concentration of fluoride was significantly higher in the urine samples when compared to the blood samples. From the present study the concentration of iron ranged from 0.11 to 2.13 mg/L, 0.01 to 1.42 mg/L arsenic, 0.01 to 2.13 mg/L cadmium, 0.01 to 1.77 mg/L nickel and 0.02 to 2.13 mg/L lead. Results from the present study showed that the mean concentrations of arsenic in the borehole water samples from the different wards in Gashua ranged from 0.87 to 2.98 mg/L; 0.44 to 0.77 mg/L lead, 1.04 to 2.13 mg/L nickel, 0.12 to 0.35 mg/L cadmium and 2.56 to 5.56 mg/L iron. The values obtained from the borehole water samples were higher than the WHO standard value of 0.05 mg/L arsenic, 1.0 mg/L iron, 0.01 mg/L lead, 0.07 mg/L nickel and 0.005 mg/L cadmium for drinking water. Information from this research showed the possible factors that may result in gender metal accumulation. The concentrations of all the study metals in the urine and blood samples were significantly higher than the WHO limits. Data obtained from borehole water samples showed that, the borehole water might be a contributing factor to blood/urine metal accumulation. Information from this research also showed the possible factors that may result to higher concentrations of all the metals in urine (both recent and past exposure) when compared to blood (only recent exposure). Data obtained from the present research indicate that the concentrations of all the metals in the blood and urine samples increased with increase in age group. This fact could be explained by the tendency of heavy metals to accumulate in the human body (bioaccumulation of heavy metals) with time, indicating that metal accumulation is age dependent.

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Determination of fluoride and some heavy metals in water, blood and urine samples among some inhabitants of gashua, bade local government area, yobe state, nigeriaMusa Muhammad MahmudUniversity of Maiduguri, Nigeria


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Aerogels are nanostructured and open porous solids that are usually prepared in a first step by the traditional low-temperature sol-gel synthesis followed by the second step of drying at pressure and temperature higher

than the critical point of the pore fluid. Though Kistler performed the first synthesis of silica aerogel in 1931, it is generally assumed as recent discovery due to its relative obscurity until lately. These fragile materials are well known for their low density, porosity and high surface area. Off late, silica aerogels and modified aerogels have been widely employed as catalyst support and catalysts. Carbon catalyzes reactions and the advanced materials like carbon nano tubes can substitute conventional catalyst supports and are also capable of catalyzing reactions. Uzma Bangi et al. reported the successful incorporation of multiwalled carbon nanotubes (MWCNTs) into silica aerogels for improving the mechanical strength. But the capability and potential applications of such materials were never explored. This abstract briefs on our research involving preparation of MWCNT incorporated sodium silicate based aerogel by ambient pressure drying. The MWCNT/Silica aerogel sample was appropriately characterized. The XRD pattern and the N2-adsorption desorption experiments confirmed the characteristic porous aerogel; the SEM identified its morphology and the surface functional groups or modification are realized by FT-IR and Raman Spectroscopy which furthered our understanding of the surface and the organic compounds-solvent-solid interactions. The aerogel composite performs as a recyclable catalyst in multicomponent reaction and its another application demonstrates the decolourisation of Eriochrome Black T and Methylene Blue from their aqueous solutions. As far as highlighting the importance of the MWCNT/Silica Aerogel is concerned, it should be stressed that this research not only reports the aerogel composite in significant catalytic and environmental applications but also bears further scope in using this versatile aerogel nanocomposite in some interesting and feasible geoengineering applications by way of its coating on fabric and also by way of developing aerogel as a sky-ceiling. In addition to this, the composite material is found to fluoresces well and also helps us identify adsorption of volatile organics that are prevalent in comet dust and also the inter-stellar medium. Hence there is a good scope for developing this aerogel composite for storing organics and their spectroscopic detection. Though the aerogel tends to have high colour stability, this e.g. with rutile titania, is worth developing for UV inhibition purpose. Such new possibilities provide new proving grounds for the scientific fraternity in developing these functional materials for their use in a broad spectrum of applications including catalysis, adsorption, space suit, aerogel tiles for comet dust collector and other space exploration activities, etc.

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MWCNT reinforced silica aerogel by ambient pressure drying: preparation, characterisation and applicationsIsak Rajjak ShaikhSwami Ramanand Teerth Marathwada University, India


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Keynote - Day 02


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Silicene is the Si analogue of graphene with the same honeycomb structure and linear dispersions of the π and π* bands at the K point of the Brillouin zone. It is predicted to realize a buckled structure, due to

sp2-sp3 hybridization, and is compatible with the current Si-based nano-electronics. Silicene yet has not been achieved by mechanical exfoliation but can be deposited on metallic substrates such as Ag(111), Ir(111), and ZrB2(0001). Regrettably, strong interaction to these substrates destroys the Dirac physics. For this reason, semiconducting substrates, including Si(111) and SiC(0001), have been explored theoretically to evaluate whether they lead to a Dirac cone with reasonable band gap (which is essential for applications). However, surface passivation is inevitable for these and similar substrates, due to their dangling bonds. Layered materials such as MgBr2(0001), MoX2, and GaX2 (X = S, Se, and Te), on the other hand, might preserve the characteristic electronic states of silicene and additionally simplify the preparation procedure as passivation is not required. The predicted effects of different substrates on silicene will be compared and evaluated with respect to technological requirements.

Biography Udo Schwingenschlögl is a Professor of Materials Science & Engineering at King Abdullah University of Science and Technology (KAUST), Saudi Arabia. He previously worked at the International Center of Condensed Matter Physics in Brasilia, Brazil, and the University of Augsburg, Germany. His research interests in condensed matter physics and first-principles materials modeling focus on 2D materials, interface and defect physics, correlated materials, thermoelectric materials, metal-ion batteries, nanoparticles, and quantum transport.

[email protected]

Notes:

Substrate effects on silicene and how to exploit them

Udo SchwingenschlöglKing Abdullah University of Science and Technology, Saudi Arabia


Global Summit on

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Fibers like M5, PBO, Spectra, and Kevlar are used in high impact applications. Although these fibers have high strength and modulus, their fracture strain is low which leads to moderate energy absorption. Normalized

velocity for M5, PBO, Spectra, and Kevlar are currently at 1000, 837, 887, and 680 m/sec, respectively. Normalized velocity is a combined measure of fiber’s toughness and tensile wave speed, which is essentially the total energy absorption by the fiber. The question is – whether this energy absorption can be doubled or tripled for extreme loading events. Such high energy absorption is possible through a transformative change in the structure of the fiber. It has been shown that such structural change can be made through a hybridized polymer blend and infusion of carbon nanotubes.

A case in point is ultrahigh molecular weight polyethylene (UHMWPE) and nylon. Fracture strain of nylon is one order higher than that of UHMWPE while its strength and modulus are one order lower. Blending of the two increases fracture strain of UHMWPE to an intermediate level. On the other hand, dispersed nanotubes get aligned during the drawing process, co-continuously deform and carry the load resulting in higher strength and modulus. Net effect therefore leads to higher energy absorption. From a quantum energy concept, both polyethylene and polyamides have small cluster of atoms, allowing an opportunity to exchange molecular features if blended. Polymer (blended) crystallinity, strength, and modulus otherwise lost in the blending process, can be fully recovered and enhanced further with the inclusion of nanotubes.

The presentation will delve into scientific inquiries to understand interplay at the interface of major and minor phases, role of compatibilizer, deformation of the dispersed phase, formation of chemical bridges, interfacial tension, and role of nanotubes in sharing load and developing crystallinity.

Biography Hassan Mahfuz is the Director of Nanocomposites Laboratory and Associate Dean for Research, College of Engineering and Computer Science. His research interests are Computational Methods in Solid Mechanics, Finite Element Method, Polymers, Polymer Composites, Polymeric Fibers, Composites Manufacturing, Mechanics of Composites, Nanomaterials, Nanocomposites, Experimental Stress Analysis, Machine Design, and Computer Aided Design.

[email protected]

Notes:

Structure formation in high performance fibers with polymer blends and nanotubes for extreme loading events

Hassan MahfuzTuskegee University, USA


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Nanomaterial-based solar cells attract people’s attention for its clean and renewable properties. One-dimensional nanostructures can provide attractive architectures for solar energy applications, not only

because of the unique physical properties that can be seen from the nanometer-scale structures but because of geometrical impacts that affect the performance of solar cells. Copper (Cu)-Indium (In)-Gallium (Ga)-Selenide (Se) CIGS nanowires are promising materials for solar cell applications due to the large light abortion coefficient (around ~105 cm−1), and wide adjustable bandgap range (1.04 to 1.72 eV). We present a feasible approach for fabrication of CuIn(1−x) GaxSe2 (CIGS) nanowire based solar cell by taking advantage of size-effect which increase the effective pn junction size per cell. This electrochemistry-based process includes one-step electro deposition technique to grow CIGS nanowires into the porous anodized aluminum oxide (AAO) template, which is a cost-effective alternative process to vacuum-based deposition process. Composition of CIGS nanowires, determined by energy dispersive spectroscopy (EDS), was achieved through a manipulation of the applied potential and composition of electrolytes. X-ray diffraction analysis showed that crystallinity of CIGS nanowires were improved by annealing. We fabricated the solar cell structure by etching AAO structure after growing highly ordered vertical array of CIGS nanowires as p-type. Chemical bath deposition was followed to deposit a smooth CdS layer as n-type, thin-film of PEDOT: PSS was deposited by spin coating as top layer to act as a transparent and conductive layer.

Biography Daniel Choi received his B.S. in Metallurgical Engineering from Seoul National University (South Korea) and PhD in Electrical Engineering from UCLA. Dr. Choi was a staff member for three years at the Aerospace Corporation and a task manager Jet Propulsion Laboratory (JPL)/NASA for nine years, leading a number of space-related projects such as Phoenix and Mars Science Laboratory project. He was an associate professor and director of the Materials Science and Engineering (MSE) program at University of Idaho (USA). Currently, he is Founding Department Head of the Mechanical and Materials Engineering in the Masdar Institute of Science and Technology, Abu Dhabi, UAE. He is also a Science Team for UAE Emirates Mars Mission Program.

[email protected]

Fabrication of CIGS nanowires based on electro deposition for photovoltaic applications

Daniel S. ChoiMasdar Institute of Science and Technology, UAE

Notes:


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Abstracts - Day 02


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Biogenic synthesis of superparamagnetic Fe3O4 nanoparticles with specific sizes and shapes have been a challenge in biomaterial science. Synthesis using plant compounds has remarkable advantages in

pharmacology to cure various diseases due to higher efficacy and less toxicity of the plant phytochemicals that attach to the NPs. The well developed surface chemistry of Fe3O4 makes it easy to load them with biopharmaceutics, promoting them as nanoplatforms for building up nanoparticle-based theranostics. These phytochemical-loaded magnetic nanosystems permit a slow, sustained & controlled release of the encapsulated plant compounds at the target site. This paper describes the fabrication of monodispersed superparamagnetic Fe3O4 conjugates by using phytochemical extracts of the medicinal plant Simarouba Glauca (Laxmi Taru) having anticancer properties. These Fe3O4-Lax nanocomposites are then functionalised with essential oils Eugenol & Ylang Ylang by surface coating methods. These essential oils are known to be powerful anticancer, anti-inflammatory, antioxidant agents. The nanoencapsulation of Eugenol & Ylang Ylang on polymeric Fe3O4 improves their solubility and bioavailability, prevents photo-oxidation, decreases volatility and enhances their antimicrobial and therapeutic efficiency. Various techniques used for confirming the formation of the Fe3O4

conjugates were XRD, FTIR, VSM, SEM, TEM and DLS methods. The amount of Essential Oils loaded on Fe3O4 nanoparticles was measured as Entrapment Efficiency values using UV-Vis spectroscopy. The antibacterial activity was tested on the bacteriums S. Aureus & E. Coli. The compounds showed synergistic antioxidant activity which was measured using DPPH assay. The study showed that Fe3O4-Lax- Eugenol/Ylang phytohybrids are efficient for stabilising and controlling the release of these essential oils thereby maximising their biological activity. All compounds used for synthesis are of natural plant origin with no side effects and thus these phytohybrid nanosystems can be used as a strategy for therapeutic approach in Nanomedicine such as cancer therapy, magneto aerosols, anti-biofilm and anti-Infection therapy.

Notes:

Biogenic synthesis of Fe3O4-conjugates using medicinal plant extracts of Simarouba Glauca and functionalized with essential oils for applications in NanomedicineJanesline P.D. FernandesSt. Xavier’s College, India

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Biography Janesline P. D. Fernandes has an excellent academic record with O+ Grade in M.Sc (Inorganic Chemistry) and a M. Phil. Degree to her credits. She is currently an Associate Professor in Chemsitry, St. Xavier’s College, Goa, India. Her research interests are in synthetic strategies and functionalization of nanomaterials for drug delivery and biomedicine. She has guided several projects in the field of Nanochemistry and has presented her research papers at conferences / seminars and earned appreciations in the State of Goa and outside. She has won several awards in the first place category for her oral and poster paper presentations at various events. In December 2016, she has received the International Best Oral Paper Presentation Award at the International Science Congress 2016, Pune-India. She has also earned great reviews for her teachings and student motivation and was honored with Best Educationist Award in June 2017. She is a friendly person, loves travelling and has a happy and a positive approach towards life.


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In recent years, investigations on the photocatalytic application of TiO2 and its composite materials are intriguing interest, due to the small crystal size, high specific surface area and highly porous structure

of mesoporous titanium dioxide. However, the most drawbacks of TiO2 are its large band gap and massive recombination of photogenerated charge carriers, which make the catalytic efficiency low. Thus, modification of the electronic band structure of TiO2 by noble metal deposition and co-doping with two or more foreign ions have been attracted much attention to overcome the large band gap of TiO2.

In this research, we demonstrated a facile co-doping approach to synthesize of gold-preyssler-titanium dioxide nanocomposite, as a new and green photocatalyst. We synthesized this nanocomposite and characterized by UV-vis spectroscopy, X-ray diffraction (XRD), Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM). In addition, the photo degradation of Malachite Green as a pollutant azo dye, in a designed photo reactor in our laboratory was performed as a test reaction to estimate the catalytic activity of this nanocomposite. The obtained results showed that malachite green solution can be degraded under UV light in the presence of the synthesized nanocomposite. For a systematic comparison, the photocatalytic activity was performed with classical catalyst: TiO2. In all cases, maximum of photodegradation was observed by using gold-Preyssler-titanium dioxide nanocomposite as catalyst. The remarkable degradation of malachite green in the presence of this nano catalyst indicates that the treatments of other organic pollutants could be performed in the presence of this catalyst, in order to obtain a perfect photodegradation degree. This catalytic activity can also be extended to the other catalytic reactions.

Notes:

Synthesis and characterization of gold-preyssler-Titanium dioxide nanocomposite: A new and recyclable catalyst for photodegradation of malachite greenMoghaddam JafariaIslamic Azad University, Iran

[email protected]

Biography Moghaddam Jafaria got bachelor of Applied chemistry from Ferdowsi University of Mashhad and my master degree of inorganic chemistry from Azad university of Mashhad. She could achieve the highest GPA (3.9/4) among 60 graduate students of Inorganic chemistry Program. She worked at the water and sewer company of Mashhad as a researcher in 2010 after that she worked as research assistant in department of chemistry in the Azad University of Mashhad during her masters from 2011 to 2013. Her primary research interests are in the field of inorganic chemistry and Nanotechnology. Specifically, she is interested in produce metal Nano particles and their application in drug delivery, Nano photo catalysis and semiconductors and their application in medicine and environment. In her free time, she does kickboxing and track and field and plays piano.


Global Summit on

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Notes:

Spatial arrangement and precise positoning of 1D nanomaterials and scaling is one of the key factor for advanced electronics and photonics over two decades. The various lithographic methods, optic

lithography, electron beam lithography, interference lithography, zone-plate array lithography, focused ion beam lithography has been used for nanoarray formation. The applied lithographic methods are able to obtain nanoarray formation for the sub-100 nm features sizes, but these are not possible to produce large are dimension. Moreover morphological structures and chemical properties in the nanoscaled components may lead to complexity properties that are completely turned complex nanostructures. The controlled chemical segmentation of nanoarrays is required more controlled dimensions. To fabricate in small, desirable and scalable dimension on electronic industry, block copolymer lithography which present with a promising future in electronic industry due to their ability to self-organize at nanometer scales. Of particular importance is that BCP lithography is generally known to be capable of large-scale fabrication combined with hard mask techniques to create surfaces and selected area deposition.

In this perspective, block copolymer nanopatterning techniques for development and pre-development with graphene patterns were studied, the procedures for obtaining nanopatterns, the recent advances in the chemical and physical aspects of self-organized morphologies, nano-enabled surfaces or membranes and controlled self-assembled nanostructures will be presented.

Controlled dimensions using Block copolymers for various applicationsErsoz MSelcuk University, Turkey

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Biography Mustafa Ersoz is as Professor of Physical Chemistry in the department of chemistry, Faculty of Science, Selcuk University, Turkey. He is founder and served as director of Advanced Technology Research and Application Center of Selcuk University between 2005-2017. He is vice chair of European Cooperation of Science and Technology and principal member of the Turkish Academy of Sciences (TUBA). He coordinated the “Nanomaterials and Nanotechnologies” European cluster, is a member of the “Metals and Related Substances in Drinking Water” specialist group, IWA. He received the “Junior Scientists award” in natural sciences from TUBİTAK, The Scientific and Technical Research Council of Turkey. He received his Ph.D. scholarship in UK, NATO-ASI post doctorate fellowship and Leverhulme Trust visiting scientist fellowship in UK. He has been involved H2020 (MSCA-RISE) and FP7 projects (LAMAND, Chito Claen, EU-SOLARIS, Ligno Food) and core-STSM-MC member for COST CM1101, COSTMP1106, COST 637 and MC member COSTD43, COST D36, projects. Specifically, his research interests are nanochemistry, self-assembly, patterning-functionalisation, nanoparticles, electrochemistry at interfaces and membrane technology.


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Notes:

Liver diseases such as viral hepatitis, cirrhosis and hepatocellular carcinoma, are common in clinical practice with high morbidity and mortality worldwide. Hepatocyte selective imaging contrast agents can provide

useful information for evaluating hepatic function non-invasively in vivo. Recently, superparamagnetic iron oxide nanocrystals (SPIONs) have been widely explored as magnetic resonance imaging (MRI) contrast agents in biomedical research. The mannose receptor is a transmembrane protein expressed on the surface of macrophages, including Kupffer cells and endothelial cells. We aimed to target these receptors for MRI imaging of liver. Oleic acid coated SPIONs were developed with high crystallinity and magnetization by modified thermal decomposition method. The SPIONs were further made water soluble by ligand exchange with (3-aminopropyl) triethoxysilane (APTS). The size of APTS coated SPIONs was fond to be 9.5 nm. These hydrophilic SPIONs were encapsulated in albumin nanoparticles and further mannosylated by schiff base formation in acetate buffer pH 4. The mannose conjugation was confirmed by decrease in free amino groups on nanoparticles with TNBS assay. The MnBSA-SPIONs were characterized by DLS, TEM, SEM, XRD, AAS etc. The uptake of MnBSA-SPIONs was monitored in J774 cell line by prussian blue staining at different time intervals. The biocompatibility of MnBSA-SPIONs was tested in J774 cell line by MTT assay and was found to be biocompatible. The T2 relaxivity of nanoparticles was determined in phan-tom agar gels and was found to be 394 mM-1S-1. The in vivo MRI for liver imaging is currently underway.

Development and evaluation of mannose decorated bovine serum albumin coated superparamagnetic iron oxide nanoparticles (MnBSA-SPIONs) for liver imagingChetan NehateIndian Institute of Technology, India

[email protected]


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Abstracts - Day 03


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Notes:

The copper tin sulfideCu2SnS3 (CTS) is a p-type direct band gap material; its elements are non-toxic and earth-abundant. It can be used in photo thermal conversion of solar energy and as selective radiation filters

on architectural windows. The CTS compound was synthesized by solid state reaction method. The influence of soaking time on the structural and morphological properties of these films is investigated. X-Ray diffraction analysis of these compounds prepared with varying the soaking time at 900°C are found to exhibit tetragonal CTS phase with preferred orientation (1 1 2), (2 2 0) and (3 1 2). The XRD pattern showed that prepared samples do not contain any secondary phases. The grain size calculated using Debye-Scherer’s formula was found to be in the range of 34 nm-46 nm. The chemical composition of the compound estimated using Energy dispersive spectroscopy showed Cu/Sn atomic ratio in the range 0.9 to 1.10.

Influence of thermal processing rate on the structural and morphological properties of Cu2SnS3 (CTS) prepared using solid state reaction techniqueRaviprakash Y Manipal University, India

[email protected]


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Notes:

Diabetes mellitus is a worldwide public health problem, in 2000 WHO has been reported that at least 171 million people worldwide suffer from diabetes. The metabolic disorder could be reflected by the

variations of the glucose concentration from the normal range (4.4–6.6 mM). Therefore, the determination of glucose concentration is a very important issue in clinic for diagnosing diabetics. Numerous studies have been performed towards developing a real-time, quantitative, and biocompatible glucose biosensor. Several electrochemical techniques based on glucose oxidase enzyme were used successfully for oxidation of glucose. However, these indirect detection methods are disadvantaged because this enzyme needs to be replenished limiting the lifetime of the sensor. Moreover, developed of non-invasive measurement of blood glucose by various methods including optical spectroscopy techniques have remained an elusive target for more than two decades. Here, we demonstrated a simple, rapid and inexpensive fabrication method to develop gold nanostructures/graphene nanosheets modified ITO substrate and its application as a glucose enzyme-free optical biosensor with high sensitivity and selectivity. This Au nano dots/graphene modified ITO substrate was developed based on electrochemical deposition of Au and graphene onto ITO substrate layer-by-layer. This modified transparent substrate was successfully used to measure glucose concentrations within range from 500 nM to 10 mM by surface enhanced Raman spectroscopy. Moreover, the need to achieve accurate non-invasive measurements of glucose under the presence of other possible blood analytes leads us to apply this substrate to monitoring the glucose level in the presence of human serum. Our results demonstrated an efficient direct measurement of near-physiological level of glucose. The optimization of such system will open the possibility of using this modified substrate as an optical biosensor for the in-vivo, non-invasive and on-line monitoring of glucose.

Gold Nanostructures/Graphene nanosheets modified ITO substrate for enhance Non-enzymatic Detection of Glucose in Serum based on Surface-Enhanced Raman SpectroscopyWaleed Ahmed El-Said Assiut University, Egypt

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Poster Abstracts


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Notes:

A variety of novel quinoline derivatives (6-phenyl-6H-chromeno [4,3-b] quinoline) have been prepared by using 4-chloro-2-phenyl-2H-chromene-3-carbaldehyde and various substitutes of aromatic anilines

as starting materials. This is the first example on the preparation of quinolines through this novel method. And the resulting quinoline derivatives further structure evolution may leads to an anti cancer agents. Our preliminary data of model compound (7i) on three cancer cell lines (B16F10, MCF7 and A549) suggested decent anticancer activity on two cell lines (B16F10 and MCF7) with IC50 values of 14.8 and 21.32 µM, respectively. This method may require simple operation and works with a variety of substrates.

Catalyst-free synthesis of Novel 6-phenyl-6H-chromeno [4, 3-b] quinoline derivatives at RT: Their further structure evaluation leads to potential anti-cancer agentsRathod Aravind KumarCSIR-Indian Institute of Chemical Technology, India

[email protected]


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Notes:

STGF-β. Microemulsions are transparent, thermodynamically stable and isotropicfluid mixtures of oil, water and surfactant, frequently in combination with a co-surfactant. In contrast to emulsions, microemulsions

form upon simple mixing of the components and generally do not require high shear conditions used for emulsion formation. In this study, microemulsion systems were prepared using different surfactant, co-surfactant and oil ingredients. Among the ingredients tested were Tween® 20 and Tween® 80 as surfactants, PEG 400, glycerole, 2-propranol and isopropyl alcohol as co-surfactants and soybean and linseed oils. Microemulsions were prepared using pseudo-ternary phase diagrams. Optimum formulation was selected and characterized by droplet size, electrical conductivity, zeta potential and pH measurements.

A New Microemulsion Formulation for an Oil-Soluble DrugKemal Can DemirkilincAnadolu University, Turkey

[email protected]


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Notes:

The first material utilized for industrial fabrication of membranes is Cellulose acetate (CA). This polymer is a cheap material used in the membrane field, and has a good selectivity for the separation of CO2 from N2;

but its low permeability is a weakness. On the other hand, cellulose nanowhisker (CNW) has characteristics such as high crystalinity and polar functional groups on its surface that can improve the useful features of the polymeric membranes. The precursor of CNW is cellulose, a cheap material widely found in nature. We used cotton (a cellulosic material) as the precursor of CNW in the research. Permeability and selectivity of CA nanocomposite membranes were investigated at a pressure of 2 bar and three different concentrations of the Tosylated-CNW (To-CNW) which were 0.25, 0.5 and 1 wt% of nanocomposite. Solution-casting method was used to prepare the membranes and the concentration of the solid material (CA together with To-CNW) in the solvent (THF) was 11.2 wt%. The cast films were allowed to be dried at ambient conditions then in a vacuum oven for two days. Afterward the dense nanocomposite membranes were cut in the circle shapes and placed in the cell of the “pure gas set-up”. The results indicated useful features of the nanocomposite membranes have been improved using To-CNW derived from acidic hydrolysis and tosylation process. The effect of To-CNW content on permeability and selectivity of the prepared membranes is interpreted based on the influence of To-CNW on the CA chain packing because of good interaction between To-CNW and CA polymer matrix. The good interaction is related to existence of polar groups such as hydroxyls and tosyle esters on the surface of To-CNW and, hydroxyl and acetate groups on the CA polymer chains. Disrupting CA polymer chains leads to facilitate the diffusion of penetrants and consequently, increase in permeability. The most permeability and selectivity of penetrants were observed at 1wt% and 0.5wt% To-CNW. The polar groups on the surface of To-CNW, tosyle esters and hydroxyls, interact with the polar gas, CO2, and as a result, CO2 has more improved permeability thanN2, especially at 0.5wt%. Therefore incorporation of To-CNW into the CA matrix leads to enhancement in CO2/N2 selectivity which is maximum at 1% of nanocomposite without a clear drop in selectivity. It should be mentioned that the plasticization effect of CO2 on the membrane shouldn’t be ignored, a phenomenon which is observed due toCO2 permeability increment versus increased pressure in all prepared membranes.

Improved permeability and selectivity in the cellulose acetate membranes by tosylated cellulose nanowhiskersSaman SalimiLorestan University, Iran

[email protected]

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