Dr. SYED MOHD DANISH RIZVIAssistant ProfessorDepartment of Pharmacology & Toxicology,College of Pharmacy, University of Hail, Hail, K.S.A.Cell: +966556954571Email: syedrizvi10@yahoo.com; sm.danish@uoh.edu.sa http://orcid.org/0000-0002-3106-4707https://scholar.google.co.in/citations?user=e3rjP04AAAAJ&hl=en

Professional Qualification:

Ph.D. in Biotechnology from Integral University, Lucknow. CSIR – NET (LS) Qualified with 0114/0981 rank in December, 2010. CSIR – NET (LS) Qualified with 0188/1065 rank in June, 2010. M.Sc. Biotechnology with 74% marks from Jamia Hamdard University, New Delhi. B.Sc. Medical microbiology with 81.69% marks from Doon P.G. Paramedical College

(HNB Garhwal University), Uttaranchal. Intermediate/12th with 65.6% marks from C.B.S.E. Board, New Delhi. High School/10th with 73.2% marks from C.B.S.E. Board, New Delhi.

Teaching Experience: 5.5 years [Including Post-Ph.D. ~ 2 years]

8 months work experience as Lecturer in Biotechnology at Prakash institute, Greater Noida.1 year experience as Lecturer in Department of Biosciences at Integral University, Lucknow. 3.9 years experience as Assistant Professor in Department of Biosciences at Integral University, Lucknow. Currently joined as an Assistant Professor in Department of Pharmacology & Toxicology at University of Hail, Hail, K.S.A. on 26th October 2016.

PROJECT:

Early Career Research Project on "Designing nano-chaperones for targeting amyloid-beta peptide and islet amyloid polypeptide aggregation: a step towards better medication for Alzheimer’s disease and Type2 Diabetes Mellitus".

Project approval number: ECR/2016/000167 Time Duration: 3years

Approval Date: 11-May-2016 Amount Funded: ~ Rs. 48 Lacs.

Scheme: Early Career Research Award

Funding Agency: DST (Department of Science and Technology), SERB (Science and Engineering Board), Government of India, New Delhi.

PATENTS:

1. Patent filed with Application no. 805/DEL/2012 Title of Invention “A PROCESS FOR THE SYNTHESIS OF MONODISPERSED GOLD NANOPARTICLES IN A SINGLE-STEP PROCESSING USING BROMELAIN” Applicant(s): Mohd. Sajid Khan and Syed Mohd. Danish Rizvi Inventor(s): Mohd. Sajid Khan and Syed Mohd. Danish Rizvi

2. Patent filed with Application no. 1803/DEL/2013 Title of Invention “GOLD NANOPARTICLES FOR BROMELAIN DELIVERY” Applicant(s): Mohd. Sajid Khan and Syed Mohd. Danish Rizvi Inventor(s): Mohd. Sajid Khan, Syed Mohd. Danish Rizvi and Salman Khan

Area of Research:

Enzyme kinetics and Bioinformatics (Thirteen publications): In silico and in vitro testing for the development of multitarget drugs: linkage between Alzeihmer’s Disease and other diseases.

Microbiology (Thirteen publications): Identifying and isolating multidrug resistant strains [ESBL positive] from the clinical samples. Developing strategies to combat multidrug resistance in Bacteria

Nanotechnology (Two patents filed and three publications): Synthesis of inorganic nanoparticles and using them as targeted drug delivery system.

Total Patents Filed: 02 Total Publications: 32 Total Impact factor: 51.716

Publications:

1. Rizvi S.M., Shaikh, S., Naaz, D., et al. 2016, Kinetics and Molecular Docking Study of an Antidiabetic Drug Glimepiride as Acetylcholinesterase Inhibitor: Implication for Alzheimer's Disease Diabetes Dual Therapy. Neurochemical Research 41(6):1475-82. (Impact Factor: 2.472)

2. Shaikh S., Rizvi S.M., Suhail T., Shakil S. et al. 2016, Prediction of Anti-Diabetic Drugs as Dual Inhibitors Against Acetylcholinesterase and Beta-Secretase: A Neuroinformatics Study. CNS Neurol Disord Drug Targets 15(10):1216-1221. (Impact Factor: 2.599)

3. Shaikh, S., Rizvi, S.M., Shakil, S., Riyaz, S., Biswas, D., Jahan, R. 2016, Forxiga (dapagliflozin): Plausible role in the treatment of diabetes-associated neurological disorders. Biotechnol Appl Biochem 63(1):145-50. (Impact Factor: 1.429)

4. Ahmad S.S., Akhtar S., Jamal Q.M., Rizvi S.M., Kamal M.A. et al. 2016, Multiple Targets for the Management of Alzheimer's Disease. CNS Neurol Disord Drug Targets 15(10):1279-1289. (Impact Factor: 2.599)

5. Shaikh S., Rizvi S.M., Anis R., Shakil S. 2016. Prevalence of CTX-M resistance marker and integrons among Escherichia coli and Klebsiella pneumoniae isolates of clinical origin. Lett Appl Microbiol. 62, 419-427. (Impact Factor: 1.579)

6. Shaikh S., Rizvi S.M., Shakil S., et al. 2016, Non-clonal dissemination of Extended-spectrum beta lactamase-producing Pseudomonas aeruginosa strains of clinical origin. Iranian Journal of Science and Technology Transactions A: Science (Accepted: Article in Press). (Impact Factor: 0.128)

7. Shaikh, S., Shakil, S., Rizvi, S.M., Roberts, P.M., Kamal, M.A. 2015, Nanobiotechnological approaches against multidrug resistant bacterial pathogens: An Update. Current Drug Metabolism 16(5): 362-70. (Impact Factor: 3.22)

8. Khan S., Rizvi S.M., Avaish M., Arshad M. et al. 2015, A novel process for size controlled biosynthesis of goldnanoparticles using bromelain. Materials Letters 159: 373–376. (Impact Factor: 2.437)

9. Khan, S., Rizvi, S.M., Ahmad, V. et al. 2015, Magnetic Nanoparticles: properties, synthesis and biomedical applications. Current Drug Metabolism 16(8): 685-704.(Impact Factor: 3.22)

10. Shaikh, S., Fatima, J., Shakil, S., Rizvi, S.M., Kamal, M. A. 2015, Risk factors for acquisition of extended spectrum beta lactamase producing Escherichia coli and Klebsiella pneumoniae in North-Indian hospitals. Saudi Journal of Biological Sciences 22, 37-41. (Impact Factor: 1.781)

11. Shaikh, S., Fatima, J., Shakil, S., Rizvi, S.M., Kamal, M. A. 2015, Prevalence of multidrug resistant and extended spectrum beta-lactamase producing Pseudomonas aeruginosa in a tertiary care hospital. Saudi Journal of Biological Sciences 22:62-64. (Impact Factor: 1.781)

12. Sibhghatulla S., Aaqil H., Rizvi S.M., Shakil S. et al. 2015, Comparative inhibition study of compounds identified in the methanolic extract of Apamarga Kshara against Trichomonas vaginalis carbamate kinase (TvCK): An enzoinformatics approach. Interdisciplinary Sciences: Computational Life Sciences. (Epub ahead of print PMID:26310620) (Impact Factor: 0.853)

13. Shaikh, S., Fatima, J., Shakil, S., Rizvi, S.M. et al. 2015, Antibiotic resistance and extended spectrum beta-lactamases: types, epidemiology and treatment. Saudi Journal of Biological Sciences 22: 90-101. (Impact Factor: 1.781)

14. Rizvi S.M., Shaikh S., Waseem S.M.A., Shakil S., Abuzenadah A.M. et al. 2015, Role of anti-diabetic drugs as therapeutic agents in Alzheimer's disease. EXCLI Journal 14: 684-696. (Impact Factor: 1.292)

15. Khan, S., Rizvi, S.M., Saeed, M. et al. 2014, A Novel Approach for the Synthesis of Gold Nanoparticles Using Trypsin. Advanced Science Letters 20(5-6): 1061-1065. (Impact Factor: 1.253)

16. Baig, M.H.†, Rizvi, S.M.†, Shakil, S., Kamal, M.A., et al., 2014, A Neuroinformatics study describing molecular interaction of cisplatin with acetylcholinesterase: a plausible cause for anticancer drug induced neurotoxicity, CNS & Neurological Disorders Drug Targets 13(2):1-6. (Impact Factor: 2.599) [†Equally contributing authors]

17. Alam, A., Shaikh, S., Ahmad, S.S., Ansari, M.A., Shakil, S., Rizvi, S.M. et al., 2014, Molecular interaction of human brain acetylcholinesterase with a natural inhibitor Huperzine-B: An Enzoinformatics approach. CNS Neurol Disord Drug Targets 13(3):487-490. (Impact Factor: 2.599)

18. Shaikh, S., Verma, A., Siddiqui, S., Ahmad, S.S., Rizvi, S.M., et al., 2014, Current acetylcholinesterase-inhibitors: A Neuroinformatics perspective. CNS Neurol Disord Drug Targets 13(3): 391-401. (Impact Factor: 2.599)

19. Rizvi, S.M., Shakil, S., Biswas, D., Shakil, S. et al., 2014, Invokana (Canagliflozin) as a dual inhibitor of AChE and SGLT2: Advancement in Alzheimer-Diabetes type 2 Linkage via an enzoinformatics study. CNS Neurol Disord Drug Targets 13(3):447-451. (Impact Factor: 2.599)

20. Shaikh, S., Ahmad, S.S., Ansari, M.A., Shakil, S., Rizvi, S.M. et al., 2014, Prediction of comparative inhibition efficiencies for a novel natural ligand, galangin against human brain Acetylcholinesterase, Butyrylcholinesterase and 5-Lipoxygenase: A Neuroinformatics Study. CNS Neurol Disord Drug Targets 13(2):452-459. (Impact Factor: 2.599)

21. Rizvi, S.M., Shakil, S., Zeeshan, M., Khan, M.S., et al., 2014, An enzoinformatics study targeting polo-like kinases-1 enzyme: comparative assessment of anticancer potential of compounds isolated from leaves of Ageratum houstonianum, Pharmacognosy Magazine 10(37):14-21.(Impact Factor: 0.831)

22. Verma, A., Rizvi, S.M., Shaikh, S., Afaque, M., et al., 2014, Compounds isolated from Ageratum houstonianum inhibit the activity of Matrix Metalloproteinases (MMP-2 and MMP-9): An Oncoinformatics Study, Pharmacognosy Magazine 10 (37): 18-26.(Impact Factor: 0.831)

23. Shaikh, S.†, Rizvi, S.M.†, Hameed, N., Biswas, D., Khan, M. et al. 2014, Aptiom (Eslicarbazepine acetate) as a dual inhibitor of β-secretase and Voltage-gated sodium channel: advancement in Alzheimer’s disease-Epilepsy linkage via an enzoinformatics study. CNS Neurol Disord Drug Targets 13(7): 1258-62. (Impact Factor: 2.599) [†Equally contributing authors]

24. Rizvi, S.M., Shaikh, S., Shakil, S., et al. 2014, Fetzima (levomilnacipran), a drug for major depressive disorder as a dual inhibitor for human serotonin transporters and beta-site amyloid precursor protein cleaving enzyme-1. CNS Neurol Disord Drug Targets 13(8): 1427-31. (Impact Factor: 2.599)

25. Ansari, M.A., Shaikh, S., Shakil, S., Rizvi, S.M., 2014, An Enzoinformatics Study for Prediction of Efficacies of Three Novel Penem Antibiotics against New Delhi Metallo-β-lactamase-1 Bacterial Enzyme. Interdisciplinary Sciences: Computational Life Sciences 6:1-8. (Impact Factor: 0.853)

26. Shaikh, S., Rizvi, S.M., Tripathi, R., Biswas, D. et al. 2014, Effect of degree of unsaturation of fatty acids on the activity of FabI (enoyl-acyl carrier protein reductase) enzyme from Plasmodium falciparum: an enzoinformatics study. Asian Pacific Journal of Tropical Disease 4(1): 670-675.

27. Rizvi, S.M., Shakil, S., Haneef, M., 2013, A simple click by click protocol to perform docking: AutoDock 4.2 made easy for Non-Bioinformaticians, EXCLI journals 12:831-857. (Impact Factor: 1.292)

28. Ansari, M.A., Alam, A., Ghazal, F., Tripathi, R., Shakil, S., Rizvi, S.M., et al., 2013, Role of Matrix-Metalloproteinases (MMPs) in Cancer. In “Advances In Protein Chemistry”, Ashraf GM & Sheikh IA (Eds.). OMICS Group eBooks, Foster City, USA. PP. 4-19.

29. Zeeshan, M., Rizvi, S.M., Khan, M.S. and Kumar, A., 2012, Isolation, partial purification and evaluation of bioactive compounds from leaves of Ageratum houstonianum, EXCLI journals 11:78-88. (Impact Factor: 1.292)

30. Biswas, D., Rizvi, S.M., Suhail, S., Khan, M.S., et al., 2012, Cyanobacterium Nostoc muscorum as a new model system to evaluate the cytotoxicity induced by curcumin and quercetin: First Report, Biochemical cellular archive 12(1): 185-188.

31. Rizvi, S.M., Zeeshan, M., Khan, S., Biswas, D., et al., 2011, Evaluation and distribution of antibacterial potential in the aerial parts of wild Tridax procumbens, Journal of Chemical and Pharmaceutical Research 3(2):80-87.

32. Rizvi, S.M., Biswas, D. et al., 2011, In-vitro antibacterial and antioxidant potential of leaf and flower extracts of Vernonia sp. and their phytochemical constituents, International Journal of Pharmaceutical Sciences Review and Research 9(2): 164-169.

Database:

ADNCD: Anti-diabetic natural compound database [http://www.adncd.com/]

International Collaboration:

Novel Global Community Educational Foundation, Australia [http://www.ngcef.net/]

Honorary Faculty Member

Member of NGCEF Research committee

Conferences:

Attended national symposium on Biodiversity & food security challenges and devising strategies at IIPR, Kanpur from 10th to 11th December, 2011.

Attended national level workshop on Fundamentals of Nanoscience and Biotechnology at Integral University, Lucknow from 28th to 30th January, 2013.

Attended national seminar on Proteomics Based Biomarkers for animal and Plant diseases at Jamia Hamdard, New Delhi from 1st to 2nd March, 2013.

Attended international conference on Nanoscience and Nanotechnology ICNN-2013 at Babasaheb Bhimrao Ambedkar University, Lucknow from 18th to 20th

Nov, 2013.

Attended national level workshop on Intellectual Property System: India Today & Tomorrow at Integral University, Lucknow on 10th Jan, 2014.

Attended national level workshop on Role of Nanomedicines on Therapeutic agents against Multi-drug Resistant Pathogens NWN-2014 at Integral University, Lucknow from 7th March to 9th March, 2014.

Attended national level workshop on Data analysis by SPSS at Integral University, Lucknow on 25th Feb, 2015.

Attended national conference on Novel Tools and Treatment Approaches in Health Care System at Integral University, Lucknow on 3rd March, 2015.

Attended national conference on Nanoscience, Nanotoxicology and Nanoinformatics- Present and Future Perspectives at Integral University, Lucknow from 14th March to 15th March, 2015.

Attended international conference on New frontiers in Industrial and Applied Biotechnology “GenoPro 2015” at Department of Biotechnology, Invertis University, Bareilly from 18th to 19th September, 2015.

Attended a workshop on “Oil conservation” organized by Petroleum conservation research association, Govt. of India, at Integral University, Lucknow on 1st

August, 2015.

Member of organizing committee as Treasurer in International Conference on Biotechnological Advancements in Free Radical Biology and Medicine “ICBAFM-2015” at Department of Biosciences and Bioengineering, Integral university, Lucknow from 14th to 16th November, 2015.

Attended a seven day faculty development programme on “MATLAB” at Integral University, Lucknow from 1st to 7th February, 2016.

Attended a national conference on “Business and public policy focus on Uttar Pradesh” at Integral University, Lucknow from 18th to 19th March, 2016.

Attended a national conference on “Intellectual Property Rights: A significant tool for sustainable agriculture” at Integral University, Lucknow from 2nd to 3rd April, 2016.

Personal Profile:Date of birth: 10th December 1984

Fathers name: Late Dr. Syed Mohd. Aaqil Rizvi

Sex: Male

Marital status: Married

References:

Dr. Shazi ShakilScientist, KACST Technology Innovation Center in Personalized Medicine;Assistant Professor, Department of Medical Laboratory Technology, Faculty of Applied Medical SciencesKing Abdulaziz University,P.O. Box 80216, Jeddah 21589 Saudi ArabiaTel: +966-581491176Fax: +966-2-6400000-20171Email ID: shazibiotech@gmail.com; Alternate Email (institutional): sfaruqi@kau.edu.sa  Prof. Mohammad A. Kamal (PhD, MRACI C Chem) Enymoics, 7 Peterlee PI, Hebersham NSW 2770, Australia Email: prof.makamal@lycos.com eFax: 15016368847

Dr. Aamir NazirSenior ScientistToxicology DivisionCentral Drug Research Institute,Lucknow (U.P.)-226 031 (INDIA)EmailID: anazir@cdri.res.in Phone: +91-522-2772450 Ext. 4583