mrc/ucl centre for virology division of infection and immunity · 2018-04-07 · annegret pelchen...
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MRC/UCL Centre for Virology Division of Infection and Immunity
What is Science?
MRC/UCL Centre for Virology Division of Infection and Immunity
Virology
Viruses
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Viruses
Have you had!
Chicken Pox
Viruses
Have you had!
Herpes simplex
Viruses
Have you had!
Foot and Mouth
Three Broken Tulips (Nicolas Robert 1624-1685) Fitzwilliam museum, Cambridge
~10 viruses in the ocean 30
> 5,000 different viruses in 100 ml of seawater,
40 million viruses in one cubic metre of air
Electron Microscope
Electron Microscope Specimen Grid, 3 mm
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
890x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
1,200x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
5 !m
2,900x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
2 !m
4,800x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
2 !m
6,800x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
1 !m
11,000x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
1 !m
23,000x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
200 nm
49,000x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
200 nm
68,000x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
100 nm
98,000x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
100 nm
120,000x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
100 nm
150,000x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
100 nm
150,000x
Annegret Pelchen Matthews MRC Laboratory for Molecular Cell Biology
FMDV
Variola
Adeno
TMV
Ebola
All images from ICTV dB at http://phene.cpmc.columbia.edu/index.htm
Mimi
Phage T4
100nm HIV
Sneeze demo
H N H N H N
Reassortment of Influenza
H N H N H N
Reassortment of Influenza
H N H N H N
H N
Reassortment of Influenza
Reassortment demo
Virus Spread Demo
Viruses
Have you had!
BIOHAZARD
Ebola
BSL-4
Viruses
Have you had!
Small Pox
Ali Maow Maalim
October 1977 the last person on Earth to catch smallpox by natural transmission.
How do we prevent virus diseases?
Y
Y
Y Y
Y
Y
Antibodies Killer cells
Y Y
Y Y
Y Y
Antibodies Killer cells
Y Y
Y Y
Y Y
Antibodies Killer cells
Viruses are Small What about Big Pathogens?
Thanks for coming
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