myocardial ischaemia national audit project are we replacing good fibrinolytic treatment with poor...
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![Page 1: Myocardial Ischaemia National Audit Project Are we replacing good fibrinolytic treatment with poor primary PCI? John Birkhead who has NO CONFLICT OF INTEREST](https://reader035.vdocuments.site/reader035/viewer/2022070402/56649f225503460f94c3aea2/html5/thumbnails/1.jpg)
MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject
Are we replacing good fibrinolytic treatment with poor primary PCI?
John Birkhead
who has NO CONFLICT OF INTEREST
ADVANCED CARDIOVASCULAR INTERVENTION 2010
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MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject
Primary PCI ; dominant reperfusion therapy in England & Wales
%
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MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject
Access to pPCI by hospital Q1 – 2 2009
93
No pPCI 100% pPCI
Hospitals in E&W; n = 223
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MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject
30 day mortality (95% CI): thrombolytic treatment and primary angioplasty for STE MI
9.5%
4.5%
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MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject
Use of thrombolytic treatment 2007-9
For admission diagnosis STE MI:
• >70 % had lysis < 60 min after call
• 28% pre-hospital (2007)
• door to needle 19 min (IQR 13, 26)
• >80% had lysis (2003-4)
• >60% had angio (2009)
Interval from onset of symptoms to treatment;~ admission diagnosis STE MI
Median 130 min
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MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject
30 day mortality; lysis & early angio or rescue vs pPCI
MINAP 2007-9
5%
4.4%4
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MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject
Median delays in provision of pPCI
Onset – needle 147 minutes193 min
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MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject
MINAP data
Reperfusion Rx for STEMI (England & Wales) 2003-9
33% too late16% ECG ineligible17% elective11% bleeding risk0.5% hypertension
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MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject
Distribution by ageband of reperfusion treatment2007-9
MINAP data
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MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject
Comparative use of reperfusion treatment by ageband 2007-9
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MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject
30 day mortality following lysis + rescue/early angio vs pPCI
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MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject
Are we replacing good fibrinolytic treatment with poor primary PCI?
Conclusions
Organisation: ?+Equity of access ? -
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MMyocardialyocardialIIschaemiaschaemiaNNationalational AAudituditPProjectroject