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MRC Centre for Transplantation Bridging Fellowship

Division of Transplantation Immunology & Mucosal

Biology

School of Medicine

Application procedure

Should you wish to apply for this position, please send the following:

• Completed application form

• a copy of a current curriculum vitae, which should include inter alia:

o your full name with title

o details of your present post with date of appointment

o education

� degrees (subject, class, instit

� other academic/professional qualifications (subject, level, institution, date of award)

� distinctions other than degrees

o membership of professional and learned societies

o recognitions and prizes

o teaching and research experience

o administrative and management experience

o grants obtained

o publications

To [email protected]

Applications should be made electronically in Word or PDF format.

Please ensure you quote “MRC Centre for Transplantation

Informal enquiries may be made to Dr H

Manager on [email protected]

Closing date: 19th

February 2014 5pm; shortlisted candidates will be invited for interview.

T

RC Centre for Transplantation Bridging Fellowship


School of Medicine

position, please send the following:

a copy of a current curriculum vitae, which should include inter alia:

your full name with title

details of your present post with date of appointment

degrees (subject, class, institution, date of award)

other academic/professional qualifications (subject, level, institution, date of award)

distinctions other than degrees

membership of professional and learned societies

teaching and research experience

rative and management experience

onically in Word or PDF format.

MRC Centre for Transplantation Bridging Fellowship” on all correspondence.

Informal enquiries may be made to Dr Hélène Crutzen, Divisional and MRC Centre for Transplantation

[email protected] .

ry 2014 5pm; shortlisted candidates will be invited for interview.

Template version: September 2013

RC Centre for Transplantation Bridging Fellowship


other academic/professional qualifications (subject, level, institution, date of award)

on all correspondence.

MRC Centre for Transplantation

ry 2014 5pm; shortlisted candidates will be invited for interview.

Equal opportunities

King’s College London recognises that equality of opportunity and the recognition and promotion of diversity

are integral to its academic and economic strengths. The following principles apply in respect of the College’s

commitment to equality and diversity:

• To provide and promote equality of opportunity in all areas of its work and activity;

• To recognise and develop the diversity of skills and talent within its current and potential community;

• To ensure that all College members and prospective members are treated solely on the basis of their merits,

abilities and potential without receiving any unjustified discrimination or unfavourable treatment on

grounds such as age, disability, marital status, pregnancy or maternity, race, religion or belief, sex, sexual

orientation, trans status, socio-economic status or any other irrelevant distinction;

• To provide and promote a positive working, learning, and social environment which is free from prejudice,

discrimination and any forms of harassment, bullying or victimisation;

• To foster good relations between individuals from different groups and tackle prejudice and promote

understanding.

Athena SWAN

The Athena SWAN Charter recognises excellence in an institution's commitment to gender equality

in Science, Technology, Engineering, Mathematics and Medicine (STEMM) subjects.

King's has been a member of the Athena SWAN Charter since 2007 and gained its Bronze institutional award

in 2008. The Athena SWAN agenda forms part of a wider suite of diversity and inclusion work streams.

Working with the Charter is helping King's to identify best practice for the working environment of all staff

working in science disciplines.

Applicants with disabilities

King’s College London is keen to increase the number of disabled people. We therefore encourage

applications from individuals with a disability who are able to carry out the duties of the post. If you have

special needs in relation to your application please contact the Department responsible for the administration

of the post.

Travel expenses

The College normally reimburses reasonable travel costs to and from interview within the United Kingdom.

Regrettably, only limited contribution to travel costs for applicants from outside the UK may be available.

Please contact the Head of Department before making your reservation.

Response

We very much regret that due to limited resources and the large number of applications we currently receive,

we are only able to inform short listed candidates of the outcome of their application.

If you do not hear from us within four weeks of the closing date, please assume that you have been

unsuccessful on this occasion. We would like to assure you, however, that every application we receive is

considered in detail and a shortlist only drawn up after careful reference to a detailed person specification.

If therefore, your application is not successful, we hope that you will not be discouraged and will still apply

for other suitable vacancies as and when they are advertised.

Further particulars

The Division

The Division of Transplantation Immunology & Mucosal Biology incorporates research in transplantation and

associated specialities of kidney, liver, gastrointestinal and urinary tract diseases. It unites expertise in basic

immunology and transplantation biology at King’s with clinical research teams at Guy’s and St Thomas’ NHS

Trust and King’s College Hospital who manage some of the largest transplant-patient cohorts in Europe to

deliver excellence in research at an internationally competitive level, and pursue top quality patient-

orientated studies.

The Division covers a broad range of basic and clinical investigation. It fosters a spirit of collaborative research

and aims to pursue excellence in fundamental medical science as well as translational research, throughout

the related clinical research fields at King’s Health Partners. The MRC Centre for Transplantation sits within

the Division as well as working with research teams in Immunology, Genetics, Dermatology, Imaging, Dental

and the School of Law and Ethics.

Research Departments and Heads:

• Experimental Immunobiology- Professor Graham Lord

• Immunoregulation & Immune Intervention- Professors Giovanna Lombardi and Randy Noelle

• Innate Immunity- Professor Anthony Dorling

• Liver Sciences- Professor Alberto Sanchez-Fueyo

• Renal Sciences- Professor Bruce Hendry

The five research sections are based over Guy’s and Denmark Hill campuses of King’s College London with

close integration with the two local NHS Trusts – King’s College Hospital and Guys’ and St Thomas’. The main

administrative offices for the Division are located in Guy’s Hospital, Guy's Campus of King's College London

and house the Head of Division, Professor Steven Sacks, the Divisional Manager, Dr Hélène Crutzen and some

of the administrative and support team.

The MRC Centre for Transplantation

The MRC Centre for Transplantation was established at King's College London in 2007 and was recently

awarded funding from the Medical Research Council for another five years until 2017.

The Centre's main aim is to bring the benefits of excellent research to people by translating basic discovery

into new therapeutic, diagnostic and prognostic application.

The MRC Centre for Transplantation spans four research themes:

1. Overcoming early inflammation after transplantation using cytoprotective therapy

2. Networks that regulate tolerance and promote long term graft acceptance

3. Immune prediction and monitoring as a guide to patient care

4. Investigating the inflammatory and immune response by external imaging

Its science base cuts across liver, kidney, pancreas, bone marrow, islet, hepatocyte and stem cell

transplantation, in what is one of the largest patient groups in Europe.

The Centre incorporates a training theme in research ethics and legislation via links with the Centre of

Medical Law and Ethics at KCL. The MRC Centre is closely linked with the Transplant theme of the NIHR

Comprehensive Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust.

The main administrative offices for the Centre are located in Guy’s Hospital, Guy's Campus of King's College

London and house the Centre Director, Professor Steven Sacks, Deputy Director, Professor Anthony Dorling,

the Centre Manager, Dr Hélène Crutzen and the administrative and support team.

MRC Centre for Transplantation (UK)-Emory University (USA) Bridging Fellowship Scheme

The proposed programme aims to create a link between two progressive clinical-academic transplant centres

and to develop synergies that contribute to the development of world-class academic healthcare.

This collaboration is intended to add value through joint research that would not have been possible at either

Centre alone.

Emory University School of Medicine, USA, has 2,328 full- and part-time faculty and 833 volunteer faculty. The

school had more than 6,600 applications in 2012 for 138 first-year medical student positions. This racially

diverse class has an even mix of men and women, and more than half of its members are nontraditional,

meaning that they were out of college for at least a year before entering medical school. In 2012, the pass

rate for first-time takers of steps 1 and 2 of the National Board Exam (testing basic science and clinical

knowledge and skills) was 99% and 100%, respectively. Since the establishment of the Department of Surgery

in 1930, it has been essential to shaping the Emory University School of Medicine into one of the nation's top

institutions for biomedical education, research and patient care.

The Department offers prospective residents many opportunities for a rich and rewarding training experience,

including diverse practice settings in seven facilities; nationally prominent faculty; and residency and

fellowship programs in breast cancer, cardiothoracic surgery, endosurgery, general surgery, oral and

maxillofacial surgery, pediatric surgery, plastic and reconstructive surgery, transplantation, trauma/surgical

critical care, and vascular surgery. The Emory Transplant Center (ETC) has 45 faculty members who include

basic scientists and clinical researchers across departments ranging from surgery to medicine to pediatrics.

The highly skilled staff of transplant specialists offers comprehensive treatment and support, and no Georgia

transplant center offers better access to cutting-edge transplant technology. They are committed to providing

our patients superior quality outcomes, and to developing new transplant therapies to prevent or delay organ

failure through ground-breaking clinical research.

Benefits of the Emory-MRC Centre link in Transplantation Science:

1. By spending time at Emory candidates will gain access and expertise in experimental models not

available at the MRC Centre for Transplantation

2. Candidates will strengthen their track record of research and add value to their CV and future grant

applications

3. This placement will offer numerous unique opportunities for networking in the field of Transplantation

The Post

The MRC Centre for Transplantation is seeking to identify two outstanding medical or surgical trainees who

are committed to a clinical-academic career and are willing to undertake a one-year collaborative research

placement including the opportunity to spend up to 12 months at Emory University School of Medicine

Department of Surgery. The candidates may already hold a research degree (e.g. PhD) or may be aiming to

undertake PhD training. The successful candidates will be motivated to furthering their training at the MRC

Centre for Transplantation. The Bridging Fellowship at Emory will be funded for up to 12 months, during which

time the successful candidates will be expected to submit a grant application (with guidance from their

Emory/MRC mentors) based on their research experience, with a view to extending their research training at

the MRC Centre. Applicants should be able to demonstrate strategic fit, i.e. alignment with existing

programmes within the MRC Centre and Emory.

Job description

Post title MRC Centre for Transplantation Bridging Fellowship

Department/Division/Directorate MRC Centre for Transplantation, Division of Transplantation Immunology

& Mucosal Biology

Funding Up to £43,745 per annum.

Other benefits Two return flights to USA (economy/ standard class) up to £1500.

Responsible for N/A

Responsible to Professor Steven Sacks, Head of Division

Role purpose

The MRC Centre for Transplantation is seeking to identify two outstanding medical trainees from within the

MRC Centre and clinical partners to undertake a one-year collaborative research placement including the

opportunity to spend up to 12 months at Emory University School of Medicine Department of Surgery.

Applications will be assessed by the MRC Centre Governance and Training group. The two shortlisted

candidate trainees should be committed to furthering their academic training at the MRC Centre for

Transplantation, both to fulfil the goals of the KCL-Emory scheme and act as ambassadors for the Centre while

at Emory. The fellowship scheme provides up to 12 months salary funding with the aim of successful

applicants securing an externally funded research fellowship/career development award at some point during

the fellowship to support their transition to further academic training within the MRC Centre for

Transplantation.

Role outline

Key responsibilities and objectives of the job.

• Prepare applications to secure funding from a major research funding body for a career development award

or other relevant research fellowship award(with guidance from their Emory/MRC mentors).

• Contribute to the design of a range of experiments in relation to the projects agreed with Head of Department.

• Set up and run experiments in consultation with Supervisor ensuring that all experiments are appropriately

supervised and supported.

• Record, analyse and write up the results of experiments.

• Prepare and present findings of research activity to colleagues for review purposes.

• Contribute to the drafting and submitting of papers to appropriate peer reviewed journals.

• Contribute to the overall activity of the research team, Department and Emory as required

• Hold responsibility for ensuring that equipment is safe and maintained in working order and assist with

laboratory upkeep

• Carry out any other duties as are within the scope, spirit and purpose of the job as requested by the line

manager or Head of Department.

Specific Aspects - indicate frequency D (daily), W (weekly), M (monthly) where applicable:

Intensive Display Screen Equipment work (eg.

data entry or digital microscopy):

D Direct patient contact involving exposure prone

procedures (EPP):

Heavy manual handling: Direct patient contact, no EPP W

Highly repetitive tasks (eg. pipetting or re

shelving books):

Shift work, night work or call-out duties:

Work involving risk of exposure to

environmental or human pathogens (eg. in

waste streams or soils):

Driving vehicles on College business:

Work at height (eg. ladders, scaffolds etc)

Organisational chart

Special requirements

• You will be required to work irregular hours in accordance with the needs of the role.

• Information of a confidential nature must be kept strictly confidential and

inside or outside work. It should be noted that breach of confidentiality is a serious offence which may lead

to dismissal.

• This appointment is subject to obtaining the necessary required clearance (for example:

immigration rules and obtain necessary paperwork to visit USA for up to 12 months

this post you will be expected to obtain the necessary clearance before you can take up the post.

General

You will be expected to adhere to King

Date

28th

January 2014

Highly repetitive tasks (eg. pipetting or re- D Work with patient specimens (eg. blood or tissue

samples):

Work with GM organisms or biological agents that

may pose a hazard to human health:

environmental or human pathogens (eg. in

Hazards which require health surveillance eg.

respiratory sensitisers (allergens, substances with risk

phrase R42, wood dust etc) or loud noise:

Food handling or preparation:

Work at height (eg. ladders, scaffolds etc) Work in confined spaces (eg. sump rooms, etc)

You will be required to work irregular hours in accordance with the needs of the role.

Information of a confidential nature must be kept strictly confidential and should never be disclosed either


obtaining the necessary required clearance (for example:

immigration rules and obtain necessary paperwork to visit USA for up to 12 months

expected to obtain the necessary clearance before you can take up the post.

expected to adhere to King’s and Emory University policies and procedures.

Work with patient specimens (eg. blood or tissue W

Work with GM organisms or biological agents that

may pose a hazard to human health:

W

health surveillance eg.

respiratory sensitisers (allergens, substances with risk

phrase R42, wood dust etc) or loud noise:

confined spaces (eg. sump rooms, etc)

You will be required to work irregular hours in accordance with the needs of the role.

should never be disclosed either


obtaining the necessary required clearance (for example: comply with USA

immigration rules and obtain necessary paperwork to visit USA for up to 12 months). Should you be offered

expected to obtain the necessary clearance before you can take up the post.

policies and procedures.

Please note

This job description reflects the core activities of the secondment and as the College and the post-holder

develop there will inevitably be changes in the emphasis of duties. It is expected that the post-holder

recognise this and adopt a flexible approach to work and be willing to participate in training.

Person specification This appointment is subject to obtaining the necessary clearance (for example: comply with USA

immigration rules and obtain necessary paperwork to visit USA for up to 12 months). Should you be offered

this post you will be expected to obtain the necessary clearance before you can take up the post.

Criteria E

S

S

E

N

T

I

A

L

D

E

S

I

R

A

B

L

E

HOW IDENTIFIED

AND ASSESSED

AP Application

AS Assessment

I Interview

P Presentation

R References

Education/qualification and training

Medical Bachelors degree *

Evidence of achievement of Foundation competences or equivalent *

Higher degree (MD, PhD or equivalent) in a relevant subject area *

GMC registration *

Evidence of commitment to specialty *

Knowledge/skills

Demonstration of acquisition of the level of knowledge and skills necessary for the

achievement of Foundation and clinical (matched to the entry level) competencies or

equivalent

*

Demonstration of understanding of, and commitment to, an academic career *

Evidence of team working skills *

Prizes or distinctions *

Experience

Demonstration of the potential for scientific independence and the ability to lead a

research team *

Presentation of work at a national or international meeting *

Significant publications in peer reviewed journals *

Personal characteristics/other requirements

Potential to become a leader in chosen field *

Ability to work in a team *

Ability to lead a project *

Organised *

Efficient *

Ability to adapt to a new working and living environment and situations *

Ability and eagerness to travel abroad *

Summary of terms and conditions of service

Period of Appointment Fixed-term for 12 months

Funding Up to £43,745 per annum.

Other benefits Two return flights to USA (economy/ standard class) up to £1500.

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