name circle one: a1 a2 score /16
TRANSCRIPT
NAME_______________________________________
CircleOne:A1A2
SCORE_____________/16MULTIPLECHOICECirclethebestanswerforquestions1-10(1pteach)1. ApieceofdoublestrandedDNAhas30%A,whatwillbethe%ofG?
a. 30%b. 40%c. 20%d. 70%e. notenoughinformationtoanswer
2. YouhaveapieceofDNAwiththesequenceATGC.Fromthisyouknow,
a. Aisatthe5’endb. Aisatthe3’endc. Acouldbeateitherthe5’endorthe3’endofDNAd. Youhaveapalindromicsequencee. Noneoftheabove
3. Whichofthefollowingbasespairswithguanine?
a. Adenineb. Guaninec. Cytosined. Uracile. Thymine
4. Thenitrogenousbaseislinkedtotheriboseordeoxyribosesugarviaa
a. Glycosidicbondb. Amidebondc. Hydrogenbondd. Phosphoanhydridebonde. Phosphodiesterbond
5. GenomicDNAis_______resultingintheproductionof_______.
a. TranscribedmRNAb. Translated,tRNAc. Transcribed,DNAd. Translated,proteine. Replicated,mRNA
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6. _______istheadaptorthatiskeytoconvertingthetripletcodonsofmRNAintotheproteinpolymers.
a. tRNAb. rRNAc. mRNAd. siRNAe. lcRNA
7. Whichofthefollowingstatementsaboutdouble-strandedDNAisfalse?
a. Thebackbonecontainsalternatingdeoxyribosesugarandphosphategroups.b. Thetwostrandshaveanantiparallelorientation.c. Thehelixhastwogroovescalledthemajorgrooveandtheminorgroove.d. Thebasesareontheoutsideofthehelix.e. Thestrandsareformedbynucleotideslinkedtogetherviaphosphodiester
bonds.
8. Inthepicturebelow,arrowlabeled1correspondsto______andarrow2correspondsto_________.
a. Replication,transcriptionb. Translation,transcriptionc. Mutation,replicationd. Transcription,replicatione. Transcription,translation
9. Inthepicturebelow,whichlabel(s)ontheleftrefertothetemplatestrand?a. 1b. 2c. mRNAd. both1and2aretemplatestrandse. both1andmRNAarethetemplatestrands
10. WhichofthefollowingstatementsareTRUE?
a. ThemRNAistranslatedfrom5’tothe3’endb. ThemRNAistranslatedfrom3’to5’endc. Duringtranscription,themRNAissynthesizedinthe3’à5’directiond. AandCarebothtruee. BandCarebothtrue
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SHORTANSWER.Followdirectionswitheachquestion.11. Forthebasepairshownbelow,answerthefollowingquestions.(6pts)
a. Shownaboveis(circleallthatapply).
Adenosine Guanosine Cytidine Uridine Thymidine
b. Drawhydrogenbondsbetweenthebasesasdashedordottedlines.c. Ifpresent,CIRCLEthegroupthatisthemajordifferencebetweenuridineand
thymine.d. Drawanarrowtotheglycosidiclinkageofthepurine.e. Drawasquarearoundthe5’-carbonofthepyrimidine.
12. ThefollowingpieceofdoublestrandedDNAencodesaveryshortpeptide.Inthespace
below,writethesequenceofmRNAthatwouldbesynthesizedbyRNApolymerasefromthispieceofDNAifthebottomstrandisthetemplate.Thenwritetheproteinsequenceinone-lettercodethatwouldbesynthesizedbytheribosomefromthemRNAyoutranscribedusingthefirstreadingframe(useGeneticCodeTablebelow).Labelthe5’and3’endsaswellastheN-terminusandC-terminus.(4pts)5’- ATGGCTGGGATTTGCTAA-3’ 3’ –TACCGACCCTAAACGATT-5’mRNAsequence:5’-AUG GCU GGG AUU UGC UAA-3’Proteinsequence:N-term-MAGIC-Cterm
N
NN
N
NH2
O
HO
HH
HH
O
O
H O
H H
H H
O
N
HN
O
O